Methods and compositions for identifying castration resistant neuroendocrine prostate cancer

ABSTRACT

The present invention is based on the identification of castration resistant neuroendocrine prostate cancer (CRPC-NE) features in the circulation, and relates to methods and compositions of identifying CRPC-NE patients by detecting these features.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims the benefit of priority to U.S. ProvisionalApplication Ser. No. 62/975,009, filed on 11 Feb. 2020; the entirecontents of said application is incorporated herein in its entirety bythis reference.

STATEMENT OF RIGHTS

This invention was made with government support under grant number P50CA211024 awarded by the National Institutes of Health. The governmenthas certain rights in the invention.

BACKGROUND OF THE INVENTION

Prostate cancer is a leading cause of cancer death for men worldwide(Siegel, Miller, and Jemal (2019) CA Cancer J Clin 69:7-34). Despitesignificant advances in therapy for patients with metastatic disease,the emergence of treatment resistance remains a universal problem whichultimately contributes to the lethality of the disease. Prostate canceris a cancer type that is driven by androgen receptor (AR) signaling, andseveral potent drugs targeting the AR are now commonly used to treatpatients with advanced disease either in combination with gonadalandrogen suppression therapy for metastatic hormone naive prostatecancer or in the castration resistant setting. Resistance to potent ARtargeted drugs is still primarily mediated through AR-signaling (Watson,Arora, and Sawyers (2015) Nat Rev Cancer 15:701-711). However, anincreasingly recognized proportion of tumors develop histologictransformation to a castration resistant neuroendocrine prostate cancer(CRPC-NE) phenotype as a mechanism of AR-independent treatmentresistance (Beltran et al. (2019) Clin Cancer Res 25:6916-6924; Abida etal. (2019) Proc Natl Acad Sci USA 116:11428-11436; Aggarwal et al.(2018) J Clin Oncol JCO2017776880). Metastatic biopsies demonstratemorphologic features of small cell carcinoma, often with low or absentexpression of the AR, downregulation of downstream AR-regulated markerssuch as prostate specific antigen (PSA), and expression of classicalneuroendocrine markers (e.g., chromogranin, synaptophysin) (Epstein etal. (2014) Am J Surg Pathol 38:756-767; Beltran et al. (2011) CancerDiscov 1:487-495). The prognosis of CRPC-NE is poor due in part to latediagnosis and a lack of effective therapies (Aggarwal et al. (2018) JClin Oncol JCO2017776880; Conteduca et al. (2019) Eur J Cancer121:7-18). Similar to other poorly differentiated neuroendocrinecarcinomas (Rickman et al. (2017) Nat Med 23:1-10; George et al. (2015)Nature 524:47-53), CRPC-NE frequently harbors genomic loss of RB1 andTP53 (Abida et al. (2019) Proc Natl Acad Sci USA 116:11428-11436;Epstein et al. (2014) Am J Surg Pathol 38:756-767; Beltran et al. (2011)Cancer Discov 1:487-495; Beltran et al. (2016) Nat Med 22:298-305; Tanet al. (2014) Clin Cancer Res 20:890-903). However, RB1 and TP53loss-of-function alterations are not specific to CRPC-NE and alsoobserved in a subset of castration resistant adenocarcinomas (Abida etal. (2019) Proc Natl Acad Sci USA 116:11428-11436). Prior clinical andpreclinical studies have supported a transdifferentiation processwhereby CRPC-NE evolves clonally from a luminal prostate adenocarcinomaprecursor (Beltran et al. (2016) Nat Med 22:298-305; Zou et al. (2017)Cancer Discov 7:736-749; Ku et al. (2017) Science 355:78-83; Mu et al.(2017) Science 355:84-88; Park et al. (2018) Science 362:91-95). Earlyprostate cancer genomic alterations are retained, but other genomic andepigenetic alterations are acquired (Beltran et al. (2016) Nat Med22:298-305; Ku et al. (2017) Science 355:78-83; Berger et al. (2019) JClin Invest 130:3924-3940). How and when this lineage plasticitymanifests in patients is not well understood and whether early detectionof CRPC-NE could improve outcomes is not known.

Understanding patterns of tumor evolution that occur during prostatecancer progression and treatment resistance can inform tumor biology aswell as identify novel strategies for combating resistance. Serialmetastatic sampling in patients with prostate cancer during progressionis challenging and is also not always representative of theheterogeneity of alterations that may exist across metastases in anindividual. While rapid autopsy studies have pointed to limitedintra-individual genomic (Kumar et al. (2016) Nat Med 22:369-378) andepigenomic (DNA methylation) (Yegnasubramanian et al. (2004) Cancer Res64:1975-1986; Aryee et al. (2013) Sci Transl Med 5:169ra110)heterogeneity across anatomic sites of metastases at the time of lethaldisease, circulating tumor DNA studies at earlier prostate cancerdisease states indicates clonal dynamics that occur during tumorevolution with competing clones and subclones potentially contributingto resistance and progression (Carreira et al. (2014) Sci Transl Med6:254ra125). Most studies to date have focused on castration resistantadenocarcinoma (CRPC-Adeno), and little is known regarding theunderlying heterogeneity and tumor dynamics in the case of CRPC-NEevolution.

Loss of androgen receptor (AR) signaling dependence occurs inapproximately 15-20% of treatment resistant prostate cancers, and thismay manifest clinically as transformation from a prostate adenocarcinomahistology to a CRPC-NE. The diagnosis of CRPC-NE currently relies on ametastatic tumor biopsy, which is invasive for patients and sometimeschallenging to diagnose due to morphologic heterogeneity. Accordingly, agreat need exists for diagnostic, prognostic, and therapeutic methodsregarding CRPC-NE.

SUMMARY OF THE INVENTION

The present invention is based, at least in part, on the discovery thata targeted set combining genomic (e.g., TP53, RB1, CPLD, AR) andepigenomic (e.g., hypo- and hyper-methylation sites) alterations thatwas capable of identifying patients with CRPC-NE. These genomic andepigenomic alterations were detectable in the circulation andsuccessfully applied to circulating tumor (ctDNA) for identifyingpatients with CRPC-NE.

In one aspect, a method of assessing whether a subject is afflicted withcastration-resistant neuroendocrine prosate cancer (CRPC-NE) or at riskfor developing CRPC-NE, the method comprising determining the presenceor absence of one or more genomic or epigenomic alterations selectedfrom: i) deletion or mutation of at least one biomarker listed in Table1A; ii) gain or mutation of at least one biomarker listed in Table 1B;iii) hypermethylation of at least one genomic site listed in Table 1C;and iv) hypomethylation of at least one genomic site listed in Table 1Din the genomic DNA; wherein the presence of deletion or mutation of atleast one biomarker listed in Table 1A, hypermethylation of at least onegenomic site listed in Table 1C, and/or hypomethylation of at least onegenomic site listed in Table 1D in the genomic DNA; and/or the absenceof gain or mutation of at least one biomarker listed in Table 1B in thegenomic DNA isolated from the biological sample indicates that thesubject is afflicted with CRPC-NE or at risk for developing CRPC-NE,optionally obtaining a biological sample from the subject for thedetermination step, is provided.

Numerous embodiments are further provided that can be applied to anyaspect of the present invention and/or combined with any otherembodiment described herein. For example, in one embodiment, thedeletion or mutation of at least one biomarker listed in Table 1A or thegain or mutation of at least one biomarker listed in Table 1B isdetected by whole exome sequencing (WES). In another embodiment, thehypermethylation of at least one genomic site listed in Table 1C orhypomethylation of at least one genomic site listed in Table 1D isdetected by whole genome bisulfite sequencing (WGBS). In still anotherembodiment, the deletion of at least one biomarker listed in Table 1A isa homozygous deletion, a heterozygous deletion, a copy number neutralloss, or an event defined by loss of one allele and gain of the otherallele. In yet another embodiment, the mutation of at least onebiomarker listed in Table 1A is a non-synonymous single-nucleotidevariant (SNV). In another embodiment, the gain of at least one biomarkerlisted in Table 1B is a focal gain. In still another embodiment, themutation of at least one biomarker listed in Table 1B is anon-synonymous single-nucleotide variant (SNV) (e.g., L702H or T878A ofSEQ ID NO: 48). In yet another embodiment, the hypermethylation of atleast one genomic site listed in Table 1C is defined by a highermethylation level than the site specific tissue-based threshold. Inanother embodiment, the hypomethylation of at least one genomic sitelisted in Table 1C is defined by a lower methylation level than the sitespecific tissue-based threshold. In still another embodiment, thethreshold for each genomic site listed in Table 1C or 1D is apre-determined threshold that discriminates between castration resistantprostate adenocarcinoma (CRPC-Adeno) and CRPC-NE tissue samples. In yetanother embodiment, the method further comprises, after step (c),calculating a neuroendocrine prostate cancer (NEPC) score based on thepresence or absence of one or more genomic or epigenomic featuresdetermined in step (c). In another embodiment, the method furthercomprises comparing the NEPC score to a control, wherein a higher NEPCscore compared to the control indicates that the subject is afflictedwith CRPC-NE or at risk for developing CRPC-NE. In another embodiment,the control is a reference value. In still another embodiment, thecontrol is a NEPC score determined from a control sample. In yet anotherembodiment, the control sample is obtained from a subject withoutCRPC-NE, or a member of the same species to which the subject belongswithout CRPC-NE. In another embodiment, the control sample is obtainedfrom a subject with castration resistant prostate adenocarcinoma(CRPC-Adeno). In still another embodiment, the sample is selected fromthe group consisting of organs, tissue, body fluids and cells. In yetanother embodiment, the body fluid is selected from the group consistingof whole blood, serum, plasma, sputum, spinal fluid, lymph fluid, skinsecretions, respiratory secrections, intestinal secretions,genitourninary tract secretions, tears, milk, buccal scrape, saliva,cerebrospinal fluid, urine, and stool. In another embodiment, the sampleis whole blood, serum or plasma. In still another embodiment, cell-freeDNA (cfDNA) or circulating tumore DNA (ctDNA) isolated from plasma isused for the determination. In still another embodiment, genomic DNAisolated from a tumor cell or tissue is used for the determination. Inyet another embodiment, the method further comprises comparingadditional biomarkers for CRPC-NE, such as a biomarker selected from thegroup consisting of AR, a downstream AR-regulated marker, and aclassical neuroendocrine marker. In another embodiment, the downstreamAR-regulated marker is selected from the group consisting of prostatespecific antigen (PSA), NKX3.1, and TMPRSS2. In still anotherembodiment, the classical neuroendocrine marker is selected from thegroup consisting of chromogranin, synaptophysin, neuron specificenolase, and CD56. In yet another embodiment, the method furthercomprises detecting morphological features of a tumor biopsy from thesubject. In another embodiment, the subject is afflicted withcastration-resistant prostate cancer (CRPC). In still anotherembodiment, the subject is resistant to an androgen receptor(AR)-directed therapy. In yet another embodiment, the method furthercomprises administering to the subject an anti-cancer therapy other thanan AR-targeted therapy as a single agent if the subject is afflictedwith CRPC-NE or at risk for developing CRPC-NE. In another embodiment,the anti-cancer therapy is selected from the group consisting of anepgenitic modifier, targeted therapy, chemotherapy, radiation therapy,and/or hormonal therapy, optionally wherein the anti-cancer therapycomprises an AR-targeted therapy. In still another embodiment, theanti-cancer therapy is administered to the subject in combination withthe AR-targeted therapy, optionally wherein the anti-cancer therapy isadministered before, after, or concurrently with the AR-targetedtherapy. In yet another embodiment, the targeted therapy is animmunotherapy. In another embodiment, the immunotherapy is cell-based.In still another embodiment, the immunotherapy comprises a cancervaccine and/or virus. In yet another embodiment, the immunotherapyinhibits an immune checkpoint, such as an immune checkpoint selectedfrom the group consisting of CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1,B7-H4, B7-H6, ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR familyreceptors, TIM-1, TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA,SIRPalpha (CD47), CD48, 2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT,HHLA2, butyrophilins, and A2aR. In another embodiment, the immunecheckpoint is PD1, PD-L1, or CTLA-4. In still another embodiment, theanti-cancer therapy is a platinum-based chemotherapy.

In another aspect, a method for monitoring the progression of CRPC in asubject, the method comprising: a) detecting in a subject sample at afirst point in time the presence or absence of one or more genomic orepigenomic features selected from: i) deletion or mutation of at leastone biomarker listed in Table 1A; ii) gain or mutation of at least onebiomarker listed in Table 1B; iii) hypermethylation of at least onegenomic site listed in Table 1C; and iv) hypomethylation of at least onegenomic site listed in Table 1D; b) calculating a first NEPC score basedon the presence or absence of one or more genomic or epigenomic featuresdetermined in step a); c) repeating step a) at a subsequent point intime; d) calculating a second NEPC score based on the presence orabsence of one or more genomic or epigenomic features determined in stepc); and e) comparing the NEPC scores determined in steps b) and d), andtherefrom monitoring the progression of CRPC in the subject, isprovided.

In still another aspect, a method of assessing the efficacy of an agentfor treating CRPC-NE in a subject, the method comprising: a) detectingin a subject sample at a first point in time the presence or absence ofone or more genomic or epigenomic features selected from: i) deletion ormutation of at least one biomarker listed in Table 1A; ii) gain ormutation of at least one biomarker listed in Table 1B; iii)hypermethylation of at least one genomic site listed in Table 1C; andiv) hypomethylation of at least one genomic site listed in Table 1D; b)calculating a first NEPC score based on the presence or absence of oneor more genomic or epigenomic features determined in step a); c)repeating step a) during at least one subsequent point in time afteradministration of the agent; d) calculating a second NEPC score based onthe presence or absence of one or more genomic or epigenomic featuresdetermined in step c); and e) comparing the NEPC scores determined fromsteps b) and d), wherein a higher NEPC score determined in thesubsequent sample, relative to the sample at the first point in time,indicates that the agent does not treat CRPC-NE in the subject; andwherein a lower NEPC score determined in the subsequent sample, relativeto the sample at the first point in time, indicates that the agenttreats CRPC-NE in the subject, is provided.

As described above, numerous embodiments are further provided that canbe applied to any aspect of the present invention and/or combined withany other embodiment described herein. For example, in one embodiment,the subject has undergone treatment, completed treatment, and/or is inremission for CRPC-NE between the first point in time and the subsequentpoint in time. In another embodiment, the first and/or at least onesubsequent sample is selected from the group consisting of ex vivo andin vivo samples. In still another embodiment, the first and/or at leastone subsequent sample is obtained from an animal model of CRPC-NE. Inyet another embodiment, the first and/or at least one subsequent sampleis a portion of a single sample or pooled samples obtained from thesubject. In another embodiment, the sample comprises cells, cell lines,histological slides, paraffin embedded tissue, fresh frozen tissue,fresh tissue, biopsies, blood, plasma, serum, buccal scrape, saliva,cerebrospinal fluid, urine, stool, mucus, bone marrow, peritumoraltissue, and/or intratumoral tissue obtained from the subject. In anotherembodiment, the sample is whole blood, serum or plasma. In still anotherembodiment, the sample is a tumor cell or tissue, and genomic DNA isisolated from the plasma and used for detecting the presence or absenceof one or more genomic or epigenomic features. In still anotherembodiment, the sample is plasma, and cell-free DNA (cfDNA) orcirculating tumore DNA (ctDNA) is isolated from the plasma and used fordetecting the presence or absence of one or more genomic or epigenomicfeatures.

In yet another aspect, a cell-based assay for screening for agents thathave a cytotoxic or cytostatic effect on a CRPC-NE cancer cellcomprising, contacting the CRPC-NE cancer cell with a test agent, anddetermining the ability of the teat agent: i) to inhibit deletion ormutation of at least one biomarker listed in Table 1A; ii) to inducegain or mutation of at least one biomarker listed in Table 1B; iii) todecrease the methylation level at least one genomic site listed in Table1C; and/or iv) to increase the methylation level of at least one genomicsite listed in Table 1D in the subject sample, is provided.

As described above, numerous embodiments are further provided that canbe applied to any aspect of the present invention and/or combined withany other embodiment described herein. For example, in one embodiment,the step of contacting occurs in vivo, ex vivo, or in vitro. In anotherembodiment, the assay further comprises administering the test agent toan animal model of CRPC-NE.

In an other aspect, a kit for assessing the ability of a agent to treatCRPC-NE, the kit comprising a reagent for assessing the presence orabsence of one or more genomic or epigenomic features selected from: i)deletion or mutation of at least one biomarker listed in Table 1A; ii)gain or mutation of at least one biomarker listed in Table 1B; iii)hypermethylation of at least one genomic site listed in Table 1C; andiv) hypomethylation of at least one genomic site listed in Table 1D, isprovided.

In still another aspect, a kit for assessing whether a subject isafflicted with CRPC-NE or at risk for developing CRPC-NE, the kitcomprising a reagent for assessing the presence or absence of one ormore genomic or epigenomic features selected from: i) deletion ormutation of at least one biomarker listed in Table 1A; ii) gain ormutation of at least one biomarker listed in Table 1B; iii)hypermethylation of at least one genomic site listed in Table 1C; andiv) hypomethylation of at least one genomic site listed in Table 1D, isprovided.

In yet another aspect, a method of treating a subject afflicted withCRPC-NE comprising administering to the subject a therapeuticallyeffective amount of an agent that modulates the presence or absence ofone or more genomic or epigenomic features selected from: i) deletion ormutation of at least one biomarker listed in Table 1A; ii) gain ormutation of at least one biomarker listed in Table 1B; iii)hypermethylation of at least one genomic site listed in Table 1C; andiv) hypomethylation of at least one genomic site listed in Table 1D, isprovided.

As described above, numerous embodiments are further provided that canbe applied to any aspect of the present invention and/or combined withany other embodiment described herein. For example, in one embodiment,the agent inhibits deletion or mutation of at least one biomarker listedin Table 1A, thereby treating a subject afflicted with CRPC-NE. Inanother embodiment, the agent induces gain or mutation of at least onebiomarker listed in Table 1B, thereby treating a subject afflicted withCRPC-NE. In still another embodiment, the agent decreases themethylation level at least one genomic site listed in Table 1C, therebytreating a subject afflicted with CRPC-NE. In yet another embodiment,the agent increases the methylation level at least one genomic sitelisted in Table 1D, thereby treating a subject afflicted with CRPC-NE.In another embodiment, the agent is an epigenetic modifier, such as anEZH2 inhibitor. In still another embodiment, the method furthercomprises administering to the subject an immunotherapy and/or cancertherapy, optionally wherein the immunotherapy and/or cancer therapy isadministered before, after, or concurrently with the agent. In yetanother embodiment, the immunotherapy is cell-based. In anotherembodiment, the immunotherapy comprises a cancer vaccine and/or virus.In still another embodiment, the immunotherapy inhibits an immunecheckpoint, such as an immune checkpoint is selected from the groupconsisting of CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1, B7-H4, B7-H6,ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR family receptors, TIM-1,TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA, SIRPalpha (CD47), CD48,2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT, HHLA2, butyrophilins, andA2aR. In yet another embodiment, the immune checkpoint is PD1, PD-L1, orCD47. In another embodiment, the cancer therapy is selected from thegroup consisting of radiation, a radiosensitizer, and a chemotherapy. Inanother embodiment, the cancer therapy is a platinum-based chemotherapy.In still another embodiment, the deletion or mutation of at least onebiomarker listed in Table 1A or the gain or mutation of at least onebiomarker listed in Table 1B is detected by whole exome sequencing(WES). In yet another embodiment, the hypermethylation of at least onegenomic site listed in Table 1C or hypomethylation of at least onegenomic site listed in Table 1D is detected by whole genome bisulfitesequencing (WGBS). In another embodiment, the deletion of at least onebiomarker listed in Table 1A is a homozygous deletion, a heterozygousdeletion, a copy number neutral loss, or an event defined by loss of oneallele and gain of the other allele. In still another embodiment, themutation of at least one biomarker listed in Table 1A is anon-synonymous single-nucleotide variant (SNV). In yet anotherembodiment, the gain of at least one biomarker listed in Table 1B is afocal gain. In another embodiment, the mutation of at least onebiomarker listed in Table 1B is a non-synonymous single-nucleotidevariant (SNV) (e.g., L702H or T878A of SEQ ID NO: 48). In still anotherembodiment, the hypermethylation of at least one genomic site listed inTable 1C is defined by a higher methylation level than the site specifictissue-based threshold. In yet another embodiment, the hypomethylationof at least one genomic site listed in Table 1C is defined by a lowermethylation level than the site specific tissue-based threshold. Inanother embodiment, the threshold for each genomic site listed in Table1C or 1D is the threshold that best discriminates between castrationresistant prostate adenocarcinoma (CRPC-Adeno) and CRPC-NE tissuesamples by Receiver operating characteristic (ROC) curve analysis. Instill another embodiment, the agent is administered in apharmaceutically acceptable formulation. In yet another embodiment, thesubject is an animal model of CRPC-NE. In another embodiment, the animalmodel is a rodent model. In still another embodiment, the subject is amammal, such as a mouse or a human.

In yet another aspect, a method is provided for assessing whether asubject is afflicted with or at risk for developing castration-resistantneuroendocrine prostate cancer (CRPC-NE) or castration-resistantadenocarcinoma prostate cancer (CRPC-Adeno), the method comprisingdetermining the presence or absence of one or more genomic or epigenomicalterations in at least one biomarker listed in Table 14, wherein thepresence one or more genomic or epigenomic alterations listed in Table14 in the genomic DNA isolated from the biological sample indicates thatthe subject is afflicted with CRPC-NE or CRPC-Adeno or at risk fordeveloping CRPC-NE or CRPC-Adeno, optionally obtaining a biologicalsample from the subject for the determination step.

As described above, numerous embodiments are further provided that canbe applied to any aspect of the present invention and/or combined withany other embodiment described herein. For example, in one embodiment,the one or more genomic or epigenomic alterations listed in Table 14comprises a mutation detected by whole exome sequencing (WES). Inanother embodiment, the one or more genomic or epigenomic alterationslisted in Table 14 comprises hypermethylation or hypomethylation of atleast one genomic site listed in Table 14 detected by whole genomebisulfite sequencing (WGBS). In still another embodiment, the one ormore genomic or epigenomic alterations listed in Table 14 comprise ahomozygous deletion, a heterozygous deletion, a copy number neutralloss, or an event defined by loss of one allele and gain of the otherallele. In yet another embodiment, the one or more genomic or epigenomicalterations listed in Table 14 is a non-synonymous single-nucleotidevariant (SNV). In one embodiment, the one or more genomic or epigenomicalterations listed in Table 14 is a focal gain of at least one biomarkerlisted in Table 14. In another embodiment, the one or more genomic orepigenomic alterations listed in Table 14 is a non-synonymoussingle-nucleotide variant (SNV). In still another embodiment, thehypermethylation of at least one genomic site listed in Table 14 isdefined by a higher methylation level than the site specifictissue-based threshold. In yet another embodiment, the hypomethylationof at least one genomic site listed in Table 14 is defined by a lowermethylation level than the site specific tissue-based threshold. In oneembodiment, the threshold for each genomic site listed in Table 14 is apre-determined threshold that discriminates between castration resistantprostate adenocarcinoma (CRPC-Adeno) and CRPC-NE tissue samples. Inanother embodiment, the method further comprises after step (c), basedon the presence or absence of one or more genomic or epigenomic featuresdetermined in step (c). In still another embodiment, the method furthercomprises comparing the NEPC score to a control, wherein a higher NEPCscore compared to the control indicates that the subject is afflictedwith CRPC-NE or at risk for developing CRPC-NE. In yet anotherembodiment, the control is a reference value. In one embodiment, thecontrol is a NEPC score determined from a control sample. In anotherembodiment, the control sample is obtained from a subject withoutCRPC-NE, or a member of the same species to which the subject belongswithout CRPC-NE. In still another embodiment, the control sample isobtained from a subject with castration resistant prostateadenocarcinoma (CRPC-Adeno). In yet another embodiment, the sample isselected from the group consisting of organs, tissue, body fluids andcells. In one embodiment, the body fluid is selected from the groupconsisting of whole blood, serum, plasma, sputum, spinal fluid, lymphfluid, skin secretions, respiratory secrections, intestinal secretions,genitourninary tract secretions, tears, milk, buccal scrape, saliva,cerebrospinal fluid, urine, and stool. In another embodiment, the sampleis whole blood, serum or plasma. In still another embodiment, cell-freeDNA (cfDNA) or circulating tumore DNA (ctDNA) isolated from plasma isused for the determination. In yet another embodiment, genomic DNAisolated from a tumor cell or tissue is used for the determination. Inone embodiment, the method

further comprises comparing additional biomarkers for CRPC-NE. In stillanother embodiment, the additional biomarker is selected from the groupconsisting of AR, a downstream AR-regulated marker, and a classicalneuroendocrine marker. In one embodiment, the downstream AR-regulatedmarker is selected from the group consisting of prostate specificantigen (PSA), NKX3.1, and TMPRSS2. In another embodiment, the classicalneuroendocrine marker is selected from the group consisting ofchromogranin, synaptophysin, neuron specific enolase, and CD56. In stillanother embodiment, the method further comprises detecting morphologicalfeatures of a tumor biopsy from the subject. In yet another embodiment,the subject is afflicted with castration-resistant prostate cancer(CRPC). In another embodiment, the subject is resistant to an androgenreceptor (AR)-directed therapy. In still another embodiment, the methodfurther comprises administering to the subject an anti-cancer therapyother than an AR-targeted therapy as a single agent if the subject isafflicted with CRPC-NE or at risk for developing CRPC-NE. In yet anotherembodiment, the anti-cancer therapy is selected from the groupconsisting of an epgenitic modifier, targeted therapy, chemotherapy,radiation therapy, and/or hormonal therapy, optionally wherein theanti-cancer therapy comprises an AR-targeted therapy. In one embodiment,the anti-cancer therapy is administered to the subject in combinationwith the AR-targeted therapy, optionally wherein the anti-cancer therapyis administered before, after, or concurrently with the AR-targetedtherapy. In another embodiment, the targeted therapy is animmunotherapy. In yet another embodiment, the immunotherapy iscell-based. In one embodiment, the immunotherapy comprises a cancervaccine and/or virus. In another embodiment, the immunotherapy inhibitsan immune checkpoint, such as a checkpoint selected from the groupconsisting of CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1, B7-H4, B7-H6,ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR family receptors, TIM-1,TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA, SIRPalpha (CD47), CD48,2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT, HHLA2, butyrophilins, andA2aR. In one embodiment, the immune checkpoint is PD1, PD-L1, or CTLA-4.In one embodiment, the anti-cancer therapy is a platinum-basedchemotherapy.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1A-FIG. 1D show frequencies of somatic aberrations in advancedprostate cancer driver genes. FIG. 1A shows a schematic of study cohort.FIG. 1B shows whole exome sequencing (WES) segmented data for studycohort. WES segmented data are shown raw (inset) and ploidy and tumorcontent (TC) adjusted. FIG. 1C shows a distribution of somatic copynumber loss and SNVs in CRPC-Adeno and CRPC-NE ctDNA and tumor tissuesamples. Loss events include homozygous deletions (HomDel), heterozygousdeletions (HetDel), copy number neutral losses (CNNL) and events definedby loss of one allele and gain of the other allele (Del|Gain). FIG. 1Dshows AR somatic aberrations status in CRPC-Adeno, CRPC-NE and HNPCplasma and tumor tissue samples, ordered based on serial dates ofcollection. AR gain, focal gain and SNV (L702H and T878A positionalpileup calls) are shown together with sample ploidy and tumor class.Statistics are reported in Table 8.

FIG. 2 shows a distribution of tumor content (TC), tumor ploidy, copynumber aberration fraction (CNAF) and total number of somatic SNVscomputed from genomic data across plasma and tumor tissue samples andacross sample types. Reported p-values are computed using two-tailedWilcoxon-Mann-Whitney test. Pie-charts represent for each genomicvariable the fraction of samples for which (white portion) the value wasable to estimate among, respectively, plasma and tissue samples.

FIG. 3A-FIG. 3D show analysis of plasma genomics and clinical variableassociations. FIG. 3A shows a distribution of tumor content (TC)estimation in plasma among patients with different type and number ofmetastasis type. FIG. 3B shows a correlation of TC estimations in plasmaand time to plasma collection from metastasis and number of therapylines before plasma collection. FIG. 3C shows a correlation of TCestimations in plasma and NEPC clinical markers (PSA=prostate specificantigen, NSE=neuron-specific enolase, CGA=chromogranin A) anddistribution of NEPC markers across patient's class at plasmacollection. FIG. 3D shows a distribution of TC, copy number aberrationfraction (CNAF), number of SNVs (outliers not shown) and number ofmissense SNVs (outliers not shown) across patients with or withoutchemotherapy treatment prior to plasma collection. Reported p-values arecomputed using two-tailed Wilcoxon-Mann-Whitney test or Pearsoncorrelation.

FIG. 4A-FIG. 4D show association of plasma tumor content and plasmaprostate cancer driver genes with overall survival and progression-freesurvival. FIGS. 4A and 4B show overall survival and radiographicprogression-free survival for high versus low tumor content (TC)estimations (FIG. 4A) and for AR CN neutral versus AR focal gain (FIG.4B); univariate analysis results only and multivariate (controlling forTC) analysis are shown in the inset. FIGS. 4C and 4D show the overallsurvival for lesions in TP53 and/or RB1 (FIG. 4C) and for BRCA1, BRCA2,ATM (FIG. 4D); univariate and multivariate analysis are shown in theinsets. All analyses are reported for the entire cohort (left panel),for CRPC-Adeno (center panel) and for CRPC-NE (right panel). Univariateoverall survival and progression-free survival analyses were performedusing the Kaplan-Meier estimator (log-rank test). Multivariate overalland progression-free survival analyses were performed using aproportional hazard model with stepwise model selection by Akaikeinformation criterion using forward and backward directions.

FIG. 5 shows the landscape of somatic aberrations in plasma and tissuesamples across CRPC-Adeno (top panel), CRPC-NE (middle panel), and HNPC(bottom panel) classes. Grey cells in oncoprints represent eitherwild-type or absence of available call. Reported gene aberrationfractions are computed excluding all samples for which no calls areavailable neither for SNVs nor for SCNAs.

FIG. 6A-FIG. 6D show similarity of somatic aberration profiles acrossplasma and metastatic tumor tissue samples. FIG. 6A shows intra-patientsomatic copy number aberrations (SCNAs, left, Loss and Gain) and singlenucleotide variants (SNVs, right) similarity across metastatic biopsiesstratified by patient's tumor class at plasma collection (Table 10).FIG. 6B shows inter- and intra-patient measures of SCNAs similarity persite and across sites of metastasis. FIG. 6C shows intra-patient lossand gain SCNAs similarities (left) and SNVs (right) similarities(fraction of SNVs in plasma detected also in tissues and fraction ofSNVs in tissues detected also in plasma) across tissue and plasmasamples stratified by patient's tumor class at plasma collection. Onlysamples of patients with estimated ctDNA >10% are considered. The sametrends are also obtained with more restrictive filter on TC>50%. FIG. 6Dshows SCNAs similarity among plasma and tumor tissue samples of patientWCMO (left); Private and shared SNVs comparison between WCMO plasma andselected tumor tissue samples. Reported p-values are computed usingtwo-tailed Wilcoxon-Mann-Whitney test.

FIG. 7 shows clonality divergence as assessed for tissue and plasmastudy cohort samples. Distribution of the clonality diverge index intumor tissue and plasma samples across patients classified as CRPC-Adenoand CRPC-NE at plasma collection. Reported p-values are computed usingtwo-tailed Wilcoxon-Mann-Whitney test.

FIG. 8A-FIG. 8B show allele-specific copy number quantification ofmatched plasma and tumor tissue samples. FIG. 8A shows patient datademonstrating almost identical genomic status between a metastasis and aplasma sample, indicating high homogeneity among all patient'smetastases. The lymph node metastasis of patient WCM198 and the plasmasample were collected at 4 days apart. Polygons include cancer geneswith same allele-specific copy number; red dots correspond to reportedgene names. FIG. 8B shows patient data with heterogeneous profiles.Patient WCM183 liver metastasis was obtained 13 days prior to the plasmasample. Blue indicates genes with different allele-specific copy number.

FIG. 9A-FIG. 9B show patient data. FIG. 9A shows patient datademonstrating almost identical genomic status between a metastasis and aplasma sample, indicating high homogeneity among all patients'metastases. Polygons include cancer genes with same allele-specific copynumber. FIG. 9B shows patient data with heterogeneous profiles. Blueindicates genes with different allele-specific copy number.

FIG. 10A-FIG. 10B show heterogeneity of somatic aberration profiles inmultiple plasma and tumor tissue sample series. FIG. 10A showssomatic-copy number aberrations (SCNAs) and single nucleotide variants(SCNAs) similarities among plasma and tumor tissue samples of patientWCM161. Samples are ordered by date of collection with date differencesreported in days. SNVs similarity is an asymmetric measure based on setinclusion and the complete matrix is shown. SCNAs similarity is insteada symmetric measure based on the Jaccard coefficient and henceinformation is shown without redundancy. FIG. 10B shows results of agenomic analysis of WCM185 and WMC14 multi-sample series. The panelreports: allele-specific copy number of a selection of advanced prostatecancer driver genes (HomDel=homozygous deletion, HetDel=heterozygousdeletion, CNNL=copy number neutral loss, Del|Gain=events defined by lossof one allele and gain of the other allele); AR L702H and AR T878A SNVs(determined by pileup analysis); tumor content estimations; ploidy stateestimation; normalized SNVs load, with values representing the ratiobetween the sample's SNVs number and the sample type (plasma/tumortissue) median SNVs number. Samples are ordered by date of collection(intervals shown).

FIG. 11 shows SCNAs having similarity among plasma and tumor tissuesamples of patients with multiple tissue biopsies and plasma tumorcontent greater or equal than 10%.

FIG. 12A-FIG. 12E show that differential methylation signal is detectedin circulation of patients. FIG. 12A shows a PAMES purity estimation ofplasma WGBS plasma and PBMC samples. Top 10 most informativehypermethylated CpG Island were used. FIG. 12B shows results of a Ward'shierarchical clustering of 25 samples using ‘1—Pearson's correlationcoefficient’ as distance measure. The annotation tracks includeinformation on sample tumor purity and on the site of the relativesequenced tissue biopsy for all tissue samples and on the presence orabsence of lymph node, bone or visceral metastases in the correspondingpatient for the plasma samples. FIG. 12C shows results of evaluation ofdifferentially methylated regions (DMRs) concordance in matched plasmaand tissue samples. Two distinct DMR sets were nominated applyingRocker-Meth algorithm on tissue samples and single sample z-scores werecomputed for each DMR. A comparison between values detected in ctDNA andtissue biopsy and results are reported for three representativepatients: WCM90, CRPC-Adeno; WCMO, CRPC-NE; WCM119, CRPC-Adeno withradiographic progression on enzalutamide, PSA 3.5 and elevated serumNSE. Color density is proportional to point density to the power of ¼ toimprove visualization. First-order linear regression R squared isreported. FIG. 12D shows a comparison of average absolute z-score basedon CRPC-NE|CRPC-Adeno DMR in plasma samples from this cohort and from aset of patients treated with abiraterone acetate reported in Gordeviciuset al. (2018) Clin Cancer Res 24:3317-3324. To maximize thecompatibility of clinical history and disease stage, onlyend-of-treatment samples with an estimated tumor content greater than10% were included. Significance was assessed using two-tailed unpairedWilcoxon-Mann-Whitney test without continuity correction. FIG. 12E showsplotted NEPC feature scores as assessed in plasma data of CRPC-Adeno andCRPC-NE patients.

FIG. 13A-FIG. 13E show patient data. FIG. 13A shows a genome-widecomparison of methylation patterns in CRPC-NE and CRPC-Adeno as measuredin plasma and in tissue samples. Differences averaged betas are plotted.Red line shows interpolation by the lowess function; R is the Pearson'scorrelation coefficient. FIG. 13B shows tumor fraction estimates frompatient circulating material by a scatter plot of the tumor purityestimates by a methylation based (PAMES on WGBS data) versus a genomicbased approach (CLONET on WES). Colors refer to the pathologyclassification. R is the Pearson's correlation coefficient. FIG. 13Cshows beta values in plasma and tissue samples across portions of fourgenes of interest. ASXL3 and SPDEF were included in the NEPC classifierfrom Beltran and Prandi et al. CDH2 and INSM1 are associated with sitesused in the NEPC feature score. Lines are fitted to CRPC-Adeno (pink)and CRPC-NE (purple) samples medians of single CpG sites using loessfunction. Plasma CpG sites were filtered keeping only those presentingat least 2 measurements for each class. FIG. 13D shows a comparison ofaverage absolute z-score measured in tissue samples (Beltran et al.(2016) Nat Med 22:298-305) and plasma samples (this cohort) for the twotarget DMR sets reported in FIG. 14 . P-values are calculated withunpaired two-sided Wilcoxon-Mann-Whitney test. FIG. 13E shows box plotsof the distribution of beta values in ctDNA samples for sites identifiedas differentially methylated in CRPC-NE vs CRPC-Adeno in tissue samples(hypo: AUC<0.2; hyper: AUC>0.8). P-value are calculated byWilcoxon-Mann-Whitney test.

FIG. 14 shows a proposed model of prostate cancer progression towardsCRPC-NE. Metastatic prostate cancer lesions harbor shared alterationsoften traceable back to a primary tumor clone, supporting a monoclonalorigin of metastatic prostate cancer. Tumors acquire alterations withdisease progression and treatment resistance, and these alterations canbe subclonal. Polyclonal spread in later stages further leads tointra-patient heterogeneity. During the transition towards CRPC-NE,there is likely selection of a dominant clone that persists anddominates. DNA methylation profiles dramatically shift with CRPC-NE.

FIG. 15A-FIG. 15E show results of input DNA titration experiments forwhole exome sequencing and deduplication analysis. FIG. 15A shows copynumber profiles correlation for a set of cancer genes assessed fromprocessed sequencing data from a series of titration experiment. Thesample was selected based on tumor volume/tumor content. Data are shownfrom libraries built starting from 50 ng, 20 ng, 10 ng, or 5 ng, andprocessed with or without a filter to remove read duplicates (DR). FIG.15B shows a genome-wide view of copy number profiles of previous data isshown together with matched tumor tissue biopsy data. FIG. 15C shows thepercentiles of read duplicates distribution across plasma and germlinesamples and across different coverage intervals.

FIG. 15D shows distributions of germline and plasma mean coverage acrossad hoc de-duplication strategies. FIG. 15E shows a comparison of copynumber profiles for a set of cancer genes obtained from sequencing dataincluding read duplicates and upon deduplication using differentstrategies. See working example 1 herein. (SE=single end sequencingprotocol, PE=paired end sequencing protocol, DR=inclusion of readduplicates).

DETAILED DESCRIPTION OF THE INVENTION

It has been determined herein that a targeted set combining genomic(e.g., TP53, RB1, CPLD, AR) and epigenomic (e.g., hypo- andhyper-methylation sites) alterations applied to ctDNA is advantageouslyuseful for identifying patients with CRPC-NE. These CRPC-NE specificfeatures were identified by studying whole exome sequencing and wholegenome bisulfite sequencing of cell free DNA (cfDNA) and of matchedmetastatic tumor biopsies from patients with metastatic prostateadenocarcinoma and CRPC-NE. It was also found that there wassignificantly higher concordance between cfDNA and biopsy tissue genomicalterations in CRPC-NE patients compared to castration resistantadenocarcinoma, supporting greater intra-individual genomic consistencyacross metastases. Allele-specific copy number and serial samplinganalyses allowed for the detection and tracking of clonal and subclonaltumor cell populations. In addition, cfDNA methylation was indicative ofcirculating tumor content fraction, reflective of methylation patternsobserved in biopsy tissues, and was capable of detectingCRPC-NE-associated epigenetic changes (e.g., hypermethylation of ASXL3and SPDEF; hypomethylation of INSM1 and CDH2).

A circulating biomarker for CRPC-NE provides a technical improvement anduseful advantage for the avoidance of invasive biopsy for patients,which is the current standard for CRPC-NE diagnosis. Furthermore, sincethere is a spectrum of histologies even within CRPC-NE, and as patientsprogress from adenocarcinoma to CRPC-NE, with mixedadenocarcinoma-neuroendocrine morphologies and hybrid tumors withoverlapping features sometimes observed, identifying molecular featuresfurther provides a technical improvement and useful advantage ininformation that is complementary to that of a tumor biopsy.Non-invasive detection of molecular features of CRPC-NE can thereforelead to a improved and refined sub-classification and detect features inpatients at high risk for transformation even without CRPC-NE histology,paving the way for early intervention treatment strategies.

Accordingly, the present invention provides methods of diagnosing,prognosing, and monitoring CRPC-NE involving detecting the present orabsence of the genomic and/or epigenomic alterations identified forCRPC-NE, and methods of treating CRPC-NE by modulating these genomicand/or epigenomic features.

I. Definitions

The articles “a” and “an” are used herein to refer to one or to morethan one (i.e. to at least one) of the grammatical object of thearticle. By way of example, “an element” means one element or more thanone element.

The term “altered amount” or “altered level” refers to increased ordecreased copy number (e.g., germline and/or somatic) of a biomarkernucleic acid, e.g., increased or decreased expression level in a cancersample, as compared to the expression level or copy number of thebiomarker nucleic acid in a control sample. The term “altered amount” ofa biomarker also includes an increased or decreased protein level of abiomarker protein in a sample, e.g., a cancer sample, as compared to thecorresponding protein level in a normal, control sample. Furthermore, analtered amount of a biomarker protein may be determined by detectingposttranslational modification such as methylation status of the marker,which may affect the expression or activity of the biomarker protein.

The amount of a biomarker in a subject is “significantly” higher orlower than the normal amount of the biomarker, if the amount of thebiomarker is greater or less, respectively, than the normal level by anamount greater than the standard error of the assay employed to assessamount, and preferably at least 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%,90%, 100%, 150%, 200%, 300%, 350%, 400%, 500%, 600%, 700%, 800%, 900%,1000% or than that amount. Alternately, the amount of the biomarker inthe subject can be considered “significantly” higher or lower than thenormal amount if the amount is at least about two, and preferably atleast about three, four, or five times, higher or lower, respectively,than the normal amount of the biomarker. Such “significance” can also beapplied to any other measured parameter described herein, such as forexpression, inhibition, cytotoxicity, cell growth, and the like.

The term “altered level of expression” of a biomarker refers to anexpression level or copy number of the biomarker in a test sample, e.g.,a sample derived from a patient suffering from cancer, that is greateror less than the standard error of the assay employed to assessexpression or copy number, and is preferably at least twice, and morepreferably three, four, five or ten or more times the expression levelor copy number of the biomarker in a control sample (e.g., sample from ahealthy subjects not having the associated disease) and preferably, theaverage expression level or copy number of the biomarker in severalcontrol samples. The altered level of expression is greater or less thanthe standard error of the assay employed to assess expression or copynumber, and is preferably at least 10%, 20%, 30%, 40%, 50%, 60%, 70%,80%, 90%, 100%, 150%, 200%, 300%, 350%, 400%, 500%, 600%, 700%, 800%,900%, 1000% or more times the expression level or copy number of thebiomarker in a control sample (e.g., sample from a healthy subjects nothaving the associated disease) and preferably, the average expressionlevel or copy number of the biomarker in several control samples. Insome embodiments, the level of the biomarker refers to the level of thebiomarker itself, the level of a modified biomarker (e.g.,phosphorylated biomarker), or to the level of a biomarker relative toanother measured variable, such as a control (e.g., phosphorylatedbiomarker relative to an unphosphorylated biomarker).

The term “altered activity” of a biomarker refers to an activity of thebiomarker which is increased or decreased in a disease state, e.g., in acancer sample, as compared to the activity of the biomarker in a normal,control sample. Altered activity of the biomarker may be the result of,for example, altered expression of the biomarker, altered protein levelof the biomarker, altered structure of the biomarker, or, e.g., analtered interaction with other proteins involved in the same ordifferent pathway as the biomarker or altered interaction withtranscriptional activators or inhibitors.

The term “altered structure” of a biomarker refers to the presence ofmutations or allelic variants within a biomarker nucleic acid orprotein, e.g., mutations which affect expression or activity of thebiomarker nucleic acid or protein, as compared to the normal orwild-type gene or protein. For example, mutations include, but are notlimited to substitutions, deletions, or addition mutations. Mutationsmay be present in the coding or non-coding region of the biomarkernucleic acid.

Unless otherwise specified here within, the terms “antibody” and“antibodies” refers to antigen-binding portions adaptable to beexpressed within cells as “intracellular antibodies.” (Chen et al.(1994) Human Gene Ther. 5:595-601). Methods are well-known in the artfor adapting antibodies to target (e.g., inhibit) intracellularmoieties, such as the use of single-chain antibodies (scFvs),modification of immunoglobulin VL domains for hyperstability,modification of antibodies to resist the reducing intracellularenvironment, generating fusion proteins that increase intracellularstability and/or modulate intracellular localization, and the like.Intracellular antibodies can also be introduced and expressed in one ormore cells, tissues or organs of a multicellular organism, for examplefor prophylactic and/or therapeutic purposes (e.g., as a gene therapy)(see, at least PCT Publs. WO 08/020079, WO 94/02610, WO 95/22618, and WO03/014960; U.S. Pat. No. 7,004,940; Cattaneo and Biocca (1997)Intracellular Antibodies: Development and Applications (Landes andSpringer-Verlag publs.); Kontermann (2004) Methods 34:163-170; Cohen etal. (1998) Oncogene 17:2445-2456; Auf der Maur et al. (2001) FEBS Lett.508:407-412; Shaki-Loewenstein et al. (2005) J. Immunol. Meth.303:19-39).

Antibodies may be polyclonal or monoclonal; xenogeneic, allogeneic, orsyngeneic; or modified forms thereof (e.g. humanized, chimeric, etc.).Antibodies may also be fully human. Preferably, antibodies of thepresent invention bind specifically or substantially specifically to abiomarker polypeptide or fragment thereof. The terms “monoclonalantibodies” and “monoclonal antibody composition”, as used herein, referto a population of antibody polypeptides that contain only one speciesof an antigen binding site capable of immunoreacting with a particularepitope of an antigen, whereas the term “polyclonal antibodies” and“polyclonal antibody composition” refer to a population of antibodypolypeptides that contain multiple species of antigen binding sitescapable of interacting with a particular antigen. A monoclonal antibodycomposition typically displays a single binding affinity for aparticular antigen with which it immunoreacts.

Antibodies may also be “humanized”, which is intended to includeantibodies made by a non-human cell having variable and constant regionswhich have been altered to more closely resemble antibodies that wouldbe made by a human cell. For example, by altering the non-human antibodyamino acid sequence to incorporate amino acids found in human germlineimmunoglobulin sequences. The humanized antibodies of the presentinvention may include amino acid residues not encoded by human germlineimmunoglobulin sequences (e.g., mutations introduced by random orsite-specific mutagenesis in vitro or by somatic mutation in vivo), forexample in the CDRs. The term “humanized antibody”, as used herein, alsoincludes antibodies in which CDR sequences derived from the germline ofanother mammalian species, such as a mouse, have been grafted onto humanframework sequences.

The term “assigned score” refers to the numerical value designated foreach of the biomarkers after being measured in a patient sample. Theassigned score correlates to the absence, presence or inferred amount ofthe biomarker in the sample. The assigned score can be generatedmanually (e.g., by visual inspection) or with the aid of instrumentationfor image acquisition and analysis. In certain embodiments, the assignedscore is determined by a qualitative assessment, for example, detectionof a fluorescent readout on a graded scale, or quantitative assessment.In one embodiment, an “aggregate score,” which refers to the combinationof assigned scores from a plurality of measured biomarkers, isdetermined. In one embodiment the aggregate score is a summation ofassigned scores. In another embodiment, combination of assigned scoresinvolves performing mathematical operations on the assigned scoresbefore combining them into an aggregate score. In certain, embodiments,the aggregate score is also referred to herein as the “predictivescore.”

The term “biomarker” refers to a measurable entity of the presentinvention that has been determined to assess whether a subject isafflicted with castration-resistant neuroendocrine prosate cancer(CRPC-NE) or at risk for developing CRPC-NE. Biomarkers can include,without limitation, nucleic acids and proteins, including those shown inthe Tables, the Examples, the Figures, and otherwise described herein.As described herein, any relevant characteristic of a biomarker can beused, such as the copy number, amount, activity, location, modification(e.g., phosphorylation), genomic alterations (e.g., deletion, gain, ormutation), epigenetic alterations (e.g., hypermethylation orhypomethylation) and the like.

A “blocking” antibody or an antibody “antagonist” is one which inhibitsor reduces at least one biological activity of the antigen(s) it binds.In certain embodiments, the blocking antibodies or antagonist antibodiesor fragments thereof described herein substantially or completelyinhibit a given biological activity of the antigen(s).

The term “body fluid” refers to fluids that are excreted or secretedfrom the body as well as fluids that are normally not (e.g. amnioticfluid, aqueous humor, bile, blood and blood plasma, cerebrospinal fluid,cerumen and earwax, cowper's fluid or pre-ejaculatory fluid, chyle,chyme, stool, female ejaculate, interstitial fluid, intracellular fluid,lymph, menses, breast milk, mucus, pleural fluid, pus, saliva, sebum,semen, serum, sweat, synovial fluid, tears, urine, vaginal lubrication,vitreous humor, vomit).

The terms “cancer” or “tumor” or “hyperproliferative” refer to thepresence of cells possessing characteristics typical of cancer-causingcells, such as uncontrolled proliferation, immortality, metastaticpotential, rapid growth and proliferation rate, and certaincharacteristic morphological features. Unless otherwise stated, theterms include metaplasias.

Cancer cells are often in the form of a tumor, but such cells may existalone within an animal, or may be a non-tumorigenic cancer cell, such asa leukemia cell. As used herein, the term “cancer” includes premalignantas well as malignant cancers. Cancers include, but are not limited to, Bcell cancer, e.g., multiple myeloma, Waldenström's macroglobulinemia,the heavy chain diseases, such as, for example, alpha chain disease,gamma chain disease, and mu chain disease, benign monoclonal gammopathy,and immunocytic amyloidosis, melanomas, breast cancer, lung cancer,bronchus cancer, colorectal cancer, prostate cancer, pancreatic cancer,stomach cancer, ovarian cancer, urinary bladder cancer, brain or centralnervous system cancer, peripheral nervous system cancer, esophagealcancer, cervical cancer, uterine or endometrial cancer, cancer of theoral cavity or pharynx, liver cancer, kidney cancer, testicular cancer,biliary tract cancer, small bowel or appendix cancer, salivary glandcancer, thyroid gland cancer, adrenal gland cancer, osteosarcoma,chondrosarcoma, cancer of hematologic tissues, and the like. Othernon-limiting examples of types of cancers applicable to the methodsencompassed by the present invention include human sarcomas andcarcinomas, e.g., fibrosarcoma, myxosarcoma, liposarcoma,chondrosarcoma, osteogenic sarcoma, chordoma, angiosarcoma,endotheliosarcoma, lymphangiosarcoma, lymphangioendotheliosarcoma,synovioma, mesothelioma, Ewing's tumor, leiomyosarcoma,rhabdomyosarcoma, colon carcinoma, colorectal cancer, pancreatic cancer,breast cancer, ovarian cancer, prostate cancer, squamous cell carcinoma,basal cell carcinoma, adenocarcinoma, sweat gland carcinoma, sebaceousgland carcinoma, papillary carcinoma, papillary adenocarcinomas,cystadenocarcinoma, medullary carcinoma, bronchogenic carcinoma, renalcell carcinoma, hepatoma, bile duct carcinoma, liver cancer,choriocarcinoma, seminoma, embryonal carcinoma, Wilms' tumor, cervicalcancer, bone cancer, brain tumor, testicular cancer, lung carcinoma,small cell lung carcinoma, bladder carcinoma, epithelial carcinoma,glioma, astrocytoma, medulloblastoma, craniopharyngioma, ependymoma,pinealoma, hemangioblastoma, acoustic neuroma, oligodendroglioma,meningioma, melanoma, neuroblastoma, retinoblastoma; leukemias, e.g.,acute lymphocytic leukemia and acute myelocytic leukemia (myeloblastic,promyelocytic, myelomonocytic, monocytic and erythroleukemia); chronicleukemia (chronic myelocytic (granulocytic) leukemia and chroniclymphocytic leukemia); and polycythemia vera, lymphoma (Hodgkin'sdisease and non-Hodgkin's disease), multiple myeloma, Waldenstrom'smacroglobulinemia, and heavy chain disease. In some embodiments, cancersare epithlelial in nature and include but are not limited to, bladdercancer, breast cancer, cervical cancer, colon cancer, gynecologiccancers, renal cancer, laryngeal cancer, lung cancer, oral cancer, headand neck cancer, ovarian cancer, pancreatic cancer, prostate cancer, orskin cancer. In other embodiments, the cancer is breast cancer, prostatecancer, lung cancer, or colon cancer. In still other embodiments, theepithelial cancer is non-small-cell lung cancer, nonpapillary renal cellcarcinoma, cervical carcinoma, ovarian carcinoma (e.g., serous ovariancarcinoma), or breast carcinoma. The epithelial cancers may becharacterized in various other ways including, but not limited to,serous, endometrioid, mucinous, clear cell, Brenner, orundifferentiated.

In certain embodiments, the cancer encompasses prostate cancer. Prostatecancer (Pca) is cancer that occurs in the prostate. Prostate cancer isone of the most common types of cancer in men. Usually prostate cancergrows slowly and is initially confined to the prostate gland, where itmay not cause serious harm. However, other types are aggressive and canspread quickly.

Prostate cancer is typically diagnosed with a digital rectal exam and/orprostate specific antigen (PSA) screening. An elevated serum PSA levelcan indicate the presence of prostate cancer. PSA is used as a markerfor prostate cancer because it is secreted only by prostate cells. WhenPSA or digital tests indicate a strong likelihood that cancer ispresent, a transrectal ultrasound (TRUS) is used to map the prostate andshow any suspicious areas. Biopsies of various sectors of the prostateare used to determine if prostate cancer is present.

Treatment options depend on the stage of the cancer. Men with a 10-yearlife expectancy or less who have a low Gleason number and whose tumorhas not spread beyond the prostate are often treated with watchfulwaiting (no treatment). Treatment options for more aggressive cancersinclude surgical treatments, such as radical prostatectomy (RP) in whichthe prostate is completely removed (with or without nerve sparingtechniques), and radiation, applied through an external beam thatdirects the dose to the prostate from outside the body or via low-doseradioactive seeds that are implanted within the prostate to kill cancercells locally. Anti-androgen hormone therapy may also be used, alone orin conjunction with surgery or radiation. Hormone therapy may useluteinizing hormone-releasing hormones (LH-RH) analogs, which block thepituitary from producing hormones that stimulate testosteroneproduction. Patients may need to have injections of LH-RH analogs forthe rest of their lives. While surgical and hormonal treatments areoften effective for localized prostate cancer, advanced disease remainsessentially incurable. Androgen ablation is the most common therapy foradvanced prostate cancer, leading to massive apoptosis ofandrogen-dependent malignant cells and temporary tumor regression.However, the tumor may reemerge with a vengeance and can proliferateindependent of androgen signals.

“Castrate-resistant prostate cancer (CRPC)” is defined by diseaseprogression despite androgen-deprivation therapy (ADT) and may presentas one or any combination of a continuous rise in serum levels ofprostate-specific antigen (PSA), progression of pre-existing disease, orappearance of new metastases. Advanced prostate cancer has been known bya number of names over the years, including hormone-resistant prostatecancer (HRPC) and androgen-insensitive prostate cancer. Most recently,the terms “castrate-resistant” or “castration-recurrent” prostate cancerwere introduced with the realization that intracrine and paracrineandrogen production plays a significant role in the resistance ofprostate cancer cells to testosterone-suppression therapy. In theirsecond publication, the Prostate Cancer Working Group (PCWG2) definedCRPC as a continuum on the basis of whether metastases are detectable(clinically or by imaging) and whether serum testosterone is in thecastrate range because of a surgical orchiectomy or medical therapy(Scher et al. (2008) J Clin Oncol. 26:1148-1159). The resultingclinical-states model can be used to classify patients. Within therising PSA states (castrate and non-castrate), no detectable (measurableor non-measurable) disease has ever been found. Alternatively, in theclinical metastases states (castrate and non-castrate), disease has tohave been detectable at some point in the past, regardless of whether itis currently detectable. Castrate-resistant prostate cancer presents aspectrum of disease ranging from rising PSA levels without metastases orsymptoms and despite adt, to metastases and significant debilitationfrom cancer symptoms.

Prognosis is associated with several factors, including performancestatus, presence of bone pain, extent of disease on bone scan, and serumlevels of alkaline phosphatase. Bone metastases occur in 90% of men withCRPC and can produce significant morbidity, including pain, pathologicfractures, spinal cord compression, and bone marrow failure.Paraneoplastic effects are also common, including anemia, weight loss,fatigue, hypercoagulability, and increased susceptibility to infection.

The mainstay of therapy for patients with metastatic spread, includingcastration-resistant prosate cancer, is hormonal therapy that targetsthe AR. For example, enzalutamid and abriraterone are potent AR-targetedtherapies approved for the treatment of men with CRPC. Other treatmentmethods include, but are not limited to, other alternative hormonetherapies, taxane chemotherapy (e.g., docetaxel, cabazitaxel),bone-targeting radiopharmaceuticals (e.g., radium-223) and immunotherapy(e.g., sipuleucel-T), etc., with the goals of prolonging survival,minimizing complications, and maintaining quality of life.

Castration-resistant prostate cancer is histologically characterized asprostate adenocarcinomas (CRPC-Adeno) and neuroendocrine prosate cancer(CRPC-NE). Histologically, NEPC is characterized by the presence ofsmall, round, blue neuroendocrine carcinoma cells, which do not expressandrogen receptor or secrete prostate specific antigen (PSA), butusually express neuroendocrine markers such as chromogranin A,synaptophysin, and neuron-specific enolase.

Neuroendocrine prostate cancer (NEPC) is an aggressive subtype ofprostate cancer that can arise de novo, but much more commonly arisesafter hormonal therapy for prostate adenocarcinoma (PCA) (PALMGREN etal., Semin Oncol, 34:22-9 (2007)). It is known that the amount ofneuroendocrine differentiation increases with disease progression andcorrelates with patient exposure to long-term androgen deprivationtherapy. NEPC reportedly differs histologically from PCA, and ischaracterized by the presence of small round blue neuroendocrine cells,which do not express androgen receptor (AR) or secrete prostate specificantigen (PSA), but usually express neureondocrine markers such aschromogranin A, synaptophysin, and neuron specific enolase (NSE)(Wang etal. (2008) Am Surg Pathol. 32:65-71). The prostate cancer specificTMPRSS2-ERG gene rearrangement (Tomlins et al. (2005) Science310:644-648) has been reported in approximately 50% of NEPC (Lotan etal. (2011) Mod Pathol.), similar to the frequency in PCA (Mosquera etal. (2009) Clin Cancer Res. 15:4706-4711). This suggests clonal originof NEPC from PCA and distinguishes NEPC from small carcinomas of otherprimary sites (Scheble et al. (2010) Mod Pathol. 23:1061-1067). The poormolecular characterization of NEPC accounts in part for the lack ofdisease specific therapeutics.

The term “coding region” refers to regions of a nucleotide sequencecomprising codons which are translated into amino acid residues, whereasthe term “noncoding region” refers to regions of a nucleotide sequencethat are not translated into amino acids (e.g., 5′ and 3′ untranslatedregions).

The term “complementary” refers to the broad concept of sequencecomplementarity between regions of two nucleic acid strands or betweentwo regions of the same nucleic acid strand. It is known that an adenineresidue of a first nucleic acid region is capable of forming specifichydrogen bonds (“base pairing”) with a residue of a second nucleic acidregion which is antiparallel to the first region if the residue isthymine or uracil. Similarly, it is known that a cytosine residue of afirst nucleic acid strand is capable of base pairing with a residue of asecond nucleic acid strand which is antiparallel to the first strand ifthe residue is guanine. A first region of a nucleic acid iscomplementary to a second region of the same or a different nucleic acidif, when the two regions are arranged in an antiparallel fashion, atleast one nucleotide residue of the first region is capable of basepairing with a residue of the second region. Preferably, the firstregion comprises a first portion and the second region comprises asecond portion, whereby, when the first and second portions are arrangedin an antiparallel fashion, at least about 50%, and preferably at leastabout 75%, at least about 90%, or at least about 95% of the nucleotideresidues of the first portion are capable of base pairing withnucleotide residues in the second portion. More preferably, allnucleotide residues of the first portion are capable of base pairingwith nucleotide residues in the second portion.

The term “control” refers to any reference standard suitable to providea comparison to the expression products in the test sample. In oneembodiment, the control comprises obtaining a “control sample” fromwhich expression product levels are detected and compared to theexpression product levels from the test sample. Such a control samplemay comprise any suitable sample, including but not limited to a samplefrom a control cancer patient (can be stored sample or previous samplemeasurement) with a known outcome; normal tissue or cells isolated froma subject, such as a normal patient or the cancer patient, culturedprimary cells/tissues isolated from a subject such as a normal subjector the cancer patient, adjacent normal cells/tissues obtained from thesame organ or body location of the cancer patient, a tissue or cellsample isolated from a normal subject, or a primary cells/tissuesobtained from a depository. In another preferred embodiment, the controlmay comprise a reference standard expression product level from anysuitable source, including but not limited to housekeeping genes, anexpression product level range from normal tissue (or other previouslyanalyzed control sample), a previously determined expression productlevel range within a test sample from a group of patients, or a set ofpatients with a certain outcome (for example, survival for one, two,three, four years, etc.) or receiving a certain treatment (for example,standard of care cancer therapy). It will be understood by those ofskill in the art that such control samples and reference standardexpression product levels can be used in combination as controls in themethods of the present invention. In one embodiment, the control maycomprise normal or non-cancerous cell/tissue sample. In anotherpreferred embodiment, the control may comprise an expression level for aset of patients, such as a set of cancer patients, or for a set ofcancer patients receiving a certain treatment, or for a set of patientswith one outcome versus another outcome. In the former case, thespecific expression product level of each patient can be assigned to apercentile level of expression, or expressed as either higher or lowerthan the mean or average of the reference standard expression level. Inanother preferred embodiment, the control may comprise normal cells,cells from patients treated with combination chemotherapy, and cellsfrom patients having benign cancer. In another embodiment, the controlmay also comprise a measured value for example, average level ofexpression of a particular gene in a population compared to the level ofexpression of a housekeeping gene in the same population. Such apopulation may comprise normal subjects, cancer patients who have notundergone any treatment (i.e., treatment naive), cancer patientsundergoing standard of care therapy, or patients having benign cancer.In another preferred embodiment, the control comprises a ratiotransformation of expression product levels, including but not limitedto determining a ratio of expression product levels of two genes in thetest sample and comparing it to any suitable ratio of the same two genesin a reference standard; determining expression product levels of thetwo or more genes in the test sample and determining a difference inexpression product levels in any suitable control; and determiningexpression product levels of the two or more genes in the test sample,normalizing their expression to expression of housekeeping genes in thetest sample, and comparing to any suitable control. In particularlypreferred embodiments, the control comprises a control sample which isof the same lineage and/or type as the test sample. In anotherembodiment, the control may comprise expression product levels groupedas percentiles within or based on a set of patient samples, such as allpatients with cancer. In one embodiment a control expression productlevel is established wherein higher or lower levels of expressionproduct relative to, for instance, a particular percentile, are used asthe basis for predicting outcome. In another preferred embodiment, acontrol expression product level is established using expression productlevels from cancer control patients with a known outcome, and theexpression product levels from the test sample are compared to thecontrol expression product level as the basis for predicting outcome. Asdemonstrated by the data below, the methods of the present invention arenot limited to use of a specific cut-point in comparing the level ofexpression product in the test sample to the control.

The “copy number” of a biomarker nucleic acid refers to the number ofDNA sequences in a cell (e.g., germline and/or somatic) encoding aparticular gene product. Generally, for a given gene, a mammal has twocopies of each gene. The copy number can be increased, however, by geneamplification or duplication, or reduced by deletion. For example,germline copy number changes include changes at one or more genomicloci, wherein said one or more genomic loci are not accounted for by thenumber of copies in the normal complement of germline copies in acontrol (e.g., the normal copy number in germline DNA for the samespecies as that from which the specific germline DNA and correspondingcopy number were determined). Somatic copy number changes includechanges at one or more genomic loci, wherein said one or more genomicloci are not accounted for by the number of copies in germline DNA of acontrol (e.g., copy number in germline DNA for the same subject as thatfrom which the somatic DNA and corresponding copy number weredetermined).

The “normal” copy number (e.g., germline and/or somatic) of a biomarkernucleic acid or “normal” level of expression of a biomarker nucleic acidor protein is the activity/level of expression or copy number in abiological sample, e.g., a sample containing tissue, whole blood, serum,plasma, buccal scrape, saliva, cerebrospinal fluid, urine, stool, andbone marrow, from a subject, e.g., a human, not afflicted with cancer,or from a corresponding non-cancerous tissue in the same subject who hascancer.

As used herein, the term “costimulate” with reference to activatedimmune cells includes the ability of a costimulatory molecule to providea second, non-activating receptor mediated signal (a “costimulatorysignal”) that induces proliferation or effector function. For example, acostimulatory signal can result in cytokine secretion, e.g., in a T cellthat has received a T cell-receptor-mediated signal. Immune cells thathave received a cell-receptor mediated signal, e.g., via an activatingreceptor are referred to herein as “activated immune cells.”

The term “determining a suitable treatment regimen for the subject” istaken to mean the determination of a treatment regimen (i.e., a singletherapy or a combination of different therapies that are used for theprevention and/or treatment of the cancer in the subject) for a subjectthat is started, modified and/or ended based or essentially based or atleast partially based on the results of the analysis according to thepresent invention. One example is starting an adjuvant therapy aftersurgery whose purpose is to decrease the risk of recurrence, anotherwould be to modify the dosage of a particular chemotherapy. Thedetermination can, in addition to the results of the analysis accordingto the present invention, be based on personal characteristics of thesubject to be treated. In most cases, the actual determination of thesuitable treatment regimen for the subject will be performed by theattending physician or doctor.

The term “diagnosing cancer” includes the use of the methods, systems,and code of the present invention to determine the presence or absenceof a cancer or subtype thereof in an individual. The term also includesmethods, systems, and code for assessing the level of disease activityin an individual.

A molecule is “fixed” or “affixed” to a substrate if it is covalently ornon-covalently associated with the substrate such that the substrate canbe rinsed with a fluid (e.g. standard saline citrate, pH 7.4) without asubstantial fraction of the molecule dissociating from the substrate.

The term “expression signature” or “signature” refers to a group of oneor more coordinately expressed biomarkers related to a measuredphenotype. For example, the genes, proteins, metabolites, and the likemaking up this signature may be expressed in a specific cell lineage,stage of differentiation, or during a particular biological response.The biomarkers can reflect biological aspects of the tumors in whichthey are expressed, such as the cell of origin of the cancer, the natureof the non-malignant cells in the biopsy, and the oncogenic mechanismsresponsible for the cancer. Expression data and gene expression levelscan be stored on computer readable media, e.g., the computer readablemedium used in conjunction with a microarray or chip reading device.Such expression data can be manipulated to generate expressionsignatures.

“Homologous” as used herein, refers to nucleotide sequence similaritybetween two regions of the same nucleic acid strand or between regionsof two different nucleic acid strands. When a nucleotide residueposition in both regions is occupied by the same nucleotide residue,then the regions are homologous at that position. A first region ishomologous to a second region if at least one nucleotide residueposition of each region is occupied by the same residue. Homologybetween two regions is expressed in terms of the proportion ofnucleotide residue positions of the two regions that are occupied by thesame nucleotide residue. By way of example, a region having thenucleotide sequence 5′-ATTGCC-3′ and a region having the nucleotidesequence 5′-TATGGC-3′ share 50% homology. Preferably, the first regioncomprises a first portion and the second region comprises a secondportion, whereby, at least about 50%, and preferably at least about 75%,at least about 90%, or at least about 95% of the nucleotide residuepositions of each of the portions are occupied by the same nucleotideresidue. More preferably, all nucleotide residue positions of each ofthe portions are occupied by the same nucleotide residue.

The term “immune cell” refers to cells that play a role in the immuneresponse. Immune cells are of hematopoietic origin, and includelymphocytes, such as B cells and T cells; natural killer cells; myeloidcells, such as monocytes, macrophages, eosinophils, mast cells,basophils, and granulocytes.

The term “immunotherapy” or “immunotherapies” refer to any treatmentthat uses certain parts of a subject's immune system to fight diseasessuch as cancer. The subject's own immune system is stimulated (orsuppressed), with or without administration of one or more agent forthat purpose. Immunotherapies that are designed to elicit or amplify animmune response are referred to as “activation immunotherapies.”Immunotherapies that are designed to reduce or suppress an immuneresponse are referred to as “suppression immunotherapies.” Any agentbelieved to have an immune system effect on the genetically modifiedtransplanted cancer cells can be assayed to determine whether the agentis an immunotherapy and the effect that a given genetic modification hason the modulation of immune response. In some embodiments, theimmunotherapy is cancer cell-specific. In some embodiments,immunotherapy can be “untargeted,” which refers to administration ofagents that do not selectively interact with immune system cells, yetmodulates immune system function. Representative examples of untargetedtherapies include, without limitation, chemotherapy, gene therapy, andradiation therapy.

Immunotherapy is one form of targeted therapy that may comprise, forexample, the use of cancer vaccines and/or sensitized antigen presentingcells. For example, an oncolytic virus is a virus that is able to infectand lyse cancer cells, while leaving normal cells unharmed, making thempotentially useful in cancer therapy. Replication of oncolytic virusesboth facilitates tumor cell destruction and also produces doseamplification at the tumor site. They may also act as vectors foranticancer genes, allowing them to be specifically delivered to thetumor site. The immunotherapy can involve passive immunity forshort-term protection of a host, achieved by the administration ofpre-formed antibody directed against a cancer antigen or disease antigen(e.g., administration of a monoclonal antibody, optionally linked to achemotherapeutic agent or toxin, to a tumor antigen). For example,anti-VEGF and mTOR inhibitors are known to be effective in treatingrenal cell carcinoma. Immunotherapy can also focus on using thecytotoxic lymphocyte-recognized epitopes of cancer cell lines.Alternatively, antisense polynucleotides, ribozymes, RNA interferencemolecules, triple helix polynucleotides and the like, can be used toselectively modulate biomolecules that are linked to the initiation,progression, and/or pathology of a tumor or cancer.

Immunotherapy can involve passive immunity for short-term protection ofa host, achieved by the administration of pre-formed antibody directedagainst a cancer antigen or disease antigen (e.g., administration of amonoclonal antibody, optionally linked to a chemotherapeutic agent ortoxin, to a tumor antigen). Immunotherapy can also focus on using thecytotoxic lymphocyte-recognized epitopes of cancer cell lines.Alternatively, antisense polynucleotides, ribozymes, RNA interferencemolecules, triple helix polynucleotides and the like, can be used toselectively modulate biomolecules that are linked to the initiation,progression, and/or pathology of a tumor or cancer.

In some embodiments, the immunotherapy described herein comprises atleast one of immunogenic chemotherapies. The term “immunogenicchemotherapy” refers to any chemotherapy that has been demonstrated toinduce immunogenic cell death, a state that is detectable by the releaseof one or more damage-associated molecular pattern (DAMP) molecules,including, but not limited to, calreticulin, ATP and HMGB1 (Kroemer etal. (2013), Annu. Rev. Immunol., 31:51-72). Specific representativeexamples of consensus immunogenic chemotherapies include anthracyclines,such as doxorubicin and the platinum drug, oxaliplatin, 5′-fluorouracil,among others.

In some embodiments, immunotherapy comprises inhibitors of one or moreimmune checkpoints. The term “immune checkpoint” refers to a group ofmolecules on the cell surface of CD4+ and/or CD8+ T cells that fine-tuneimmune responses by down-modulating or inhibiting an anti-tumor immuneresponse. Immune checkpoint proteins are well-known in the art andinclude, without limitation, CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1,B7-H4, B7-H6, ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR familyreceptors, TIM-1, TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA, SIRP,CD47, CD48, 2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT, HHLA2,butyrophilins, IDO, CD39, CD73 and A2aR (see, for example, WO2012/177624). The term further encompasses biologically active proteinfragment, as well as nucleic acids encoding full-length immunecheckpoint proteins and biologically active protein fragments thereof.In some embodiment, the term further encompasses any fragment accordingto homology descriptions provided herein. In one embodiment, the immunecheckpoint is PD-1.

Immune checkpoints and their sequences are well-known in the art andrepresentative embodiments are described below. For example, the term“PD-1” refers to a member of the immunoglobulin gene superfamily thatfunctions as a coinhibitory receptor having PD-L1 and PD-L2 as knownligands. PD-1 was previously identified using a subtraction cloningbased approach to select for genes upregulated during TCR-inducedactivated T cell death. PD-1 is a member of the CD28/CTLA-4 family ofmolecules based on its ability to bind to PD-L1. Like CTLA-4, PD-1 israpidly induced on the surface of T-cells in response to anti-CD3 (Agataet al. 25 (1996) Int. Immunol. 8:765). In contrast to CTLA-4, however,PD-1 is also induced on the surface of B-cells (in response toanti-IgM). PD-1 is also expressed on a subset of thymocytes and myeloidcells (Agata et al. (1996) supra; Nishimura et al. (1996) Int. Immunol.8:773).

“Anti-immune checkpoint therapy” refers to the use of agents thatinhibit immune checkpoint nucleic acids and/or proteins. Inhibition ofone or more immune checkpoints can block or otherwise neutralizeinhibitory signaling to thereby upregulate an immune response in orderto more efficaciously treat cancer. Exemplary agents useful forinhibiting immune checkpoints include antibodies, small molecules,peptides, peptidomimetics, natural ligands, and derivatives of naturalligands, that can either bind and/or inactivate or inhibit immunecheckpoint proteins, or fragments thereof; as well as RNA interference,antisense, nucleic acid aptamers, etc. that can downregulate theexpression and/or activity of immune checkpoint nucleic acids, orfragments thereof. Exemplary agents for upregulating an immune responseinclude antibodies against one or more immune checkpoint proteins blockthe interaction between the proteins and its natural receptor(s); anon-activating form of one or more immune checkpoint proteins (e.g., adominant negative polypeptide); small molecules or peptides that blockthe interaction between one or more immune checkpoint proteins and itsnatural receptor(s); fusion proteins (e.g. the extracellular portion ofan immune checkpoint inhibition protein fused to the Fc portion of anantibody or immunoglobulin) that bind to its natural receptor(s);nucleic acid molecules that block immune checkpoint nucleic acidtranscription or translation; and the like. Such agents can directlyblock the interaction between the one or more immune checkpoints and itsnatural receptor(s) (e.g., antibodies) to prevent inhibitory signalingand upregulate an immune response. Alternatively, agents can indirectlyblock the interaction between one or more immune checkpoint proteins andits natural receptor(s) to prevent inhibitory signaling and upregulatean immune response. For example, a soluble version of an immunecheckpoint protein ligand such as a stabilized extracellular domain canbinding to its receptor to indirectly reduce the effective concentrationof the receptor to bind to an appropriate ligand. In one embodiment,anti-PD-1 antibodies, anti-PD-L1 antibodies, and/or anti-PD-L2antibodies, either alone or in combination, are used to inhibit immunecheckpoints. These embodiments are also applicable to specific therapyagainst particular immune checkpoints, such as the PD-1 pathway (e.g.,anti-PD-1 pathway therapy, otherwise known as PD-1 pathway inhibitortherapy).

The term “TP53” refers to Tumor Protein P53, a tumor suppressor proteincontaining transcriptional activation, DNA binding, and oligomerizationdomains. The encoded protein responds to diverse cellular stresses toregulate expression of target genes, thereby inducing cell cycle arrest,apoptosis, senescence, DNA repair, or changes in metabolism. Mutationsin this gene are associated with a variety of human cancers, includinghereditary cancers such as Li-Fraumeni syndrome. TP53 mutations areuniversal across cancer types. The loss of a tumor suppressor is mostoften through large deleterious events, such as frameshift mutations, orpremature stop codons. In TP53 however, many of the observed mutationsin cancer are found to be single nucleotide missense variants. Thesevariants are broadly distributed throughout the gene, but with themajority localizing in the DNA binding domain. There is no singlehotspot in the DNA binding domain, but a majority of mutations occur inamino acid positions 175, 245, 248, 273, and 282 (NM 000546). While alarge proportion of cancer genomics research is focused on somaticvariants, TP53 is also of note in the germline. Germline TP53 mutationsare the hallmark of Li-Fraumeni syndrome, and many (both germline andsomatic) variants have been found to have a prognostic impact on patientoutcomes. TP53 acts as a tumor suppressor in many tumor types byinducing growth arrest or apoptosis depending on the physiologicalcircumstances and cell type. TP53 is involved in cell cycle regulationas a trans-activator that acts to negatively regulate cell division bycontrolling a set of genes required for this process. One of theactivated genes is an inhibitor of cyclin-dependent kinases. Apoptosisinduction seems to be mediated either by stimulation of BAX and FASantigen expression, or by repression of Bcl-2 expression. In cooperationwith mitochondrial PPIF, TP53 is involved in activating oxidativestress-induced necrosis, and the function is largely independent oftranscription. TP53 induces the transcription of long intergenicnon-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21participates in TP53-dependent transcriptional repression leading toapoptosis and seem to have to effect on cell-cycle regulation. TP53 isimplicated in Notch signaling cross-over. TP53 prevents CDK7 kinaseactivity when associated to CAK complex in response to DNA damage, thusstopping cell cycle progression. Isoform 2 of TP53 enhances thetransactivation activity of isoform 1 from some but not allTP53-inducible promoters. Isoform 4 of TP53 suppresses transactivationactivity and impairs growth suppression mediated by isoform 1. Isoform 7of TP53 inhibits isoform 1-mediated apoptosis. TP53 regulates thecircadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptionalactivation of PER2 (Miki et al., (2013) Nat Commun 4:2444). In someembodiments, human TP53 protein has 393 amino acids and a molecular massof 43653 Da. The known binding partners of TP53 include, e.g., AXIN1,ING4, YWHAZ, HIPK1, HIPK2, WWOX, GRKS, ANKRD2, RFFL, RNF 34, andTP53INP1.

The term “TP53” is intended to include fragments, variants (e.g.,allelic variants), and derivatives thereof. Representative human TP53cDNA and human TP53 protein sequences are well-known in the art and arepublicly available from the National Center for BiotechnologyInformation (NCBI). For example, at least 12 different human TP53isoforms are known. Human TP53 isoform a (NP_000537.3, NP_001119584.1)is encodable by the transcript variant 1 (NM_000546.5) and thetranscript variant 2 (NM_001126112.2). Human TP53 isoform b(NP_001119586.1) is encodable by the transcript variant 3(NM_001126114.2). Human TP53 isoform c (NP_001119585.1) is encodable bythe transcript variant 4 (NM_001126113.2). Human TP53 isoform d(NP_001119587.1) is encodable by the transcript variant 5(NM_001126115.1). Human TP53 isoform e (NP_001119588.1) is encodable bythe transcript variant 6 (NM_001126116.1). Human TP53 isoform f(NP_001119589.1) is encodable by the transcript variant 7(NM_001126117.1). Human TP53 isoform g (NP_001119590.1, NP_001263689.1,and NP_001263690.1) is encodable by the transcript variant 8(NM_001126118.1), the transcript variant 1 (NM_001276760.1), and thetranscript variant 2 (NM_001276761.1). Human TP53 isoform h(NP_001263624.1) is encodable by the transcript variant 4(NM_001276695.1). Human TP53 isoform i (NP_001263625.1) is encodable bythe transcript variant 3 (NM_001276696.1). Human TP53 isoform j(NP_001263626.1) is encodable by the transcript variant 5(NM_001276697.1). Human TP53 isoform k (NP_001263627.1) is encodable bythe transcript variant 6 (NM_001276698.1). Human TP53 isoform 1(NP_001263628.1) is encodable by the transcript variant 7(NM_001276699.1). Nucleic acid and polypeptide sequences of TP53orthologs in organisms other than humans are well known and include, forexample, chimpanzee TP53 (XM 001172077.5 and XP 001172077.2, and XM016931470.2 and) CP 016786959.2), monkey TP53 (NM_001047151.2 andNP_001040616.1), dog TP53 (NM_001003210.1 and NP_001003210.1), cattleTP53 (NM_174201.2 and NP_776626.1), mouse TP53 (NM_001127233.1 andNP_001120705.1, and NM_011640.3 and NP_035770.2), rat TP53 (NM_030989.3and NP_112251.2), tropical clawed frog TP53 (NM_001001903.1 andNP_001001903.1), and zebrafish TP53 (NM_001271820.1 and NP_001258749.1,NM_001328587.1 and NP_001315516.1, NM_001328588.1 and NP_001315517.1,and NM_131327.2 and NP_571402.1). Representative sequences of TP53orthologs are presented below in Table 1A.

Anti-TP53 antibodies suitable for detecting TP53 protein are well-knownin the art and include, for example, antibodies TA502925 and CF502924(Origene), antibodies NB200-103 and NB200-171 (Novus Biologicals,Littleton, Colo.), antibodies ab26 and ab1101 (AbCam, Cambridge, Mass.),antibody 700439 (ThermoFisher Scientific), antibody 33-856 (ProSci),etc. In addition, reagents are well-known for detecting TP53. Multipleclinical tests of TP53 are available in NIH Genetic Testing Registry(GTR®) (e.g., GTR Test ID: GTR000517320.2, offered by Fulgent ClinicalDiagnostics Lab (Temple City, Calif.)). Moreover, multiple siRNA, shRNA,CRISPR constructs for reducing TP53 expression can be found in thecommercial product lists of the above-referenced companies, such assiRNA products #sc-29435 and sc-44218, and CRISPR product # sc-416469from Santa Cruz Biotechnology, RNAi products SR322075 and TL320558V, andCRISPR product KN200003 (Origene), and multiple CRISPR products fromGenScript (Piscataway, N.J.). Chemical inhibitors of TP53 are alsoavailable, including, e.g., Cyclic Pifithrin-a hydrobromide, RITA(TOCRIS, Minn.). It is to be noted that the term can further be used torefer to any combination of features described herein regarding TP53molecules. For example, any combination of sequence composition,percentage identify, sequence length, domain structure, functionalactivity, etc. can be used to describe a TP53 molecule encompassed bythe present invention.

The term “RB1”, also known as RB transcriptional corepressor 1, is anegative regulator of the cell cycle and was the first tumor suppressorgene found. The encoded protein also stabilizes constitutiveheterochromatin to maintain the overall chromatin structure. The active,hypophosphorylated form of the protein binds transcription factor E2F1.Defects in this gene are a cause of childhood cancer retinoblastoma(RB), bladder cancer, and osteogenic sarcoma. RB1 is a key regulator ofentry into cell division that acts as a tumor suppressor. It promotesG0-G1 transition when phosphorylated by CDK3/cyclin-C. RB1 acts as atranscription repressor of E2F1 target genes. The underphosphorylated,active form of RB1 interacts with E2F1 and represses its transcriptionactivity, leading to cell cycle arrest. RB1 is also directly involved inheterochromatin formation by maintaining overall chromatin structureand, in particular, that of constitutive heterochromatin by stabilizinghistone methylation. RB1 recruits and targets histone methyltransferasesSUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptionalrepression. It controls histone H4 ‘Lys-20’ trimethylation. RB1 inhibitsthe intrinsic kinase activity of TAF1. It mediates transcriptionalrepression by SMARCA4/BRG1 by recruiting a histone deacetylase (HDAC)complex to the c-FOS promoter. In resting neurons, transcription of thec-FOS promoter is inhibited by BRG1-dependent recruitment of aphospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 isdephosphorylated by calcineurin, which leads to release of the repressorcomplex. In case of viral infections, RB1 interactions with SV40 large Tantigen, HPV E7 protein or adenovirus E1A protein and induces thedisassembly of RB1-E2F1 complex thereby disrupting RB1's activity.

The term “RB1” is intended to include fragments, variants (e.g., allelicvariants), and derivatives thereof. Representative human RB1 cDNA andhuman RB1 protein sequences are well-known in the art and are publiclyavailable from the National Center for Biotechnology Information (NCBI).For example, at least one different human RB1 isoforms are known. HumanRB1 protein (NP_000312.2) is encodable by the transcript (NM_000321.2).Nucleic acid and polypeptide sequences of RB1 orthologs in organismsother than humans are well known and include, for example, chimpanzeeRB1 (XM_509777.4 and XP 509777.3, and XM_016925689.1 and XP016781178.1), dog RB1 (XM_022408288.1 and XP 022263996.1), cattle RB1(NM_001076907.1 and NP_001070375.1), mouse RB1 (NM_009029.3 andNP_033055.2), rat RB1 (NM_017045.1 and NP_058741.1), chicken RB1(NM_204419.1 and NP_989750.1), tropical clawed frog RB1 (NM_001282525.1and NP_001269454.1), and zebrafish RB1 (NM_001077780.1 andNP_001071248.1). Representative sequences of RB1 orthologs are presentedbelow in Table 1A.

The term “CYLD,” also known as “CYLD lysine 63 deubiquitinase,” refersto a cytoplasmic protein with three cytoskeletal-associatedprotein-glycine-conserved (CAP-GLY) domains that functions as adeubiquitinating enzyme. Mutations in this gene have been associatedwith cylindromatosis, multiple familial trichoepithelioma, andBrooke-Spiegler syndrome. CYLD is a deubiquitinase that specificallycleaves Lys-63- and linear Met-1-linked polyubiquitin chains and isinvolved in NF-kappa-B activation and TNF-alpha-induced necroptosis. Itplays an important role in the regulation of pathways leading toNF-kappa-B activation. CYLD contributes to the regulation of cellsurvival, proliferation and differentiation via its effects onNF-kappa-B activation. It is also a negative regulator of Wnt signaling.CYLD inhibits HDAC6 and thereby promotes acetylation of alpha-tubulinand stabilization of microtubules. It plays a role in the regulation ofmicrotubule dynamics, and thereby contributes to the regulation of cellproliferation, cell polarization, cell migration, and angiogenesis. CYLDis required for normal cell cycle progress and normal cytokinesis. Itinhibits nuclear translocation of NF-kappa-B. CYLD plays a role in theregulation of inflammation and the innate immune response, via itseffects on NF-kappa-B activation. It is dispensable for the maturationof intrathymic natural killer cells, but required for the continuedsurvival of immature natural killer cells. In addition, CYLD negativelyregulates TNFRSF11A signaling and osteoclastogenesis, and is involved inthe regulation of ciliogenesis, allowing ciliary basal bodies to migrateand dock to the plasma membrane; this process does not depend onNF-kappa-B activation. CYLD is able to remove linear (Met-1-linked)polyubiquitin chains and regulates innate immunity and TNF-alpha-inducednecroptosis. It is recruited to the LUBAC complex via interaction withSPATA2 and restricts linear polyubiquitin formation on target proteins.Furthermore, CYLD regulates innate immunity by restricting linearpolyubiquitin formation on RIPK2 in response to NOD2 stimulation. CYLDis involved in TNF-alpha-induced necroptosis by removing linear(Met-1-linked) polyubiquitin chains from RIPK1, thereby regulating thekinase activity of RIPK1. CYLD removes Lys linked polyubiquitin chain ofMAP3K7, which inhibits phosphorylation and blocks downstream activationof the JNK-p38 kinase cascades.

The term “CYLD” is intended to include fragments, variants (e.g.,allelic variants), and derivatives thereof. Representative human CYLDcDNA and human CYLD protein sequences are well-known in the art and arepublicly available from the National Center for BiotechnologyInformation (NCBI). For example, at least 3 different human CYLDisoforms are known. Human CYLD isoform 1 (NP_056062.1) is encodable bythe transcript variant 1 (NM_015247.2). Human CYLD isoform 2(NP_001035814.1 and NP_001035877.1) is encodable by the transcriptvariant 2 (NM_001042355.2) and the transcript variant 3(NM_001042412.2). Nucleic acid and polypeptide sequences of CYLDorthologs in organisms other than humans are well known and include, forexample, chimpanzee CYLD (XM_016929820.2 and XP 016785309.1,XM_016929821.2 and) CP_016785310.1, XM_016929822.2 and XP 016785311.1,XM_016929818.2 and XP_016785307.1, XM_009430770.3 and XP_009429045.1,and XM_016929819.2 and XP_016785308.1), monkey CYLD (XM_015126108.2 and(CP_014981594.1, XM_015126112.2 and XP_014981598.1, XM_015126111.2 andXP_014981597.1, XM_015126109.2 and XP_014981595.1, and XM_015126113.2and XP_014981599.1), dog CYLD (XM_005617567.3 and XP_005617624.1,XM_005617569.3 and XP_005617626.1, XM_005617568.3 and XP_005617625.1,and XM_849343.5 and XP_854436.1), cattle CYLD (NM_001046417.1 andNP_001039882.1), mouse CYLD (NM_001128170.2 and NP_001121642.1,NM_001128171.2 and NP_001121643.1, NM_001276279.1 and NP_001263208.1,and NM_173369.3 and NP_775545.1), rat CYLD (NM_001017380.1 andNP_001017380.1), and chicken CYLD (XM_015292398.2 and XP_015147884.2).Representative sequences of CYLD orthologs are presented below in Table1A.

“Androgen receptor” (“AR”) refers to the steroid receptor that islocated in the cytoplasm and translocated to the nucleus uponstimulation with androgen or an androgen analogue. AR is a solubleprotein that functions as an intracellular transcription factor. Thefunction of AR is regulated by the binding of androgen, which initiatessuccessive conformational changes in the receptor and thus affects theinteraction between the receptor and the protein and the interactionbetween the receptor and DNA. AR mediates the induction of variousbiological effects through interaction with endogenous androgens.Endogenous androgens include steroids such as testosterone anddihydrotinone. In many tissues, testosterone is converted todihydrocinone by enzyme 5α-reductase.

AR is mainly expressed in androgen target tissues such as prostate,skeletal muscle, liver and central nervous system (CNS), while thehighest observed in the prostate, adrenal gland and parasitoid. AR canbe activated by binding to endogenous androgens, including testosteroneand 5α-dihydrosterolone (5α-DHT).

The Xq11-12 androgen receptor (AR) is a 110 kD nuclear receptor thatmediates transcription of a target gene that regulates differentiationand growth of prostate epithelial cells upon activation by androgen.Similar to other steroid receptors, unbound AR is primarily located inthe cytoplasm and is associated with complexes of heat shock proteins(HSPs) by interacting with ligand binding domains. After binding to theagonist, the AR undergoes a series of conformational changes: the heatshock protein is isolated from the AR, and the transformed AR isdimerized, phosphorylated, and mediated by the nuclear localizationsignal to the nucleus. The transfer site receptor then binds to theandrogen response unit (ARE), which is characterized by a hexanucleotidehalf-site consensus sequence 5′-TGTTCT-3′ (by three random nucleotides)Interval) and located in the promoter or enhancer region of the ARtarget gene. The convening of other transcriptional co-regulators(including co-activators and co-repressors) and transcriptionalmachinery further ensures transcriptional activation of AR-regulatedgene expression. All of these processes are initiated by ligand-inducedconformational changes in the ligand binding domain.

The effects of androgen and androgen receptors are known to beassociated with diseases or conditions such as prostate cancer, breastcancer, androgen-dependent hirsutism, male alopecia, uterine fibroids,leiomyoma, endometrial cancer or endometrium. The signaling of AR iscritical for the development and maintenance of the male reproductiveorgans, including the prostate, because male genetically inactive ARmutants and genetically engineered AR-deficient mice do not developprostate or prostate cancer. The dependence of prostate cells on ARsignal transmission persists even after malignant tumor formation.Androgen depletion (such as the use of GnRH agonists) remains theprimary method of treating prostate cancer. However, androgen removaloften only effective for a limited period of time, although the amountof circulating androgen is very low, prostate cancer will graduallyresume growth. Castration-resistant prostate cancer (CRPC) is a fatalphenotype and almost all patients die of prostate cancer.

The term “AR” is intended to include fragments, variants (e.g., allelicvariants), and derivatives thereof. Representative human AR cDNA andhuman AR protein sequences are well-known in the art and are publiclyavailable from the National Center for Biotechnology Information (NCBI).For example, at least 5 different human AR isoforms are known. Human ARisoform 1 (NP_000035.2) is encodable by the transcript variant 1(NM_000044.6). Human AR isoform 2 (NP_001011645.1) is encodable by thetranscript variant 2 (NM_001011645.3). Human AR isoform 3(NP_001334990.1) is encodable by the transcript variant 3(NM_001348061.1). Human AR isoform 4 (NP_001334992.1) is encodable bythe transcript variant 4 (NM_001348063.1). Human AR isoform 5(NP_001334993.1) is encodable by the transcript variant 5(NM_001348064.1). Nucleic acid and polypeptide sequences of AR orthologsin organisms other than humans are well known and include, for example,monkey AR (NM_001032911.1 and NP_001028083.1), dog AR (NM_001003053.1and NP_001003053.1), cattle AR (NM_001244127.1 and NP_001231056.1),mouse AR (NM_013476.4 and NP_038504.1), rat AR (NM_012502.1 andNP_036634.1), and chicken AR (NM_001040090.1 and NP_001035179.1).Representative sequences of AR orthologs are presented below in Table1B.

The term “androgen receptor-directed therapy” to any therapy used forthe treatment of prostate cancer by targeting androgen receptor(AR)-signaling in the subject. The therapy may act through inhibition ofandrogen synthesis or through AR targeting directly. Exemplary androgenreceptor (AR)-directed therapies include, but are not limited toabiraterone or enzalutamide.

The term “NEPC score” refers to a score that is calculated based on thecombination of specific genomic and/or epigenomic alterations ofbiomarkers described herein. In one embodiment, this score may be usedto diagnose whether a subject is afflicted with castration-resistantneuroendocrine prosate cancer (CRPC-NE) or at risk for developingCRPC-NE. In another embodiment, it may be used to monitor theprogression of CRPC or predict the efficacy of an agent for treatingCRPC-NE in a subject. In still another embodiment, it may be used topredict the likelihood of response to an AR-targeted therapy in asubject afflicted with CRPC. The NEPC score may be calculated accordingto the methods described in example 1 of the present disclosure.

The term “epigenomic alteration” refers to any epigenetic modificationon the genetic material (e.g., genomic DNA) of a cell or a subject. Incertain embodiment, the epigenomic alteration is DNA methylation. DNAmethylation is a chemical modification of DNA performed by enzymescalled methyltransferases, in which a methyl group (m) is added tocertain cytosines (C) of DNA. This non-mutational (epigenetic) process(mC) is a critical factor in gene expression regulation. DNA methylationplays an important role in determining gene expression. By turning genesoff that are not needed, DNA methylation is an essential controlmechanism for the normal development and functioning of organisms.Alternatively, abnormal DNA methylation is one of the mechanismsunderlying the changes observed with the development of many cancers.

The best-defined epigenetic alteration of cancer genes involves DNAmethylation of clustered CpG dinucleotides, or CpG islands, in promoterregions associated with the transcriptional inactivation of the affectedgenes. CpG islands are short sequences rich in the CpG dinucleotide, andcan be found in the 5′ region of about half of all human genes.Methylation of cytosine within 5′ CGIs is associated with loss of geneexpression and has been seen in a number of physiological conditions,including X chromosome inactivation and genomic imprinting. Aberrantmethylation of CpG islands has been detected in genetic diseases such asthe fragile-X syndrome, in aging cells and in neoplasia. About half ofthe tumor suppressor genes which have been shown to be mutated in thegermline of patients with familial cancer syndromes have also been shownto be aberrantly methylated in some proportion of sporadic cancers,including Rb, VHL, p16, hMLH1, and BRCA1. Methylation of tumorsuppressor genes in cancer is usually associated with (1) lack of genetranscription and (2) absence of coding region mutation. Thus CpG islandmethylation can serve as an alternative mechanism of gene inactivationin cancer.

The term “hypermethylation” refers to an increase in the epigeneticmethylation of cytosine and adenosine residues in DNA from a samplecompared to a control. The term “hypomethylation” refers to a decreasein the epigenetic methylation of cytosine and adenosine residues in DNAfrom a sample compared to a control. In certain embodiments, the controlis a site specific tissue-based threshold that discriminates betweencastration resistant prostate adenocarcinoma (CRPC-Adeno) and CRPC-NEtissue samples. Such thresholds can be determined using methodsdescribed in example 1. In some embodiment, the control is the sitespecific tissue-based methylation level determined in CRPC-Adenosamples.

The term “immune response” includes T cell mediated and/or B cellmediated immune responses. Exemplary immune responses include T cellresponses, e.g., cytokine production and cellular cytotoxicity. Inaddition, the term immune response includes immune responses that areindirectly effected by T cell activation, e.g., antibody production(humoral responses) and activation of cytokine responsive cells, e.g.,macrophages.

The term “immunotherapeutic agent” can include any molecule, peptide,antibody or other agent which can stimulate a host immune system togenerate an immune response to a tumor or cancer in the subject. Variousimmunotherapeutic agents are useful in the compositions and methodsdescribed herein.

The term “inhibit” includes the decrease, limitation, or blockage, of,for example a particular action, function, or interaction. In someembodiments, cancer is “inhibited” if at least one symptom of the canceris alleviated, terminated, slowed, or prevented. As used herein, canceris also “inhibited” if recurrence or metastasis of the cancer isreduced, slowed, delayed, or prevented.

The term “interaction”, when referring to an interaction between twomolecules, refers to the physical contact (e.g., binding) of themolecules with one another. Generally, such an interaction results in anactivity (which produces a biological effect) of one or both of saidmolecules.

An “isolated protein” refers to a protein that is substantially free ofother proteins, cellular material, separation medium, and culture mediumwhen isolated from cells or produced by recombinant DNA techniques, orchemical precursors or other chemicals when chemically synthesized. An“isolated” or “purified” protein or biologically active portion thereofis substantially free of cellular material or other contaminatingproteins from the cell or tissue source from which the antibody,polypeptide, peptide or fusion protein is derived, or substantially freefrom chemical precursors or other chemicals when chemically synthesized.The language “substantially free of cellular material” includespreparations of a biomarker polypeptide or fragment thereof, in whichthe protein is separated from cellular components of the cells fromwhich it is isolated or recombinantly produced. In one embodiment, thelanguage “substantially free of cellular material” includes preparationsof a biomarker protein or fragment thereof, having less than about 30%(by dry weight) of non-biomarker protein (also referred to herein as a“contaminating protein”), more preferably less than about 20% ofnon-biomarker protein, still more preferably less than about 10% ofnon-biomarker protein, and most preferably less than about 5%non-biomarker protein. When antibody, polypeptide, peptide or fusionprotein or fragment thereof, e.g., a biologically active fragmentthereof, is recombinantly produced, it is also preferably substantiallyfree of culture medium, i.e., culture medium represents less than about20%, more preferably less than about 10%, and most preferably less thanabout 5% of the volume of the protein preparation.

As used herein, the term “isotype” refers to the antibody class (e.g.,IgM, IgG1, IgG2C, and the like) that is encoded by heavy chain constantregion genes.

As used herein, the term “K_(D)” is intended to refer to thedissociation equilibrium constant of a particular antibody-antigeninteraction. The binding affinity of antibodies of the disclosedinvention may be measured or determined by standard antibody-antigenassays, for example, competitive assays, saturation assays, or standardimmunoassays such as ELISA or RIA.

A “kit” is any manufacture (e.g. a package or container) comprising atleast one reagent, e.g. a probe or small molecule, for specificallydetecting and/or affecting the expression of a marker of the presentinvention. The kit may be promoted, distributed, or sold as a unit forperforming the methods of the present invention. The kit may compriseone or more reagents necessary to express a composition useful in themethods of the present invention. In certain embodiments, the kit mayfurther comprise a reference standard, e.g., a nucleic acid encoding aprotein that does not affect or regulate signaling pathways controllingcell growth, division, migration, survival or apoptosis. One skilled inthe art can envision many such control proteins, including, but notlimited to, common molecular tags (e.g., green fluorescent protein andbeta-galactosidase), proteins not classified in any of pathwayencompassing cell growth, division, migration, survival or apoptosis byGeneOntology reference, or ubiquitous housekeeping proteins. Reagents inthe kit may be provided in individual containers or as mixtures of twoor more reagents in a single container. In addition, instructionalmaterials which describe the use of the compositions within the kit canbe included.

The term “neoadjuvant therapy” refers to a treatment given before theprimary treatment. Examples of neoadjuvant therapy can includechemotherapy, radiation therapy, and hormone therapy. For example, intreating breast cancer, neoadjuvant therapy can allows patients withlarge breast cancer to undergo breast-conserving surgery.

The “normal” level of expression of a biomarker is the level ofexpression of the biomarker in cells of a subject, e.g., a humanpatient, not afflicted with a cancer. An “over-expression” or“significantly higher level of expression” of a biomarker refers to anexpression level in a test sample that is greater than the standarderror of the assay employed to assess expression, and is preferably atleast 10%, and more preferably 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9,2.0, 2.1, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3, 3.5, 4, 4.5,5, 5.5, 6, 6.5, 7, 7.5, 8, 8.5, 9, 9.5, 10, 10.5, 11, 12, 13, 14, 15,16, 17, 18, 19, 20 times or more higher than the expression activity orlevel of the biomarker in a control sample (e.g., sample from a healthysubject not having the biomarker associated disease) and preferably, theaverage expression level of the biomarker in several control samples. A“significantly lower level of expression” of a biomarker refers to anexpression level in a test sample that is at least 10%, and morepreferably 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 2.0, 2.1, 2.1, 2.2,2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7,7.5, 8, 8.5, 9, 9.5, 10, 10.5, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20times or more lower than the expression level of the biomarker in acontrol sample (e.g., sample from a healthy subject not having thebiomarker associated disease) and preferably, the average expressionlevel of the biomarker in several control samples.

An “over-expression” or “significantly higher level of expression” of abiomarker refers to an expression level in a test sample that is greaterthan the standard error of the assay employed to assess expression, andis preferably at least 10%, and more preferably 1.2, 1.3, 1.4, 1.5, 1.6,1.7, 1.8, 1.9, 2.0, 2.1, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3,3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, 7.5, 8, 8.5, 9, 9.5, 10, 10.5, 11, 12,13, 14, 15, 16, 17, 18, 19, 20 times or more higher than the expressionactivity or level of the biomarker in a control sample (e.g., samplefrom a healthy subject not having the biomarker associated disease) andpreferably, the average expression level of the biomarker in severalcontrol samples. A “significantly lower level of expression” of abiomarker refers to an expression level in a test sample that is atleast 10%, and more preferably 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9,2.0, 2.1, 2.1, 2.2, 2.3, 2.4, 2.5, 2.6, 2.7, 2.8, 2.9, 3, 3.5, 4, 4.5,5, 5.5, 6, 6.5, 7, 7.5, 8, 8.5, 9, 9.5, 10, 10.5, 11, 12, 13, 14, 15,16, 17, 18, 19, 20 times or more lower than the expression level of thebiomarker in a control sample (e.g., sample from a healthy subject nothaving the biomarker associated disease) and preferably, the averageexpression level of the biomarker in several control samples.

The term “pre-determined” biomarker genomic and/or epigenomicalteration(s) may be a biomarker genomic and/or epigenomic alteration(s)used to, by way of example only, evaluate a subject that may be selectedfor a particular treatment, evaluate a response to a treatment, and/orevaluate the disease state. A pre-determined biomarker genomic and/orepigenomic alteration(s) may be determined in populations of patientswith or without cancer. The pre-determined biomarker genomic and/orepigenomic alteration(s) can be a single number, equally applicable toevery patient, or the pre-determined biomarker genomic and/or epigenomicalteration(s) can vary according to specific subpopulations of patients.Age, weight, height, and other factors of a subject may affect thepre-determined biomarker genomic and/or epigenomic alteration(s) of theindividual. Furthermore, the pre-determined biomarker amount and/oractivity can be determined for each subject individually. In oneembodiment, the amounts determined and/or compared in a method describedherein are based on absolute measurements. In another embodiment, theamounts determined and/or compared in a method described herein arebased on relative measurements, such as ratios (e.g., serum biomarkernormalized to the expression of housekeeping or otherwise generallyconstant biomarker). The pre-determined biomarker genomic and/orepigenomic alteration(s) can be any suitable standard. For example, thepre-determined biomarker genomic and/or epigenomic alteration(s) can beobtained from the same or a different human for whom a patient selectionis being assessed. In one embodiment, the pre-determined biomarkergenomic and/or epigenomic alteration(s) can be obtained from a previousassessment of the same patient. In such a manner, the progress of theselection of the patient can be monitored over time. In addition, thecontrol can be obtained from an assessment of another human or multiplehumans, e.g., selected groups of humans, if the subject is a human. Insuch a manner, the extent of the selection of the human for whomselection is being assessed can be compared to suitable other humans,e.g., other humans who are in a similar situation to the human ofinterest, such as those suffering from similar or the same condition(s)and/or of the same ethnic group.

The term “predictive” includes the use of a biomarker nucleic acidand/or protein status, e.g., over- or under-activity, emergence,expression, growth, remission, recurrence or resistance of tumorsbefore, during or after therapy, for determining the likelihood ofresponse of a cancer to an anti-cancer therapy. Such predictive use ofthe biomarker may be confirmed by, e.g., (1) increased or decreased copynumber (e.g., by FISH, FISH plus SKY, single-molecule sequencing, e.g.,as described in the art at least at J. Biotechnol., 86:289-301, orqPCR), overexpression or underexpression of a biomarker nucleic acid(e.g., by ISH, Northern Blot, or qPCR), increased or decreased biomarkerprotein (e.g., by IHC), or increased or decreased activity, e.g., inmore than about 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 20%,25%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95%, 100%, or more of assayedhuman cancers types or cancer samples; (2) its absolute or relativelymodulated presence or absence in a biological sample, e.g., a samplecontaining tissue, whole blood, serum, plasma, buccal scrape, saliva,cerebrospinal fluid, urine, stool, or bone marrow, from a subject, e.g.a human, afflicted with cancer; (3) its absolute or relatively modulatedpresence or absence in clinical subset of patients with cancer.

The term “pre-malignant lesions” as described herein refers to a lesionthat, while not cancerous, has potential for becoming cancerous. It alsoincludes the term “pre-malignant disorders” or “potentially malignantdisorders.” In particular this refers to a benign, morphologicallyand/or histologically altered tissue that has a greater than normal riskof malignant transformation, and a disease or a patient's habit thatdoes not necessarily alter the clinical appearance of local tissue butis associated with a greater than normal risk of precancerous lesion orcancer development in that tissue (leukoplakia, erythroplakia,erytroleukoplakia lichen planus (lichenoid reaction) and any lesion oran area which histological examination showed atypia of cells ordysplasia. In one embodiment, a metaplasia is a pre-malignant lesion.

The terms “prevent,” “preventing,” “prevention,” “prophylactictreatment,” and the like refer to reducing the probability of developinga disease, disorder, or condition in a subject, who does not have, butis at risk of or susceptible to developing a disease, disorder, orcondition.

The term “probe” refers to any molecule which is capable of selectivelybinding to a specifically intended target molecule, for example, anucleotide transcript or protein encoded by or corresponding to abiomarker nucleic acid. Probes can be either synthesized by one skilledin the art, or derived from appropriate biological preparations. Forpurposes of detection of the target molecule, probes may be specificallydesigned to be labeled, as described herein. Examples of molecules thatcan be utilized as probes include, but are not limited to, RNA, DNA,proteins, antibodies, and organic molecules.

The term “prognosis” includes a prediction of the probable course andoutcome of cancer or the likelihood of recovery from the disease. Insome embodiments, the use of statistical algorithms provides a prognosisof cancer in an individual. For example, the prognosis can be surgery,development of a clinical subtype of cancer (e.g., solid tumors, such asesophageal cancer and gastric cancer), development of one or moreclinical factors, or recovery from the disease.

The term “response to an anti-cancer therapy” relates to any response ofthe hyperproliferative disorder (e.g., cancer) to an anti-cancer agent,preferably to a change in tumor mass and/or volume after initiation ofneoadjuvant or adjuvant therapy. Hyperproliferative disorder responsemay be assessed, for example for efficacy or in a neoadjuvant oradjuvant situation, where the size of a tumor after systemicintervention can be compared to the initial size and dimensions asmeasured by CT, PET, mammogram, ultrasound or palpation. Responses mayalso be assessed by caliper measurement or pathological examination ofthe tumor after biopsy or surgical resection. Response may be recordedin a quantitative fashion like percentage change in tumor volume or in aqualitative fashion like “pathological complete response” (pCR),“clinical complete remission” (cCR), “clinical partial remission” (cPR),“clinical stable disease” (cSD), “clinical progressive disease” (cPD) orother qualitative criteria. Assessment of hyperproliferative disorderresponse may be done early after the onset of neoadjuvant or adjuvanttherapy, e.g., after a few hours, days, weeks or preferably after a fewmonths. A typical endpoint for response assessment is upon terminationof neoadjuvant chemotherapy or upon surgical removal of residual tumorcells and/or the tumor bed. This is typically three months afterinitiation of neoadjuvant therapy. In some embodiments, clinicalefficacy of the therapeutic treatments described herein may bedetermined by measuring the clinical benefit rate (CBR). The clinicalbenefit rate is measured by determining the sum of the percentage ofpatients who are in complete remission (CR), the number of patients whoare in partial remission (PR) and the number of patients having stabledisease (SD) at a time point at least 6 months out from the end oftherapy. The shorthand for this formula is CBR=CR+PR+SD over 6 months.In some embodiments, the CBR for a particular cancer therapeutic regimenis at least 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%,85%, or more. Additional criteria for evaluating the response to cancertherapies are related to “survival,” which includes all of thefollowing: survival until mortality, also known as overall survival(wherein said mortality may be either irrespective of cause or tumorrelated); “recurrence-free survival” (wherein the term recurrence shallinclude both localized and distant recurrence); metastasis freesurvival; disease free survival (wherein the term disease shall includecancer and diseases associated therewith). The length of said survivalmay be calculated by reference to a defined start point (e.g., time ofdiagnosis or start of treatment) and end point (e.g., death, recurrenceor metastasis). In addition, criteria for efficacy of treatment can beexpanded to include response to chemotherapy, probability of survival,probability of metastasis within a given time period, and probability oftumor recurrence. For example, in order to determine appropriatethreshold values, a particular cancer therapeutic regimen can beadministered to a population of subjects and the outcome can becorrelated to biomarker measurements that were determined prior toadministration of any cancer therapy. The outcome measurement may bepathologic response to therapy given in the neoadjuvant setting.Alternatively, outcome measures, such as overall survival anddisease-free survival can be monitored over a period of time forsubjects following cancer therapy for which biomarker measurement valuesare known. In certain embodiments, the doses administered are standarddoses known in the art for cancer therapeutic agents. The period of timefor which subjects are monitored can vary. For example, subjects may bemonitored for at least 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 25, 30, 35,40, 45, 50, 55, or 60 months. Biomarker measurement threshold valuesthat correlate to outcome of a cancer therapy can be determined usingwell-known methods in the art, such as those described in the Examplessection.

The term “resistance” refers to an acquired or natural resistance of acancer sample or a mammal to a cancer therapy (i.e., being nonresponsiveto or having reduced or limited response to the therapeutic treatment),such as having a reduced response to a therapeutic treatment by 25% ormore, for example, 30%, 40%, 50%, 60%, 70%, 80%, or more, to 2-fold,3-fold, 4-fold, 5-fold, 10-fold, 15-fold, 20-fold or more. The reductionin response can be measured by comparing with the same cancer sample ormammal before the resistance is acquired, or by comparing with adifferent cancer sample or a mammal that is known to have no resistanceto the therapeutic treatment. A typical acquired resistance tochemotherapy is called “multidrug resistance.” The multidrug resistancecan be mediated by P-glycoprotein or can be mediated by othermechanisms, or it can occur when a mammal is infected with amulti-drug-resistant microorganism or a combination of microorganisms.The determination of resistance to a therapeutic treatment is routine inthe art and within the skill of an ordinarily skilled clinician, forexample, can be measured by cell proliferative assays and cell deathassays as described herein as “sensitizing.” In some embodiments, theterm “reverses resistance” means that the use of a second agent incombination with a primary cancer therapy (e.g., chemotherapeutic orradiation therapy) is able to produce a significant decrease in tumorvolume at a level of statistical significance (e.g., p<0.05) whencompared to tumor volume of untreated tumor in the circumstance wherethe primary cancer therapy (e.g., chemotherapeutic or radiation therapy)alone is unable to produce a statistically significant decrease in tumorvolume compared to tumor volume of untreated tumor. This generallyapplies to tumor volume measurements made at a time when the untreatedtumor is growing log rhythmically.

The terms “response” or “responsiveness” refers to an anti-cancerresponse, e.g. in the sense of reduction of tumor size or inhibitingtumor growth. The terms can also refer to an improved prognosis, forexample, as reflected by an increased time to recurrence, which is theperiod to first recurrence censoring for second primary cancer as afirst event or death without evidence of recurrence, or an increasedoverall survival, which is the period from treatment to death from anycause. To respond or to have a response means there is a beneficialendpoint attained when exposed to a stimulus. Alternatively, a negativeor detrimental symptom is minimized, mitigated or attenuated on exposureto a stimulus. It will be appreciated that evaluating the likelihoodthat a tumor or subject will exhibit a favorable response is equivalentto evaluating the likelihood that the tumor or subject will not exhibitfavorable response (i.e., will exhibit a lack of response or benon-responsive).

An “RNA interfering agent” as used herein, is defined as any agent whichinterferes with or inhibits expression of a target biomarker gene by RNAinterference (RNAi). Such RNA interfering agents include, but are notlimited to, nucleic acid molecules including RNA molecules which arehomologous to the target biomarker gene of the present invention, or afragment thereof, short interfering RNA (siRNA), and small moleculeswhich interfere with or inhibit expression of a target biomarker nucleicacid by RNA interference (RNAi).

“RNA interference (RNAi)” is an evolutionally conserved process wherebythe expression or introduction of RNA of a sequence that is identical orhighly similar to a target biomarker nucleic acid results in thesequence specific degradation or specific post-transcriptional genesilencing (PTGS) of messenger RNA (mRNA) transcribed from that targetedgene (see Coburn and Cullen (2002) J. Virol. 76:9225), therebyinhibiting expression of the target biomarker nucleic acid. In oneembodiment, the RNA is double stranded RNA (dsRNA). This process hasbeen described in plants, invertebrates, and mammalian cells. In nature,RNAi is initiated by the dsRNA-specific endonuclease Dicer, whichpromotes processive cleavage of long dsRNA into double-strandedfragments termed siRNAs. siRNAs are incorporated into a protein complexthat recognizes and cleaves target mRNAs. RNAi can also be initiated byintroducing nucleic acid molecules, e.g., synthetic siRNAs or RNAinterfering agents, to inhibit or silence the expression of targetbiomarker nucleic acids. As used herein, “inhibition of target biomarkernucleic acid expression” or “inhibition of marker gene expression”includes any decrease in expression or protein activity or level of thetarget biomarker nucleic acid or protein encoded by the target biomarkernucleic acid. The decrease may be of at least 30%, 40%, 50%, 60%, 70%,80%, 90%, 95% or 99% or more as compared to the expression of a targetbiomarker nucleic acid or the activity or level of the protein encodedby a target biomarker nucleic acid which has not been targeted by an RNAinterfering agent.

The term “sample” used for detecting or determining the presence orlevel of at least one biomarker is typically brain tissue, cerebrospinalfluid, whole blood, plasma, serum, saliva, urine, stool (e.g., feces),tears, and any other bodily fluid (e.g., as described above under thedefinition of “body fluids”), or a tissue sample (e.g., biopsy) such asa small intestine, colon sample, or surgical resection tissue. Incertain instances, the method of the present invention further comprisesobtaining the sample from the individual prior to detecting ordetermining the presence or level of at least one marker in the sample.

The term “sensitize” means to alter cancer cells or tumor cells in a waythat allows for more effective treatment of the associated cancer with acancer therapy (e.g., anti-immune checkpoint, chemotherapeutic, and/orradiation therapy). In some embodiments, normal cells are not affectedto an extent that causes the normal cells to be unduly injured by thetherapies. An increased sensitivity or a reduced sensitivity to atherapeutic treatment is measured according to a known method in the artfor the particular treatment and methods described herein below,including, but not limited to, cell proliferative assays (Tanigawa N,Kern D H, Kikasa Y, Morton D L, Cancer Res 1982; 42: 2159-2164), celldeath assays (Weisenthal L M, Shoemaker R H, Marsden J A, Dill P L,Baker J A, Moran E M, Cancer Res 1984; 94: 161-173; Weisenthal L M,Lippman M E, Cancer Treat Rep 1985; 69: 615-632; Weisenthal L M, In:Kaspers G J L, Pieters R, Twentyman P R, Weisenthal L M, Veerman A J P,eds. Drug Resistance in Leukemia and Lymphoma. Langhorne, P A: HarwoodAcademic Publishers, 1993: 415-432; Weisenthal L M, Contrib GynecolObstet 1994; 19: 82-90). The sensitivity or resistance may also bemeasured in animal by measuring the tumor size reduction over a periodof time, for example, 6 month for human and 4-6 weeks for mouse. Acomposition or a method sensitizes response to a therapeutic treatmentif the increase in treatment sensitivity or the reduction in resistanceis 25% or more, for example, 30%, 40%, 50%, 60%, 70%, 80%, or more, to2-fold, 3-fold, 4-fold, 5-fold, 10-fold, 15-fold, 20-fold or more,compared to treatment sensitivity or resistance in the absence of suchcomposition or method. The determination of sensitivity or resistance toa therapeutic treatment is routine in the art and within the skill of anordinarily skilled clinician. It is to be understood that any methoddescribed herein for enhancing the efficacy of a cancer therapy can beequally applied to methods for sensitizing hyperproliferative orotherwise cancerous cells (e.g., resistant cells) to the cancer therapy.

“Short interfering RNA” (siRNA), also referred to herein as “smallinterfering RNA” is defined as an agent which functions to inhibitexpression of a target biomarker nucleic acid, e.g., by RNAi. An siRNAmay be chemically synthesized, may be produced by in vitrotranscription, or may be produced within a host cell. In one embodiment,siRNA is a double stranded RNA (dsRNA) molecule of about 15 to about 40nucleotides in length, preferably about 15 to about 28 nucleotides, morepreferably about 19 to about 25 nucleotides in length, and morepreferably about 19, 20, 21, or 22 nucleotides in length, and maycontain a 3′ and/or 5′ overhang on each strand having a length of about0, 1, 2, 3, 4, or 5 nucleotides. The length of the overhang isindependent between the two strands, i.e., the length of the overhang onone strand is not dependent on the length of the overhang on the secondstrand. Preferably the siRNA is capable of promoting RNA interferencethrough degradation or specific post-transcriptional gene silencing(PTGS) of the target messenger RNA (mRNA).

In another embodiment, an siRNA is a small hairpin (also called stemloop) RNA (shRNA). In one embodiment, these shRNAs are composed of ashort (e.g., 19-25 nucleotide) antisense strand, followed by a 5-9nucleotide loop, and the analogous sense strand. Alternatively, thesense strand may precede the nucleotide loop structure and the antisensestrand may follow. These shRNAs may be contained in plasmids,retroviruses, and lentiviruses and expressed from, for example, the polIII U6 promoter, or another promoter (see, e.g., Stewart, et al. (2003)RNA April; 9(4):493-501 incorporated by reference herein).

RNA interfering agents, e.g., siRNA molecules, may be administered to apatient having or at risk for having cancer, to inhibit expression of abiomarker gene which is overexpressed in cancer and thereby treat,prevent, or inhibit cancer in the subject.

The term “small molecule” is a term of the art and includes moleculesthat are less than about 1000 molecular weight or less than about 500molecular weight. In one embodiment, small molecules do not exclusivelycomprise peptide bonds. In another embodiment, small molecules are notoligomeric. Exemplary small molecule compounds which can be screened foractivity include, but are not limited to, peptides, peptidomimetics,nucleic acids, carbohydrates, small organic molecules (e.g.,polyketides) (Cane et al. (1998) Science 282:63), and natural productextract libraries. In another embodiment, the compounds are small,organic non-peptidic compounds. In a further embodiment, a smallmolecule is not biosynthetic.

The term “specific binding” refers to antibody binding to apredetermined antigen. Typically, the antibody binds with an affinity(K_(D)) of approximately less than 10⁻⁷ M, such as approximately lessthan 10⁻⁸ M, 10⁻⁹ M or 10⁻¹⁰ M or even lower when determined by surfaceplasmon resonance (SPR) technology in a BIACORE® assay instrument usingan antigen of interest as the analyte and the antibody as the ligand,and binds to the predetermined antigen with an affinity that is at least1.1-, 1.2-, 1.3-, 1.4-, 1.5-, 1.6-, 1.7-, 1.8-, 1.9-, 2.0-, 2.5-, 3.0-,3.5-, 4.0-, 4.5-, 5.0-, 6.0-, 7.0-, 8.0-, 9.0-, or 10.0-fold or greaterthan its affinity for binding to a non-specific antigen (e.g., BSA,casein) other than the predetermined antigen or a closely-relatedantigen. The phrases “an antibody recognizing an antigen” and “anantibody specific for an antigen” are used interchangeably herein withthe term “an antibody which binds specifically to an antigen.” Selectivebinding is a relative term referring to the ability of an antibody todiscriminate the binding of one antigen over another.

The term “subject” refers to any healthy animal, mammal or human, or anyanimal, mammal or human afflicted with a cancer, e.g., brain, lung,ovarian, pancreatic, liver, breast, prostate, and/or colorectal cancers,melanoma, multiple myeloma, and the like. The term “subject” isinterchangeable with “patient.”

The term “survival” includes all of the following: survival untilmortality, also known as overall survival (wherein said mortality may beeither irrespective of cause or tumor related); “recurrence-freesurvival” (wherein the term recurrence shall include both localized anddistant recurrence); metastasis free survival; disease free survival(wherein the term disease shall include cancer and diseases associatedtherewith). The length of said survival may be calculated by referenceto a defined start point (e.g. time of diagnosis or start of treatment)and end point (e.g. death, recurrence or metastasis). In addition,criteria for efficacy of treatment can be expanded to include responseto chemotherapy, probability of survival, probability of metastasiswithin a given time period, and probability of tumor recurrence.

The term “synergistic effect” refers to the combined effect of two ormore anti-cancer agents (e.g., modulator of genomic and/or epigenomicalterations of one or more biomarkers listed in Tables1A-D/immunotherapy combination therapy) can be greater than the sum ofthe separate effects of the anti-cancer agents/therapies alone.

The term “T cell” includes CD4⁺ T cells and CD8⁺ T cells. The term Tcell also includes both T helper 1 type T cells and T helper 2 type Tcells. The term “antigen presenting cell” includes professional antigenpresenting cells (e.g., B lymphocytes, monocytes, dendritic cells,Langerhans cells), as well as other antigen presenting cells (e.g.,keratinocytes, endothelial cells, astrocytes, fibroblasts, andoligodendrocytes).

The term “therapeutic effect” refers to a local or systemic effect inanimals, particularly mammals, and more particularly humans, caused by apharmacologically active substance. The term thus means any substanceintended for use in the diagnosis, cure, mitigation, treatment orprevention of disease or in the enhancement of desirable physical ormental development and conditions in an animal or human. The phrase“therapeutically-effective amount” means that amount of such a substancethat produces some desired local or systemic effect at a reasonablebenefit/risk ratio applicable to any treatment. In certain embodiments,a therapeutically effective amount of a compound will depend on itstherapeutic index, solubility, and the like. For example, certaincompounds discovered by the methods of the present invention may beadministered in a sufficient amount to produce a reasonable benefit/riskratio applicable to such treatment.

The terms “therapeutically-effective amount” and “effective amount” asused herein means that amount of a compound, material, or compositioncomprising a compound of the present invention which is effective forproducing some desired therapeutic effect in at least a sub-populationof cells in an animal at a reasonable benefit/risk ratio applicable toany medical treatment. Toxicity and therapeutic efficacy of subjectcompounds may be determined by standard pharmaceutical procedures incell cultures or experimental animals, e.g., for determining the LD₅₀and the ED₅₀. Compositions that exhibit large therapeutic indices arepreferred. In some embodiments, the LD₅₀ (lethal dosage) can be measuredand can be, for example, at least 10%, 20%, 30%, 40%, 50%, 60%, 70%,80%, 90%, 100%, 200%, 300%, 400%, 500%, 600%, 700%, 800%, 900%, 1000% ormore reduced for the agent relative to no administration of the agent.Similarly, the ED₅₀ (i.e., the concentration which achieves ahalf-maximal inhibition of symptoms) can be measured and can be, forexample, at least 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 100%,200%, 300%, 400%, 500%, 600%, 700%, 800%, 900%, 1000% or more increasedfor the agent relative to no administration of the agent. Also,Similarly, the IC₅₀ (i.e., the concentration which achieves half-maximalcytotoxic or cytostatic effect on cancer cells) can be measured and canbe, for example, at least 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%,100%, 200%, 300%, 400%, 500%, 600%, 700%, 800%, 900%, 1000% or moreincreased for the agent relative to no administration of the agent. Insome embodiments, cancer cell growth in an assay can be inhibited by atleast about 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%,70%, 75%, 80%, 85%, 90%, 95%, or even 100%. In another embodiment, atleast about a 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%,65%, 70%, 75%, 80%, 85%, 90%, 95%, or even 100% decrease in a solidmalignancy can be achieved.

A “transcribed polynucleotide” or “nucleotide transcript” is apolynucleotide (e.g. an mRNA, hnRNA, a cDNA, or an analog of such RNA orcDNA) which is complementary to or homologous with all or a portion of amature mRNA made by transcription of a biomarker nucleic acid and normalpost-transcriptional processing (e.g. splicing), if any, of the RNAtranscript, and reverse transcription of the RNA transcript.

As used herein, the term “unresponsiveness” includes refractivity ofcancer cells to therapy or refractivity of therapeutic cells, such asimmune cells, to stimulation, e.g., stimulation via an activatingreceptor or a cytokine. Unresponsiveness can occur, e.g., because ofexposure to immunosuppressants or exposure to high doses of antigen. Asused herein, the term “anergy” or “tolerance” includes refractivity toactivating receptor-mediated stimulation. Such refractivity is generallyantigen-specific and persists after exposure to the tolerizing antigenhas ceased. For example, anergy in T cells (as opposed tounresponsiveness) is characterized by lack of cytokine production, e.g.,IL-2. T cell anergy occurs when T cells are exposed to antigen andreceive a first signal (a T cell receptor or CD-3 mediated signal) inthe absence of a second signal (a costimulatory signal). Under theseconditions, reexposure of the cells to the same antigen (even ifreexposure occurs in the presence of a costimulatory polypeptide)results in failure to produce cytokines and, thus, failure toproliferate. Anergic T cells can, however, proliferate if cultured withcytokines (e.g., IL-2). For example, T cell anergy can also be observedby the lack of IL-2 production by T lymphocytes as measured by ELISA orby a proliferation assay using an indicator cell line. Alternatively, areporter gene construct can be used. For example, anergic T cells failto initiate IL-2 gene transcription induced by a heterologous promoterunder the control of the 5′ IL-2 gene enhancer or by a multimer of theAP1 sequence that can be found within the enhancer (Kang et al. (1992)Science 257:1134).

There is a known and definite correspondence between the amino acidsequence of a particular protein and the nucleotide sequences that cancode for the protein, as defined by the genetic code (shown below).Likewise, there is a known and definite correspondence between thenucleotide sequence of a particular nucleic acid and the amino acidsequence encoded by that nucleic acid, as defined by the genetic code.

GENETIC CODE Alanine (Ala, A) GCA, GCC, GCG, GCT Arginine (Arg, R)AGA, ACG, CGA, CGC, CGG, CGT Asparagine (Asn, N) AAC, AATAspartic acid (Asp, GAC, GAT D) Cysteine (Cys, C) TGC, TGTGlutamic acid (Glu, GAA, GAG E) Glutamine (Gln, Q) CAA, CAGGlycine (Gly, G) GGA, GGC, GGG, GGT Histidine (His, H) CAC, CATIsoleucine (Ile, I) ATA, ATC, ATT Leucine (Leu, L)CTA, CTC, CTG, CTT, TTA, TTG Lysine (Lys, K) AAA, AAGMethionine (Met, M) ATG Phenylalanine (Phe, TTC, TTT F) Proline (Pro, P)CCA, CCC, CCG, CCT Serine (Ser, S) AGC, AGT, TCA, TCC, TCG, TCTThreonine (Thr, T) ACA, ACC, ACG, ACT Tryptophan (Trp, W) TGGTyrosine (Tyr, Y) TAC, TAT Valine (Val, V) GTA, GTC, GTG, GTTTermination signal TAA, TAG, TGA (end)

An important and well-known feature of the genetic code is itsredundancy, whereby, for most of the amino acids used to make proteins,more than one coding nucleotide triplet may be employed (illustratedabove). Therefore, a number of different nucleotide sequences may codefor a given amino acid sequence. Such nucleotide sequences areconsidered functionally equivalent since they result in the productionof the same amino acid sequence in all organisms (although certainorganisms may translate some sequences more efficiently than they doothers). Moreover, occasionally, a methylated variant of a purine orpyrimidine may be found in a given nucleotide sequence. Suchmethylations do not affect the coding relationship between thetrinucleotide codon and the corresponding amino acid.

In view of the foregoing, the nucleotide sequence of a DNA or RNAencoding a biomarker nucleic acid (or any portion thereof) can be usedto derive the polypeptide amino acid sequence, using the genetic code totranslate the DNA or RNA into an amino acid sequence. Likewise, forpolypeptide amino acid sequence, corresponding nucleotide sequences thatcan encode the polypeptide can be deduced from the genetic code (which,because of its redundancy, will produce multiple nucleic acid sequencesfor any given amino acid sequence). Thus, description and/or disclosureherein of a nucleotide sequence which encodes a polypeptide should beconsidered to also include description and/or disclosure of the aminoacid sequence encoded by the nucleotide sequence. Similarly, descriptionand/or disclosure of a polypeptide amino acid sequence herein should beconsidered to also include description and/or disclosure of all possiblenucleotide sequences that can encode the amino acid sequence.

Finally, nucleic acid and amino acid sequence information for the lociand biomarkers of the present invention (e.g., biomarkers listed inTables 1A-1D) are well-known in the art and readily available onpublicly available databases, such as the National Center forBiotechnology Information (NCBI).

TABLE 1A TP53 RB1 CYLDSEQ ID NO: 1 Human TP53 Isoform a Amino Acid Sequence (NP_000537.3,NP_001119584.1) 1meepqsdpsv epplsqetfs dlwkllpenn vlsplpsqam ddlmlspddi eqwftedpgp 61deaprmpeaa ppvapapaap tpaapapaps wplsssvpsq ktyqgsygfr lgflhsgtak 121svtctyspal nkmfcqlakt cpvqlwvdst pppgtrvram aiykqsqhmt evvrrcphhe 181rcsdsdglap pqhlirvegn lrveylddrn tfrhsvvvpy eppevgsdct tihynymcns 241scmggmnrrp iltiitleds sgnllgrnsf evrvcacpgr drrteeenlr kkgephhelp 301pgstkralpn ntssspqpkk kpldgeyftl qirgrerfem frelnealel kdaqagkepg 361gsrahsshlk skkgqstsrh kklmfktegp dsdSEQ ID NO: 2 Human TP53 transcript variant 1 cDNA sequence (NM_000546.5;CDS: 203-1384) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc 301ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg 361gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt 421ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct 481gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt 541cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat 601gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc 661cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt 721gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca 781tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg 841acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca 901ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac 961catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg 1021tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg 1081ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag 1141ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcagatccg 1201tgggcgtgag cgcttcgaga tgttccgaga gctgaatgag gccttggaac tcaaggatgc 1261ccaggctggg aaggagccag gggggagcag ggctcactcc agccacctga agtccaaaaa 1321gggtcagtct acctcccgcc ataaaaaact catgttcaag acagaagggc ctgactcaga 1381ctgacattct ccacttcttg ttccccactg acagcctccc acccccatct ctccctcccc 1441tgccattttg ggttttgggt ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac 1501ccaggacttc catttgcttt gtcccggggc tccactgaac aagttggcct gcactggtgt 1561tttgttgtgg ggaggaggat ggggagtagg acataccagc ttagatttta aggtttttac 1621tgtgagggat gtttgggaga tgtaagaaat gttcttgcag ttaagggtta gtttacaatc 1681agccacattc taggtagggg cccacttcac cgtactaacc agggaagctg tccctcactg 1741ttgaattttc tctaacttca aggcccatat ctgtgaaatg ctggcatttg cacctacctc 1801acagagtgca ttgtgagggt taatgaaata atgtacatct ggccttgaaa ccacctttta 1861ttacatgggg tctagaactt gacccccttg agggtgcttg ttccctctcc ctgttggtcg 1921gtgggttggt agtttctaca gttgggcagc tggttaggta gagggagttg tcaagtctct 1981gctggcccag ccaaaccctg tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa 2041tctcacccca tcccacaccc tggaggattt catctcttgt atatgatgat ctggatccac 2101caagacttgt tttatgctca gggtcaattt cttttttctt tttttttttt ttttttcttt 2161ttctttgaga ctgggtctcg ctttgttgcc caggctggag tggagtggcg tgatcttggc 2221ttactgcagc ctttgcctcc ccggctcgag cagtcctgcc tcagcctccg gagtagctgg 2281gaccacaggt tcatgccacc atggccagcc aacttttgca tgttttgtag agatggggtc 2341tcacagtgtt gcccaggctg gtctcaaact cctgggctca ggcgatccac ctgtctcagc 2401ctcccagagt gctgggatta caattgtgag ccaccacgtc cagctggaag ggtcaacatc 2461ttttacattc tgcaagcaca tctgcatttt caccccaccc ttcccctcct tctccctttt 2521tatatcccat ttttatatcg atctcttatt ttacaataaa actttgctgc cacctgtgtg 2581tctgaggggt g SEQ ID NO: 3 Human TP53 transcript variant 2 cDNA sequence(NM_001126112.2; CDS: 200-1381) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggccagac 181tgccttccgg gtcactgcca tggaggagcc gcagtcagat cctagcgtcg agccccctct 241gagtcaggaa acattttcag acctatggaa actacttcct gaaaacaacg ttctgtcccc 301cttgccgtcc caagcaatgg atgatttgat gctgtccccg gacgatattg aacaatggtt 361cactgaagac ccaggtccag atgaagctcc cagaatgcca gaggctgctc cccccgtggc 421ccctgcacca gcagctccta caccggcggc ccctgcacca gccccctcct ggcccctgtc 481atcttctgtc ccttcccaga aaacctacca gggcagctac ggtttccgtc tgggcttctt 541gcattctggg acagccaagt ctgtgacttg cacgtactcc cctgccctca acaagatgtt 601ttgccaactg gccaagacct gccctgtgca gctgtgggtt gattccacac ccccgcccgg 661cacccgcgtc cgcgccatgg ccatctacaa gcagtcacag cacatgacgg aggttgtgag 721gcgctgcccc caccatgagc gctgctcaga tagcgatggt ctggcccctc ctcagcatct 781tatccgagtg gaaggaaatt tgcgtgtgga gtatttggat gacagaaaca cttttcgaca 841tagtgtggtg gtgccctatg agccgcctga ggttggctct gactgtacca ccatccacta 901caactacatg tgtaacagtt cctgcatggg cggcatgaac cggaggccca tcctcaccat 961catcacactg gaagactcca gtggtaatct actgggacgg aacagctttg aggtgcgtgt 1021ttgtgcctgt cctgggagag accggcgcac agaggaagag aatctccgca agaaagggga 1081gcctcaccac gagctgcccc cagggagcac taagcgagca ctgcccaaca acaccagctc 1141ctctccccag ccaaagaaga aaccactgga tggagaatat ttcacccttc agatccgtgg 1201gcgtgagcgc ttcgagatgt tccgagagct gaatgaggcc ttggaactca aggatgccca 1261ggctgggaag gagccagggg ggagcagggc tcactccagc cacctgaagt ccaaaaaggg 1321tcagtctacc tcccgccata aaaaactcat gttcaagaca gaagggcctg actcagactg 1381acattctcca cttcttgttc cccactgaca gcctcccacc cccatctctc cctcccctgc 1441cattttgggt tttgggtctt tgaacccttg cttgcaatag gtgtgcgtca gaagcaccca 1501ggacttccat ttgctttgtc ccggggctcc actgaacaag ttggcctgca ctggtgtttt 1561gttgtgggga ggaggatggg gagtaggaca taccagctta gattttaagg tttttactgt 1621gagggatgtt tgggagatgt aagaaatgtt cttgcagtta agggttagtt tacaatcagc 1681cacattctag gtaggggccc acttcaccgt actaaccagg gaagctgtcc ctcactgttg 1741aattttctct aacttcaagg cccatatctg tgaaatgctg gcatttgcac ctacctcaca 1801gagtgcattg tgagggttaa tgaaataatg tacatctggc cttgaaacca ccttttatta 1861catggggtct agaacttgac ccccttgagg gtgcttgttc cctctccctg ttggtcggtg 1921ggttggtagt ttctacagtt gggcagctgg ttaggtagag ggagttgtca agtctctgct 1981ggcccagcca aaccctgtct gacaacctct tggtgaacct tagtacctaa aaggaaatct 2041caccccatcc cacaccctgg aggatttcat ctcttgtata tgatgatctg gatccaccaa 2101gacttgtttt atgctcaggg tcaatttctt ttttcttttt tttttttttt tttctttttc 2161tttgagactg ggtctcgctt tgttgcccag gctggagtgg agtggcgtga tcttggctta 2221ctgcagcctt tgcctccccg gctcgagcag tcctgcctca gcctccggag tagctgggac 2281cacaggttca tgccaccatg gccagccaac ttttgcatgt tttgtagaga tggggtctca 2341cagtgttgcc caggctggtc tcaaactcct gggctcaggc gatccacctg tctcagcctc 2401ccagagtgct gggattacaa ttgtgagcca ccacgtccag ctggaagggt caacatcttt 2461tacattctgc aagcacatct gcattttcac cccacccttc ccctccttct ccctttttat 2521atcccatttt tatatcgatc tcttatttta caataaaact ttgctgccac ctgtgtgtct 2581gaggggtgSEQ ID NO: 4 Human TP53 isoform b Amino Acid Sequence (NP_001119586.1) 1meepqsdpsv epplsqetfs dlwkllpenn vlsplpsqam ddlmlspddi eqwftedpgp 61deaprmpeaa ppvapapaap tpaapapaps wplsssvpsq ktyqgsygfr lgflhsgtak 121svtctyspal nkmfcqlakt cpvqlwvdst pppgtrvram aiykqsqhmt evvrrcphhe 181rcsdsdglap pqhlirvegn lrveylddrn tfrhsvvvpy eppevgsdct tihynymcns 241scmggmnrrp iltiitleds sgnllgrnsf evrvcacpgr drrteeenlr kkgephhelp 301pgstkralpn ntssspqpkk kpldgeyftl qdqtsfqken cSEQ ID NO: 5 Human TP53 transcript variant 3 cDNA sequence(NM_001126114.2; CDS: 203-1228) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc 301ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg 361gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt 421ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct 481gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt 541cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat 601gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc 661cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt 721gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca 781tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg 841acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca 901ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac 961catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg 1021tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg 1081ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag 1141ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcaggacca 1201gaccagcttt caaaaagaaa attgttaaag agagcatgaa aatggttcta tgactttgcc 1261tgatacagat gctacttgac ttacgatggt gttacttcct gataaactcg tcgtaagttg 1321aaaatattat ccgtgggcgt gagcgcttcg agatgttccg agagctgaat gaggccttgg 1381aactcaagga tgcccaggct gggaaggagc caggggggag cagggctcac tccagccacc 1441tgaagtccaa aaagggtcag tctacctccc gccataaaaa actcatgttc aagacagaag 1501ggcctgactc agactgacat tctccacttc ttgttcccca ctgacagcct cccaccccca 1561tctctccctc ccctgccatt ttgggttttg ggtctttgaa cccttgcttg caataggtgt 1621gcgtcagaag cacccaggac ttccatttgc tttgtcccgg ggctccactg aacaagttgg 1681cctgcactgg tgttttgttg tggggaggag gatggggagt aggacatacc agcttagatt 1741ttaaggtttt tactgtgagg gatgtttggg agatgtaaga aatgttcttg cagttaaggg 1801ttagtttaca atcagccaca ttctaggtag gggcccactt caccgtacta accagggaag 1861ctgtccctca ctgttgaatt ttctctaact tcaaggccca tatctgtgaa atgctggcat 1921ttgcacctac ctcacagagt gcattgtgag ggttaatgaa ataatgtaca tctggccttg 1981aaaccacctt ttattacatg gggtctagaa cttgaccccc ttgagggtgc ttgttccctc 2041tccctgttgg tcggtgggtt ggtagtttct acagttgggc agctggttag gtagagggag 2101ttgtcaagtc tctgctggcc cagccaaacc ctgtctgaca acctcttggt gaaccttagt 2161acctaaaagg aaatctcacc ccatcccaca ccctggagga tttcatctct tgtatatgat 2221gatctggatc caccaagact tgttttatgc tcagggtcaa tttctttttt cttttttttt 2281tttttttttc tttttctttg agactgggtc tcgctttgtt gcccaggctg gagtggagtg 2341gcgtgatctt ggcttactgc agcctttgcc tccccggctc gagcagtcct gcctcagcct 2401ccggagtagc tgggaccaca ggttcatgcc accatggcca gccaactttt gcatgttttg 2461tagagatggg gtctcacagt gttgcccagg ctggtctcaa actcctgggc tcaggcgatc 2521cacctgtctc agcctcccag agtgctggga ttacaattgt gagccaccac gtccagctgg 2581aagggtcaac atcttttaca ttctgcaagc acatctgcat tttcacccca cccttcccct 2641ccttctccct ttttatatcc catttttata tcgatctctt attttacaat aaaactttgc 2701tgccacctgt gtgtctgagg ggtgSEQ ID NO: 6 Human TP53 isoform c Amino Acid Sequence (NP_001119585.1) 1meepqsdpsv epplsqetfs dlwkllpenn vlsplpsqam ddlmlspddi eqwftedpgp 61deaprmpeaa ppvapapaap tpaapapaps wplsssvpsq ktyqgsygfr lgflhsgtak 121svtctyspal nkmfcqlakt cpvqlwvdst pppgtrvram aiykqsqhmt evvrrcphhe 181rcsdsdglap pqhlirvegn lrveylddrn tfrhsvvvpy eppevgsdct tihynymcns 241scmggmnrrp iltiitleds sgnllgrnsf evrvcacpgr drrteeenlr kkgephhelp 301pgstkralpn ntssspqpkk kpldgeyftl qmlldlrwcy flinssSEQ ID NO: 7 Human TP53 transcript variant 4 cDNA sequence(NM_001126113.2; CDS: 203-1243) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc 301ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg 361gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt 421ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct 481gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt 541cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat 601gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc 661cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt 721gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca 781tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg 841acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca 901ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac 961catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg 1021tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg 1081ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag 1141ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcagatgct 1201acttgactta cgatggtgtt acttcctgat aaactcgtcg taagttgaaa atattatccg 1261tgggcgtgag cgcttcgaga tgttccgaga gctgaatgag gccttggaac tcaaggatgc 1321ccaggctggg aaggagccag gggggagcag ggctcactcc agccacctga agtccaaaaa 1381gggtcagtct acctcccgcc ataaaaaact catgttcaag acagaagggc ctgactcaga 1441ctgacattct ccacttcttg ttccccactg acagcctccc acccccatct ctccctcccc 1501tgccattttg ggttttgggt ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac 1561ccaggacttc catttgcttt gtcccggggc tccactgaac aagttggcct gcactggtgt 1621tttgttgtgg ggaggaggat ggggagtagg acataccagc ttagatttta aggtttttac 1681tgtgagggat gtttgggaga tgtaagaaat gttcttgcag ttaagggtta gtttacaatc 1741agccacattc taggtagggg cccacttcac cgtactaacc agggaagctg tccctcactg 1801ttgaattttc tctaacttca aggcccatat ctgtgaaatg ctggcatttg cacctacctc 1861acagagtgca ttgtgagggt taatgaaata atgtacatct ggccttgaaa ccacctttta 1921ttacatgggg tctagaactt gacccccttg agggtgcttg ttccctctcc ctgttggtcg 1981gtgggttggt agtttctaca gttgggcagc tggttaggta gagggagttg tcaagtctct 2041gctggcccag ccaaaccctg tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa 2101tctcacccca tcccacaccc tggaggattt catctcttgt atatgatgat ctggatccac 2161caagacttgt tttatgctca gggtcaattt cttttttctt tttttttttt ttttttcttt 2221ttctttgaga ctgggtctcg ctttgttgcc caggctggag tggagtggcg tgatcttggc 2281ttactgcagc ctttgcctcc ccggctcgag cagtcctgcc tcagcctccg gagtagctgg 2341gaccacaggt tcatgccacc atggccagcc aacttttgca tgttttgtag agatggggtc 2401tcacagtgtt gcccaggctg gtctcaaact cctgggctca ggcgatccac ctgtctcagc 2461ctcccagagt gctgggatta caattgtgag ccaccacgtc cagctggaag ggtcaacatc 2521ttttacattc tgcaagcaca tctgcatttt caccccaccc ttcccctcct tctccctttt 2581tatatcccat ttttatatcg atctcttatt ttacaataaa actttgctgc cacctgtgtg 2641tctgaggggt gSEQ ID NO: 8 Human TP53 isoform d Amino Acid Sequence (NP_001119587.1) 1mfcqlaktcp vqlwvdstpp pgtrvramai ykqsqhmtev vrrcphherc sdsdglappq 61hlirvegnlr veylddrntf rhsvvvpyep pevgsdctti hynymcnssc mggmnrrpil 121tiitledssg nllgrnsfev rvcacpgrdr rteeenlrkk gephhelppg stkralpnnt 181ssspqpkkkp ldgeyftlqi rgrerfemfr elnealelkd aqagkepggs rahsshlksk 241kgqstsrhkk lmfktegpds dSEQ ID NO: 9 Human TP53 transcript variant 5 cDNA sequence(NM_001126115.1; CDS: 279-1064) 1tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag 61tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag 121acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct 181ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct 241ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga 301cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca 361tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg 421agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa 481atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct 541atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca 601gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact 661ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga 721gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc 781ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga 841agaaaccact ggatggagaa tatttcaccc ttcagatccg tgggcgtgag cgcttcgaga 901tgttccgaga gctgaatgag gccttggaac tcaaggatgc ccaggctggg aaggagccag 961gggggagcag ggctcactcc agccacctga agtccaaaaa gggtcagtct acctcccgcc 1021ataaaaaact catgttcaag acagaagggc ctgactcaga ctgacattct ccacttcttg 1081ttccccactg acagcctccc acccccatct ctccctcccc tgccattttg ggttttgggt 1141ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac ccaggacttc catttgcttt 1201gtcccggggc tccactgaac aagttggcct gcactggtgt tttgttgtgg ggaggaggat 1261ggggagtagg acataccagc ttagatttta aggtttttac tgtgagggat gtttgggaga 1321tgtaagaaat gttcttgcag ttaagggtta gtttacaatc agccacattc taggtagggg 1381cccacttcac cgtactaacc agggaagctg tccctcactg ttgaattttc tctaacttca 1441aggcccatat ctgtgaaatg ctggcatttg cacctacctc acagagtgca ttgtgagggt 1501taatgaaata atgtacatct ggccttgaaa ccacctttta ttacatgggg tctagaactt 1561gacccccttg agggtgcttg ttccctctcc ctgttggtcg gtgggttggt agtttctaca 1621gttgggcagc tggttaggta gagggagttg tcaagtctct gctggcccag ccaaaccctg 1681tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa tctcacccca tcccacaccc 1741tggaggattt catctcttgt atatgatgat ctggatccac caagacttgt tttatgctca 1801gggtcaattt cttttttctt tttttttttt ttttttcttt ttctttgaga ctgggtctcg 1861ctttgttgcc caggctggag tggagtggcg tgatcttggc ttactgcagc ctttgcctcc 1921ccggctcgag cagtcctgcc tcagcctccg gagtagctgg gaccacaggt tcatgccacc 1981atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctg 2041gtctcaaact cctgggctca ggcgatccac ctgtctcagc ctcccagagt gctgggatta 2101caattgtgag ccaccacgtc cagctggaag ggtcaacatc ttttacattc tgcaagcaca 2161tctgcatttt caccccaccc ttcccctcct tctccctttt tatatcccat ttttatatcg 2221atctcttatt ttacaataaa actttgctgc cacctgtgtg tctgaggggt g 1981atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctgSEQ ID NO: 10 Human TP53 isoform e Amino Acid Sequence (NP_001119588.1)1 mfcqlaktcp vqlwvdstpp pgtrvramai ykqsqhmtev vrrcphherc sdsdglappq 61hlirvegnlr veylddrntf rhsvvvpyep pevgsdctti hynymcnssc mggmnrrpil 121tiitledssg nllgrnsfev rvcacpgrdr rteeenlrkk gephhelppg stkralpnnt 181ssspqpkkkp ldgeyftlqd qtsfqkencSEQ ID NO: 11 Human TP53 transcript variant 6 cDNA sequence(NM_001126116.1; CDS: 279-908) 1tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag 61tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag 121acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct 181ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct 241ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga 301cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca 361tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg 421agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa 481atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct 541atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca 601gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact 661ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga 721gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc 781ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga 841agaaaccact ggatggagaa tatttcaccc ttcaggacca gaccagcttt caaaaagaaa 901attgttaaag agagcatgaa aatggttcta tgactttgcc tgatacagat gctacttgac 961ttacgatggt gttacttcct gataaactcg tcgtaagttg aaaatattat ccgtgggcgt 1021gagcgcttcg agatgttccg agagctgaat gaggccttgg aactcaagga tgcccaggct 1081gggaaggagc caggggggag cagggctcac tccagccacc tgaagtccaa aaagggtcag 1141tctacctccc gccataaaaa actcatgttc aagacagaag ggcctgactc agactgacat 1201tctccacttc ttgttcccca ctgacagcct cccaccccca tctctccctc ccctgccatt 1261ttgggttttg ggtctttgaa cccttgcttg caataggtgt gcgtcagaag cacccaggac 1321ttccatttgc tttgtcccgg ggctccactg aacaagttgg cctgcactgg tgttttgttg 1381tggggaggag gatggggagt aggacatacc agcttagatt ttaaggtttt tactgtgagg 1441gatgtttggg agatgtaaga aatgttcttg cagttaaggg ttagtttaca atcagccaca 1501ttctaggtag gggcccactt caccgtacta accagggaag ctgtccctca ctgttgaatt 1561ttctctaact tcaaggccca tatctgtgaa atgctggcat ttgcacctac ctcacagagt 1621gcattgtgag ggttaatgaa ataatgtaca tctggccttg aaaccacctt ttattacatg 1681gggtctagaa cttgaccccc ttgagggtgc ttgttccctc tccctgttgg tcggtgggtt 1741ggtagtttct acagttgggc agctggttag gtagagggag ttgtcaagtc tctgctggcc 1801cagccaaacc ctgtctgaca acctcttggt gaaccttagt acctaaaagg aaatctcacc 1861ccatcccaca ccctggagga tttcatctct tgtatatgat gatctggatc caccaagact 1921tgttttatgc tcagggtcaa tttctttttt cttttttttt tttttttttc tttttctttg 1981agactgggtc tcgctttgtt gcccaggctg gagtggagtg gcgtgatctt ggcttactgc 2041agcctttgcc tccccggctc gagcagtcct gcctcagcct ccggagtagc tgggaccaca 2101ggttcatgcc accatggcca gccaactttt gcatgttttg tagagatggg gtctcacagt 2161gttgcccagg ctggtctcaa actcctgggc tcaggcgatc cacctgtctc agcctcccag 2221agtgctggga ttacaattgt gagccaccac gtccagctgg aagggtcaac atcttttaca 2281ttctgcaagc acatctgcat tttcacccca cccttcccct ccttctccct ttttatatcc 2341catttttata tcgatctctt attttacaat aaaactttgc tgccacctgt gtgtctgagg 2401ggtgSEQ ID NO: 12 Human TP53 isoform f Amino Acid Sequence (NP_001119589.1)1 mfcqlaktcp vqlwvdstpp pgtrvramai ykqsqhmtev vrrcphherc sdsdglappq 61hlirvegnlr veylddrntf rhsvvvpyep pevgsdctti hynymcnssc mggmnrrpil 121tiitledssg nllgrnsfev rvcacpgrdr rteeenlrkk gephhelppg stkralpnnt 181ssspqpkkkp ldgeyftlqm lldlrwcyfl inssSEQ ID NO: 13 Human TP53 transcript variant 7 cDNA sequence(NM_001126117.1; CDS: 279-923) 1tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag 61tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag 121acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct 181ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct 241ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga 301cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca 361tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg 421agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa 481atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct 541atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca 601gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact 661ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga 721gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc 781ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga 841agaaaccact ggatggagaa tatttcaccc ttcagatgct acttgactta cgatggtgtt 901acttcctgat aaactcgtcg taagttgaaa atattatccg tgggcgtgag cgcttcgaga 961tgttccgaga gctgaatgag gccttggaac tcaaggatgc ccaggctggg aaggagccag 1021gggggagcag ggctcactcc agccacctga agtccaaaaa gggtcagtct acctcccgcc 1081ataaaaaact catgttcaag acagaagggc ctgactcaga ctgacattct ccacttcttg 1141ttccccactg acagcctccc acccccatct ctccctcccc tgccattttg ggttttgggt 1201ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac ccaggacttc catttgcttt 1261gtcccggggc tccactgaac aagttggcct gcactggtgt tttgttgtgg ggaggaggat 1321ggggagtagg acataccagc ttagatttta aggtttttac tgtgagggat gtttgggaga 1381tgtaagaaat gttcttgcag ttaagggtta gtttacaatc agccacattc taggtagggg 1441cccacttcac cgtactaacc agggaagctg tccctcactg ttgaattttc tctaacttca 1501aggcccatat ctgtgaaatg ctggcatttg cacctacctc acagagtgca ttgtgagggt 1561taatgaaata atgtacatct ggccttgaaa ccacctttta ttacatgggg tctagaactt 1621gacccccttg agggtgcttg ttccctctcc ctgttggtcg gtgggttggt agtttctaca 1681gttgggcagc tggttaggta gagggagttg tcaagtctct gctggcccag ccaaaccctg 1741tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa tctcacccca tcccacaccc 1801tggaggattt catctcttgt atatgatgat ctggatccac caagacttgt tttatgctca 1861gggtcaattt cttttttctt tttttttttt ttttttcttt ttctttgaga ctgggtctcg 1921ctttgttgcc caggctggag tggagtggcg tgatcttggc ttactgcagc ctttgcctcc 1981ccggctcgag cagtcctgcc tcagcctccg gagtagctgg gaccacaggt tcatgccacc 2041atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctg 2101gtctcaaact cctgggctca ggcgatccac ctgtctcagc ctcccagagt gctgggatta 2161caattgtgag ccaccacgtc cagctggaag ggtcaacatc ttttacattc tgcaagcaca 2221tctgcatttt caccccaccc ttcccctcct tctccctttt tatatcccat ttttatatcg 2281atctcttatt ttacaataaa actttgctgc cacctgtgtg tctgaggggt gSEQ ID NO: 14 Human TP53 isoform g Amino Acid Sequence (NP_001119590.1,NP_001263689,1, and NP_001263690.1) 1mddlmlspdd ieqwftedpg pdeaprmpea appvapapaa ptpaapapap swplsssvps 61qktyqgsygf rlgflhsgta ksvtctyspa lnkmfcqlak tcpvqlwvds tpppgtrvra 121maiykqsqhm tevvrrcphh ercsdsdgla ppqhlirveg nlrveylddr ntfrhsvvvp 181yeppevgsdc ttihynymcn sscmggmnrr piltiitled ssgnllgrns fevrvcacpg 241rdrrteeenl rkkgephhel ppgstkralp nntssspqpk kkpldgeyft lqirgrerfe 301mfrelneale lkdaqagkep ggsrahsshl kskkgqstsr hkklmfkteg pdsdSEQ ID NO: 15 Human TP53 transcript variant 8 cDNA sequence(NM_001126118.1; CDS: 437-1501) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactgtga gtggatccat tggaagggca 301ggcccaccac ccccacccca accccagccc cctagcagag acctgtggga agcgaaaatt 361ccatgggact gactttctgc tcttgtcttt cagacttcct gaaaacaacg ttctgtcccc 421cttgccgtcc caagcaatgg atgatttgat gctgtccccg gacgatattg aacaatggtt 481cactgaagac ccaggtccag atgaagctcc cagaatgcca gaggctgctc cccccgtggc 541ccctgcacca gcagctccta caccggcggc ccctgcacca gccccctcct ggcccctgtc 601atcttctgtc ccttcccaga aaacctacca gggcagctac ggtttccgtc tgggcttctt 661gcattctggg acagccaagt ctgtgacttg cacgtactcc cctgccctca acaagatgtt 721ttgccaactg gccaagacct gccctgtgca gctgtgggtt gattccacac ccccgcccgg 781cacccgcgtc cgcgccatgg ccatctacaa gcagtcacag cacatgacgg aggttgtgag 841gcgctgcccc caccatgagc gctgctcaga tagcgatggt ctggcccctc ctcagcatct 901tatccgagtg gaaggaaatt tgcgtgtgga gtatttggat gacagaaaca cttttcgaca 961tagtgtggtg gtgccctatg agccgcctga ggttggctct gactgtacca ccatccacta 1021caactacatg tgtaacagtt cctgcatggg cggcatgaac cggaggccca tcctcaccat 1081catcacactg gaagactcca gtggtaatct actgggacgg aacagctttg aggtgcgtgt 1141ttgtgcctgt cctgggagag accggcgcac agaggaagag aatctccgca agaaagggga 1201gcctcaccac gagctgcccc cagggagcac taagcgagca ctgcccaaca acaccagctc 1261ctctccccag ccaaagaaga aaccactgga tggagaatat ttcacccttc agatccgtgg 1321gcgtgagcgc ttcgagatgt tccgagagct gaatgaggcc ttggaactca aggatgccca 1381ggctgggaag gagccagggg ggagcagggc tcactccagc cacctgaagt ccaaaaaggg 1441tcagtctacc tcccgccata aaaaactcat gttcaagaca gaagggcctg actcagactg 1501acattctcca cttcttgttc cccactgaca gcctcccacc cccatctctc cctcccctgc 1561cattttgggt tttgggtctt tgaacccttg cttgcaatag gtgtgcgtca gaagcaccca 1621ggacttccat ttgctttgtc ccggggctcc actgaacaag ttggcctgca ctggtgtttt 1681gttgtgggga ggaggatggg gagtaggaca taccagctta gattttaagg tttttactgt 1741gagggatgtt tgggagatgt aagaaatgtt cttgcagtta agggttagtt tacaatcagc 1801cacattctag gtaggggccc acttcaccgt actaaccagg gaagctgtcc ctcactgttg 1861aattttctct aacttcaagg cccatatctg tgaaatgctg gcatttgcac ctacctcaca 1921gagtgcattg tgagggttaa tgaaataatg tacatctggc cttgaaacca ccttttatta 1981catggggtct agaacttgac ccccttgagg gtgcttgttc cctctccctg ttggtcggtg 2041ggttggtagt ttctacagtt gggcagctgg ttaggtagag ggagttgtca agtctctgct 2101ggcccagcca aaccctgtct gacaacctct tggtgaacct tagtacctaa aaggaaatct 2161caccccatcc cacaccctgg aggatttcat ctcttgtata tgatgatctg gatccaccaa 2221gacttgtttt atgctcaggg tcaatttctt ttttcttttt tttttttttt tttctttttc 2281tttgagactg ggtctcgctt tgttgcccag gctggagtgg agtggcgtga tcttggctta 2341ctgcagcctt tgcctccccg gctcgagcag tcctgcctca gcctccggag tagctgggac 2401cacaggttca tgccaccatg gccagccaac ttttgcatgt tttgtagaga tggggtctca 2461cagtgttgcc caggctggtc tcaaactcct gggctcaggc gatccacctg tctcagcctc 2521ccagagtgct gggattacaa ttgtgagcca ccacgtccag ctggaagggt caacatcttt 2581tacattctgc aagcacatct gcattttcac cccacccttc ccctccttct ccctttttat 2641atcccatttt tatatcgatc tcttatttta caataaaact ttgctgccac ctgtgtgtct 2701gaggggtg SEQ ID NO: 16 Human TP53 transcript variant 1 cDNA Sequence(NM_001276760.1; CDS: 320-1384) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc 301ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg 361gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt 421ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct 481gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt 541cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat 601gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc 661cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt 721gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca 781tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg 841acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca 901ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac 961catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg 1021tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg 1081ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag 1141ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcagatccg 1201tgggcgtgag cgcttcgaga tgttccgaga gctgaatgag gccttggaac tcaaggatgc 1261ccaggctggg aaggagccag gggggagcag ggctcactcc agccacctga agtccaaaaa 1321gggtcagtct acctcccgcc ataaaaaact catgttcaag acagaagggc ctgactcaga 1381ctgacattct ccacttcttg ttccccactg acagcctccc acccccatct ctccctcccc 1441tgccattttg ggttttgggt ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac 1501ccaggacttc catttgcttt gtcccggggc tccactgaac aagttggcct gcactggtgt 1561tttgttgtgg ggaggaggat ggggagtagg acataccagc ttagatttta aggtttttac 1621tgtgagggat gtttgggaga tgtaagaaat gttcttgcag ttaagggtta gtttacaatc 1681agccacattc taggtagggg cccacttcac cgtactaacc agggaagctg tccctcactg 1741ttgaattttc tctaacttca aggcccatat ctgtgaaatg ctggcatttg cacctacctc 1801acagagtgca ttgtgagggt taatgaaata atgtacatct ggccttgaaa ccacctttta 1861ttacatgggg tctagaactt gacccccttg agggtgcttg ttccctctcc ctgttggtcg 1921gtgggttggt agtttctaca gttgggcagc tggttaggta gagggagttg tcaagtctct 1981gctggcccag ccaaaccctg tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa 2041tctcacccca tcccacaccc tggaggattt catctcttgt atatgatgat ctggatccac 2101caagacttgt tttatgctca gggtcaattt cttttttctt tttttttttt ttttttcttt 2161ttctttgaga ctgggtctcg ctttgttgcc caggctggag tggagtggcg tgatcttggc 2221ttactgcagc ctttgcctcc ccggctcgag cagtcctgcc tcagcctccg gagtagctgg 2281gaccacaggt tcatgccacc atggccagcc aacttttgca tgttttgtag agatggggtc 2341tcacagtgtt gcccaggctg gtctcaaact cctgggctca ggcgatccac ctgtctcagc 2401ctcccagagt gctgggatta caattgtgag ccaccacgtc cagctggaag ggtcaacatc 2461ttttacattc tgcaagcaca tctgcatttt caccccaccc ttcccctcct tctccctttt 2521tatatcccat ttttatatcg atctcttatt ttacaataaa actttgctgc cacctgtgtg 2581tctgaggggt g SEQ ID NO: 17 Human TP53 transcript variant 2 cDNA Sequence(NM_001276761.1; CDS:317-1381) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggccagac 181tgccttccgg gtcactgcca tggaggagcc gcagtcagat cctagcgtcg agccccctct 241gagtcaggaa acattttcag acctatggaa actacttcct gaaaacaacg ttctgtcccc 301cttgccgtcc caagcaatgg atgatttgat gctgtccccg gacgatattg aacaatggtt 361cactgaagac ccaggtccag atgaagctcc cagaatgcca gaggctgctc cccccgtggc 421ccctgcacca gcagctccta caccggcggc ccctgcacca gccccctcct ggcccctgtc 481atcttctgtc ccttcccaga aaacctacca gggcagctac ggtttccgtc tgggcttctt 541gcattctggg acagccaagt ctgtgacttg cacgtactcc cctgccctca acaagatgtt 601ttgccaactg gccaagacct gccctgtgca gctgtgggtt gattccacac ccccgcccgg 661cacccgcgtc cgcgccatgg ccatctacaa gcagtcacag cacatgacgg aggttgtgag 721gcgctgcccc caccatgagc gctgctcaga tagcgatggt ctggcccctc ctcagcatct 781tatccgagtg gaaggaaatt tgcgtgtgga gtatttggat gacagaaaca cttttcgaca 841tagtgtggtg gtgccctatg agccgcctga ggttggctct gactgtacca ccatccacta 901caactacatg tgtaacagtt cctgcatggg cggcatgaac cggaggccca tcctcaccat 961catcacactg gaagactcca gtggtaatct actgggacgg aacagctttg aggtgcgtgt 1021ttgtgcctgt cctgggagag accggcgcac agaggaagag aatctccgca agaaagggga 1081gcctcaccac gagctgcccc cagggagcac taagcgagca ctgcccaaca acaccagctc 1141ctctccccag ccaaagaaga aaccactgga tggagaatat ttcacccttc agatccgtgg 1201gcgtgagcgc ttcgagatgt tccgagagct gaatgaggcc ttggaactca aggatgccca 1261ggctgggaag gagccagggg ggagcagggc tcactccagc cacctgaagt ccaaaaaggg 1321tcagtctacc tcccgccata aaaaactcat gttcaagaca gaagggcctg actcagactg 1381acattctcca cttcttgttc cccactgaca gcctcccacc cccatctctc cctcccctgc 1441cattttgggt tttgggtctt tgaacccttg cttgcaatag gtgtgcgtca gaagcaccca 1501ggacttccat ttgctttgtc ccggggctcc actgaacaag ttggcctgca ctggtgtttt 1561gttgtgggga ggaggatggg gagtaggaca taccagctta gattttaagg tttttactgt 1621gagggatgtt tgggagatgt aagaaatgtt cttgcagtta agggttagtt tacaatcagc 1681cacattctag gtaggggccc acttcaccgt actaaccagg gaagctgtcc ctcactgttg 1741aattttctct aacttcaagg cccatatctg tgaaatgctg gcatttgcac ctacctcaca 1801gagtgcattg tgagggttaa tgaaataatg tacatctggc cttgaaacca ccttttatta 1861catggggtct agaacttgac ccccttgagg gtgcttgttc cctctccctg ttggtcggtg 1921ggttggtagt ttctacagtt gggcagctgg ttaggtagag ggagttgtca agtctctgct 1981ggcccagcca aaccctgtct gacaacctct tggtgaacct tagtacctaa aaggaaatct 2041caccccatcc cacaccctgg aggatttcat ctcttgtata tgatgatctg gatccaccaa 2101gacttgtttt atgctcaggg tcaatttctt ttttcttttt tttttttttt tttctttttc 2161tttgagactg ggtctcgctt tgttgcccag gctggagtgg agtggcgtga tcttggctta 2221ctgcagcctt tgcctccccg gctcgagcag tcctgcctca gcctccggag tagctgggac 2281cacaggttca tgccaccatg gccagccaac ttttgcatgt tttgtagaga tggggtctca 2341cagtgttgcc caggctggtc tcaaactcct gggctcaggc gatccacctg tctcagcctc 2401ccagagtgct gggattacaa ttgtgagcca ccacgtccag ctggaagggt caacatcttt 2461tacattctgc aagcacatct gcattttcac cccacccttc ccctccttct ccctttttat 2521atcccatttt tatatcgatc tcttatttta caataaaact ttgctgccac ctgtgtgtct 2581gaggggtgSEQ ID NO: 18 Human TP53 isoform h Amino Acid Sequence (NP_001263624.1)1 mddlmlspdd ieqwftedpg pdeaprmpea appvapapaa ptpaapapap swplsssvps 61qktyqgsygf rlgflhsgta ksvtctyspa lnkmfcqlak tcpvqlwvds tpppgtrvra 121maiykqsqhm tevvrrcphh ercsdsdgla ppqhlirveg nlrveylddr ntfrhsvvvp 181yeppevgsdc ttihynymcn sscmggmnrr piltiitled ssgnllgrns fevrvcacpg 241rdrrteeenl rkkgephhel ppgstkralp nntssspqpk kkpldgeyft lqmlldlrwc 301yflinss SEQ ID NO: 19 Human TP53 transcript variant 4 cDNA Sequence(NM_001276695.1; CDS: 320-1243) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc 301ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg 361gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt 421ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct 481gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt 541cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat 601gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc 661cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt 721gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca 781tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg 841acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca 901ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac 961catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg 1021tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg 1081ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag 1141ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcagatgct 1201acttgactta cgatggtgtt acttcctgat aaactcgtcg taagttgaaa atattatccg 1261tgggcgtgag cgcttcgaga tgttccgaga gctgaatgag gccttggaac tcaaggatgc 1321ccaggctggg aaggagccag gggggagcag ggctcactcc agccacctga agtccaaaaa 1381gggtcagtct acctcccgcc ataaaaaact catgttcaag acagaagggc ctgactcaga 1441ctgacattct ccacttcttg ttccccactg acagcctccc acccccatct ctccctcccc 1501tgccattttg ggttttgggt ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac 1561ccaggacttc catttgcttt gtcccggggc tccactgaac aagttggcct gcactggtgt 1621tttgttgtgg ggaggaggat ggggagtagg acataccagc ttagatttta aggtttttac 1681tgtgagggat gtttgggaga tgtaagaaat gttcttgcag ttaagggtta gtttacaatc 1741agccacattc taggtagggg cccacttcac cgtactaacc agggaagctg tccctcactg 1801ttgaattttc tctaacttca aggcccatat ctgtgaaatg ctggcatttg cacctacctc 1861acagagtgca ttgtgagggt taatgaaata atgtacatct ggccttgaaa ccacctttta 1921ttacatgggg tctagaactt gacccccttg agggtgcttg ttccctctcc ctgttggtcg 1981gtgggttggt agtttctaca gttgggcagc tggttaggta gagggagttg tcaagtctct 2041gctggcccag ccaaaccctg tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa 2101tctcacccca tcccacaccc tggaggattt catctcttgt atatgatgat ctggatccac 2161caagacttgt tttatgctca gggtcaattt cttttttctt tttttttttt ttttttcttt 2221ttctttgaga ctgggtctcg ctttgttgcc caggctggag tggagtggcg tgatcttggc 2281ttactgcagc ctttgcctcc ccggctcgag cagtcctgcc tcagcctccg gagtagctgg 2341gaccacaggt tcatgccacc atggccagcc aacttttgca tgttttgtag agatggggtc 2401tcacagtgtt gcccaggctg gtctcaaact cctgggctca ggcgatccac ctgtctcagc 2461ctcccagagt gctgggatta caattgtgag ccaccacgtc cagctggaag ggtcaacatc 2521ttttacattc tgcaagcaca tctgcatttt caccccaccc ttcccctcct tctccctttt 2581tatatcccat ttttatatcg atctcttatt ttacaataaa actttgctgc cacctgtgtg 2641tctgaggggt gSEQ ID NO: 20 Human TP53 isoform i Amino Acid Sequence (NP_001263625.1)1 mddlmlspdd ieqwftedpg pdeaprmpea appvapapaa ptpaapapap swplsssvps 61qktyqgsygf rlgflhsgta ksvtctyspa lnkmfcqlak tcpvqlwvds tpppgtrvra 121maiykqsqhm tevvrrcphh ercsdsdgla ppqhlirveg nlrveylddr ntfrhsvvvp 181yeppevgsdc ttihynymcn sscmggmnrr piltiitled ssgnllgrns fevrvcacpg 241rdrrteeenl rkkgephhel ppgstkralp nntssspqpk kkpldgeyft lqdqtsfqke 301 ncSEQ ID NO: 21 Human TP53 transcript variant 3 cDNA sequence(NM_001276696.1; CDS: 320-1228) 1gatgggattg gggttttccc ctcccatgtg ctcaagactg gcgctaaaag ttttgagctt 61ctcaaaagtc tagagccacc gtccagggag caggtagctg ctgggctccg gggacacttt 121gcgttcgggc tgggagcgtg ctttccacga cggtgacacg cttccctgga ttggcagcca 181gactgccttc cgggtcactg ccatggagga gccgcagtca gatcctagcg tcgagccccc 241tctgagtcag gaaacatttt cagacctatg gaaactactt cctgaaaaca acgttctgtc 301ccccttgccg tcccaagcaa tggatgattt gatgctgtcc ccggacgata ttgaacaatg 361gttcactgaa gacccaggtc cagatgaagc tcccagaatg ccagaggctg ctccccccgt 421ggcccctgca ccagcagctc ctacaccggc ggcccctgca ccagccccct cctggcccct 481gtcatcttct gtcccttccc agaaaaccta ccagggcagc tacggtttcc gtctgggctt 541cttgcattct gggacagcca agtctgtgac ttgcacgtac tcccctgccc tcaacaagat 601gttttgccaa ctggccaaga cctgccctgt gcagctgtgg gttgattcca cacccccgcc 661cggcacccgc gtccgcgcca tggccatcta caagcagtca cagcacatga cggaggttgt 721gaggcgctgc ccccaccatg agcgctgctc agatagcgat ggtctggccc ctcctcagca 781tcttatccga gtggaaggaa atttgcgtgt ggagtatttg gatgacagaa acacttttcg 841acatagtgtg gtggtgccct atgagccgcc tgaggttggc tctgactgta ccaccatcca 901ctacaactac atgtgtaaca gttcctgcat gggcggcatg aaccggaggc ccatcctcac 961catcatcaca ctggaagact ccagtggtaa tctactggga cggaacagct ttgaggtgcg 1021tgtttgtgcc tgtcctggga gagaccggcg cacagaggaa gagaatctcc gcaagaaagg 1081ggagcctcac cacgagctgc ccccagggag cactaagcga gcactgccca acaacaccag 1141ctcctctccc cagccaaaga agaaaccact ggatggagaa tatttcaccc ttcaggacca 1201gaccagcttt caaaaagaaa attgttaaag agagcatgaa aatggttcta tgactttgcc 1261tgatacagat gctacttgac ttacgatggt gttacttcct gataaactcg tcgtaagttg 1321aaaatattat ccgtgggcgt gagcgcttcg agatgttccg agagctgaat gaggccttgg 1381aactcaagga tgcccaggct gggaaggagc caggggggag cagggctcac tccagccacc 1441tgaagtccaa aaagggtcag tctacctccc gccataaaaa actcatgttc aagacagaag 1501ggcctgactc agactgacat tctccacttc ttgttcccca ctgacagcct cccaccccca 1561tctctccctc ccctgccatt ttgggttttg ggtctttgaa cccttgcttg caataggtgt 1621gcgtcagaag cacccaggac ttccatttgc tttgtcccgg ggctccactg aacaagttgg 1681cctgcactgg tgttttgttg tggggaggag gatggggagt aggacatacc agcttagatt 1741ttaaggtttt tactgtgagg gatgtttggg agatgtaaga aatgttcttg cagttaaggg 1801ttagtttaca atcagccaca ttctaggtag gggcccactt caccgtacta accagggaag 1861ctgtccctca ctgttgaatt ttctctaact tcaaggccca tatctgtgaa atgctggcat 1921ttgcacctac ctcacagagt gcattgtgag ggttaatgaa ataatgtaca tctggccttg 1981aaaccacctt ttattacatg gggtctagaa cttgaccccc ttgagggtgc ttgttccctc 2041tccctgttgg tcggtgggtt ggtagtttct acagttgggc agctggttag gtagagggag 2101ttgtcaagtc tctgctggcc cagccaaacc ctgtctgaca acctcttggt gaaccttagt 2161acctaaaagg aaatctcacc ccatcccaca ccctggagga tttcatctct tgtatatgat 2221gatctggatc caccaagact tgttttatgc tcagggtcaa tttctttttt cttttttttt 2281tttttttttc tttttctttg agactgggtc tcgctttgtt gcccaggctg gagtggagtg 2341gcgtgatctt ggcttactgc agcctttgcc tccccggctc gagcagtcct gcctcagcct 2401ccggagtagc tgggaccaca ggttcatgcc accatggcca gccaactttt gcatgttttg 2461tagagatggg gtctcacagt gttgcccagg ctggtctcaa actcctgggc tcaggcgatc 2521cacctgtctc agcctcccag agtgctggga ttacaattgt gagccaccac gtccagctgg 2581aagggtcaac atcttttaca ttctgcaagc acatctgcat tttcacccca cccttcccct 2641ccttctccct ttttatatcc catttttata tcgatctctt attttacaat aaaactttgc 2701tgccacctgt gtgtctgagg ggtgSEQ ID NO: 22 Human TP53 isoform i Amino Acid Sequence (NP_001263626.1)1 maiykqsqhm tevvrrcphh ercsdsdgla ppqhlirveg nlrveylddr ntfrhsvvvp 61yeppevgsdc ttihynymcn sscmggmnrr piltiitled ssgnllgrns fevrvcacpg 121rdrrteeenl rkkgephhel ppgstkralp nntssspqpk kkpldgeyft lqirgrerfe 181mfrelneale lkdaqagkep ggsrahsshl kskkgqstsr hkklmfkteg pdsdSEQ ID NO: 23 Human TP53 transcript variant 5 cDNA sequence(NM_001276697.1; CDS: 360-1064) 1tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag 61tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag 121acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct 181ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct 241ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga 301cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca 361tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg 421agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa 481atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct 541atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca 601gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact 661ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga 721gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc 781ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga 841agaaaccact ggatggagaa tatttcaccc ttcagatccg tgggcgtgag cgcttcgaga 901tgttccgaga gctgaatgag gccttggaac tcaaggatgc ccaggctggg aaggagccag 961gggggagcag ggctcactcc agccacctga agtccaaaaa gggtcagtct acctcccgcc 1021ataaaaaact catgttcaag acagaagggc ctgactcaga ctgacattct ccacttcttg 1081ttccccactg acagcctccc acccccatct ctccctcccc tgccattttg ggttttgggt 1141ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac ccaggacttc catttgcttt 1201gtcccggggc tccactgaac aagttggcct gcactggtgt tttgttgtgg ggaggaggat 1261ggggagtagg acataccagc ttagatttta aggtttttac tgtgagggat gtttgggaga 1321tgtaagaaat gttcttgcag ttaagggtta gtttacaatc agccacattc taggtagggg 1381cccacttcac cgtactaacc agggaagctg tccctcactg ttgaattttc tctaacttca 1441aggcccatat ctgtgaaatg ctggcatttg cacctacctc acagagtgca ttgtgagggt 1501taatgaaata atgtacatct ggccttgaaa ccacctttta ttacatgggg tctagaactt 1561gacccccttg agggtgcttg ttccctctcc ctgttggtcg gtgggttggt agtttctaca 1621gttgggcagc tggttaggta gagggagttg tcaagtctct gctggcccag ccaaaccctg 1681tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa tctcacccca tcccacaccc 1741tggaggattt catctcttgt atatgatgat ctggatccac caagacttgt tttatgctca 1801gggtcaattt cttttttctt tttttttttt ttttttcttt ttctttgaga ctgggtctcg 1861ctttgttgcc caggctggag tggagtggcg tgatcttggc ttactgcagc ctttgcctcc 1921ccggctcgag cagtcctgcc tcagcctccg gagtagctgg gaccacaggt tcatgccacc 1981atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctg 2041gtctcaaact cctgggctca ggcgatccac ctgtctcagc ctcccagagt gctgggatta 2101caattgtgag ccaccacgtc cagctggaag ggtcaacatc ttttacattc tgcaagcaca 2161tctgcatttt caccccaccc ttcccctcct tctccctttt tatatcccat ttttatatcg 2221atctcttatt ttacaataaa actttgctgc cacctgtgtg tctgaggggt gSEQ ID NO: 24 Human TP53 isoform k Amino Acid Sequence (NP_001263627.1)1 maiykqsqhm tevvrrcphh ercsdsdgla ppqhlirveg nlrveylddr ntfrhsvvvp 61yeppevgsdc ttihynymcn sscmggmnrr piltiitled ssgnllgrns fevrvcacpg 121rdrrteeenl rkkgephhel ppgstkralp nntssspqpk kkpldgeyft lqdqtsfqke 181 ncSEQ ID NO: 25 Human TP53 transcript variant 6 cDNA sequence(NM_001276698.1; CDS: 360-908) 1tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag 61tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag 121acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct 181ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct 241ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga 301cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca 361tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg 421agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa 481atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct 541atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca 601gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact 661ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga 721gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc 781ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga 841agaaaccact ggatggagaa tatttcaccc ttcaggacca gaccagcttt caaaaagaaa 901attgttaaag agagcatgaa aatggttcta tgactttgcc tgatacagat gctacttgac 961ttacgatggt gttacttcct gataaactcg tcgtaagttg aaaatattat ccgtgggcgt 1021gagcgcttcg agatgttccg agagctgaat gaggccttgg aactcaagga tgcccaggct 1081gggaaggagc caggggggag cagggctcac tccagccacc tgaagtccaa aaagggtcag 1141tctacctccc gccataaaaa actcatgttc aagacagaag ggcctgactc agactgacat 1201tctccacttc ttgttcccca ctgacagcct cccaccccca tctctccctc ccctgccatt 1261ttgggttttg ggtctttgaa cccttgcttg caataggtgt gcgtcagaag cacccaggac 1321ttccatttgc tttgtcccgg ggctccactg aacaagttgg cctgcactgg tgttttgttg 1381tggggaggag gatggggagt aggacatacc agcttagatt ttaaggtttt tactgtgagg 1441gatgtttggg agatgtaaga aatgttcttg cagttaaggg ttagtttaca atcagccaca 1501ttctaggtag gggcccactt caccgtacta accagggaag ctgtccctca ctgttgaatt 1561ttctctaact tcaaggccca tatctgtgaa atgctggcat ttgcacctac ctcacagagt 1621gcattgtgag ggttaatgaa ataatgtaca tctggccttg aaaccacctt ttattacatg 1681gggtctagaa cttgaccccc ttgagggtgc ttgttccctc tccctgttgg tcggtgggtt 1741ggtagtttct acagttgggc agctggttag gtagagggag ttgtcaagtc tctgctggcc 1801cagccaaacc ctgtctgaca acctcttggt gaaccttagt acctaaaagg aaatctcacc 1861ccatcccaca ccctggagga tttcatctct tgtatatgat gatctggatc caccaagact 1921tgttttatgc tcagggtcaa tttctttttt cttttttttt tttttttttc tttttctttg 1981agactgggtc tcgctttgtt gcccaggctg gagtggagtg gcgtgatctt ggcttactgc 2041agcctttgcc tccccggctc gagcagtcct gcctcagcct ccggagtagc tgggaccaca 2101ggttcatgcc accatggcca gccaactttt gcatgttttg tagagatggg gtctcacagt 2161gttgcccagg ctggtctcaa actcctgggc tcaggcgatc cacctgtctc agcctcccag 2221agtgctggga ttacaattgt gagccaccac gtccagctgg aagggtcaac atcttttaca 2281ttctgcaagc acatctgcat tttcacccca cccttcccct ccttctccct ttttatatcc 2341catttttata tcgatctctt attttacaat aaaactttgc tgccacctgt gtgtctgagg 2401ggtgSEQ ID NO: 26 Human TP53 isoform 1 Amino Acid Sequence (NP_001263628.1)1 maiykqsqhm tevvrrcphh ercsdsdgla ppqhlirveg nlrveylddr ntfrhsvvvp 61yeppevgsdc ttihynymcn sscmggmnrr piltiitled ssgnllgrns fevrvcacpg 121rdrrteeenl rkkgephhel ppgstkralp nntssspqpk kkpldgeyft lqmlldlrwc 181yflinss SEQ ID NO: 27 Human TP53 transcript variant 7 cDNA sequence(NM_001276699.1; CDS: 360-923) 1tgaggccagg agatggaggc tgcagtgagc tgtgatcaca ccactgtgct ccagcctgag 61tgacagagca agaccctatc tcaaaaaaaa aaaaaaaaaa gaaaagctcc tgaggtgtag 121acgccaactc tctctagctc gctagtgggt tgcaggaggt gcttacgcat gtttgtttct 181ttgctgccgt cttccagttg ctttatctgt tcacttgtgc cctgactttc aactctgtct 241ccttcctctt cctacagtac tcccctgccc tcaacaagat gttttgccaa ctggccaaga 301cctgccctgt gcagctgtgg gttgattcca cacccccgcc cggcacccgc gtccgcgcca 361tggccatcta caagcagtca cagcacatga cggaggttgt gaggcgctgc ccccaccatg 421agcgctgctc agatagcgat ggtctggccc ctcctcagca tcttatccga gtggaaggaa 481atttgcgtgt ggagtatttg gatgacagaa acacttttcg acatagtgtg gtggtgccct 541atgagccgcc tgaggttggc tctgactgta ccaccatcca ctacaactac atgtgtaaca 601gttcctgcat gggcggcatg aaccggaggc ccatcctcac catcatcaca ctggaagact 661ccagtggtaa tctactggga cggaacagct ttgaggtgcg tgtttgtgcc tgtcctggga 721gagaccggcg cacagaggaa gagaatctcc gcaagaaagg ggagcctcac cacgagctgc 781ccccagggag cactaagcga gcactgccca acaacaccag ctcctctccc cagccaaaga 841agaaaccact ggatggagaa tatttcaccc ttcagatgct acttgactta cgatggtgtt 901acttcctgat aaactcgtcg taagttgaaa atattatccg tgggcgtgag cgcttcgaga 961tgttccgaga gctgaatgag gccttggaac tcaaggatgc ccaggctggg aaggagccag 1021gggggagcag ggctcactcc agccacctga agtccaaaaa gggtcagtct acctcccgcc 1081ataaaaaact catgttcaag acagaagggc ctgactcaga ctgacattct ccacttcttg 1141ttccccactg acagcctccc acccccatct ctccctcccc tgccattttg ggttttgggt 1201ctttgaaccc ttgcttgcaa taggtgtgcg tcagaagcac ccaggacttc catttgcttt 1261gtcccggggc tccactgaac aagttggcct gcactggtgt tttgttgtgg ggaggaggat 1321ggggagtagg acataccagc ttagatttta aggtttttac tgtgagggat gtttgggaga 1381tgtaagaaat gttcttgcag ttaagggtta gtttacaatc agccacattc taggtagggg 1441cccacttcac cgtactaacc agggaagctg tccctcactg ttgaattttc tctaacttca 1501aggcccatat ctgtgaaatg ctggcatttg cacctacctc acagagtgca ttgtgagggt 1561taatgaaata atgtacatct ggccttgaaa ccacctttta ttacatgggg tctagaactt 1621gacccccttg agggtgcttg ttccctctcc ctgttggtcg gtgggttggt agtttctaca 1681gttgggcagc tggttaggta gagggagttg tcaagtctct gctggcccag ccaaaccctg 1741tctgacaacc tcttggtgaa ccttagtacc taaaaggaaa tctcacccca tcccacaccc 1801tggaggattt catctcttgt atatgatgat ctggatccac caagacttgt tttatgctca 1861gggtcaattt cttttttctt tttttttttt ttttttcttt ttctttgaga ctgggtctcg 1921ctttgttgcc caggctggag tggagtggcg tgatcttggc ttactgcagc ctttgcctcc 1981ccggctcgag cagtcctgcc tcagcctccg gagtagctgg gaccacaggt tcatgccacc 2041atggccagcc aacttttgca tgttttgtag agatggggtc tcacagtgtt gcccaggctg 2101gtctcaaact cctgggctca ggcgatccac ctgtctcagc ctcccagagt gctgggatta 2161caattgtgag ccaccacgtc cagctggaag ggtcaacatc ttttacattc tgcaagcaca 2221tctgcatttt caccccaccc ttcccctcct tctccctttt tatatcccat ttttatatcg 2281atctcttatt ttacaataaa actttgctgc cacctgtgtg tctgaggggt gSEQ ID NO: 28 Mouse TP53 isoform b Amino Acid Sequence (NP_001120705.1)1 mtameesqsd islelplsqe tfsglwkllp pedilpsphc mddlllpqdv eeffegpsea 61lrvsgapaaq dpvtetpgpv apapatpwpl ssfvpsqkty qgnygfhlgf lqsgtaksvm 121ctyspplnkl fcqlaktcpv qlwvsatppa gsrvramaiy kksqhmtevv rrcphhercs 181dgdglappqh lirvegnlyp eyledrqtfr hsvvvpyepp eagseyttih ykymcnsscm 241ggmnrrpilt iitledssgn llgrdsfevr vcacpgrdrr teeenfrkke vlcpelppgs 301akralptcts asppqkkkpl dgeyftlkir grkrfemfre inealelkda hateesgdsr 361ahsslqpraf qalikeespn cSEQ ID NO: 29 Mouse TP53 transcript variant 2 cDNA sequence(NM_001127233.1; CDS: 158-1303) 1tttcccctcc cacgtgctca ccctggctaa agttctgtag cttcagttca ttgggaccat 61cctggctgta ggtagcgact acagttaggg ggcacctagc attcaggccc tcatcctcct 121ccttcccagc agggtgtcac gcttctccga agactggatg actgccatgg aggagtcaca 181gtcggatatc agcctcgagc tccctctgag ccaggagaca ttttcaggct tatggaaact 241acttcctcca gaagatatcc tgccatcacc tcactgcatg gacgatctgt tgctgcccca 301ggatgttgag gagttttttg aaggcccaag tgaagccctc cgagtgtcag gagctcctgc 361agcacaggac cctgtcaccg agacccctgg gccagtggcc cctgccccag ccactccatg 421gcccctgtca tcttttgtcc cttctcaaaa aacttaccag ggcaactatg gcttccacct 481gggcttcctg cagtctggga cagccaagtc tgttatgtgc acgtactctc ctcccctcaa 541taagctattc tgccagctgg cgaagacgtg ccctgtgcag ttgtgggtca gcgccacacc 601tccagctggg agccgtgtcc gcgccatggc catctacaag aagtcacagc acatgacgga 661ggtcgtgaga cgctgccccc accatgagcg ctgctccgat ggtgatggcc tggctcctcc 721ccagcatctt atccgggtgg aaggaaattt gtatcccgag tatctggaag acaggcagac 781ttttcgccac agcgtggtgg taccttatga gccacccgag gccggctctg agtataccac 841catccactac aagtacatgt gtaatagctc ctgcatgggg ggcatgaacc gccgacctat 901ccttaccatc atcacactgg aagactccag tgggaacctt ctgggacggg acagctttga 961ggttcgtgtt tgtgcctgcc ctgggagaga ccgccgtaca gaagaagaaa atttccgcaa 1021aaaggaagtc ctttgccctg aactgccccc agggagcgca aagagagcgc tgcccacctg 1081cacaagcgcc tctcccccgc aaaagaaaaa accacttgat ggagagtatt tcaccctcaa 1141gatccgcggg cgtaaacgct tcgagatgtt ccgggagctg aatgaggcct tagagttaaa 1201ggatgcccat gctacagagg agtctggaga cagcagggct cactccagcc tccagcctag 1261agccttccaa gccttgatca aggaggaaag cccaaactgc tagctcccat cacttcatcc 1321ctcccctttt ctgtcttcct atagctacct gaagaccaag aagggccagt ctacttcccg 1381ccataaaaaa acaatggtca agaaagtggg gcctgactca gactgactgc ctctgcatcc 1441cgtccccatc accagcctcc ccctctcctt gctgtcttat gacttcaggg ctgagacaca 1501atcctcccgg tcccttctgc tgcctttttt accttgtagc tagggctcag ccccctctct 1561gagtagtggt tcctggccca agttggggaa taggttgata gttgtcaggt ctctgctggc 1621ccagcgaaat tctatccagc cagttgttgg accctggcac ctacaatgaa atctcaccct 1681accccacacc ctgtaagatt ctatcttggg ccctcatagg gtccatatcc tccagggcct 1741actttccttc cattctgcaa agcctgtctg catttatcca ccccccaccc tgtctccctc 1801tttttttttt ttttacccct ttttatatat caatttccta ttttacaata aaattttgtt 1861atcacttaaa aaaaaaaSEQ ID NO: 30 Mouse TP53 isoform a Amino Acid Sequence (NP_035770.2) 1mtameesqsd islelplsqe tfsglwkllp pedilpsphc mddlllpqdv eeffegpsea 61lrvsgapaaq dpvtetpgpv apapatpwpl ssfvpsqkty qgnygfhlgf lqsgtaksvm 121ctyspplnkl fcqlaktcpv qlwvsatppa gsrvramaiy kksqhmtevv rrcphhercs 181dgdglappqh lirvegnlyp eyledrqtfr hsvvvpyepp eagseyttih ykymcnsscm 241ggmnrrpilt iitledssgn llgrdsfevr vcacpgrdrr teeenfrkke vlcpelppgs 301akralptcts asppqkkkpl dgeyftlkir grkrfemfre lnealelkda hateesgdsr 361ahssylktkk gqstsrhkkt mvkkvgpdsdSEQ ID NO: 31 Mouse TP53 transcript variant 1 cDNA sequence (NM_011640.3;CDS: 158-1330) 1tttcccctcc cacgtgctca ccctggctaa agttctgtag cttcagttca ttgggaccat 61cctggctgta ggtagcgact acagttaggg ggcacctagc attcaggccc tcatcctcct 121ccttcccagc agggtgtcac gcttctccga agactggatg actgccatgg aggagtcaca 181gtcggatatc agcctcgagc tccctctgag ccaggagaca ttttcaggct tatggaaact 241acttcctcca gaagatatcc tgccatcacc tcactgcatg gacgatctgt tgctgcccca 301ggatgttgag gagttttttg aaggcccaag tgaagccctc cgagtgtcag gagctcctgc 361agcacaggac cctgtcaccg agacccctgg gccagtggcc cctgccccag ccactccatg 421gcccctgtca tcttttgtcc cttctcaaaa aacttaccag ggcaactatg gcttccacct 481gggcttcctg cagtctggga cagccaagtc tgttatgtgc acgtactctc ctcccctcaa 541taagctattc tgccagctgg cgaagacgtg ccctgtgcag ttgtgggtca gcgccacacc 601tccagctggg agccgtgtcc gcgccatggc catctacaag aagtcacagc acatgacgga 661ggtcgtgaga cgctgccccc accatgagcg ctgctccgat ggtgatggcc tggctcctcc 721ccagcatctt atccgggtgg aaggaaattt gtatcccgag tatctggaag acaggcagac 781ttttcgccac agcgtggtgg taccttatga gccacccgag gccggctctg agtataccac 841catccactac aagtacatgt gtaatagctc ctgcatgggg ggcatgaacc gccgacctat 901ccttaccatc atcacactgg aagactccag tgggaacctt ctgggacggg acagctttga 961ggttcgtgtt tgtgcctgcc ctgggagaga ccgccgtaca gaagaagaaa atttccgcaa 1021aaaggaagtc ctttgccctg aactgccccc agggagcgca aagagagcgc tgcccacctg 1081cacaagcgcc tctcccccgc aaaagaaaaa accacttgat ggagagtatt tcaccctcaa 1141gatccgcggg cgtaaacgct tcgagatgtt ccgggagctg aatgaggcct tagagttaaa 1201ggatgcccat gctacagagg agtctggaga cagcagggct cactccagct acctgaagac 1261caagaagggc cagtctactt cccgccataa aaaaacaatg gtcaagaaag tggggcctga 1321ctcagactga ctgcctctgc atcccgtccc catcaccagc ctccccctct ccttgctgtc 1381ttatgacttc agggctgaga cacaatcctc ccggtccctt ctgctgcctt ttttaccttg 1441tagctagggc tcagccccct ctctgagtag tggttcctgg cccaagttgg ggaataggtt 1501gatagttgtc aggtctctgc tggcccagcg aaattctatc cagccagttg ttggaccctg 1561gcacctacaa tgaaatctca ccctacccca caccctgtaa gattctatct tgggccctca 1621tagggtccat atcctccagg gcctactttc cttccattct gcaaagcctg tctgcattta 1681tccacccccc accctgtctc cctctttttt ttttttttac ccctttttat atatcaattt 1741cctattttac aataaaattt tgttatcact taaaaaaaaa aSEQ ID NO: 32 Human RB1 Amino Acid Sequence (NP_000312.2) 1mppktprkta ataaaaaaep papppppppe edpeqdsgpe dlplvrlefe eteepdftal 61cqklkipdhv rerawltwek vssvdgvlgg yiqkkkelwg icifiaavdl demsftftel 121qknieisvhk ffnllkeidt stkvdnamsr llkkydvlfa lfsklertce liyltqpsss 181isteinsalv lkvswitfll akgevlqmed dlvisfqlml cvldyfikls ppmllkepyk 241tavipingsp rtprrgqnrs ariakqlend triievlcke hecnidevkn vyfknfipfm 301nslglvtsng lpevenlskr yeeiylknkd ldarlfldhd ktlqtdsids fetqrtprks 361nldeevnvip phtpvrtvmn tiqqlmmiln sasdqpsenl isyfnnctvn pkesilkrvk 421digyifkekf akavgqgcve igsqryklgv rlyyrvmesm lkseeerlsi qnfskllndn 481ifhmsllaca levvmatysr stsqnldsgt dlsfpwilnv lnlkafdfyk viesfikaeg 541nltremikhl ercehrimes lawlsdsplf dlikqskdre gptdhlesac plnlplqnnh 601taadmylspv rspkkkgstt rvnstanaet qatsafqtqk plkstslslf ykkvyrlayl 661rlntlcerll sehpelehii wtlfqhtlqn eyelmrdrhl dqimmcsmyg ickvknidlk 721fkiivtaykd lphavqetfk rvlikeeeyd siivfynsvf mqrlktnilq yastrpptls 781piphiprspy kfpssplrip ggniyisplk spykiseglp tptkmtprsr ilvsigesfg 841tsekfqkinq mvcnsdrvlk rsaegsnppk plkklrfdie gsdeadgskh lpgeskfqqk 901laemtstrtr mqkqkmndsm dtsnkeekSEQ ID NO: 33 Human RB1 transcript DNA sequence (NM_000321.2;CDS: 167 . . . 2953) 1gctcagttgc cgggcggggg agggcgcgtc cggtttttct caggggacgt tgaaattatt 61tttgtaacgg gagtcgggag aggacggggc gtgccccgac gtgcgcgcgc gtcgtcctcc 121ccggcgctcc tccacagctc gctggctccc gccgcggaaa ggcgtcatgc cgcccaaaac 181cccccgaaaa acggccgcca ccgccgccgc tgccgccgcg gaacccccgg caccgccgcc 241gccgccccct cctgaggagg acccagagca ggacagcggc ccggaggacc tgcctctcgt 301caggcttgag tttgaagaaa cagaagaacc tgattttact gcattatgtc agaaattaaa 361gataccagat catgtcagag agagagcttg gttaacttgg gagaaagttt catctgtgga 421tggagtattg ggaggttata ttcaaaagaa aaaggaactg tggggaatct gtatctttat 481tgcagcagtt gacctagatg agatgtcgtt cacttttact gagctacaga aaaacataga 541aatcagtgtc cataaattct ttaacttact aaaagaaatt gataccagta ccaaagttga 601taatgctatg tcaagactgt tgaagaagta tgatgtattg tttgcactct tcagcaaatt 661ggaaaggaca tgtgaactta tatatttgac acaacccagc agttcgatat ctactgaaat 721aaattctgca ttggtgctaa aagtttcttg gatcacattt ttattagcta aaggggaagt 781attacaaatg gaagatgatc tggtgatttc atttcagtta atgctatgtg tccttgacta 841ttttattaaa ctctcacctc ccatgttgct caaagaacca tataaaacag ctgttatacc 901cattaatggt tcacctcgaa cacccaggcg aggtcagaac aggagtgcac ggatagcaaa 961acaactagaa aatgatacaa gaattattga agttctctgt aaagaacatg aatgtaatat 1021agatgaggtg aaaaatgttt atttcaaaaa ttttatacct tttatgaatt ctcttggact 1081tgtaacatct aatggacttc cagaggttga aaatctttct aaacgatacg aagaaattta 1141tcttaaaaat aaagatctag atgcaagatt atttttggat catgataaaa ctcttcagac 1201tgattctata gacagttttg aaacacagag aacaccacga aaaagtaacc ttgatgaaga 1261ggtgaatgta attcctccac acactccagt taggactgtt atgaacacta tccaacaatt 1321aatgatgatt ttaaattcag caagtgatca accttcagaa aatctgattt cctattttaa 1381caactgcaca gtgaatccaa aagaaagtat actgaaaaga gtgaaggata taggatacat 1441ctttaaagag aaatttgcta aagctgtggg acagggttgt gtcgaaattg gatcacagcg 1501atacaaactt ggagttcgct tgtattaccg agtaatggaa tccatgctta aatcagaaga 1561agaacgatta tccattcaaa attttagcaa acttctgaat gacaacattt ttcatatgtc 1621tttattggcg tgcgctcttg aggttgtaat ggccacatat agcagaagta catctcagaa 1681tcttgattct ggaacagatt tgtctttccc atggattctg aatgtgctta atttaaaagc 1741ctttgatttt tacaaagtga tcgaaagttt tatcaaagca gaaggcaact tgacaagaga 1801aatgataaaa catttagaac gatgtgaaca tcgaatcatg gaatcccttg catggctctc 1861agattcacct ttatttgatc ttattaaaca atcaaaggac cgagaaggac caactgatca 1921ccttgaatct gcttgtcctc ttaatcttcc tctccagaat aatcacactg cagcagatat 1981gtatctttct cctgtaagat ctccaaagaa aaaaggttca actacgcgtg taaattctac 2041tgcaaatgca gagacacaag caacctcagc cttccagacc cagaagccat tgaaatctac 2101ctctctttca ctgttttata aaaaagtgta tcggctagcc tatctccggc taaatacact 2161ttgtgaacgc cttctgtctg agcacccaga attagaacat atcatctgga cccttttcca 2221gcacaccctg cagaatgagt atgaactcat gagagacagg catttggacc aaattatgat 2281gtgttccatg tatggcatat gcaaagtgaa gaatatagac cttaaattca aaatcattgt 2341aacagcatac aaggatcttc ctcatgctgt tcaggagaca ttcaaacgtg ttttgatcaa 2401agaagaggag tatgattcta ttatagtatt ctataactcg gtcttcatgc agagactgaa 2461aacaaatatt ttgcagtatg cttccaccag gccccctacc ttgtcaccaa tacctcacat 2521tcctcgaagc ccttacaagt ttcctagttc acccttacgg attcctggag ggaacatcta 2581tatttcaccc ctgaagagtc catataaaat ttcagaaggt ctgccaacac caacaaaaat 2641gactccaaga tcaagaatct tagtatcaat tggtgaatca ttcgggactt ctgagaagtt 2701ccagaaaata aatcagatgg tatgtaacag cgaccgtgtg ctcaaaagaa gtgctgaagg 2761aagcaaccct cctaaaccac tgaaaaaact acgctttgat attgaaggat cagatgaagc 2821agatggaagt aaacatctcc caggagagtc caaatttcag cagaaactgg cagaaatgac 2881ttctactcga acacgaatgc aaaagcagaa aatgaatgat agcatggata cctcaaacaa 2941ggaagagaaa tgaggatctc aggaccttgg tggacactgt gtacacctct ggattcattg 3001tctctcacag atgtgactgt ataactttcc caggttctgt ttatggccac atttaatatc 3061ttcagctctt tttgtggata taaaatgtgc agatgcaatt gtttgggtga ttcctaagcc 3121acttgaaatg ttagtcattg ttatttatac aagattgaaa atcttgtgta aatcctgcca 3181tttaaaaagt tgtagcagat tgtttcctct tccaaagtaa aattgctgtg ctttatggat 3241agtaagaatg gccctagagt gggagtcctg ataacccagg cctgtctgac tactttgcct 3301tcttttgtag catataggtg atgtttgctc ttgtttttat taatttatat gtatattttt 3361ttaatttaac atgaacaccc ttagaaaatg tgtcctatct atcttccaaa tgcaatttga 3421ttgactgccc attcaccaaa attatcctga actcttctgc aaaaatggat attattagaa 3481attagaaaaa aattactaat tttacacatt agattttatt ttactattgg aatctgatat 3541actgtgtgct tgttttataa aattttgctt ttaattaaat aaaagctgga agcaaagtat 3601aaccatatga tactatcata ctactgaaac agatttcata cctcagaatg taaaagaact 3661tactgattat tttcttcatc caacttatgt ttttaaatga ggattattga tagtactctt 3721ggtttttata ccattcagat cactgaattt ataaagtacc catctagtac ttgaaaaagt 3781aaagtgttct gccagatctt aggtatagag gaccctaaca cagtatatcc caagtgcact 3841ttctaatgtt tctgggtcct gaagaattaa gatacaaatt aattttactc cataaacaga 3901ctgttaatta taggagcctt aatttttttt tcatagagat ttgtctaatt gcatctcaaa 3961attattctgc cctccttaat ttgggaaggt ttgtgttttc tctggaatgg tacatgtctt 4021ccatgtatct tttgaactgg caattgtcta tttatctttt atttttttaa gtcagtatgg 4081tctaacactg gcatgttcaa agccacatta tttctagtcc aaaattacaa gtaatcaagg 4141gtcattatgg gttaggcatt aatgtttcta tctgattttg tgcaaaagct tcaaattaaa 4201acagctgcat tagaaaaaga ggcgcttctc ccctccccta cacctaaagg tgtatttaaa 4261ctatcttgtg tgattaactt atttagagat gctgtaactt aaaatagggg atatttaagg 4321tagcttcagc tagcttttag gaaaatcact ttgtctaact cagaattatt tttaaaaaga 4381aatctggtct tgttagaaaa caaaatttta ttttgtgctc atttaagttt caaacttact 4441attttgacag ttattttgat aacaatgaca ctagaaaact tgactccatt tcatcattgt 4501ttctgcatga atatcataca aatcagttag tttttaggtc aagggcttac tatttctggg 4561tcttttgcta ctaagttcac attagaatta gtgccagaat tttaggaact tcagagatcg 4621tgtattgaga tttcttaaat aatgcttcag atattattgc tttattgctt ttttgtattg 4681gttaaaactg tacatttaaa attgctatgt tactattttc tacaattaat agtttgtcta 4741ttttaaaata aattagttgt taagagtctt aaSEQ ID NO: 34 Mouse RB1 Amino Acid Sequence ( ) 1mppkaprraa aaeppppppp ppreddpaqd sgpeelplar lefeeieepe fialcqklkv 61pdhvrerawl twekvssvdg ilegyiqkkk elwgicifia avdldempft ftelqksiet 121svykffdllk eidtstkvdn amsrllkkyn vlcalyskle rtceliyltq pssalstein 181smlvlkiswi tfllakgevl qmeddlvisf qlmlcvvdyf ikfsppallr epyktaaipi 241ngsprtprrg qnrsariakq lendtriiev lckehecnid evknvyfknf ipfinslgiv 301ssnglpeves lskryeevyl knkdldarlf ldhdktlqtd pidsfetert prknnpdeea 361nvvtphtpvr tvmntiqqlm vilnsasdqp senlisyfnn ctvnpkenil krvkdvghif 421kekfanavgq gcvdigvqry klgvrlyyrv mesmlkseee rlsiqnfskl lndnifhmsl 481lacalevvma tysrstlqhl dsgtdlsfpw ilnvlnlkaf dfykviesfi kveanltrem 541ikhlercehr imeslawlsd splfdlikqs kdgegpdnle pacplslplq gnhtaadmyl 601splrspkkrt sttrvnsaan tetqaasafh tqkplkstsl alfykkvyrl aylrlntlca 661rllsdhpele hiiwtlfqht lqneyelmrd rhldqimmcs mygickvkni dlkfkiivta 721ykdlphaaqe tfkrvliree efdsiivfyn svfmqrlktn ilqyastrpp tlspiphipr 781spykfssspl ripggniyis plkspykise glptptkmtp rsrilvsige sfgtsekfqk 841inqmvcnsdr vlkrsaeggn ppkplkklrf diegadeadg skhlpaeskf qqklaemtst 901rtrmqkqrmn eskdvsnkee kSEQ ID NO: 35 Mouse RB1 transcript DNA sequence (NM_009029.3; CDS:182 . . . 2947) 1gttttcccgc ggttggcccg ggcgctcggt tgccgggcgc gtccggtttt cctcggggga 61cgttcccatt atttttgtaa cgggagtcgg gtgaggacgg ggcgtgcccg gcgtgcgcgc 121gcgcccgccc gcctccccgc gcgcctccct cggctgctcg cgccggcccg cgctgcgcgt 181catgccgccc aaagccccgc gcagagccgc ggccgccgag cccccgccac cgccgccgcc 241gccgcctcgg gaggacgacc ccgcgcagga cagcggcccc gaagagctgc ccctggccag 301gcttgagttt gaagaaattg aagaacccga atttattgca ttatgtcaaa agttaaaggt 361acccgatcat gtcagagaaa gagcttggct aacttgggag aaagtttcat ccgtggatgg 421aatcctggaa ggatatattc aaaagaagaa ggaactctgg ggcatctgca tctttatcgc 481agcagttgat ctagatgaga tgccattcac ttttactgag ctacagaaaa gcatagaaac 541cagtgtctat aaattctttg acttattaaa agaaatcgat accagtacca aggttgataa 601tgctatgtca agactattga agaagtataa tgtgttatgt gcactctaca gcaaattaga 661acggacgtgt gaacttatat atttgacaca acccagcagt gcgttatcta ctgaaataaa 721ttctatgttg gtgctaaaaa tttcttggat cactttttta ctagctaaag gagaagtatt 781acagatggaa gatgacctgg taatctcatt tcagctaatg ttgtgtgtag ttgactattt 841tattaagttc tcacctcctg cactactcag agagccatac aaaacagctg caatccccat 901taatggttca cctcgaacac ccagaagagg tcagaacagg agcgctcgga tagcaaaaca 961actagaaaat gatacgagga ttatcgaggt tctctgtaaa gaacacgagt gtaatataga 1021tgaggtgaaa aatgtttatt tcaaaaattt tatccctttt ataaattcac ttggaattgt 1081atcatctaat ggacttccag aggttgaaag tctttctaaa cgctatgaag aagtttatct 1141taaaaacaaa gatttagatg caagactgtt tttggatcat gataaaacac ttcagactga 1201tcctatagac agttttgaaa cagagagaac gccacgaaaa aacaaccctg atgaagaggc 1261aaacgtggtt actccacaca ctccagttag gactgttatg aatactattc aacaattaat 1321ggtgatttta aattctgcaa gtgatcagcc atcagaaaat ctgatttcct acttcaataa 1381ttgcacagtg aatccaaaag aaaatatcct aaagagagta aaggatgttg ggcacatctt 1441taaagagaag tttgctaacg ctgtgggcca gggctgtgtt gacatcggag tacagcgata 1501taaacttgga gtccgattgt attaccgtgt gatggaatcc atgcttaaat cagaagaaga 1561acgtttgtcc attcagaatt ttagcaaact cctaaatgac aacatctttc atatgtcttt 1621actggcctgt gctcttgaag ttgtaatggc tacgtatagc agaagtacat tgcagcatct 1681tgattctgga acagatttgt ccttcccgtg gattctgaac gtacttaatt taaaagcctt 1741tgatttttac aaagtgattg aaagttttat caaagtggaa gccaacttga caagagaaat 1801gataaaacat ttagaaagat gtgagcatcg aatcatggaa tcccttgcat ggctttcaga 1861ttcaccttta tttgatctca ttaagcagtc caaggatgga gaaggacctg ataaccttga 1921acctgcttgt cctctcagcc tgcctctcca gggtaaccat actgcagcag atatgtatct 1981ttctcctcta agatctccaa agaaaagaac ttccactaca cgtgtaaatt ctgctgcaaa 2041tacagagaca caagcagcct cagccttcca tactcagaag ccattgaaat ctacctccct 2101tgccctgttt tacaaaaaag tgtaccgtct agcatatctc cgactaaata cactctgtgc 2161acgccttctg tctgaccacc cagagctaga gcacatcatc tggactctgt ttcagcatac 2221attgcaaaat gagtatgagc tcatgagaga ccgacatttg gaccagatta tgatgtgctc 2281tatgtatggc atctgcaagg tgaagaacat cgacctcaag ttcaaaatca tcgtcactgc 2341ctacaaggat cttcctcacg ctgcccagga gacctttaaa cgtgttttga tcagagaaga 2401ggagtttgat tccattatag tattctataa ctccgttttc atgcagagac taaaaacaaa 2461tattttacag tatgcctcca ccaggcctcc taccttgtca ccaatacctc acattcctcg 2521aagcccttac aagttttcta gttcaccctt acggattcct ggaggtaaca tctatatatc 2581acccctaaag agtccttata aaatttcaga aggtctgcca acacccacaa aaatgactcc 2641gagatcaaga atcttggtct caattggtga atcatttggg acatctgaaa agttccagaa 2701aataaaccag atggtgtgta atagtgacag agtgctcaaa agaagtgctg aaggcggcaa 2761cccccccaaa ccactgaaaa agctgcgctt tgacatcgag ggagccgatg aagcagatgg 2821gagtaaacat ctcccagcgg agtccaaatt ccaacagaaa ctggcagaaa tgacttccac 2881tcgaacacga atgcaaaagc agagaatgaa tgagagcaag gatgtctcaa acaaggagga 2941aaagtgagga cctcagggcc ctggaccctc agccctgggg acaccagact cctggctcat 3001ggttgtgact agttcccagg ttctgctcat gttagagata taaaatgtgc aggtacaagc 3061tgaatatttg tgtgggtgat tcgtaagcca cttcaatgtt gtaatcaatg gtagagaatt 3121gatagcacac aggattgaga atcttgtgca gatcatgcca tttaaaatat gaaagcaagt 3181tgtttgcatt tccaacatga gcctgctgcc ctcagaagtg agggcctctg caggggtcct 3241gaccccctac atctggctga ctactttgcc tttcctcatg gcacatgtgt gatgtttgct 3301cttggtttta ttaatttata tgtatttttt aatttaacgt gaataccctt agaaaatgtg 3361tcttgtcttc caaatgcaag ttgattgact gtccacattc aaccaaatta tcttgaatct 3421tctactgaaa cagattgtta caaactggga aaaagtacta atttctacac attggactat 3481tttaatatta gaatctaatg tgccgtgtgt ttgtttcaca tattttactt ttgaaataca 3541agcaaaaaaa gtataatcat atgatactgt cttactactg acacagattt catacctcag 3601accctctaag aaccgattct tttattcacc caacacatgc tttgaactga agactattga 3661taatactccg aggttgtttt tttctttcaa tcattcagat cactgaattt ataagtaccc 3721atgtagtact tgaaagtcaa gtttggccac aactgtgctt aagaggaccc tagtacagta 3781caacccaagt gcacttttta atgtttctgg gtcctgaaga atcaagatac aaattaattg 3841tgatttacaa gcagactgtt aactatagaa gccttcagtt tttttccctc atagacgtgt 3901ctaattacat ctcaacagtt tactctgttc ttctacatct ggggatgttt gtgttctctc 3961tggaatggta catcttccag ggtcttttga acttgcagtt atctattttt taagccaatc 4021tggtctaata actctggctt cttcaaagcc acaccatttc tagtccagct gtgcagaaac 4081ttcagatgaa aacagctgca ttgaaaatag aggcactccc ttcacccccc acctaaaggt 4141gtatttaaat tatcttgtgg gattaactta tttagagatg gtataattta aaatagggga 4201tatttaaggt agcatcagct agcatttaag aaaatcactt tttctaaact ccatactttt 4261tgaaaagaaa tctggtcttg ttaggaaaca aatttctatt ttgtcctcaa tttagtttca 4321gttttactag tttgatagtt atctcaataa caaaagcaat agacagcttc ccccatttct 4381tcattaagtt ttgcatgatc atcacacaga ttagttaggt tttaggtcaa gggcttacca 4441tacttctagg tcttttgcta gtgagttcaa gttagaatta gtgacagaat cataggaatt 4501ttcagagatc ctgcttcgag atttcttaaa gctgcagaca ctgcactatt ggttttgttt 4561ttttgtaccg gttgaaacta tacattcaaa ttgctatgtt cctattttct ataatagttt 4621gtctatttta aaataaacta gttgttcaga gccttaaaaa aaaaaaaaaa aaaSEQ ID NO: 36 Human CYLD Isoform 1 Amino Acid Sequence (NP_056062.1) 1mssglwsqek vtspyweeri fylllqecsv tdkqtqkllk vpkgsigqyi qdrsvghsri 61psakgkknqi qlkileqpha vlfvdekdvv einekftell laitnceerf slfknrnrls 121kglqidvgcp vkvqlrsgee kfpgvvrfrg pllaertvsg iffgvellee grgqgftdgv 181yqgkqlfqcd edcgvfvald kleliedddt alesdyagpg dtmqvelppl einsrvslkv 241getiesgtvi fcdvlpgkes lgyfvgvdmd npignwdgrf dgvqlcsfac vestillhin 301diipalsesv tqerrppkla fmsrgvgdkg ssshnkpkat gstsdpgnrn rselfytlng 361ssvdsqpqsk skntwyidev aedpakslte istdfdrssp plqpppvnsl ttenrfhslp 421fsltkmpntn gsighsplsl saqsvmeeln tapvqesppl amppgnshgl evgslaevke 481nppfygvirw igqppglnev lagleledec agctdgtfrg tryftcalkk alfvklkscr 541pdsrfaslqp vsnqiercns lafggylsev veentppkme kegleimigk kkgiqghyns 601cyldstlfcl fafssvldtv llrpkekndv eyysetqell rteivnplri ygyvcatkim 661klrkilekve aasgftseek dpeeflnilf hhilrvepll kirsagqkvq dcyfyqifme 721knekvgvpti qqllewsfin snlkfaeaps cliiqmprfg kdfklfkkif pslelnitdl 781ledtprqcri cgglamyecr ecyddpdisa gkikqfcktc ntqvhlhpkr lnhkynpvsl 841pkdlpdwdwr hgcipcqnme lfavlciets hyvafvkygk ddsawlffds madrdggqng 901fnipqvtpcp evgeylkmsl edlhsldsrr iqgcarrllc daymcmyqsp tmslykSEQ ID NO: 37 Human CYLD transcript variant 1 cDNA sequence (NM_015247.2;CDS: 416-3286) 1gtgcggttcg gaggcggggc aggtgggggc gggcccaggt agcaggtttg gctgcgcggg 61ggccgcgcgt cggagtttcc ccctttctag ggtgaggatg gttctacaca gccacccgga 121gttccttagt tgaaaggtgc gccctgctgt gacagaatgt ggtaattgta atctttaaca 181ttttcatgta aaacatattt cctgatcatc tttccattgt cttcatggaa aattgataaa 241tatttgtgcc ttccaactct cgtcttggtt gaatgacttc atcttaatac aacatggaca 301ccacgttgct gaaaacatgc tttgggactg ccactgaatt tatcttttgc ggttttatga 361caaagttatt agtagtttcc cttttttgaa ttagtatttt gaagttaata tcacaatgag 421ttcaggctta tggagccaag aaaaagtcac ttcaccctac tgggaagagc ggatttttta 481cttgcttctt caagaatgca gcgttacaga caaacaaaca caaaagctcc ttaaagtacc 541gaagggaagt ataggacagt atattcaaga tcgttctgtg gggcattcaa ggattccttc 601tgcaaaaggc aagaaaaatc agattggatt aaaaattcta gagcaacctc atgcagttct 661ctttgttgat gaaaaggatg ttgtagagat aaatgaaaag ttcacagagt tacttttggc 721aattaccaat tgtgaggaga ggttcagcct gtttaaaaac agaaacagac taagtaaagg 781cctccaaata gacgtgggct gtcctgtgaa agtacagctg agatctgggg aagaaaaatt 841tcctggagtt gtacgcttca gaggacccct gttagcagag aggacagtct ccggaatatt 901ctttggagtt gaattgctgg aagaaggtcg tggtcaaggt ttcactgacg gggtgtacca 961agggaaacag ctttttcagt gtgatgaaga ttgtggcgtg tttgttgcat tggacaagct 1021agaactcata gaagatgatg acactgcatt ggaaagtgat tacgcaggtc ctggggacac 1081aatgcaggtc gaacttcctc ctttggaaat aaactccaga gtttctttga aggttggaga 1141aacaatagaa tctggaacag ttatattctg tgatgttttg ccaggaaaag aaagcttagg 1201atattttgtt ggtgtggaca tggataaccc tattggcaac tgggatggaa gatttgatgg 1261agtgcagctt tgtagttttg cgtgtgttga aagtacaatt ctattgcaca tcaatgatat 1321catcccagct ttatcagaga gtgtgacgca ggaaaggagg cctcccaaac ttgcctttat 1381gtcaagaggt gttggggaca aaggttcatc cagtcataat aaaccaaagg ctacaggatc 1441tacctcagac cctggaaata gaaacagatc tgaattattt tataccttaa atgggtcttc 1501tgttgactca caaccacaat ccaaatcaaa aaatacatgg tacattgatg aagttgcaga 1561agaccctgca aaatctctta cagagatatc tacagacttt gaccgttctt caccaccact 1621ccagcctcct cctgtgaact cactgaccac cgagaacaga ttccactctt taccattcag 1681tctcaccaag atgcccaata ccaatggaag tattggccac agtccacttt ctctgtcagc 1741ccagtctgta atggaagagc taaacactgc acccgtccaa gagagtccac ccttggccat 1801gcctcctggg aactcacatg gtctagaagt gggctcattg gctgaagtta aggagaaccc 1861tcctttctat ggggtaatcc gttggatcgg tcagccacca ggactgaatg aagtgctcgc 1921tggactggaa ctggaagatg agtgtgcagg ctgtacggat ggaaccttca gaggcactcg 1981gtatttcacc tgtgccctga agaaggcgct gtttgtgaaa ctgaagagct gcaggcctga 2041ctctaggttt gcatcattgc agccggtttc caatcagatt gagcgctgta actctttagc 2101atttggaggc tacttaagtg aagtagtaga agaaaatact ccaccaaaaa tggaaaaaga 2161aggcttggag ataatgattg ggaagaagaa aggcatccag ggtcattaca attcttgtta 2221cttagactca accttattct gcttatttgc ttttagttct gttctggaca ctgtgttact 2281tagacccaaa gaaaagaacg atgtagaata ttatagtgaa acccaagagc tactgaggac 2341agaaattgtt aatcctctga gaatatatgg atatgtgtgt gccacaaaaa ttatgaaact 2401gaggaaaata cttgaaaagg tggaggctgc atcaggattt acctctgaag aaaaagatcc 2461tgaggaattc ttgaatattc tgtttcatca tattttaagg gtagaacctt tgctaaaaat 2521aagatcagca ggtcaaaagg tacaagattg ttacttctat caaattttta tggaaaaaaa 2581tgagaaagtt ggcgttccca caattcagca gttgttagaa tggtctttta tcaacagtaa 2641cctgaaattt gcagaggcac catcatgtct gattattcag atgcctcgat ttggaaaaga 2701ctttaaacta tttaaaaaaa tttttccttc tctggaatta aatataacag atttacttga 2761agacactccc agacagtgcc ggatatgtgg agggcttgca atgtatgagt gtagagaatg 2821ctacgacgat ccggacatct cagctggaaa aatcaagcag ttttgtaaaa cctgcaacac 2881tcaagtccac cttcatccga agaggctgaa tcataaatat aacccagtgt cacttcccaa 2941agacttaccc gactgggact ggagacacgg ctgcatccct tgccagaata tggagttatt 3001tgctgttctc tgcatagaaa caagccacta tgttgctttt gtgaagtatg ggaaggacga 3061ttctgcctgg ctcttctttg acagcatggc cgatcgggat ggtggtcaga atggcttcaa 3121cattcctcaa gtcaccccat gcccagaagt aggagagtac ttgaagatgt ctctggaaga 3181cctgcattcc ttggactcca ggagaatcca aggctgtgca cgaagactgc tttgtgatgc 3241atatatgtgc atgtaccaga gtccaacaat gagtttgtac aaataactgg ggtcatcggg 3301aaaggcaaag aaactgaagg cagagtccta acgttgcatc ttattcgagc tggcagttct 3361gttcacgtcc attgccggca atggatgtct ttgtggtgat gatccttcag aaaaggatgc 3421ctctgtttaa aaacaaattg cttttgtgtc cctgaagtat ttaataagaa gcattttgca 3481ctctagaaag tatgtttgtg ttggtttttt aagaagtcta aatgaagtta ttaatacctg 3541aagctttaag ttaagtgcat tgatcatatg atatttttgg aagcatacaa ttttaattgt 3601ggaagtttaa agcctctttt agtccattga gaatgtaaat aaatgtgtct tctttatgga 3661ccaaggatat gaaatcattt ttcttttgta gctaacggtt gccttgagga agaaataatt 3721tggttttatt aagagtctac tctcaatcca gttattagag atgtactgag tttgatttgt 3781taatcctttc tatatactgc tgatcttgca tgtctacaat ctgctcagtt tttctgtgtt 3841tctgcaatag tggtcagaaa aatacttaaa ttcccttaat ggtgttgttt tctatttgtt 3901ctggttttga gataaatgag tgattctgtc cccaaatgtc catttttgaa gtgattttcc 3961tggaggatta gggtatttag cagttgaagc tcttcattca tagtagttac tgtcagctaa 4021caggtttttt aaggctttta actattaata ttttatggaa tggggcaaag taaattgatg 4081aaagaattgg agtgataata gtcctttaca aacatacagt ccataagaaa atgaatttgg 4141catatagaat tattacaatt tcctgggaga gatggatatt taaacctcta ttattttaga 4201caagactgtc tagaacttaa gtttgatctg tcagccagta ctcccattaa attcagtgta 4261gtttcacttg atagaatcag atatgttatc gaaatgttag cagcagcttc atcctccttc 4321tgattaaagt aagtagaaat gggatgtttt gtttaataac agccatagtg tgtgtttaga 4381ccacagcgga tgttgtagac caggaccata gatgatacat gtcagtgctg tggaatgtgc 4441attctctgag tgttgttttg tggtatcatt gtctttcctg aatgactttc taactgtgca 4501gaaaggcaga aaagtcatca tatgtatatg tcatatgact ttataaaata tttaatgtga 4561caaaaagtgg aaagaatctt tacaaaccct gcaattactt ttttaaaggc acttttactc 4621tttggtttta tcattccatt ttgctaatat ttactagctt tataaattac agtaaggtac 4681aaaaactcat cttgtaatat tttcattttt gaagtgaaaa agtacatata ttttgcacaa 4741ggttttatac tgctaagtgc ttggttgggg tggtgagatg atgattagat caggggtgag 4801gctgagagac tctgggttta gggctagccc tgcctccatc tcccttgggt aaaatgaagg 4861gtgtggggta aaagatgcat aaggcctttt ctagctctga cagcctagaa gtccaatcac 4921cctgtaataa atatgtgttg aatgaagaaa tgggtgaatg agcttgtcaa tgtgatttta 4981aaaaattgac tacctggagg aatgattagg aatctaaatg aagccagccc tcggtatctg 5041caggtttctc atccatggat tcaaccaact gcaaatggaa aatacgattt tttttaaaaa 5101aaggatggtt acatccgtat tgaacatgta cagacttttt tcttgtcatt attctctgaa 5161caatacaaga actctttatg tagcatttac atttattagg tattataagt aatctagaga 5221ttatttaatt aaaatataca ggaggatgtg tgtcagttat atgcaaattc tgtaccattt 5281tgtatcaggg aattgagcat cttcagatgt tggtatctgc agggatcctg gaaccaaacc 5341cctgcagata ctaagggctg acgatctagg taagactgga tttaacagtt ggaaaaaaaa 5401aaaaaaaagg agagagaaga cagttccttt cctgtagaaa ttaaaacaaa atacaaattg 5461aggaagctct gctacccagg ctgtcatggt agagaacttg aagaagacct gtttggatgg 5521acacctggtt tcaaaagtca ggtgtggaga ctgttaaatg ggagggcctc atccataaat 5581gatttctggc aacgtcttct tcaggtggag cttgacgtct ttttaatgtt acttggggag 5641ggagtgctca ttaagggatg ccagggccag ctctggtggt tcctggggag gctgcgtcct 5701tccctgcttc tgcatgtcat gaggcagcag gaaggtttcc cctgcacctg tctgtcctgg 5761ctccctctgg gtagccccct actgttctgt gcttcagcac agcctggttt gtcaagaggc 5821acatagttgg ggctgggctg catggcacag gggcttatgt gcctgctggt tatttaattt 5881tcagccttaa gttttcttta atattttcct gttggctatt taaaggtttt ggttatcttt 5941tattccttat ctacaatcaa gatgacaatg taattgaatt atcttattta taacacggtt 6001cgtgattcat gattcatgat tacaagtaga aaatatgtca tgttcctcac ctccaaataa 6061atatgtgtgt gtctgtgtgt gtgtatatat gtatgtggcg gagagggaga gagtggggaa 6121ggagagcagt gttatcatac atagagaggc taaatgtgtc ccatccctca ctgtcagctt 6181tataaaggag tttgactcca tccacagaag aatgttttat aagactagga aaacacgttg 6241aaaactagga taaacagcaa caaaaatcaa ctaaatatgt tgttactgtt gctaaggatt 6301ttctccttag aataatttag gatttttaaa aatttctgtt tgccaaatgc tgtagataaa 6361tggccagatt cttcctatcc ctaggattcc tttattattt tttttcacag attttgagaa 6421caagggggag agatagtatg gaagattaag attccattaa tcttatagaa ctgtgttgtc 6481acccaaattc ctgcttgttt gaacatggca tcttcataga ttcaggattc actaccctct 6541atagctggat cttgaaaatt atctggccag ataattttgc atctgcttgg atgattgtag 6601actgagatgt gagtggagga taaagtatta gacttttgct gagtaactgc caaccaagaa 6661gtatttatcg gacacttact aggtgcctag gattgtatca gagggaatat gaaatgtgtc 6721cctgccctac ctagttttaa cgacagaata tctattaaag gctacttagc tgaagggtaa 6781gggtgacagg tctaggggaa gctttgggag gtggtgtgct gtgacagaaa aagtggcaga 6841gtagggacga gagacctgca ttctagccct gtttctgtca cttgctctgt acacttagac 6901aacagcttga cctcttgagc tttagtttcc tcctctgcat aatgagaggg ttagactact 6961gaattgtatg ggaaaaaaat acaaattcct gggtcctagg ccatgcctgc tgaatccgac 7021tgttcaggaa gaggcctagg aaatctgtga gggaatcccc aggggaatct cgtgaccagc 7081caggtgtgaa atctgctaac tggaagatct caaagcttcc ttcacttttt gtgattttgt 7141ggtcatgtaa cgttactgta ttattctacg taaatgtggg tacttggatg tttatcatac 7201tgtttctctg tgtttacata ctaatttgtg taagaaatgc attttagtct gtgtacctca 7261acctgctgtt tgtttcctag aggtgttagt agtctttaaa tacaagtaag acttaagagg 7321atatttgatg ttatttacct ggatattttc ttcccctttt atttatttag aggaaattga 7381gattctagga gccaaaaaaa tgaaaacaaa attctaaggc aaagttaaag aaaaaaatta 7441cattatttct taccatttgc tactttataa tgaaaattta aaaattatat gggaagattt 7501ttctctggga taacaaatcc ttgtcataaa gtaagaggtc tttttaaagt aggtaggcta 7561taaggcctgt aatttaaaat aatactcctt tctctagggt ttggtgcaat tctccattaa 7621tgaagataac atttgaattc cccaaagcag gtgaggagtc ggggaggaga aagcgatgtt 7681aaaatgaaaa ctcactgcaa aagaggaggc agaggaagaa ggaatgtaaa ccccttaaag 7741cagatgtgtg tggggcctta tgaagaccag gattctgcgg gtgtcagggg attgcccctc 7801ttgacagaga ctagggtttt agactgaggc ttcctgcagg gtgttcgcat tgcccttctc 7861cgttcccctt cagacctttc tggggagaag aggtgggagg aggggagaaa gactgttcat 7921cttattctga atcctggagc agctgaaggt tttctcttga gtcaggatgc agtggtaatg 7981cattaaccag caagtgtggc caaggataat gaaaaagtgg gaaaggaagg tcctcctcct 8041ccctgattgt agcatccagc agtctctgta gccaggttac tcaagaacca catttgattt 8101cctggccctt tgccttggca gtgatggcat ttttatttca ctgtgtttta aagtcttcat 8161ttatttttat aacatgggtt agggagaagg gccacaaatg gagggattgt cctttcaagc 8221accacagctt cagataaaat tagtactttc aaatattgtc cactttaact taaaaaattc 8281tagagggatt atattggaga ctcaactgcc cttggtttta gtttataaaa tggcctagta 8341ctgtggaatt ttaattttag aaagtcttag catcagatca taaacattca ttaaaagaac 8401tcacatccca tctgaaactt cccaggggag ttgggattct tagtagattg gtagaaaggg 8461gctcattttc tactgcattt cccatttttg gtatcttgtt cagcatgttt tatttttatt 8521tcttgtctgc agaacatcct atatttatga gaacattctt taagaagacc accacataga 8581ataccccttc ctatcagctc gctctgattt agccttaatt ttgttaaatt ttttagagat 8641gaatgaagtg ctgctgtgga aagaaatgta catatactat ttctgtatca ttaaaattac 8701atttttatgg ttcaaaaaaa aaaaaaaaaaSEQ ID NO: 38 Human CYLD Isoform 2 Amino Acid Sequence (NP_001035814.1and NP_001035877.1) 1mssglwsqek vtspyweeri fylllqecsv tdkqtqkllk vpkgsigqyi qdrsvghsri 61psakgkknqi glkileqpha vlfvdekdvv einekftell laitnceerf slfknrnrls 121kglqidvgcp vkvqlrsgee kfpgvvrfrg pllaertvsg iffgvellee grgqgftdgv 181yqgkqlfqcd edcgvfvald kleliedddt alesdyagpg dtmqvelppl einsrvslkv 241getiesgtvi fcdvlpgkes lgyfvgvdmd npignwdgrf dgvqlcsfac vestillhin 301diipesvtqe rrppklafms rgvgdkgsss hnkpkatgst sdpgnrnrse lfytlngssv 361dsqpqskskn twyidevaed pakslteist drdrsspplq pppvnsltte nrfhslpfsl 421tkmpntngsi ghsplslsaq svmeelntap vqespplamp pgnshglevg slaevkenpp 481fygvirwigq ppglnevlag leledecagc tdgtfrgtry ftcalkkalf vklkscrpds 541rfaslqpvsn qiercnslaf ggylsevvee ntppkmekeg leimigkkkg iqghynscyl 601dstlfclfaf ssvldtvllr pkekndveyy setqellrte ivnplriygy vcatkimklr 661kilekveaas gftseekdpe eflnilfhhi lrvepllkir sagqkvqdcy fyqifmekne 721kvgvptiqql lewsfinsnl kfaeapscli iqmprfgkdf klfkkifpsl elnitdlled 781tprqcricgg lamyecrecy ddpdisagki kqfcktcntq vhlhpkrlnh kynpvslpkd 841lpdwdwrhgc ipcqnmelfa vlcietshyv afvkygkdds awlffdsmad rdggqngfni 901pqvtpcpevg eylkmsledl hsldsrriqg carrllcday mcmyqsptms lykSEQ ID NO: 39 Human CYLD transcript variant 2 cDNA sequence(NM_001042355,2; CDS: 243 . . . 3104) 1aggtagcagg tttggctgcg cgggggccgc gcgtcggagt ttcccccttt ctagggtgag 61gatggttcta cacagccacc cggagttcct tagttgaaag gtgcgccctg ctgtgacagc 121atggacacca cgttgctgaa aacatgcttt gggactgcca ctgaatttat cttttgcggt 181tttatgacaa agttattagt agtttccctt ttttgaatta gtattttgaa gttaatatca 241caatgagttc aggcttatgg agccaagaaa aagtcacttc accctactgg gaagagcgga 301ttttttactt gcttcttcaa gaatgcagcg ttacagacaa acaaacacaa aagctcctta 361aagtaccgaa gggaagtata ggacagtata ttcaagatcg ttctgtgggg cattcaagga 421ttccttctgc aaaaggcaag aaaaatcaga ttggattaaa aattctagag caacctcatg 481cagttctctt tgttgatgaa aaggatgttg tagagataaa tgaaaagttc acagagttac 541ttttggcaat taccaattgt gaggagaggt tcagcctgtt taaaaacaga aacagactaa 601gtaaaggcct ccaaatagac gtgggctgtc ctgtgaaagt acagctgaga tctggggaag 661aaaaatttcc tggagttgta cgcttcagag gacccctgtt agcagagagg acagtctccg 721gaatattctt tggagttgaa ttgctggaag aaggtcgtgg tcaaggtttc actgacgggg 781tgtaccaagg gaaacagctt tttcagtgtg atgaagattg tggcgtgttt gttgcattgg 841acaagctaga actcatagaa gatgatgaca ctgcattgga aagtgattac gcaggtcctg 901gggacacaat gcaggtcgaa cttcctcctt tggaaataaa ctccagagtt tctttgaagg 961ttggagaaac aatagaatct ggaacagtta tattctgtga tgttttgcca ggaaaagaaa 1021gcttaggata ttttgttggt gtggacatgg ataaccctat tggcaactgg gatggaagat 1081ttgatggagt gcagctttgt agttttgcgt gtgttgaaag tacaattcta ttgcacatca 1141atgatatcat cccagagagt gtgacgcagg aaaggaggcc tcccaaactt gcctttatgt 1201caagaggtgt tggggacaaa ggttcatcca gtcataataa accaaaggct acaggatcta 1261cctcagaccc tggaaataga aacagatctg aattatttta taccttaaat gggtcttctg 1321ttgactcaca accacaatcc aaatcaaaaa atacatggta cattgatgaa gttgcagaag 1381accctgcaaa atctcttaca gagatatcta cagactttga ccgttcttca ccaccactcc 1441agcctcctcc tgtgaactca ctgaccaccg agaacagatt ccactcttta ccattcagtc 1501tcaccaagat gcccaatacc aatggaagta ttggccacag tccactttct ctgtcagccc 1561agtctgtaat ggaagagcta aacactgcac ccgtccaaga gagtccaccc ttggccatgc 1621ctcctgggaa ctcacatggt ctagaagtgg gctcattggc tgaagttaag gagaaccctc 1681ctttctatgg ggtaatccgt tggatcggtc agccaccagg actgaatgaa gtgctcgctg 1741gactggaact ggaagatgag tgtgcaggct gtacggatgg aaccttcaga ggcactcggt 1801atttcacctg tgccctgaag aaggcgctgt ttgtgaaact gaagagctgc aggcctgact 1861ctaggtttgc atcattgcag ccggtttcca atcagattga gcgctgtaac tctttagcat 1921ttggaggcta cttaagtgaa gtagtagaag aaaatactcc accaaaaatg gaaaaagaag 1981gcttggagat aatgattggg aagaagaaag gcatccaggg tcattacaat tcttgttact 2041tagactcaac cttattctgc ttatttgctt ttagttctgt tctggacact gtgttactta 2101gacccaaaga aaagaacgat gtagaatatt atagtgaaac ccaagagcta ctgaggacag 2161aaattgttaa tcctctgaga atatatggat atgtgtgtgc cacaaaaatt atgaaactga 2221ggaaaatact tgaaaaggtg gaggctgcat caggatttac ctctgaagaa aaagatcctg 2281aggaattctt gaatattctg tttcatcata ttttaagggt agaacctttg ctaaaaataa 2341gatcagcagg tcaaaaggta caagattgtt acttctatca aatttttatg gaaaaaaatg 2401agaaagttgg cgttcccaca attcagcagt tgttagaatg gtcttttatc aacagtaacc 2461tgaaatttgc agaggcacca tcatgtctga ttattcagat gcctcgattt ggaaaagact 2521ttaaactatt taaaaaaatt tttccttctc tggaattaaa tataacagat ttacttgaag 2581acactcccag acagtgccgg atatgtggag ggcttgcaat gtatgagtgt agagaatgct 2641acgacgatcc ggacatctca gctggaaaaa tcaagcagtt ttgtaaaacc tgcaacactc 2701aagtccacct tcatccgaag aggctgaatc ataaatataa cccagtgtca cttcccaaag 2761acttacccga ctgggactgg agacacggct gcatcccttg ccagaatatg gagttatttg 2821ctgttctctg catagaaaca agccactatg ttgcttttgt gaagtatggg aaggacgatt 2881ctgcctggct cttctttgac agcatggccg atcgggatgg tggtcagaat ggcttcaaca 2941ttcctcaagt caccccatgc ccagaagtag gagagtactt gaagatgtct ctggaagacc 3001tgcattcctt ggactccagg agaatccaag gctgtgcacg aagactgctt tgtgatgcat 3061atatgtgcat gtaccagagt ccaacaatga gtttgtacaa ataactgggg tcatcgggaa 3121aggcaaagaa actgaaggca gagtcctaac gttgcatctt attcgagctg gcagttctgt 3181tcacgtccat tgccggcaat ggatgtcttt gtggtgatga tccttcagaa aaggatgcct 3241ctgtttaaaa acaaattgct tttgtgtccc tgaagtattt aataagaagc attttgcact 3301ctagaaagta tgtttgtgtt ggttttttaa gaagtctaaa tgaagttatt aatacctgaa 3361gctttaagtt aagtgcattg atcatatgat atttttggaa gcatacaatt ttaattgtgg 3421aagtttaaag cctcttttag tccattgaga atgtaaataa atgtgtcttc tttatggacc 3481aaggatatga aatcattttt cttttgtagc taacggttgc cttgaggaag aaataatttg 3541gttttattaa gagtctactc tcaatccagt tattagagat gtactgagtt tgatttgtta 3601atcctttcta tatactgctg atcttgcatg tctacaatct gctcagtttt tctgtgtttc 3661tgcaatagtg gtcagaaaaa tacttaaatt cccttaatgg tgttgttttc tatttgttct 3721ggttttgaga taaatgagtg attctgtccc caaatgtcca tttttgaagt gattttcctg 3781gaggattagg gtatttagca gttgaagctc ttcattcata gtagttactg tcagctaaca 3841ggttttttaa ggcttttaac tattaatatt ttatggaatg gggcaaagta aattgatgaa 3901agaattggag tgataatagt cctttacaaa catacagtcc ataagaaaat gaatttggca 3961tatagaatta ttacaatttc ctgggagaga tggatattta aacctctatt attttagaca 4021agactgtcta gaacttaagt ttgatctgtc agccagtact cccattaaat tcagtgtagt 4081ttcacttgat agaatcagat atgttatcga aatgttagca gcagcttcat cctccttctg 4141attaaagtaa gtagaaatgg gatgttttgt ttaataacag ccatagtgtg tgtttagacc 4201acagcggatg ttgtagacca ggaccataga tgatacatgt cagtgctgtg gaatgtgcat 4261tctctgagtg ttgttttgtg gtatcattgt ctttcctgaa tgactttcta actgtgcaga 4321aaggcagaaa agtcatcata tgtatatgtc atatgacttt ataaaatatt taatgtgaca 4381aaaagtggaa agaatcttta caaaccctgc aattactttt ttaaaggcac ttttactctt 4441tggttttatc attccatttt gctaatattt actagcttta taaattacag taaggtacaa 4501aaactcatct tgtaatattt tcatttttga agtgaaaaag tacatatatt ttgcacaagg 4561ttttatactg ctaagtgctt ggttggggtg gtgagatgat gattagatca ggggtgaggc 4621tgagagactc tgggtttagg gctagccctg cctccatctc ccttgggtaa aatgaagggt 4681gtggggtaaa agatgcataa ggccttttct agctctgaca gcctagaagt ccaatcaccc 4741tgtaataaat atgtgttgaa tgaagaaatg ggtgaatgag cttgtcaatg tgattttaaa 4801aaattgacta cctggaggaa tgattaggaa tctaaatgaa gccagccctc ggtatctgca 4861ggtttctcat ccatggattc aaccaactgc aaatggaaaa tacgattttt tttaaaaaaa 4921ggatggttac atccgtattg aacatgtaca gacttttttc ttgtcattat tctctgaaca 4981atacaagaac tctttatgta gcatttacat ttattaggta ttataagtaa tctagagatt 5041atttaattaa aatatacagg aggatgtgtg tcagttatat gcaaattctg taccattttg 5101tatcagggaa ttgagcatct tcagatgttg gtatctgcag ggatcctgga accaaacccc 5161tgcagatact aagggctgac gatctaggta agactggatt taacagttgg aaaaaaaaaa 5221aaaaaaggag agagaagaca gttcctttcc tgtagaaatt aaaacaaaat acaaattgag 5281gaagctctgc tacccaggct gtcatggtag agaacttgaa gaagacctgt ttggatggac 5341acctggtttc aaaagtcagg tgtggagact gttaaatggg agggcctcat ccataaatga 5401tttctggcaa cgtcttcttc aggtggagct tgacgtcttt ttaatgttac ttggggaggg 5461agtgctcatt aagggatgcc agggccagct ctggtggttc ctggggaggc tgcgtccttc 5521cctgcttctg catgtcatga ggcagcagga aggtttcccc tgcacctgtc tgtcctggct 5581ccctctgggt agccccctac tgttctgtgc ttcagcacag cctggtttgt caagaggcac 5641atagttgggg ctgggctgca tggcacaggg gcttatgtgc ctgctggtta tttaattttc 5701agccttaagt tttctttaat attttcctgt tggctattta aaggttttgg ttatctttta 5761ttccttatct acaatcaaga tgacaatgta attgaattat cttatttata acacggttcg 5821tgattcatga ttcatgatta caagtagaaa atatgtcatg ttcctcacct ccaaataaat 5881atgtgtgtgt ctgtgtgtgt gtatatatgt atgtggcgga gagggagaga gtggggaagg 5941agagcagtgt tatcatacat agagaggcta aatgtgtccc atccctcact gtcagcttta 6001taaaggagtt tgactccatc cacagaagaa tgttttataa gactaggaaa acacgttgaa 6061aactaggata aacagcaaca aaaatcaact aaatatgttg ttactgttgc taaggatttt 6121ctccttagaa taatttagga tttttaaaaa tttctgtttg ccaaatgctg tagataaatg 6181gccagattct tcctatccct aggattcctt tattattttt tttcacagat tttgagaaca 6241agggggagag atagtatgga agattaagat tccattaatc ttatagaact gtgttgtcac 6301ccaaattcct gcttgtttga acatggcatc ttcatagatt caggattcac taccctctat 6361agctggatct tgaaaattat ctggccagat aattttgcat ctgcttggat gattgtagac 6421tgagatgtga gtggaggata aagtattaga cttttgctga gtaactgcca accaagaagt 6481atttatcgga cacttactag gtgcctagga ttgtatcaga gggaatatga aatgtgtccc 6541tgccctacct agttttaacg acagaatatc tattaaaggc tacttagctg aagggtaagg 6601gtgacaggtc taggggaagc tttgggaggt ggtgtgctgt gacagaaaaa gtggcagagt 6661agggacgaga gacctgcatt ctagccctgt ttctgtcact tgctctgtac acttagacaa 6721cagcttgacc tcttgagctt tagtttcctc ctctgcataa tgagagggtt agactactga 6781attgtatggg aaaaaaatac aaattcctgg gtcctaggcc atgcctgctg aatccgactg 6841ttcaggaaga ggcctaggaa atctgtgagg gaatccccag gggaatctcg tgaccagcca 6901ggtgtgaaat ctgctaactg gaagatctca aagcttcctt cactttttgt gattttgtgg 6961tcatgtaacg ttactgtatt attctacgta aatgtgggta cttggatgtt tatcatactg 7021tttctctgtg tttacatact aatttgtgta agaaatgcat tttagtctgt gtacctcaac 7081ctgctgtttg tttcctagag gtgttagtag tctttaaata caagtaagac ttaagaggat 7141atttgatgtt atttacctgg atattttctt ccccttttat ttatttagag gaaattgaga 7201ttctaggagc caaaaaaatg aaaacaaaat tctaaggcaa agttaaagaa aaaaattaca 7261ttatttctta ccatttgcta ctttataatg aaaatttaaa aattatatgg gaagattttt 7321ctctgggata acaaatcctt gtcataaagt aagaggtctt tttaaagtag gtaggctata 7381aggcctgtaa tttaaaataa tactcctttc tctagggttt ggtgcaattc tccattaatg 7441aagataacat ttgaattccc caaagcaggt gaggagtcgg ggaggagaaa gcgatgttaa 7501aatgaaaact cactgcaaaa gaggaggcag aggaagaagg aatgtaaacc ccttaaagca 7561gatgtgtgtg gggccttatg aagaccagga ttctgcgggt gtcaggggat tgcccctctt 7621gacagagact agggttttag actgaggctt cctgcagggt gttcgcattg cccttctccg 7681ttccccttca gacctttctg gggagaagag gtgggaggag gggagaaaga ctgttcatct 7741tattctgaat cctggagcag ctgaaggttt tctcttgagt caggatgcag tggtaatgca 7801ttaaccagca agtgtggcca aggataatga aaaagtggga aaggaaggtc ctcctcctcc 7861ctgattgtag catccagcag tctctgtagc caggttactc aagaaccaca tttgatttcc 7921tggccctttg ccttggcagt gatggcattt ttatttcact gtgttttaaa gtcttcattt 7981atttttataa catgggttag ggagaagggc cacaaatgga gggattgtcc tttcaagcac 8041cacagcttca gataaaatta gtactttcaa atattgtcca ctttaactta aaaaattcta 8101gagggattat attggagact caactgccct tggttttagt ttataaaatg gcctagtact 8161gtggaatttt aattttagaa agtcttagca tcagatcata aacattcatt aaaagaactc 8221acatcccatc tgaaacttcc caggggagtt gggattctta gtagattggt agaaaggggc 8281tcattttcta ctgcatttcc catttttggt atcttgttca gcatgtttta tttttatttc 8341ttgtctgcag aacatcctat atttatgaga acattcttta agaagaccac cacatagaat 8401accccttcct atcagctcgc tctgatttag ccttaatttt gttaaatttt ttagagatga 8461atgaagtgct gctgtggaaa gaaatgtaca tatactattt ctgtatcatt aaaattacat 8521ttttatggtt c SEQ ID NO: 40 Human CYLD transcript variant 3 cDNA sequence(NM_001042412,2; CDS: 335. . . 3196) 1aggtagcagg tttggctgcg cgggggccgc gcgtcggagg taaatactag ggcggtgggt 61gtggggagcc ggggccggcc cgggacgcgg gctggggagc cggggcgagg ggcgacgccc 121cgccgcccga gtttccccct ttctagggtg aggatggttc tacacagcca cccggagttc 181cttagttgaa aggtgcgccc tgctgtgaca gcatggacac cacgttgctg aaaacatgct 241ttgggactgc cactgaattt atcttttgcg gttttatgac aaagttatta gtagtttccc 301ttttttgaat tagtattttg aagttaatat cacaatgagt tcaggcttat ggagccaaga 361aaaagtcact tcaccctact gggaagagcg gattttttac ttgcttcttc aagaatgcag 421cgttacagac aaacaaacac aaaagctcct taaagtaccg aagggaagta taggacagta 481tattcaagat cgttctgtgg ggcattcaag gattccttct gcaaaaggca agaaaaatca 541gattggatta aaaattctag agcaacctca tgcagttctc tttgttgatg aaaaggatgt 601tgtagagata aatgaaaagt tcacagagtt acttttggca attaccaatt gtgaggagag 661gttcagcctg tttaaaaaca gaaacagact aagtaaaggc ctccaaatag acgtgggctg 721tcctgtgaaa gtacagctga gatctgggga agaaaaattt cctggagttg tacgcttcag 781aggacccctg ttagcagaga ggacagtctc cggaatattc tttggagttg aattgctgga 841agaaggtcgt ggtcaaggtt tcactgacgg ggtgtaccaa gggaaacagc tttttcagtg 901tgatgaagat tgtggcgtgt ttgttgcatt ggacaagcta gaactcatag aagatgatga 961cactgcattg gaaagtgatt acgcaggtcc tggggacaca atgcaggtcg aacttcctcc 1021tttggaaata aactccagag tttctttgaa ggttggagaa acaatagaat ctggaacagt 1081tatattctgt gatgttttgc caggaaaaga aagcttagga tattttgttg gtgtggacat 1141ggataaccct attggcaact gggatggaag atttgatgga gtgcagcttt gtagttttgc 1201gtgtgttgaa agtacaattc tattgcacat caatgatatc atcccagaga gtgtgacgca 1261ggaaaggagg cctcccaaac ttgcctttat gtcaagaggt gttggggaca aaggttcatc 1321cagtcataat aaaccaaagg ctacaggatc tacctcagac cctggaaata gaaacagatc 1381tgaattattt tataccttaa atgggtcttc tgttgactca caaccacaat ccaaatcaaa 1441aaatacatgg tacattgatg aagttgcaga agaccctgca aaatctctta cagagatatc 1501tacagacttt gaccgttctt caccaccact ccagcctcct cctgtgaact cactgaccac 1561cgagaacaga ttccactctt taccattcag tctcaccaag atgcccaata ccaatggaag 1621tattggccac agtccacttt ctctgtcagc ccagtctgta atggaagagc taaacactgc 1681acccgtccaa gagagtccac ccttggccat gcctcctggg aactcacatg gtctagaagt 1741gggctcattg gctgaagtta aggagaaccc tcctttctat ggggtaatcc gttggatcgg 1801tcagccacca ggactgaatg aagtgctcgc tggactggaa ctggaagatg agtgtgcagg 1861ctgtacggat ggaaccttca gaggcactcg gtatttcacc tgtgccctga agaaggcgct 1921gtttgtgaaa ctgaagagct gcaggcctga ctctaggttt gcatcattgc agccggtttc 1981caatcagatt gagcgctgta actctttagc atttggaggc tacttaagtg aagtagtaga 2041agaaaatact ccaccaaaaa tggaaaaaga aggcttggag ataatgattg ggaagaagaa 2101aggcatccag ggtcattaca attcttgtta cttagactca accttattct gcttatttgc 2161ttttagttct gttctggaca ctgtgttact tagacccaaa gaaaagaacg atgtagaata 2221ttatagtgaa acccaagagc tactgaggac agaaattgtt aatcctctga gaatatatgg 2281atatgtgtgt gccacaaaaa ttatgaaact gaggaaaata cttgaaaagg tggaggctgc 2341atcaggattt acctctgaag aaaaagatcc tgaggaattc ttgaatattc tgtttcatca 2401tattttaagg gtagaacctt tgctaaaaat aagatcagca ggtcaaaagg tacaagattg 2461ttacttctat caaattttta tggaaaaaaa tgagaaagtt ggcgttccca caattcagca 2521gttgttagaa tggtctttta tcaacagtaa cctgaaattt gcagaggcac catcatgtct 2581gattattcag atgcctcgat ttggaaaaga ctttaaacta tttaaaaaaa tttttccttc 2641tctggaatta aatataacag atttacttga agacactccc agacagtgcc ggatatgtgg 2701agggcttgca atgtatgagt gtagagaatg ctacgacgat ccggacatct cagctggaaa 2761aatcaagcag ttttgtaaaa cctgcaacac tcaagtccac cttcatccga agaggctgaa 2821tcataaatat aacccagtgt cacttcccaa agacttaccc gactgggact ggagacacgg 2881ctgcatccct tgccagaata tggagttatt tgctgttctc tgcatagaaa caagccacta 2941tgttgctttt gtgaagtatg ggaaggacga ttctgcctgg ctcttctttg acagcatggc 3001cgatcgggat ggtggtcaga atggcttcaa cattcctcaa gtcaccccat gcccagaagt 3061aggagagtac ttgaagatgt ctctggaaga cctgcattcc ttggactcca ggagaatcca 3121aggctgtgca cgaagactgc tttgtgatgc atatatgtgc atgtaccaga gtccaacaat 3181gagtttgtac aaataactgg ggtcatcggg aaaggcaaag aaactgaagg cagagtccta 3241acgttgcatc ttattcgagc tggcagttct gttcacgtcc attgccggca atggatgtct 3301ttgtggtgat gatccttcag aaaaggatgc ctctgtttaa aaacaaattg cttttgtgtc 3361cctgaagtat ttaataagaa gcattttgca ctctagaaag tatgtttgtg ttggtttttt 3421aagaagtcta aatgaagtta ttaatacctg aagctttaag ttaagtgcat tgatcatatg 3481atatttttgg aagcatacaa ttttaattgt ggaagtttaa agcctctttt agtccattga 3541gaatgtaaat aaatgtgtct tctttatgga ccaaggatat gaaatcattt ttcttttgta 3601gctaacggtt gccttgagga agaaataatt tggttttatt aagagtctac tctcaatcca 3661gttattagag atgtactgag tttgatttgt taatcctttc tatatactgc tgatcttgca 3721tgtctacaat ctgctcagtt tttctgtgtt tctgcaatag tggtcagaaa aatacttaaa 3781ttcccttaat ggtgttgttt tctatttgtt ctggttttga gataaatgag tgattctgtc 3841cccaaatgtc catttttgaa gtgattttcc tggaggatta gggtatttag cagttgaagc 3901tcttcattca tagtagttac tgtcagctaa caggtttttt aaggctttta actattaata 3961ttttatggaa tggggcaaag taaattgatg aaagaattgg agtgataata gtcctttaca 4021aacatacagt ccataagaaa atgaatttgg catatagaat tattacaatt tcctgggaga 4081gatggatatt taaacctcta ttattttaga caagactgtc tagaacttaa gtttgatctg 4141tcagccagta ctcccattaa attcagtgta gtttcacttg atagaatcag atatgttatc 4201gaaatgttag cagcagcttc atcctccttc tgattaaagt aagtagaaat gggatgtttt 4261gtttaataac agccatagtg tgtgtttaga ccacagcgga tgttgtagac caggaccata 4321gatgatacat gtcagtgctg tggaatgtgc attctctgag tgttgttttg tggtatcatt 4381gtctttcctg aatgactttc taactgtgca gaaaggcaga aaagtcatca tatgtatatg 4441tcatatgact ttataaaata tttaatgtga caaaaagtgg aaagaatctt tacaaaccct 4501gcaattactt ttttaaaggc acttttactc tttggtttta tcattccatt ttgctaatat 4561ttactagctt tataaattac agtaaggtac aaaaactcat cttgtaatat tttcattttt 4621gaagtgaaaa agtacatata ttttgcacaa ggttttatac tgctaagtgc ttggttgggg 4681tggtgagatg atgattagat caggggtgag gctgagagac tctgggttta gggctagccc 4741tgcctccatc tcccttgggt aaaatgaagg gtgtggggta aaagatgcat aaggcctttt 4801ctagctctga cagcctagaa gtccaatcac cctgtaataa atatgtgttg aatgaagaaa 4861tgggtgaatg agcttgtcaa tgtgatttta aaaaattgac tacctggagg aatgattagg 4921aatctaaatg aagccagccc tcggtatctg caggtttctc atccatggat tcaaccaact 4981gcaaatggaa aatacgattt tttttaaaaa aaggatggtt acatccgtat tgaacatgta 5041cagacttttt tcttgtcatt attctctgaa caatacaaga actctttatg tagcatttac 5101atttattagg tattataagt aatctagaga ttatttaatt aaaatataca ggaggatgtg 5161tgtcagttat atgcaaattc tgtaccattt tgtatcaggg aattgagcat cttcagatgt 5221tggtatctgc agggatcctg gaaccaaacc cctgcagata ctaagggctg acgatctagg 5281taagactgga tttaacagtt ggaaaaaaaa aaaaaaaagg agagagaaga cagttccttt 5341cctgtagaaa ttaaaacaaa atacaaattg aggaagctct gctacccagg ctgtcatggt 5401agagaacttg aagaagacct gtttggatgg acacctggtt tcaaaagtca ggtgtggaga 5461ctgttaaatg ggagggcctc atccataaat gatttctggc aacgtcttct tcaggtggag 5521cttgacgtct ttttaatgtt acttggggag ggagtgctca ttaagggatg ccagggccag 5581ctctggtggt tcctggggag gctgcgtcct tccctgcttc tgcatgtcat gaggcagcag 5641gaaggtttcc cctgcacctg tctgtcctgg ctccctctgg gtagccccct actgttctgt 5701gcttcagcac agcctggttt gtcaagaggc acatagttgg ggctgggctg catggcacag 5761gggcttatgt gcctgctggt tatttaattt tcagccttaa gttttcttta atattttcct 5821gttggctatt taaaggtttt ggttatcttt tattccttat ctacaatcaa gatgacaatg 5881taattgaatt atcttattta taacacggtt cgtgattcat gattcatgat tacaagtaga 5941aaatatgtca tgttcctcac ctccaaataa atatgtgtgt gtctgtgtgt gtgtatatat 6001gtatgtggcg gagagggaga gagtggggaa ggagagcagt gttatcatac atagagaggc 6061taaatgtgtc ccatccctca ctgtcagctt tataaaggag tttgactcca tccacagaag 6121aatgttttat aagactagga aaacacgttg aaaactagga taaacagcaa caaaaatcaa 6181ctaaatatgt tgttactgtt gctaaggatt ttctccttag aataatttag gatttttaaa 6241aatttctgtt tgccaaatgc tgtagataaa tggccagatt cttcctatcc ctaggattcc 6301tttattattt tttttcacag attttgagaa caagggggag agatagtatg gaagattaag 6361attccattaa tcttatagaa ctgtgttgtc acccaaattc ctgcttgttt gaacatggca 6421tcttcataga ttcaggattc actaccctct atagctggat cttgaaaatt atctggccag 6481ataattttgc atctgcttgg atgattgtag actgagatgt gagtggagga taaagtatta 6541gacttttgct gagtaactgc caaccaagaa gtatttatcg gacacttact aggtgcctag 6601gattgtatca gagggaatat gaaatgtgtc cctgccctac ctagttttaa cgacagaata 6661tctattaaag gctacttagc tgaagggtaa gggtgacagg tctaggggaa gctttgggag 6721gtggtgtgct gtgacagaaa aagtggcaga gtagggacga gagacctgca ttctagccct 6781gtttctgtca cttgctctgt acacttagac aacagcttga cctcttgagc tttagtttcc 6841tcctctgcat aatgagaggg ttagactact gaattgtatg ggaaaaaaat acaaattcct 6901gggtcctagg ccatgcctgc tgaatccgac tgttcaggaa gaggcctagg aaatctgtga 6961gggaatcccc aggggaatct cgtgaccagc caggtgtgaa atctgctaac tggaagatct 7021caaagcttcc ttcacttttt gtgattttgt ggtcatgtaa cgttactgta ttattctacg 7081taaatgtggg tacttggatg tttatcatac tgtttctctg tgtttacata ctaatttgtg 7141taagaaatgc attttagtct gtgtacctca acctgctgtt tgtttcctag aggtgttagt 7201agtctttaaa tacaagtaag acttaagagg atatttgatg ttatttacct ggatattttc 7261ttcccctttt atttatttag aggaaattga gattctagga gccaaaaaaa tgaaaacaaa 7321attctaaggc aaagttaaag aaaaaaatta cattatttct taccatttgc tactttataa 7381tgaaaattta aaaattatat gggaagattt ttctctggga taacaaatcc ttgtcataaa 7441gtaagaggtc tttttaaagt aggtaggcta taaggcctgt aatttaaaat aatactcctt 7501tctctagggt ttggtgcaat tctccattaa tgaagataac atttgaattc cccaaagcag 7561gtgaggagtc ggggaggaga aagcgatgtt aaaatgaaaa ctcactgcaa aagaggaggc 7621agaggaagaa ggaatgtaaa ccccttaaag cagatgtgtg tggggcctta tgaagaccag 7681gattctgcgg gtgtcagggg attgcccctc ttgacagaga ctagggtttt agactgaggc 7741ttcctgcagg gtgttcgcat tgcccttctc cgttcccctt cagacctttc tggggagaag 7801aggtgggagg aggggagaaa gactgttcat cttattctga atcctggagc agctgaaggt 7861tttctcttga gtcaggatgc agtggtaatg cattaaccag caagtgtggc caaggataat 7921gaaaaagtgg gaaaggaagg tcctcctcct ccctgattgt agcatccagc agtctctgta 7981gccaggttac tcaagaacca catttgattt cctggccctt tgccttggca gtgatggcat 8041ttttatttca ctgtgtttta aagtcttcat ttatttttat aacatgggtt agggagaagg 8101gccacaaatg gagggattgt cctttcaagc accacagctt cagataaaat tagtactttc 8161aaatattgtc cactttaact taaaaaattc tagagggatt atattggaga ctcaactgcc 8221cttggtttta gtttataaaa tggcctagta ctgtggaatt ttaattttag aaagtcttag 8281catcagatca taaacattca ttaaaagaac tcacatccca tctgaaactt cccaggggag 8341ttgggattct tagtagattg gtagaaaggg gctcattttc tactgcattt cccatttttg 8401gtatcttgtt cagcatgttt tatttttatt tcttgtctgc agaacatcct atatttatga 8461gaacattctt taagaagacc accacataga ataccccttc ctatcagctc gctctgattt 8521agccttaatt ttgttaaatt ttttagagat gaatgaagtg ctgctgtgga aagaaatgta 8581catatactat ttctgtatca ttaaaattac atttttatgg ttcSEQ ID NO: 41 Mouse CYLD Isoform 1 Amino Acid Sequence (NP_001121642.1)1 mssglwsqek vtspyweeri fylllqecsv tdkqtqkllk vpkgsigqyi qdrsvghsrv 61pstkgkknqi glkileqpha vlfvdekdvv einekftell laitnceerl slfrnrlrls 121kglqvdvgsp vkvqlrsgee kfpgvvrfrg pllaertvsg iffgvellee grgqgftdgv 181yqqkqlfqcd edcgvfvald kleliedddn glesdfagpg dtmqvepppl einsrvslkv 241gestesgtvi fedvlpgkes lgyfvgvdmd npignwdgrf dgvqlcsfas vestillhin 301diipalsdsv tqerrppkla fmsrgvgdkg ssshnkpkvt gstsdpgsrn rselfytlng 361ssvdsqqsks knpwyideva edpaksltem ssdfghsspp pqppsmnsls senrfhslpf 421sltkmpntng smahsplsls vqsvmgelns tpvqespplp issgnahgle vgslaevken 481ppfygvirwi gqppglsdvl agleledeca gctdgtfrgt ryftcalkka lfvklkscrp 541dsrfaslqpv snqiercnsl afggylsevv eentppkmek egleimigkk kgiqghynsc 601yldstlfclf afssaldtvl lrpkekndie yysetqellr teivnplriy gyvcatkimk 661lrkilekvea asgftseekd peeflnilfh dilrvepllk irsagqkvqd cnfyqifmek 721nekvgvptiq qllewsfins nlkfaeapsc liiqmprfgk dfklfkkifp slelnitdll 781edtprqcric gglamyecre cyddpdisag kikqfcktcs tqvhlhprrl nhsyhpvslp 841kdlpdwdwrh gcipcqkmel favlcietsh yvafvkygkd dsawlffdsm adrdggqngf 901nipqvtpcpe vgeylkmsle dlhsldsrri qgcarrllcd aymcmyqspt mslykSEQ ID NO: 42 Mouse CYLD transcript variant 1 cDNA sequence(NM_001128170.2; CDS: 223 . . . 3090) 1agttcggagg cggggcaggt gggggcgggc ccaggtagca ggttcggctg cgcgggggcc 61cgcgcgcctg aggcactttg aattgctgtc tttttacaac atggatgcca ggttgctaaa 121atcttgcttt gggacttaca gcgagttcat ttttttggat tttatgacag atttactagt 181ggctcctttt tgccagtcaa tgttctgaaa gttactgtca caatgagttc aggcctgtgg 241agccaagaga aagttacttc accctactgg gaagaacgga ttttttatct gcttcttcaa 301gaatgcagtg taacagacaa acaaactcag aagctgctga aagtacccaa agggagtata 361ggacagtaca tccaagaccg ttctgtgggg cattcaagag ttccttccac aaaaggcaag 421aaaaatcaga ttggattaaa aatcttggag caaccgcatg cagttctgtt tgttgatgaa 481aaggatgttg tagaaataaa tgaaaaattc acagagttac tgttggcaat taccaactgt 541gaggagaggc tcagcctatt tagaaacaga ctccgactaa gtaaaggcct ccaggtagac 601gtgggcagtc ctgtgaaagt acagctgcga tctggggaag agaaatttcc aggagttgta 661cgcttcagag gacctttatt agcggagagg acggtgtcgg ggattttctt tggagtagaa 721ttattggaag aaggtcgtgg tcaaggtttc acggatgggg tatatcaagg gaagcagctt 781ttccagtgtg atgaggactg tggcgtgttt gttgcattgg acaaactaga acttatagaa 841gatgatgaca atggattgga aagtgatttt gcaggcccag gagatacaat gcaggttgaa 901cctccccctt tggaaataaa ctccagagtt tctttgaagg ttggagaaag tacagaatct 961ggaacagtaa tattctgtga tgttttacca ggaaaagaga gtctaggata ttttgttggt 1021gtggacatgg ataaccctat tggcaactgg gatggaaggt ttgatggagt acagctctgt 1081agttttgcaa gtgttgaaag tacaattctc ctgcacatca atgacatcat cccagcttta 1141tcagatagcg tgacacagga aaggaggcct cccaaacttg cctttatgtc aagaggtgta 1201ggtgacaaag gttcatctag tcataataaa ccaaaggtta caggatctac ctcagaccct 1261ggaagtagaa acagatctga attattttat accttaaatg ggtcatctgt tgactcacaa 1321caatccaagt ccaaaaatcc atggtacatt gatgaagttg cagaagaccc tgcaaagtca 1381cttacagaga tgtcttcgga cttcggacat tcatctcctc caccgcagcc tccttccatg 1441aactccttgt ctagcgagaa cagattccac tccttaccct tcagcctgac aaagatgccc 1501aatactaatg gcagcatggc tcatagtcca ctctctctgt cagtgcagtc tgtgatgggg 1561gagctgaaca gcacacctgt ccaggagagt ccacccttgc ccatctcttc tgggaatgca 1621cacgggctag aggtgggctc actggctgaa gtaaaagaga accccccgtt ctatggggtt 1681atccgttgga ttggccagcc accagggctc agtgacgtgc tagctggact ggaactggaa 1741gatgaatgcg caggctgtac agatggaact ttcaggggca cgcggtattt cacgtgtgcc 1801ctgaagaagg cactgtttgt gaaactgaag agctgcagac cggactctag gtttgcatcc 1861ttgcagcctg tttccaatca aattgaaagg tgtaactctt tagcatttgg gggctattta 1921agtgaagtag tagaagaaaa tactccacct aaaatggaaa aggaaggttt agagataatg 1981attggaaaga agaaaggcat ccagggccat tacaattctt gttacttaga ctcaacttta 2041ttctgcttat ttgcttttag ttctgccctg gacactgtgt tacttagacc caaagagaag 2101aatgatatag agtattacag tgagactcag gagctactga ggacagagat agtcaatcct 2161ctgagaatat atggatatgt gtgtgccaca aagattatga aactgaggaa aatacttgaa 2221aaagttgagg ctgcatcagg ttttacctct gaagaaaaag atcctgaaga attcttaaat 2281atcctgtttc atgatatttt aagggttgaa ccattgttaa aaataagatc agcaggtcaa 2341aaagttcaag actgtaactt ctatcaaatt tttatggaaa aaaatgagaa agttggagta 2401cccacaattc agcagttatt agaatggtct tttatcaaca gcaacctgaa atttgcagag 2461gcaccatcat gcttgattat ccagatgcct cggtttggaa aagactttaa actatttaaa 2521aaaatttttc cttccctgga attaaatata acagatttac ttgaagacac tcccaggcag 2581tgccgcatct gtggaggact tgcgatgtac gagtgcaggg agtgctatga cgatccggac 2641atctcagctg ggaagatcaa gcagttctgt aagacctgca gcactcaggt tcaccttcat 2701cccaggaggt tgaatcattc ttatcatcca gtatcacttc ccaaagactt gcctgactgg 2761gactggagac acggctgcat cccctgtcag aagatggagt tatttgctgt tctctgcata 2821gaaacgagcc actatgttgc ttttgtgaag tatgggaagg atgactctgc ctggcttttc 2881tttgacagca tggcggatcg agatggtggt cagaatggct tcaacattcc acaagtgacg 2941ccctgcccag aagtgggaga gtacttgaag atgtctctgg aggacctgca ctctttggat 3001tccagaagga ttcaaggctg tgcgcgcaga cttctttgcg atgcatacat gtgcatgtac 3061cagagtccaa ccatgagcct gtacaaataa ccaggttatc cgcagtgggc agagacagca 3121caaaccttag tgctgtgtct tcctccagct tgtggttctg tccggcaccc attgccggca 3181atgggtgtct cttttgatga tggcccttca gcaaaggatt cctgtgtttc caaacaaatt 3241gcttttgtgt tcctgaagta tttaataaga agcattttgc actctaggaa gtatgtttgt 3301gttgattttt taagaagtct aaatggattt attaatatct gacactttaa gttaactgca 3361ttgatgatac gatatttttg gaagcataca attttaattg tgacgtctaa aacctctttt 3421agtccattga ggatgtaaat aaatatttct tcttatggac cagggatatg aaatcatttt 3481ccttttgtag ctaatgattg ccttgagaaa gacataatat gattttatta agagtctgcc 3541tttactccaa ttgttgaagg tgtgctgagt ttaattgtta attttcctat atagtgctga 3601tttcctgcat gtctgtactt tgctgagttt ctgtgttcct gcagcagtgg tcagaacatg 3661ctgaaattcc tttcatggtg ttatttttta tttgttctag ttttgagata aatgagtgac 3721tctgtcataa aatgtccatt tttgatttgt tcttgaagaa ttagggtaca aaacaagtat 3781cgtagtcata gtaacaactg ttactgaaca ggtcttctgt aggggctcct aagtatgaga 3841caacatgcag tggtttctga aatgactgag cgataagtaa attatatatt ctttttttaa 3901aagatttatt ttatttatat gagtacactg tagctgtctt cagacacacc agaagagggc 3961atcagatctt attacagatg gttgtgagcc accatgtggt tgctgggaat tgaactcagg 4021acctttggaa gggcagtcag tgctcttaac tgctgagcta tctctctagc cccaaattat 4081atattcttat acagacccac agtccagaga aagtgaagct ggctcagagt tagcaccaac 4141atttccctga aaaaatgtgt taggtgttta aaaatctcat cgtaaataaa ttattttatt 4201tttagtttaa gtgaatttct cttaatttaa ataagactaa tatttttgtt tgactgaaga 4261cccttgtact ctctggtgtc agtttggtgt cacttgaaac aatgacaacc acgtcagcat 4321gttactgcaa tgtcagtgat ggtttcaaag gagaaaatgg atgtcatctt aggactgctt 4381gtgtgtgtat agaccgtggt ggatgctgta gagtgcttgt tgtctgagtg ttgttttgtg 4441gtatggctgt ctctctgaat aatgtcaacc ttacagaaag agaaggtgtt atatgtgtaa 4501catatggctt tataaaagat ttaatgtcaa aagagtctat aaatattgct gttattttta 4561aaggcacttt actccttggt tttattattc cattttgctg gcgtgtatta gctttatata 4621aatcacaaca cacaaaactc gtccatcttg taatctttgt acttttgcaa tggaaaagtg 4681tgtatactgt gcacagactt ttatatagct gagtgcctag actgggtgga gaggccatga 4741gtagatagca gtaaagtcct ccagctatag gctagccttg tcttcatcat cctgggacag 4801gtgagaacgg tgagcacagg tgagtctgag cttgcacact gaccagaatt cagtcaccct 4861gtaataagta tgtatttaat gagtctgtta gtgtggtagt gtgattttga aaggtttaac 4921taaggaatgg tgaggtcttt gtttataggc aagcctggct taacagtgaa ggggaggggg 4981ctgagggaaa gctttttttt tttttaattt cagaaatgga agcaaaatcc atgtgcaaag 5041agactagcta cttggctttc agagcagagg actcaaagct tgtttgcagt ggttctgaag 5101ttggggtggc actttgtgag tgaggaggac catgtccaca ggcaatccct aagcaagatc 5161gtctcgaaat tgcactgtgt tctttagcag tagtggctgg gtaggggcac acagcggaac 5221acccacttgc agtggctggg gaggcctgag aagcacaggc cagcgggagc tctctcccat 5281gccttcttgt ccctctggac agcccctcct cattccttgt cccagcagag cctggtttgc 5341ccctggggca atagggttgg actgtgtggt gcagatagcc ctcgtgcctg tggattactt 5401taattttgta atcttaggtt ttctgtacgg ttttcccatt gccttttaaa atattttgag 5461tgtccttctc cttatcaaga tggtagtgta gtaggattgt tttactcaca acatggttta 5521ggagccatag ctacaaatag gaaatataag aattctattt ctctactgtg aggcaaatct 5581gtatatatgt atggagagtc aggaggatga acaagggaga ggaaaggggc ccaggcacat 5641ttttaatcca aaagctacaa agtgtcgagc tcctcagggc cagcttcaca gagagtccag 5701ctcagttcac aaagtatttt ctaagttggg gaaatgcatt gagaaacaga gcgagatatc 5761tgtgtagtgc agctgtgggt ggttgctatg cattttatcc tcagagtagc ctggggtttt 5821tattttatgt ttgccaagtg cttaggtaaa tggccgggct cctcttacct ctgacttctg 5881gagcgtgtcc attctctggt tgactgaatg tggcattttc ataaatctag gagcagcagc 5941cctcccaact gcaatttagt aagcaggtag ataagcttgc atctgtttgc atcttcctgc 6001actgagttgg gagtgcaaaa ccccgtactt ggcctggtga gtaactgcca acaagtattt 6061atgggtcatt tgctaggtgg ctagcatacg gcacggggct aatgagacct ggggcctgct 6121ctcatatagc ttactgctca gtttctatac cagagcatcc gttggtgctt cttagcctag 6181gcatgggtga caggcatgtc tggggaccac tttgggagac aacctagtgt aaccttattg 6241caaaggacta agagacaaaa atcctgggtt ctttctccat cacttgctct gtagctgaat 6301gaacaccacc tcgatttctt gagtttcagt gtcttgttct gtctgatgaa agggttggat 6361atgtagttgg ataagcggta caaattgtta gggttccagg ccatgcctga tacatctgag 6421tttttgctgg aggtaggaaa tttcaactca gaagctcatc cacagaaaac agtgaccagc 6481agcaggtatg gagccataag gctggaaggc ttcaaagacc ccttcttctg ttactgttat 6541ccacggcagt tattctgtgt aggtgtgaag gagtggctac tgactctgtg tggatcagcg 6601tttacatatg acctgatggg agtgcatctg gtatgtgttc ctcccccctg tattgctgga 6661gagattggca atcgtaggta tacacggaag tgtcgggatg ttcagtggcg cgcacttgga 6721tgtttctttt cactttattt ctatagaaac aggttccagg agccagagaa gtaggggaaa 6781aaatccctga gctcatctct ctctactact taataatgca aacatttaaa ttcttgggaa 6841gattttcccg ccccactccc tacccccagt cacaggtcag aataggattt ccttcttaga 6901gaaggtaggt catggggcct gcgattaaaa aaacaaaaac ataaaacaaa caaacaaaca 6961aggtggcttt ccttggtctt tgtgattcca gctcttcacc agtgaaggaa ttctttagtt 7021ccatagtgca gcctgggtgg gtggagaaga ggctgttata gtgggagcca gtgagcaaag 7081agggttggag gaggcagagg acagggctca gggaaggcaa gcctgtggct ctgggcattg 7141gccctcttgt caaaggtgtc agagcatggc ttcctgtgag gggctttccc ttgctcctgt 7201gtgagaatct gtgcgttgtc ttactggatg ggggacctgg atggagatgt taggggagat 7261agcttagtct tgttctaaac tctagacttg ctaaaaaggg ttctcttgag tccaaatgca 7321gtgccagagg gtgagaagca gaattggcca gtagtgaaca gtggtattgt gggtgataag 7381ccctttctgg tggccttaaa tagcagtgct agtccttgag tgccacaggg tcccctacct 7441ccgtcctggc agtgctgatg ggtttgtttc agcatatttt ggttctcatt ctcatttagg 7501gaaaagggct gttgatgaag ggattatcct cccaggcacc aggggcctca gcacagttcc 7561ctgtgctttt aaacactgtt gactttcatt agttattcta aagggattta tattggagat 7621acaactccct ttggtttcat attatgaaat agctttgtac tgtggaatgc taactctgga 7681aagtctccct cataccagaa ccaaacattc atttctttta tatatatata tatattatct 7741ccctggtact ctccagggag gtggttatta tcaagctgac ccaaaggagt gcagtatgtg 7801ttctagttcc ttttctggta ccttgttcaa cattcttttt tcctgaagaa catccttttg 7861tttatgaaaa cgtgaatagc atcatgtaaa acaatccctt gctatcagaa tgctccagtt 7921tggccttaat tttgtaaacc ttggagagga gtggagcgcg gctgtgagaa gagatgtacc 7981atgtactctt tctgtatcat taaagtgcag tttttatgct tctSEQ ID NO: 43 Mouse CYLD Isoform 2 Amino Acid Sequence (NP_001121643.1)1 mssglwsqek vtspyweeri fylllqecsv tdkqtqkllk vpkgsigqyi qdrsvghsrv 61pstkgkknqi glkileqpha vlfvdekdvv einekftell laitnceerl slfrnrlrls 121kglqvdvgsp vkvqlrsgee kfpgvvrfrg pllaertvsg iffgvellee grggqftdgv 181yqgkqlfqcd edcgvfvald kleliedddn glesdfagpg dtmqvepppl einsrvslkv 241gestesgtvi fcdvlpgkes lgyfvgvdmd npignwdgrf dgvqlcsfas vestillhin 301diipdsvtqe rrppklafms rgvgdkgsss hnkpkvtgst sdpgsrnrse lfytlngssv 361dsqqsksknp wyidevaedp aksltemssd fghsspppqp psmnslssen rfhslpfslt 421kmpntngsma hsplslsvqs vmgelnstpv qespplpiss gnahglevgs laevkenppf 481ygvirwigqp pglsdvlagl eledecagct dgtfrgtryf tcalkkalfv klkscrpdsr 541faslqpvsng iercnslafg gylsevveen tppkmekegl eimigkkkgi qghynscyld 601stlfclfafs saldtvllrp kekndieyys etqellrtei vnplriygyv catkimklrk 661ilekveaasg ftseekdpee flnilfhdil rvepllkirs agqkvqdcnf yqifmeknek 721vgvptiqqll ewsfinsnlk faeapsclii qmprfgkdfk lfkkifpsle lnitdlledt 781prqcricggl amyecrecyd dpdisagkik qfcktcstqv hlhprrlnhs yhpvslpkdl 841pdwdwrhgci pcqkmelfav lcietshyva fvkygkddsa wlffdsmadr dggqngfnip 901qvtpcpevge ylkmsledlh sldsrriqgc arrllcdaym cmyqsptmsl ykSEQ ID NO: 44 Mouse CYLD transcript variant 2 cDNA sequence(NM_001128171,2; CDS: 357 . . . 3215) 1agttcggagg cggggcaggt gggggcgggc ccaggtagca ggttcggctg cgcgggggcc 61cgcgcgcctg agcagtgagc tcctatgtca tggattctga actggcttat aatatctggc 121atggattcct tttagcagag caggcctcaa atccgataga gcatggttgc ttgatcccat 181tgcagccctg ccactagtgg ctcctggcac tttgaattgc tgtcttttta caacatggat 241gccaggttgc taaaatcttg ctttgggact tacagcgagt tcattttttt ggattttatg 301acagatttac tagtggctcc tttttgccag tcaatgttct gaaagttact gtcacaatga 361gttcaggcct gtggagccaa gagaaagtta cttcacccta ctgggaagaa cggatttttt 421atctgcttct tcaagaatgc agtgtaacag acaaacaaac tcagaagctg ctgaaagtac 481ccaaagggag tataggacag tacatccaag accgttctgt ggggcattca agagttcctt 541ccacaaaagg caagaaaaat cagattggat taaaaatctt ggagcaaccg catgcagttc 601tgtttgttga tgaaaaggat gttgtagaaa taaatgaaaa attcacagag ttactgttgg 661caattaccaa ctgtgaggag aggctcagcc tatttagaaa cagactccga ctaagtaaag 721gcctccaggt agacgtgggc agtcctgtga aagtacagct gcgatctggg gaagagaaat 781ttccaggagt tgtacgcttc agaggacctt tattagcgga gaggacggtg tcggggattt 841tctttggagt agaattattg gaagaaggtc gtggtcaagg tttcacggat ggggtatatc 901aagggaagca gcttttccag tgtgatgagg actgtggcgt gtttgttgca ttggacaaac 961tagaacttat agaagatgat gacaatggat tggaaagtga ttttgcaggc ccaggagata 1021caatgcaggt tgaacctccc cctttggaaa taaactccag agtttctttg aaggttggag 1081aaagtacaga atctggaaca gtaatattct gtgatgtttt accaggaaaa gagagtctag 1141gatattttgt tggtgtggac atggataacc ctattggcaa ctgggatgga aggtttgatg 1201gagtacagct ctgtagtttt gcaagtgttg aaagtacaat tctcctgcac atcaatgaca 1261tcatcccaga tagcgtgaca caggaaagga ggcctcccaa acttgccttt atgtcaagag 1321gtgtaggtga caaaggttca tctagtcata ataaaccaaa ggttacagga tctacctcag 1381accctggaag tagaaacaga tctgaattat tttatacctt aaatgggtca tctgttgact 1441cacaacaatc caagtccaaa aatccatggt acattgatga agttgcagaa gaccctgcaa 1501agtcacttac agagatgtct tcggacttcg gacattcatc tcctccaccg cagcctcctt 1561ccatgaactc cttgtctagc gagaacagat tccactcctt acccttcagc ctgacaaaga 1621tgcccaatac taatggcagc atggctcata gtccactctc tctgtcagtg cagtctgtga 1681tgggggagct gaacagcaca cctgtccagg agagtccacc cttgcccatc tcttctggga 1741atgcacacgg gctagaggtg ggctcactgg ctgaagtaaa agagaacccc ccgttctatg 1801gggttatccg ttggattggc cagccaccag ggctcagtga cgtgctagct ggactggaac 1861tggaagatga atgcgcaggc tgtacagatg gaactttcag gggcacgcgg tatttcacgt 1921gtgccctgaa gaaggcactg tttgtgaaac tgaagagctg cagaccggac tctaggtttg 1981catccttgca gcctgtttcc aatcaaattg aaaggtgtaa ctctttagca tttgggggct 2041atttaagtga agtagtagaa gaaaatactc cacctaaaat ggaaaaggaa ggtttagaga 2101taatgattgg aaagaagaaa ggcatccagg gccattacaa ttcttgttac ttagactcaa 2161ctttattctg cttatttgct tttagttctg ccctggacac tgtgttactt agacccaaag 2221agaagaatga tatagagtat tacagtgaga ctcaggagct actgaggaca gagatagtca 2281atcctctgag aatatatgga tatgtgtgtg ccacaaagat tatgaaactg aggaaaatac 2341ttgaaaaagt tgaggctgca tcaggtttta cctctgaaga aaaagatcct gaagaattct 2401taaatatcct gtttcatgat attttaaggg ttgaaccatt gttaaaaata agatcagcag 2461gtcaaaaagt tcaagactgt aacttctatc aaatttttat ggaaaaaaat gagaaagttg 2521gagtacccac aattcagcag ttattagaat ggtcttttat caacagcaac ctgaaatttg 2581cagaggcacc atcatgcttg attatccaga tgcctcggtt tggaaaagac tttaaactat 2641ttaaaaaaat ttttccttcc ctggaattaa atataacaga tttacttgaa gacactccca 2701ggcagtgccg catctgtgga ggacttgcga tgtacgagtg cagggagtgc tatgacgatc 2761cggacatctc agctgggaag atcaagcagt tctgtaagac ctgcagcact caggttcacc 2821ttcatcccag gaggttgaat cattcttatc atccagtatc acttcccaaa gacttgcctg 2881actgggactg gagacacggc tgcatcccct gtcagaagat ggagttattt gctgttctct 2941gcatagaaac gagccactat gttgcttttg tgaagtatgg gaaggatgac tctgcctggc 3001ttttctttga cagcatggcg gatcgagatg gtggtcagaa tggcttcaac attccacaag 3061tgacgccctg cccagaagtg ggagagtact tgaagatgtc tctggaggac ctgcactctt 3121tggattccag aaggattcaa ggctgtgcgc gcagacttct ttgcgatgca tacatgtgca 3181tgtaccagag tccaaccatg agcctgtaca aataaccagg ttatccgcag tgggcagaga 3241cagcacaaac cttagtgctg tgtcttcctc cagcttgtgg ttctgtccgg cacccattgc 3301cggcaatggg tgtctctttt gatgatggcc cttcagcaaa ggattcctgt gtttccaaac 3361aaattgcttt tgtgttcctg aagtatttaa taagaagcat tttgcactct aggaagtatg 3421tttgtgttga ttttttaaga agtctaaatg gatttattaa tatctgacac tttaagttaa 3481ctgcattgat gatacgatat ttttggaagc atacaatttt aattgtgacg tctaaaacct 3541cttttagtcc attgaggatg taaataaata tttcttctta tggaccaggg atatgaaatc 3601attttccttt tgtagctaat gattgccttg agaaagacat aatatgattt tattaagagt 3661ctgcctttac tccaattgtt gaaggtgtgc tgagtttaat tgttaatttt cctatatagt 3721gctgatttcc tgcatgtctg tactttgctg agtttctgtg ttcctgcagc agtggtcaga 3781acatgctgaa attcctttca tggtgttatt ttttatttgt tctagttttg agataaatga 3841gtgactctgt cataaaatgt ccatttttga tttgttcttg aagaattagg gtacaaaaca 3901agtatcgtag tcatagtaac aactgttact gaacaggtct tctgtagggg ctcctaagta 3961tgagacaaca tgcagtggtt tctgaaatga ctgagcgata agtaaattat atattctttt 4021tttaaaagat ttattttatt tatatgagta cactgtagct gtcttcagac acaccagaag 4081agggcatcag atcttattac agatggttgt gagccaccat gtggttgctg ggaattgaac 4141tcaggacctt tggaagggca gtcagtgctc ttaactgctg agctatctct ctagccccaa 4201attatatatt cttatacaga cccacagtcc agagaaagtg aagctggctc agagttagca 4261ccaacatttc cctgaaaaaa tgtgttaggt gtttaaaaat ctcatcgtaa ataaattatt 4321ttatttttag tttaagtgaa tttctcttaa tttaaataag actaatattt ttgtttgact 4381gaagaccctt gtactctctg gtgtcagttt ggtgtcactt gaaacaatga caaccacgtc 4441agcatgttac tgcaatgtca gtgatggttt caaaggagaa aatggatgtc atcttaggac 4501tgcttgtgtg tgtatagacc gtggtggatg ctgtagagtg cttgttgtct gagtgttgtt 4561ttgtggtatg gctgtctctc tgaataatgt caaccttaca gaaagagaag gtgttatatg 4621tgtaacatat ggctttataa aagatttaat gtcaaaagag tctataaata ttgctgttat 4681ttttaaaggc actttactcc ttggttttat tattccattt tgctggcgtg tattagcttt 4741atataaatca caacacacaa aactcgtcca tcttgtaatc tttgtacttt tgcaatggaa 4801aagtgtgtat actgtgcaca gacttttata tagctgagtg cctagactgg gtggagaggc 4861catgagtaga tagcagtaaa gtcctccagc tataggctag ccttgtcttc atcatcctgg 4921gacaggtgag aacggtgagc acaggtgagt ctgagcttgc acactgacca gaattcagtc 4981accctgtaat aagtatgtat ttaatgagtc tgttagtgtg gtagtgtgat tttgaaaggt 5041ttaactaagg aatggtgagg tctttgttta taggcaagcc tggcttaaca gtgaagggga 5101gggggctgag ggaaagcttt tttttttttt aatttcagaa atggaagcaa aatccatgtg 5161caaagagact agctacttgg ctttcagagc agaggactca aagcttgttt gcagtggttc 5221tgaagttggg gtggcacttt gtgagtgagg aggaccatgt ccacaggcaa tccctaagca 5281agatcgtctc gaaattgcac tgtgttcttt agcagtagtg gctgggtagg ggcacacagc 5341ggaacaccca cttgcagtgg ctggggaggc ctgagaagca caggccagcg ggagctctct 5401cccatgcctt cttgtccctc tggacagccc ctcctcattc cttgtcccag cagagcctgg 5461tttgcccctg gggcaatagg gttggactgt gtggtgcaga tagccctcgt gcctgtggat 5521tactttaatt ttgtaatctt aggttttctg tacggttttc ccattgcctt ttaaaatatt 5581ttgagtgtcc ttctccttat caagatggta gtgtagtagg attgttttac tcacaacatg 5641gtttaggagc catagctaca aataggaaat ataagaattc tatttctcta ctgtgaggca 5701aatctgtata tatgtatgga gagtcaggag gatgaacaag ggagaggaaa ggggcccagg 5761cacattttta atccaaaagc tacaaagtgt cgagctcctc agggccagct tcacagagag 5821tccagctcag ttcacaaagt attttctaag ttggggaaat gcattgagaa acagagcgag 5881atatctgtgt agtgcagctg tgggtggttg ctatgcattt tatcctcaga gtagcctggg 5941gtttttattt tatgtttgcc aagtgcttag gtaaatggcc gggctcctct tacctctgac 6001ttctggagcg tgtccattct ctggttgact gaatgtggca ttttcataaa tctaggagca 6061gcagccctcc caactgcaat ttagtaagca ggtagataag cttgcatctg tttgcatctt 6121cctgcactga gttgggagtg caaaaccccg tacttggcct ggtgagtaac tgccaacaag 6181tatttatggg tcatttgcta ggtggctagc atacggcacg gggctaatga gacctggggc 6241ctgctctcat atagcttact gctcagtttc tataccagag catccgttgg tgcttcttag 6301cctaggcatg ggtgacaggc atgtctgggg accactttgg gagacaacct agtgtaacct 6361tattgcaaag gactaagaga caaaaatcct gggttctttc tccatcactt gctctgtagc 6421tgaatgaaca ccacctcgat ttcttgagtt tcagtgtctt gttctgtctg atgaaagggt 6481tggatatgta gttggataag cggtacaaat tgttagggtt ccaggccatg cctgatacat 6541ctgagttttt gctggaggta ggaaatttca actcagaagc tcatccacag aaaacagtga 6601ccagcagcag gtatggagcc ataaggctgg aaggcttcaa agaccccttc ttctgttact 6661gttatccacg gcagttattc tgtgtaggtg tgaaggagtg gctactgact ctgtgtggat 6721cagcgtttac atatgacctg atgggagtgc atctggtatg tgttcctccc ccctgtattg 6781ctggagagat tggcaatcgt aggtatacac ggaagtgtcg ggatgttcag tggcgcgcac 6841ttggatgttt cttttcactt tatttctata gaaacaggtt ccaggagcca gagaagtagg 6901ggaaaaaatc cctgagctca tctctctcta ctacttaata atgcaaacat ttaaattctt 6961gggaagattt tcccgcccca ctccctaccc ccagtcacag gtcagaatag gatttccttc 7021ttagagaagg taggtcatgg ggcctgcgat taaaaaaaca aaaacataaa acaaacaaac 7081aaacaaggtg gctttccttg gtctttgtga ttccagctct tcaccagtga aggaattctt 7141tagttccata gtgcagcctg ggtgggtgga gaagaggctg ttatagtggg agccagtgag 7201caaagagggt tggaggaggc agaggacagg gctcagggaa ggcaagcctg tggctctggg 7261cattggccct cttgtcaaag gtgtcagagc atggcttcct gtgaggggct ttcccttgct 7321cctgtgtgag aatctgtgcg ttgtcttact ggatggggga cctggatgga gatgttaggg 7381gagatagctt agtcttgttc taaactctag acttgctaaa aagggttctc ttgagtccaa 7441atgcagtgcc agagggtgag aagcagaatt ggccagtagt gaacagtggt attgtgggtg 7501ataagccctt tctggtggcc ttaaatagca gtgctagtcc ttgagtgcca cagggtcccc 7561tacctccgtc ctggcagtgc tgatgggttt gtttcagcat attttggttc tcattctcat 7621ttagggaaaa gggctgttga tgaagggatt atcctcccag gcaccagggg cctcagcaca 7681gttccctgtg cttttaaaca ctgttgactt tcattagtta ttctaaaggg atttatattg 7741gagatacaac tccctttggt ttcatattat gaaatagctt tgtactgtgg aatgctaact 7801ctggaaagtc tccctcatac cagaaccaaa cattcatttc ttttatatat atatatatat 7861tatctccctg gtactctcca gggaggtggt tattatcaag ctgacccaaa ggagtgcagt 7921atgtgttcta gttccttttc tggtaccttg ttcaacattc ttttttcctg aagaacatcc 7981ttttgtttat gaaaacgtga atagcatcat gtaaaacaat cccttgctat cagaatgctc 8041cagtttggcc ttaattttgt aaaccttgga gaggagtgga gcgcggctgt gagaagagat 8101gtaccatgta ctctttctgt atcattaaag tgcagttttt atgcttctSEQ ID NO: 45 Mouse CYLD transcript variant 3 cDNA sequence (NM_173369.3;CDS: 223 . . . 3081) 1agttcggagg cggggcaggt gggggcgggc ccaggtagca ggttcggctg cgcgggggcc 61cgcgcgcctg aggcactttg aattgctgtc tttttacaac atggatgcca ggttgctaaa 121atcttgcttt gggacttaca gcgagttcat ttttttggat tttatgacag atttactagt 181ggctcctttt tgccagtcaa tgttctgaaa gttactgtca caatgagttc aggcctgtgg 241agccaagaga aagttacttc accctactgg gaagaacgga ttttttatct gcttcttcaa 301gaatgcagtg taacagacaa acaaactcag aagctgctga aagtacccaa agggagtata 361ggacagtaca tccaagaccg ttctgtgggg cattcaagag ttccttccac aaaaggcaag 421aaaaatcaga ttggattaaa aatcttggag caaccgcatg cagttctgtt tgttgatgaa 481aaggatgttg tagaaataaa tgaaaaattc acagagttac tgttggcaat taccaactgt 541gaggagaggc tcagcctatt tagaaacaga ctccgactaa gtaaaggcct ccaggtagac 601gtgggcagtc ctgtgaaagt acagctgcga tctggggaag agaaatttcc aggagttgta 661cgcttcagag gacctttatt agcggagagg acggtgtcgg ggattttctt tggagtagaa 721ttattggaag aaggtcgtgg tcaaggtttc acggatgggg tatatcaagg gaagcagctt 781ttccagtgtg atgaggactg tggcgtgttt gttgcattgg acaaactaga acttatagaa 841gatgatgaca atggattgga aagtgatttt gcaggcccag gagatacaat gcaggttgaa 901cctccccctt tggaaataaa ctccagagtt tctttgaagg ttggagaaag tacagaatct 961ggaacagtaa tattctgtga tgttttacca ggaaaagaga gtctaggata ttttgttggt 1021gtggacatgg ataaccctat tggcaactgg gatggaaggt ttgatggagt acagctctgt 1081agttttgcaa gtgttgaaag tacaattctc ctgcacatca atgacatcat cccagatagc 1141gtgacacagg aaaggaggcc tcccaaactt gcctttatgt caagaggtgt aggtgacaaa 1201ggttcatcta gtcataataa accaaaggtt acaggatcta cctcagaccc tggaagtaga 1261aacagatctg aattatttta taccttaaat gggtcatctg ttgactcaca acaatccaag 1321tccaaaaatc catggtacat tgatgaagtt gcagaagacc ctgcaaagtc acttacagag 1381atgtcttcgg acttcggaca ttcatctcct ccaccgcagc ctccttccat gaactccttg 1441tctagcgaga acagattcca ctccttaccc ttcagcctga caaagatgcc caatactaat 1501ggcagcatgg ctcatagtcc actctctctg tcagtgcagt ctgtgatggg ggagctgaac 1561agcacacctg tccaggagag tccacccttg cccatctctt ctgggaatgc acacgggcta 1621gaggtgggct cactggctga agtaaaagag aaccccccgt tctatggggt tatccgttgg 1681attggccagc caccagggct cagtgacgtg ctagctggac tggaactgga agatgaatgc 1741gcaggctgta cagatggaac tttcaggggc acgcggtatt tcacgtgtgc cctgaagaag 1801gcactgtttg tgaaactgaa gagctgcaga ccggactcta ggtttgcatc cttgcagcct 1861gtttccaatc aaattgaaag gtgtaactct ttagcatttg ggggctattt aagtgaagta 1921gtagaagaaa atactccacc taaaatggaa aaggaaggtt tagagataat gattggaaag 1981aagaaaggca tccagggcca ttacaattct tgttacttag actcaacttt attctgctta 2041tttgctttta gttctgccct ggacactgtg ttacttagac ccaaagagaa gaatgatata 2101gagtattaca gtgagactca ggagctactg aggacagaga tagtcaatcc tctgagaata 2161tatggatatg tgtgtgccac aaagattatg aaactgagga aaatacttga aaaagttgag 2221gctgcatcag gttttacctc tgaagaaaaa gatcctgaag aattcttaaa tatcctgttt 2281catgatattt taagggttga accattgtta aaaataagat cagcaggtca aaaagttcaa 2341gactgtaact tctatcaaat ttttatggaa aaaaatgaga aagttggagt acccacaatt 2401cagcagttat tagaatggtc ttttatcaac agcaacctga aatttgcaga ggcaccatca 2461tgcttgatta tccagatgcc tcggtttgga aaagacttta aactatttaa aaaaattttt 2521ccttccctgg aattaaatat aacagattta cttgaagaca ctcccaggca gtgccgcatc 2581tgtggaggac ttgcgatgta cgagtgcagg gagtgctatg acgatccgga catctcagct 2641gggaagatca agcagttctg taagacctgc agcactcagg ttcaccttca tcccaggagg 2701ttgaatcatt cttatcatcc agtatcactt cccaaagact tgcctgactg ggactggaga 2761cacggctgca tcccctgtca gaagatggag ttatttgctg ttctctgcat agaaacgagc 2821cactatgttg cttttgtgaa gtatgggaag gatgactctg cctggctttt ctttgacagc 2881atggcggatc gagatggtgg tcagaatggc ttcaacattc cacaagtgac gccctgccca 2941gaagtgggag agtacttgaa gatgtctctg gaggacctgc actctttgga ttccagaagg 3001attcaaggct gtgcgcgcag acttctttgc gatgcataca tgtgcatgta ccagagtcca 3061accatgagcc tgtacaaata accaggttat ccgcagtggg cagagacagc acaaacctta 3121gtgctgtgtc ttcctccagc ttgtggttct gtccggcacc cattgccggc aatgggtgtc 3181tcttttgatg atggcccttc agcaaaggat tcctgtgttt ccaaacaaat tgcttttgtg 3241ttcctgaagt atttaataag aagcattttg cactctagga agtatgtttg tgttgatttt 3301ttaagaagtc taaatggatt tattaatatc tgacacttta agttaactgc attgatgata 3361cgatattttt ggaagcatac aattttaatt gtgacgtcta aaacctcttt tagtccattg 3421aggatgtaaa taaatatttc ttcttatgga ccagggatat gaaatcattt tccttttgta 3481gctaatgatt gccttgagaa agacataata tgattttatt aagagtctgc ctttactcca 3541attgttgaag gtgtgctgag tttaattgtt aattttccta tatagtgctg atttcctgca 3601tgtctgtact ttgctgagtt tctgtgttcc tgcagcagtg gtcagaacat gctgaaattc 3661ctttcatggt gttatttttt atttgttcta gttttgagat aaatgagtga ctctgtcata 3721aaatgtccat ttttgatttg ttcttgaaga attagggtac aaaacaagta tcgtagtcat 3781agtaacaact gttactgaac aggtcttctg taggggctcc taagtatgag acaacatgca 3841gtggtttctg aaatgactga gcgataagta aattatatat tcttttttta aaagatttat 3901tttatttata tgagtacact gtagctgtct tcagacacac cagaagaggg catcagatct 3961tattacagat ggttgtgagc caccatgtgg ttgctgggaa ttgaactcag gacctttgga 4021agggcagtca gtgctcttaa ctgctgagct atctctctag ccccaaatta tatattctta 4081tacagaccca cagtccagag aaagtgaagc tggctcagag ttagcaccaa catttccctg 4141aaaaaatgtg ttaggtgttt aaaaatctca tcgtaaataa attattttat ttttagttta 4201agtgaatttc tcttaattta aataagacta atatttttgt ttgactgaag acccttgtac 4261tctctggtgt cagtttggtg tcacttgaaa caatgacaac cacgtcagca tgttactgca 4321atgtcagtga tggtttcaaa ggagaaaatg gatgtcatct taggactgct tgtgtgtgta 4381tagaccgtgg tggatgctgt agagtgcttg ttgtctgagt gttgttttgt ggtatggctg 4441tctctctgaa taatgtcaac cttacagaaa gagaaggtgt tatatgtgta acatatggct 4501ttataaaaga tttaatgtca aaagagtcta taaatattgc tgttattttt aaaggcactt 4561tactccttgg ttttattatt ccattttgct ggcgtgtatt agctttatat aaatcacaac 4621acacaaaact cgtccatctt gtaatctttg tacttttgca atggaaaagt gtgtatactg 4681tgcacagact tttatatagc tgagtgccta gactgggtgg agaggccatg agtagatagc 4741agtaaagtcc tccagctata ggctagcctt gtcttcatca tcctgggaca ggtgagaacg 4801gtgagcacag gtgagtctga gcttgcacac tgaccagaat tcagtcaccc tgtaataagt 4861atgtatttaa tgagtctgtt agtgtggtag tgtgattttg aaaggtttaa ctaaggaatg 4921gtgaggtctt tgtttatagg caagcctggc ttaacagtga aggggagggg gctgagggaa 4981agcttttttt ttttttaatt tcagaaatgg aagcaaaatc catgtgcaaa gagactagct 5041acttggcttt cagagcagag gactcaaagc ttgtttgcag tggttctgaa gttggggtgg 5101cactttgtga gtgaggagga ccatgtccac aggcaatccc taagcaagat cgtctcgaaa 5161ttgcactgtg ttctttagca gtagtggctg ggtaggggca cacagcggaa cacccacttg 5221cagtggctgg ggaggcctga gaagcacagg ccagcgggag ctctctccca tgccttcttg 5281tccctctgga cagcccctcc tcattccttg tcccagcaga gcctggtttg cccctggggc 5341aatagggttg gactgtgtgg tgcagatagc cctcgtgcct gtggattact ttaattttgt 5401aatcttaggt tttctgtacg gttttcccat tgccttttaa aatattttga gtgtccttct 5461ccttatcaag atggtagtgt agtaggattg ttttactcac aacatggttt aggagccata 5521gctacaaata ggaaatataa gaattctatt tctctactgt gaggcaaatc tgtatatatg 5581tatggagagt caggaggatg aacaagggag aggaaagggg cccaggcaca tttttaatcc 5641aaaagctaca aagtgtcgag ctcctcaggg ccagcttcac agagagtcca gctcagttca 5701caaagtattt tctaagttgg ggaaatgcat tgagaaacag agcgagatat ctgtgtagtg 5761cagctgtggg tggttgctat gcattttatc ctcagagtag cctggggttt ttattttatg 5821tttgccaagt gcttaggtaa atggccgggc tcctcttacc tctgacttct ggagcgtgtc 5881cattctctgg ttgactgaat gtggcatttt cataaatcta ggagcagcag ccctcccaac 5941tgcaatttag taagcaggta gataagcttg catctgtttg catcttcctg cactgagttg 6001ggagtgcaaa accccgtact tggcctggtg agtaactgcc aacaagtatt tatgggtcat 6061ttgctaggtg gctagcatac ggcacggggc taatgagacc tggggcctgc tctcatatag 6121cttactgctc agtttctata ccagagcatc cgttggtgct tcttagccta ggcatgggtg 6181acaggcatgt ctggggacca ctttgggaga caacctagtg taaccttatt gcaaaggact 6241aagagacaaa aatcctgggt tctttctcca tcacttgctc tgtagctgaa tgaacaccac 6301ctcgatttct tgagtttcag tgtcttgttc tgtctgatga aagggttgga tatgtagttg 6361gataagcggt acaaattgtt agggttccag gccatgcctg atacatctga gtttttgctg 6421gaggtaggaa atttcaactc agaagctcat ccacagaaaa cagtgaccag cagcaggtat 6481ggagccataa ggctggaagg cttcaaagac cccttcttct gttactgtta tccacggcag 6541ttattctgtg taggtgtgaa ggagtggcta ctgactctgt gtggatcagc gtttacatat 6601gacctgatgg gagtgcatct ggtatgtgtt cctcccccct gtattgctgg agagattggc 6661aatcgtaggt atacacggaa gtgtcgggat gttcagtggc gcgcacttgg atgtttcttt 6721tcactttatt tctatagaaa caggttccag gagccagaga agtaggggaa aaaatccctg 6781agctcatctc tctctactac ttaataatgc aaacatttaa attcttggga agattttccc 6841gccccactcc ctacccccag tcacaggtca gaataggatt tccttcttag agaaggtagg 6901tcatggggcc tgcgattaaa aaaacaaaaa cataaaacaa acaaacaaac aaggtggctt 6961tccttggtct ttgtgattcc agctcttcac cagtgaagga attctttagt tccatagtgc 7021agcctgggtg ggtggagaag aggctgttat agtgggagcc agtgagcaaa gagggttgga 7081ggaggcagag gacagggctc agggaaggca agcctgtggc tctgggcatt ggccctcttg 7141tcaaaggtgt cagagcatgg cttcctgtga ggggctttcc cttgctcctg tgtgagaatc 7201tgtgcgttgt cttactggat gggggacctg gatggagatg ttaggggaga tagcttagtc 7261ttgttctaaa ctctagactt gctaaaaagg gttctcttga gtccaaatgc agtgccagag 7321ggtgagaagc agaattggcc agtagtgaac agtggtattg tgggtgataa gccctttctg 7381gtggccttaa atagcagtgc tagtccttga gtgccacagg gtcccctacc tccgtcctgg 7441cagtgctgat gggtttgttt cagcatattt tggttctcat tctcatttag ggaaaagggc 7501tgttgatgaa gggattatcc tcccaggcac caggggcctc agcacagttc cctgtgcttt 7561taaacactgt tgactttcat tagttattct aaagggattt atattggaga tacaactccc 7621tttggtttca tattatgaaa tagctttgta ctgtggaatg ctaactctgg aaagtctccc 7681tcataccaga accaaacatt catttctttt atatatatat atatattatc tccctggtac 7741tctccaggga ggtggttatt atcaagctga cccaaaggag tgcagtatgt gttctagttc 7801cttttctggt accttgttca acattctttt ttcctgaaga acatcctttt gtttatgaaa 7861acgtgaatag catcatgtaa aacaatccct tgctatcaga atgctccagt ttggccttaa 7921ttttgtaaac cttggagagg agtggagcgc ggctgtgaga agagatgtac catgtactct 7981ttctgtatca ttaaagtgca gtttttatgc ttctSEQ ID NO: 46 Mouse CYLD Isoform 3 Amino Acid Sequence (NP_001263208.1)1 mssglwsqek vtspyweeri fylllqecsv tdkqtqkllk vpkgsigqyi qdrsvghsrv 61pstkgkknqi glkileqpha vlfvdekdvv einekftell laitnceerl slfrnrlrls 121kglqvdvgsp vkvqlrsgee kfpgvvrfrg pllaertvsg iffgvellee grgqgftdgv 181yqgkqlfqcd edcgvfvald kleliedddn glesdfagpg dtmqvepppl einsrvslkv 241gestesgtvi fcdvlpgkes lgyfvgvdmd npignwdgrf dgvqlcsfas vestillhin 301diipdsvtqe rrppklafms rgvgdkgsss hnkpkvtgst sdpgsrnrse lfytlngssv 361dsqqsksknp wyideafggy lsevveentp pkmekeglei migkkkgiqg hynscyldst 421lfclfafssa ldtvllrpke kndieyyset qellrteivn plriygyvca tkimklrkil 481ekveaasgft seekdpeefl nilfhdilrv epllkirsag qkvqdcnfyq ifmeknekvg 541vptiqqllew sfinsnlkfa eapscliiqm prfgkdfklf kkifpsleln itdlledtpr 601qcricgglam yecrecyddp disagkikqf cktcstqvhl hprrlnhsyh pvslpkdlpd 661wdwrhgcipc qkmelfavlc ietshyvafv kygkddsawl ffdsmadrdg gqngfnipqv 721tpcpevgeyl kmsledlhsl dsrriqgcar rllcdaymcm yqsptmslykSEQ ID NO: 47 Mouse CYLD transcript variant 4 cDNA sequence(NM_001276279,1; CDS: 354 . . . 2666) 1agttcggagg cggggcaggt gggggcgggc ccaggtagca ggttcggctg cgcgggggcc 61cgcgcgcctg agtgagctcc tatgtcatgg attctgaact ggcttataat atctggcatg 121gattcctttt agcagagcag gcctcaaatc cgatagagca tggttgcttg atcccattgc 181agccctgcca ctagtggctc ctggcacttt gaattgctgt ctttttacaa catggatgcc 241aggttgctaa aatcttgctt tgggacttac agcgagttca tttttttgga ttttatgaca 301gatttactag tggctccttt ttgccagtca atgttctgaa agttactgtc acaatgagtt 361caggcctgtg gagccaagag aaagttactt caccctactg ggaagaacgg attttttatc 421tgcttcttca agaatgcagt gtaacagaca aacaaactca gaagctgctg aaagtaccca 481aagggagtat aggacagtac atccaagacc gttctgtggg gcattcaaga gttccttcca 541caaaaggcaa gaaaaatcag attggattaa aaatcttgga gcaaccgcat gcagttctgt 601ttgttgatga aaaggatgtt gtagaaataa atgaaaaatt cacagagtta ctgttggcaa 661ttaccaactg tgaggagagg ctcagcctat ttagaaacag actccgacta agtaaaggcc 721tccaggtaga cgtgggcagt cctgtgaaag tacagctgcg atctggggaa gagaaatttc 781caggagttgt acgcttcaga ggacctttat tagcggagag gacggtgtcg gggattttct 841ttggagtaga attattggaa gaaggtcgtg gtcaaggttt cacggatggg gtatatcaag 901ggaagcagct tttccagtgt gatgaggact gtggcgtgtt tgttgcattg gacaaactag 961aacttataga agatgatgac aatggattgg aaagtgattt tgcaggccca ggagatacaa 1021tgcaggttga acctccccct ttggaaataa actccagagt ttctttgaag gttggagaaa 1081gtacagaatc tggaacagta atattctgtg atgttttacc aggaaaagag agtctaggat 1141attttgttgg tgtggacatg gataacccta ttggcaactg ggatggaagg tttgatggag 1201tacagctctg tagttttgca agtgttgaaa gtacaattct cctgcacatc aatgacatca 1261tcccagatag cgtgacacag gaaaggaggc ctcccaaact tgcctttatg tcaagaggtg 1321taggtgacaa aggttcatct agtcataata aaccaaaggt tacaggatct acctcagacc 1381ctggaagtag aaacagatct gaattatttt ataccttaaa tgggtcatct gttgactcac 1441aacaatccaa gtccaaaaat ccatggtaca ttgatgaagc atttgggggc tatttaagtg 1501aagtagtaga agaaaatact ccacctaaaa tggaaaagga aggtttagag ataatgattg 1561gaaagaagaa aggcatccag ggccattaca attcttgtta cttagactca actttattct 1621gcttatttgc ttttagttct gccctggaca ctgtgttact tagacccaaa gagaagaatg 1681atatagagta ttacagtgag actcaggagc tactgaggac agagatagtc aatcctctga 1741gaatatatgg atatgtgtgt gccacaaaga ttatgaaact gaggaaaata cttgaaaaag 1801ttgaggctgc atcaggtttt acctctgaag aaaaagatcc tgaagaattc ttaaatatcc 1861tgtttcatga tattttaagg gttgaaccat tgttaaaaat aagatcagca ggtcaaaaag 1921ttcaagactg taacttctat caaattttta tggaaaaaaa tgagaaagtt ggagtaccca 1981caattcagca gttattagaa tggtctttta tcaacagcaa cctgaaattt gcagaggcac 2041catcatgctt gattatccag atgcctcggt ttggaaaaga ctttaaacta tttaaaaaaa 2101tttttccttc cctggaatta aatataacag atttacttga agacactccc aggcagtgcc 2161gcatctgtgg aggacttgcg atgtacgagt gcagggagtg ctatgacgat ccggacatct 2221cagctgggaa gatcaagcag ttctgtaaga cctgcagcac tcaggttcac cttcatccca 2281ggaggttgaa tcattcttat catccagtat cacttcccaa agacttgcct gactgggact 2341ggagacacgg ctgcatcccc tgtcagaaga tggagttatt tgctgttctc tgcatagaaa 2401cgagccacta tgttgctttt gtgaagtatg ggaaggatga ctctgcctgg cttttctttg 2461acagcatggc ggatcgagat ggtggtcaga atggcttcaa cattccacaa gtgacgccct 2521gcccagaagt gggagagtac ttgaagatgt ctctggagga cctgcactct ttggattcca 2581gaaggattca aggctgtgcg cgcagacttc tttgcgatgc atacatgtgc atgtaccaga 2641gtccaaccat gagcctgtac aaataaccag gttatccgca gtgggcagag acagcacaaa 2701ccttagtgct gtgtcttcct ccagcttgtg gttctgtccg gcacccattg ccggcaatgg 2761gtgtctcttt tgatgatggc ccttcagcaa aggattcctg tgtttccaaa caaattgctt 2821ttgtgttcct gaagtattta ataagaagca ttttgcactc taggaagtat gtttgtgttg 2881attttttaag aagtctaaat ggatttatta atatctgaca ctttaagtta actgcattga 2941tgatacgata tttttggaag catacaattt taattgtgac gtctaaaacc tcttttagtc 3001cattgaggat gtaaataaat atttcttctt atggaccagg gatatgaaat cattttcctt 3061ttgtagctaa tgattgcctt gagaaagaca taatatgatt ttattaagag tctgccttta 3121ctccaattgt tgaaggtgtg ctgagtttaa ttgttaattt tcctatatag tgctgatttc 3181ctgcatgtct gtactttgct gagtttctgt gttcctgcag cagtggtcag aacatgctga 3241aattcctttc atggtgttat tttttatttg ttctagtttt gagataaatg agtgactctg 3301tcataaaatg tccatttttg atttgttctt gaagaattag ggtacaaaac aagtatcgta 3361gtcatagtaa caactgttac tgaacaggtc ttctgtaggg gctcctaagt atgagacaac 3421atgcagtggt ttctgaaatg actgagcgat aagtaaatta tatattcttt ttttaaaaga 3481tttattttat ttatatgagt acactgtagc tgtcttcaga cacaccagaa gagggcatca 3541gatcttatta cagatggttg tgagccacca tgtggttgct gggaattgaa ctcaggacct 3601ttggaagggc agtcagtgct cttaactgct gagctatctc tctagcccca aattatatat 3661tcttatacag acccacagtc cagagaaagt gaagctggct cagagttagc accaacattt 3721ccctgaaaaa atgtgttagg tgtttaaaaa tctcatcgta aataaattat tttattttta 3781gtttaagtga atttctctta atttaaataa gactaatatt tttgtttgac tgaagaccct 3841tgtactctct ggtgtcagtt tggtgtcact tgaaacaatg acaaccacgt cagcatgtta 3901ctgcaatgtc agtgatggtt tcaaaggaga aaatggatgt catcttagga ctgcttgtgt 3961gtgtatagac cgtggtggat gctgtagagt gcttgttgtc tgagtgttgt tttgtggtat 4021ggctgtctct ctgaataatg tcaaccttac agaaagagaa ggtgttatat gtgtaacata 4081tggctttata aaagatttaa tgtcaaaaga gtctataaat attgctgtta tttttaaagg 4141cactttactc cttggtttta ttattccatt ttgctggcgt gtattagctt tatataaatc 4201acaacacaca aaactcgtcc atcttgtaat ctttgtactt ttgcaatgga aaagtgtgta 4261tactgtgcac agacttttat atagctgagt gcctagactg ggtggagagg ccatgagtag 4321atagcagtaa agtcctccag ctataggcta gccttgtctt catcatcctg ggacaggtga 4381gaacggtgag cacaggtgag tctgagcttg cacactgacc agaattcagt caccctgtaa 4441taagtatgta tttaatgagt ctgttagtgt ggtagtgtga ttttgaaagg tttaactaag 4501gaatggtgag gtctttgttt ataggcaagc ctggcttaac agtgaagggg agggggctga 4561gggaaagctt tttttttttt taatttcaga aatggaagca aaatccatgt gcaaagagac 4621tagctacttg gctttcagag cagaggactc aaagcttgtt tgcagtggtt ctgaagttgg 4681ggtggcactt tgtgagtgag gaggaccatg tccacaggca atccctaagc aagatcgtct 4741cgaaattgca ctgtgttctt tagcagtagt ggctgggtag gggcacacag cggaacaccc 4801acttgcagtg gctggggagg cctgagaagc acaggccagc gggagctctc tcccatgcct 4861tcttgtccct ctggacagcc cctcctcatt ccttgtccca gcagagcctg gtttgcccct 4921ggggcaatag ggttggactg tgtggtgcag atagccctcg tgcctgtgga ttactttaat 4981tttgtaatct taggttttct gtacggtttt cccattgcct tttaaaatat tttgagtgtc 5041cttctcctta tcaagatggt agtgtagtag gattgtttta ctcacaacat ggtttaggag 5101ccatagctac aaataggaaa tataagaatt ctatttctct actgtgaggc aaatctgtat 5161atatgtatgg agagtcagga ggatgaacaa gggagaggaa aggggcccag gcacattttt 5221aatccaaaag ctacaaagtg tcgagctcct cagggccagc ttcacagaga gtccagctca 5281gttcacaaag tattttctaa gttggggaaa tgcattgaga aacagagcga gatatctgtg 5341tagtgcagct gtgggtggtt gctatgcatt ttatcctcag agtagcctgg ggtttttatt 5401ttatgtttgc caagtgctta ggtaaatggc cgggctcctc ttacctctga cttctggagc 5461gtgtccattc tctggttgac tgaatgtggc attttcataa atctaggagc agcagccctc 5521ccaactgcaa tttagtaagc aggtagataa gcttgcatct gtttgcatct tcctgcactg 5581agttgggagt gcaaaacccc gtacttggcc tggtgagtaa ctgccaacaa gtatttatgg 5641gtcatttgct aggtggctag catacggcac ggggctaatg agacctgggg cctgctctca 5701tatagcttac tgctcagttt ctataccaga gcatccgttg gtgcttctta gcctaggcat 5761gggtgacagg catgtctggg gaccactttg ggagacaacc tagtgtaacc ttattgcaaa 5821ggactaagag acaaaaatcc tgggttcttt ctccatcact tgctctgtag ctgaatgaac 5881accacctcga tttcttgagt ttcagtgtct tgttctgtct gatgaaaggg ttggatatgt 5941agttggataa gcggtacaaa ttgttagggt tccaggccat gcctgataca tctgagtttt 6001tgctggaggt aggaaatttc aactcagaag ctcatccaca gaaaacagtg accagcagca 6061ggtatggagc cataaggctg gaaggcttca aagacccctt cttctgttac tgttatccac 6121ggcagttatt ctgtgtaggt gtgaaggagt ggctactgac tctgtgtgga tcagcgttta 6181catatgacct gatgggagtg catctggtat gtgttcctcc cccctgtatt gctggagaga 6241ttggcaatcg taggtataca cggaagtgtc gggatgttca gtggcgcgca cttggatgtt 6301tcttttcact ttatttctat agaaacaggt tccaggagcc agagaagtag gggaaaaaat 6361ccctgagctc atctctctct actacttaat aatgcaaaca tttaaattct tgggaagatt 6421ttcccgcccc actccctacc cccagtcaca ggtcagaata ggatttcctt cttagagaag 6481gtaggtcatg gggcctgcga ttaaaaaaac aaaaacataa aacaaacaaa caaacaaggt 6541ggctttcctt ggtctttgtg attccagctc ttcaccagtg aaggaattct ttagttccat 6601agtgcagcct gggtgggtgg agaagaggct gttatagtgg gagccagtga gcaaagaggg 6661ttggaggagg cagaggacag ggctcaggga aggcaagcct gtggctctgg gcattggccc 6721tcttgtcaaa ggtgtcagag catggcttcc tgtgaggggc tttcccttgc tcctgtgtga 6781gaatctgtgc gttgtcttac tggatggggg acctggatgg agatgttagg ggagatagct 6841tagtcttgtt ctaaactcta gacttgctaa aaagggttct cttgagtcca aatgcagtgc 6901cagagggtga gaagcagaat tggccagtag tgaacagtgg tattgtgggt gataagccct 6961ttctggtggc cttaaatagc agtgctagtc cttgagtgcc acagggtccc ctacctccgt 7021cctggcagtg ctgatgggtt tgtttcagca tattttggtt ctcattctca tttagggaaa 7081agggctgttg atgaagggat tatcctccca ggcaccaggg gcctcagcac agttccctgt 7141gcttttaaac actgttgact ttcattagtt attctaaagg gatttatatt ggagatacaa 7381agttcctttt tttcatatta tgaaatagct ttgtactgtg gaatgctaac tctggaaagt 7261ctccctcata ccagaaccaa acattcattt cttttatata tatatatata ttatctccct 7321ggtactctcc agggaggtgg ttattatcaa gctgacccaa aggagtgcag tatgtgttct 7381agttcctttt ctggtacctt gttcaacatt cttttttcct gaagaacatc cttttgttta 7441tgaaaacgtg aatagcatca tgtaaaacaa tcccttgcta tcagaatgct ccagtttggc 7501cttaattttg taaaccttgg agaggagtgg agcgcggctg tgagaagaga tgtaccatgt 7561actctttctg tatcattaaa gtgcagtttt tatgcttct

TABLE 1B ARSEQ ID NO: 48 Human AR Isoform 1 Amino Acid Sequence (NP_000035.2) 1mevqlglgrv yprppsktyr gafqnlfqsv reviqnpgpr hpeaasaapp gasllllqqq 61qqqqqqqqqq qqqqqqqqqq etsprqqqqq qgedgspqah rrgptgylvl deeqqpsqpq 121salechperg cvpepgaava askglpqqlp appdeddsaa pstlsllgpt fpglsscsad 181lkdilseast mqllqqqqqe avsegsssgr areasgapts skdnylggts tisdnakelc 241kavsvsmglg vealehlspg eqlrgdcmya pllgvppavr ptpcaplaec kgsllddsag 301kstedtaeys pfkggytkgl egeslgcsgs aaagssgtle lpstlslyks galdeaaayq 361srdyynfpla lagppppppp phpharikle npldygsawa aaaaqcrygd laslhgagaa 421gpgsgspsaa assswhtlft aeegqlygpc gggggggggg gggggggggg gggeagavap 481ygytrppqgl agqesdftap dvwypggmvs rvpypsptcv ksemgpwmds ysgpygdmrl 541etardhvlpi dyyfppqktc licgdeasgc hygaltcgsc kvffkraaeg kqkylcasrn 601dctidkfrrk ncpscrlrkc yeagmtlgar klkklgnlkl qeegeasstt spteettqkl 661tvshiegyec qpiflnvlea iepgvvcagh dnnqpdsfaa llsslnelge rqlvhvvkwa 721kalpgfrnlh vddqmaviqy swmglmvfam gwrsftnvns rmlyfapdlv fneyrmhksr 781mysqcvrmrh lsqefgwlqi tpqeflcmka lllfsiipvd glknqkffde lrmnyikeld 841riiackrknp tscsrrfyql tklldsvqpi arelhqftfd llikshmvsv dfpemmaeii 901svqvpkilsg kvkpiyfhtqSEQ ID NO: 49 Human AR transcript variant 1 cDNA sequence (NM_000044.6;CDS; 1127 . . . 3889 1agcgccccct ccgagatccc ggggagccag cttgctggga gagcgggacg gtccggagca 61agcccagagg cagaggaggc gacagaggga aaaagggccg agctagccgc tccagtgctg 121tacaggagcc gaagggacgc accacgccag ccccagcccg gctccagcga cagccaacgc 181ctcttgcagc gcggcggctt cgaagccgcc gcccggagct gccctttcct cttcggtgaa 241gtttttaaaa gctgctaaag actcggagga agcaaggaaa gtgcctggta ggactgacgg 301ctgcctttgt cctcctcctc tccaccccgc ctccccccac cctgccttcc ccccctcccc 361cgtcttctct cccgcagctg cctcagtcgg ctactctcag ccaacccccc tcaccaccct 421tctccccacc cgcccccccg cccccgtcgg cccagcgctg ccagcccgag tttgcagaga 481ggtaactccc tttggctgcg agcgggcgag ctagctgcac attgcaaaga aggctcttag 541gagccaggcg actggggagc ggcttcagca ctgcagccac gacccgcctg gttaggctgc 601acgcggagag aaccctctgt tttcccccac tctctctcca cctcctcctg ccttccccac 661cccgagtgcg gagccagaga tcaaaagatg aaaaggcagt caggtcttca gtagccaaaa 721aacaaaacaa acaaaaacaa aaaagccgaa ataaaagaaa aagataataa ctcagttctt 781atttgcacct acttcagtgg acactgaatt tggaaggtgg aggattttgt ttttttcttt 841taagatctgg gcatcttttg aatctaccct tcaagtatta agagacagac tgtgagccta 901gcagggcaga tcttgtccac cgtgtgtctt cttctgcacg agactttgag gctgtcagag 961cgctttttgc gtggttgctc ccgcaagttt ccttctctgg agcttcccgc aggtgggcag 1021ctagctgcag cgactaccgc atcatcacag cctgttgaac tcttctgagc aagagaaggg 1081gaggcggggt aagggaagta ggtggaagat tcagccaagc tcaaggatgg aagtgcagtt 1141agggctggga agggtctacc ctcggccgcc gtccaagacc taccgaggag ctttccagaa 1201tctgttccag agcgtgcgcg aagtgatcca gaacccgggc cccaggcacc cagaggccgc 1261gagcgcagca cctcccggcg ccagtttgct gctgctgcag cagcagcagc agcagcagca 1321gcagcagcag cagcagcagc agcagcagca gcagcagcag cagcaagaga ctagccccag 1381gcagcagcag cagcagcagg gtgaggatgg ttctccccaa gcccatcgta gaggccccac 1441aggctacctg gtcctggatg aggaacagca accttcacag ccgcagtcgg ccctggagtg 1501ccaccccgag agaggttgcg tcccagagcc tggagccgcc gtggccgcca gcaaggggct 1561gccgcagcag ctgccagcac ctccggacga ggatgactca gctgccccat ccacgttgtc 1621cctgctgggc cccactttcc ccggcttaag cagctgctcc gctgacctta aagacatcct 1681gagcgaggcc agcaccatgc aactccttca gcaacagcag caggaagcag tatccgaagg 1741cagcagcagc gggagagcga gggaggcctc gggggctccc acttcctcca aggacaatta 1801cttagggggc acttcgacca tttctgacaa cgccaaggag ttgtgtaagg cagtgtcggt 1861gtccatgggc ctgggtgtgg aggcgttgga gcatctgagt ccaggggaac agcttcgggg 1921ggattgcatg tacgccccac ttttgggagt tccacccgct gtgcgtccca ctccttgtgc 1981cccattggcc gaatgcaaag gttctctgct agacgacagc gcaggcaaga gcactgaaga 2041tactgctgag tattcccctt tcaagggagg ttacaccaaa gggctagaag gcgagagcct 2101aggctgctct ggcagcgctg cagcagggag ctccgggaca cttgaactgc cgtctaccct 2161gtctctctac aagtccggag cactggacga ggcagctgcg taccagagtc gcgactacta 2221caactttcca ctggctctgg ccggaccgcc gccccctccg ccgcctcccc atccccacgc 2281tcgcatcaag ctggagaacc cgctggacta cggcagcgcc tgggcggctg cggcggcgca 2341gtgccgctat ggggacctgg cgagcctgca tggcgcgggt gcagcgggac ccggttctgg 2401gtcaccctca gccgccgctt cctcatcctg gcacactctc ttcacagccg aagaaggcca 2461gttgtatgga ccgtgtggtg gtggtggggg tggtggcggc ggcggcggcg gcggcggcgg 2521cggcggcggc ggcggcggcg gcggcgaggc gggagctgta gccccctacg gctacactcg 2581gccccctcag gggctggcgg gccaggaaag cgacttcacc gcacctgatg tgtggtaccc 2641tggcggcatg gtgagcagag tgccctatcc cagtcccact tgtgtcaaaa gcgaaatggg 2701cccctggatg gatagctact ccggacctta cggggacatg cgtttggaga ctgccaggga 2761ccatgttttg cccattgact attactttcc accccagaag acctgcctga tctgtggaga 2821tgaagcttct gggtgtcact atggagctct cacatgtgga agctgcaagg tcttcttcaa 2881aagagccgct gaagggaaac agaagtacct gtgcgccagc agaaatgatt gcactattga 2941taaattccga aggaaaaatt gtccatcttg tcgtcttcgg aaatgttatg aagcagggat 3001gactctggga gcccggaagc tgaagaaact tggtaatctg aaactacagg aggaaggaga 3061ggcttccagc accaccagcc ccactgagga gacaacccag aagctgacag tgtcacacat 3121tgaaggctat gaatgtcagc ccatctttct gaatgtcctg gaagccattg agccaggtgt 3181agtgtgtgct ggacacgaca acaaccagcc cgactccttt gcagccttgc tctctagcct 3241caatgaactg ggagagagac agcttgtaca cgtggtcaag tgggccaagg ccttgcctgg 3301cttccgcaac ttacacgtgg acgaccagat ggctgtcatt cagtactcct ggatggggct 3361catggtgttt gccatgggct ggcgatcctt caccaatgtc aactccagga tgctctactt 3421cgcccctgat ctggttttca atgagtaccg catgcacaag tcccggatgt acagccagtg 3481tgtccgaatg aggcacctct ctcaagagtt tggatggctc caaatcaccc cccaggaatt 3541cctgtgcatg aaagcactgc tactcttcag cattattcca gtggatgggc tgaaaaatca 3601aaaattcttt gatgaacttc gaatgaacta catcaaggaa ctcgatcgta tcattgcatg 3661caaaagaaaa aatcccacat cctgctcaag acgcttctac cagctcacca agctcctgga 3721ctccgtgcag cctattgcga gagagctgca tcagttcact tttgacctgc taatcaagtc 3781acacatggtg agcgtggact ttccggaaat gatggcagag atcatctctg tgcaagtgcc 3841caagatcctt tctgggaaag tcaagcccat ctatttccac acccagtgaa gcattggaaa 3901ccctatttcc ccaccccagc tcatgccccc tttcagatgt cttctgcctg ttataactct 3961gcactactcc tctgcagtgc cttggggaat ttcctctatt gatgtacagt ctgtcatgaa 4021catgttcctg aattctattt gctgggcttt ttttttctct ttctctcctt tctttttctt 4081cttccctccc tatctaaccc tcccatggca ccttcagact ttgcttccca ttgtggctcc 4141tatctgtgtt ttgaatggtg ttgtatgcct ttaaatctgt gatgatcctc atatggccca 4201gtgtcaagtt gtgcttgttt acagcactac tctgtgccag ccacacaaac gtttacttat 4261cttatgccac gggaagttta gagagctaag attatctggg gaaatcaaaa caaaaacaag 4321caaacaaaaa aaaaaagcaa aaacaaaaca aaaaataagc caaaaaacct tgctagtgtt 4381ttttcctcaa aaataaataa ataaataaat aaatacgtac atacatacac acatacatac 4441aaacatatag aaatccccaa agaggccaat agtgacgaga aggtgaaaat tgcaggccca 4501tggggagtta ctgatttttt catctcctcc ctccacggga gactttattt tctgccaatg 4561gctattgcca ttagagggca gagtgacccc agagctgagt tgggcagggg ggtggacaga 4621gaggagagga caaggagggc aatggagcat cagtacctgc ccacagcctt ggtccctggg 4681ggctagactg ctcaactgtg gagcaattca ttatactgaa aatgtgcttg ttgttgaaaa 4741tttgtctgca tgttaatgcc tcacccccaa acccttttct ctctcactct ctgcctccaa 4801cttcagattg actttcaata gtttttctaa gacctttgaa ctgaatgttc tcttcagcca 4861aaacttggcg acttccacag aaaagtctga ccactgagaa gaaggagagc agagatttaa 4921ccctttgtaa ggccccattt ggatccaggt ctgctttctc atgtgtgagt cagggaggag 4981ctggagccag aggagaagaa aatgatagct tggctgttct cctgcttagg acactgactg 5041aatagttaaa ctctcactgc cactaccttt tccccacctt taaaagacct gaatgaagtt 5101ttctgccaaa ctccgtgaag ccacaagcac cttatgtcct cccttcagtg ttttgtgggc 5161ctgaatttca tcacactgca tttcagccat ggtcatcaag cctgtttgct tcttttgggc 5221atgttcacag attctctgtt aagagccccc accaccaaga aggttagcag gccaacagct 5281ctgacatcta tctgtagatg ccagtagtca caaagatttc ttaccaactc tcagatcgct 5341ggagccctta gacaaactgg aaagaaggca tcaaagggat caggcaagct gggcgtcttg 5401cccttgtccc ccagagatga taccctccca gcaagtggag aagttctcac ttccttcttt 5461agagcagcta aaggggctac ccagatcagg gttgaagaga aaactcaatt accagggtgg 5521gaagaatgaa ggcactagaa ccagaaaccc tgcaaatgct cttcttgtca cccagcatat 5581ccacctgcag aagtcatgag aagagagaag gaacaaagag gagactctga ctactgaatt 5641aaaatcttca gcggcaaagc ctaaagccag atggacacca tctggtgagt ttactcatca 5701tcctcctctg ctgctgattc tgggctctga cattgcccat actcactcag attccccacc 5761tttgttgctg cctcttagtc agagggaggc caaaccattg agactttcta cagaaccatg 5821gcttctttcg gaaaggtctg gttggtgtgg ctccaatact ttgccaccca tgaactcagg 5881gtgtgccctg ggacactggt tttatatagt cttttggcac acctgtgttc tgttgacttc 5941gttcttcaag cccaagtgca agggaaaatg tccacctact ttctcatctt ggcctctgcc 6001tccttactta gctcttaatc tcatctgttg aactcaagaa atcaagggcc agtcatcaag 6061ctgcccattt taattgattc actctgtttg ttgagaggat agtttctgag tgacatgata 6121tgatccacaa gggtttcctt ccctgatttc tgcattgata ttaatagcca aacgaacttc 6181aaaacagctt taaataacaa gggagagggg aacctaagat gagtaatatg ccaatccaag 6241actgctggag aaaactaaag ctgacaggtt ccctttttgg ggtgggatag acatgttctg 6301gttttcttta ttattacaca atctggctca tgtacaggat cacttttagc tgttttaaac 6361agaaaaaaat atccaccact cttttcagtt acactaggtt acattttaat aggtccttta 6421catctgtttt ggaatgattt tcatcttttg tgatacacag attgaattat atcattttca 6481tatctctcct tgtaaatact agaagctctc ctttacattt ctctatcaaa tttttcatct 6541ttatgggttt cccaattgtg actcttgtct tcatgaatat atgtttttca tttgcaaaag 6601ccaaaaatca gtgaaacagc agtgtaatta aaagcaacaa ctggattact ccaaatttcc 6661aaatgacaaa actagggaaa aatagcctac acaagccttt aggcctactc tttctgtgct 6721tgggtttgag tgaacaaagg agattttagc ttggctctgt tctcccatgg atgaaaggag 6781gaggattttt tttttctttt ggccattgat gttctagcca atgtaattga cagaagtctc 6841attttgcatg cgctctgctc tacaaacaga gttggtatgg ttggtatact gtactcacct 6901gtgagggact ggccactcag acccacttag ctggtgagct agaagatgag gatcactcac 6961tggaaaagtc acaaggacca tctccaaaca agttggcagt gctcgatgtg gacgaagagt 7021gaggaagaga aaaagaagga gcaccaggga gaaggctccg tctgtgctgg gcagcagaca 7081gctgccagga tcacgaactc tgtagtcaaa gaaaagagtc gtgtggcagt ttcagctctc 7141gttcattggg cagctcgcct aggcccagcc tctgagctga catgggagtt gttggattct 7201ttgtttcata gctttttcta tgccataggc aatattgttg ttcttggaaa gtttattatt 7261tttttaactc ccttactctg agaaagggat attttgaagg actgtcatat atctttgaaa 7321aaagaaaatc tgtaatacat atatttttat gtatgttcac tggcactaaa aaatatagag 7381agcttcattc tgtcctttgg gtagttgctg aggtaattgt ccaggttgaa aaataatgtg 7441ctgatgctag agtccctctc tgtccatact ctacttctaa atacatatag gcatacatag 7501caagttttat ttgacttgta ctttaagaga aaatatgtcc accatccaca tgatgcacaa 7561atgagctaac attgagcttc aagtagcttc taagtgtttg tttcattagg cacagcacag 7621atgtggcctt tccccccttc tctcccttga tatctggcag ggcataaagg cccaggccac 7681ttcctctgcc ccttcccagc cctgcaccaa agctgcattt caggagactc tctccagaca 7741gcccagtaac tacccgagca tggcccctgc atagccctgg aaaaataaga ggctgactgt 7801ctacgaatta tcttgtgcca gttgcccagg tgagagggca ctgggccaag ggagtggttt 7861tcatgtttga cccactacaa ggggtcatgg gaatcaggaa tgccaaagca ccagatcaaa 7921tccaaaactt aaagtcaaaa taagccattc agcatgttca gtttcttgga aaaggaagtt 7981tctacccctg atgcctttgt aggcagatct gttctcacca ttaatctttt tgaaaatctt 8041ttaaagcagt ttttaaaaag agagatgaaa gcatcacatt atataaccaa agattacatt 8101gtacctgcta agataccaaa attcataagg gcaggggggg agcaagcatt agtgcctctt 8161tgataagctg tccaaagaca gactaaagga ctctgctggt gactgactta taagagcttt 8221gtgggttttt ttttccctaa taatatacat gtttagaaga attgaaaata atttcgggaa 8281aatgggatta tgggtccttc actaagtgat tttataagca gaactggctt tccttttctc 8341tagtagttgc tgagcaaatt gttgaagctc catcattgca tggttggaaa tggagctgtt 8401cttagccact gtgtttgcta gtgcccatgt tagcttatct gaagatgtga aacccttgct 8461gataagggag catttaaagt actagatttt gcactagagg gacagcaggc agaaatcctt 8521atttctgccc actttggatg gcacaaaaag ttatctgcag ttgaaggcag aaagttgaaa 8581tacattgtaa atgaatattt gtatccatgt ttcaaaattg aaatatatat atatatatat 8641atatatatat atatatatat atagtgtgtg tgtgtgttct gatagcttta actttctctg 8701catctttata tttggttcca gatcacacct gatgccatgt acttgtgaga gaggatgcag 8761ttttgttttg gaagctctct cagaacaaac aagacacctg gattgatcag ttaactaaaa 8821gttttctccc ctattgggtt tgacccacag gtcctgtgaa ggagcagagg gataaaaaga 8881gtagaggaca tgatacattg tactttacta gttcaagaca gatgaatgtg gaaagcataa 8941aaactcaatg gaactgactg agatttacca cagggaaggc ccaaacttgg ggccaaaagc 9001ctacccaagt gattgaccag tggcccccta atgggacctg agctgttgga agaagagaac 9061tgttccttgg tcttcaccat ccttgtgaga gaagggcagt ttcctgcatt ggaacctgga 9121gcaagcgctc tatctttcac acaaattccc tcacctgaga ttgaggtgct cttgttactg 9181ggtgtctgtg tgctgtaatt ctggttttgg atatgttctg taaagatttt gacaaatgaa 9241aatgtgtttt tctctgttaa aacttgtcag agtactagaa gttgtatctc tgtaggtgca 9301ggtccatttc tgcccacagg tagggtgttt ttctttgatt aagagattga cacttctgtt 9361gcctaggacc tcccaactca accatttcta ggtgaaggca gaaaaatcca cattagttac 9421tcctcttcag acatttcagc tgagataaca aatcttttgg aattttttca cccatagaaa 9481gagtggtaga tatttgaatt tagcaggtgg agtttcatag taaaaacagc ttttgactca 9541gctttgattt atcctcattt gatttggcca gaaagtaggt aatatgcatt gattggcttc 9601tgattccaat tcagtatagc aaggtgctag gttttttcct ttccccacct gtctcttagc 9661ctggggaatt aaatgagaag ccttagaatg ggtggccctt gtgacctgaa acacttccca 9721cataagctac ttaacaagat tgtcatggag ctgcagattc cattgcccac caaagactag 9781aacacacaca tatccataca ccaaaggaaa gacaattctg aaatgctgtt tctctggtgg 9841ttccctctct ggctgctgcc tcacagtatg ggaacctgta ctctgcagag gtgacaggcc 9901agatttgcat tatctcacaa ccttagccct tggtgctaac tgtcctacag tgaagtgcct 9961ggggggttgt cctatcccat aagccacttg gatgctgaca gcagccacca tcagaatgac 10021ccacgcaaaa aaaagaaaaa aaaaattaaa aagtcccctc acaacccagt gacacctttc 10081tgctttcctc tagactggaa cattgattac ggagtgcctc agacatgaca ttcttgtgct 10141gtccttggaa ttaatctggc agcaggaggc agcagactat gtaaacagac ataaaaatta 10201attttcaata ttgaaggaaa aaagaaataa gaagagagac agaaagaaac catcacacaa 10261agattttctt aaaagaaaca attttgcttc aaatctcttt agatggggct catttctcac 10321ggtggcactt ggcctccact gggcagcagc accagctcca agcgctagtc ttctgttctc 10381tttttgtaat cttggaatct tttgttgctc taaatacaat taaaaatggc agaaacttgt 10441ttgttggact acatgtgtga ctttgggtct gtctctgcct ctgctttcac aaatgtcatc 10501cattgtgtaa aatattggct tactggtctc ccagctaaaa cttggccaca tcccctgtta 10561tggctgcagc atcgagttat tgttaacaaa gagacccaac aaaagctgct aatgtcctct 10621tatcattgtt gttaatttgt taaaacataa agaaatctaa aatttcaSEQ ID NO: 50 Human AR Isoform 2 Amino Acid Sequence (NP_001011645.1) 1milwlhslet ardhvlpidy yfppqktcli cgdeasgchy galtcgsckv ffkraaegkq 61kylcasrndc tidkfrrknc pscrlrkcye agmtlgarkl kklgnlklqe egeassttsp 121teettqkltv shiegyecqp iflnvleaie pgvvcaghdn nqpdsfaall sslnelgerq 181lvhvvkwaka lpgfrnlhvd dqmaviqysw mglmvfamgw rsftnvnsrm lyfapdlvfn 241eyrmhksrmy sqcvrmrhls qefgwlqitp qeflcmkall lfsiipvdgl knqkffdelr 301mnyikeldri iackrknpts csrrfyqltk lldsvqpiar elhqftfdll ikshmvsvdf 361pemmaeiisv qvpkilsgkv kpiyfhtqSEQ ID NO: 51 Human AR transcript variant 2 cDNA sequence (NM_001011645.3;CDS: 2308 . . . 3474) 1gcggagagaa ccctctgttt tcccccactc tctctccacc tcctcctgcc ttccccaccc 61cgagtgcgga gccagagatc aaaagatgaa aaggcagtca ggtcttcagt agccaaaaaa 121caaaacaaac aaaaacaaaa aagccgaaat aaaagaaaaa gataataact cagttcttat 181ttgcacctac ttcagtggac actgaatttg gaaggtggag gattttgttt ttttctttta 241agatctgggc atcttttgaa tctacccttc aagtattaag agacagactg tgagcctagc 301agggcagatc ttgtccaccg tgtgtcttct tctgcacgag actttgaggc tgtcagagcg 361ctttttgcgt ggttgctccc gcaagtttcc ttctctggag cttcccgcag gtgggcagct 421agctgcagcg actaccgcat catcacagcc tgttgaactc ttctgagcaa gagaagggga 481ggcggggtaa gggaagtagg tggaagattc agccaagctc aaggatggaa gtgcagttag 541ggctgggaag ggtctaccct cggccgccgt ccaagaccta ccgaggagct ttccagaatc 601tgttccagag cgtgcgcgaa gtgatccaga acccgggccc caggcaccca gaggccgcga 661gcgcagcacc tcccggcgcc agtttgctgc tgctgcagca gcagcagcag cagcagcagc 721agcagcagca gcagcagcag cagcagcagc agcagcagca gcaagagact agccccaggc 781agcagcagca gcagcagggt gaggatggtt ctccccaagc ccatcgtaga ggccccacag 841gctacctggt cctggatgag gaacagcaac cttcacagcc gcagtcggcc ctggagtgcc 901accccgagag aggttgcgtc ccagagcctg gagccgccgt ggccgccagc aaggggctgc 961cgcagcagct gccagcacct ccggacgagg atgactcagc tgccccatcc acgttgtccc 1021tgctgggccc cactttcccc ggcttaagca gctgctccgc tgaccttaaa gacatcctga 1081gcgaggccag caccatgcaa ctccttcagc aacagcagca ggaagcagta tccgaaggca 1141gcagcagcgg gagagcgagg gaggcctcgg gggctcccac ttcctccaag gacaattact 1201tagggggcac ttcgaccatt tctgacaacg ccaaggagtt gtgtaaggca gtgtcggtgt 1261ccatgggcct gggtgtggag gcgttggagc atctgagtcc aggggaacag cttcgggggg 1321attgcatgta cgccccactt ttgggagttc cacccgctgt gcgtcccact ccttgtgccc 1381cattggccga atgcaaaggt tctctgctag acgacagcgc aggcaagagc actgaagata 1441ctgctgagta ttcccctttc aagggaggtt acaccaaagg gctagaaggc gagagcctag 1501gctgctctgg cagcgctgca gcagggagct ccgggacact tgaactgccg tctaccctgt 1561ctctctacaa gtccggagca ctggacgagg cagctgcgta ccagagtcgc gactactaca 1621actttccact ggctctggcc ggaccgccgc cccctccgcc gcctccccat ccccacgctc 1681gcatcaagct ggagaacccg ctggactacg gcagcgcctg ggcggctgcg gcggcgcagt 1741gccgctatgg ggacctggcg agcctgcatg gcgcgggtgc agcgggaccc ggttctgggt 1801caccctcagc cgccgcttcc tcatcctggc acactctctt cacagccgaa gaaggccagt 1861tgtatggacc gtgtggtggt ggtgggggtg gtggcggcgg cggcggcggc ggcggcggcg 1921gcggcggcgg cggcggcggc ggcgaggcgg gagctgtagc cccctacggc tacactcggc 1981cccctcaggg gctggcgggc caggaaagcg acttcaccgc acctgatgtg tggtaccctg 2041gcggcatggt gagcagagtg ccctatccca gtcccacttg tgtcaaaagc gaaatgggcc 2101cctggatgga tagctactcc ggaccttacg gggacatgcg taggtgctgc gagcagagag 2161ggattcctcg gaggtcatct gttccatctt cttgcctatg caaatgcctg cctgaagctg 2221ctggaggctg gctttgtacc ggactttgta cagggaacca gggaaacgaa tgcagagtgc 2281tcctgacatt gcctgtcact ttttcccatg atactctggc ttcacagttt ggagactgcc 2341agggaccatg ttttgcccat tgactattac tttccacccc agaagacctg cctgatctgt 2401ggagatgaag cttctgggtg tcactatgga gctctcacat gtggaagctg caaggtcttc 2461ttcaaaagag ccgctgaagg gaaacagaag tacctgtgcg ccagcagaaa tgattgcact 2521attgataaat tccgaaggaa aaattgtcca tcttgtcgtc ttcggaaatg ttatgaagca 2581gggatgactc tgggagcccg gaagctgaag aaacttggta atctgaaact acaggaggaa 2641ggagaggctt ccagcaccac cagccccact gaggagacaa cccagaagct gacagtgtca 2701cacattgaag gctatgaatg tcagcccatc tttctgaatg tcctggaagc cattgagcca 2761ggtgtagtgt gtgctggaca cgacaacaac cagcccgact cctttgcagc cttgctctct 2821agcctcaatg aactgggaga gagacagctt gtacacgtgg tcaagtgggc caaggccttg 2881cctggcttcc gcaacttaca cgtggacgac cagatggctg tcattcagta ctcctggatg 2941gggctcatgg tgtttgccat gggctggcga tccttcacca atgtcaactc caggatgctc 3001tacttcgccc ctgatctggt tttcaatgag taccgcatgc acaagtcccg gatgtacagc 3061cagtgtgtcc gaatgaggca cctctctcaa gagtttggat ggctccaaat caccccccag 3121gaattcctgt gcatgaaagc actgctactc ttcagcatta ttccagtgga tgggctgaaa 3181aatcaaaaat tctttgatga acttcgaatg aactacatca aggaactcga tcgtatcatt 3241gcatgcaaaa gaaaaaatcc cacatcctgc tcaagacgct tctaccagct caccaagctc 3301ctggactccg tgcagcctat tgcgagagag ctgcatcagt tcacttttga cctgctaatc 3361aagtcacaca tggtgagcgt ggactttccg gaaatgatgg cagagatcat ctctgtgcaa 3421gtgcccaaga tcctttctgg gaaagtcaag cccatctatt tccacaccca gtgaagcatt 3481ggaaacccta tttccccacc ccagctcatg ccccctttca gatgtcttct gcctgttata 3541actctgcact actcctctgc agtgccttgg ggaatttcct ctattgatgt acagtctgtc 3601atgaacatgt tcctgaattc tatttgctgg gctttttttt tctctttctc tcctttcttt 3661ttcttcttcc ctccctatct aaccctccca tggcaccttc agactttgct tcccattgtg 3721gctcctatct gtgttttgaa tggtgttgta tgcctttaaa tctgtgatga tcctcatatg 3781gcccagtgtc aagttgtgct tgtttacagc actactctgt gccagccaca caaacgttta 3841cttatcttat gccacgggaa gtttagagag ctaagattat ctggggaaat caaaacaaaa 3901acaagcaaac aaaaaaaaaa agcaaaaaca aaacaaaaaa taagccaaaa aaccttgcta 3961gtgttttttc ctcaaaaata aataaataaa taaataaata cgtacataca tacacacata 4021catacaaaca tatagaaatc cccaaagagg ccaatagtga cgagaaggtg aaaattgcag 4081gcccatgggg agttactgat tttttcatct cctccctcca cgggagactt tattttctgc 4141caatggctat tgccattaga gggcagagtg accccagagc tgagttgggc aggggggtgg 4201acagagagga gaggacaagg agggcaatgg agcatcagta cctgcccaca gccttggtcc 4261ctgggggcta gactgctcaa ctgtggagca attcattata ctgaaaatgt gcttgttgtt 4321gaaaatttgt ctgcatgtta atgcctcacc cccaaaccct tttctctctc actctctgcc 4381tccaacttca gattgacttt caatagtttt tctaagacct ttgaactgaa tgttctcttc 4441agccaaaact tggcgacttc cacagaaaag tctgaccact gagaagaagg agagcagaga 4501tttaaccctt tgtaaggccc catttggatc caggtctgct ttctcatgtg tgagtcaggg 4561aggagctgga gccagaggag aagaaaatga tagcttggct gttctcctgc ttaggacact 4621gactgaatag ttaaactctc actgccacta ccttttcccc acctttaaaa gacctgaatg 4681aagttttctg ccaaactccg tgaagccaca agcaccttat gtcctccctt cagtgttttg 4741tgggcctgaa tttcatcaca ctgcatttca gccatggtca tcaagcctgt ttgcttcttt 4801tgggcatgtt cacagattct ctgttaagag cccccaccac caagaaggtt agcaggccaa 4861cagctctgac atctatctgt agatgccagt agtcacaaag atttcttacc aactctcaga 4921tcgctggagc ccttagacaa actggaaaga aggcatcaaa gggatcaggc aagctgggcg 4981tcttgccctt gtcccccaga gatgataccc tcccagcaag tggagaagtt ctcacttcct 5041tctttagagc agctaaaggg gctacccaga tcagggttga agagaaaact caattaccag 5101ggtgggaaga atgaaggcac tagaaccaga aaccctgcaa atgctcttct tgtcacccag 5161catatccacc tgcagaagtc atgagaagag agaaggaaca aagaggagac tctgactact 5221gaattaaaat cttcagcggc aaagcctaaa gccagatgga caccatctgg tgagtttact 5281catcatcctc ctctgctgct gattctgggc tctgacattg cccatactca ctcagattcc 5341ccacctttgt tgctgcctct tagtcagagg gaggccaaac cattgagact ttctacagaa 5401ccatggcttc tttcggaaag gtctggttgg tgtggctcca atactttgcc acccatgaac 5461tcagggtgtg ccctgggaca ctggttttat atagtctttt ggcacacctg tgttctgttg 5521acttcgttct tcaagcccaa gtgcaaggga aaatgtccac ctactttctc atcttggcct 5581ctgcctcctt acttagctct taatctcatc tgttgaactc aagaaatcaa gggccagtca 5641tcaagctgcc cattttaatt gattcactct gtttgttgag aggatagttt ctgagtgaca 5701tgatatgatc cacaagggtt tccttccctg atttctgcat tgatattaat agccaaacga 5761acttcaaaac agctttaaat aacaagggag aggggaacct aagatgagta atatgccaat 5821ccaagactgc tggagaaaac taaagctgac aggttccctt tttggggtgg gatagacatg 5881ttctggtttt ctttattatt acacaatctg gctcatgtac aggatcactt ttagctgttt 5941taaacagaaa aaaatatcca ccactctttt cagttacact aggttacatt ttaataggtc 6001ctttacatct gttttggaat gattttcatc ttttgtgata cacagattga attatatcat 6061tttcatatct ctccttgtaa atactagaag ctctccttta catttctcta tcaaattttt 6121catctttatg ggtttcccaa ttgtgactct tgtcttcatg aatatatgtt tttcatttgc 6181aaaagccaaa aatcagtgaa acagcagtgt aattaaaagc aacaactgga ttactccaaa 6241tttccaaatg acaaaactag ggaaaaatag cctacacaag cctttaggcc tactctttct 6301gtgcttgggt ttgagtgaac aaaggagatt ttagcttggc tctgttctcc catggatgaa 6361aggaggagga tttttttttt cttttggcca ttgatgttct agccaatgta attgacagaa 6421gtctcatttt gcatgcgctc tgctctacaa acagagttgg tatggttggt atactgtact 6481cacctgtgag ggactggcca ctcagaccca cttagctggt gagctagaag atgaggatca 6541ctcactggaa aagtcacaag gaccatctcc aaacaagttg gcagtgctcg atgtggacga 6601agagtgagga agagaaaaag aaggagcacc agggagaagg ctccgtctgt gctgggcagc 6661agacagctgc caggatcacg aactctgtag tcaaagaaaa gagtcgtgtg gcagtttcag 6721ctctcgttca ttgggcagct cgcctaggcc cagcctctga gctgacatgg gagttgttgg 6781attctttgtt tcatagcttt ttctatgcca taggcaatat tgttgttctt ggaaagttta 6841ttattttttt aactccctta ctctgagaaa gggatatttt gaaggactgt catatatctt 6901tgaaaaaaga aaatctgtaa tacatatatt tttatgtatg ttcactggca ctaaaaaata 6961tagagagctt cattctgtcc tttgggtagt tgctgaggta attgtccagg ttgaaaaata 7021atgtgctgat gctagagtcc ctctctgtcc atactctact tctaaataca tataggcata 7081catagcaagt tttatttgac ttgtacttta agagaaaata tgtccaccat ccacatgatg 7141cacaaatgag ctaacattga gcttcaagta gcttctaagt gtttgtttca ttaggcacag 7201cacagatgtg gcctttcccc ccttctctcc cttgatatct ggcagggcat aaaggcccag 7261gccacttcct ctgccccttc ccagccctgc accaaagctg catttcagga gactctctcc 7321agacagccca gtaactaccc gagcatggcc cctgcatagc cctggaaaaa taagaggctg 7381actgtctacg aattatcttg tgccagttgc ccaggtgaga gggcactggg ccaagggagt 7441ggttttcatg tttgacccac tacaaggggt catgggaatc aggaatgcca aagcaccaga 7501tcaaatccaa aacttaaagt caaaataagc cattcagcat gttcagtttc ttggaaaagg 7561aagtttctac ccctgatgcc tttgtaggca gatctgttct caccattaat ctttttgaaa 7621atcttttaaa gcagttttta aaaagagaga tgaaagcatc acattatata accaaagatt 7681acattgtacc tgctaagata ccaaaattca taagggcagg gggggagcaa gcattagtgc 7741ctctttgata agctgtccaa agacagacta aaggactctg ctggtgactg acttataaga 7801gctttgtggg tttttttttc cctaataata tacatgttta gaagaattga aaataatttc 7861gggaaaatgg gattatgggt ccttcactaa gtgattttat aagcagaact ggctttcctt 7921ttctctagta gttgctgagc aaattgttga agctccatca ttgcatggtt ggaaatggag 7981ctgttcttag ccactgtgtt tgctagtgcc catgttagct tatctgaaga tgtgaaaccc 8041ttgctgataa gggagcattt aaagtactag attttgcact agagggacag caggcagaaa 8101tccttatttc tgcccacttt ggatggcaca aaaagttatc tgcagttgaa ggcagaaagt 8161tgaaatacat tgtaaatgaa tatttgtatc catgtttcaa aattgaaata tatatatata 8221tatatatata tatatatata tatatatagt gtgtgtgtgt gttctgatag ctttaacttt 8281ctctgcatct ttatatttgg ttccagatca cacctgatgc catgtacttg tgagagagga 8341tgcagttttg ttttggaagc tctctcagaa caaacaagac acctggattg atcagttaac 8401taaaagtttt ctcccctatt gggtttgacc cacaggtcct gtgaaggagc agagggataa 8461aaagagtaga ggacatgata cattgtactt tactagttca agacagatga atgtggaaag 8521cataaaaact caatggaact gactgagatt taccacaggg aaggcccaaa cttggggcca 8581aaagcctacc caagtgattg accagtggcc ccctaatggg acctgagctg ttggaagaag 8641agaactgttc cttggtcttc accatccttg tgagagaagg gcagtttcct gcattggaac 8701ctggagcaag cgctctatct ttcacacaaa ttccctcacc tgagattgag gtgctcttgt 8761tactgggtgt ctgtgtgctg taattctggt tttggatatg ttctgtaaag attttgacaa 8821atgaaaatgt gtttttctct gttaaaactt gtcagagtac tagaagttgt atctctgtag 8881gtgcaggtcc atttctgccc acaggtaggg tgtttttctt tgattaagag attgacactt 8941ctgttgccta ggacctccca actcaaccat ttctaggtga aggcagaaaa atccacatta 9001gttactcctc ttcagacatt tcagctgaga taacaaatct tttggaattt tttcacccat 9061agaaagagtg gtagatattt gaatttagca ggtggagttt catagtaaaa acagcttttg 9121actcagcttt gatttatcct catttgattt ggccagaaag taggtaatat gcattgattg 9181gcttctgatt ccaattcagt atagcaaggt gctaggtttt ttcctttccc cacctgtctc 89241ttagcctggg gaattaaatg agaagcctta gaatgggtgg cccttgtgac ctgaaacact 9301tcccacataa gctacttaac aagattgtca tggagctgca gattccattg cccaccaaag 9361actagaacac acacatatcc atacaccaaa ggaaagacaa ttctgaaatg ctgtttctct 9421ggtggttccc tctctggctg ctgcctcaca gtatgggaac ctgtactctg cagaggtgac 9481aggccagatt tgcattatct cacaacctta gcccttggtg ctaactgtcc tacagtgaag 9541tgcctggggg gttgtcctat cccataagcc acttggatgc tgacagcagc caccatcaga 9601atgacccacg caaaaaaaag aaaaaaaaaa ttaaaaagtc ccctcacaac ccagtgacac 9661ctttctgctt tcctctagac tggaacattg attagggagt gcctcagaca tgacattctt 9721gtgctgtcct tggaattaat ctggcagcag gagggagcag actatgtaaa cagagataaa 9781aattaatttt caatattgaa ggaaaaaaga aataagaaga gagagagaaa gaaagcatca 9841cacaaagatt ttcttaaaag aaacaatttt gcttgaaatc tctttagatg gggctcattt 9901ctcacggtgg cacttggcct ccactgggca gcaggaccag ctccaagcgc tagtgttctg 9961ttctcttttt gtaatcttgg aatcttttgt tgctctaaat acaattaaaa atggcagaaa 10021cttgtttgtt ggactacatg tgtgactttg ggtctgtctc tgcctctgct ttcagaaatg 10081tcatccattg tgtaaaatat tggcttactg gtctgccagc taaaacttgg ccacatcccc 10141tgttatggct gcaggatcga gttattgtta acaaagagac ccaagaaaag ctgctaatgt 10201cctcttatca ttgttgttaa tttgttaaaa cataaagaaa tctaaaattt caaaaaaSEQ ID NO: 52 Human AR Isoform 3 Amino Acid Sequence (NP_001334990.1) 1mevqlglgrv yprppsktyr gafqnlfqsv reviqnpgpr hpeaasaapp gasllllqqq 61qqqqqqqqqq qqqqqqqqqq etsprqqqqq qgedgspqah rrgptgylvl deeqqpsqpq 121salechperg cvpepgaava askglpqqlp appdeddsaa pstlsllgpt fpglsscsad 181lkdilseast mqllqqqqqe avsegsssgr areasgapts skdnylggts tisdnakelc 241kavsvsmglg vealehlspg eqlrgdcmya pllgvppavr ptpcaplaec kgsllddsag 301kstedtaeys pfkggytkgl egeslgcsgs aaagssgtle lpstlslyks galdeaaayq 361srdyynfpla lagppppppp phpharikle npldygsawa aaaaqcrygd laslhgagaa 421gpgsgspsaa assswhtlft aeegqlygpc gggggggggg gggggggggg gggeagavap 481ygytrppqgl agqesdftap dvwypggmvs rvpypsptcv ksemgpwmds ysgpygdmrl 541etardhvlpi dyyfppqktc licgdeasgc hygaltcgsc kvffkraaeg kqkylcasrn 601dctidkfrrk ncpscrlrkc yeagmtlgek frvgnckhlk mtrpSEQ ID NO: 53 Human AR transcript variant 3 cDNA sequence (NM_001348061.1;CDS: 525 . . . 2459) 1gcggagagaa ccctctgttt tcccccactc tctctccacc tcctcctgcc ttccccaccc 61cgagtgcgga gccagagatc aaaagatgaa aaggcagtca ggtcttcagt agccaaaaaa 121caaaacaaac aaaaacaaaa aagccgaaat aaaagaaaaa gataataact cagttcttat 181ttgcacctac ttcagtggac actgaatttg gaaggtggag gattttgttt ttttctttta 241agatctgggc atcttttgaa tctacccttc aagtattaag agacagactg tgagcctagc 301agggcagatc ttgtccaccg tgtgtcttct tctgcacgag actttgaggc tgtcagagcg 361ctttttgcgt ggttgctccc gcaagtttcc ttctctggag cttcccgcag gtgggcagct 421agctgcagcg actaccgcat catcacagcc tgttgaactc ttctgagcaa gagaagggga 481ggcggggtaa gggaagtagg tggaagattc agccaagctc aaggatggaa gtgcagttag 541ggctgggaag ggtctaccct cggccgccgt ccaagaccta ccgaggagct ttccagaatc 601tgttccagag cgtgcgcgaa gtgatccaga acccgggccc caggcaccca gaggccgcga 661gcgcagcacc tcccggcgcc agtttgctgc tgctgcagca gcagcagcag cagcagcagc 721agcagcagca gcagcagcag cagcagcagc agcagcagca gcaagagact agccccaggc 781agcagcagca gcagcagggt gaggatggtt ctccccaagc ccatcgtaga ggccccacag 841gctacctggt cctggatgag gaacagcaac cttcacagcc gcagtcggcc ctggagtgcc 901accccgagag aggttgcgtc ccagagcctg gagccgccgt ggccgccagc aaggggctgc 961cgcagcagct gccagcacct ccggacgagg atgactcagc tgccccatcc acgttgtccc 1021tgctgggccc cactttcccc ggcttaagca gctgctccgc tgaccttaaa gacatcctga 1081gcgaggccag caccatgcaa ctccttcagc aacagcagca ggaagcagta tccgaaggca 1141gcagcagcgg gagagcgagg gaggcctcgg gggctcccac ttcctccaag gacaattact 1201tagggggcac ttcgaccatt tctgacaacg ccaaggagtt gtgtaaggca gtgtcggtgt 1261ccatgggcct gggtgtggag gcgttggagc atctgagtcc aggggaacag cttcgggggg 1321attgcatgta cgccccactt ttgggagttc cacccgctgt gcgtcccact ccttgtgccc 1381cattggccga atgcaaaggt tctctgctag acgacagcgc aggcaagagc actgaagata 1441ctgctgagta ttcccctttc aagggaggtt acaccaaagg gctagaaggc gagagcctag 1501gctgctctgg cagcgctgca gcagggagct ccgggacact tgaactgccg tctaccctgt 1561ctctctacaa gtccggagca ctggacgagg cagctgcgta ccagagtcgc gactactaca 1621actttccact ggctctggcc ggaccgccgc cccctccgcc gcctccccat ccccacgctc 1681gcatcaagct ggagaacccg ctggactacg gcagcgcctg ggcggctgcg gcggcgcagt 1741gccgctatgg ggacctggcg agcctgcatg gcgcgggtgc agcgggaccc ggttctgggt 1801caccctcagc cgccgcttcc tcatcctggc acactctctt cacagccgaa gaaggccagt 1861tgtatggacc gtgtggtggt ggtgggggtg gtggcggcgg cggcggcggc ggcggcggcg 1921gcggcggcgg cggcggcggc ggcgaggcgg gagctgtagc cccctacggc tacactcggc 1981cccctcaggg gctggcgggc caggaaagcg acttcaccgc acctgatgtg tggtaccctg 2041gcggcatggt gagcagagtg ccctatccca gtcccacttg tgtcaaaagc gaaatgggcc 2101cctggatgga tagctactcc ggaccttacg gggacatgcg tttggagact gccagggacc 2161atgttttgcc cattgactat tactttccac cccagaagac ctgcctgatc tgtggagatg 2221aagcttctgg gtgtcactat ggagctctca catgtggaag ctgcaaggtc ttcttcaaaa 2281gagccgctga agggaaacag aagtacctgt gcgccagcag aaatgattgc actattgata 2341aattccgaag gaaaaattgt ccatcttgtc gtcttcggaa atgttatgaa gcagggatga 2401ctctgggaga aaaattccgg gttggcaatt gcaagcatct caaaatgacc agaccctgaa 2461gaaaggctga cttgcctcat tcaaaatgag ggctctagag ggctctagtg gatagtctgg 2521agaaacctgg cgtctgaggc ttaggagctt aggtttttgc tcctcaacac agactttgac 2581gttggggttg ggggctactc tcttgattgc tgactccctc cagcgggacc aatagtgttt 2641tcctacctca cagggatgtt gtgaggacgg gctgtagaag taatagtggt taccattcat 2701gtagttgtga gtatcatgat tattgtttcc tgtaatgtgg cttggcattg gcaaagtgct 2761ttttgattgt tcttgatcac atatgatggg ggccaggcac tgactcaggc ggatgcagtg 2821aagctctggc tcagtcgctt gcttttcgtg gtgtgctgcc aggaagaaac tttgctgatg 2881ggactcaagg tgtcaccttg gacaagaagc aactgtgtct gtctgaggtt cctgtggcca 2941tctttatttg tgtattaggc aattcgtatt tcccccttag gttctagcct tctggatccc 3001agccagtgac ctagatctta gcctcaggcc ctgtcactga gctgaaggta gtagctgatc 3061cacagaagtt cagtaaacaa ggaccagatt tctgcttctc caggagaaga agccagccaa 3121cccctctctt caaacacact gagagactac agtccgactt tccctcttac atctagcctt 3181actgtagcca cactccttga ttgctctctc acatcacatg cttctcttca tcagttgtaa 3241gcctctcatt cttctcccaa gccagactca aatattgtat tgatgtcaaa gaagaatcac 3301ttagagtttg gaatatcttg ttctctctct gctccatagc ttccatattg acaccagttt 3361ctttctagtg gagaagtgga gtctgtgaag ccagggaaac acacatgtga gagtcagaag 3421gactctccct gacttgcctg gggcctgtct ttcccacctt ctccagtctg tctaaacaca 3481cacacacaca cacacacaca cacacacacg ctctctctct ctctcccccc ccaacacaca 3541cacactctct ctctctctca cacacacaca catacacaca cacttctttc tctttcccct 3601gactcagcaa cattctggag aaaagccaag gaaggacttc aggaggggag tttccccctt 3661ctcagggcag aattttaatc tccagaccaa caagaagttc cctaatgtgg attgaaaggc 3721taatgaggtt tatttttaac tactttctat ttgtttgaat gttgcatatt tctactagtg 3781aaattttccc ttaataaagc cattaataca ccSEQ ID NO: 54 Human AR Isoform 4 Amino Acid Sequence (NP_001334992.1) 1mevqlglgrv yprppsktyr gafqnlfqsv reviqnpgpr hpeaasaapp gasllllqqq 61qqqqqqqqqq qqqqqqqqqq etsprqqqqq qgedgspqah rrgptgylvl deeqqpsqpq 121salechperg cvpepgaava askglpqqlp appdeddsaa pstlsllgpt fpglsscsad 181lkdilseast mqllqqqqqe avsegsssgr areasgapts skdnylggts tisdnakelc 241kavsvsmglg vealehlspg eqlrgdcmya pllgvppavr ptpcaplaec kgsllddsag 301kstedtaeys pfkggytkgl egeslgcsgs aaagssgtle lpstlslyks galdeaaayq 361srdyynfpla lagppppppp phpharikle npldygsawa aaaaqcrygd laslhgagaa 421gpgsgsgsaa assswhtlft aeegqlygpc gggggggggg gggggggggg gggeagavap 481ygytrppqgl agqesdftap dvwypggmvs rvpypsptcv ksemgpwmds ysgpygdmrl 541etardhvlpi dyyfppqktc licgdeasgc hygaltcgsc kvffkraaeg kqkylcasrn 601dctidkfrrk ncpscrlrkc yeagmtlgaa vvvserilrv fgvsewlpSEQ ID NO: 55 Human AR transcript variant 4 cDNA sequence (NM_001348063.1;CDS: 525 . . . 2471) 1gcggagagaa ccctctgttt tcccccactc tctctccacc tcctcctgcc ttccccaccc 61cgagtgcgga gccagagatc aaaagatgaa aaggcagtca ggtcttcagt agccaaaaaa 121caaaacaaac aaaaacaaaa aagccgaaat aaaagaaaaa gataataact cagttcttat 181ttgcacctac ttcagtggac actgaatttg gaaggtggag gattttgttt ttttctttta 241agatctgggc atcttttgaa tctacccttc aagtattaag agacagactg tgagcctagc 301agggcagatc ttgtccaccg tgtgtcttct tctgcacgag actttgaggc tgtcagagcg 361ctttttgcgt ggttgctccc gcaagtttcc ttctctggag cttcccgcag gtgggcagct 421agctgcagcg actaccgcat catcacagcc tgttgaactc ttctgagcaa gagaagggga 481ggcggggtaa gggaagtagg tggaagattc agccaagctc aaggatggaa gtgcagttag 541ggctgggaag ggtctaccct cggccgccgt ccaagaccta ccgaggagct ttccagaatc 601tgttccagag cgtgcgcgaa gtgatccaga acccgggccc caggcaccca gaggccgcga 661gcgcagcacc tcccggcgcc agtttgctgc tgctgcagca gcagcagcag cagcagcagc 721agcagcagca gcagcagcag cagcagcagc agcagcagca gcaagagact agccccaggc 781agcagcagca gcagcagggt gaggatggtt ctccccaagc ccatcgtaga ggccccacag 841gctacctggt cctggatgag gaacagcaac cttcacagcc gcagtcggcc ctggagtgcc 901accccgagag aggttgcgtc ccagagcctg gagccgccgt ggccgccagc aaggggctgc 961cgcagcagct gccagcacct ccggacgagg atgactcagc tgccccatcc acgttgtccc 1021tgctgggccc cactttcccc ggcttaagca gctgctccgc tgaccttaaa gacatcctga 1081gcgaggccag caccatgcaa ctccttcagc aacagcagca ggaagcagta tccgaaggca 1141gcagcagcgg gagagcgagg gaggcctcgg gggctcccac ttcctccaag gacaattact 1201tagggggcac ttcgaccatt tctgacaacg ccaaggagtt gtgtaaggca gtgtcggtgt 1261ccatgggcct gggtgtggag gcgttggagc atctgagtcc aggggaacag cttcgggggg 1321attgcatgta cgccccactt ttgggagttc cacccgctgt gcgtcccact ccttgtgccc 1381cattggccga atgcaaaggt tctctgctag acgacagcgc aggcaagagc actgaagata 1441ctgctgagta ttcccctttc aagggaggtt acaccaaagg gctagaaggc gagagcctag 1501gctgctctgg cagcgctgca gcagggagct ccgggacact tgaactgccg tctaccctgt 1561ctctctacaa gtccggagca ctggacgagg cagctgcgta ccagagtcgc gactactaca 1621actttccact ggctctggcc ggaccgccgc cccctccgcc gcctccccat ccccacgctc 1681gcatcaagct ggagaacccg ctggactacg gcagcgcctg ggcggctgcg gcggcgcagt 1741gccgctatgg ggacctggcg agcctgcatg gcgcgggtgc agcgggaccc ggttctgggt 1801caccctcagc cgccgcttcc tcatcctggc acactctctt cacagccgaa gaaggccagt 1861tgtatggacc gtgtggtggt ggtgggggtg gtggcggcgg cggcggcggc ggcggcggcg 1921gcggcggcgg cggcggcggc ggcgaggcgg gagctgtagc cccctacggc tacactcggc 1981cccctcaggg gctggcgggc caggaaagcg acttcaccgc acctgatgtg tggtaccctg 2041gcggcatggt gagcagagtg ccctatccca gtcccacttg tgtcaaaagc gaaatgggcc 2101cctggatgga tagctactcc ggaccttacg gggacatgcg tttggagact gccagggacc 2161atgttttgcc cattgactat tactttccac cccagaagac ctgcctgatc tgtggagatg 2221aagcttctgg gtgtcactat ggagctctca catgtggaag ctgcaaggtc ttcttcaaaa 2281gagccgctga agggaaacag aagtacctgt gcgccagcag aaatgattgc actattgata 2341aattccgaag gaaaaattgt ccatcttgtc gtcttcggaa atgttatgaa gcagggatga 2401ctctgggagc agctgttgtt gtttctgaaa gaatcttgag ggtgtttgga gtctcagaat 2461ggcttcctta aagactacct tcagactctc agctgctcat ccacaacaga gatcagcctt 2521tctttgtaga tgattcattc ctggctgcat ttgaaaacca catattgtta attgcttgac 2581gaatttaaat cccttgacta cttttcattt caaaaaaaaa aaaaaaaSEQ ID NO: 56 Human AR Isoform 5 Amino Acid Sequence (NP_001334993.1) 1mevqlglgrv yprppsktyr gafqnlfqsv reviqnpgpr hpeaasaapp gasllllqqq 61qqqqqqqqqq qqqqqqqqqq etsprqqqqq qgedgspqah rrgptgylvl deeqqpsqpq 121salechperg cvpepgaava askglpqqlp appdeddsaa pstlsllgpt fpglsscsad 181lkdilseast mqllqqqqqe avsegsssgr areasgapts skdnylggts tisdnakelc 241kavsvsmglg vealehlspg eqlrgdcmya pllgvppavr ptpcaplaec kgsllddsag 301kstedtaeys pfkggytkgl egeslgcsgs aaagssgtle lpstlslyks galdeaaayq 361srdyynfpla lagppppppp phpharikle npldygsawa aaaaqcrygd laslhgagaa 421gpgsgspsaa assswhtlft aeegqlygpc gggggggggg gggggggggg gggeagavap 481ygytrppqgl agqesdftap dvwypgfmvs rvpypsptcv ksemgpwmds ysgpygdmrn 541trrkrlwkli irsinscics pretevpvrq qkSEQ ID NO: 57 Human AR transcript variant 5 cDNA sequence (NM_001348064.1;CDS: 525 . . . 2243) 1gcggagagaa ccctctgttt tcccccactc tctctccacc tcctcctgcc ttccccaccc 61cgagtgcgga gccagagatc aaaagatgaa aaggcagtca ggtcttcagt agccaaaaaa 121caaaacaaac aaaaacaaaa aagccgaaat aaaagaaaaa gataataact cagttcttat 181ttgcacctac ttcagtggac actgaatttg gaaggtggag gattttgttt ttttctttta 241agatctgggc atcttttgaa tctacccttc aagtattaag agacagactg tgagcctagc 301agggcagatc ttgtccaccg tgtgtcttct tctgcacgag actttgaggc tgtcagagcg 361ctttttgcgt ggttgctccc gcaagtttcc ttctctggag cttcccgcag gtgggcagct 421agctgcagcg actaccgcat catcacagcc tgttgaactc ttctgagcaa gagaagggga 481ggcggggtaa gggaagtagg tggaagattc agccaagctc aaggatggaa gtgcagttag 541ggctgggaag ggtctaccct cggccgccgt ccaagaccta ccgaggagct ttccagaatc 601tgttccagag cgtgcgcgaa gtgatccaga acccgggccc caggcaccca gaggccgcga 661gcgcagcacc tcccggcgcc agtttgctgc tgctgcagca gcagcagcag cagcagcagc 721agcagcagca gcagcagcag cagcagcagc agcagcagca gcaagagact agccccaggc 781agcagcagca gcagcagggt gaggatggtt ctccccaagc ccatcgtaga ggccccacag 841gctacctggt cctggatgag gaacagcaac cttcacagcc gcagtcggcc ctggagtgcc 901accccgagag aggttgcgtc ccagagcctg gagccgccgt ggccgccagc aaggggctgc 961cgcagcagct gccagcacct ccggacgagg atgactcagc tgccccatcc acgttgtccc 1021tgctgggccc cactttcccc ggcttaagca gctgctccgc tgaccttaaa gacatcctga 1081gcgaggccag caccatgcaa ctccttcagc aacagcagca ggaagcagta tccgaaggca 1141gcagcagcgg gagagcgagg gaggcctcgg gggctcccac ttcctccaag gacaattact 1201tagggggcac ttcgaccatt tctgacaacg ccaaggagtt gtgtaaggca gtgtcggtgt 1261ccatgggcct gggtgtggag gcgttggagc atctgagtcc aggggaacag cttcgggggg 1321attgcatgta cgccccactt ttgggagttc cacccgctgt gcgtcccact ccttgtgccc 1381cattggccga atgcaaaggt tctctgctag acgacagcgc aggcaagagc actgaagata 1441ctgctgagta ttcccctttc aagggaggtt acaccaaagg gctagaaggc gagagcctag 1501gctgctctgg cagcgctgca gcagggagct ccgggacact tgaactgccg tctaccctgt 1561ctctctacaa gtccggagca ctggacgagg cagctgcgta ccagagtcgc gactactaca 1621actttccact ggctctggcc ggaccgccgc cccctccgcc gcctccccat ccccacgctc 1681gcatcaagct ggagaacccg ctggactacg gcagcgcctg ggcggctgcg gcggcgcagt 1741gccgctatgg ggacctggcg agcctgcatg gcgcgggtgc agcgggaccc ggttctgggt 1801caccctcagc cgccgcttcc tcatcctggc acactctctt cacagccgaa gaaggccagt 1861tgtatggacc gtgtggtggt ggtgggggtg gtggcggcgg cggcggcggc ggcggcggcg 1921gcggcggcgg cggcggcggc ggcgaggcgg gagctgtagc cccctacggc tacactcggc 1981cccctcaggg gctggcgggc caggaaagcg acttcaccgc acctgatgtg tggtaccctg 2041gcggcatggt gagcagagtg ccctatccca gtcccacttg tgtcaaaagc gaaatgggcc 2101cctggatgga tagctactcc ggaccttacg gggacatgcg aaatacccga agaaagagac 2161tctggaaact cattatcagg tctatcaact cttgtatttg ttctcccagg gaaacagaag 2221tacctgtgcg ccagcagaaa tgattgcact attgataaat tccgaaggaa aaattgtcca 2281tcttgtcgtc ttcggaaatg ttatgaagca gggatgactc tgggagaaaa attccgggtt 2341ggcaattgca agcatctcaa aatgaccaga ccctgaagaa aggctgactt gcctcattca 2401aaatgagggc tctagagggc tctagtggat agtctggaga aacctggcgt ctgaggctta 2461ggagcttagg tttttgctcc tcaacacaga ctttgacgtt ggggttgggg gctactctct 2521tgattgctga ctccctccag cgggaccaat agtgttttcc tacctcacag ggatgttgtg 2581aggacgggct gtagaagtaa tagtggttac cattcatgta gttgtgagta tcatgattat 2641tgtttcctgt aatgtggctt ggcattggca aagtgctttt tgattgttct tgatcacata 2701tgatgggggc caggcactga ctcaggcgga tgcagtgaag ctctggctca gtcgcttgct 2761tttcgtggtg tgctgccagg aagaaacttt gctgatggga ctcaaggtgt caccttggac 2821aagaagcaac tgtgtctgtc tgaggttcct gtggccatct ttatttgtgt attaggcaat 2881tcgtatttcc cccttaggtt ctagccttct ggatcccagc cagtgaccta gatcttagcc 2941tcaggccctg tcactgagct gaaggtagta gctgatccac agaagttcag taaacaagga 3001ccagatttct gcttctccag gagaagaagc cagccaaccc ctctcttcaa acacactgag 3061agactacagt ccgactttcc ctcttacatc tagccttact gtagccacac tccttgattg 3121ctctctcaca tcacatgctt ctcttcatca gttgtaagcc tctcattctt ctcccaagcc 3181agactcaaat attgtattga tgtcaaagaa gaatcactta gagtttggaa tatcttgttc 3241tctctctgct ccatagcttc catattgaca ccagtttctt tctagtggag aagtggagtc 3301tgtgaagcca gggaaacaca catgtgagag tcagaaggac tctccctgac ttgcctgggg 3361cctgtctttc ccaccttctc cagtctgtct aaacacacac acacacacac acacacacac 3421acacacgctc tctctctctc tcccccccca acacacacac actctctctc tctctcacac 3481acacacacat acacacacac ttctttctct ttcccctgac tcagcaacat tctggagaaa 3541agccaaggaa ggacttcagg aggggagttt cccccttctc agggcagaat tttaatctcc 3601agaccaacaa gaagttccct aatgtggatt gaaaggctaa tgaggtttat ttttaactac 3661tttctatttg tttgaatgtt gcatatttct actagtgaaa ttttccctta ataaagccat 3721taatacacc SEQ ID NO: 58 Mouse AR Amino Acid Sequence (NP_038504.1) 1mevqlglgrv yprppsktyr gafqnlfqsv reaiqnpgpr hpeaaniapp gaclqqrqet 61sprrrrrqqh tedgspqahi rgptgylale eeqqpsqqqa aseghpessc lpepgaatap 121gkglpqqppa ppdqddsaap stlsllgptf pglsscsadi kdilneagtm qllqqqqqqq 181ghqqghqghq qqqevisegs sarareatga pssskdsylg gnstisdsak elckavsvsm 241glgvealehl spgeqlrgdc myasllggpp avrptpcapl peckglplde gpgksteeta 301eyssfkggya kglegesigc sgsseagssg tleipsslsl yksgaldeaa ayqnrdyynf 361plalsgpphp pppthphari klenpldygs awaaaaaqcr ygdlgslhgg svagpstgsp 421pattssswht lftaeegqly gpgggggsss psdagpvapy gytrppqglt sqesdysase 481vwypggvvnr vpypspncvk semgpwmeny sgpygdmrld strdhvlpid yyfppqktcl 541icgdeasgch ygaltcgsck vffkraaegk qkylcasrnd ctidkfrrkn cpscrlrkcy 601eagmtlgark lkklgnlklq eegensnags ptedpsqkmt vshiegyecq piflnvleai 661epgvvcaghd nnqpdsfaal lsslnelger qlvhvvkwak alpgfrnlhv ddqmaviqys 721wmglmvfamg wrsftnvnsr mlyfapdivf neyrmhksrm ysqcvrmrhl sqefgwlqit 781pqeflcmkal llfsiipvdg lknqkffdel rmnyikeldr iiackrknpt scsrrfyqlt 841klldsvqpia relhqftfdl likshmvsvd fpemmaeiis vqvpkilsgk vkpiyfhtqSEQ ID NO: 59 Mouse AR transcript cDNA sequence (NM_013476.4;CDS: 1026 . . . 3725) 1cagcgccccc tcggagatcc ctaggagcca gcctgctggg agaaccagag ggtccggagc 61aaacctggag gctgagaggg catcagaggg gaaaagactg agctagccac tccagtgcca 121tacagaagct taagggacgc accacgccag ccccagccca gcgacagcca acgcctgttg 181cagagcggcg gcttcgaagc cgccgcccag gagctgccct ttcctcttcg gtgaagtttc 241taaaagctgc gggagactca gaggaagcaa ggaaagtgtc cggtaggact acggctgcct 301ttgtcctctt cccctctacc cttaccccct cctgggtccc ctctccagga gctgactagg 361caggctttct ggccaaccct ctcccctaca cccccagctc tgccagccag tttgcacaga 421ggtaaactcc ctttggctga gagtagggga gcttgttgca cattgcaagg aaggcttttg 481ggagcccaga gactgaggag caacagcacg cccaggagag tccctggttc caggttctcg 541cccctgcacc tcctcctgcc cgcccctcac cctgtgtgtg gtgttagaaa tgaaaagatg 601aaaaggcagc tagggtttca gtagtcgaaa gcaaaacaaa agctaaaaga aaacaaaaag 661aaaatagccc agttcttatt tgcacctgct tcagtggact ttgaatttgg aaggcagagg 721atttcccctt ttccctcccg tcaaggtttg agcatctttt aatctgttct tcaagtattt 781agagacaaac tgtgtaagta gcagggcaga tcctgtcttg cgcgtgcctt cctttactgg 841agactttgag gttatctggg cactcccccc acccaccccc cctcctgcaa gttttcttcc 901ccggagcttc ccgcaggtgg gcagctagct gcagatacta catcatcagt caggagaact 961cttcagagca agagacgagg aggcaggata agggaattcg gtggaagcta cagacaagct 1021caaggatgga ggtgcagtta gggctgggaa gggtctaccc acggccccca tccaagacct 1081atcgaggagc gttccagaat ctgttccaga gcgtgcgcga agcgatccag aacccgggcc 1141ccaggcaccc tgaggccgct aacatagcac ctcccggcgc ctgtttacag cagaggcagg 1201agactagccc ccggcggcgg cggcggcagc agcacactga ggatggttct cctcaagccc 1261acatcagagg ccccacaggc tacctggccc tggaggagga acagcagcct tcacagcagc 1321aggcagcctc cqaqqqccac cctgagagca gctgcctccc cgagcctggg qcqqccaccq 1381ctcctggcaa ggggctgccg cagcagccac cagctcctcc agatcaggat gactcagctg 1441ccccatccac gttgtccctg ctgggcccca ctttcccagg cttaagcagc tgctccgccg 1501acattaaaga cattttgaac gaggccggca ccatgcaact tcttcagcag cagcaacaac 1561agcagcagca ccaacagcag caccaacagc accaacagca gcaggaggta atctccgaag 1621gcagcagcgc aagagccagg gaggccacgg gggctccctc ttcctccaag gatagttacc 1681tagggggcaa ttcaaccata tctgacagtg ccaaggagtt gtgtaaagca gtgtctgtgt 1741ccatgggatt gggtgtggaa gcattggaac atctgagtcc aggggaacag cttcggggag 1801actgcatgta cgcgtcgctc ctgggaggtc cacccgcggt gcgtcccact ccttgtgcgc 1861cgctgcccga atgcaaaggt cttcccctgg acgaaggccc aggcaaaagc actgaagaga 1921ctgctgagta ttcctctttc aagggaggtt acgccaaagg attggaaggt gagagcttgg 1981ggtgctctgg cagcagtgaa gcaggtagct ctgggacact tgagatcccg tcctctctgt 2041ctctgtataa atctggagca ctagacgagg cagcagcata ccagaatcgc gactactaca 2101actttccgct ggctctgtcc gggccgccgc accccccgcc ccctacccat ccacacgccc 2161gtatcaagct ggagaaccca ttggactacg gcagcgcctg ggctgcggcg gcagcgcaat 2221gccgctatgg ggacttgggt agtctacatg gagggagtgt agccgggccc agcactggat 2281cgcccccagc caccacctct tcttcctggc atactctctt cacagctgaa gaaggccaat 2341tatatgggcc aggaggcggg ggcggcagca gcagcccaag cgatgccggg cctgtagccc 2401cctatggcta cactcggccc cctcaggggc tgacaagcca ggagagtgac tactctgcct 2461ccgaagtgtg gtatcctggt ggagttgtga acagagtacc ctatcccagt cccaattgtg 2521tcaaaagtga aatgggacct tggatggaga actactccgg accttatggg gacatgcgtt 2581tggacagtac cagggaccat gttttaccca tcgactatta ctttccaccc cagaagacct 2641gcctgatctg tggagatgaa gcttctggct gtcactacgg agctctcact tgtggcagct 2701gcaaggtctt cttcaaaaga gccgctgaag ggaaacagaa gtatctatgt gccagcagaa 2761acgattgtac cattgataaa tttcggagga aaaattgccc atcttgtcgt ctccggaaat 2821gttatgaagc agggatgact ctgggagctc gtaagctgaa gaaacttgga aatctaaaac 2881tacaggagga aggagaaaac tccaatgctg gcagccccac tgaggaccca tcccagaaga 2941tgactgtatc acacattgaa ggctatgaat gtcagcctat ctttcttaac gtcctggaag 3001ccattgagcc aggagtggtg tgtgccggac atgacaacaa ccaaccagat tcctttgctg 3061ccttgttatc tagcctcaat gagcttggag agaggcagct tgtgcatgtg gtcaagtggg 3121ccaaggcctt gcctggcttc cgcaacttgc atgtggatga ccagatggcg gtcattcagt 3181attcctggat gggactgatg gtatttgcca tgggttggcg gtccttcact aatgtcaact 3241ccaggatgct ctactttgca cctgacttgg ttttcaatga gtaccgcatg cacaagtctc 3301ggatgtacag ccagtgtgtg aggatgaggc acctgtctca agagtttgga tggctccaaa 3361taacccccca ggaattcctg tgcatgaaag cactgctgct cttcagcatt attccagtgg 3421atgggctgaa aaatcaaaaa ttctttgatg aacttcgaat gaactacatc aaggaactcg 3481atcgcatcat tgcatgcaaa agaaagaatc ccacatcctg ctcaaggcgc ttctaccagc 3541tcaccaagct cctggattct gtgcagccta ttgcaagaga gctgcatcag ttcacttttg 3601acctgctaat caagtcccat atggtgagcg tggactttcc tgaaatgatg gcagagatca 3661tctctgtgca agtgcccaag atcctttctg ggaaagtcaa gcccatctat ttccacacac 3721agtgaagatt tggaaaccct aatacccaaa acccaccttg ttccctttcc agatgtcttc 3781tgcctgttat ataactctgc actacttctc tgcagtgcct tgggggaaat tcctctactg 3841atgtacagtc tgtcgtgaac aggttcctca gttctatttc ctgggcttct ccttcttttt 3901ttttcttctt ccctccctct ttcaccctcc catggcacat tttgaatctg ctgcgtattg 3961tggctcctgc ctttgttttg atttctgttg tatttctttg aatctgtgat gatcctcttg 4021tggcccagtg tcaattgtgc ttgtttatag cactgtgctg tgtgccaacc aagcaaatgt 4081ttactcacct tatgccatgg caaatttaga gagctataag tatctggaga agaaacaaac 4141agagagaata aaaagcaaaa acaaaaccaa aaaataaaaa aaacacaaac aaaaaacaaa 4201accaacaaac aaaacatgct aggtttgttt cttcgtggta tacaaataaa cacataggat 4261tcccaaagaa gccgacagtg actagaagaa agtaaaaaat tacaaatcca cgaggagtca 4321ctgtttttgt tcatcctgtt tctctgtggg aaacttcagt tgttgttaat ggctattgcc 4381attaaagagc aggttgaccc caaagcttta ctgatagggt agagagaaaa gaggacaagg 4441agggcagatg gataaccatt acctccccac agcctttgtc cctgagtcct agagtgctca 4501gttgcagtgt agttccttgt actgaaatgt gcttcttgtt tgaaaacttg tctgcatgtg 4561aatgcctctt ccttccaatc cttttctctc ttaacctctg cttccaccct caattgactt 4621tcaatagctt ttctcagagc tttgtactat atgctctctt tagccaaaac ttggccactt 4681tcactgaagt tatgtcagtg agaagaaagt ggaaaggtct gactctttgg aaggctctat 4741tcagatttat gttcatattt ccatgtgtga gccatagcgg agctttgtga ctggagtcag 4801aggaaaagga agtgatggct tagccattct cccattagag atagtgaatg atgatgccat 4861agtgcaatca tcctttcctc tgcttttaaa ggacctagag accccatgca gccacattct 4921ccctgcacaa gtcttcagtg ttcagtggcc ctgaacttca ccaaaatgca tttaagccaa 4981ggtggtaaag cttgtacact tctttggacg tgtttgtaga cactgctaag atctccctct 5041caccaccacc acaaaggcta gcaggccagc agccacagca tctatgttta gatgttaata 5101gcataaaaga catctcactc aatgtctttc atcaacagta aatttctgga gcccttagaa 5161aaattggaaa gaaagcatca aagggaccag acaaaatggg catcttgccc ttgtcctcca 5221gagacaatat attcctccca agtggagaaa tgtcaatttc ctcctcagaa caattaaagg 5281ggctacccag accatggtgg aagagaaaac taagtaaccc agctgagaaa aatgaagaca 5341ctagaaccag aaagcacagg actttttcct ttccatccag catacccatt ggcagaaata 5401atggaaggaa aagagaaggc cagaagaaaa tacagactgc tgaagtcttc agaggcaaag 5461tctaaagcca gatgaatacc atctggctag atgggcatca gtttgctcat cctcctctat 5521tgccattgct gggctgactt tggccaaagt tacttcgaat ctccaccata gttgtcccct 5581ctcagtcaga gggtgcagga ccactgaaac attctatcca ccgtgactct cattggacag 5641atctggccgg tgtggctaca aatagactgc acccataaac tcagggcaag ccctgggtca 5701ctggtttcat gtagtctgtt gacagccttc tttactgtgg actctgttcc tcaaccttga 5761gtgcaggagg aatgcacatc tacttttgcc tttgtatcat tcctcctcac tcagctcttc 5821acctccctgc agaccttaag aaatcagggg ccagctgcca agctgactct tttggttggt 5881actatgttaa ctgaaaaggt gatttccgaa ggacaggttt tcttccctga tttctttgtt 5941gctattaata gcaaaaacaa acttgcaaaa caacttcttt aacaaggaag ggaggatata 6001tacaatgggt gatatggtaa tccaaccctg cttgacaaaa actgaagctg acaggttaca 6061tttaaaaaca aaacaaaaca aaacgggaca gtttctgatt tgctttgtga caacaccatc 6121tggcttatgt acaggagctc tcttagctgt tccttaaaca gaaaaaaaat cattactcct 6181tttagttaaa tttggttaca ttttaatagt ttctttacat ctattctgaa gcaatttttg 6241tcttctgtgg tacatggatt ttattataac attctaatat ttgtctttgt aaatactaga 6301gactctttga tccatttctc taggaagttt ttcatcttat ggagttctga atcatgactt 6361ttatctttat gaatgtatat gctttttact tgcaaaagcc aaaaagagtg aaacagcagt 6421gcaattaaag caacaccaac taaactccaa atttccaagt gacaatatta gagaaaaaca 6481gcatacacat ggctttatgc ctactgcttc tgcggtgggg tttgggtgcg caatggaaac 6541tgtagcttgg ctgtgttctc ccacacaagt gaagaagaga ttggtttttg cttttttgga 6601ttttgtgttt cttttctgtt ttgttttgtt ttgttttgtt ttgctttgct ttctttggcc 6661atcaatgttc caactaatat gattggcgga gcacgtgctc tgctcagtag agtgaatgtt 6721gctggtgcac tatgctcacc tgtgaacggc tggccatttc tccattcata tggttaagat 6781ggaagatgag gatcacttac cagagaagtc aaggtgatca tctccaaaga ggtttacagt 6841gcttggtagg aatggaaaat gaggacaaga aaaagaggag aaccatggag aaggcccaac 6901tgggcaggac agcagccagc tgccaaagtc acgaactctg ggattcaaga agagtcgtgt 6961agtgctttca actctcatcc gcaggcagct cactgtgtgt ggactctgag ctgacacggg 7021agttggcttc tttgttccat agattttcta tgccacaggc aatattattg ttcttggaaa 7081gttcattatt tttttaaatt accttactct cagaaaggga tttttttgaa ggattctgtc 7141atatatcttt ggaaaacaga aaatcagtaa tatgtatatt tttatgtatg ttcactggca 7201ctaaaaaaaa aaaaaaaaag aaaagaaaaa aaagagaaaa aaaaaagctt cactctgtcc 7261tttgggtagt tgctgaggtt aattgtccag gttgagaaat gtgcttctgc taacatcctt 7321ctctgtccac actctatttc taagtacata taggcatata taggaagata tattcaacac 7381actttaagaa aaaagtatgt ccaccatcca catgataacc acaatgatac tccacaaatt 7441acatgacttt aagcttcaag caacttctaa ctgattcatt catttatagc cttgccctct 7501tctttccctt aaatttggcc cagcacaaag acccaagcca cccttatacc tccctaagac 7561ttaagccagc accagacttc agaaggtttt ctgaagacaa ctgacttgct atccctgcat 7621gaccctagca tggtcctgca aacacaagag actaattata attctcctcc actaattgcc 7681tgggtcacag gtcattgggc caaggccatg attcttatgc ttacgaacca ctaatgctaa 7741cctactagat taaatcctga actgaaagtt aaaagaagcc atttagcatg tgaaacttct 7801tggagtaaga agtttctgtc ccggctgcct ttgcaaacag gtttgctttc accacttatc 7861tccttgaaaa tctttgaagg cctttttttt ttaagtagaa aaggagatga aagcattata 7921ttatgtaacc aaagattata ttgtatctaa gataccaaat tttttaaggg cagggaagga 7981gcaagcatta gtgcctcttt ggtaaattat ccaaagacag actgaaggac ttttctgatg 8041attgacttag aagactttgt ggggaggggt tgtctcacaa tatacatatt tagaagtgtt 8101gagaataatt tggggggaaa tgggattata gtgtccttca ctaactgatt ttataagcag 8161aactagcttt cctttttttt ttttttaaag tagttacaaa gcaaattctt aaagctccat 8221ctttgcatgg ttagaaatgg agctggtctt ggccactgtg tttactagtg cccatgttag 8281cttatttgaa gatgtgaagc ccttgataag aaggggtaca tttaaaggat tagatttttg 8341cactagaagg agggcaggca gaaaccctca tttctgccca gtttggacag cacaaaaagt 8401tctctgcagt ttaaggcaga aagttgaaat atattgtaaa tgagtatttg tatccatgtt 8461tcaaaactga attctatata tagatgtaat gtgttctgat agctttacct ttctctgcac 8521ctttatattt ggttccaggt catatctgat gccatgtact tgtaagagag gttgcagtta 8581catttttgga tgctctctca gaatggataa gacacctgga ttgatcagat aactgagatc 8641tcttcccttc ttgggcctgg tgttgaggcc ttgcaaaggg gtggaagagg aaagggtagg 8701gtacatgatg tattgcactt tactagctta agacggatga atgtggaaag ggtggtgaaa 8761tttcattgaa aatgcctagg aattgcaata gggagaaatc cagatgtggg gccaggtgcc 8821cacccaaagg actggccagc agcctcttca tgggatctga ggcattggga aaaggaaggc 8881tatttccttg gttttcacca tccttgttag agaagggcag ttgcctggtc ttgggaacct 8941ggagcaaacg ctccttctgt cacatcaatt ctttcccctg caattgaggt gctcttgcta 9001ctgggtgtcc gtgtgctcta attctggttc tggatatgtt ctgtaaagat tttgataatt 9061gctaatgtat ttttctctgt taaaaatttg ttagtgtgtt agaagtcata tctctgtagg 9121tacagatcct ttgctaccca tgagtagagg gatttttttt cttcaattaa gagtttgacc 9181ctggggtctg ttgcccagag cccatccaga aaaaaaaatc cacatttgtc acaatttttc 9241tgaaatttca gtcaaggtaa cagatcgctg ggagttctct ttaccccccc aaaaaagcag 9301ataattgaat ttagcaggtg gtgttttaga gcaaaaaaca aaacagcctt tgacccagct 9361ttaatatgac ccaatttaat ctggccagga agcaggtaat gtgtattaat tggcttccaa 9421tcctggttga gtgtagcaag gttctacttt gtttcctagt tccttttgtt acatggcctt 9481tcacagaaag gattgactgg gtttgcagta tatcttatgg ccttagcacc tattgctaac 9541tgtcctgaag ggaattgcct atggggttgt cctataagcc acttctatca ttaaaagcag 9601ccaccaatgg aatctcccag gtttgaaaaa aaaaaaaaaa aacagatggt cctttaccat 9661tcattgacac acatccctgc tttcctgtag acagattgac tggacattga ttagggaata 9721catggcaaat gacatgctta cactaccctg gagattaatt tggcagtagg agggaataga 9781caatgtaacc aagaatgtaa tgtaattctt atagagataa gaattaaatc tggatgtgga 9841gagagcaaag agagaaagca ttcaattttt ttttcaaaag aaaccaattt attttgcttg 9901aaacttcttt cgctggggct tcagttctca cagcggctct tggtctccac tgggcagcag 9961gaccagcccc aagcgctagt gttctgttct ctttttgtaa tcttggaatc ttttgttgct 10021ctaaatacaa ttaaaaatgc cagaaacttc tttgttggaa tac* Included in Tables 1A and 1B are orthologs of the proteins, as well aspolypeptide molecules comprising an amino acid sequence having at least80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%,94%, 95%, 96%, 97%, 98%, 99%, 99.5%, or more identity across their fulllength with an amino acid sequence of any SEQ ID NO listed in Tables 1Aand 1B, or a portion thereof. Such polypeptides can have a function ofthe full-length polypeptide as described further herein.

TABLE 1C Methylation status Nearest Start End (NE vs Distance PromoterChr (hg19) (hg19) Adeno) Annotation to TSS ID chr1 241206098 241206097hyper intron −89475 NR_036069 (NM_001282773, intron 3 of 15) chr1847258089 47258088 hyper Intergenic 82163 NM_006111 chr21 3254632632546325 hyper intron −135530 NM_001099219 (NM_003253, intron 16 of 28)chr5 1548487 1548486 hyper Intergenic −24410 NM_024830 chr5 7114689471146893 hyper Intergenic 131903 NM_004291 chr5 142194123 142194122hyper intron 43830 NM_015071 (NM_015071, intron 1 of 22) chr7 77990187799017 hyper intron −40779 NM_002947 (NM_001302350, intron 3 of 4) chr7127841628 127841627 hyper Intergenic −6298 NR_029596 chr8 5349956053499559 hyper Intergenic −21538 NM_207413 chr8 73479990 73479989 hyperexon 30363 NM_004770 (NM_004770, exon 2 of 3) chr8 73849054 73849053hyper exon −72044 NM_003218 (NM_004770, exon 3 of 3) chr8 140727998140727997 hyper Intergenic −12698 NR_104210 chr8 141994084 141994083hyper intron 17329 NM_001199649 (NM_153831, intron 1 of 31) chr8142367954 142367953 hyper exon 9412 NM_005293 (NM_005293, exon 2 of 2)chr8 143395944 143395943 hyper intron 88667 NM_145003 (NM_001291931,intron 6 of 10) chr9 36748433 36748432 hyper Intergenic 75164 NR_039686chr9 38437314 38437313 hyper Intergenic −12869 NM_001007563 chr993792388 93792387 hyper Intergenic 45027 NR_033912 chr9 133769512133769511 hyper intron 2688 NM_198180 (NM_198180, intron 2 of 2) chr9138719304 138719303 hyper exon 79702 NM_015447 (NM_015447, exon 8 of 17)Gene Gene Chr Name Gene Alias Gene Description Type chr1 MIR3123mir-3123 microRNA 3123 ncRNA chr18 ACAA2 DSAEC acetyl-CoA protein-acyltransferase 2 coding chr21 KRTAP19-8 keratin associated protein-protein 19-8 coding chr5 LPCAT1 AYTL2|PFAAP3|lpcatlysophosphatidylcholine protein- acyltransferase 1 coding chr5 CARTPTCART CART protein- prepropeptide coding chr5 ARHGAP26 GRAF|GRAF1|OPHN1L|Rho GTPase protein- OPHN1L1 activating protein coding 26 chr7 RPA3 REPA3replication protein protein- A3 coding chr7 MIR129-1 MIR-129b|MIRN129-1|microRNA 129-1 ncRNA mir-129-1 chr8 FAM150A UNQ9433 family with protein-sequence coding similarity 150, member A chr8 KCNB2 KV2.2 potassiumchannel, protein- voltage gated Shab coding related subfamily B, member2 chr8 TERFI PIN2|TRBF1|TRF|TRF1| telomeric repeat protein-hTRF1-AS|t-TRF1 binding factor coding (NIMA- interacting) 1 chr8 KCNK9K2p9.1|KT3.2|TASK-3| potassium channel, protein- TASK3 two pore domaincoding subfamily K, member 9 chr8 PTK2 FADK|FAK|FAK1|FRNK| proteintyrosine protein- PPP1R71|p125FAK|pp125FAK kinase 2 coding chr8 GPR20 —G protein-coupled protein- receptor 20 coding chr8 TSNARE1 — t-SNAREdomain protein- containing 1 coding chr9 MIR4475 — microRNA 4475 ncRNAchr9 IGFBPL1 IGFBP-RP4|IGFBPRP4|bA113024.1 insulin like growth protein-factor binding coding protein-like 1 chr9 LOC100129316 — uncharacterizedncRNA LOC100129316 chr9 QRFP 26RFa|P518 pyroglutamylated protein-RFamide peptide coding chr9 CAMSAP1 PRO2405|bA100C15.1 calmodulinprotein- regulated spectrin- coding associated protein 1

TABLE 1D Methylation status Nearest Start End (NE vs Distance PromoterChr (hg19) (hg19) Adeno) Annotation to TSS ID chr1 202039153 202039152hypo Intergenic −52877 NM_004767 chr14 100039425 100039424 hypo intron31303 NM_001144995 (NM_001144995, intron 1 of 5) chr18 8660098 8660097hypo Intergenic 47522 NR_120598 chr18 14917016 14917015 hypo Intergenic−29251 NR_104164 chr18 25442246 25442245 hypo Intergenic 174304NM_001308176 chr2 89530057 89530056 hypo Intergenic 418172 NR_039635chr20 20421462 20421461 hypo intron 72696 NM_002196 (NM_020343, intron37 of 39) chr20 21563921 21563920 hypo intron 13258 NR_109880(NR_109880, intron 1 of 3) chr21 46885392 46885391 hypo intron 9967NM_130444 (NM_130444, intron 1 of 41) chr3 193490472 193490471 hypoIntergenic −145350 NR_046634 chr5 36521979 36521978 hypo Intergenic−84479 NM_001289940 chr5 39390555 39390554 hypo exon −25899 NM_001737(NM_001343, exon 5 of 15) chr5 168573593 168573592 hypo intron 117106NR_030311 (NM_001271946, intron 4 of 35) chr7 2006579 2006578 hypointron −26392 NM_001304525 (NM_001304523, intron 14 of 17) chr7129912398 129912397 hypo intron 5694 NM_001869 (NM_001869, intron 4 of10) chr8 61990390 61990389 hypo Intergenic −110082 NR_034003 chr869087227 69087226 hypo intron −155731 NM_052958 (NM_024870, intron 35 of39) chr8 133070961 133070960 hypo intron 667 NM_001080399 (NM_001080399,intron 1 of 13) chr8 141458926 141458925 hypo intron 8936 NM_001160372(NM_031466, intron 2 of 22) chr9 134913164 134913163 hypo intron 42111NM_001253881 (NM_001253881, intron 2 of 6) Gene Gene Chr Name Gene AliasGene Description Type chr1 GPR37L1 ET(B)R-LP-2|ETBR-LP-2 Gprotein-coupled protein- receptor 37 like 1 coding chr14 CCDC85C —coiled-coil domain protein- containing 85 C coding chr18 GACAT2MTCL1-AS1|MTCL1AS1 gastric cancer associated ncRNA transcript 2(non-protein coding) chr18 LINC01443 — long intergenic non- ncRNAprotein coding RNA 1443 chr18 CDH2 CD325|CDHN|CDw325|NCAD cadherin 2,type 1, N- protein- cadherin (neuronal) coding chr2 MIR4436A mir-4436amicroRNA 4436a ncRNA chr20 INSM1 IA-1|IA1 insulinoma-associated 1protein- coding chr20 LOCI01929625 — uncharacterized ncRNA LOC101929625chr21 COL18A1 KNO|KNO1|KS collagen type XVIII, protein- alpha 1 codingchr3 OPA1-AS1 — OPA1 antisense RNA 1 ncRNA chr5 SLC1A3EA6|EAAT1|GLAST|GLAST1 solute carrier family 1 protein- (glial highaffinity coding glutamate transporter), member 3 chr5 C9 ARMD15|C9Dcomplement component protein- 9 coding chr5 MIR585MIRN585|hsa-mir-585|mir-585 microRNA 585 ncRNA chr7 MAD1L1MAD1|PIG9|TP53I9|TXBP181 MAD1 mitotic arrest protein- deficient-like 1(yeast) coding chr7 CPA2 carboxypeptidase A2 protein- (pancreatic)coding chr8 LOC100130298 hCG1816373-like ncRNA chr8 C8orf34 VEST-1|VEST1chromosome 8 open protein- reading frame 34 coding chr8 OC90 PLA2Lotoconin 90 protein- coding chr8 TRAPPC9 IBP|IKBKBBP|MRT13|NIBP|trafficking protein protein- T1|TRS120 particle complex 9 coding chr9MED27 CRAP34|CRSP34|CRSP8|TRAP37 mediator complex protein- subunit 27coding

II. Subjects

In one embodiment, the subject for whom predicted likelihood of havingcastration-resistant neuroendocrine prosate cancer (CRPC-NE) or at riskfor developing CRPC-NE is determined, is a mammal (e.g., mouse, rat,primate, non-human mammal, domestic animal, such as a dog, cat, cow,horse, and the like), and is preferably a human. In another embodiment,the subject is an animal model of prostate cancer. For example, theanimal model can be an orthotopic xenograft animal model of ahuman-derived prostate cancer.

In another embodiment of the methods of the present invention, thesubject is afflicted with castration-resistant prostate cancer (CRPC).In still another embodiment, the subject is resistant to an androgenreceptor (AR)-directed therapy.

In another embodiment of the methods of the present invention, thesubject has not undergone treatment, such as chemotherapy, radiationtherapy, targeted therapy, and/or immunotherapies. In still anotherembodiment, the subject has undergone treatment, such as chemotherapy,radiation therapy, targeted therapy, and/or immunotherapies.

In certain embodiments, the subject has had surgery to remove cancerousor precancerous tissue. In other embodiments, the cancerous tissue hasnot been removed, e.g., the cancerous tissue may be located in aninoperable region of the body, such as in a tissue that is essential forlife, or in a region where a surgical procedure would cause considerablerisk of harm to the patient.

III. Sample Collection, Preparation and Separation

In some embodiments, genomic (e.g., deletion, gain, or mutation) and/orepigenomic (e.g., hypermethylation or hypomethylation) alterations ofthe biomarkers in a sample of interest, such as from a subject, iscompared to a control (standard) sample. The sample from the subject istypically from a diseased tissue, such as cancer cells or tissues. Incertain embodiments, the sample is cell-free DNA (cfDNA) or circulatingtumor DNA (ctDNA). Reagents and protocols for obtaining and analyzingcfDNA and ctDNA, such as circulating in the blood stream or othertissue, are commercially available as described in the Examples and alsowell-known in the art (see, for example, Anker et al. (1999) Cancer andMetastasis Rev. 18:65-73; Wua et al. (2002) Clin. Chim. Acta 321:77-87;Fiegl et al. (2005) Cancer Res. 15:1141; Pathak et al. (2006) Clin.Chem. 52:1833-1842; Schwarzenbach et al. (2009) Clin. Cancer Res.15:1032; Schwarzenbach et al. (2011) Nat. Rev. Cancer 11:426-437).

The control sample can be from the same subject or from a differentsubject. The control sample is typically a normal, non-diseased sample.However, in some embodiments, such as for staging of disease or forevaluating the efficacy of treatment, the control sample can be from adiseased tissue (e.g., from a subject with castration resistant prostateadenocarcinoma (CRPC-Adeno)). The control sample can be a combination ofsamples from several different subjects. In some embodiments, thegenomic and/or epigenomic alterations of the biomarkers from a subjectis compared to a pre-determined level. This pre-determined level istypically obtained from normal samples. As described herein, a“pre-determined” biomarker genomic and/or epigenomic alteration(s) maybe a biomarker genomic and/or epigenomic alteration(s) used to, by wayof example only, diagnose the subject (e.g., based on the present orabsence of specific genomic and/or epigenomic alteration(s) of thebiomarkers, evaluate whether a subject is afflicted withcastration-resistant neuroendocrine prosate cancer (CRPC-NE) or at riskfor developing CRPC-NE). A pre-determined biomarker genomic and/orepigenomic alteration(s) may be determined in populations of patientswith or without cancer. The pre-determined biomarker genomic and/orepigenomic alteration(s) can be a single number, equally applicable toevery patient, or the pre-determined biomarker genomic and/or epigenomicalteration(s) can vary according to specific subpopulations of patients.Age, weight, height, and other factors of a subject may affect thepre-determined biomarker genomic and/or epigenomic alteration(s) of theindividual. Furthermore, the pre-determined biomarker genomic and/orepigenomic alteration(s) can be determined for each subjectindividually. In one embodiment, the genomic and/or epigenomicalteration(s) determined and/or compared in a method described hereinare based on absolute measurements.

In another embodiment, the amounts determined and/or compared in amethod described herein are based on relative measurements, such asratios (e.g., biomarker copy numbers, methylation level, and/ormutations before a treatment vs. after a treatment, such biomarkermeasurements relative to a spiked or man-made control, such biomarkermeasurements relative to the expression of a housekeeping gene, and thelike). For example, the relative analysis can be based on the ratio ofpre-treatment biomarker measurement as compared to post-treatmentbiomarker measurement. Pre-treatment biomarker measurement can be madeat any time prior to initiation of anti-cancer therapy. Post-treatmentbiomarker measurement can be made at any time after initiation ofanti-cancer therapy. In some embodiments, post-treatment biomarkermeasurements are made 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15,16, 17, 18, 19, 20 weeks or more after initiation of anti-cancertherapy, and even longer toward indefinitely for continued monitoring.Treatment can comprise anti-cancer therapy, such as a platum-basedchemotherapy alone or in combination with other anti-cancer agents, suchas with AR-targeted therapies and/or immunotherapies.

The pre-determined biomarker genomic and/or epigenomic alteration(s) canbe any suitable standard. For example, the pre-determined biomarkergenomic and/or epigenomic alteration(s) can be obtained from the same ora different human for whom a patient selection is being assessed. In oneembodiment, the pre-determined biomarker genomic and/or epigenomicalteration(s) can be obtained from a previous assessment of the samepatient. In such a manner, the progress of the selection of the patientcan be monitored over time. In addition, the control can be obtainedfrom an assessment of another human or multiple humans, e.g., selectedgroups of humans, if the subject is a human. In such a manner, theextent of the selection of the human for whom selection is beingassessed can be compared to suitable other humans, e.g., other humanswho are in a similar situation to the human of interest, such as thosesuffering from similar or the same condition(s) and/or of the sameethnic group.

In some embodiments of the present invention the change of biomarkergenomic and/or epigenomic alteration(s) from the pre-determined level isabout 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 1.5, 2.0, 2.5,3.0, 3.5, 4.0, 4.5, or 5.0 fold or greater, or any range in between,inclusive. Such cutoff values apply equally when the measurement isbased on relative changes, such as based on the ratio of pre-treatmentbiomarker measurement as compared to post-treatment biomarkermeasurement.

Biological samples can be collected from a variety of sources from apatient including a body fluid sample, cell sample, or a tissue samplecomprising nucleic acids and/or proteins. “Body fluids” refer to fluidsthat are excreted or secreted from the body as well as fluids that arenormally not (e.g., amniotic fluid, aqueous humor, bile, blood and bloodplasma, cerebrospinal fluid, cerumen and earwax, cowper's fluid orpre-ejaculatory fluid, chyle, chyme, stool, female ejaculate,interstitial fluid, intracellular fluid, lymph, menses, breast milk,mucus, pleural fluid, pus, saliva, sebum, semen, serum, sweat, synovialfluid, tears, urine, vaginal lubrication, vitreous humor, vomit). In apreferred embodiment, the subject and/or control sample is selected fromthe group consisting of cells, cell lines, histological slides, paraffinembedded tissues, biopsies, whole blood, nipple aspirate, serum, plasma,buccal scrape, saliva, cerebrospinal fluid, urine, stool, and bonemarrow. In one embodiment, the sample is serum, plasma, or urine. Inanother embodiment, the sample is serum.

The samples can be collected from individuals repeatedly over alongitudinal period of time (e.g., once or more on the order of days,weeks, months, annually, biannually, etc.). Obtaining numerous samplesfrom an individual over a period of time can be used to verify resultsfrom earlier detections and/or to identify an alteration in biologicalpattern as a result of, for example, disease progression, drugtreatment, etc. For example, subject samples can be taken and monitoredevery month, every two months, or combinations of one, two, or threemonth intervals according to the present invention. In addition, thebiomarker amount and/or activity measurements of the subject obtainedover time can be conveniently compared with each other, as well as withthose of normal controls during the monitoring period, thereby providingthe subject's own values, as an internal, or personal, control forlong-term monitoring.

Sample preparation and separation can involve any of the procedures,depending on the type of sample collected and/or analysis of biomarkermeasurement(s). Such procedures include, by way of example only,concentration, dilution, adjustment of pH, removal of high abundancepolypeptides (e.g., albumin, gamma globulin, and transferrin, etc.),addition of preservatives and calibrants, addition of proteaseinhibitors, addition of denaturants, desalting of samples, concentrationof sample proteins, extraction and purification of lipids.

The sample preparation can also isolate molecules that are bound innon-covalent complexes to other protein (e.g., carrier proteins). Thisprocess may isolate those molecules bound to a specific carrier protein(e.g., albumin), or use a more general process, such as the release ofbound molecules from all carrier proteins via protein denaturation, forexample using an acid, followed by removal of the carrier proteins.

Removal of undesired proteins (e.g., high abundance, uninformative, orundetectable proteins) from a sample can be achieved using high affinityreagents, high molecular weight filters, ultracentrifugation and/orelectrodialysis. High affinity reagents include antibodies or otherreagents (e.g., aptamers) that selectively bind to high abundanceproteins. Sample preparation could also include ion exchangechromatography, metal ion affinity chromatography, gel filtration,hydrophobic chromatography, chromatofocusing, adsorption chromatography,isoelectric focusing and related techniques. Molecular weight filtersinclude membranes that separate molecules on the basis of size andmolecular weight. Such filters may further employ reverse osmosis,nanofiltration, ultrafiltration and microfiltration.

Ultracentrifugation is a method for removing undesired polypeptides froma sample. Ultracentrifugation is the centrifugation of a sample at about15,000-60,000 rpm while monitoring with an optical system thesedimentation (or lack thereof) of particles. Electrodialysis is aprocedure which uses an electromembrane or semipermable membrane in aprocess in which ions are transported through semi-permeable membranesfrom one solution to another under the influence of a potentialgradient. Since the membranes used in electrodialysis may have theability to selectively transport ions having positive or negativecharge, reject ions of the opposite charge, or to allow species tomigrate through a semipermable membrane based on size and charge, itrenders electrodialysis useful for concentration, removal, or separationof electrolytes.

Separation and purification in the present invention may include anyprocedure known in the art, such as capillary electrophoresis (e.g., incapillary or on-chip) or chromatography (e.g., in capillary, column oron a chip). Electrophoresis is a method which can be used to separateionic molecules under the influence of an electric field.Electrophoresis can be conducted in a gel, capillary, or in amicrochannel on a chip. Examples of gels used for electrophoresisinclude starch, acrylamide, polyethylene oxides, agarose, orcombinations thereof. A gel can be modified by its cross-linking,addition of detergents, or denaturants, immobilization of enzymes orantibodies (affinity electrophoresis) or substrates (zymography) andincorporation of a pH gradient. Examples of capillaries used forelectrophoresis include capillaries that interface with an electrospray.

Capillary electrophoresis (CE) is preferred for separating complexhydrophilic molecules and highly charged solutes. CE technology can alsobe implemented on microfluidic chips. Depending on the types ofcapillary and buffers used, CE can be further segmented into separationtechniques such as capillary zone electrophoresis (CZE), capillaryisoelectric focusing (CIEF), capillary isotachophoresis (cITP) andcapillary electrochromatography (CEC). An embodiment to couple CEtechniques to electrospray ionization involves the use of volatilesolutions, for example, aqueous mixtures containing a volatile acidand/or base and an organic such as an alcohol or acetonitrile.

Capillary isotachophoresis (cITP) is a technique in which the analytesmove through the capillary at a constant speed but are neverthelessseparated by their respective mobilities. Capillary zone electrophoresis(CZE), also known as free-solution CE (FSCE), is based on differences inthe electrophoretic mobility of the species, determined by the charge onthe molecule, and the frictional resistance the molecule encountersduring migration which is often directly proportional to the size of themolecule. Capillary isoelectric focusing (CIEF) allows weakly-ionizableamphoteric molecules, to be separated by electrophoresis in a pHgradient. CEC is a hybrid technique between traditional high performanceliquid chromatography (HPLC) and CE.

Separation and purification techniques used in the present inventioninclude any chromatography procedures known in the art. Chromatographycan be based on the differential adsorption and elution of certainanalytes or partitioning of analytes between mobile and stationaryphases. Different examples of chromatography include, but not limitedto, liquid chromatography (LC), gas chromatography (GC), highperformance liquid chromatography (HPLC), etc.

In some embodiments, whole blood is collected from the subject andplasma layer is separated by centrifugation. Cell free DNA may be thenextracted from the plasma using methods known in the art. The isolatedcell free DNA can be used to determine the genomic and/or epigenimicalterations of the biomarkers provide herein.

IV. Analyzing Genomic and/or Epigenomic Alterations of Biomarker

Genomic and/or epigenomic alterations of biomarker can be analyzedaccording to the methods described herein and techniques known to theskilled artisan.

a. Methods for Detection of Copy Number

Methods of evaluating the copy number of a biomarker nucleic acid arewell-known to those of skill in the art. The presence or absence ofchromosomal gain or loss can be evaluated simply by a determination ofcopy number of the regions or markers identified herein.

In one embodiment, a biological sample is tested for the presence ofcopy number changes in genomic loci containing the biomarkers in Table1A or 1B.

Methods of evaluating the copy number of a biomarker locus include, butare not limited to, hybridization-based assays. Hybridization-basedassays include, but are not limited to, traditional “direct probe”methods, such as Southern blots, in situ hybridization (e.g., FISH andFISH plus SKY) methods, and “comparative probe” methods, such ascomparative genomic hybridization (CGH), e.g., cDNA-based oroligonucleotide-based CGH. The methods can be used in a wide variety offormats including, but not limited to, substrate (e.g. membrane orglass) bound methods or array-based approaches.

In one embodiment, evaluating the biomarker gene copy number in a sampleinvolves a Southern Blot. In a Southern Blot, the genomic DNA (typicallyfragmented and separated on an electrophoretic gel) is hybridized to aprobe specific for the target region. Comparison of the intensity of thehybridization signal from the probe for the target region with controlprobe signal from analysis of normal genomic DNA (e.g., a non-amplifiedportion of the same or related cell, tissue, organ, etc.) provides anestimate of the relative copy number of the target nucleic acid.Alternatively, a Northern blot may be utilized for evaluating the copynumber of encoding nucleic acid in a sample. In a Northern blot, mRNA ishybridized to a probe specific for the target region. Comparison of theintensity of the hybridization signal from the probe for the targetregion with control probe signal from analysis of normal RNA (e.g., anon-amplified portion of the same or related cell, tissue, organ, etc.)provides an estimate of the relative copy number of the target nucleicacid. Alternatively, other methods well-known in the art to detect RNAcan be used, such that higher or lower expression relative to anappropriate control (e.g., a non-amplified portion of the same orrelated cell tissue, organ, etc.) provides an estimate of the relativecopy number of the target nucleic acid.

An alternative means for determining genomic copy number is in situhybridization (e.g., Angerer (1987) Meth. Enzymol 152: 649). Generally,in situ hybridization comprises the following steps: (1) fixation oftissue or biological structure to be analyzed; (2) prehybridizationtreatment of the biological structure to increase accessibility oftarget DNA, and to reduce nonspecific binding; (3) hybridization of themixture of nucleic acids to the nucleic acid in the biological structureor tissue; (4) post-hybridization washes to remove nucleic acidfragments not bound in the hybridization and (5) detection of thehybridized nucleic acid fragments. The reagent used in each of thesesteps and the conditions for use vary depending on the particularapplication. In a typical in situ hybridization assay, cells are fixedto a solid support, typically a glass slide. If a nucleic acid is to beprobed, the cells are typically denatured with heat or alkali. The cellsare then contacted with a hybridization solution at a moderatetemperature to permit annealing of labeled probes specific to thenucleic acid sequence encoding the protein. The targets (e.g., cells)are then typically washed at a predetermined stringency or at anincreasing stringency until an appropriate signal to noise ratio isobtained. The probes are typically labeled, e.g., with radioisotopes orfluorescent reporters. In one embodiment, probes are sufficiently longso as to specifically hybridize with the target nucleic acid(s) understringent conditions. Probes generally range in length from about 200bases to about 1000 bases. In some applications it is necessary to blockthe hybridization capacity of repetitive sequences. Thus, in someembodiments, tRNA, human genomic DNA, or Cot-I DNA is used to blocknon-specific hybridization.

An alternative means for determining genomic copy number is comparativegenomic hybridization. In general, genomic DNA is isolated from normalreference cells, as well as from test cells (e.g., tumor cells) andamplified, if necessary. The two nucleic acids are differentiallylabeled and then hybridized in situ to metaphase chromosomes of areference cell. The repetitive sequences in both the reference and testDNAs are either removed or their hybridization capacity is reduced bysome means, for example by prehybridization with appropriate blockingnucleic acids and/or including such blocking nucleic acid sequences forsaid repetitive sequences during said hybridization. The bound, labeledDNA sequences are then rendered in a visualizable form, if necessary.Chromosomal regions in the test cells which are at increased ordecreased copy number can be identified by detecting regions where theratio of signal from the two DNAs is altered. For example, those regionsthat have decreased in copy number in the test cells will showrelatively lower signal from the test DNA than the reference compared toother regions of the genome. Regions that have been increased in copynumber in the test cells will show relatively higher signal from thetest DNA. Where there are chromosomal deletions or multiplications,differences in the ratio of the signals from the two labels will bedetected and the ratio will provide a measure of the copy number. Inanother embodiment of CGH, array CGH (aCGH), the immobilized chromosomeelement is replaced with a collection of solid support bound targetnucleic acids on an array, allowing for a large or complete percentageof the genome to be represented in the collection of solid support boundtargets. Target nucleic acids may comprise cDNAs, genomic DNAs,oligonucleotides (e.g., to detect single nucleotide polymorphisms) andthe like. Array-based CGH may also be performed with single-colorlabeling (as opposed to labeling the control and the possible tumorsample with two different dyes and mixing them prior to hybridization,which will yield a ratio due to competitive hybridization of probes onthe arrays). In single color CGH, the control is labeled and hybridizedto one array and absolute signals are read, and the possible tumorsample is labeled and hybridized to a second array (with identicalcontent) and absolute signals are read. Copy number difference iscalculated based on absolute signals from the two arrays. Methods ofpreparing immobilized chromosomes or arrays and performing comparativegenomic hybridization are well-known in the art (see, e.g., U.S. Pat.Nos. 6,335,167; 6,197,501; 5,830,645; and 5,665,549 and Albertson (1984)EMBO J. 3: 1227-1234; Pinkel (1988) Proc. Natl. Acad. Sci. USA 85:9138-9142; EPO Pub. No. 430,402; Methods in Molecular Biology, Vol. 33:In situ Hybridization Protocols, Choo, ed., Humana Press, Totowa, N.J.(1994), etc.) In another embodiment, the hybridization protocol ofPinkel, et al. (1998) Nature Genetics 20: 207-211, or of Kallioniemi(1992) Proc. Natl Acad Sci USA 89:5321-5325 (1992) is used.

In still another embodiment, amplification-based assays can be used tomeasure copy number. In such amplification-based assays, the nucleicacid sequences act as a template in an amplification reaction (e.g.,Polymerase Chain Reaction (PCR). In a quantitative amplification, theamount of amplification product will be proportional to the amount oftemplate in the original sample. Comparison to appropriate controls,e.g. healthy tissue, provides a measure of the copy number.

Methods of “quantitative” amplification are well-known to those of skillin the art. For example, quantitative PCR involves simultaneouslyco-amplifying a known quantity of a control sequence using the sameprimers. This provides an internal standard that may be used tocalibrate the PCR reaction. Detailed protocols for quantitative PCR areprovided in Innis, et al. (1990) PCR Protocols, A Guide to Methods andApplications, Academic Press, Inc. N.Y.). Measurement of DNA copy numberat microsatellite loci using quantitative PCR analysis is described inGinzonger, et al. (2000) Cancer Research 60:5405-5409. The known nucleicacid sequence for the genes is sufficient to enable one of skill in theart to routinely select primers to amplify any portion of the gene.Fluorogenic quantitative PCR may also be used in the methods of thepresent invention. In fluorogenic quantitative PCR, quantitation isbased on amount of fluorescence signals, e.g., TaqMan and SYBR green.

Other suitable amplification methods include, but are not limited to,ligase chain reaction (LCR) (see Wu and Wallace (1989) Genomics 4: 560,Landegren, et al. (1988) Science 241:1077, and Barringer et al. (1990)Gene 89: 117), transcription amplification (Kwoh, et al. (1989) Proc.Natl. Acad. Sci. USA 86: 1173), self-sustained sequence replication(Guatelli, et al. (1990) Proc. Nat. Acad. Sci. USA 87: 1874), dot PCR,and linker adapter PCR, etc.

Loss of heterozygosity (LOH) and major copy proportion (MCP) mapping(Wang, Z. C., et al. (2004) Cancer Res 64(1):64-71; Seymour, A. B., etal. (1994) Cancer Res 54, 2761-4; Hahn, S. A., et al. (1995) Cancer Res55, 4670-5; Kimura, M., et al. (1996) Genes Chromosomes Cancer 17,88-93; Li et al., (2008) MBC Bioinform. 9, 204-219) may also be used toidentify regions of amplification or deletion.

b. Methods for Detection of Biomarker Nucleic Acid Expression

Biomarker expression may be assessed by any of a wide variety ofwell-known methods for detecting expression of a transcribed molecule orprotein. Non-limiting examples of such methods include immunologicalmethods for detection of secreted, cell-surface, cytoplasmic, or nuclearproteins, protein purification methods, protein function or activityassays, nucleic acid hybridization methods, nucleic acid reversetranscription methods, and nucleic acid amplification methods.

In preferred embodiments, activity of a particular gene is characterizedby a measure of gene transcript (e.g. mRNA), by a measure of thequantity of translated protein, or by a measure of gene productactivity. Marker expression can be monitored in a variety of ways,including by detecting mRNA levels, protein levels, or protein activity,any of which can be measured using standard techniques. Detection caninvolve quantification of the level of gene expression (e.g., genomicDNA, cDNA, mRNA, protein, or enzyme activity), or, alternatively, can bea qualitative assessment of the level of gene expression, in particularin comparison with a control level. The type of level being detectedwill be clear from the context.

In another embodiment, detecting or determining expression levels of abiomarker and functionally similar homologs thereof, including afragment or genetic alteration thereof (e.g., in regulatory or promoterregions thereof) comprises detecting or determining RNA levels for themarker of interest. In one embodiment, one or more cells from thesubject to be tested are obtained and RNA is isolated from the cells. Ina preferred embodiment, a sample of breast tissue cells is obtained fromthe subject.

In one embodiment, RNA is obtained from a single cell. For example, acell can be isolated from a tissue sample by laser capturemicrodissection (LCM). Using this technique, a cell can be isolated froma tissue section, including a stained tissue section, thereby assuringthat the desired cell is isolated (see, e.g., Bonner et al. (1997)Science 278: 1481; Emmert-Buck et al. (1996) Science 274:998; Fend etal. (1999) Am. J. Path. 154: 61 and Murakami et al. (2000) Kidney Int.58:1346). For example, Murakami et al., supra, describe isolation of acell from a previously immunostained tissue section.

It is also be possible to obtain cells from a subject and culture thecells in vitro, such as to obtain a larger population of cells fromwhich RNA can be extracted. Methods for establishing cultures ofnon-transformed cells, i.e., primary cell cultures, are known in theart.

When isolating RNA from tissue samples or cells from individuals, it maybe important to prevent any further changes in gene expression after thetissue or cells has been removed from the subject. Changes in expressionlevels are known to change rapidly following perturbations, e.g., heatshock or activation with lipopolysaccharide (LPS) or other reagents. Inaddition, the RNA in the tissue and cells may quickly become degraded.Accordingly, in a preferred embodiment, the tissue or cells obtainedfrom a subject is snap frozen as soon as possible.

RNA can be extracted from the tissue sample by a variety of methods,e.g., the guanidium thiocyanate lysis followed by CsCl centrifugation(Chirgwin et al., 1979, Biochemistry 18:5294-5299). RNA from singlecells can be obtained as described in methods for preparing cDNAlibraries from single cells, such as those described in Dulac, C. (1998)Curr. Top. Dev. Biol. 36, 245 and Jena et al. (1996) J. Immunol. Methods190:199. Care to avoid RNA degradation must be taken, e.g., by inclusionof RNAsin.

The RNA sample can then be enriched in particular species. In oneembodiment, poly(A)+RNA is isolated from the RNA sample. In general,such purification takes advantage of the poly-A tails on mRNA. Inparticular and as noted above, poly-T oligonucleotides may beimmobilized within on a solid support to serve as affinity ligands formRNA. Kits for this purpose are commercially available, e.g., theMessageMaker kit (Life Technologies, Grand Island, N.Y.).

In a preferred embodiment, the RNA population is enriched in markersequences. Enrichment can be undertaken, e.g., by primer-specific cDNAsynthesis, or multiple rounds of linear amplification based on cDNAsynthesis and template-directed in vitro transcription (see, e.g., Wanget al. (1989) Proc. Natl. Acad. Sci. U.S.A. 86: 9717; Dulac et al.,supra, and Jena et al., supra).

The population of RNA, enriched or not in particular species orsequences, can further be amplified. As defined herein, an“amplification process” is designed to strengthen, increase, or augmenta molecule within the RNA. For example, where RNA is mRNA, anamplification process such as RT-PCR can be utilized to amplify themRNA, such that a signal is detectable or detection is enhanced. Such anamplification process is beneficial particularly when the biological,tissue, or tumor sample is of a small size or volume.

Various amplification and detection methods can be used. For example, itis within the scope of the present invention to reverse transcribe mRNAinto cDNA followed by polymerase chain reaction (RT-PCR); or, to use asingle enzyme for both steps as described in U.S. Pat. No. 5,322,770, orreverse transcribe mRNA into cDNA followed by symmetric gap ligase chainreaction (RT-AGLCR) as described by R. L. Marshall, et al., PCR Methodsand Applications 4: 80-84 (1994). Real time PCR may also be used.

Other known amplification methods which can be utilized herein includebut are not limited to the so-called “NASBA” or “3SR” techniquedescribed in PNAS USA 87: 1874-1878 (1990) and also described in Nature350 (No. 6313): 91-92 (1991); Q-beta amplification as described inpublished European Patent Application (EPA) No. 4544610; stranddisplacement amplification (as described in G. T. Walker et al., Clin.Chem. 42: 9-13 (1996) and European Patent Application No. 684315; targetmediated amplification, as described by PCT Publication WO9322461; PCR;ligase chain reaction (LCR) (see, e.g., Wu and Wallace, Genomics 4, 560(1989), Landegren et al., Science 241, 1077 (1988)); self-sustainedsequence replication (SSR) (see, e.g., Guatelli et al., Proc. Nat. Acad.Sci. USA, 87, 1874 (1990)); and transcription amplification (see, e.g.,Kwoh et al., Proc. Natl. Acad. Sci. USA 86, 1173 (1989)).

Many techniques are known in the state of the art for determiningabsolute and relative levels of gene expression, commonly usedtechniques suitable for use in the present invention include Northernanalysis, RNase protection assays (RPA), microarrays and PCR-basedtechniques, such as quantitative PCR and differential display PCR. Forexample, Northern blotting involves running a preparation of RNA on adenaturing agarose gel, and transferring it to a suitable support, suchas activated cellulose, nitrocellulose or glass or nylon membranes.Radiolabeled cDNA or RNA is then hybridized to the preparation, washedand analyzed by autoradiography.

In situ hybridization visualization may also be employed, wherein aradioactively labeled antisense RNA probe is hybridized with a thinsection of a biopsy sample, washed, cleaved with RNase and exposed to asensitive emulsion for autoradiography. The samples may be stained withhematoxylin to demonstrate the histological composition of the sample,and dark field imaging with a suitable light filter shows the developedemulsion. Non-radioactive labels such as digoxigenin may also be used.

Alternatively, mRNA expression can be detected on a DNA array, chip or amicroarray. Labeled nucleic acids of a test sample obtained from asubject may be hybridized to a solid surface comprising biomarker DNA.Positive hybridization signal is obtained with the sample containingbiomarker transcripts. Methods of preparing DNA arrays and their use arewell-known in the art (see, e.g., U.S. Pat. Nos: 6,618,6796; 6,379,897;6,664,377; 6,451,536; 548,257; U.S. 20030157485 and Schena et al. (1995)Science 20, 467-470; Gerhold et al. (1999) Trends In Biochem. Sci. 24,168-173; and Lennon et al. (2000) Drug Discovery Today 5, 59-65, whichare herein incorporated by reference in their entirety). Serial Analysisof Gene Expression (SAGE) can also be performed (See for example U.S.Patent Application 20030215858).

To monitor mRNA levels, for example, mRNA is extracted from thebiological sample to be tested, reverse transcribed, andfluorescently-labeled cDNA probes are generated. The microarrays capableof hybridizing to marker cDNA are then probed with the labeled cDNAprobes, the slides scanned and fluorescence intensity measured. Thisintensity correlates with the hybridization intensity and expressionlevels.

Types of probes that can be used in the methods described herein includecDNA, riboprobes, synthetic oligonucleotides and genomic probes. Thetype of probe used will generally be dictated by the particularsituation, such as riboprobes for in situ hybridization, and cDNA forNorthern blotting, for example. In one embodiment, the probe is directedto nucleotide regions unique to the RNA. The probes may be as short asis required to differentially recognize marker mRNA transcripts, and maybe as short as, for example, 15 bases; however, probes of at least 17,18, 19 or 20 or more bases can be used. In one embodiment, the primersand probes hybridize specifically under stringent conditions to a DNAfragment having the nucleotide sequence corresponding to the marker. Asherein used, the term “stringent conditions” means hybridization willoccur only if there is at least 95% identity in nucleotide sequences. Inanother embodiment, hybridization under “stringent conditions” occurswhen there is at least 97% identity between the sequences.

The form of labeling of the probes may be any that is appropriate, suchas the use of radioisotopes, for example, ³²P and ³⁵S. Labeling withradioisotopes may be achieved, whether the probe is synthesizedchemically or biologically, by the use of suitably labeled bases.

In one embodiment, the biological sample contains polypeptide moleculesfrom the test subject. Alternatively, the biological sample can containmRNA molecules from the test subject or genomic DNA molecules from thetest subject.

In another embodiment, the methods further involve obtaining a controlbiological sample from a control subject, contacting the control samplewith a compound or agent capable of detecting marker polypeptide, mRNA,genomic DNA, or fragments thereof, such that the presence of the markerpolypeptide, mRNA, genomic DNA, or fragments thereof, is detected in thebiological sample, and comparing the presence of the marker polypeptide,mRNA, genomic DNA, or fragments thereof, in the control sample with thepresence of the marker polypeptide, mRNA, genomic DNA, or fragmentsthereof in the test sample.

c. Methods for Detection of Biomarker Protein Expression The activity orlevel of a biomarker protein can be detected and/or quantified bydetecting or quantifying the expressed polypeptide. The polypeptide canbe detected and quantified by any of a number of means well-known tothose of skill in the art. Such methods include, but are not limited to,immunodiffusion, immunoelectrophoresis, radioimmunoassay (RIA),enzyme-linked immunosorbent assays (ELISAs), immunofluorescent assays,Western blotting, binder-ligand assays, immunohistochemical techniques,agglutination, complement assays, high performance liquid chromatography(HPLC), thin layer chromatography (TLC), hyperdiffusion chromatography,and the like (e.g., Basic and Clinical Immunology, Sites and Terr, eds.,Appleton and Lange, Norwalk, Conn. pp 217-262, 1991 which isincorporated by reference). Preferred are binder-ligand immunoassaymethods including reacting antibodies with an epitope or epitopes andcompetitively displacing a labeled polypeptide or derivative thereof.

For example, ELISA and RIA procedures may be conducted such that adesired biomarker protein standard is labeled (with a radioisotope suchas ¹²⁵I or ³⁵S, or an assayable enzyme, such as horseradish peroxidaseor alkaline phosphatase), and, together with the unlabeled sample,brought into contact with the corresponding antibody, whereon a secondantibody is used to bind the first, and radioactivity or the immobilizedenzyme assayed (competitive assay). Alternatively, the biomarker proteinin the sample is allowed to react with the corresponding immobilizedantibody, radioisotope- or enzyme-labeled anti-biomarker proteinantibody is allowed to react with the system, and radioactivity or theenzyme assayed (ELISA-sandwich assay). Other conventional methods mayalso be employed as suitable.

The above techniques may be conducted essentially as a “one-step” or“two-step” assay. A “one-step” assay involves contacting antigen withimmobilized antibody and, without washing, contacting the mixture withlabeled antibody. A “two-step” assay involves washing before contacting,the mixture with labeled antibody. Other conventional methods may alsobe employed as suitable.

In one embodiment, a method for measuring biomarker protein levelscomprises the steps of: contacting a biological specimen with anantibody or variant (e.g., fragment) thereof which selectively binds thebiomarker protein, and detecting whether said antibody or variantthereof is bound to said sample and thereby measuring the levels of thebiomarker protein.

Enzymatic and radiolabeling of biomarker protein and/or the antibodiesmay be effected by conventional means. Such means will generally includecovalent linking of the enzyme to the antigen or the antibody inquestion, such as by glutaraldehyde, specifically so as not to adverselyaffect the activity of the enzyme, by which is meant that the enzymemust still be capable of interacting with its substrate, although it isnot necessary for all of the enzyme to be active, provided that enoughremains active to permit the assay to be effected. Indeed, sometechniques for binding enzyme are non-specific (such as usingformaldehyde), and will only yield a proportion of active enzyme.

It is usually desirable to immobilize one component of the assay systemon a support, thereby allowing other components of the system to bebrought into contact with the component and readily removed withoutlaborious and time-consuming labor. It is possible for a second phase tobe immobilized away from the first, but one phase is usually sufficient.

It is possible to immobilize the enzyme itself on a support, but ifsolid-phase enzyme is required, then this is generally best achieved bybinding to antibody and affixing the antibody to a support, models andsystems for which are well-known in the art. Simple polyethylene mayprovide a suitable support.

Enzymes employable for labeling are not particularly limited, but may beselected from the members of the oxidase group, for example. Thesecatalyze production of hydrogen peroxide by reaction with theirsubstrates, and glucose oxidase is often used for its good stability,ease of availability and cheapness, as well as the ready availability ofits substrate (glucose). Activity of the oxidase may be assayed bymeasuring the concentration of hydrogen peroxide formed after reactionof the enzyme-labeled antibody with the substrate under controlledconditions well-known in the art.

Other techniques may be used to detect biomarker protein according to apractitioner's preference based upon the present disclosure. One suchtechnique is Western blotting (Towbin et at., Proc. Nat. Acad. Sci.76:4350 (1979)), wherein a suitably treated sample is run on an SDS-PAGEgel before being transferred to a solid support, such as anitrocellulose filter. Anti-biomarker protein antibodies (unlabeled) arethen brought into contact with the support and assayed by a secondaryimmunological reagent, such as labeled protein A or anti-immunoglobulin(suitable labels including ¹²⁵I, horseradish peroxidase and alkalinephosphatase). Chromatographic detection may also be used.

Immunohistochemistry may be used to detect expression of biomarkerprotein, e.g., in a biopsy sample. A suitable antibody is brought intocontact with, for example, a thin layer of cells, washed, and thencontacted with a second, labeled antibody. Labeling may be byfluorescent markers, enzymes, such as peroxidase, avidin, orradiolabeling. The assay is scored visually, using microscopy.

Anti-biomarker protein antibodies, such as intrabodies, may also be usedfor imaging purposes, for example, to detect the presence of biomarkerprotein in cells and tissues of a subject. Suitable labels includeradioisotopes, iodine (¹²⁵I, ¹²¹I) carbon (¹⁴C), sulphur (³⁵S), tritium(³H), indium (¹¹²In), and technetium (⁹⁹mTc), fluorescent labels, suchas fluorescein and rhodamine, and biotin.

For in vivo imaging purposes, antibodies are not detectable, as such,from outside the body, and so must be labeled, or otherwise modified, topermit detection. Markers for this purpose may be any that do notsubstantially interfere with the antibody binding, but which allowexternal detection. Suitable markers may include those that may bedetected by X-radiography, NMR or MM. For X-radiographic techniques,suitable markers include any radioisotope that emits detectableradiation but that is not overtly harmful to the subject, such as bariumor cesium, for example. Suitable markers for NMR and MM generallyinclude those with a detectable characteristic spin, such as deuterium,which may be incorporated into the antibody by suitable labeling ofnutrients for the relevant hybridoma, for example.

The size of the subject, and the imaging system used, will determine thequantity of imaging moiety needed to produce diagnostic images. In thecase of a radioisotope moiety, for a human subject, the quantity ofradioactivity injected will normally range from about 5 to 20millicuries of technetium-99. The labeled antibody or antibody fragmentwill then preferentially accumulate at the location of cells whichcontain biomarker protein. The labeled antibody or antibody fragment canthen be detected using known techniques.

Antibodies that may be used to detect biomarker protein include anyantibody, whether natural or synthetic, full length or a fragmentthereof, monoclonal or polyclonal, that binds sufficiently strongly andspecifically to the biomarker protein to be detected. An antibody mayhave a K_(d) of at most about 10⁻⁶M, 10⁻⁷M, 10⁻⁸M, 10⁻⁹M, 10⁻¹⁰ M, 10⁻¹¹M, 10⁻¹²M. The phrase “specifically binds” refers to binding of, forexample, an antibody to an epitope or antigen or antigenic determinantin such a manner that binding can be displaced or competed with a secondpreparation of identical or similar epitope, antigen or antigenicdeterminant. An antibody may bind preferentially to the biomarkerprotein relative to other proteins, such as related proteins.

Antibodies are commercially available or may be prepared according tomethods known in the art.

Antibodies and derivatives thereof that may be used encompass polyclonalor monoclonal antibodies, chimeric, human, humanized, primatized(CDR-grafted), veneered or single-chain antibodies as well as functionalfragments, i.e., biomarker protein binding fragments, of antibodies. Forexample, antibody fragments capable of binding to a biomarker protein orportions thereof, including, but not limited to, Fv, Fab, Fab′ andF(ab′) 2 fragments can be used. Such fragments can be produced byenzymatic cleavage or by recombinant techniques. For example, papain orpepsin cleavage can generate Fab or F(ab′) 2 fragments, respectively.Other proteases with the requisite substrate specificity can also beused to generate Fab or F(ab′) 2 fragments. Antibodies can also beproduced in a variety of truncated forms using antibody genes in whichone or more stop codons have been introduced upstream of the naturalstop site. For example, a chimeric gene encoding a F(ab′) 2 heavy chainportion can be designed to include DNA sequences encoding the CH, domainand hinge region of the heavy chain.

Synthetic and engineered antibodies are described in, e.g., Cabilly etal., U.S. Pat. No. 4,816,567 Cabilly et al., European Patent No.0,125,023 B1; Boss et al., U.S. Pat. No. 4,816,397; Boss et al.,European Patent No. 0,120,694 B1; Neuberger, M. S. et al., WO 86/01533;Neuberger, M. S. et al., European Patent No. 0,194,276 B1; Winter, U.S.Pat. No. 5,225,539; Winter, European Patent No. 0,239,400 B1; Queen etal., European Patent No. 0451216 B1; and Padlan, E. A. et al., EP0519596 A1. See also, Newman, R. et al., BioTechnology, 10: 1455-1460(1992), regarding primatized antibody, and Ladner et al., U.S. Pat. No.4,946,778 and Bird, R. E. et al., Science, 242: 423-426 (1988))regarding single-chain antibodies. Antibodies produced from a library,e.g., phage display library, may also be used.

In some embodiments, agents that specifically bind to a biomarkerprotein other than antibodies are used, such as peptides. Peptides thatspecifically bind to a biomarker protein can be identified by any meansknown in the art. For example, specific peptide binders of a biomarkerprotein can be screened for using peptide phage display libraries.

d. Methods for Detection of Biomarker Structural Alterations

The following illustrative methods can be used to identify the presenceof a structural alteration (e.g., genomic muations) in a biomarker(e.g., biomarkers in Tables 1A and 1B) in order to, for example, assesswhether a subject is affliacted with CRPC-NE or at the risk ofdeveloping CRPC-NE.

In certain embodiments, detection of the alteration involves the use ofa probe/primer in a polymerase chain reaction (PCR) (see, e.g., U.S.Pat. Nos. 4,683,195 and 4,683,202), such as anchor PCR or RACE PCR, or,alternatively, in a ligation chain reaction (LCR) (see, e.g., Landegranet al. (1988) Science 241:1077-1080; and Nakazawa et al. (1994) Proc.Natl. Acad. Sci. USA 91:360-364), the latter of which can beparticularly useful for detecting point mutations in a biomarker nucleicacid such as a biomarker gene (see Abravaya et al. (1995) Nucleic AcidsRes. 23:675-682). This method can include the steps of collecting asample of cells from a subject, isolating nucleic acid (e.g., genomic,mRNA or both) from the cells of the sample, contacting the nucleic acidsample with one or more primers which specifically hybridize to abiomarker gene under conditions such that hybridization andamplification of the biomarker gene (if present) occurs, and detectingthe presence or absence of an amplification product, or detecting thesize of the amplification product and comparing the length to a controlsample. It is anticipated that PCR and/or LCR may be desirable to use asa preliminary amplification step in conjunction with any of thetechniques used for detecting mutations described herein.

Alternative amplification methods include: self-sustained sequencereplication (Guatelli, J. C. et al. (1990) Proc. Natl. Acad. Sci. USA87:1874-1878), transcriptional amplification system (Kwoh, D. Y. et al.(1989) Proc. Natl. Acad. Sci. USA 86:1173-1177), Q-Beta Replicase(Lizardi, P. M. et al. (1988) Bio-Technology 6:1197), or any othernucleic acid amplification method, followed by the detection of theamplified molecules using techniques well-known to those of skill in theart. These detection schemes are especially useful for the detection ofnucleic acid molecules if such molecules are present in very lownumbers.

In an alternative embodiment, mutations in a biomarker nucleic acid froma sample cell can be identified by alterations in restriction enzymecleavage patterns. For example, sample and control DNA is isolated,amplified (optionally), digested with one or more restrictionendonucleases, and fragment length sizes are determined by gelelectrophoresis and compared. Differences in fragment length sizesbetween sample and control DNA indicates mutations in the sample DNA.Moreover, the use of sequence specific ribozymes (see, for example, U.S.Pat. No. 5,498,531) can be used to score for the presence of specificmutations by development or loss of a ribozyme cleavage site.

In other embodiments, genetic mutations in biomarker nucleic acid can beidentified by hybridizing a sample and control nucleic acids, e.g., DNAor RNA, to high density arrays containing hundreds or thousands ofoligonucleotide probes (Cronin, M. T. et al. (1996) Hum. Mutat.7:244-255; Kozal, M. J. et al. (1996) Nat. Med. 2:753-759). For example,biomarker genetic mutations can be identified in two dimensional arrayscontaining light-generated DNA probes as described in Cronin et al.(1996) supra. Briefly, a first hybridization array of probes can be usedto scan through long stretches of DNA in a sample and control toidentify base changes between the sequences by making linear arrays ofsequential, overlapping probes. This step allows the identification ofpoint mutations. This step is followed by a second hybridization arraythat allows the characterization of specific mutations by using smaller,specialized probe arrays complementary to all variants or mutationsdetected. Each mutation array is composed of parallel probe sets, onecomplementary to the wild-type gene and the other complementary to themutant gene. Such biomarker genetic mutations can be identified in avariety of contexts, including, for example, germline and somaticmutations.

In yet another embodiment, any of a variety of sequencing reactionsknown in the art can be used to directly sequence a biomarker gene anddetect mutations by comparing the sequence of the sample biomarker withthe corresponding wild-type (control) sequence. Examples of sequencingreactions include those based on techniques developed by Maxam andGilbert (1977) Proc. Natl. Acad. Sci. USA 74:560 or Sanger (1977) Proc.Natl. Acad Sci. USA 74:5463. It is also contemplated that any of avariety of automated sequencing procedures can be utilized whenperforming the diagnostic assays (Naeve (1995) Biotechniques 19:448-53),including sequencing by mass spectrometry (see, e.g., PCT InternationalPublication No. WO 94/16101; Cohen et al. (1996) Adv. Chromatogr.36:127-162; and Griffin et al. (1993) Appl. Biochem. Biotechnol.38:147-159).

Other methods for detecting mutations in a biomarker gene includemethods in which protection from cleavage agents is used to detectmismatched bases in RNA/RNA or RNA/DNA heteroduplexes (Myers et al.(1985) Science 230:1242). In general, the art technique of “mismatchcleavage” starts by providing heteroduplexes formed by hybridizing(labeled) RNA or DNA containing the wild-type biomarker sequence withpotentially mutant RNA or DNA obtained from a tissue sample. Thedouble-stranded duplexes are treated with an agent which cleavessingle-stranded regions of the duplex such as which will exist due tobase pair mismatches between the control and sample strands. Forinstance, RNA/DNA duplexes can be treated with RNase and DNA/DNA hybridstreated with SI nuclease to enzymatically digest the mismatched regions.In other embodiments, either DNA/DNA or RNA/DNA duplexes can be treatedwith hydroxylamine or osmium tetroxide and with piperidine in order todigest mismatched regions. After digestion of the mismatched regions,the resulting material is then separated by size on denaturingpolyacrylamide gels to determine the site of mutation. See, for example,Cotton et al. (1988) Proc. Natl. Acad. Sci. USA 85:4397 and Saleeba etal. (1992) Methods Enzymol. 217:286-295. In a preferred embodiment, thecontrol DNA or RNA can be labeled for detection.

In still another embodiment, the mismatch cleavage reaction employs oneor more proteins that recognize mismatched base pairs in double-strandedDNA (so called “DNA mismatch repair” enzymes) in defined systems fordetecting and mapping point mutations in biomarker cDNAs obtained fromsamples of cells. For example, the mutY enzyme of E. coli cleaves A atG/A mismatches and the thymidine DNA glycosylase from HeLa cells cleavesT at G/T mismatches (Hsu et al. (1994) Carcinogenesis 15:1657-1662).According to an exemplary embodiment, a probe based on a biomarkersequence, e.g., a wild-type biomarker treated with a DNA mismatch repairenzyme, and the cleavage products, if any, can be detected fromelectrophoresis protocols or the like (e.g., U.S. Pat. No. 5,459,039.)

In other embodiments, alterations in electrophoretic mobility can beused to identify mutations in biomarker genes. For example, singlestrand conformation polymorphism (SSCP) may be used to detectdifferences in electrophoretic mobility between mutant and wild typenucleic acids (Orita et al. (1989) Proc Natl. Acad. Sci USA 86:2766; seealso Cotton (1993) Mutat. Res. 285:125-144 and Hayashi (1992) Genet.Anal. Tech. Appl. 9:73-79). Single-stranded DNA fragments of sample andcontrol biomarker nucleic acids will be denatured and allowed torenature. The secondary structure of single-stranded nucleic acidsvaries according to sequence, the resulting alteration inelectrophoretic mobility enables the detection of even a single basechange. The DNA fragments may be labeled or detected with labeledprobes. The sensitivity of the assay may be enhanced by using RNA(rather than DNA), in which the secondary structure is more sensitive toa change in sequence. In a preferred embodiment, the subject methodutilizes heteroduplex analysis to separate double stranded heteroduplexmolecules on the basis of changes in electrophoretic mobility (Keen etal. (1991) Trends Genet. 7:5).

In yet another embodiment the movement of mutant or wild-type fragmentsin polyacrylamide gels containing a gradient of denaturant is assayedusing denaturing gradient gel electrophoresis (DGGE) (Myers et al.(1985) Nature 313:495). When DGGE is used as the method of analysis, DNAwill be modified to ensure that it does not completely denature, forexample by adding a GC clamp of approximately 40 bp of high-meltingGC-rich DNA by PCR. In a further embodiment, a temperature gradient isused in place of a denaturing gradient to identify differences in themobility of control and sample DNA (Rosenbaum and Reissner (1987)Biophys. Chem. 265:12753).

Examples of other techniques for detecting point mutations include, butare not limited to, selective oligonucleotide hybridization, selectiveamplification, or selective primer extension. For example,oligonucleotide primers may be prepared in which the known mutation isplaced centrally and then hybridized to target DNA under conditionswhich permit hybridization only if a perfect match is found (Saiki etal. (1986) Nature 324:163; Saiki et al. (1989) Proc. Natl. Acad. Sci.USA 86:6230). Such allele specific oligonucleotides are hybridized toPCR amplified target DNA or a number of different mutations when theoligonucleotides are attached to the hybridizing membrane and hybridizedwith labeled target DNA.

Alternatively, allele specific amplification technology which depends onselective PCR amplification may be used in conjunction with the instantinvention. Oligonucleotides used as primers for specific amplificationmay carry the mutation of interest in the center of the molecule (sothat amplification depends on differential hybridization) (Gibbs et al.(1989) Nucleic Acids Res. 17:2437-2448) or at the extreme 3′ end of oneprimer where, under appropriate conditions, mismatch can prevent, orreduce polymerase extension (Prossner (1993) Tibtech 11:238). Inaddition it may be desirable to introduce a novel restriction site inthe region of the mutation to create cleavage-based detection (Gaspariniet al. (1992) Mol. Cell Probes 6:1). It is anticipated that in certainembodiments amplification may also be performed using Taq ligase foramplification (Barany (1991) Proc. Natl. Acad. Sci USA 88:189). In suchcases, ligation will occur only if there is a perfect match at the 3′end of the 5′ sequence making it possible to detect the presence of aknown mutation at a specific site by looking for the presence or absenceof amplification.

e. Methods for Detection of Biomarker Epigenomic Alterations

The presence of hypermethylation or hypomethylation at genmic siteslisted in Tables 1C and 1D can be detected and quantified by any of anumber of means well-known to those of skill in the art. Such methodsinclude, but are not limited to, differential enzymatic cleavage of DNA,digestion followed by PCR or sequencing, bisulfite conversion followedby methylation-specific PCR or sequencing, whole genome bisulfitesequencing (WGBS), PCR with high resolution melting, COLD-PCR for thedetection of unmethylated islands, reduced representation bisulfitesequencing (RRBS), methyl-sensitive cut counting (MSCC), highperformance liquid chromatography-ultraviolet (HPLC-UV), liquidchromatography coupled with tandem mass spectrometry (LC-MS/MS), ELISA,amplification fragment length polymorphism (AFLP), restriction fragmentlength polymorphism (RFLP), bead array (e.g., HumanMethylation450BeadChip array), luminometric methylation assay (LUMA),LINE-1/pyrosequencing, and affinity capture of methylated DNA (Laird(2010) Nat. Rev. Genet. 11:191-203; Kurdyukov et al. (2016) Biology5:3). Restriction enzyme based differential cleavage of methylated DNAmay be locus-specific. Affinity-capture and bisulphite conversionfollowed by sequencing methods may be used for both gene specific orgenome-wide analysis (Beck (2010) Nat. Biotech. 28:1026-1028). Thecommonly reported DNA affinity capture method may include methylated DNAimmunoprecipitation (Me-DIP) that uses methyl DNA specific antibody, ormethyl capture using methyl-CpG binding domain (MBD) proteins. Incertain embodiment, whole genome bisulfite sequencing (WGBS) is used todetect the methylation level at genmic sites listed in Tables 1C and 1D.

V. Anti-Cancer Therapies

Methods described herein can be used to assess whether a subject isafflicted with castration-resistant neuroendocrine prosate cancer(CRPC-NE) or at risk for developing CRPC-NE. In one embodiment, thesubject is administered with an anti-cancer therapy (e.g.,platinum-based chemotherapy) other than an AR-targeted therapy as asingle agent if the subject is afflicted with CRPC-NE or at risk fordeveloping CRPC-NE. In another embodiment, the subject is administeredwith an AR-targeted therapy if the subject is not afflicted with CRPC-NEor not at risk for developing CRPC-NE. The anti-cancer therapy isselected from the group consisting of an epgenitic modifier, targetedtherapy, chemotherapy, radiation therapy, and/or hormonal therapy,optionally wherein the anti-cancer therapy comprises an AR-targetedtherapy.

Combination therapies are also contemplated and can comprise, forexample, one or more chemotherapeutic agents and radiation, one or morechemotherapeutic agents and immunotherapy, or one or morechemotherapeutic agents, radiation and chemotherapy, each combination ofwhich can be with the AR-targeted therapy.

The term “targeted therapy” refers to administration of agents thatselectively interact with a chosen biomolecule to thereby treat cancer.One example includes immunotherapies such as immune checkpointinhibitors, which are well-known in the art. For example, anti-PD-1pathway agents, such as therapeutic monoclonal blocking antibodies,which are well-known in the art and described above, can be used totarget tumor microenvironments and cells expressing unwanted componentsof the PD-1 pathway, such as PD-1, PD-L1, and/or PD-L2.

For example, the term “PD-1 pathway” refers to the PD-1 receptor and itsligands, PD-L1 and PD-L2. “PD-1 pathway inhibitors” block or otherwisereduce the interaction between PD-1 and one or both of its ligands suchthat the immunoinhibitory signaling otherwise generated by theinteraction is blocked or otherwise reduced. Anti-immune checkpointinhibitors can be direct or indirect. Direct anti-immune checkpointinhibitors block or otherwise reduce the interaction between an immunecheckpoint and at least one of its ligands. For example, PD-1 inhibitorscan block PD-1 binding with one or both of its ligands. Direct PD-1combination inhibitors are well-known in the art, especially since thenatural binding partners of PD-1 (e.g., PD-L1 and PD-L2), PD-L1 (e.g.,PD-1 and B7-1), and PD-L2 (e.g., PD-1 and RGMb) are known.

For example, agents which directly block the interaction between PD-1and PD-L1, PD-1 and PD-L2, PD-1 and both PD-L1 and PD-L2, such as abispecific antibody, can prevent inhibitory signaling and upregulate animmune response (i.e., as a PD-1 pathway inhibitor). Alternatively,agents that indirectly block the interaction between PD-1 and one orboth of its ligands can prevent inhibitory signaling and upregulate animmune response. For example, B7-1 or a soluble form thereof, by bindingto a PD-L1 polypeptide indirectly reduces the effective concentration ofPD-L1 polypeptide available to bind to PD-1. Exemplary agents includemonospecific or bispecific blocking antibodies against PD-1, PD-L1,and/or PD-L2 that block the interaction between the receptor andligand(s); a non-activating form of PD-1, PD-L1, and/or PD-L2 (e.g., adominant negative or soluble polypeptide), small molecules or peptidesthat block the interaction between PD-1, PD-L1, and/or PD-L2; fusionproteins (e.g. the extracellular portion of PD-1, PD-L1, and/or PD-L2,fused to the Fc portion of an antibody or immunoglobulin) that bind toPD-1, PD-L1, and/or PD-L2 and inhibit the interaction between thereceptor and ligand(s); a non-activating form of a natural PD-1, PD-L2,and/or PD-L2 ligand, and a soluble form of a natural PD-1, PD-L2, and/orPD-L2 ligand.

Indirect anti-immune checkpoint inhibitors block or otherwise reduce theimmunoinhibitory signaling generated by the interaction between theimmune checkpoint and at least one of its ligands. For example, aninhibitor can block the interaction between PD-1 and one or both of itsligands without necessarily directly blocking the interaction betweenPD-1 and one or both of its ligands. For example, indirect inhibitorsinclude intrabodies that bind the intracellular portion of PD-1 and/orPD-L1 required to signal to block or otherwise reduce theimmunoinhibitory signaling. Similarly, nucleic acids that reduce theexpression of PD-1, PD-L1, and/or PD-L2 can indirectly inhibit theinteraction between PD-1 and one or both of its ligands by removing theavailability of components for interaction. Such nucleic acid moleculescan block PD-L1, PD-L2, and/or PD-L2 transcription or translation.

Immunotherapies that are designed to elicit or amplify an immuneresponse are referred to as “activation immunotherapies.”Immunotherapies that are designed to reduce or suppress an immuneresponse are referred to as “suppression immunotherapies.” Any agentbelieved to have an immune system effect on the genetically modifiedtransplanted cancer cells can be assayed to determine whether the agentis an immunotherapy and the effect that a given genetic modification hason the modulation of immune response. In some embodiments, theimmunotherapy is cancer cell-specific. In some embodiments,immunotherapy can be “untargeted,” which refers to administration ofagents that do not selectively interact with immune system cells, yetmodulates immune system function. Representative examples of untargetedtherapies include, without limitation, chemotherapy, gene therapy, andradiation therapy.

Immunotherapy can involve passive immunity for short-term protection ofa host, achieved by the administration of pre-formed antibody directedagainst a cancer antigen or disease antigen (e.g., administration of amonoclonal antibody, optionally linked to a chemotherapeutic agent ortoxin, to a tumor antigen). Immunotherapy can also focus on using thecytotoxic lymphocyte-recognized epitopes of cancer cell lines.Alternatively, antisense polynucleotides, ribozymes, RNA interferencemolecules, triple helix polynucleotides and the like, can be used toselectively modulate biomolecules that are linked to the initiation,progression, and/or pathology of a tumor or cancer.

In one embodiment, immunotherapy comprises adoptive cell-basedimmunotherapies. Well-known adoptive cell-based immunotherapeuticmodalities, including, without limitation, Irradiated autologous orallogeneic tumor cells, tumor lysates or apoptotic tumor cells,antigen-presenting cell-based immunotherapy, dendritic cell-basedimmunotherapy, adoptive T cell transfer, adoptive CAR T cell therapy,autologous immune enhancement therapy (MET), cancer vaccines, and/orantigen presenting cells. Such cell-based immunotherapies can be furthermodified to express one or more gene products to further modulate immuneresponses, such as expressing cytokines like GM-CSF, and/or to expresstumor-associated antigen (TAA) antigens, such as Mage-1, gp-100,patient-specific neoantigen vaccines, and the like.

In another embodiment, immunotherapy comprises non-cell-basedimmunotherapies. In one embodiment, compositions comprising antigenswith or without vaccine-enhancing adjuvants are used. Such compositionsexist in many well-known forms, such as peptide compositions, oncolyticviruses, recombinant antigen comprising fusion proteins, and the like.In still another embodiment, immunomodulatory interleukins, such asIL-2, IL-6, IL-7, IL-12, IL-17, IL-23, and the like, as well asmodulators thereof (e.g., blocking antibodies or more potent or longerlasting forms) are used. In yet another embodiment, immunomodulatorycytokines, such as interferons, G-CSF, imiquimod, TNFalpha, and thelike, as well as modulators thereof (e.g., blocking antibodies or morepotent or longer lasting forms) are used. In another embodiment,immunomodulatory chemokines, such as CCL3, CCL26, and CXCL7, and thelike, as well as modulators thereof (e.g., blocking antibodies or morepotent or longer lasting forms) are used. In another embodiment,immunomodulatory molecules targeting immunosuppression, such as STAT3signaling modulators, NFkappaB signaling modulators, and immunecheckpoint modulators, are used. The terms “immune checkpoint” and“anti-immune checkpoint therapy” are described above.

Similarly, agents and therapies other than immunotherapy or incombination thereof can be used with in combination with biomarkerinhibitor/immunotherapies to stimulate an immune response to therebytreat a condition that would benefit therefrom. For example,chemotherapy, radiation, epigenetic modifiers (e.g., histone deacetylase(HDAC) modifiers, methylation modifiers, phosphorylation modifiers, andthe like), targeted therapy, and the like are well-known in the art.

The term “untargeted therapy” refers to administration of agents that donot selectively interact with a chosen biomolecule yet treat cancer.Representative examples of untargeted therapies include, withoutlimitation, chemotherapy, gene therapy, and radiation therapy.

In one embodiment, chemotherapy is used. Chemotherapy includes theadministration of a chemotherapeutic agent. Such a chemotherapeuticagent may be, but is not limited to, those selected from among thefollowing groups of compounds: platinum compounds, cytotoxicantibiotics, antimetabolites, anti-mitotic agents, alkylating agents,arsenic compounds, DNA topoisomerase inhibitors, taxanes, nucleosideanalogues, plant alkaloids, and toxins; and synthetic derivativesthereof. Exemplary compounds include, but are not limited to, alkylatingagents: cisplatin, treosulfan, and trofosfamide; plant alkaloids:vinblastine, paclitaxel, docetaxol; DNA topoisomerase inhibitors:teniposide, crisnatol, and mitomycin; anti-folates: methotrexate,mycophenolic acid, and hydroxyurea; pyrimidine analogs: 5-fluorouracil,doxifluridine, and cytosine arabinoside; purine analogs: mercaptopurineand thioguanine; DNA antimetabolites: 2′-deoxy-5-fluorouridine,aphidicolin glycinate, and pyrazoloimidazole; and antimitotic agents:halichondrin, colchicine, and rhizoxin. Compositions comprising one ormore chemotherapeutic agents (e.g., FLAG, CHOP) may also be used. FLAGcomprises fludarabine, cytosine arabinoside (Ara-C) and G-CSF. CHOPcomprises cyclophosphamide, vincristine, doxorubicin, and prednisone. Inanother embodiments, PARP (e.g., PARP-1 and/or PARP-2) inhibitors areused and such inhibitors are well-known in the art (e.g., Olaparib,ABT-888, BSI-201, BGP-15 (N-Gene Research Laboratories, Inc.); INO-1001(Inotek Pharmaceuticals Inc.); PJ34 (Soriano et al., 2001; Pacher etal., 2002b); 3-aminobenzamide (Trevigen); 4-amino-1,8-naphthalimide;(Trevigen); 6(5H)-phenanthridinone (Trevigen); benzamide (U.S. Pat. Re.36,397); and NU1025 (Bowman et al.). The mechanism of action isgenerally related to the ability of PARP inhibitors to bind PARP anddecrease its activity. PARP catalyzes the conversion of.beta.-nicotinamide adenine dinucleotide (NAD+) into nicotinamide andpoly-ADP-ribose (PAR). Both poly (ADP-ribose) and PARP have been linkedto regulation of transcription, cell proliferation, genomic stability,and carcinogenesis (Bouchard V. J. et. al. Experimental Hematology,Volume 31, Number 6, June 2003, pp. 446-454(9); Herceg Z.; Wang Z.-Q.Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis,Volume 477, Number 1, 2 Jun. 2001, pp. 97-110(14)). Poly(ADP-ribose)polymerase 1 (PARP1) is a key molecule in the repair of DNAsingle-strand breaks (SSBs) (de Murcia J. et al. 1997. Proc Natl AcadSci USA 94:7303-7307; Schreiber V, Dantzer F, Ame J C, de Murcia G(2006) Nat Rev Mol Cell Biol 7:517-528; Wang Z Q, et al. (1997) GenesDev 11:2347-2358). Knockout of SSB repair by inhibition of PARP1function induces DNA double-strand breaks (DSBs) that can triggersynthetic lethality in cancer cells with defective homology-directed DSBrepair (Bryant H E, et al. (2005) Nature 434:913-917; Farmer H, et al.(2005) Nature 434:917-921). The foregoing examples of chemotherapeuticagents are illustrative, and are not intended to be limiting.

In another embodiment, radiation therapy is used. The radiation used inradiation therapy can be ionizing radiation. Radiation therapy can alsobe gamma rays, X-rays, or proton beams. Examples of radiation therapyinclude, but are not limited to, external-beam radiation therapy,interstitial implantation of radioisotopes (I-125, palladium, iridium),radioisotopes such as strontium-89, thoracic radiation therapy,intraperitoneal P-32 radiation therapy, and/or total abdominal andpelvic radiation therapy. For a general overview of radiation therapy,see Hellman, Chapter 16: Principles of Cancer Management: RadiationTherapy, 6th edition, 2001, DeVita et al., eds., J. B. LippencottCompany, Philadelphia. The radiation therapy can be administered asexternal beam radiation or teletherapy wherein the radiation is directedfrom a remote source. The radiation treatment can also be administeredas internal therapy or brachytherapy wherein a radioactive source isplaced inside the body close to cancer cells or a tumor mass. Alsoencompassed is the use of photodynamic therapy comprising theadministration of photosensitizers, such as hematoporphyrin and itsderivatives, Vertoporfin (BPD-MA), phthalocyanine, photosensitizer Pc4,demethoxy-hypocrellin A; and 2BA-2-DMHA.

In another embodiment, surgical intervention can occur to physicallyremove cancerous cells and/or tissues.

In still another embodiment, hormone therapy is used. Hormonaltherapeutic treatments can comprise, for example, hormonal agonists,hormonal antagonists (e.g., flutamide, bicalutamide, tamoxifen,raloxifene, leuprolide acetate (LUPRON), LH-RH antagonists), inhibitorsof hormone biosynthesis and processing, and steroids (e.g.,dexamethasone, retinoids, deltoids, betamethasone, cortisol, cortisone,prednisone, dehydrotestosterone, glucocorticoids, mineralocorticoids,estrogen, testosterone, progestins), vitamin A derivatives (e.g.,all-trans retinoic acid (ATRA)); vitamin D3 analogs; antigestagens(e.g., mifepristone, onapristone), or antiandrogens (e.g., cyproteroneacetate).

In yet another embodiment, hyperthermia, a procedure in which bodytissue is exposed to high temperatures (up to 106° F.) is used. Heat mayhelp shrink tumors by damaging cells or depriving them of substancesthey need to live. Hyperthermia therapy can be local, regional, andwhole-body hyperthermia, using external and internal heating devices.Hyperthermia is almost always used with other forms of therapy (e.g.,radiation therapy, chemotherapy, and biological therapy) to try toincrease their effectiveness. Local hyperthermia refers to heat that isapplied to a very small area, such as a tumor. The area may be heatedexternally with high-frequency waves aimed at a tumor from a deviceoutside the body. To achieve internal heating, one of several types ofsterile probes may be used, including thin, heated wires or hollow tubesfilled with warm water; implanted microwave antennae; and radiofrequencyelectrodes. In regional hyperthermia, an organ or a limb is heated.Magnets and devices that produce high energy are placed over the regionto be heated. In another approach, called perfusion, some of thepatient's blood is removed, heated, and then pumped (perfused) into theregion that is to be heated internally. Whole-body heating is used totreat metastatic cancer that has spread throughout the body. It can beaccomplished using warm-water blankets, hot wax, inductive coils (likethose in electric blankets), or thermal chambers (similar to largeincubators). Hyperthermia does not cause any marked increase inradiation side effects or complications. Heat applied directly to theskin, however, can cause discomfort or even significant local pain inabout half the patients treated. It can also cause blisters, whichgenerally heal rapidly.

In still another embodiment, photodynamic therapy (also called PDT,photoradiation therapy, phototherapy, or photochemotherapy) is used forthe treatment of some types of cancer. It is based on the discovery thatcertain chemicals known as photosensitizing agents can kill one-celledorganisms when the organisms are exposed to a particular type of light.PDT destroys cancer cells through the use of a fixed-frequency laserlight in combination with a photosensitizing agent. In PDT, thephotosensitizing agent is injected into the bloodstream and absorbed bycells all over the body. The agent remains in cancer cells for a longertime than it does in normal cells. When the treated cancer cells areexposed to laser light, the photosensitizing agent absorbs the light andproduces an active form of oxygen that destroys the treated cancercells. Light exposure must be timed carefully so that it occurs whenmost of the photosensitizing agent has left healthy cells but is stillpresent in the cancer cells. The laser light used in PDT can be directedthrough a fiber-optic (a very thin glass strand). The fiber-optic isplaced close to the cancer to deliver the proper amount of light. Thefiber-optic can be directed through a bronchoscope into the lungs forthe treatment of lung cancer or through an endoscope into the esophagusfor the treatment of esophageal cancer. An advantage of PDT is that itcauses minimal damage to healthy tissue. However, because the laserlight currently in use cannot pass through more than about 3 centimetersof tissue (a little more than one and an eighth inch), PDT is mainlyused to treat tumors on or just under the skin or on the lining ofinternal organs. Photodynamic therapy makes the skin and eyes sensitiveto light for 6 weeks or more after treatment. Patients are advised toavoid direct sunlight and bright indoor light for at least 6 weeks. Ifpatients must go outdoors, they need to wear protective clothing,including sunglasses. Other temporary side effects of PDT are related tothe treatment of specific areas and can include coughing, troubleswallowing, abdominal pain, and painful breathing or shortness ofbreath. In December 1995, the U.S. Food and Drug Administration (FDA)approved a photosensitizing agent called porfimer sodium, or Photofrin®,to relieve symptoms of esophageal cancer that is causing an obstructionand for esophageal cancer that cannot be satisfactorily treated withlasers alone. In January 1998, the FDA approved porfimer sodium for thetreatment of early non-small cell lung cancer in patients for whom theusual treatments for lung cancer are not appropriate. The NationalCancer Institute and other institutions are supporting clinical trials(research studies) to evaluate the use of photodynamic therapy forseveral types of cancer, including cancers of the bladder, brain,larynx, and oral cavity.

In yet another embodiment, laser therapy is used to harnesshigh-intensity light to destroy cancer cells. This technique is oftenused to relieve symptoms of cancer such as bleeding or obstruction,especially when the cancer cannot be cured by other treatments. It mayalso be used to treat cancer by shrinking or destroying tumors. The term“laser” stands for light amplification by stimulated emission ofradiation. Ordinary light, such as that from a light bulb, has manywavelengths and spreads in all directions. Laser light, on the otherhand, has a specific wavelength and is focused in a narrow beam. Thistype of high-intensity light contains a lot of energy. Lasers are verypowerful and may be used to cut through steel or to shape diamonds.Lasers also can be used for very precise surgical work, such asrepairing a damaged retina in the eye or cutting through tissue (inplace of a scalpel). Although there are several different kinds oflasers, only three kinds have gained wide use in medicine: Carbondioxide (CO₂) laser—This type of laser can remove thin layers from theskin's surface without penetrating the deeper layers. This technique isparticularly useful in treating tumors that have not spread deep intothe skin and certain precancerous conditions. As an alternative totraditional scalpel surgery, the CO₂ laser is also able to cut the skin.The laser is used in this way to remove skin cancers.Neodymium:yttrium-aluminum-garnet (Nd:YAG) laser—Light from this lasercan penetrate deeper into tissue than light from the other types oflasers, and it can cause blood to clot quickly. It can be carriedthrough optical fibers to less accessible parts of the body. This typeof laser is sometimes used to treat throat cancers. Argon laser—Thislaser can pass through only superficial layers of tissue and istherefore useful in dermatology and in eye surgery. It also is used withlight-sensitive dyes to treat tumors in a procedure known asphotodynamic therapy (PDT). Lasers have several advantages over standardsurgical tools, including: Lasers are more precise than scalpels. Tissuenear an incision is protected, since there is little contact withsurrounding skin or other tissue. The heat produced by lasers sterilizesthe surgery site, thus reducing the risk of infection. Less operatingtime may be needed because the precision of the laser allows for asmaller incision. Healing time is often shortened; since laser heatseals blood vessels, there is less bleeding, swelling, or scarring.Laser surgery may be less complicated. For example, with fiber optics,laser light can be directed to parts of the body without making a largeincision. More procedures may be done on an outpatient basis. Lasers canbe used in two ways to treat cancer: by shrinking or destroying a tumorwith heat, or by activating a chemical—known as a photosensitizingagent—that destroys cancer cells. In PDT, a photosensitizing agent isretained in cancer cells and can be stimulated by light to cause areaction that kills cancer cells. CO₂ and Nd:YAG lasers are used toshrink or destroy tumors. They may be used with endoscopes, tubes thatallow physicians to see into certain areas of the body, such as thebladder. The light from some lasers can be transmitted through aflexible endoscope fitted with fiber optics. This allows physicians tosee and work in parts of the body that could not otherwise be reachedexcept by surgery and therefore allows very precise aiming of the laserbeam. Lasers also may be used with low-power microscopes, giving thedoctor a clear view of the site being treated. Used with otherinstruments, laser systems can produce a cutting area as small as 200microns in diameter—less than the width of a very fine thread. Lasersare used to treat many types of cancer. Laser surgery is a standardtreatment for certain stages of glottis (vocal cord), cervical, skin,lung, vaginal, vulvar, and penile cancers. In addition to its use todestroy the cancer, laser surgery is also used to help relieve symptomscaused by cancer (palliative care). For example, lasers may be used toshrink or destroy a tumor that is blocking a patient's trachea(windpipe), making it easier to breathe. It is also sometimes used forpalliation in colorectal and anal cancer. Laser-induced interstitialthermotherapy (LITT) is one of the most recent developments in lasertherapy. LITT uses the same idea as a cancer treatment calledhyperthermia; that heat may help shrink tumors by damaging cells ordepriving them of substances they need to live. In this treatment,lasers are directed to interstitial areas (areas between organs) in thebody. The laser light then raises the temperature of the tumor, whichdamages or destroys cancer cells.

The duration and/or dose of treatment with therapies may vary accordingto the particular therapeutic agent or combination thereof. Anappropriate treatment time for a particular cancer therapeutic agentwill be appreciated by the skilled artisan. The present inventioncontemplates the continued assessment of optimal treatment schedules foreach cancer therapeutic agent, where the phenotype of the cancer of thesubject as determined by the methods of the present invention is afactor in determining optimal treatment doses and schedules.

Any means for the introduction of a polynucleotide into mammals, humanor non-human, or cells thereof may be adapted to the practice of thisinvention for the delivery of the various constructs of the presentinvention into the intended recipient. In one embodiment of the presentinvention, the DNA constructs are delivered to cells by transfection,i.e., by delivery of “naked” DNA or in a complex with a colloidaldispersion system. A colloidal system includes macromolecule complexes,nanocapsules, microspheres, beads, and lipid-based systems includingoil-in-water emulsions, micelles, mixed micelles, and liposomes. Thepreferred colloidal system of this invention is a lipid-complexed orliposome-formulated DNA. In the former approach, prior to formulation ofDNA, e.g., with lipid, a plasmid containing a transgene bearing thedesired DNA constructs may first be experimentally optimized forexpression (e.g., inclusion of an intron in the 5′ untranslated regionand elimination of unnecessary sequences (Felgner, et al., Ann NY AcadSci 126-139, 1995). Formulation of DNA, e.g. with various lipid orliposome materials, may then be effected using known methods andmaterials and delivered to the recipient mammal. See, e.g., Canonico etal, Am J Respir Cell Mol Biol 10:24-29, 1994; Tsan et al, Am J Physiol268; Alton et al., Nat Genet. 5:135-142, 1993 and U.S. Pat. No.5,679,647 by Carson et al.

The targeting of liposomes can be classified based on anatomical andmechanistic factors. Anatomical classification is based on the level ofselectivity, for example, organ-specific, cell-specific, andorganelle-specific. Mechanistic targeting can be distinguished basedupon whether it is passive or active. Passive targeting utilizes thenatural tendency of liposomes to distribute to cells of thereticulo-endothelial system (RES) in organs, which contain sinusoidalcapillaries. Active targeting, on the other hand, involves alteration ofthe liposome by coupling the liposome to a specific ligand such as amonoclonal antibody, sugar, glycolipid, or protein, or by changing thecomposition or size of the liposome in order to achieve targeting toorgans and cell types other than the naturally occurring sites oflocalization.

The surface of the targeted delivery system may be modified in a varietyof ways. In the case of a liposomal targeted delivery system, lipidgroups can be incorporated into the lipid bilayer of the liposome inorder to maintain the targeting ligand in stable association with theliposomal bilayer. Various linking groups can be used for joining thelipid chains to the targeting ligand. Naked DNA or DNA associated with adelivery vehicle, e.g., liposomes, can be administered to several sitesin a subject (see below).

Nucleic acids can be delivered in any desired vector. These includeviral or non-viral vectors, including adenovirus vectors,adeno-associated virus vectors, retrovirus vectors, lentivirus vectors,and plasmid vectors. Exemplary types of viruses include HSV (herpessimplex virus), AAV (adeno associated virus), HIV (humanimmunodeficiency virus), BIV (bovine immunodeficiency virus), and MLV(murine leukemia virus). Nucleic acids can be administered in anydesired format that provides sufficiently efficient delivery levels,including in virus particles, in liposomes, in nanoparticles, andcomplexed to polymers.

The nucleic acids encoding a protein or nucleic acid of interest may bein a plasmid or viral vector, or other vector as is known in the art.Such vectors are well-known and any can be selected for a particularapplication. In one embodiment of the present invention, the genedelivery vehicle comprises a promoter and a demethylase coding sequence.Preferred promoters are tissue-specific promoters and promoters whichare activated by cellular proliferation, such as the thymidine kinaseand thymidylate synthase promoters. Other preferred promoters includepromoters which are activatable by infection with a virus, such as theα- and β-interferon promoters, and promoters which are activatable by ahormone, such as estrogen. Other promoters which can be used include theMoloney virus LTR, the CMV promoter, and the mouse albumin promoter. Apromoter may be constitutive or inducible.

In another embodiment, naked polynucleotide molecules are used as genedelivery vehicles, as described in WO 90/11092 and U.S. Pat. No.5,580,859. Such gene delivery vehicles can be either growth factor DNAor RNA and, in certain embodiments, are linked to killed adenovirus.Curiel et al., Hum. Gene. Ther. 3:147-154, 1992. Other vehicles whichcan optionally be used include DNA-ligand (Wu et al., J. Biol. Chem.264:16985-16987, 1989), lipid-DNA combinations (Felgner et al., Proc.Natl. Acad. Sci. USA 84:7413 7417, 1989), liposomes (Wang et al., Proc.Natl. Acad. Sci. 84:7851-7855, 1987) and microprojectiles (Williams etal., Proc. Natl. Acad. Sci. 88:2726-2730, 1991).

A gene delivery vehicle can optionally comprise viral sequences such asa viral origin of replication or packaging signal. These viral sequencescan be selected from viruses such as astrovirus, coronavirus,orthomyxovirus, papovavirus, paramyxovirus, parvovirus, picornavirus,poxvirus, retrovirus, togavirus or adenovirus. In a preferredembodiment, the growth factor gene delivery vehicle is a recombinantretroviral vector. Recombinant retroviruses and various uses thereofhave been described in numerous references including, for example, Mannet al., Cell 33:153, 1983, Cane and Mulligan, Proc. Nat'l. Acad. Sci.USA 81:6349, 1984, Miller et al., Human Gene Therapy 1:5-14, 1990, U.S.Pat. Nos. 4,405,712, 4,861,719, and 4,980,289, and PCT Application Nos.WO 89/02,468, WO 89/05,349, and WO 90/02,806. Numerous retroviral genedelivery vehicles can be utilized in the present invention, includingfor example those described in EP 0,415,731; WO 90/07936; WO 94/03622;WO 93/25698; WO 93/25234; U.S. Pat. No. 5,219,740; WO 9311230; WO9310218; Vile and Hart, Cancer Res. 53:3860-3864, 1993; Vile and Hart,Cancer Res. 53:962-967, 1993; Ram et al., Cancer Res. 53:83-88, 1993;Takamiya et al., J. Neurosci. Res. 33:493-503, 1992; Baba et al., J.Neurosurg. 79:729-735, 1993 (U.S. Pat. No. 4,777,127, GB 2,200,651, EP0,345,242 and WO91/02805).

VI. Clinical Efficacy

Clinical efficacy can be measured by any method known in the art. Forexample, the response to a therapy, such as modulators of the genomicand/or epigenomic alterations of biomarkers described herein, relates toany response of the cancer, e.g., a tumor, to the therapy, preferably toa change in tumor mass and/or volume after initiation of neoadjuvant oradjuvant chemotherapy. Tumor response may be assessed in a neoadjuvantor adjuvant situation where the size of a tumor after systemicintervention can be compared to the initial size and dimensions asmeasured by CT, PET, mammogram, ultrasound or palpation and thecellularity of a tumor can be estimated histologically and compared tothe cellularity of a tumor biopsy taken before initiation of treatment.Response may also be assessed by caliper measurement or pathologicalexamination of the tumor after biopsy or surgical resection. Responsemay be recorded in a quantitative fashion like percentage change intumor volume or cellularity or using a semi-quantitative scoring systemsuch as residual cancer burden (Symmans et al., J. Clin. Oncol. (2007)25:4414-4422) or Miller-Payne score (Ogston et al., (2003) Breast(Edinburgh, Scotland) 12:320-327) in a qualitative fashion like“pathological complete response” (pCR), “clinical complete remission”(cCR), “clinical partial remission” (cPR), “clinical stable disease”(cSD), “clinical progressive disease” (cPD) or other qualitativecriteria. Assessment of tumor response may be performed early after theonset of neoadjuvant or adjuvant therapy, e.g., after a few hours, days,weeks or preferably after a few months. A typical endpoint for responseassessment is upon termination of neoadjuvant chemotherapy or uponsurgical removal of residual tumor cells and/or the tumor bed.

In some embodiments, clinical efficacy of the therapeutic treatmentsdescribed herein may be determined by measuring the clinical benefitrate (CBR). The clinical benefit rate is measured by determining the sumof the percentage of patients who are in complete remission (CR), thenumber of patients who are in partial remission (PR) and the number ofpatients having stable disease (SD) at a time point at least 6 monthsout from the end of therapy. The shorthand for this formula isCBR=CR+PR+SD over 6 months. In some embodiments, the CBR for aparticular anti-immune checkpoint therapeutic regimen is at least 25%,30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, or more.

Additional criteria for evaluating the response to immunotherapies, suchas anti-immune checkpoint therapies, are related to “survival,” whichincludes all of the following: survival until mortality, also known asoverall survival (wherein said mortality may be either irrespective ofcause or tumor related); “recurrence-free survival” (wherein the termrecurrence shall include both localized and distant recurrence);metastasis free survival; disease free survival (wherein the termdisease shall include cancer and diseases associated therewith). Thelength of said survival may be calculated by reference to a definedstart point (e.g., time of diagnosis or start of treatment) and endpoint (e.g., death, recurrence or metastasis). In addition, criteria forefficacy of treatment can be expanded to include response tochemotherapy, probability of survival, probability of metastasis withina given time period, and probability of tumor recurrence.

For example, in order to determine appropriate threshold values, aparticular anti-cancer therapeutic regimen can be administered to apopulation of subjects and the outcome can be correlated to biomarkermeasurements that were determined prior to administration of anyimmunotherapy, such as anti-immune checkpoint therapy. The outcomemeasurement may be pathologic response to therapy given in theneoadjuvant setting. Alternatively, outcome measures, such as overallsurvival and disease-free survival can be monitored over a period oftime for subjects following immunotherapies for whom biomarkermeasurement values are known. In certain embodiments, the same doses ofimmunotherapy agents, if any, are administered to each subject. Inrelated embodiments, the doses administered are standard doses known inthe art for those agents used in immunotherapies. The period of time forwhich subjects are monitored can vary. For example, subjects may bemonitored for at least 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 25, 30, 35,40, 45, 50, 55, or 60 months. Biomarker measurement threshold valuesthat correlate to outcome of an immunotherapy can be determined usingmethods such as those described in the Examples section.

VII. Further Uses and Methods of the Present Invention

The compositions described herein can be used in a variety ofdiagnostic, prognostic, and therapeutic applications. In any methoddescribed herein, such as a diagnostic method, prognostic method,therapeutic method, or combination thereof, all steps of the method canbe performed by a single actor or, alternatively, by more than oneactor. For example, diagnosis can be performed directly by the actorproviding therapeutic treatment. Alternatively, a person providing atherapeutic agent can request that a diagnostic assay be performed. Thediagnostician and/or the therapeutic interventionist can interpret thediagnostic assay results to determine a therapeutic strategy. Similarly,such alternative processes can apply to other assays, such as prognosticassays.

a. Screening Methods

One aspect of the present invention relates to screening assays,including non-cell based assays and xenograft animal model assays.

In one embodiment, the present invention relates to assays for screeningtest agents which modulate the genomic and/or epigenomic alteration(s)of, at least one biomarker described herein (e.g., in the tables,figures, examples, or otherwise in the specification). In oneembodiment, a method for identifying such an agent entails determiningthe ability of the agent to modulate, the genomic and/or epigenomicalteration(s) of, at least one biomarker described herein.

In one embodiment, an assay is a cell-free or cell-based assay,comprising contacting at least one biomarker described herein, with atest agent, and determining the ability of the test agent to modulatethe genomic and/or epigenomic alteration(s) of the biomarker, such as bymeasuring direct genomic and/or epigenomic alteration(s) of thebiomarker or by measuring indirect parameters (e.g., by measuring mRNAexpression, protein expression, and/or activity of the biomarker, and/orbinding of the biomarker to its substrates).

The present invention further pertains to novel agents identified by theabove-described screening assays. Accordingly, it is within the scope ofthis invention to further use an agent identified as described herein,such as in an appropriate animal model. For example, an agent identifiedas described herein can be used in an animal model to determine theefficacy, toxicity, or side effects of treatment with such an agent.Alternatively, an antibody identified as described herein can be used inan animal model to determine the mechanism of action of such an agent.

b. Predictive Medicine

The present invention also pertains to the field of predictive medicinein which diagnostic assays, prognostic assays, and monitoring clinicaltrials are used for prognostic (predictive) purposes to thereby treat anindividual prophylactically. Accordingly, one aspect of the presentinvention relates to diagnostic assays for determining the genmic and/orepigenomic alterations of a biomarker described herein in the context ofa biological sample (e.g., blood, serum, cells, or tissue) to therebydetermine whether an individual afflicted with castration-resistantneuroendocrine prosate cancer (CRPC-NE) or at risk for developingCRPC-NE. Such assays can be used for prognostic or predictive purposealone, or can be coupled with a therapeutic intervention to therebyprophylactically treat an individual prior to the onset or afterrecurrence of a disorder characterized by or associated with biomarkergenmic and/or epigenomic alterations. The skilled artisan willappreciate that any method can use one or more (e.g., combinations) ofbiomarkers described herein, such as those in the tables, figures,examples, and otherwise described in the specification.

Another aspect of the present invention pertains to monitoring theinfluence of agents (e.g., drugs, compounds, and small nucleicacid-based molecules) on genmic and/or epigenomic alterations of abiomarker described herein. These and other agents are described infurther detail in the following sections.

The skilled artisan will also appreciated that, in certain embodiments,the methods of the present invention implement a computer program andcomputer system. For example, a computer program can be used to performthe algorithms described herein. A computer system can also store andmanipulate data generated by the methods of the present invention whichcomprises a plurality of biomarker signal changes/profiles which can beused by a computer system in implementing the methods of this invention.In certain embodiments, a computer system receives biomarker expressiondata; (ii) stores the data; and (iii) compares the data in any number ofways described herein (e.g., analysis relative to appropriate controls)to determine the state of informative biomarkers from cancerous orpre-cancerous tissue. In other embodiments, a computer system (i)compares the determined expression biomarker level to a threshold value;and (ii) outputs an indication of whether said biomarker level issignificantly modulated (e.g., above or below) the threshold value, or aphenotype based on said indication.

In certain embodiments, such computer systems are also considered partof the present invention. Numerous types of computer systems can be usedto implement the analytic methods of this invention according toknowledge possessed by a skilled artisan in the bioinformatics and/orcomputer arts. Several software components can be loaded into memoryduring operation of such a computer system. The software components cancomprise both software components that are standard in the art andcomponents that are special to the present invention (e.g., dCHIPsoftware described in Lin et al. (2004) Bioinformatics 20, 1233-1240;radial basis machine learning algorithms (RBM) known in the art).

The methods of the present invention can also be programmed or modeledin mathematical software packages that allow symbolic entry of equationsand high-level specification of processing, including specificalgorithms to be used, thereby freeing a user of the need toprocedurally program individual equations and algorithms. Such packagesinclude, e.g., Matlab from Mathworks (Natick, Mass.), Mathematica fromWolfram Research (Champaign, Ill.) or S-Plus from MathSoft (Seattle,Wash.).

In certain embodiments, the computer comprises a database for storage ofbiomarker data. Such stored profiles can be accessed and used to performcomparisons of interest at a later point in time. For example, biomarkerexpression profiles of a sample derived from the non-cancerous tissue ofa subject and/or profiles generated from population-based distributionsof informative loci of interest in relevant populations of the samespecies can be stored and later compared to that of a sample derivedfrom the cancerous tissue of the subject or tissue suspected of beingcancerous of the subject.

In addition to the exemplary program structures and computer systemsdescribed herein, other, alternative program structures and computersystems will be readily apparent to the skilled artisan. Suchalternative systems, which do not depart from the above describedcomputer system and programs structures either in spirit or in scope,are therefore intended to be comprehended within the accompanyingclaims.

c. Diagnostic Assays

The present invention provides, in part, methods, systems, and code foraccurately classifying whether a biological sample (e.g., from asubject) is associated with castration-resistant neuroendocrine prosatecancer (CRPC-NE). In some embodiments, the present invention is usefulfor classifying a subject as associated with or at risk for developingcastration-resistant neuroendocrine prosate cancer (CRPC-NE).

An exemplary method for detecting the genomic and/or epigenomicalterations of a biomarker described herein, and thus useful forclassifying whether a subject is afflicted with castration-resistantneuroendocrine prosate cancer (CRPC-NE) or at risk for developingCRPC-NE. In certain instances, a neuroendocrine prostate cancer (NEPC)score is computed based on the presence or absence of one or moregenomic or epigenomic alterations of the biomarkers described herein. Incertain instances, the statistical algorithm is a single learningstatistical classifier system. For example, a single learningstatistical classifier system can be used to classify a subject asassociated with or at risk for developing castration-resistantneuroendocrine prosate cancer (CRPC-NE) based upon a prediction orprobability value and the presence or level of the genomic and/orepigenomic alterations of the biomarker. The use of a single learningstatistical classifier system typically classifies the subject as, forexample, associated with or at risk for developing castration-resistantneuroendocrine prosate cancer (CRPC-NE) with a sensitivity, specificity,positive predictive value, negative predictive value, and/or overallaccuracy of at least about 75%, 76%, 77%, 78%, 79%, 80%, 81%, 82%, 83%,84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%,98%, or 99%.

Other suitable statistical algorithms are well-known to those of skillin the art. For example, learning statistical classifier systems includea machine learning algorithmic technique capable of adapting to complexdata sets (e.g., panel of markers of interest) and making decisionsbased upon such data sets. In some embodiments, a single learningstatistical classifier system such as a classification tree (e.g.,random forest) is used. In other embodiments, a combination of 2, 3, 4,5, 6, 7, 8, 9, 10, or more learning statistical classifier systems areused, preferably in tandem. Examples of learning statistical classifiersystems include, but are not limited to, those using inductive learning(e.g., decision/classification trees such as random forests,classification and regression trees (C&RT), boosted trees, etc.),Probably Approximately Correct (PAC) learning, connectionist learning(e.g., neural networks (NN), artificial neural networks (ANN), neurofuzzy networks (NFN), network structures, perceptrons such asmulti-layer perceptrons, multi-layer feed-forward networks, applicationsof neural networks, Bayesian learning in belief networks, etc.),reinforcement learning (e.g., passive learning in a known environmentsuch as naive learning, adaptive dynamic learning, and temporaldifference learning, passive learning in an unknown environment, activelearning in an unknown environment, learning action-value functions,applications of reinforcement learning, etc.), and genetic algorithmsand evolutionary programming. Other learning statistical classifiersystems include support vector machines (e.g., Kernel methods),multivariate adaptive regression splines (MARS), Levenberg-Marquardtalgorithms, Gauss-Newton algorithms, mixtures of Gaussians, gradientdescent algorithms, and learning vector quantization (LVQ). In certainembodiments, the method of the present invention further comprisessending the sample classification results to a clinician, e.g., anoncologist.

In another embodiment, the diagnosis of a subject is followed byadministering to the individual a therapeutically effective amount of adefined treatment based upon the diagnosis. For example, in oneembodiment, the subject is administered with an anti-cancer therapy(e.g., platinum-based chemotherapy) other than an AR-targeted therapy asa single agent if the subject is afflicted with CRPC-NE or at risk fordeveloping CRPC-NE. In another embodiment, the subject is administeredwith an AR-targeted therapy if the subject is not afflicted with CRPC-NEor not at risk for developing CRPC-NE. The anti-cancer therapy isselected from the group consisting of an epgenitic modifier, targetedtherapy, chemotherapy, radiation therapy, and/or hormonal therapy,optionally wherein the anti-cancer therapy comprises an AR-targetedtherapy.

In one embodiment, the methods further involve obtaining a controlbiological sample (e.g., biological sample from a subject who does nothave a prostate cancer or have castration resistant prostateadenocarcinoma (CRPC-Adeno)), a biological sample from the subjectduring remission, or a biological sample from the subject duringtreatment for developing a cancer progressing despite treatments withmodulators of biomarker genomic and/or epigenomic alterations.

d. Prognostic Assays

The diagnostic methods described herein can furthermore be utilized toidentify subjects having or at risk of developing CRPC-NE that is likelyor unlikely to be responsive to modulators of biomarker genomic and/orepigenomic alterations. The assays described herein, such as thepreceding diagnostic assays or the following assays, can be utilized toidentify a subject having or at risk of developing a disorder associatedwith a misregulation of the genomic and/or epigenomic features of atleast one biomarker described herein, such as in cancer. Alternatively,the prognostic assays can be utilized to identify a subject having or atrisk for developing a disorder associated with a misregulation of thegenomic and/or epigenomic features of at least one biomarker describedherein, such as in cancer. Furthermore, the prognostic assays describedherein can be used to determine whether a subject can be administered anagent (e.g., an agonist, antagonist, peptidomimetic, polypeptide,peptide, nucleic acid, small molecule, an epigenetic modifier, or otherdrug candidate) to treat a disease or disorder associated with theaberrant biomarker genomic and/or epigenomic features.

e. Treatment Methods

The therapeutic compositions described herein, such as agents modulatinggenomic and/or epigenomic alterations of biomarkers described herein,can be used in a variety of in vitro and in vivo therapeuticapplications using the formulations and/or combinations describedherein. In one embodiment, the therapeutic agents can be used to treatCRPC-NE cancer. For example, single or multiple agents that modulategenomic and/or epigenomic alterations of a biomarker alone or incombination with an additional anti-cancer therapy (e.g., chemotherapy,immunotherapy, or AR-targeted therapy) can be used to treat cancers insubjects identified as having or at the risk of developing CRPC-NE.

VIII. Administration of Agents

In another aspect, the present invention provides pharmaceuticallyacceptable compositions which comprise a therapeutically-effectiveamount of an agent that modulates biomarker genomic and/or epigenmicalterations described herein, formulated together with one or morepharmaceutically acceptable carriers (additives) and/or diluents. Asdescribed in detail below, the pharmaceutical compositions of thepresent invention may be specially formulated for administration insolid or liquid form, including those adapted for the following: (1)oral administration, for example, drenches (aqueous or non-aqueoussolutions or suspensions), tablets, boluses, powders, granules, pastes;(2) parenteral administration, for example, by subcutaneous,intramuscular or intravenous injection as, for example, a sterilesolution or suspension; (3) topical application, for example, as acream, ointment or spray applied to the skin; (4) intravaginally orintrarectally, for example, as a pessary, cream or foam; or (5) aerosol,for example, as an aqueous aerosol, liposomal preparation or solidparticles containing the compound.

The phrase “therapeutically-effective amount” as used herein means thatamount of an agent that modulates (e.g., inhibits) biomarker expressionand/or activity, or expression and/or activity of the complex, orcomposition comprising an agent that modulates (e.g., inhibits)biomarker expression and/or activity, or expression and/or activity ofthe complex, which is effective for producing some desired therapeuticeffect, e.g., cancer treatment, at a reasonable benefit/risk ratio.

The phrase “pharmaceutically acceptable” is employed herein to refer tothose agents, materials, compositions, and/or dosage forms which are,within the scope of sound medical judgment, suitable for use in contactwith the tissues of human beings and animals without excessive toxicity,irritation, allergic response, or other problem or complication,commensurate with a reasonable benefit/risk ratio.

The phrase “pharmaceutically-acceptable carrier” as used herein means apharmaceutically-acceptable material, composition or vehicle, such as aliquid or solid filler, diluent, excipient, solvent or encapsulatingmaterial, involved in carrying or transporting the subject chemical fromone organ, or portion of the body, to another organ, or portion of thebody. Each carrier must be “acceptable” in the sense of being compatiblewith the other ingredients of the formulation and not injurious to thesubject. Some examples of materials which can serve aspharmaceutically-acceptable carriers include: (1) sugars, such aslactose, glucose and sucrose; (2) starches, such as corn starch andpotato starch; (3) cellulose, and its derivatives, such as sodiumcarboxymethyl cellulose, ethyl cellulose and cellulose acetate; (4)powdered tragacanth; (5) malt; (6) gelatin; (7) talc; (8) excipients,such as cocoa butter and suppository waxes; (9) oils, such as peanutoil, cottonseed oil, safflower oil, sesame oil, olive oil, corn oil andsoybean oil; (10) glycols, such as propylene glycol; (11) polyols, suchas glycerin, sorbitol, mannitol and polyethylene glycol; (12) esters,such as ethyl oleate and ethyl laurate; (13) agar; (14) bufferingagents, such as magnesium hydroxide and aluminum hydroxide; (15) alginicacid; (16) pyrogen-free water; (17) isotonic saline; (18) Ringer'ssolution; (19) ethyl alcohol; (20) phosphate buffer solutions; and (21)other non-toxic compatible substances employed in pharmaceuticalformulations.

The term “pharmaceutically-acceptable salts” refers to the relativelynon-toxic, inorganic and organic acid addition salts of the agents thatmodulates (e.g., inhibits) biomarker expression and/or activity, orexpression and/or activity of the complex encompassed by the presentinvention. These salts can be prepared in situ during the finalisolation and purification of the agents, or by separately reacting apurified agent in its free base form with a suitable organic orinorganic acid, and isolating the salt thus formed. ReRepresentativesalts include the hydrobromide, hydrochloride, sulfate, bisulfate,phosphate, nitrate, acetate, valerate, oleate, palmitate, stearate,laurate, benzoate, lactate, phosphate, tosylate, citrate, maleate,fumarate, succinate, tartrate, napthylate, mesylate, glucoheptonate,lactobionate, and laurylsulphonate salts and the like (See, for example,Berge et al. (1977) “Pharmaceutical Salts”, J. Pharm. Sci. 66:1-19).

In other cases, the agents useful in the methods of the presentinvention may contain one or more acidic functional groups and, thus,are capable of forming pharmaceutically-acceptable salts withpharmaceutically-acceptable bases. The term “pharmaceutically-acceptablesalts” in these instances refers to the relatively non-toxic, inorganicand organic base addition salts of agents that modulates (e.g.,inhibits) biomarker expression and/or activity, or expression and/oractivity of the complex. These salts can likewise be prepared in situduring the final isolation and purification of the agents, or byseparately reacting the purified agent in its free acid form with asuitable base, such as the hydroxide, carbonate or bicarbonate of apharmaceutically-acceptable metal cation, with ammonia, or with apharmaceutically-acceptable organic primary, secondary or tertiaryamine. ReRepresentative alkali or alkaline earth salts include thelithium, sodium, potassium, calcium, magnesium, and aluminum salts andthe like. ReRepresentative organic amines useful for the formation ofbase addition salts include ethylamine, diethylamine, ethylenediamine,ethanolamine, diethanolamine, piperazine and the like (see, for example,Berge et al., supra).

Wetting agents, emulsifiers and lubricants, such as sodium laurylsulfate and magnesium stearate, as well as coloring agents, releaseagents, coating agents, sweetening, flavoring and perfuming agents,preservatives and antioxidants can also be present in the compositions.

Examples of pharmaceutically-acceptable antioxidants include: (1) watersoluble antioxidants, such as ascorbic acid, cysteine hydrochloride,sodium bisulfate, sodium metabisulfite, sodium sulfite and the like; (2)oil-soluble antioxidants, such as ascorbyl palmitate, butylatedhydroxyanisole (BHA), butylated hydroxytoluene (BHT), lecithin, propylgallate, alpha-tocopherol, and the like; and (3) metal chelating agents,such as citric acid, ethylenediamine tetraacetic acid (EDTA), sorbitol,tartaric acid, phosphoric acid, and the like.

Formulations useful in the methods of the present invention includethose suitable for oral, nasal, topical (including buccal andsublingual), rectal, vaginal, aerosol and/or parenteral administration.The formulations may conveniently be presented in unit dosage form andmay be prepared by any methods well known in the art of pharmacy. Theamount of active ingredient which can be combined with a carriermaterial to produce a single dosage form will vary depending upon thehost being treated, the particular mode of administration. The amount ofactive ingredient, which can be combined with a carrier material toproduce a single dosage form will generally be that amount of thecompound which produces a therapeutic effect. Generally, out of onehundred percent, this amount will range from about 1 percent to aboutninety-nine percent of active ingredient, preferably from about 5percent to about 70 percent, most preferably from about 10 percent toabout 30 percent.

Methods of preparing these formulations or compositions include the stepof bringing into association an agent that modulates (e.g., inhibits)biomarker expression and/or activity, with the carrier and, optionally,one or more accessory ingredients. In general, the formulations areprepared by uniformly and intimately bringing into association a agentwith liquid carriers, or finely divided solid carriers, or both, andthen, if necessary, shaping the product.

Formulations suitable for oral administration may be in the form ofcapsules, cachets, pills, tablets, lozenges (using a flavored basis,usually sucrose and acacia or tragacanth), powders, granules, or as asolution or a suspension in an aqueous or non-aqueous liquid, or as anoil-in-water or water-in-oil liquid emulsion, or as an elixir or syrup,or as pastilles (using an inert base, such as gelatin and glycerin, orsucrose and acacia) and/or as mouth washes and the like, each containinga predetermined amount of a agent as an active ingredient. A compoundmay also be administered as a bolus, electuary or paste.

In solid dosage forms for oral administration (capsules, tablets, pills,dragees, powders, granules and the like), the active ingredient is mixedwith one or more pharmaceutically-acceptable carriers, such as sodiumcitrate or dicalcium phosphate, and/or any of the following: (1) fillersor extenders, such as starches, lactose, sucrose, glucose, mannitol,and/or silicic acid; (2) binders, such as, for example,carboxymethylcellulose, alginates, gelatin, polyvinyl pyrrolidone,sucrose and/or acacia; (3) humectants, such as glycerol; (4)disintegrating agents, such as agar-agar, calcium carbonate, potato ortapioca starch, alginic acid, certain silicates, and sodium carbonate;(5) solution retarding agents, such as paraffin; (6) absorptionaccelerators, such as quaternary ammonium compounds; (7) wetting agents,such as, for example, acetyl alcohol and glycerol monostearate; (8)absorbents, such as kaolin and bentonite clay; (9) lubricants, such atalc, calcium stearate, magnesium stearate, solid polyethylene glycols,sodium lauryl sulfate, and mixtures thereof; and (10) coloring agents.In the case of capsules, tablets and pills, the pharmaceuticalcompositions may also comprise buffering agents. Solid compositions of asimilar type may also be employed as fillers in soft and hard-filledgelatin capsules using such excipients as lactose or milk sugars, aswell as high molecular weight polyethylene glycols and the like.

A tablet may be made by compression or molding, optionally with one ormore accessory ingredients. Compressed tablets may be prepared usingbinder (for example, gelatin or hydroxypropylmethyl cellulose),lubricant, inert diluent, preservative, disintegrant (for example,sodium starch glycolate or cross-linked sodium carboxymethyl cellulose),surface-active or dispersing agent. Molded tablets may be made bymolding in a suitable machine a mixture of the powdered peptide orpeptidomimetic moistened with an inert liquid diluent.

Tablets, and other solid dosage forms, such as dragees, capsules, pillsand granules, may optionally be scored or prepared with coatings andshells, such as enteric coatings and other coatings well known in thepharmaceutical-formulating art. They may also be formulated so as toprovide slow or controlled release of the active ingredient thereinusing, for example, hydroxypropylmethyl cellulose in varying proportionsto provide the desired release profile, other polymer matrices,liposomes and/or microspheres. They may be sterilized by, for example,filtration through a bacteria-retaining filter, or by incorporatingsterilizing agents in the form of sterile solid compositions, which canbe dissolved in sterile water, or some other sterile injectable mediumimmediately before use. These compositions may also optionally containopacifying agents and may be of a composition that they release theactive ingredient(s) only, or preferentially, in a certain portion ofthe gastrointestinal tract, optionally, in a delayed manner. Examples ofembedding compositions, which can be used include polymeric substancesand waxes. The active ingredient can also be in micro-encapsulated form,if appropriate, with one or more of the above-described excipients.

Liquid dosage forms for oral administration include pharmaceuticallyacceptable emulsions, microemulsions, solutions, suspensions, syrups andelixirs. In addition to the active ingredient, the liquid dosage formsmay contain inert diluents commonly used in the art, such as, forexample, water or other solvents, solubilizing agents and emulsifiers,such as ethyl alcohol, isopropyl alcohol, ethyl carbonate, ethylacetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3-butyleneglycol, oils (in particular, cottonseed, groundnut, corn, germ, olive,castor and sesame oils), glycerol, tetrahydrofuryl alcohol, polyethyleneglycols and fatty acid esters of sorbitan, and mixtures thereof.

Besides inert diluents, the oral compositions can also include adjuvantssuch as wetting agents, emulsifying and suspending agents, sweetening,flavoring, coloring, perfuming and preservative agents.

Suspensions, in addition to the active agent may contain suspendingagents as, for example, ethoxylated isostearyl alcohols, polyoxyethylenesorbitol and sorbitan esters, microcrystalline cellulose, aluminummetahydroxide, bentonite, agar-agar and tragacanth, and mixturesthereof.

Formulations for rectal or vaginal administration may be presented as asuppository, which may be prepared by mixing one or more agents with oneor more suitable nonirritating excipients or carriers comprising, forexample, cocoa butter, polyethylene glycol, a suppository wax or asalicylate, and which is solid at room temperature, but liquid at bodytemperature and, therefore, will melt in the rectum or vaginal cavityand release the active agent.

Formulations which are suitable for vaginal administration also includepessaries, tampons, creams, gels, pastes, foams or spray formulationscontaining such carriers as are known in the art to be appropriate.

Dosage forms for the topical or transdermal administration of an agentthat modulates (e.g., inhibits) biomarker expression and/or activityinclude powders, sprays, ointments, pastes, creams, lotions, gels,solutions, patches and inhalants. The active component may be mixedunder sterile conditions with a pharmaceutically-acceptable carrier, andwith any preservatives, buffers, or propellants which may be required.

The ointments, pastes, creams and gels may contain, in addition to aagent, excipients, such as animal and vegetable fats, oils, waxes,paraffins, starch, tragacanth, cellulose derivatives, polyethyleneglycols, silicones, bentonites, silicic acid, talc and zinc oxide, ormixtures thereof.

Powders and sprays can contain, in addition to an agent that modulates(e.g., inhibits) biomarker expression and/or activity, excipients suchas lactose, talc, silicic acid, aluminum hydroxide, calcium silicatesand polyamide powder, or mixtures of these substances. Sprays canadditionally contain customary propellants, such aschlorofluorohydrocarbons and volatile unsubstituted hydrocarbons, suchas butane and propane.

The agent that modulates (e.g., inhibits) biomarker expression and/oractivity, can be alternatively administered by aerosol. This isaccomplished by preparing an aqueous aerosol, liposomal preparation orsolid particles containing the compound. A nonaqueous (e.g.,fluorocarbon propellant) suspension could be used. Sonic nebulizers arepreferred because they minimize exposing the agent to shear, which canresult in degradation of the compound.

Ordinarily, an aqueous aerosol is made by formulating an aqueoussolution or suspension of the agent together with conventionalpharmaceutically acceptable carriers and stabilizers. The carriers andstabilizers vary with the requirements of the particular compound, buttypically include nonionic surfactants (Tweens, Pluronics, orpolyethylene glycol), innocuous proteins like serum albumin, sorbitanesters, oleic acid, lecithin, amino acids such as glycine, buffers,salts, sugars or sugar alcohols. Aerosols generally are prepared fromisotonic solutions.

Transdermal patches have the added advantage of providing controlleddelivery of a agent to the body. Such dosage forms can be made bydissolving or dispersing the agent in the proper medium. Absorptionenhancers can also be used to increase the flux of the peptidomimeticacross the skin. The rate of such flux can be controlled by eitherproviding a rate controlling membrane or dispersing the peptidomimeticin a polymer matrix or gel.

Ophthalmic formulations, eye ointments, powders, solutions and the like,are also contemplated as being within the scope of this invention.

Pharmaceutical compositions of this invention suitable for parenteraladministration comprise one or more agents in combination with one ormore pharmaceutically-acceptable sterile isotonic aqueous or nonaqueoussolutions, dispersions, suspensions or emulsions, or sterile powderswhich may be reconstituted into sterile injectable solutions ordispersions just prior to use, which may contain antioxidants, buffers,bacteriostats, solutes which render the formulation isotonic with theblood of the intended recipient or suspending or thickening agents.

Examples of suitable aqueous and nonaqueous carriers which may beemployed in the pharmaceutical compositions of the present inventioninclude water, ethanol, polyols (such as glycerol, propylene glycol,polyethylene glycol, and the like), and suitable mixtures thereof,vegetable oils, such as olive oil, and injectable organic esters, suchas ethyl oleate. Proper fluidity can be maintained, for example, by theuse of coating materials, such as lecithin, by the maintenance of therequired particle size in the case of dispersions, and by the use ofsurfactants.

These compositions may also contain adjuvants such as preservatives,wetting agents, emulsifying agents and dispersing agents. Prevention ofthe action of microorganisms may be ensured by the inclusion of variousantibacterial and antifungal agents, for example, paraben,chlorobutanol, phenol sorbic acid, and the like. It may also bedesirable to include isotonic agents, such as sugars, sodium chloride,and the like into the compositions. In addition, prolonged absorption ofthe injectable pharmaceutical form may be brought about by the inclusionof agents which delay absorption such as aluminum monostearate andgelatin.

In some cases, in order to prolong the effect of a drug, it is desirableto slow the absorption of the drug from subcutaneous or intramuscularinjection. This may be accomplished by the use of a liquid suspension ofcrystalline or amorphous material having poor water solubility. The rateof absorption of the drug then depends upon its rate of dissolution,which, in turn, may depend upon crystal size and crystalline form.Alternatively, delayed absorption of a parenterally-administered drugform is accomplished by dissolving or suspending the drug in an oilvehicle.

Injectable depot forms are made by forming microencapsule matrices of anagent that modulates (e.g., inhibits) biomarker expression and/oractivity, in biodegradable polymers such as polylactide-polyglycolide.Depending on the ratio of drug to polymer, and the nature of theparticular polymer employed, the rate of drug release can be controlled.Examples of other biodegradable polymers include poly(orthoesters) andpoly(anhydrides). Depot injectable formulations are also prepared byentrapping the drug in liposomes or microemulsions, which are compatiblewith body tissue.

When the agents of the present invention are administered aspharmaceuticals, to humans and animals, they can be given per se or as apharmaceutical composition containing, for example, 0.1 to 99.5% (morepreferably, 0.5 to 90%) of active ingredient in combination with apharmaceutically acceptable carrier.

Actual dosage levels of the active ingredients in the pharmaceuticalcompositions of this invention may be determined by the methods of thepresent invention so as to obtain an amount of the active ingredient,which is effective to achieve the desired therapeutic response for aparticular subject, composition, and mode of administration, withoutbeing toxic to the subject.

The nucleic acid molecules of the present invention can be inserted intovectors and used as gene therapy vectors. Gene therapy vectors can bedelivered to a subject by, for example, intravenous injection, localadministration (see U.S. Pat. No. 5,328,470) or by stereotacticinjection (see e.g., Chen et al. (1994) Proc. Natl. Acad. Sci. USA91:3054 3057). The pharmaceutical preparation of the gene therapy vectorcan include the gene therapy vector in an acceptable diluent, or cancomprise a slow release matrix in which the gene delivery vehicle isimbedded. Alternatively, where the complete gene delivery vector can beproduced intact from recombinant cells, e.g., retroviral vectors, thepharmaceutical preparation can include one or more cells which producethe gene delivery system.

IX. Kits

The present invention also encompasses kits for detecting and/ormodulating biomarkers described herein. A kit of the present inventionmay also include instructional materials disclosing or describing theuse of the kit or an antibody of the disclosed invention in a method ofthe disclosed invention as provided herein. A kit may also includeadditional components to facilitate the particular application for whichthe kit is designed. For example, a kit may additionally contain meansof detecting the label (e.g., enzyme substrates for enzymatic labels,filter sets to detect fluorescent labels, appropriate secondary labelssuch as a sheep anti-mouse-HRP, etc.) and reagents necessary forcontrols (e.g., control biological samples or standards). A kit mayadditionally include buffers and other reagents recognized for use in amethod of the disclosed invention. Non-limiting examples include agentsto reduce non-specific binding, such as a carrier protein or adetergent.

EXAMPLES Example 1: Materials and Methods for Example 2

a. Clinical Cohort

Patients were prospectively enrolled on an IRB approved protocol(#1305013903) with written informed consent. Patients were eligible forthis study if they had metastatic prostate cancer with at least onemetastatic tumor biopsy and matched plasma sample (EDTA or StreckCell-Free DNA BCT®) and at least 2-50 ng of total cell free DNA (cfDNA)present in 1 mL of plasma. Whole exome sequencing (WES) of metastaticbiopsy was previously reported for 53/63 patients (Beltran et al. (2016)Nat Med 22:298-305; Beltran et al. (2018) Clin Cancer Res 25:43-51).Peripheral blood samples were approximately collected within 30 days oftreatment initiation (in ˜85% of cases). The choice of systemictherapies before plasma sample collection was at the discretion of thetreating physician. Treatments were administered continuously untilevidence of progression disease, unacceptable toxicity, or for a plannednumber of cycles in the case of chemotherapy according toregime-specific treatment protocols. Patients treated with at least onemonth duration on treatment were included, defined as “the duration oftime from initiation to discontinuation of therapy”. Clinical data wasobtained from the electronic medical record. Pathology review wasperformed and reported as adenocarcinoma or CRPC-NE using publishedmorphologic criteria (Epstein et al. (2014) Am J Surg Pathol38:756-767).

b. Plasma Processing and DNA Extraction and Quantification

Whole blood was centrifuged at 1,600 g×10 minutes at 4° C. within 3hours after blood collection. The plasma layer was transferred to 2 mlmicrocentrifuge tubes and centrifuged at 16,000 g×10 minutes at 4° C. toensure removal of any cellular debris. The plasma was then collected andstored at −80° C. cfDNA was extracted from plasma using the NeoGeneStarCell-Free DNA Purification kit per manufacturer's instructions(Somerset, N.J.). Briefly, for 2 ml plasma samples, cfDNA was isolatedvia proteolytic digestion with 1 μg of RNA carrier at 55° C. for 30minutes. cfDNA capture on the superparamagnetic particles wasaccomplished via addition of 3 volumes (6 mL) of LYS buffer, 0.8 mLisopropanol and 30 μL NGS™ Beads, capture of cfDNA via 30 minute roomtemperature incubation, 2× wash and 2×80% EtOH, air dry, and elution in30 μL 10 mM Tris, 0.1 mM EDTA (pH 8.5). Germline DNA was extracted fromextracellular blood components (PBMC) using the Promega Maxwell 16 MDxkit per manufacturer's instructions. Blood aliquots are vortexed brieflyand mixed with LYS buffer and proteinase K solution, vortexed brieflyagain, and incubated at 56° C. for 20 minutes. Lysates are thentransferred to the first well of a multiwall cartridge prefilled withreagents, 65 μl of elution buffer is loaded, and the automated systemsuccessfully isolates high concentration genomic DNA. cfDNA wasquantified with Qubit and quality also assessed by using Agilent's HighSensitivity DNA kit.

c. Whole exome sequencing of ctDNA and matched PBMC DNA

Based on the expected circulating DNA fragment size distribution and therange of input DNA identified from each plasma sample, the Roche SeqCapEZ Library SR (Pleasanton, Calif.) was opted for library preparation.Germline genomic DNA was sheared using the Covaris E220 Evolutioninstrument (Covaris, Woburn, Mass.). For cfDNA, input for library prepranged from 2.8-50 ng and for germline DNA input ranged from 50-100 ng.The libraries of both germline DNA and cfDNA were prepared using theKAPA HTP Library Preparation Protocol (Kapa Biosystems, Wilmington,Mass.) containing end repair, A-base addition, ligation of sequenceadaptors. The sample libraries were normalized and pooled following PCRamplification. Then the pooled libraries were hybridized with wholeexome SeqCap EZ probe pool. Finally, the pooled, indexed and amplifiedcapture sample libraries were sequenced using the Illumina HiSeq4000sequencer at 100 cycles (San Diego, Calif.). All plasma and matchednormal samples were run with single end protocol unless differentlyspecified. Illumina bcl2fastq2 Conversion Software was used todemultiplex samples into individual sample and converted per-cycle BCLbase call files into FASTQ files for downstream data analysis. WESsample processing and data generation procedure of tissue biopsiessequenced in this study follows the same protocol as in Beltran et al.(2016) Nat Med 22:298-305; all tissues were run with paired endprotocol.

d. Titration Experiment to Determine Optimal ctDNA Input for WES

Prior to profiling the whole cfDNA study cohort, the effect of inputamount for cfDNA on the sequencing based genomic profiles was studied.One patient with known genotype features (WCM163) was selected for thisexperiment. Specifically, the cfDNA was diluted into five concentrationsusing 5 ng, 10 ng, 20 ng, 50 ng, and 100 ng. For matched germline DNA,100 ng was used for all comparisons. All downstream library preparationand sequencing were conducted as stated above. Somatic copy number callsof 1000 cancer associated genes were compared (FIGS. 15A-15B).

e. WES Processing Pipeline

(i) Data Pre-Processing

Tumor tissues BAM files were generated through the WCM EnglanderInstitute of Precision Medicine pipeline (Beltran et al. (2015) JAMAOncol 1:466-474) and pre-processed at the University of Trento. As perthe cfDNA samples and matched germline DNA samples, the FastQC tool(available on the World Wide Web atbioinformatics.babraham.ac.uk/projects/fastqc) was run on the raw readsto assess their quality; quality metrics include average base quality,sequence duplication rate, and the k-mer enrichment along the length ofthe reads. These measures were utilized to assess whether the sequencingand the de-multiplexing of the samples was performed correctly. Afterinitial quality control, adapter sequences were trimmed usingTrimmomatic (Bolger, Lohse, and Usadel (2014) Bioinformatics30:2114-2120). Short reads were then aligned to GRC37/hg19 referenceusing BWA (Li and Durbin (2009) Bioinformatics 25:1754-1760). Picard(available on the World Wide Web at broadinstitute.github.io/picard/)and SAMtools (Li et al. (2009) Bioinformatics 25:2078-2079) were used togenerate single sorted BAM files for each patient's sample. BAM fileswere then realigned (to correct for possible misalignments due toindels) and recalibrated (to adjust for over- and under-estimated basequality scores in the data) using GATK standard pipelines (McKenna etal. (2010) Genome Res 20:1297-1303). Finally, SAMtools were used toadjust BAM MD tags (strings for mismatch positions). The alignmentquality of the BAM files was obtained by several metrics related to theaverage coverage and capture rate to calculate how many aligned readsfall within a capture region of the Nimblegen SeqCap EZ Exome V3 kit.For any given sample, the capture rate was given by the percent ofmapped reads that overlap any capture region in the kit and the totalnumber of mapped reads. Average coverage was computed from the capturedregions of the Nimblegen kit. Metrics from 62 processed patients' datashowed that average coverage for plasma DNA and germline DNA was 361×and 109×, respectively; average capture rates were 81% for plasma DNAand 77% for germline DNA (Table 2). All subsequent steps were applied toall samples, tissues and cfDNA, unless differently specified.

TABLE 2 Sequencing statistics of plasma genomics Mean coverage Mean incoverage Reads Fraction captured in Tot reads captured captured regionsReads Fraction captured Duplication after after after after Sample TypeTot reads captured captured regions fraction dedup dedup dedup dedupWCM0 Plasma 311122716 249173112 0.806 309 0.702 92846793 66369357 0.7281 WCM0 Germline 132057629 108314704 0.825 136 0.745 33704485 262421190.784 33 WCM1 Plasma 364378360 305606474 0.844 383 0.784 7880750560032334 0.767 74 WCM1 Germline 134725406 97302274 0.727 118 0.52763666839 43211401 0.684 52 WCM10 Plasma 325258174 268987483 0.832 3360.812 61283551 46755700 0.768 57 WCM10 Germline 157894805 123979502 0.79153 0.706 46487109 35302916 0.764 43 WCM119 Plasma 339732023 2812061490.833 352 0.778 75507734 56785036 0.757 70 WCM119 Germline 10240829879851989 0.785 99 0.563 44754960 32843646 0.739 41 WCM12 Plasma146838947 114718671 0.786 145 0.52 70486563 49513622 0.708 62 WCM12Germline 113199598 84472341 0.751 105 0.382 69924342 49088484 0.707 61WCM121 Plasma 377493251 307550034 0.82 382 0.818 68598741 50869345 0.74662 WCM121 Germline 91940399 70836961 0.776 87 0.54 42289477 315568390.751 39 WCM124 Plasma 329458636 264249102 0.807 330 0.71 9564724467145200 0.707 82 WCM124 Germline 114529272 89451053 0.786 112 0.59746159057 33554082 0.732 42 WCM131 Plasma 332482667 272390697 0.824 3390.813 61995026 46344122 0.752 57 WCM131 Germline 92823348 71135220 0.77188 0.551 41644766 30802749 0.745 38 WCM1388 Plasma 257042780 1833954200.718 233 0.595 104156766 61612998 0.596 77 WCM139 Plasma 401126385329103870 0.825 409 0.829 68441314 51128859 0.752 62 WCM139 Germline102066172 76920197 0.759 95 0.535 47451349 34310233 0.728 42 WCM14Germline 88651447 71739448 0.814 114 0.43 50539645 39530404 0.787 64WCM14- Plasma 267237615 205486181 0.774 256 0.807 51714781 362734020.706 45 TP1 WCM14- Plasma 431618248 317265361 0.74 394 0.834 7147229747583092 0.671 59 TP2 WCM14- Plasma 444003297 340281994 0.771 434 0.83175162329 50598425 0.678 63 TP3 WCM14- Plasma 452414260 342456465 0.762432 0.828 77886332 52199758 0.675 65 TP4 WCM142 Plasma 368352710309316542 0.845 387 0.804 72190734 55448922 0.773 68 WCM142 Germline116039055 92768415 0.804 117 0.647 40928654 29763588 0.732 37 WCM15Plasma 364394194 302697312 0.836 379 0.812 68651241 52682021 0.772 65WCM15 Germline 94349727 71561324 0.764 89 0.576 39959042 29145825 0.73436 WCM154 Plasma 413870150 339821702 0.826 426 0.787 88038344 647650390.741 79 WCM154 Germline 101422976 77663634 0.771 96 0.538 4689602134449792 0.74 43 WCM155 Plasma 350918758 287405648 0.824 361 0.72496788634 70503776 0.733 87 WCM155 Germline 156304396 129585473 0.834 1630.738 40876059 32358950 0.797 40 WCM156 Plasma 333582149 266044119 0.802330 0.837 54380948 39813523 0.737 49 WCM156 Germline 116725152 948251840.817 119 0.758 28202556 21958892 0.784 27 WCM158 Plasma 380118488306725227 0.812 382 0.801 75743656 54083211 0.719 66 WCM158 Germline98417749 75346177 0.771 93 0.522 47078980 34654706 0.741 43 WCM160Plasma 361020626 302887592 0.844 380 0.799 72555902 55613548 0.772 68WCM160 Germline 115411842 86946093 0.758 107 0.557 51123404 361382230.712 44 WCM161 Plasma 320462223 256166282 0.804 318 0.709 9322595265727627 0.71 80 WCM161 Germline 136355589 103139550 0.761 127 0.56359644595 42402294 0.716 52 WCM162 Plasma 317326927 260507673 0.826 3280.707 93038914 68037407 0.736 84 WCM162 Germline 129958304 1015063440.786 125 0.73 35055959 26512045 0.761 33 WCM163 Plasma 388446272335685040 0.869 427 0.8 77693118 62747957 0.813 78 WCM163 Germline282466085 241607179 0.86 305 0.787 60099767 48163405 0.806 60 WCM164Plasma 346434795 276372383 0.803 341 0.822 61770539 45482792 0.741 55WCM164 Germline 139483439 107088863 0.773 132 0.787 29726880 220573200.747 27 WCM169 Plasma 341180505 271379544 0.8 336 0.77 7864453956166872 0.719 68 WCM169 Germline 152231431 122050275 0.807 152 0.76835277083 26946654 0.769 33 WCM170 Plasma 437197105 350617744 0.807 4360.843 68819728 50567796 0.74 62 WCM170 Germline 127504894 97860652 0.772120 0.814 23728212 17464856 0.741 22 WCM172 Plasma 359396289 2884918310.808 357 0.767 83771387 60094618 0.722 73 WCM172 Germline 7336782354074003 0.742 67 0.514 35669665 25363022 0.716 31 WCM176 Plasma352608174 284271899 0.811 354 0.874 44272363 28694330 0.653 34 WCM176Germline 111450347 90401974 0.816 112 0.67 36805491 28884062 0.79 36WCM183 Plasma 379752487 308316924 0.817 384 0.741 98393037 70348682 0.7286 WCM183 Germline 128306159 101267651 0.794 127 0.61 50020410 368231920.741 46 WCM185 Plasma 525551626 423112703 0.81 527 0.817 9603349469124082 0.725 84 WCM185 Germline 99013894 77896867 0.792 96 0.7722785954 16993419 0.751 21 WCM185- Plasma 336871889 261840260 0.782 3280.84 53770438 37818640 0.708 47 TP1 WCM185- Plasma 363124324 2771264340.768 347 0.838 58886645 40516476 0.693 50 TP2 WCM185- Plasma 378894036279387694 0.742 348 0.844 59028730 38738043 0.661 48 TP3 WCM185- Plasma407324089 313511254 0.775 394 0.84 65168852 44818774 0.693 56 TP4 WCM192Plasma 384414155 308313856 0.807 385 0.812 72193475 53011960 0.739 65WCM192 Germline 136760982 99438480 0.732 120 0.76 32879233 231389100.709 28 WCM195 Plasma 357646622 297394829 0.836 375 0.777 7961954160251400 0.762 75 WCM195 Germline 82551231 59966483 0.731 74 0.44545830606 31567261 0.694 39 WCM198 Plasma 330615193 275542221 0.838 3500.783 71758779 54351419 0.762 68 WCM198 Germline 145254551 1026931300.712 125 0.457 78928376 52206844 0.666 63 WCM199 Plasma 349870338279756758 0.805 348 0.787 74377712 53383885 0.723 65 WCM199 Germline73165515 53604497 0.738 67 0.393 44409836 31166112 0.707 38 WCM2 Plasma382980081 315077922 0.828 393 0.806 74148650 56102263 0.762 69 WCM2Germline 91146404 65561628 0.724 80 0.598 36626465 25446296 0.7 31WCM201 Plasma 402714823 307603800 0.769 379 0.827 69714756 466230620.674 57 WCM201 Germline 78864621 61573953 0.786 77 0.375 4928369337016542 0.756 46 WCM207 Plasma 325803297 276547327 0.854 350 0.78171367562 55651835 0.785 69 WCM207 Germline 119213126 90358149 0.763 1120.59 48938220 34467698 0.709 42 WCM212 Plasma 391379376 319619872 0.822404 0.793 80878112 59630513 0.742 74 WCM212 Germline 69578577 517164740.748 65 0.391 42365654 30168754 0.717 38 WCM213 Plasma 341951707286459655 0.843 358 0.792 71297743 54244071 0.766 66 WCM213 Germline85531748 63262393 0.745 78 0.521 40953823 28185040 0.693 35 WCM216Plasma 399678023 320815070 0.808 398 0.788 84739921 58463964 0.695 72WCM216 Germline 134810654 87561520 0.655 107 0.352 87354881 51952767 0.663 WCM218 Plasma 270804563 226725381 0.842 284 0.768 62896545 481067420.77 59 WCM218 Germline 95995138 71825506 0.753 89 0.528 4536230931755524 0.705 39 WCM219 Plasma 295904118 232966360 0.792 288 0.81455004409 38729540 0.709 48 WCM219 Germline 98077887 76062103 0.78 950.427 56187677 41708133 0.747 52 WCM223 Plasma 401926996 313797098 0.786389 0.802 79608094 54703327 0.692 67 WCM223 Germline 89279610 689611990.777 86 0.413 52433347 38706969 0.743 48 WCM243 Plasma 332907337262511887 0.794 323 0.737 87453344 60845148 0.701 74 WCM243 Germline109125850 82253426 0.759 101 0.841 17326455 12101985 0.703 15 WCM247Plasma 369235160 294445463 0.802 368 0.76 88618869 61551654 0.7 75WCM247 Germline 175875262 138562855 0.793 173 0.814 32753419 224826440.691 27 WCM252 Plasma 397034260 336504861 0.852 426 0.781 8695108267064520 0.776 83 WCM252 Germline 111621700 85526634 0.771 107 0.57647379534 33894485 0.72 42 WCM253 Plasma 349335311 276009548 0.795 3420.787 74422557 51128968 0.692 62 WCM253 Germline 172203151 1353439200.791 169 0.788 36498615 25505416 0.704 31 WCM261 Plasma 456866372367388703 0.809 455 0.798 92430033 63948233 0.697 78 WCM261 Germline68958271 48396275 0.707 61 0.323 46667403 31010467 0.67 39 WCM341 Plasma412880192 329820557 0.804 409 0.767 96245678 67457090 0.706 83 WCM341Germline 87596583 59815812 0.688 74 0.337 58062736 37359850 0.648 46WCM365 Plasma 431976173 340308459 0.793 426 0.794 89131325 615190890.695 76 WCM365 Germline 95101752 72668341 0.769 91 0.401 5699497541359034 0.731 51 WCM366 Plasma 305675512 235722635 0.776 293 0.79861642577 42605631 0.696 52 WCM366 Germline 94904757 71028303 0.753 880.391 57802427 41093684 0.716 51 WCM369 Plasma 392206305 307159082 0.788384 0.798 79419300 54862421 0.696 67 WCM369 Germline 81574616 616024460.76 77 0.367 51655125 37287336 0.727 46 WCM4 Plasma 349741918 2874940500.827 358 0.812 65574106 49221059 0.756 60 WCM4 Germline 136167012105295507 0.778 129 0.715 38859819 29132187 0.755 36 WCM6 Plasma317200728 262681116 0.833 328 0.789 66791492 51019927 0.769 63 WCM6Germline 115587780 95627214 0.832 120 0.823 20402683 15258372 0.753 19WCM63 Plasma 264592541 218381370 0.83 271 0.832 44383911 33611154 0.76241 WCM63 Germline 87498006 61719919 0.71 76 0.585 36346776 248271710.688 30 WCM677 Plasma 335742996 270110809 0.81 339 0.82 6059073343838656 0.728 54 WCM677 Germline 93862570 70646764 0.758 88 0.39356965506 40769042 0.721 50 WCM7 Plasma 316062922 257857266 0.821 3240.705 93212502 67504147 0.729 83 WCM7 Germline 97224429 74569077 0.77293 0.598 39095858 27751560 0.715 34 WCM73 Plasma 294754578 2275942160.777 280 0.842 46554227 32695790 0.707 40 WCM73 Germline 11923602589389895 0.755 109 0.735 31581338 22906218 0.73 28 WCM78 Plasma460196208 383499927 0.838 480 0.829 78503572 59915855 0.768 74 WCM78Germline 100073107 78633474 0.791 98 0.578 42281085 31987986 0.762 40WCM80 Plasma 352697630 272591824 0.778 335 0.845 54657927 38416578 0.70847 WCM80 Germline 134656931 104496575 0.781 129 0.698 40596881 305245760.757 38 WCM89 Plasma 391524851 321014747 0.825 400 0.827 6763293450118395 0.746 61 WCM89 Germline 87618661 70667991 0.812 88 0.52841356826 32360127 0.788 40 WCM9 Plasma 300828453 249127616 0.833 3100.789 63403107 48376079 0.768 59 WCM9 Germline 153725403 122679104 0.803151 0.694 46989357 36197890 0.775 44 WCM90 Plasma 288566429 2366906700.825 297 0.69 89560896 65987775 0.742 81 WCM90 Germline 9994829876273435 0.768 95 0.539 46115597 33829674 0.739 42 WCM91 Plasma353999832 272524812 0.775 334 0.833 59005760 41727140 0.712 50 WCM91Germline 129574648 97500264 0.758 119 0.847 19797087 13992622 0.712 17

(ii) Sample's Identity Check

In order to verify the correct match of all individual's samples, asolid genotype distance based test was applied, SPIA (Demichelis et al.(2008) Nucleic Acids Res 36:2446-2456) exploiting the related R packageSPIAssay. Genotypes of 334 selected SNPs were computed using ASEQ(Romanel et al. (2015) BMC Med Genomics 8:9). The 334 SNPs werepreviously selected based on the minor allele frequency (MAF) anduniform distribution across the genome.

(iii) Optimized De-Duplication Procedure for WES Plasma Data from SingleEnd

Protocol and with Deep Coverage WES data generated from both germlineand cfDNA study samples showed high fractions of read duplicates in thesample cohort (mean 59% and 79%, respectively). Anti-correlation betweenduplication percentage and input DNA was observed (−0.83 Pearsoncoefficient, P=9e−04). Duplication levels in off-target regions werecomparable to on-target region. Provided that without using specifictechnologies (e.g. molecular barcoding) it is not possible to measureand quantify the exact proportions of PCR and natural duplication (dueto high-coverage), an ad-hoc computational solution that limits theimpact of non-natural reads duplicates in down-stream copy numberanalyses was opted for. First, the empirical distribution of readsduplicates at different coverage intervals from all samples of thecohort was measured. Then each coverage interval the 50th, 75th and 90thpercentiles were collected and these percentiles were used across allcoverage intervals to create three different duplication thresholds(FIG. 15C). Finally, these thresholds were applied when the coveragestatistics at single base resolution is computed for down-streamanalysis. Specifically, when coverage statistics are computed for aposition x in the genome, the raw coverage C is first computedconsidering all reads and is then normalized considering the duplicationthreshold T specific for C. Coverage statistics were computed for allthree 50th, 75th and 90th percentiles thresholds. Coverage distributionsobtained applying the different duplication thresholds are shown in(FIG. 15D).

(iv) WES Segmentation

Segmentation of patient's samples was performed using the recent toolFACETS (Shen and Seshan (2016) Nucleic Acids Res 44:e131), acomputational method that extends the standard circular binarysegmentation (CBS) algorithm to a joint segmentation that combines readcounts and SNPs allelic fraction data. To deal with plasma samples, thepre-processing module of FACETS was extended including thede-duplication procedure and segmentation was performed consideringseparately all three 50th, 75th and 90th percentiles thresholds andcomplete de-deduplication. Comparison of segmentation results on a largecancer gene list (N=920) showed that although segmentation signal fromde-duplicated samples strongly correlates with raw segmentation signal(were no de-duplication was applied) in all cases (FIG. 15E), thestronger the de-duplication level applied the higher the divergence ofthe signal from the diagonal, indicating a loss of detection power.Based on this observation 75^(th) percentile thresholds was used forcfDNA samples WES segmentation and related somatic copy numberdownstream analyses (Table 3). Study cohort WES segmented data wereadjusted for tumor ploidy and tumor content revealing an overall plasmasignal similar to tissue-based data (FIG. 1B), with peaks distinctive ofmono- and bi-allelic deletions and of gains of one, two, three or moregene copies.

TABLE 3 Somatic Copy Number Aberration Data Chr Start End log2 CorrectedcnA cnB Sample (hg19) (hg19) (hg19) (ratio) log2(ratio) cnA cnB integerinteger WCM0 1 14930 11854012 0.0028 −0.1596 0.8953 0.8953 1 1 WCM0 111854476 19581312 −0.2629 −0.7783 1.0601 0.106 1 0 WCM0 1 1958245229823400 −0.0538 −0.2795 0.8239 0.8239 1 1 WCM0 1 30117383 312144820.261 0.3323 NA NA NA NA WCM0 1 31215256 50310863 0.5154 0.7546 1.68711.6871 2 2 WCM0 1 50310946 91182214 0.2759 0.3584 1.282 1.282 1 1 WCM0 191182531 121116688 −0.317 −0.9262 1.0467 0.0058 1 0 WCM0 1 142653721248844954 −0.0199 −0.2071 0.8663 0.8663 1 1 WCM0 1 248845365 249213967−0.2354 −0.7065 NA NA NA NA WCM0 10 225982 135477913 −0.3097 −0.90571.0509 0.0166 1 0 WCM0 11 193096 433992 −0.1582 −0.516 1.1376 0.261 1 0WCM0 11 434110 69482659 −0.333 −0.9719 1.0275 −0.0078 1 0 WCM0 1169486539 116906728 0.1341 0.1005 1.0721 1.0721 1 1 WCM0 11 116967847119005075 −0.2071 −0.635 0.6504 0.6375 1 1 WCM0 11 119005627 1346059060.1505 0.1315 1.0954 1.0954 1 1 WCM0 12 148637 25679764 −0.3255 −0.95040.9491 0.0858 1 0 WCM0 12 25699397 40963653 0.1749 0.1769 1.1305 1.13051 1 WCM0 12 40964265 133810703 −0.3357 −0.9798 1.0237 −0.0096 1 0 WCM013 19042005 78335167 −0.285 −0.8375 1.1206 −0.0014 1 0 WCM0 13 78337334115028400 0.2542 0.3202 2.5145 −0.0174 3 0 WCM0 13 115030714 115089411−0.0081 −0.1823 NA NA NA NA WCM0 14 19110263 107283269 0.015 −0.13440.9111 0.9111 1 1 WCM0 15 20083897 102506284 0.0657 −0.0322 0.97790.9779 1 1 WCM0 16 67600 90168697 −0.322 −0.9403 1.1154 −0.0731 1 0 WCM017 131595 7592928 0.1833 0.1923 1.1426 1.1426 1 1 WCM0 17 76040428094020 −0.2775 −0.8172 0.7265 0.4086 1 0 WCM0 17 8094200 287729300.0965 0.0283 1.0198 1.0198 1 1 WCM0 17 28776653 59760697 −0.328 −0.95761.0713 −0.0414 1 0 WCM0 17 59760996 81187901 0.1457 0.1223 1.0885 1.08851 1 WCM0 18 47689 15322279 0.406 0.5789 1.4937 1.4937 1 1 WCM0 1815323346 78005214 −0.3025 −0.8856 1.058 0.0246 1 0 WCM0 19 1050107807937 0.1688 0.1656 1.1216 1.1216 1 1 WCM0 19 7808088 9921565 0.80841.1912 3.1723 1.3945 3 1 WCM0 19 9921880 10506754 0.3014 0.4028 1.32211.3221 1 1 WCM0 19 10506911 12902785 0.7952 1.1723 2.8098 1.6976 3 2WCM0 19 12903623 17213331 0.3231 0.4401 1.4795 1.2339 1 1 WCM0 1917256318 19932367 0.8172 1.2037 3.5045 1.1021 4 1 WCM0 19 1993831037006142 0.2043 0.2307 1.1734 1.1734 1 1 WCM0 19 37006525 387084590.6666 0.9852 2.6912 1.268 3 1 WCM0 19 38709205 42731594 0.2423 0.29921.2305 1.2305 1 1 WCM0 19 42734945 42852555 −1.203 NA NA NA NA NA WCM019 42853770 43883320 0.5546 0.8156 3.485 0.035 3 0 WCM0 19 4391062344174086 −0.6559 −2.2179 0.4019 0.028 0 0 WCM0 19 44222890 443355540.2177 0.2551 NA NA NA NA WCM0 19 44339735 46305466 0.6859 1.0139 2.20411.8345 2 2 WCM0 19 46307593 50931526 0.1288 0.0904 1.0646 1.0646 1 1WCM0 19 50936235 52934785 0.6369 0.9409 2.104 1.7353 2 2 WCM0 1952937271 59093696 0.2368 0.2893 1.222 1.222 1 1 WCM0 2 41662 69870406−0.0445 −0.2595 0.8354 0.8354 1 1 WCM0 2 69871128 88411605 −0.3345−0.9762 1.049 −0.0323 1 0 WCM0 2 88422614 89035298 −0.3 −0.8788 NA NA NANA WCM0 2 89036230 113289032 0.038 −0.0875 0.9412 0.9412 1 1 WCM0 2113300115 149449371 −0.2819 −0.8291 1.0002 0.1256 1 0 WCM0 2 149501317228135631 0.1574 0.1443 1.1052 1.1052 1 1 WCM0 2 228135709 230253000−0.0446 −0.2598 0.8352 0.8352 1 1 WCM0 2 230271992 234368816 −0.2861−0.8405 0.9839 0.1331 1 0 WCM0 2 234368850 243037091 0.0815 −0.0010.9993 0.9993 1 1 WCM0 20 68396 62934572 0.0544 −0.0545 0.9629 0.9629 11 WCM0 21 9590305 48084175 0.1104 0.0551 1.0389 1.0389 1 1 WCM0 2216159060 51219089 −0.3237 −0.9453 1.0299 0.0087 1 0 WCM0 3 23947273657753 −0.3311 −0.9665 1.036 −0.0125 1 0 WCM0 3 73673872 942261020.1212 0.076 1.0541 1.0541 1 1 WCM0 3 94226357 122143416 −0.2615 −0.77461.1177 0.0514 1 0 WCM0 3 122143751 197896656 0.1542 0.1384 1.1007 1.10071 1 WCM0 4 53397 61529776 −0.0769 −0.33 0.7955 0.7955 1 1 WCM0 462066964 175429233 0.1502 0.1308 1.0949 1.0949 1 1 WCM0 4 175429954190878508 −0.025 −0.2178 0.8599 0.8599 1 1 WCM0 5 90714 123972927 0.0519−0.0595 0.9596 0.9596 1 1 WCM0 5 123973546 136953689 −0.3301 −0.96371.0388 −0.0133 1 0 WCM0 5 136953959 180687824 0.1227 0.0787 1.056 1.0561 1 WCM0 6 203546 126202321 0.1298 0.0923 1.0661 1.0661 1 1 WCM0 6126203596 166743676 −0.0652 −0.3044 0.8098 0.8098 1 1 WCM0 6 166744943170892921 0.1034 0.0417 1.0294 1.0294 1 1 WCM0 7 193245 29519994 0.13310.0985 1.0707 1.0707 1 1 WCM0 7 29523654 38269668 −0.3354 −0.9787 0.97730.0376 1 0 WCM0 7 38269935 158937074 0.1203 0.0742 1.0527 1.0527 1 1WCM0 8 163457 2092866 −1.0648 NA −0.0753 −0.0753 0 0 WCM0 8 279534036703319 −0.1837 −0.5773 1.2818 0.0586 1 0 WCM0 8 36704395 1055441130.2049 0.2319 1.1744 1.1744 1 1 WCM0 8 105601136 146279398 −0.201−0.6198 1.268 0.0335 1 0 WCM0 9 14876 3469140 −0.6076 −1.9718 0.31940.1905 0 0 WCM0 9 3824162 19032837 −0.0113 −0.189 0.8772 0.8772 1 1 WCM09 19049691 37735766 −0.2567 −0.7619 1.1867 −0.0072 1 0 WCM0 9 3773713897321156 −0.0346 −0.2383 0.8478 0.8478 1 1 WCM0 9 97321430 1411075250.1381 0.1079 1.0777 1.0777 1 1 WCM0 X 2700082 123026595 0.0914 0.0183NA NA NA NA WCM0 X 123034363 154493590 0.361 0.5041 NA NA NA NA WCM0_LM11 809022 2560735 −0.2824 −0.5322 0.917 0.466 1 0 WCM0_LM1 1 29383186215836 −0.1019 −0.3389 1.031 0.5503 1 1 WCM0_LM1 1 6219610 11986007−0.3283 −0.5817 0.883 0.4534 1 0 WCM0_LM1 1 11994910 19609254 −0.8045−1.103 0.9417 −0.0107 1 0 WCM0_LM1 1 19611241 26441091 −0.2779 −0.52730.9148 0.4729 1 0 WCM0_LM1 1 26448447 29391691 −0.4169 −0.6775 0.83270.4178 1 0 WCM0_LM1 1 29424270 29652174 −0.1691 −0.4107 NA NA NA NAWCM0_LM1 1 31186472 31899691 0.7196 0.5237 NA NA NA NA WCM0_LM1 131901898 32265645 0.941 0.7526 NA NA NA NA WCM0_LM1 1 32266186 336133230.668 0.4702 1.9677 0.803 2 1 WCM0_LM1 1 33623891 35370589 1.1411 0.9585NA NA NA NA WCM0_LM1 1 35370948 41300682 0.7621 0.5677 2.0562 0.9082 2 1WCM0_LM1 1 41303372 44778928 0.9534 0.7654 2.3307 1.0689 2 1 WCM0_LM1 144785393 50886915 0.8126 0.62 2.1425 0.9313 2 1 WCM0_LM1 1 5090709855203321 0.3774 0.1673 1.3052 0.9408 1 1 WCM0_LM1 1 55207079 619209660.6683 0.4705 1.6157 1.1555 2 1 WCM0_LM1 1 62149156 64011693 0.3460.1344 1.3035 0.8917 1 1 WCM0_LM1 1 64017391 91182777 0.5953 0.39471.502 1.1274 2 1 WCM0_LM1 1 91382484 92200462 −0.6736 −0.9581 NA NA NANA WCM0_LM1 1 92224347 94012976 −0.8216 −1.122 0.9474 −0.0286 1 0WCM0_LM1 1 94014931 109154756 −0.5479 −0.8201 1.1279 0.0049 1 0 WCM0_LM11 109158979 109968887 −0.792 −1.0891 0.9572 −0.0171 1 0 WCM0_LM1 1110009487 112525389 −0.5036 −0.7717 1.1653 0.0061 1 0 WCM0_LM1 1112958891 115469166 −0.7305 −1.0209 0.9957 −0.0101 1 0 WCM0_LM1 1115487092 120166453 −0.4917 −0.7588 1.1831 −0.0011 1 0 WCM0_LM1 1120166737 120612013 −0.3588 −0.6146 NA NA NA NA WCM0_LM1 1 120612265149943111 −0.0077 −0.2386 1.0096 0.6855 1 1 WCM0_LM1 1 149949406151824941 −0.2546 −0.5023 0.8038 0.6081 1 1 WCM0_LM1 1 151825991153517315 0.0987 −0.1258 1.2528 0.5802 1 1 WCM0_LM1 1 153520298156846393 −0.3847 −0.6427 0.8457 0.4354 1 0 WCM0_LM1 1 156848995160846646 −0.0056 −0.2364 1.1004 0.5973 1 1 WCM0_LM1 1 160849077161487946 −0.3753 −0.6324 NA NA NA NA WCM0_LM1 1 161494809 180461504−0.0819 −0.3175 1.0393 0.5656 1 1 WCM0_LM1 1 180464581 198828261 0.2065−0.0121 0.9979 0.9854 1 1 WCM0_LM1 1 199997031 205739877 0.0392 −0.18890.9591 0.7954 1 1 WCM0_LM1 1 205740573 211433487 0.2414 0.0247 1.07180.9627 1 1 WCM0_LM1 1 211444578 213414090 −0.0266 −0.2587 0.8589 0.81271 1 WCM0_LM1 1 213414438 223957621 0.1938 −0.0255 0.997 0.968 1 1WCM0_LM1 1 223958181 226568728 −0.0687 −0.3034 0.844 0.7767 1 1 WCM0_LM11 226570771 233231579 0.1508 −0.0708 1.0335 0.8707 1 1 WCM0_LM1 1233270873 233394468 −0.5374 −0.8086 NA NA NA NA WCM0_LM1 1 233394739234745259 0.1789 −0.0412 1.0886 0.855 1 1 WCM0_LM1 1 235277252 236766527−0.1217 −0.36 0.8241 0.7343 1 1 WCM0_LM1 1 236767326 246493813 0.1125−0.1113 1.0226 0.8289 1 1 WCM0_LM1 1 246498713 247582128 −0.0918 −0.3281NA NA NA NA WCM0_LM1 1 247582351 249212569 0.2842 0.0696 1.1905 0.9084 11 WCM0_LM1 10 226016 5435752 −0.5291 −0.7996 1.1446 0.0044 1 0 WCM0_LM110 5436261 44873331 −0.7452 −1.0371 0.9786 −0.004 1 0 WCM0_LM1 1044873732 69106478 −0.52 −0.7896 1.1528 0.0042 1 0 WCM0_LM1 10 6928164771139853 −1.028 −1.3541 0.8048 −0.0225 1 0 WCM0_LM1 10 71142230 73857254−0.6241 −0.9036 1.0607 0.0084 1 0 WCM0_LM1 10 73887823 76982173 −0.8501−1.1539 0.9108 −0.012 1 0 WCM0_LM1 10 76989390 93582099 −0.5882 −0.86421.0971 0.0015 1 0 WCM0_LM1 10 93586976 99511158 −0.7617 −1.0555 0.9669−0.0046 1 0 WCM0_LM1 10 99512581 101162498 −0.5082 −0.7768 1.1735−0.0062 1 0 WCM0_LM1 10 101163194 105206915 −0.8467 −1.1501 0.9115−0.0104 1 0 WCM0_LM1 10 105207126 120460820 −0.6083 −0.8862 1.0801 0.0021 0 WCM0_LM1 10 120467037 121680507 −0.8483 −1.1518 0.908 −0.0079 1 0WCM0_LM1 10 121685686 135373640 −0.5776 −0.8526 1.1056 0.0019 1 0WCM0_LM1 11 193096 1776250 −0.7824 −1.0785 0.9408 0.0063 1 0 WCM0_LM1 111776299 4389395 −0.6441 −0.9255 1.0697 −0.0167 1 0 WCM0_LM1 11 44067278123157 −0.4237 −0.6848 1.2361 0.0081 1 0 WCM0_LM1 11 8132292 8959697−0.5917 −0.868 1.1034 −0.0076 1 0 WCM0_LM1 11 8970045 10064480 −0.8553−1.1597 0.9078 −0.0126 1 0 WCM0_LM1 11 10215446 16824514 −0.4859 −0.75251.1823 0.0049 1 0 WCM0_LM1 11 16824776 18787411 −0.6992 −0.9863 1.0215−0.0119 1 0 WCM0_LM1 11 18793550 32622213 −0.4574 −0.7215 1.2076 0.00541 0 WCM0_LM1 11 32623301 33375034 −0.8244 −1.1252 NA NA NA NA WCM0_LM111 33564085 45970423 −0.5422 −0.8139 1.1251 0.0126 1 0 WCM0_LM1 1145970983 48185007 −0.8971 −1.2064 0.8814 −0.0147 1 0 WCM0_LM1 1148186104 61026319 −0.5808 −0.8561 1.0903 0.0145 1 0 WCM0_LM1 11 6102649669488069 −0.8041 −1.1025 0.9374 −0.006 1 0 WCM0_LM1 11 69490017 782399500.2413 0.0245 1.0214 1.0128 1 1 WCM0_LM1 11 78270557 107224313 0.37480.1646 1.1267 1.115 1 1 WCM0_LM1 11 107260927 107462599 0.2867 0.0723 NANA NA NA WCM0_LM1 11 107463154 108351984 0.0341 −0.1943 0.8935 0.8546 11 WCM0_LM1 11 108352910 116824749 0.2824 0.0678 1.0877 1.0085 1 1WCM0_LM1 11 116827649 117150646 −0.835 −1.137 NA NA NA NA WCM0_LM1 11117150988 118656889 −0.164 −0.4052 0.9967 0.5136 1 1 WCM0_LM1 11118754661 119025220 −0.8446 −1.1477 NA NA NA NA WCM0_LM1 11 119025569134257523 0.3485 0.1371 1.1054 1.0939 1 1 WCM0_LM1 12 247582 6425588−0.6186 −0.8975 1.0726 0.001 1 0 WCM0_LM1 12 6426664 7069357 −0.8563−1.1608 0.9102 −0.0156 1 0 WCM0_LM1 12 7069584 9577125 −0.6833 −0.96871.0261 −0.0042 1 0 WCM0_LM1 12 9578130 9747907 0.2345 0.0174 NA NA NA NAWCM0_LM1 12 9750669 12874086 −0.631 −0.9112 1.0565 0.007 1 0 WCM0_LM1 1212917601 18242237 −0.263 −0.5114 1.3961 0.0069 1 0 WCM0_LM1 12 1843503522837810 −0.8009 −1.099 0.9261 0.0076 1 0 WCM0_LM1 12 23687369 24365375−0.1651 −0.4064 NA NA NA NA WCM0_LM1 12 24736749 25348029 −0.9242−1.2369 NA NA NA NA WCM0_LM1 12 25356961 28605426 0.1452 −0.0767 0.97620.9202 1 1 WCM0_LM1 12 28637090 31359073 0.5247 0.3212 1.4004 1.0984 1 1WCM0_LM1 12 31435823 33049598 0.1572 −0.0641 1.1039 0.8092 1 1 WCM0_LM112 33529782 40761617 0.5696 0.368 NA NA NA NA WCM0_LM1 12 4130222341903648 −0.1107 −0.3482 NA NA NA NA WCM0_LM1 12 41946539 49048731−0.2021 −0.446 1.4657 0.0024 1 0 WCM0_LM1 12 49050561 51901248 −0.5135−0.7825 1.1767 −0.014 1 0 WCM0_LM1 12 52056612 53228012 −0.19 −0.4331.4698 0.0116 1 0 WCM0_LM1 12 53233021 54070021 −0.5642 −0.8379 1.1446−0.0257 1 0 WCM0_LM1 12 54105893 56137502 −0.2827 −0.5326 NA NA NA NAWCM0_LM1 12 56142337 57109792 −0.5773 −0.8523 NA NA NA NA WCM0_LM1 1257109935 57976312 −0.3855 −0.6435 1.2886 −0.0083 1 0 WCM0_LM1 1257976887 69995124 −0.3322 −0.5859 1.3327 −2.00E−04  1 0 WCM0_LM1 1270003852 93169842 −0.1897 −0.4327 1.4709 0.0109 1 0 WCM0_LM1 12 93170629102455041 −0.4182 −0.6789 1.2525 −0.0032 1 0 WCM0_LM1 12 102455729108926064 −0.2438 −0.4907 1.4363 −0.0129 1 0 WCM0_LM1 12 108929226110207078 −0.4205 −0.6814 1.2544 −0.0073 1 0 WCM0_LM1 12 110221534112924336 −0.6313 −0.9115 NA NA NA NA WCM0_LM1 12 112926890 120546214−0.4116 −0.6718 1.2659 −0.0104 1 0 WCM0_LM1 12 120565808 124333351−0.6187 −0.8976 1.0908 −0.0173 1 0 WCM0_LM1 12 124335464 133779375−0.3783 −0.6357 1.2912 −0.0039 1 0 WCM0_LM1 13 19705463 23869639 −0.8361−1.1382 0.9253 −0.0166 1 0 WCM0_LM1 13 23894941 61989243 −0.6127 −0.8911.0778 6.00E−04 1 0 WCM0_LM1 13 63745813 72014784 −1.1874 −1.5364 NA NANA NA WCM0_LM1 13 72049242 80911823 −0.1039 −0.3411 1.5777 0.0013 2 0WCM0_LM1 13 84453543 115089411 0.6286 0.4292 2.6897 0.0033 3 0 WCM0_LM114 19553559 22237284 0.0739 −0.1521 0.9057 0.8942 1 1 WCM0_LM1 1422251213 23012177 0.3652 0.1546 1.1329 1.0933 1 1 WCM0_LM1 14 2301308123652157 −0.0473 −0.2808 0.8608 0.7855 1 1 WCM0_LM1 14 23745164 313487120.1963 −0.0229 0.9967 0.9718 1 1 WCM0_LM1 14 31349614 34419896 0.0188−0.2105 0.9119 0.8165 1 1 WCM0_LM1 14 34904506 35871262 −0.2295 −0.4754NA NA NA NA WCM0_LM1 14 35871728 50052772 0.1212 −0.1021 0.9445 0.9189 11 WCM0_LM1 14 50065793 51102099 −0.0642 −0.2987 NA NA NA NA WCM0_LM1 1451107548 73198645 0.1367 −0.0857 0.9473 0.9373 1 1 WCM0_LM1 14 7322002075904831 −0.0624 −0.2968 0.8574 0.7707 1 1 WCM0_LM1 14 75928152 939949540.0887 −0.1365 0.9213 0.8982 1 1 WCM0_LM1 14 93995602 95236210 0.29040.0761 1.0663 1.042 1 1 WCM0_LM1 14 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WCM0_LM1 15 91549254 102359167 0.2896 0.0752 1.1299 0.9772 11 WCM0_LM1 16 79642 3063747 −0.801 −1.0992 0.9394 −0.0059 1 0 WCM0_LM116 3064029 19711751 −0.8781 −1.1851 0.8879 −0.0083 1 0 WCM0_LM1 1619718309 20990708 −0.6633 −0.9467 1.0422 −0.0046 1 0 WCM0_LM1 1620994031 31202744 −0.9154 −1.2271 0.8681 −0.0138 1 0 WCM0_LM1 1631212936 54317607 −0.6781 −0.9631 1.0463 −0.0204 1 0 WCM0_LM1 1654318237 56435736 −0.3991 −0.6582 NA NA NA NA WCM0_LM1 16 5643705766638885 −0.7449 −1.0369 0.9826 −0.0078 1 0 WCM0_LM1 16 6664232670710859 −0.8779 −1.185 0.8919 −0.0122 1 0 WCM0_LM1 16 70711784 90162300−0.7306 −1.021 0.994 −0.0085 1 0 WCM0_LM1 17 131595 5392711 0.0242−0.2047 0.8787 0.8567 1 1 WCM0_LM1 17 5405186 7579619 0.1419 −0.08020.9529 0.9389 1 1 WCM0_LM1 17 7579885 7951724 −0.7752 −1.0705 NA NA NANA WCM0_LM1 17 7976291 8647931 −0.3035 −0.555 0.9065 0.4548 1 0 WCM0_LM117 8700863 28030079 0.1612 −0.0598 1.0231 0.8956 1 1 WCM0_LM1 1728120949 28773023 0.7014 0.5049 NA NA NA NA WCM0_LM1 17 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NA WCM0_LM1 19 1134891111408997 0.9161 0.727 NA NA NA NA WCM0_LM1 19 11409571 11598603 0.2027−0.0161 NA NA NA NA WCM0_LM1 19 11606831 12089920 1.4349 1.2596 NA NA NANA WCM0_LM1 19 12125850 12577572 0.2036 −0.0152 NA NA NA NA WCM0_LM1 1912595529 12886276 0.9556 0.7677 NA NA NA NA WCM0_LM1 19 1290268114703188 0.2622 0.0465 1.2107 0.8547 1 1 WCM0_LM1 19 14705319 152210741.0422 0.8568 2.7988 0.8233 3 1 WCM0_LM1 19 15221533 15795976 0.3920.1826 1.3605 0.9093 1 1 WCM0_LM1 19 15806710 15882828 0.5559 0.3537 NANA NA NA WCM0_LM1 19 15905002 16222893 1.0801 0.8958 2.8671 0.8543 3 1WCM0_LM1 19 16229016 16436803 0.2968 0.0828 NA NA NA NA WCM0_LM1 1916437752 16548596 1.005 0.8185 NA NA NA NA WCM0_LM1 19 16551617 172133410.2593 0.0434 1.2082 0.8529 1 1 WCM0_LM1 19 17256224 18085909 0.91420.725 2.5448 0.7609 3 1 WCM0_LM1 19 18092501 18538151 1.4431 1.26794.0126 0.8037 4 1 WCM0_LM1 19 18538742 18870864 1.0318 0.8462 2.76730.8281 3 1 WCM0_LM1 19 18876309 19011259 0.2326 0.0154 NA NA NA NAWCM0_LM1 19 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149501221 −0.6715 −0.9557 1.0372 −0.006 1 0 WCM0_LM1 2149511594 160836384 0.305 0.0914 1.0688 1.0621 1 1 WCM0_LM1 2 160840487170131630 0.441 0.2338 1.1808 1.171 1 1 WCM0_LM1 2 170134365 1768603000.2328 0.0156 1.0225 0.9991 1 1 WCM0_LM1 2 176944789 183387074 0.52960.3263 1.259 1.2486 1 1 WCM0_LM1 2 183582884 201677927 0.3293 0.11691.0844 1.0844 1 1 WCM0_LM1 2 201680121 204360039 0.0769 −0.1489 0.91050.8933 1 1 WCM0_LM1 2 204571465 219082192 0.3192 0.1064 1.0822 1.0709 11 WCM0_LM1 2 219090701 219689292 0.0778 −0.148 0.9101 0.8949 1 1WCM0_LM1 2 219691684 223918019 0.2703 0.055 1.0454 1.0323 1 1 WCM0_LM1 2224462182 230787220 −0.151 −0.3913 1.0371 0.4878 1 0 WCM0_LM1 2230840964 234344499 −0.7432 −1.035 0.98 −0.004 1 0 WCM0_LM1 2 234345138234656640 −0.0758 −0.311 1.0628 0.5493 1 1 WCM0_LM1 2 234669089234835260 0.0824 −0.1431 NA NA NA NA WCM0_LM1 2 234839404 2421781490.3442 0.1325 1.1031 1.0893 1 1 WCM0_LM1 2 242178251 242815433 0.1405−0.0817 0.9689 0.921 1 1 WCM0_LM1 20 68375 168591 0.0729 −0.1532 NA NANA NA WCM0_LM1 20 170225 871038 −0.2172 −0.4621 0.9782 0.4737 1 0WCM0_LM1 20 896641 2312944 0.0923 −0.1326 1.1978 0.6266 1 1 WCM0_LM1 202315739 6011924 −0.2125 −0.4571 0.9667 0.4902 1 0 WCM0_LM1 20 601276725271125 0.0304 −0.1982 1.1702 0.5731 1 1 WCM0_LM1 20 25273088 25657666−0.1229 −0.3613 NA NA NA NA WCM0_LM1 20 25666234 34317461 −0.2838−0.5337 0.9101 0.4715 1 0 WCM0_LM1 20 34320036 35731214 −0.0717 −0.3066NA NA NA NA WCM0_LM1 20 35736994 45717954 0.2515 0.0353 1.0344 1.015 1 1WCM0_LM1 20 45725823 50713685 0.0399 −0.1881 0.8908 0.8647 1 1 WCM0_LM120 50713876 62076120 0.3031 0.0895 1.0718 1.0561 1 1 WCM0_LM1 2062076743 62680578 0.0518 −0.1755 0.8986 0.8723 1 1 WCM0_LM1 20 6269474562904845 0.3983 0.1892 NA NA NA NA WCM0_LM1 21 10862618 32493031 0.39380.1845 1.1471 1.1257 1 1 WCM0_LM1 21 32496847 36088769 0.1727 −0.04780.996 0.9389 1 1 WCM0_LM1 21 36164321 37518393 −0.7305 −1.0209 NA NA NANA WCM0_LM1 21 37518756 38516988 0.0896 −0.1355 0.9354 0.8853 1 1WCM0_LM1 21 38519818 48084196 0.3381 0.1262 1.104 1.0788 1 1 WCM0_LM1 2216255826 31724813 −0.7461 −1.0382 0.9779 −0.0041 1 0 WCM0_LM1 2231731671 32352743 −1.0116 −1.3355 NA NA NA NA WCM0_LM1 22 3243554237964801 −0.7354 −1.0263 0.9889 −0.007 1 0 WCM0_LM1 22 37966313 43465814−0.9201 −1.2323 0.8642 −0.0129 1 0 WCM0_LM1 22 43471514 51216346 −0.7478−1.0401 0.9713 0.0013 1 0 WCM0_LM1 3 361508 9290619 −0.5025 −0.77051.1669 0.0055 1 0 WCM0_LM1 3 9406820 10331825 −0.8686 −1.1746 0.895−0.009 1 0 WCM0_LM1 3 10342986 31789625 −0.5926 −0.869 1.0937 0.0014 1 0WCM0_LM1 3 31871595 33704926 −0.8281 −1.1293 NA NA NA NA WCM0_LM1 333725922 47058770 −0.5697 −0.844 1.112 0.0022 1 0 WCM0_LM1 3 4705912650369546 −0.8735 −1.18 0.8993 −0.0166 1 0 WCM0_LM1 3 50374568 53381376−0.683 −0.9684 1.0342 −0.012 1 0 WCM0_LM1 3 53529174 56605295 −0.4625−0.727 1.1992 0.0091 1 0 WCM0_LM1 3 56627002 62110081 −0.8075 −1.10630.9418 −0.0128 1 0 WCM0_LM1 3 62118295 68788363 −0.4322 −0.6941 1.2372−0.001 1 0 WCM0_LM1 3 68802029 73673315 −0.6562 −0.9389 1.0293 0.014 1 0WCM0_LM1 3 73673686 74570191 0.9047 0.7152 NA NA NA NA WCM0_LM1 375386371 93761981 0.2481 0.0316 1.0415 1.0028 1 1 WCM0_LM1 3 93768279122121578 −0.5861 −0.8619 1.0928 0.0077 1 0 WCM0_LM1 3 122123173122255087 0.1987 −0.0203 NA NA NA NA WCM0_LM1 3 122255221 1412351730.327 0.1145 1.0826 1.0826 1 1 WCM0_LM1 3 141248605 142525070 0.1045−0.1197 0.9252 0.9155 1 1 WCM0_LM1 3 142537271 169487151 0.3684 0.15791.1239 1.1075 1 1 WCM0_LM1 3 169492249 170185011 0.0536 −0.1736 0.8960.8772 1 1 WCM0_LM1 3 170185177 182563258 0.2667 0.0512 1.0546 1.0176 11 WCM0_LM1 3 182566359 186793363 0.1198 −0.1035 0.9367 0.9249 1 1WCM0_LM1 3 186793617 194081657 0.4134 0.205 1.1756 1.1298 1 1 WCM0_LM1 3194081782 197847281 0.0649 −0.1616 0.9007 0.8874 1 1 WCM0_LM1 4 53435437770 0.0436 −0.1841 NA NA NA NA WCM0_LM1 4 438219 3225686 −0.2187−0.4638 0.9545 0.4956 1 0 WCM0_LM1 4 3227429 38995310 −0.0642 −0.29871.0692 0.5567 1 1 WCM0_LM1 4 38995574 41270007 −0.4707 −0.7359 0.79240.4084 1 0 WCM0_LM1 4 41362851 44631587 −1.3791 −1.7597 0.582 0.0086 1 0WCM0_LM1 4 44637960 62933928 −0.1185 −0.3565 1.022 0.5401 1 1 WCM0_LM1 462935916 71522102 0.3653 0.1546 1.1201 1.1061 1 1 WCM0_LM1 4 7152296271895110 0.0663 −0.1601 NA NA NA NA WCM0_LM1 4 72102311 73615956 −0.4998−0.7676 NA NA NA NA WCM0_LM1 4 73924000 75971468 0.3942 0.1849 NA NA NANA WCM0_LM1 4 76407858 77357396 0.1413 −0.0808 0.9615 0.9295 1 1WCM0_LM1 4 77476824 82378694 0.3945 0.1852 1.1429 1.131 1 1 WCM0_LM1 482380520 84518094 0.066 −0.1605 0.9222 0.8672 1 1 WCM0_LM1 4 84518575106158383 0.3088 0.0955 1.0819 1.0549 1 1 WCM0_LM1 4 106158540 106474017−0.5903 −0.8665 NA NA NA NA WCM0_LM1 4 106510485 177073042 0.2991 0.08531.0709 1.0509 1 1 WCM0_LM1 4 177077291 178911613 −0.6376 −0.9184 NA NANA NA WCM0_LM1 4 183090475 190947586 0.056 −0.171 0.9211 0.8553 1 1WCM0_LM1 5 140526 192227 0.1483 −0.0734 NA NA NA NA WCM0_LM1 5 19253916465682 0.021 −0.2082 1.1494 0.5819 1 1 WCM0_LM1 5 16474924 68390019−0.0943 −0.3308 1.0681 0.5221 1 1 WCM0_LM1 5 68396773 68805616 −0.466−0.7308 NA NA NA NA WCM0_LM1 5 70308462 81460177 −0.1124 −0.3501 1.03570.5334 1 1 WCM0_LM1 5 81474368 87962746 0.0532 −0.1741 1.184 0.5887 1 1WCM0_LM1 5 88018483 122950033 0.3675 0.1569 1.1219 1.1079 1 1 WCM0_LM1 5123966364 132160881 −0.5864 −0.8622 1.1076 −0.0074 1 0 WCM0_LM1 5132161095 134223668 −0.8333 −1.1351 NA NA NA NA WCM0_LM1 5 134223862135583202 −0.3956 −0.6544 1.2572 0.0134 1 0 WCM0_LM1 5 135583453139006308 0.0137 −0.2159 0.8647 0.8574 1 1 WCM0_LM1 5 139060264146657755 0.3278 0.1153 1.0855 1.0809 1 1 WCM0_LM1 5 146658785 1486820320.4773 0.2717 1.2186 1.1959 1 1 WCM0_LM1 5 148685952 170610418 0.28410.0695 1.0526 1.046 1 1 WCM0_LM1 5 170626763 180166787 0.1416 −0.08050.9547 0.9367 1 1 WCM0_LM1 5 180166887 180687725 0.2885 0.0741 NA NA NANA WCM0_LM1 6 292598 17283043 0.2985 0.0846 1.0682 1.0526 1 1 WCM0_LM1 617284886 18258589 0.0401 −0.1879 NA NA NA NA WCM0_LM1 6 1826420530314223 0.2997 0.0858 1.0702 1.0524 1 1 WCM0_LM1 6 30314598 374388260.1439 −0.0781 0.9543 0.9403 1 1 WCM0_LM1 6 37439651 41739604 0.36110.1503 1.1167 1.1028 1 1 WCM0_LM1 6 41740715 43648794 0.0587 −0.16820.9022 0.8777 1 1 WCM0_LM1 6 43655425 44344794 0.2738 0.0587 1.06011.0229 1 1 WCM0_LM1 6 44355554 71012669 0.407 0.1983 1.1557 1.1389 1 1WCM0_LM1 6 71138060 86197149 0.2871 0.0726 1.0759 1.0274 1 1 WCM0_LM1 686199244 97730193 0.1319 −0.0908 1.0441 0.8339 1 1 WCM0_LM1 6 99282878118972442 0.3109 0.0976 1.0756 1.0644 1 1 WCM0_LM1 6 119221953 121768884−0.0998 −0.3366 NA NA NA NA WCM0_LM1 6 122720909 125144312 0.3713 0.1609NA NA NA NA WCM0_LM1 6 125231491 149395235 −0.0414 −0.2744 1.0941 0.55941 1 WCM0_LM1 6 149691121 151914421 −0.3073 −0.5591 0.9025 0.4549 1 0WCM0_LM1 6 151917646 166755975 −0.0931 −0.3295 1.0512 0.5404 1 1WCM0_LM1 6 166778939 170893364 0.3954 0.1861 1.1579 1.1175 1 1 WCM0_LM17 193625 4876274 0.1425 −0.0796 0.9543 0.9384 1 1 WCM0_LM1 7 48997626859485 −0.0828 −0.3185 0.813 0.7908 1 1 WCM0_LM1 7 7118626 271961100.361 0.1502 1.1271 1.0923 1 1 WCM0_LM1 7 27203195 27689282 −0.4766−0.7423 NA NA NA NA WCM0_LM1 7 27702390 29160547 0.3915 0.1821 NA NA NANA WCM0_LM1 7 29394282 38398370 −0.5081 −0.7766 1.1711 −0.0036 1 0WCM0_LM1 7 38402533 39446346 0.4171 0.2089 NA NA NA NA WCM0_LM1 739472846 45614312 0.2275 0.01 1.0239 0.99 1 1 WCM0_LM1 7 4561470755588806 0.4368 0.2294 1.176 1.1687 1 1 WCM0_LM1 7 55750416 77584134−0.0049 −0.2357 0.9097 0.7889 1 1 WCM0_LM1 7 77648671 91502985 0.40460.1957 1.1561 1.1345 1 1 WCM0_LM1 7 91503279 92151435 0.1573 −0.0639 NANA NA NA WCM0_LM1 7 92157802 97363550 0.423 0.2151 1.1692 1.1523 1 1WCM0_LM1 7 97364132 102553714 −0.0445 −0.2777 0.9434 0.7064 1 1 WCM0_LM17 102566827 108138018 0.231 0.0137 1.0201 0.9989 1 1 WCM0_LM1 7108142930 127847936 0.3859 0.1763 1.143 1.1169 1 1 WCM0_LM1 7 127892093129950740 0.0944 −0.1304 0.9319 0.8952 1 1 WCM0_LM1 7 129951972137612947 0.3068 0.0934 1.0803 1.0534 1 1 WCM0_LM1 7 137686437 1406243870.0705 −0.1557 0.9015 0.8939 1 1 WCM0_LM1 7 140706285 142649654 0.54060.3378 1.6943 0.8333 2 1 WCM0_LM1 7 142650982 146829590 0.3421 0.13041.1175 1.0716 1 1 WCM0_LM1 7 146997203 148950613 0.0287 −0.2 0.88810.853 1 1 WCM0_LM1 7 148950958 158727128 0.2749 0.0598 1.0511 1.0336 1 1WCM0_LM1 7 158734759 158937481 0.5733 0.3718 NA NA NA NA WCM0_LM1 8192966 2092855 −3.7508 −6.0981 NA NA NA NA WCM0_LM1 8 2796244 36698474−0.2129 −0.4575 1.4622 −0.0058 1 0 WCM0_LM1 8 36703313 38265720 0.2860.0715 NA NA NA NA WCM0_LM1 8 38271278 41792140 0.4917 0.2868 1.38541.0545 1 1 WCM0_LM1 8 41792390 48962477 0.2676 0.0522 NA NA NA NAWCM0_LM1 8 49637377 67342273 0.5629 0.361 1.3859 1.1827 1 1 WCM0_LM1 867342432 68204341 0.2589 0.0431 NA NA NA NA WCM0_LM1 8 68208787 952727060.5545 0.3523 1.3909 1.1622 1 1 WCM0_LM1 8 95384432 105601109 0.40980.2012 1.3132 0.9862 1 1 WCM0_LM1 8 106430837 120577219 −0.1567 −0.39741.5142 0.0042 2 0 WCM0_LM1 8 120580405 131414198 −0.336 −0.59 1.32834.00E−04 1 0 WCM0_LM1 8 131792801 144295844 −0.1572 −0.3979 1.51370.0042 2 0 WCM0_LM1 8 144297004 146032606 −0.4141 −0.6744 1.2623 −0.00921 0 WCM0_LM1 8 146032923 146279368 −0.17 −0.4117 NA NA NA NA WCM0_LM1 9117666 3395441 −1.4181 −1.8058 0.5789 −0.0069 1 0 WCM0_LM1 9 382831319032907 −0.0195 −0.2512 1.1339 0.5465 1 1 WCM0_LM1 9 19049638 19550190−0.7882 −1.0849 NA NA NA NA WCM0_LM1 9 19573446 32784838 −0.4504 −0.71391.2124 0.007 1 0 WCM0_LM1 9 32973565 39456961 −0.6113 −0.8895 1.0824−0.0029 1 0 WCM0_LM1 9 40293070 99417036 −0.0913 −0.3276 1.0815 0.5123 11 WCM0_LM1 9 99521250 114090419 0.3308 0.1185 1.0935 1.0776 1 1 WCM0_LM19 114090711 116267769 0.1428 −0.0793 0.9615 0.9316 1 1 WCM0_LM1 9116268683 123230115 0.4589 0.2526 1.2075 1.1752 1 1 WCM0_LM1 9 123232440127302282 0.2903 0.076 1.0641 1.0441 1 1 WCM0_LM1 9 127306068 1308306610.1164 −0.1071 0.9402 0.9167 1 1 WCM0_LM1 9 130830895 133072162 −0.0393−0.2722 0.8325 0.8237 1 1 WCM0_LM1 9 133327655 135254526 0.1056 −0.11860.9211 0.9211 1 1 WCM0_LM1 9 135261999 139405204 0.2839 0.0693 1.06351.0349 1 1 WCM0_LM1 9 139405684 140695312 0.1359 −0.0865 0.9557 0.9279 11 WCM0_LM1 9 140706066 141071438 0.4125 0.2041 NA NA NA NA WCM0_LM1 X2700159 17820046 0.305 0.0914 NA NA NA NA WCM0_LM1 X 18183275 247452090.1243 −0.0988 NA NA NA NA WCM0_LM1 X 24745986 40534530 0.3688 0.1583 NANA NA NA WCM0_LM1 X 40539076 49595690 0.0625 −0.1642 NA NA NA NAWCM0_LM1 X 49597215 70288184 0.2935 0.0794 NA NA NA NA WCM0_LM1 X70316613 70836559 −0.0036 −0.2343 NA NA NA NA WCM0_LM1 X 70836914101091121 0.2548 0.0387 NA NA NA NA WCM0_LM1 X 101091727 1109244780.4425 0.2354 NA NA NA NA WCM0_LM1 X 110925433 124097582 0.1373 −0.0851NA NA NA NA WCM0_LM1 X 125298700 140926085 0.8143 0.6218 NA NA NA NAWCM0_LM1 X 140953207 152226437 1.0529 0.8679 NA NA NA NA WCM0_LM1 X152721728 154509348 0.777 0.5832 NA NA NA NA WCM0_LM2 1 809001 11907304−0.1504 −0.4673 0.9651 0.4816 1 0 WCM0_LM2 1 11907604 19609254 −0.6974−1.0532 0.9688 −0.005 1 0 WCM0_LM2 1 19611241 29652177 −0.1841 −0.5030.9478 0.4635 1 0 WCM0_LM2 1 31186427 31898727 0.6138 0.3307 NA NA NA NAWCM0_LM2 1 31899500 32279901 0.8115 0.5345 NA NA NA NA WCM0_LM2 132280190 33613323 0.5582 0.2732 1.5348 0.8822 2 1 WCM0_LM2 1 3362387635370912 0.9322 0.6585 NA NA NA NA WCM0_LM2 1 35452725 41215223 0.60440.321 1.5383 0.96 2 1 WCM0_LM2 1 41218830 44778831 0.7638 0.4854 1.73581.064 2 1 WCM0_LM2 1 44785423 46775911 0.6076 0.3243 NA NA NA NAWCM0_LM2 1 46806558 50310441 0.7974 0.52 1.7571 1.1108 2 1 WCM0_LM2 150569670 50886936 0.5996 0.316 NA NA NA NA WCM0_LM2 1 50907098 535163560.2081 −0.0906 NA NA NA NA WCM0_LM2 1 53527948 62149124 0.493 0.20571.1999 1.1067 1 1 WCM0_LM2 1 62160464 64011649 0.2268 −0.0711 0.99460.9092 1 1 WCM0_LM2 1 64017384 91182664 0.4455 0.1564 1.1249 1.1041 1 1WCM0_LM2 1 91382527 120612005 −0.5836 −0.9299 1.0518 −0.002 1 0 WCM0_LM21 120612265 151752497 −0.2417 −0.564 0.8667 0.4861 1 0 WCM0_LM2 1151752629 153516409 0.0213 −0.2863 1.113 0.527 1 1 WCM0_LM2 1 153516420156813181 −0.2486 −0.5714 0.8874 0.4586 1 0 WCM0_LM2 1 156814048160793962 −0.0016 −0.3103 1.0405 0.5724 1 1 WCM0_LM2 1 160797514161565408 −0.2371 −0.5592 NA NA NA NA WCM0_LM2 1 161569620 205814681−0.0361 −0.3467 1.0042 0.5686 1 1 WCM0_LM2 1 205817056 210329130 0.0813−0.2234 1.0533 0.6599 1 1 WCM0_LM2 1 210334068 233193025 −0.063 −0.37510.9824 0.5598 1 1 WCM0_LM2 1 233225848 233394410 −0.5806 −0.9267 NA NANA NA WCM0_LM2 1 233394765 249212579 −0.1496 −0.4665 0.9097 0.5377 1 1WCM0_LM2 10 225958 5690932 −0.4939 −0.8333 1.128 −0.0055 1 0 WCM0_LM2 105693162 44112746 −0.6941 −1.0496 0.9711 −0.0049 1 0 WCM0_LM2 10 4413946164565615 −0.5075 −0.8479 1.1045 0.0067 1 0 WCM0_LM2 10 64572919 70998887−0.8897 −1.2634 0.8482 −0.0151 1 0 WCM0_LM2 10 71000439 101162362−0.6174 −0.9664 1.0265 −0.0029 1 0 WCM0_LM2 10 101163194 105218359−0.7465 −1.1066 0.9401 −0.0113 1 0 WCM0_LM2 10 105254210 120460855−0.542 −0.885 1.0838 −8.00E−04  1 0 WCM0_LM2 10 120467023 123844974−0.7122 −1.0692 0.9741 −0.0209 1 0 WCM0_LM2 10 123845139 135373606−0.5134 −0.8543 1.1003 0.0059 1 0 WCM0_LM2 11 193096 1861131 −0.6894−1.0445 0.9687 0.001 1 0 WCM0_LM2 11 1861799 4185599 −0.5767 −0.92251.057 −0.0018 1 0 WCM0_LM2 11 4388724 8118404 −0.4196 −0.7537 1.18340.0028 1 0 WCM0_LM2 11 8118761 45991385 −0.5332 −0.8756 1.0906−6.00E−04  1 0 WCM0_LM2 11 45992748 55322837 −0.7428 −1.1025 0.932−6.00E−04  1 0 WCM0_LM2 11 55339702 60899554 −0.5585 −0.9029 1.0704−7.00E−04  1 0 WCM0_LM2 11 60899832 69487993 −0.6937 −1.0491 0.9767−0.0102 1 0 WCM0_LM2 11 69489926 106849520 0.36 0.0676 1.0491 1.0469 1 1WCM0_LM2 11 106856799 110134872 0.1743 −0.1259 0.9375 0.8953 1 1WCM0_LM2 11 110135573 116824829 0.3637 0.0715 1.0912 1.0104 1 1 WCM0_LM211 116827661 117150687 −0.7129 −1.07 NA NA NA NA WCM0_LM2 11 117150893118656800 −0.0634 −0.3754 1.009 0.5328 1 1 WCM0_LM2 11 118754629119020937 −0.772 −1.1343 NA NA NA NA WCM0_LM2 11 119024934 1342574530.3883 0.0971 1.0718 1.0674 1 1 WCM0_LM2 12 247582 459826 −0.5089−0.8494 NA NA NA NA WCM0_LM2 12 461326 1740480 −0.7931 −1.1574 0.88830.0083 1 0 WCM0_LM2 12 1741845 6155858 −0.5146 −0.8555 1.106 −7.00E−04 1 0 WCM0_LM2 12 6161693 9225264 −0.738 −1.0973 0.9408 −0.006 1 0WCM0_LM2 12 9227195 9578319 −0.5413 −0.8843 NA NA NA NA WCM0_LM2 129659718 9713413 0.3602 0.0679 NA NA NA NA WCM0_LM2 12 9723417 18241826−0.5684 −0.9135 1.0623 −4.00E−04  1 0 WCM0_LM2 12 18242148 20905250−1.3071 −1.73 NA NA NA NA WCM0_LM2 12 20905494 21069133 −0.4659 −0.8033NA NA NA NA WCM0_LM2 12 21168677 22837880 −1.357 −1.7869 0.5682 0.0114 10 WCM0_LM2 12 23687201 24365376 −0.2943 −0.62 NA NA NA NA WCM0_LM2 1224736749 25348052 −1.4386 −1.8807 NA NA NA NA WCM0_LM2 12 2535691628605426 −0.0099 −0.3191 1.0394 0.5638 1 1 WCM0_LM2 12 28637090 314358310.3937 0.1026 1.1239 1.0235 1 1 WCM0_LM2 12 31440687 32908129 0.0869−0.2174 0.8953 0.8249 1 1 WCM0_LM2 12 32908360 40761516 0.3641 0.0719 NANA NA NA WCM0_LM2 12 41302275 41337822 −0.2409 −0.5632 NA NA NA NAWCM0_LM2 12 41352954 48743770 −0.464 −0.8012 1.1371 0.0107 1 0 WCM0_LM212 48866585 51757916 −0.6938 −1.0493 0.9682 −0.0018 1 0 WCM0_LM2 1251758127 53298685 −0.4231 −0.7574 1.1862 −0.003 1 0 WCM0_LM2 12 5329877554107503 −0.6992 −1.0551 0.9801 −0.0176 1 0 WCM0_LM2 12 5410792956078966 −0.5129 −0.8537 NA NA NA NA WCM0_LM2 12 56079067 57181011−0.7208 −1.0786 0.9758 −0.0288 1 0 WCM0_LM2 12 57317619 77240448 −0.5494−0.8931 1.0838 −0.0069 1 0 WCM0_LM2 12 77242040 93157851 −0.446 −0.78191.1525 0.0107 1 0 WCM0_LM2 12 93162860 110240989 −0.5939 −0.941 1.044−0.0023 1 0 WCM0_LM2 12 110246195 112915456 −0.8319 −1.1999 NA NA NA NAWCM0_LM2 12 112915755 120582744 −0.6181 −0.9672 1.0259 −0.0029 1 0WCM0_LM2 12 120583045 124303507 −0.7965 −1.1612 0.9105 −0.0162 1 0WCM0_LM2 12 124303750 133779296 −0.5908 −0.9376 1.0464 −0.0022 1 0WCM0_LM2 13 19705463 61989209 −0.5704 −0.9157 1.0618 −0.0016 1 0WCM0_LM2 13 63745874 70681840 −1.2897 −1.7102 NA NA NA NA WCM0_LM2 1372014840 73637958 −0.4773 −0.8155 NA NA NA NA WCM0_LM2 13 7364984280911767 −0.3128 −0.6396 1.2762 0.0075 1 0 WCM0_LM2 13 84453597115089411 0.5121 0.2254 2.3436 −0.0053 2 0 WCM0_LM2 14 19553736 206922910.2546 −0.0421 0.9946 0.948 1 1 WCM0_LM2 14 20692574 22180535 0.1361−0.1659 0.8988 0.8839 1 1 WCM0_LM2 14 22180788 23057900 0.3578 0.06541.0681 1.0246 1 1 WCM0_LM2 14 23067224 23745364 0.0894 −0.2148 0.87250.8508 1 1 WCM0_LM2 14 23745512 31188516 0.2959 0.001 1.0142 0.9871 1 1WCM0_LM2 14 31191060 51190262 0.0844 −0.2201 0.8657 0.8513 1 1 WCM0_LM214 51190398 73238595 0.2306 −0.0671 0.9605 0.9486 1 1 WCM0_LM2 1473360818 75747783 0.0306 −0.2765 0.8256 0.8256 1 1 WCM0_LM2 14 7574809895267286 0.1876 −0.1121 0.931 0.9194 1 1 WCM0_LM2 14 95556866 95599710−0.6663 −1.0194 NA NA NA NA WCM0_LM2 14 95658021 102028638 0.3373 0.0441.0621 0.9999 1 1 WCM0_LM2 14 102228256 107283105 0.1716 −0.1288 0.96240.8668 1 1 WCM0_LM2 15 20169960 40764530 0.3199 0.0259 1.104 0.9323 1 1WCM0_LM2 15 40846235 42058949 0.0588 −0.2469 NA NA NA NA WCM0_LM2 1542059002 42491761 0.3235 0.0297 1.0399 1.0017 1 1 WCM0_LM2 15 4249211945142593 0.1543 −0.1468 NA NA NA NA WCM0_LM2 15 45206957 50339654 0.39010.099 1.0955 1.0465 1 1 WCM0_LM2 15 50366340 59974617 0.2178 −0.08060.9457 0.9457 1 1 WCM0_LM2 15 60297219 63967333 0.3632 0.071 1.10180.9991 1 1 WCM0_LM2 15 63970196 66853583 0.1355 −0.1665 NA NA NA NAWCM0_LM2 15 66855944 102359217 0.2825 −0.013 0.9941 0.9879 1 1 WCM0_LM216 79642 3274032 −0.6544 −1.0065 1.0048 −0.0093 1 0 WCM0_LM2 16 327426447252861 −0.7855 −1.1491 0.9139 −0.0121 1 0 WCM0_LM2 16 4727195767360773 −0.6283 −0.9782 1.0162 −0.001 1 0 WCM0_LM2 16 67375880 70594429−0.7866 −1.1503 0.9127 −0.0116 1 0 WCM0_LM2 16 70595639 90162210 −0.6527−1.0046 1.0007 −0.0039 1 0 WCM0_LM2 17 131595 7579831 0.1595 −0.14150.9104 0.9028 1 1 WCM0_LM2 17 7592149 7951793 −0.6695 −1.0229 NA NA NANA WCM0_LM2 17 7976111 8647931 −0.1607 −0.4782 0.9731 0.4627 1 0WCM0_LM2 17 8700793 28029992 0.1877 −0.112 0.9824 0.8683 1 1 WCM0_LM2 1728120878 28773021 0.7147 0.4348 NA NA NA NA WCM0_LM2 17 2877665647501985 −0.7385 −1.0978 0.9456 −0.0111 1 0 WCM0_LM2 17 4757277456647766 −0.6128 −0.9615 1.0299 −0.0028 1 0 WCM0_LM2 17 5664942659857643 −0.7997 −1.1646 0.9031 −0.0109 1 0 WCM0_LM2 17 5985825472954993 0.211 −0.0876 0.9529 0.9293 1 1 WCM0_LM2 17 72955118 769688180.128 −0.1744 0.8917 0.8806 1 1 WCM0_LM2 17 76969185 81052333 0.2439−0.0532 0.9678 0.9597 1 1 WCM0_LM2 18 47641 14613577 0.8024 0.52511.9069 0.9711 2 1 WCM0_LM2 18 18539788 22672060 −0.7723 −1.1347 0.9366−0.0258 1 0 WCM0_LM2 18 22775185 74980776 −0.543 −0.8862 1.083−9.00E−04  1 0 WCM0_LM2 18 74980877 77287496 0.8278 0.5512 NA NA NA NAWCM0_LM2 18 77439995 78005214 −0.5101 −0.8507 NA NA NA NA WCM0_LM2 19281360 327207 0.3508 0.0581 NA NA NA NA WCM0_LM2 19 327997 63742600.1212 −0.1815 0.8892 0.8744 1 1 WCM0_LM2 19 6374445 7809842 0.38370.0923 1.3042 0.8279 1 1 WCM0_LM2 19 7810668 8203328 0.9435 0.6701 2.3570.8254 2 1 WCM0_LM2 19 8206559 8326982 0.8088 0.5317 NA NA NA NAWCM0_LM2 19 8367282 8495625 0.2638 −0.0326 1.1612 0.7942 1 1 WCM0_LM2 198503458 9771427 0.8897 0.6149 2.2409 0.822 2 1 WCM0_LM2 19 980143410504058 0.338 0.0448 1.1957 0.8673 1 1 WCM0_LM2 19 10505720 106924060.8764 0.6012 NA NA NA NA WCM0_LM2 19 10694364 11326479 1.2658 1 3.24740.7525 3 1 WCM0_LM2 19 11327571 11348379 0.9272 0.6533 NA NA NA NAWCM0_LM2 19 11348911 11598567 0.3782 0.0865 NA NA NA NA WCM0_LM2 1911606822 12089946 1.2131 0.9461 NA NA NA NA WCM0_LM2 19 1212578812637726 0.2532 −0.0436 NA NA NA NA WCM0_LM2 19 12637834 12886188 0.91480.6406 NA NA NA NA WCM0_LM2 19 12902697 14703188 0.4454 0.1563 1.24740.9815 1 1 WCM0_LM2 19 14705373 15221187 0.8715 0.5961 2.2231 0.8002 2 1WCM0_LM2 19 15221544 15853070 0.4415 0.1523 1.342 0.8807 1 1 WCM0_LM2 1915882836 16222893 0.9507 0.6774 2.3673 0.8313 2 1 WCM0_LM2 19 1622900816436714 0.3393 0.0461 NA NA NA NA WCM0_LM2 19 16437661 16551608 0.91190.6376 NA NA NA NA WCM0_LM2 19 16552721 17213366 0.3713 0.0794 1.24110.8721 1 1 WCM0_LM2 19 17256273 18085936 0.8722 0.5969 2.2352 0.7898 2 1WCM0_LM2 19 18092703 18530494 1.3071 1.0421 3.263 0.8554 3 1 WCM0_LM2 1918538157 18870989 1.014 0.7424 2.4445 0.9014 2 1 WCM0_LM2 19 1887630919011238 0.4846 0.197 NA NA NA NA WCM0_LM2 19 19014125 19310047 0.96830.6956 2.382 0.857 2 1 WCM0_LM2 19 19312537 19681630 1.3499 1.08573.3842 0.8608 3 1 WCM0_LM2 19 19710129 20003109 0.9761 0.7036 NA NA NANA WCM0_LM2 19 20003272 33200249 0.3451 0.0522 1.3938 0.6798 1 1WCM0_LM2 19 33202813 33701353 −0.3655 −0.6958 0.8296 0.4052 1 0 WCM0_LM219 33701812 35263693 0.6075 0.3241 NA NA NA NA WCM0_LM2 19 3542084135660525 −0.0949 −0.4086 0.9831 0.5236 1 1 WCM0_LM2 19 35715740 359785670.5806 0.2963 1.5315 0.9246 2 1 WCM0_LM2 19 35979523 36435937 −0.2359−0.5579 NA NA NA NA WCM0_LM2 19 36486436 36530798 0.5509 0.2656 NA NA NANA WCM0_LM2 19 36545051 36728204 −0.3637 −0.694 NA NA NA NA WCM0_LM2 1936831136 36896567 0.256 −0.0406 NA NA NA NA WCM0_LM2 19 3689886437006131 −0.6925 −1.0479 NA NA NA NA WCM0_LM2 19 37037960 387468940.4726 0.1846 1.4746 0.7984 1 1 WCM0_LM2 19 38755533 38845439 −0.3094−0.636 NA NA NA NA WCM0_LM2 19 38847156 38886271 0.5556 0.2704 NA NA NANA WCM0_LM2 19 38886526 38912586 −0.1959 −0.5155 NA NA NA NA WCM0_LM2 1938916756 39138447 0.5188 0.2324 1.4217 0.9278 1 1 WCM0_LM2 19 3919121039522789 −0.3243 −0.6519 NA NA NA NA WCM0_LM2 19 39575916 407629690.5604 0.2755 1.5648 0.8561 2 1 WCM0_LM2 19 40771119 40978551 −0.2495−0.5724 NA NA NA NA WCM0_LM2 19 40993675 41063170 0.5773 0.293 NA NA NANA WCM0_LM2 19 41066221 41271087 −0.2348 −0.5567 NA NA NA NA WCM0_LM2 1941281554 41332543 0.6147 0.3316 NA NA NA NA WCM0_LM2 19 4135068641450715 −0.207 −0.5272 NA NA NA NA WCM0_LM2 19 41497353 41633884 0.5190.2326 NA NA NA NA WCM0_LM2 19 41699292 41863777 −0.2368 −0.5589 NA NANA NA WCM0_LM2 19 41869392 42133329 0.6507 0.3688 1.5579 1.0247 2 1WCM0_LM2 19 42181360 42392792 −0.0622 −0.3742 NA NA NA NA WCM0_LM2 1942396179 42598073 0.6228 0.34 NA NA NA NA WCM0_LM2 19 42599640 427306000.0519 −0.2542 NA NA NA NA WCM0_LM2 19 42736267 42848993 −4.3138 −9.9291NA NA NA NA WCM0_LM2 19 42853725 43032546 0.0238 −0.2837 NA NA NA NAWCM0_LM2 19 43087484 43236931 −1.4938 −1.9445 NA NA NA NA WCM0_LM2 1943237172 43910649 0.0562 −0.2496 1.7062 −0.024 2 0 WCM0_LM2 19 4392003644174085 −1.6371 −2.1122 NA NA NA NA WCM0_LM2 19 44222890 447338910.6261 0.3434 1.6002 0.9372 2 1 WCM0_LM2 19 44739091 45349799 0.97090.6982 2.2914 0.9535 2 1 WCM0_LM2 19 45368497 46112999 0.4795 0.19171.341 0.9432 1 1 WCM0_LM2 19 46116816 46216642 1.0285 0.7573 NA NA NA NAWCM0_LM2 19 46268872 46367703 0.5708 0.2862 NA NA NA NA WCM0_LM2 1946375421 46879824 −0.2194 −0.5404 0.9188 0.4564 1 0 WCM0_LM2 19 4688661247353975 0.5132 0.2266 NA NA NA NA WCM0_LM2 19 47421971 47774907 −0.2455−0.5681 NA NA NA NA WCM0_LM2 19 47813165 48949595 0.4546 0.1659 1.42670.817 1 1 WCM0_LM2 19 48949766 49016442 0.5572 0.2722 NA NA NA NAWCM0_LM2 19 49055587 49611643 −0.2577 −0.5811 0.8716 0.4654 1 0 WCM0_LM219 49618175 49813726 0.5037 0.2168 NA NA NA NA WCM0_LM2 19 4981438450885847 −0.2731 −0.5974 0.8802 0.4417 1 0 WCM0_LM2 19 50902264 511911930.5377 0.252 NA NA NA NA WCM0_LM2 19 51192067 51658582 1.0986 0.8292.6982 0.8547 3 1 WCM0_LM2 19 51714527 52550080 0.6571 0.3753 1.67470.9196 2 1 WCM0_LM2 19 52618044 52633797 0.4371 0.1478 NA NA NA NAWCM0_LM2 19 52658405 52723015 −0.1815 −0.5003 NA NA NA NA WCM0_LM2 1952723436 52937271 0.4464 0.1574 NA NA NA NA WCM0_LM2 19 5293829554567035 −0.2621 −0.5858 0.8617 0.4709 1 0 WCM0_LM2 19 54610127 551794410.6446 0.3625 1.7143 0.8569 2 1 WCM0_LM2 19 55286669 56206477 −0.2632−0.5869 0.8822 0.4493 1 0 WCM0_LM2 19 56220245 56935545 0.5039 0.2171.4849 0.8396 1 1 WCM0_LM2 19 56952645 57325655 −0.0895 −0.403 0.96460.548 1 1 WCM0_LM2 19 57326077 58439306 0.4424 0.1533 1.2863 0.9379 1 1WCM0_LM2 19 58441804 59082661 −0.0393 −0.3501 1.0712 0.4979 1 0 WCM0_LM22 41647 21266460 −0.0169 −0.3265 1.056 0.539 1 1 WCM0_LM2 2 2397493829432678 −0.1904 −0.5097 0.9122 0.4926 1 0 WCM0_LM2 2 29436953 316259670.0138 −0.2942 1.071 0.5601 1 1 WCM0_LM2 2 31628860 44589177 −0.2338−0.5556 0.8955 0.4652 1 0 WCM0_LM2 2 44599846 55277374 −0.0386 −0.34931.0329 0.537 1 1 WCM0_LM2 2 55402980 63815423 −0.2346 −0.5565 0.91160.4483 1 0 WCM0_LM2 2 63816121 68274489 −0.0746 −0.3872 0.9895 0.5396 11 WCM0_LM2 2 68352450 69784064 0.4272 0.1375 1.1217 1.0783 1 1 WCM0_LM22 69870168 91766588 −0.6733 −1.0269 0.9859 −0.0044 1 0 WCM0_LM2 291777703 101619136 0.2574 −0.0392 0.9864 0.96 1 1 WCM0_LM2 2 101620767112942904 −0.125 −0.4404 0.9931 0.4808 1 0 WCM0_LM2 2 112944630116257108 −0.6158 −0.9647 1.0249 −1.00E−04  1 0 WCM0_LM2 2 116283478118578918 −0.1449 −0.4615 NA NA NA NA WCM0_LM2 2 118579252 1206900750.243 −0.0542 0.9872 0.939 1 1 WCM0_LM2 2 120692535 149501148 −0.7183−1.0759 0.9543 −0.0055 1 0 WCM0_LM2 2 149511523 160811874 0.3254 0.03171.0296 1.0147 1 1 WCM0_LM2 2 160812225 170145592 0.4488 0.1599 1.13221.1021 1 1 WCM0_LM2 2 170147342 179391714 0.2926 −0.0025 1.0087 0.9879 11 WCM0_LM2 2 179392019 182543506 0.5387 0.253 1.2176 1.1658 1 1 WCM0_LM22 182756817 201680462 0.3218 0.0279 1.028 1.011 1 1 WCM0_LM2 2 201681077204599484 0.1057 −0.1977 0.8756 0.8683 1 1 WCM0_LM2 2 204732693219029690 0.3459 0.053 1.0449 1.0298 1 1 WCM0_LM2 2 219029752 2196921330.1526 −0.1486 0.9087 0.8955 1 1 WCM0_LM2 2 219692363 223918019 0.32960.036 1.0423 1.0082 1 1 WCM0_LM2 2 224462246 230744708 −0.1511 −0.46810.9232 0.5226 1 1 WCM0_LM2 2 230787332 234343433 −0.754 −1.1148 0.9274−0.0039 1 0 WCM0_LM2 2 234344510 234656640 −0.0639 −0.376 1.0232 0.518 11 WCM0_LM2 2 234669142 234858807 0.0459 −0.2605 NA NA NA NA WCM0_LM2 2234862657 242021201 0.3767 0.085 1.075 1.0464 1 1 WCM0_LM2 2 242021730242815417 0.1983 −0.1009 0.9529 0.912 1 1 WCM0_LM2 20 68427 6021946−0.1052 −0.4195 1.0074 0.488 1 0 WCM0_LM2 20 6022157 25284255 0.0632−0.2423 1.1355 0.5553 1 1 WCM0_LM2 20 25287535 34317470 −0.1843 −0.50320.9013 0.5098 1 1 WCM0_LM2 20 34319996 35646733 0.0576 −0.2482 NA NA NANA WCM0_LM2 20 35649104 35717534 −0.1287 −0.4443 NA NA NA NA WCM0_LM2 2035724166 45771777 0.3337 0.0403 1.0294 1.0272 1 1 WCM0_LM2 20 4579782155213077 0.1817 −0.1182 0.9291 0.9136 1 1 WCM0_LM2 20 55746069 620767430.4089 0.1185 1.0912 1.0799 1 1 WCM0_LM2 20 62078160 62680301 0.1698−0.1307 0.9229 0.9038 1 1 WCM0_LM2 20 62680599 62904890 0.4575 0.1689 NANA NA NA WCM0_LM2 21 10862618 34400082 0.3411 0.048 1.0403 1.0274 1 1WCM0_LM2 21 34442624 36081024 0.2171 −0.0812 0.961 0.9295 1 1 WCM0_LM221 36081626 37518362 −0.5467 −0.8901 NA NA NA NA WCM0_LM2 21 3751879137781756 0.0685 −0.2368 NA NA NA NA WCM0_LM2 21 37783854 48084277 0.36590.0738 1.0568 1.0481 1 1 WCM0_LM2 22 16255826 28310267 −0.6349 −0.98541.0136 −0.0034 1 0 WCM0_LM2 22 28315195 43575733 −0.7425 −1.1023 0.9428−0.0112 1 0 WCM0_LM2 22 43576012 51216382 −0.6547 −1.0068 0.9992 −0.00391 0 WCM0_LM2 3 361508 9426194 −0.5228 −0.8643 1.0983 3.00E−04 1 0WCM0_LM2 3 9470717 10360847 −0.7534 −1.1141 0.9258 −0.0019 1 0 WCM0_LM23 10362734 47088052 −0.5503 −0.894 1.0773 −0.0011 1 0 WCM0_LM2 347098357 50211269 −0.7599 −1.1212 0.9295 −0.0101 1 0 WCM0_LM2 3 5021164156600977 −0.5628 −0.9075 1.0677 −0.0014 1 0 WCM0_LM2 3 56605328 58355222−0.7496 −1.11 0.9339 −0.0073 1 0 WCM0_LM2 3 58368449 73437085 −0.5284−0.8705 1.0968 −0.0028 1 0 WCM0_LM2 3 73439038 73673935 −0.3539 −0.6835NA NA NA NA WCM0_LM2 3 74313609 75986686 0.9613 0.6884 NA NA NA NAWCM0_LM2 3 77089935 93780313 0.2263 −0.0716 NA NA NA NA WCM0_LM2 393782011 122103070 −0.5639 −0.9087 1.0668 −0.0015 1 0 WCM0_LM2 3122121686 122419305 0.2749 −0.0209 NA NA NA NA WCM0_LM2 3 122419676134968372 0.3893 0.0981 1.0748 1.0659 1 1 WCM0_LM2 3 134977941 1386694170.2068 −0.092 NA NA NA NA WCM0_LM2 3 138738875 141231057 0.5137 0.2271NA NA NA NA WCM0_LM2 3 141235302 142681100 0.1721 −0.1282 0.915 0.915 11 WCM0_LM2 3 142681387 169485905 0.3913 0.1002 1.0753 1.0686 1 1WCM0_LM2 3 169486144 186760820 0.2448 −0.0524 0.9674 0.9613 1 1 WCM0_LM23 186761066 194126811 0.4204 0.1304 1.1003 1.0889 1 1 WCM0_LM2 3194134535 197847254 0.1567 −0.1443 0.9133 0.8963 1 1 WCM0_LM2 4 534243213848 −0.2337 −0.5556 0.8299 0.5309 1 1 WCM0_LM2 4 3214350 38775142−0.0488 −0.3601 1.0032 0.555 1 1 WCM0_LM2 4 38775350 39201204 −0.2034−0.5234 0.855 0.5364 1 1 WCM0_LM2 4 39205259 40832484 −0.4446 −0.78050.7388 0.4256 1 0 WCM0_LM2 4 40892531 41035318 −1.6125 −2.0832 NA NA NANA WCM0_LM2 4 41259149 41362962 −0.2233 −0.5445 NA NA NA NA WCM0_LM2 441496568 44631587 −1.4169 −1.8557 0.544 0.0086 1 0 WCM0_LM2 4 4463804865147257 −0.066 −0.3782 1.0241 0.5147 1 1 WCM0_LM2 4 65155423 715035800.3344 0.041 1.0353 1.0224 1 1 WCM0_LM2 4 71507712 71895093 0.0571−0.2487 NA NA NA NA WCM0_LM2 4 72102288 73924001 −0.5136 −0.8545 NA NANA NA WCM0_LM2 4 73927521 106158303 0.3111 0.0168 1.0159 1.0075 1 1WCM0_LM2 4 106158545 106474000 −0.5826 −0.9288 NA NA NA NA WCM0_LM2 4106510551 174537763 0.3142 0.02 1.0224 1.0055 1 1 WCM0_LM2 4 175158641177084265 −0.0119 −0.3212 NA NA NA NA WCM0_LM2 4 177087286 178911657−0.695 −1.0506 NA NA NA NA WCM0_LM2 4 183090436 190947560 −0.098 −0.41190.988 0.5152 1 1 WCM0_LM2 5 140681 192214 0.1443 −0.1573 NA NA NA NAWCM0_LM2 5 192445 1495038 −0.0356 −0.3462 1.0327 0.5407 1 1 WCM0_LM2 51501550 16479110 0.0886 −0.2157 1.1428 0.5795 1 1 WCM0_LM2 5 1648118588416361 −0.0686 −0.381 1.0108 0.525 1 1 WCM0_LM2 5 89689893 1229500420.3547 0.0622 1.0516 1.0364 1 1 WCM0_LM2 5 123966403 123983184 −0.34−0.6687 NA NA NA NA WCM0_LM2 5 123983401 126171922 −0.7772 −1.1401 NA NANA NA WCM0_LM2 5 126206303 132198287 −0.5375 −0.8802 1.0873 −7.00E−04  10 WCM0_LM2 5 132199874 134369377 −0.7657 −1.1275 0.9161 −7.00E−04  1 0WCM0_LM2 5 134670765 136957765 −0.3381 −0.6666 1.2305 0.0295 1 0WCM0_LM2 5 136961471 137661766 0.0899 −0.2143 NA NA NA NA WCM0_LM2 5137664235 140174634 0.1865 −0.1132 0.9361 0.9129 1 1 WCM0_LM2 5140174822 170323125 0.341 0.0479 1.0381 1.0295 1 1 WCM0_LM2 5 170336668180687812 0.2071 −0.0916 0.9443 0.9326 1 1 WCM0_LM2 6 292598 386505880.2967 0.0017 1.0043 0.9981 1 1 WCM0_LM2 6 38652308 41318641 0.47630.1884 1.1655 1.1135 1 1 WCM0_LM2 6 41533685 43639680 0.2066 −0.09220.939 0.9371 1 1 WCM0_LM2 6 43642929 56765338 0.4379 0.1485 1.11651.1004 1 1 WCM0_LM2 6 56818622 91296463 0.2867 −0.0086 1.0614 0.9267 1 1WCM0_LM2 6 93953242 97730322 0.0422 −0.2643 NA NA NA NA WCM0_LM2 699282794 118972442 0.36 0.0677 1.0611 1.0349 1 1 WCM0_LM2 6 119222019121768849 −0.0502 −0.3615 NA NA NA NA WCM0_LM2 6 122720983 1249795100.4086 0.1182 NA NA NA NA WCM0_LM2 6 125112467 149395270 −0.0055 −0.31451.0824 0.5259 1 1 WCM0_LM2 6 149691155 151939210 −0.1888 −0.5079 0.96840.4381 1 0 WCM0_LM2 6 152129246 166755979 −0.0401 −0.3509 1.0368 0.53141 1 WCM0_LM2 6 166778877 170893364 0.4645 0.1762 1.1592 1.1006 1 1WCM0_LM2 7 193578 4900132 0.2325 −0.0652 0.9648 0.9468 1 1 WCM0_LM2 74900442 7118626 0.0181 −0.2897 0.8387 0.7974 1 1 WCM0_LM2 7 727409422771138 0.4337 0.1442 1.1109 1.0994 1 1 WCM0_LM2 7 22852843 271960680.282 −0.0136 1.0133 0.9679 1 1 WCM0_LM2 7 27203339 27689282 −0.5128−0.8536 NA NA NA NA WCM0_LM2 7 27702390 29160564 0.4545 0.1658 NA NA NANA WCM0_LM2 7 29394264 38398377 −0.482 −0.8205 1.1352 −0.0028 1 0WCM0_LM2 7 38402486 55565332 0.3784 0.0868 1.073 1.0509 1 1 WCM0_LM2 755588756 77755197 0.0987 −0.205 0.8748 0.8602 1 1 WCM0_LM2 7 7775664997364091 0.4001 0.1094 1.081 1.0765 1 1 WCM0_LM2 7 97365643 1025723010.0895 −0.2148 0.9764 0.747 1 1 WCM0_LM2 7 102574422 107688446 0.2526−0.0442 0.98 0.9597 1 1 WCM0_LM2 7 107688571 127847987 0.4056 0.11511.0931 1.0729 1 1 WCM0_LM2 7 127892030 137600663 0.2861 −0.0093 0.99880.9884 1 1 WCM0_LM2 7 137613080 140710306 0.151 −0.1504 0.9039 0.8982 11 WCM0_LM2 7 141255364 158937481 0.3637 0.0714 1.0573 1.0442 1 1WCM0_LM2 8 192902 2092907 −4.0684 −6.8052 NA NA NA NA WCM0_LM2 8 279624336703425 −0.4687 −0.8062 1.1486 −0.0049 1 0 WCM0_LM2 8 36722007 376864080.4284 0.1387 NA NA NA NA WCM0_LM2 8 37686742 49641670 0.2568 −0.03980.9951 0.9505 1 1 WCM0_LM2 8 49642417 67372731 0.4412 0.152 1.12611.0961 1 1 WCM0_LM2 8 67380528 68423840 0.1469 −0.1546 NA NA NA NAWCM0_LM2 8 68430319 105601105 0.4061 0.1155 1.0901 1.0766 1 1 WCM0_LM2 8106430834 131249154 −0.4665 −0.8039 1.1491 −0.0036 1 0 WCM0_LM2 8131370259 140715014 −0.3087 −0.6353 1.2758 0.0118 1 0 WCM0_LM2 8140715222 146279476 −0.5106 −0.8512 1.1133 −0.0047 1 0 WCM0_LM2 9 1176663395520 −1.4882 −1.938 0.5264 −0.0044 1 0 WCM0_LM2 9 3828232 190329070.0174 −0.2904 1.1115 0.5238 1 1 WCM0_LM2 9 19049792 40772506 −0.5509−0.8947 1.0879 −0.0121 1 0 WCM0_LM2 9 40773337 99416976 −0.0973 −0.41121.0663 0.4377 1 0 WCM0_LM2 9 99521023 114090390 0.3523 0.0596 1.04761.0368 1 1 WCM0_LM2 9 114090601 116122975 0.1592 −0.1418 0.9216 0.8912 11 WCM0_LM2 9 116124604 116303584 0.3053 0.0107 NA NA NA NA WCM0_LM2 9116345746 123230157 0.4729 0.1848 1.1426 1.1308 1 1 WCM0_LM2 9 123232405127300561 0.3197 0.0257 1.0254 1.0105 1 1 WCM0_LM2 9 127302394 1357024480.1742 −0.1261 0.9192 0.9134 1 1 WCM0_LM2 9 135703440 141071438 0.32320.0294 1.0238 1.0174 1 1 WCM0_LM2 X 2700140 5950784 0.2095 −0.0892 NA NANA NA WCM0_LM2 X 6069121 15527472 0.4174 0.1273 NA NA NA NA WCM0_LM2 X15529580 100662726 0.2467 −0.0504 NA NA NA NA WCM0_LM2 X 100808315112034033 0.442 0.1528 NA NA NA NA WCM0_LM2 X 112035075 125299467 0.1779−0.1222 NA NA NA NA WCM0_LM2 X 125299645 154509348 0.8717 0.5963 NA NANA NA WCM0_PM1 1 808999 2560735 0.1589 −0.1421 0.9109 0.9015 1 1WCM0_PM1 1 2938320 6219610 0.3758 0.084 1.0732 1.0468 1 1 WCM0_PM1 16228265 11986004 0.1131 −0.19 0.8812 0.872 1 1 WCM0_PM1 1 1199491017950850 −0.7599 −1.1212 0.921 −0.0016 1 0 WCM0_PM1 1 17952432 19448407−0.4833 −0.822 1.1311 2.00E−04 1 0 WCM0_PM1 1 19449351 19609254 −0.7176−1.0751 0.959 −0.0097 1 0 WCM0_PM1 1 19611241 27755381 −0.0152 −0.32470.9144 0.6825 1 1 WCM0_PM1 1 27874007 27878413 1.7295 1.4718 NA NA NA NAWCM0_PM1 1 27939619 32280238 0.7136 0.4337 1.7252 0.9761 2 1 WCM0_PM1 132280311 33557797 0.4236 0.1337 1.4308 0.7634 1 1 WCM0_PM1 1 3355893833613329 0.6532 0.3714 NA NA NA NA WCM0_PM1 1 33623966 35370875 0.93750.664 NA NA NA NA WCM0_PM1 1 35452804 41013005 0.5352 0.2494 1.44830.9291 1 1 WCM0_PM1 1 41092196 45205685 0.6929 0.4123 1.5518 1.1099 2 1WCM0_PM1 1 45206676 45243625 0.6085 0.3252 NA NA NA NA WCM0_PM1 145243741 51778500 0.503 0.216 1.3492 0.9738 1 1 WCM0_PM1 1 5178749653516315 0.27 −0.026 NA NA NA NA WCM0_PM1 1 53527948 61872414 0.57340.2889 1.3759 1.0676 1 1 WCM0_PM1 1 61920994 64011682 0.2325 −0.06520.9957 0.9159 1 1 WCM0_PM1 1 64017382 90486493 0.5182 0.2318 1.19621.1524 1 1 WCM0_PM1 1 90487798 91182716 0.8044 0.5272 NA NA NA NAWCM0_PM1 1 91382423 94018018 −0.712 −1.0691 0.9524 8.00E−04 1 0 WCM0_PM11 94027772 109171074 −0.4489 −0.785 1.1563 0.0044 1 0 WCM0_PM1 1109171370 109271473 −0.6294 −0.9795 NA NA NA NA WCM0_PM1 1 109273311109964463 −0.7224 −1.0803 0.9433 0.0026 1 0 WCM0_PM1 1 109968935112991698 −0.4264 −0.761 1.1701 0.0101 1 0 WCM0_PM1 1 112991790115576719 −0.6305 −0.9807 1.0053 0.0082 1 0 WCM0_PM1 1 115576823119935289 −0.4003 −0.733 1.2038 −5.00E−04  1 0 WCM0_PM1 1 119936435145115810 −0.2783 −0.6029 1.0617 0.2552 1 0 WCM0_PM1 1 145139406149921981 −0.1009 −0.415 1.031 0.469 1 0 WCM0_PM1 1 149931698 152079989−0.3517 −0.6811 0.7867 0.4607 1 0 WCM0_PM1 1 152080243 153391752 0.0359−0.271 0.9532 0.7043 1 1 WCM0_PM1 1 153409657 153580668 −0.331 −0.659 NANA NA NA WCM0_PM1 1 153587435 155173361 −0.4962 −0.8358 0.6572 0.4634 10 WCM0_PM1 1 155174667 156339241 −0.6111 −0.9597 0.6498 0.3786 1 0WCM0_PM1 1 156347289 156873714 −0.396 −0.7284 0.703 0.5042 1 1 WCM0_PM11 156874512 160786624 −0.0932 −0.4069 0.8872 0.6213 1 1 WCM0_PM1 1160788089 161487989 −0.463 −0.8002 NA NA NA NA WCM0_PM1 1 161494909173490418 −0.1465 −0.4631 0.8512 0.5996 1 1 WCM0_PM1 1 173493205174976273 −0.3572 −0.6869 NA NA NA NA WCM0_PM1 1 174977786 178745891−0.0081 −0.3172 0.9546 0.6506 1 1 WCM0_PM1 1 178753657 180144472 −0.4173−0.7512 0.6431 0.5451 1 1 WCM0_PM1 1 180145155 180832953 −0.1711 −0.4892NA NA NA NA WCM0_PM1 1 180842940 198828281 0.118 −0.1849 1.1755 0.584 11 WCM0_PM1 1 199997023 205890946 −0.057 −0.3687 1.0307 0.5182 1 1WCM0_PM1 1 205892303 211263914 0.1704 −0.1301 1.188 0.6396 1 1 WCM0_PM11 211276849 213445936 −0.1157 −0.4306 0.9574 0.5265 1 1 WCM0_PM1 1214169997 223986386 0.1257 −0.1768 1.183 0.5864 1 1 WCM0_PM1 1 223987701226567838 −0.1787 −0.4973 0.911 0.5059 1 1 WCM0_PM1 1 226568860233231604 0.2365 −0.061 0.9756 0.9416 1 1 WCM0_PM1 1 233270956 233394314−0.6191 −0.9683 NA NA NA NA WCM0_PM1 1 233394739 234745243 0.2638−0.0326 1.0042 0.9512 1 1 WCM0_PM1 1 235277191 236767444 −0.049 −0.36030.7922 0.7659 1 1 WCM0_PM1 1 236849945 240256822 0.2715 −0.0245 1.02820.9381 1 1 WCM0_PM1 1 240256995 247492594 0.1094 −0.1939 0.8907 0.8577 11 WCM0_PM1 1 247492845 249212577 0.4072 0.1167 1.1833 0.9852 1 1WCM0_PM1 10 226030 5454638 −0.4128 −0.7464 1.1822 0.01 1 0 WCM0_PM1 105468674 44868750 −0.6676 −1.0208 0.9846 0.0011 1 0 WCM0_PM1 10 4487141564911893 −0.4201 −0.7542 1.1811 0.0047 1 0 WCM0_PM1 10 64927891 65928961−0.8733 −1.2453 NA NA NA NA WCM0_PM1 10 65929410 71078775 −0.9366 −1.3150.8087 −0.0048 1 0 WCM0_PM1 10 71103597 73767859 −0.5316 −0.8739 1.08250.0088 1 0 WCM0_PM1 10 73768169 76989406 −0.7844 −1.1479 0.9088 −0.00621 0 WCM0_PM1 10 76993786 92982637 −0.4679 −0.8055 1.1431 0.0013 1 0WCM0_PM1 10 93000258 99527563 −0.6746 −1.0284 0.9833 −0.0028 1 0WCM0_PM1 10 99529499 101478074 −0.4314 −0.7663 1.1558 0.02 1 0 WCM0_PM110 101478296 105765735 −0.7684 −1.1305 0.9203 −0.0068 1 0 WCM0_PM1 10105768114 120354668 −0.4948 −0.8342 1.1092 0.0126 1 0 WCM0_PM1 10120445630 121678041 −0.7449 −1.1048 NA NA NA NA WCM0_PM1 10 121679118135373653 −0.4742 −0.8121 1.1374 0.0017 1 0 WCM0_PM1 11 193096 1958179−0.7117 −1.0687 0.9428 0.0107 1 0 WCM0_PM1 11 1959656 4389433 −0.5249−0.8667 1.0895 0.0073 1 0 WCM0_PM1 11 4406533 8118414 −0.2863 −0.61151.295 0.014 1 0 WCM0_PM1 11 8118740 8950950 −0.4816 −0.8201 NA NA NA NAWCM0_PM1 11 8953687 10215506 −0.7355 −1.0946 0.9415 −0.005 1 0 WCM0_PM111 10327290 18048219 −0.3754 −0.7064 1.2196 0.0061 1 0 WCM0_PM1 1118050907 18722791 −0.6415 −0.9925 1.0305 −0.0253 1 0 WCM0_PM1 1118723243 32605410 −0.3446 −0.6735 1.2408 0.0132 1 0 WCM0_PM1 11 3260848734533145 −0.6805 −1.0348 0.9717 0.0044 1 0 WCM0_PM1 11 34664274 45967621−0.3727 −0.7036 1.2199 0.0082 1 0 WCM0_PM1 11 45970395 48632382 −0.8284−1.196 0.8706 0.0023 1 0 WCM0_PM1 11 49059138 61049400 −0.4925 −0.83191.111 0.0126 1 0 WCM0_PM1 11 61050414 69488012 −0.7674 −1.1294 0.921−0.0068 1 0 WCM0_PM1 11 69489942 78279790 0.3203 0.0263 1.0237 1.0131 11 WCM0_PM1 11 78282405 107288907 0.4611 0.1726 1.1282 1.1259 1 1WCM0_PM1 11 107299631 108412378 0.1469 −0.1546 0.8984 0.8984 1 1WCM0_PM1 11 108464103 116798133 0.4092 0.1188 1.1027 1.0689 1 1 WCM0_PM111 116824796 117117528 −0.7115 −1.0685 NA NA NA NA WCM0_PM1 11 117150646118656889 0.1888 −0.1108 0.9677 0.8844 1 1 WCM0_PM1 11 118754631119005066 −0.807 −1.1726 NA NA NA NA WCM0_PM1 11 119020704 1191806160.2753 −0.0205 NA NA NA NA WCM0_PM1 11 119181170 134257494 0.4804 0.19261.1464 1.1393 1 1 WCM0_PM1 12 247582 6219763 −0.5051 −0.8453 1.11248.00E−04 1 0 WCM0_PM1 12 6220067 9070366 −0.7476 −1.1078 0.9282−2.00E−04  1 0 WCM0_PM1 12 9072399 9459772 −0.5273 −0.8692 NA NA NA NAWCM0_PM1 12 9464146 9723417 0.2518 −0.045 NA NA NA NA WCM0_PM1 129747833 25348041 −0.4949 −0.8343 1.1025 0.0192 1 0 WCM0_PM1 12 2535695331285255 0.3909 0.0998 1.0927 1.0504 1 1 WCM0_PM1 12 31288604 329754530.0615 −0.2441 0.8718 0.8169 1 1 WCM0_PM1 12 32976987 41587946 0.39920.1084 NA NA NA NA WCM0_PM1 12 41831837 42840394 −0.6211 −0.9704 NA NANA NA WCM0_PM1 12 42853638 48741912 −0.45 −0.7862 1.1417 0.018 1 0WCM0_PM1 12 48743865 52200100 −0.8023 −1.1675 0.8965 −0.0061 1 0WCM0_PM1 12 52200459 53295827 −0.4489 −0.785 1.152 0.0087 1 0 WCM0_PM112 53298468 54070021 −0.8524 −1.2224 0.864 −0.0069 1 0 WCM0_PM1 1254105819 56142337 −0.5704 −0.9157 NA NA NA NA WCM0_PM1 12 5614266257110231 −0.8764 −1.2487 NA NA NA NA WCM0_PM1 12 57110604 57995392 −0.67−1.0234 0.9914 −0.0075 1 0 WCM0_PM1 12 58000350 77260012 −0.5494 −0.8931.0705 0.0065 1 0 WCM0_PM1 12 77417806 93169949 −0.4116 −0.7451 1.18840.0049 1 0 WCM0_PM1 12 93170703 94676118 −0.62 −0.9692 NA NA NA NAWCM0_PM1 12 94688232 102224465 −0.6893 −1.0444 0.9782 −0.0085 1 0WCM0_PM1 12 102271729 108919881 −0.4974 −0.837 1.1179 0.0016 1 0WCM0_PM1 12 108920216 110403609 −0.7161 −1.0735 0.9533 −0.0029 1 0WCM0_PM1 12 110405149 112926987 −0.916 −1.2923 NA NA NA NA WCM0_PM1 12112942618 120536922 −0.6441 −0.9954 1.0063 −0.0031 1 0 WCM0_PM1 12120541618 124175252 −0.9175 −1.294 0.829 −0.0133 1 0 WCM0_PM1 12124177196 133779197 −0.6301 −0.9801 1.0155 −0.0016 1 0 WCM0_PM1 1319705470 19969223 −0.4687 −0.8062 NA NA NA NA WCM0_PM1 13 1997202923915758 −0.8061 −1.1716 0.8839 0.004 1 0 WCM0_PM1 13 23927969 80911785−0.5224 −0.8639 1.0921 0.0068 1 0 WCM0_PM1 13 84453738 95686877 0.56580.281 NA NA NA NA WCM0_PM1 13 95695990 101287231 0.3267 0.033 2.0517−0.0055 2 0 WCM0_PM1 13 101287365 113158944 0.5459 0.2604 2.3878 0.00792 0 WCM0_PM1 13 113170707 114498140 0.3542 0.0616 2.0812 0.0061 2 0WCM0_PM1 13 114502382 115089411 0.6008 0.3173 2.4744 0.0176 2 0 WCM0_PM114 19553749 20692044 0.4177 0.1276 1.1015 1.0834 1 1 WCM0_PM1 1420692188 22134203 0.2126 −0.086 0.9451 0.9392 1 1 WCM0_PM1 14 2216728223236528 0.4945 0.2073 1.1772 1.1318 1 1 WCM0_PM1 14 23237175 237913680.104 −0.1996 0.9219 0.8197 1 1 WCM0_PM1 14 23792215 31598638 0.38180.0904 1.0713 1.058 1 1 WCM0_PM1 14 31602596 34420005 0.0394 −0.2673 NANA NA NA WCM0_PM1 14 34904445 36231940 −0.4437 −0.7795 NA NA NA NAWCM0_PM1 14 36240179 47600987 −0.0726 −0.3851 1.0305 0.5009 1 1 WCM0_PM114 50044532 50971559 −0.3225 −0.65 NA NA NA NA WCM0_PM1 14 5099866463784574 −0.0867 −0.4 1.0033 0.5124 1 1 WCM0_PM1 14 63842768 65007733−0.3112 −0.638 NA NA NA NA WCM0_PM1 14 65007871 73441696 −0.0684 −0.38071.0255 0.5106 1 1 WCM0_PM1 14 73442442 75748069 −0.3397 −0.6684 0.82650.432 1 0 WCM0_PM1 14 75904650 77242347 −0.0572 −0.3689 NA NA NA NAWCM0_PM1 14 77242535 78365565 −0.2781 −0.6027 0.8735 0.4436 1 0 WCM0_PM114 78374254 86089315 0.0558 −0.2501 NA NA NA NA WCM0_PM1 14 8608935789082517 0.367 0.0749 NA NA NA NA WCM0_PM1 14 89083185 93995606 0.1988−0.1004 0.9376 0.9279 1 1 WCM0_PM1 14 93998888 95267286 0.4585 0.16991.153 1.097 1 1 WCM0_PM1 14 95556812 95657985 −0.602 −0.9498 NA NA NA NAWCM0_PM1 14 95660135 102252462 0.3844 0.093 1.0976 1.0356 1 1 WCM0_PM114 102276301 104493246 0.0865 −0.2179 0.8652 0.8544 1 1 WCM0_PM1 14104508456 107283105 0.2737 −0.0222 0.9981 0.9714 1 1 WCM0_PM1 1520170117 40708277 −0.0435 −0.3545 1.0317 0.5325 1 1 WCM0_PM1 15 4070854642059256 −0.4091 −0.7424 NA NA NA NA WCM0_PM1 15 42067548 43893123−0.1926 −0.512 0.9264 0.4762 1 0 WCM0_PM1 15 43893585 45206957 −0.334−0.6622 NA NA NA NA WCM0_PM1 15 45220859 50339649 0.0257 −0.2816 1.08890.5564 1 1 WCM0_PM1 15 50366356 64275947 −0.1428 −0.4593 0.968 0.4866 10 WCM0_PM1 15 64332459 66850133 −0.3277 −0.6555 NA NA NA NA WCM0_PM1 1566850321 74574137 −0.0734 −0.3859 1.0066 0.524 1 1 WCM0_PM1 15 7458826176426561 −0.2698 −0.5939 0.8477 0.4773 1 0 WCM0_PM1 15 76430111 90208910−0.0923 −0.4059 0.9682 0.5413 1 1 WCM0_PM1 15 90209135 91358441 −0.3631−0.6933 0.8277 0.4092 1 0 WCM0_PM1 15 91419099 93555670 −0.1765 −0.49490.9357 0.4835 1 0 WCM0_PM1 15 93557907 102359175 0.0561 −0.2498 1.09440.5877 1 1 WCM0_PM1 16 79642 780924 −0.7116 −1.0685 0.9522 0.0014 1 0WCM0_PM1 16 781633 19800223 −0.7938 −1.1582 0.8986 −0.0025 1 0 WCM0_PM116 19838334 20800886 −0.5086 −0.8491 NA NA NA NA WCM0_PM1 16 2080198228145156 −0.7785 −1.1415 0.9082 −0.0016 1 0 WCM0_PM1 16 2814663231049751 −0.9077 −1.2831 0.8304 −0.0086 1 0 WCM0_PM1 16 3105001831155204 −0.8114 −1.1775 NA NA NA NA WCM0_PM1 16 31157126 47409798−0.7085 −1.0652 0.944 0.0118 1 0 WCM0_PM1 16 47462746 56717096 −0.5407−0.8837 1.0819 0.0021 1 0 WCM0_PM1 16 56717863 66670382 −0.6982 −1.0540.961 0.0023 1 0 WCM0_PM1 16 66730217 70694103 −0.8229 −1.19 0.8842−0.0076 1 0 WCM0_PM1 16 70697774 90162264 −0.6529 −1.0049 1.0005 −0.00391 0 WCM0_PM1 17 131595 531406 0.2289 −0.0689 NA NA NA NA WCM0_PM1 17534752 5341450 0.0645 −0.2409 0.8462 0.8462 1 1 WCM0_PM1 17 53476887579892 0.2148 −0.0836 0.9437 0.9437 1 1 WCM0_PM1 17 7592111 7951897−0.7604 −1.1217 NA NA NA NA WCM0_PM1 17 7976288 10427223 0.1769 −0.12320.9316 0.9047 1 1 WCM0_PM1 17 10427923 15406427 0.3449 0.052 1.04531.028 1 1 WCM0_PM1 17 15449153 28030047 0.1965 −0.1027 0.9955 0.867 1 1WCM0_PM1 17 28120931 28773006 0.7289 0.4494 NA NA NA NA WCM0_PM1 1728776594 31065347 −0.8137 −1.18 0.8925 −0.0098 1 0 WCM0_PM1 17 3107224535307467 −0.5318 −0.874 1.0871 0.0041 1 0 WCM0_PM1 17 35307729 38636045−0.7797 −1.1428 0.9143 −0.0085 1 0 WCM0_PM1 17 38636989 39728203 −0.4739−0.8118 1.1296 0.0097 1 0 WCM0_PM1 17 39728249 47921402 −0.7834 −1.14690.9103 −0.0071 1 0 WCM0_PM1 17 47925346 56604517 −0.5811 −0.9272 1.05143.00E−04 1 0 WCM0_PM1 17 56606456 59853725 −0.8205 −1.1874 0.8886−0.0104 1 0 WCM0_PM1 17 59857621 66526549 0.1099 −0.1933 0.8883 0.8608 11 WCM0_PM1 17 66533655 70645373 0.3339 0.0405 1.0724 0.9846 1 1 WCM0_PM117 70732816 72877302 0.1367 −0.1653 0.9776 0.8059 1 1 WCM0_PM1 1772878633 75303202 0.0197 −0.288 0.8776 0.7605 1 1 WCM0_PM1 17 7531638381052243 0.163 −0.1378 0.9821 0.8357 1 1 WCM0_PM1 18 47646 146135720.8425 0.5664 1.939 1.0225 2 1 WCM0_PM1 18 18539811 22030809 −0.7553−1.1161 0.9221 6.00E−04 1 0 WCM0_PM1 18 22040802 74980855 −0.4754−0.8134 1.1248 0.0133 1 0 WCM0_PM1 18 76753131 77287526 0.8945 0.6198 NANA NA NA WCM0_PM1 18 77440041 78005274 −0.3486 −0.6778 NA NA NA NAWCM0_PM1 19 281360 6374940 0.0073 −0.301 0.8194 0.804 1 1 WCM0_PM1 196375471 15079170 0.3452 0.0522 1.2785 0.7953 1 1 WCM0_PM1 19 1508253716296543 0.5368 0.2511 1.466 0.9142 1 1 WCM0_PM1 19 16301349 194665040.3453 0.0524 1.2732 0.8007 1 1 WCM0_PM1 19 19478892 36128173 0.50810.2213 1.4411 0.8905 1 1 WCM0_PM1 19 36128439 39688815 0.3431 0.05011.2679 0.8027 1 1 WCM0_PM1 19 39689893 42597927 0.515 0.2284 1.42630.9168 1 1 WCM0_PM1 19 42599631 42730600 −0.0329 −0.3433 NA NA NA NAWCM0_PM1 19 42736292 42848999 −4.2504 −8.4086 NA NA NA NA WCM0_PM1 1942853720 44160711 −0.062 −0.374 1.5451 −0.0018 2 0 WCM0_PM1 19 4416965045211467 0.5585 0.2735 1.4726 0.9449 1 1 WCM0_PM1 19 45213783 486431950.3691 0.0771 1.2764 0.8334 1 1 WCM0_PM1 19 48646883 51171634 0.057−0.2488 0.8531 0.8301 1 1 WCM0_PM1 19 51171919 52543806 0.2801 −0.01551.0079 0.9707 1 1 WCM0_PM1 19 52544833 56569596 0.1139 −0.1891 0.95340.8009 1 1 WCM0_PM1 19 56572935 58721339 0.3735 0.0816 1.2078 0.9086 1 1WCM0_PM1 19 58723103 59082767 0.0723 −0.2327 0.9662 0.7359 1 1 WCM0_PM12 41613 9541373 0.3347 0.0413 1.0451 1.013 1 1 WCM0_PM1 2 954346321266425 −0.035 −0.3456 0.9188 0.6552 1 1 WCM0_PM1 2 23974938 29165168−0.4151 −0.7488 0.697 0.4932 1 0 WCM0_PM1 2 29169313 31805928 −0.0654−0.3775 0.9101 0.6294 1 1 WCM0_PM1 2 32093528 32897357 −0.5985 −0.946 NANA NA NA WCM0_PM1 2 32903985 39250247 −0.3047 −0.631 0.7578 0.5337 1 1WCM0_PM1 2 39251221 44934480 −0.0646 −0.3767 0.801 0.7393 1 1 WCM0_PM1 244942462 60983595 0.1813 −0.1186 1.0289 0.8132 1 1 WCM0_PM1 2 6098743562728379 −0.1646 −0.4823 0.7666 0.6651 1 1 WCM0_PM1 2 62728589 682744710.1672 −0.1334 0.9841 0.8392 1 1 WCM0_PM1 2 68352543 69784085 0.45580.1672 1.1485 1.0972 1 1 WCM0_PM1 2 69870158 72802770 −0.5466 −0.891.0791 2.00E−04 1 0 WCM0_PM1 2 72945383 74867316 −0.7502 −1.1106 0.9250.0012 1 0 WCM0_PM1 2 74867419 85133176 −0.5233 −0.8649 1.0861 0.0121 10 WCM0_PM1 2 85133552 86733121 −0.9407 −1.3195 0.8076 −0.0063 1 0WCM0_PM1 2 86734630 91955271 −0.689 −1.0441 0.9389 0.031 1 0 WCM0_PM1 291955350 109068837 0.3 0.0052 1.0214 0.9858 1 1 WCM0_PM1 2 109085449113959031 0.1251 −0.1774 0.9149 0.8537 1 1 WCM0_PM1 2 113976089116101462 −0.6291 −0.9791 NA NA NA NA WCM0_PM1 2 116257074 1165399550.1741 −0.1261 NA NA NA NA WCM0_PM1 2 116548650 120690074 0.391 0.09981.0984 1.0449 1 1 WCM0_PM1 2 120692493 149501213 −0.6371 −0.9878 1.0060.0026 1 0 WCM0_PM1 2 149511523 153192188 0.2848 −0.0106 1.003 0.9823 11 WCM0_PM1 2 153378459 170218914 0.4536 0.1648 1.1292 1.1129 1 1WCM0_PM1 2 170336047 175613600 0.2469 −0.0501 0.9951 0.9366 1 1 WCM0_PM12 175614684 179314930 0.4339 0.1444 1.1271 1.0835 1 1 WCM0_PM1 2179315781 182786948 0.5337 0.2479 1.2034 1.1715 1 1 WCM0_PM1 2 182794384197595567 0.4106 0.1202 1.1004 1.0734 1 1 WCM0_PM1 2 197596876 2016780110.3242 0.0304 1.0415 1.0011 1 1 WCM0_PM1 2 201680222 204571465 0.1152−0.1878 0.9028 0.8531 1 1 WCM0_PM1 2 204591428 219029182 0.3848 0.09351.0836 1.0503 1 1 WCM0_PM1 2 219029682 220252494 0.2059 −0.093 0.94840.9268 1 1 WCM0_PM1 2 220283189 223918019 0.3676 0.0755 1.0746 1.0329 11 WCM0_PM1 2 224462339 232458726 0.1181 −0.1847 0.9001 0.8595 1 1WCM0_PM1 2 232573388 234344561 −0.7354 −1.0945 0.9472 −0.0106 1 0WCM0_PM1 2 234345100 234621787 0.2214 −0.0768 0.9799 0.9165 1 1 WCM0_PM12 234622061 234656640 0.4466 0.1576 NA NA NA NA WCM0_PM1 2 234669127242003080 0.4242 0.1343 1.1056 1.0896 1 1 WCM0_PM1 2 242003502 2428154620.2467 −0.0504 0.9868 0.9445 1 1 WCM0_PM1 20 68342 2398091 0.455 0.16631.128 1.1164 1 1 WCM0_PM1 20 2398184 6011999 0.2195 −0.0787 0.96170.9321 1 1 WCM0_PM1 20 6012706 26188920 0.4887 0.2013 1.1664 1.133 1 1WCM0_PM1 20 29845457 36012697 0.1078 −0.1955 0.8769 0.8696 1 1 WCM0_PM120 36012825 45808514 0.3345 0.0412 1.0375 1.0204 1 1 WCM0_PM1 2045809420 50803444 0.1156 −0.1874 0.8782 0.8782 1 1 WCM0_PM1 20 5080363155748259 0.3117 0.0174 NA NA NA NA WCM0_PM1 20 55750037 60573214 0.49660.2094 1.167 1.1455 1 1 WCM0_PM1 20 60574216 62076164 0.312 0.0177 1.0250.9997 1 1 WCM0_PM1 20 62076743 62642800 0.158 −0.143 0.9094 0.9018 1 1WCM0_PM1 20 62648208 62904890 0.4196 0.1296 NA NA NA NA WCM0_PM1 2110862618 14917181 −0.0493 −0.3606 0.8962 0.6615 1 1 WCM0_PM1 21 1539986432513395 0.4737 0.1856 1.1385 1.1361 1 1 WCM0_PM1 21 32513843 361642920.2352 −0.0624 0.9807 0.9347 1 1 WCM0_PM1 21 36164704 37507720 −0.6577−1.0101 NA NA NA NA WCM0_PM1 21 37510210 38538354 0.1866 −0.1131 0.96320.8859 1 1 WCM0_PM1 21 38538782 44119121 0.4727 0.1847 1.146 1.1271 1 1WCM0_PM1 21 44152088 45846593 0.2926 −0.0025 1.044 0.9525 1 1 WCM0_PM121 45846961 48084270 0.498 0.2109 1.1646 1.1502 1 1 WCM0_PM1 22 1625582629095876 −0.6626 −1.0153 0.9882 0.0012 1 0 WCM0_PM1 22 29099475 32546363−0.7859 −1.1495 0.9048 −0.0033 1 0 WCM0_PM1 22 32546978 37904675 −0.6525−1.0044 0.9933 0.0037 1 0 WCM0_PM1 22 37906205 43435812 −0.8534 −1.22350.87 −0.0135 1 0 WCM0_PM1 22 43435962 51216446 −0.6654 −1.0184 0.98620.0012 1 0 WCM0_PM1 3 361508 9290644 −0.391 −0.7231 1.2021 0.0095 1 0WCM0_PM1 3 9406871 10261375 −0.7796 −1.1427 0.9252 −0.0194 1 0 WCM0_PM13 10264480 32169695 −0.5063 −0.8466 1.106 0.0062 1 0 WCM0_PM1 3 3218005333759443 −0.7379 −1.0972 NA NA NA NA WCM0_PM1 3 33840335 47044753−0.4706 −0.8084 1.1329 0.0092 1 0 WCM0_PM1 3 47045450 50405087 −0.8101−1.1761 0.8977 −0.0126 1 0 WCM0_PM1 3 50405270 53535717 −0.6142 −0.9631.0332 −0.0073 1 0 WCM0_PM1 3 53684957 56468391 −0.381 −0.7124 1.21270.0079 1 0 WCM0_PM1 3 56468819 58620019 −0.7522 −1.1128 0.9216 0.0032 10 WCM0_PM1 3 58622041 69058783 −0.3751 −0.706 1.2042 0.0218 1 0 WCM0_PM13 69072402 73657790 −0.5822 −0.9284 1.033 0.0179 1 0 WCM0_PM1 3 7367338177526717 0.8436 0.5675 NA NA NA NA WCM0_PM1 3 77530270 93768205 0.2263−0.0716 NA NA NA NA WCM0_PM1 3 93769707 122103160 −0.5075 −0.8479 1.09910.0121 1 0 WCM0_PM1 3 122121627 122598192 0.275 −0.0208 1.0083 0.9631 11 WCM0_PM1 3 122629084 124377324 0.506 0.2192 1.2171 1.111 1 1 WCM0_PM13 124378199 125702134 0.2866 −0.0088 1.0374 0.9504 1 1 WCM0_PM1 3125725378 128205826 0.5577 0.2726 1.2642 1.1518 1 1 WCM0_PM1 3 128292324129280522 0.1919 −0.1076 0.9281 0.9281 1 1 WCM0_PM1 3 129280739134968204 0.4445 0.1554 1.1276 1.0999 1 1 WCM0_PM1 3 134977937 1384781360.1868 −0.1128 NA NA NA NA WCM0_PM1 3 138664453 141164727 0.5277 0.2416NA NA NA NA WCM0_PM1 3 141206018 142607722 0.1675 −0.1331 0.9424 0.88141 1 WCM0_PM1 3 142681100 169492339 0.431 0.1414 1.1076 1.0984 1 1WCM0_PM1 3 169496714 170185108 0.1134 −0.1896 0.8998 0.8539 1 1 WCM0_PM13 170198275 182563242 0.313 0.0188 1.0363 0.9899 1 1 WCM0_PM1 3182566325 186760943 0.1432 −0.1585 0.9063 0.8856 1 1 WCM0_PM1 3186761066 193364861 0.4833 0.1956 1.1701 1.1203 1 1 WCM0_PM1 3 193365903197847274 0.1372 −0.1648 0.9005 0.8837 1 1 WCM0_PM1 4 53435 3237933 0.19−0.1096 0.9385 0.9152 1 1 WCM0_PM1 4 3240113 25032243 0.4002 0.10951.0788 1.0788 1 1 WCM0_PM1 4 25125641 38995588 0.2371 −0.0604 0.9610.957 1 1 WCM0_PM1 4 39000305 41270001 −0.0604 −0.3723 0.7799 0.7652 1 1WCM0_PM1 4 41362912 44631587 −0.5803 −0.9264 1.0503 0.0021 1 0 WCM0_PM14 44637961 56304722 0.3709 0.079 1.087 1.0255 1 1 WCM0_PM1 4 5630864057906986 0.1793 −0.1208 0.9312 0.9082 1 1 WCM0_PM1 4 57976194 714653150.4365 0.1471 1.1418 1.0729 1 1 WCM0_PM1 4 71467297 73615956 −0.0935−0.4072 NA NA NA NA WCM0_PM1 4 73923944 75971460 0.4857 0.1981 NA NA NANA WCM0_PM1 4 76407857 77637502 0.186 −0.1137 0.9484 0.9001 1 1 WCM0_PM14 77651910 83276513 0.4687 0.1805 1.1333 1.1333 1 1 WCM0_PM1 4 8327784584390210 0.1327 −0.1694 0.9292 0.8492 1 1 WCM0_PM1 4 84391521 1039128080.3901 0.0989 1.081 1.061 1 1 WCM0_PM1 4 103947532 106158545 0.0074−0.3009 NA NA NA NA WCM0_PM1 4 106290955 106604173 −1.1952 −1.6032 NA NANA NA WCM0_PM1 4 106604462 177073054 0.0382 −0.2685 1.0647 0.5956 1 1WCM0_PM1 4 177077313 178911620 −1.251 −1.6663 NA NA NA NA WCM0_PM1 4183090528 190947555 −0.0435 −0.3544 0.9873 0.577 1 1 WCM0_PM1 5 1404801489877 0.388 0.0968 1.0883 1.0505 1 1 WCM0_PM1 5 1494933 9630007 0.61380.3307 1.2784 1.2368 1 1 WCM0_PM1 5 10227737 54529379 0.3988 0.1081.0889 1.0665 1 1 WCM0_PM1 5 54552305 57755768 0.14 −0.1618 NA NA NA NAWCM0_PM1 5 57790431 59901600 0.0145 −0.2935 NA NA NA NA WCM0_PM1 559934574 81572366 −0.1184 −0.4334 0.9845 0.4965 1 0 WCM0_PM1 5 81573511122950100 0.0576 −0.2481 1.0717 0.6122 1 1 WCM0_PM1 5 123966399129072749 −1.2818 −1.7012 0.6127 0.0023 1 0 WCM0_PM1 5 129240561134345063 −0.661 −1.0136 0.9952 −0.0046 1 0 WCM0_PM1 5 134346022136957742 −0.255 −0.5782 1.3265 0.0131 1 0 WCM0_PM1 5 136961483139006407 0.0861 −0.2183 0.8839 0.8352 1 1 WCM0_PM1 5 139060141154065496 0.401 0.1103 1.0794 1.0794 1 1 WCM0_PM1 5 154092593 1598556340.2516 −0.0452 0.9914 0.9469 1 1 WCM0_PM1 5 159912418 170319530 0.45710.1685 1.146 1.1017 1 1 WCM0_PM1 5 170323125 180166834 0.1899 −0.10960.9317 0.922 1 1 WCM0_PM1 5 180166891 180687814 0.4109 0.1205 NA NA NANA WCM0_PM1 6 292608 16328482 0.3718 0.08 1.0658 1.0482 1 1 WCM0_PM1 617283085 18256677 0.0798 −0.2249 NA NA NA NA WCM0_PM1 6 1825829730314271 0.3781 0.0865 1.0673 1.0563 1 1 WCM0_PM1 6 30314598 385620470.225 −0.073 0.9547 0.9467 1 1 WCM0_PM1 6 38565844 41652604 0.471 0.18281.1504 1.1198 1 1 WCM0_PM1 6 41652852 43648896 0.1122 −0.191 0.88240.8696 1 1 WCM0_PM1 6 43655455 73332336 0.4638 0.1754 1.1398 1.1187 1 1WCM0_PM1 6 73713724 74530283 0.1576 −0.1435 NA NA NA NA WCM0_PM1 674533212 86333835 0.415 0.1247 1.1118 1.0688 1 1 WCM0_PM1 6 8634674890605797 0.2209 −0.0772 NA NA NA NA WCM0_PM1 6 90642117 110763540 0.40920.1188 1.0914 1.0802 1 1 WCM0_PM1 6 110763745 112029172 0.1821 −0.11791.0381 0.805 1 1 WCM0_PM1 6 112035620 131211637 0.5123 0.2257 1.17541.1633 1 1 WCM0_PM1 6 131215462 139694266 0.365 0.0729 1.0595 1.0441 1 1WCM0_PM1 6 139694699 149394956 0.5092 0.2225 1.1885 1.145 1 1 WCM0_PM1 6149395274 151789542 0.1674 −0.1332 0.9204 0.9032 1 1 WCM0_PM1 6151789888 158485969 0.382 0.0906 1.0913 1.0382 1 1 WCM0_PM1 6 158487658159650900 0.2458 −0.0513 0.9922 0.9379 1 1 WCM0_PM1 6 159653100170893364 0.5075 0.2207 1.1701 1.1605 1 1 WCM0_PM1 7 193625 48762520.184 −0.1158 0.9229 0.9229 1 1 WCM0_PM1 7 4899606 7278109 −0.059−0.3708 0.7799 0.7668 1 1 WCM0_PM1 7 7278227 22862367 0.4976 0.21051.1798 1.1343 1 1 WCM0_PM1 7 22896231 26903972 0.2648 −0.0315 0.99780.959 1 1 WCM0_PM1 7 27134150 27196110 0.6097 0.3264 NA NA NA NAWCM0_PM1 7 27203255 27689290 −0.37 −0.7006 NA NA NA NA WCM0_PM1 727702390 29160538 0.4743 0.1863 NA NA NA NA WCM0_PM1 7 29394233 38398397−0.4143 −0.748 1.1797 0.0112 1 0 WCM0_PM1 7 38402612 43485137 0.50940.2226 NA NA NA NA WCM0_PM1 7 43490497 45197433 0.274 −0.0219 0.99520.9747 1 1 WCM0_PM1 7 45217038 55565379 0.5408 0.2552 1.212 1.1749 1 1WCM0_PM1 7 55588784 77583111 0.0449 −0.2615 0.8439 0.8246 1 1 WCM0_PM1 777584210 90896080 0.4815 0.1938 1.1687 1.1189 1 1 WCM0_PM1 7 9150307092166221 0.2676 −0.0286 NA NA NA NA WCM0_PM1 7 92195327 97364194 0.50190.2149 1.1631 1.1583 1 1 WCM0_PM1 7 97365650 102608570 0.0075 −0.30090.9227 0.7008 1 1 WCM0_PM1 7 102614133 108213585 0.3001 0.0053 1.00681.0005 1 1 WCM0_PM1 7 108524245 127892028 0.4859 0.1984 1.1605 1.1343 11 WCM0_PM1 7 127894487 131190676 0.1608 −0.14 0.9236 0.8914 1 1 WCM0_PM17 131191055 137612956 0.4359 0.1465 1.1161 1.0977 1 1 WCM0_PM1 7137686457 140710368 0.1109 −0.1923 0.8789 0.8715 1 1 WCM0_PM1 7141255308 144098992 0.5513 0.266 1.3257 1.0793 1 1 WCM0_PM1 7 144101768149152541 0.2014 −0.0976 0.9424 0.9268 1 1 WCM0_PM1 7 149152770150774772 0.429 0.1393 1.1128 1.0899 1 1 WCM0_PM1 7 150775162 1587271220.3006 0.0058 1.0145 0.9936 1 1 WCM0_PM1 7 158734610 158937416 0.62330.3405 NA NA NA NA WCM0_PM1 8 192883 2092894 −3.8743 −5.9454 NA NA NA NAWCM0_PM1 8 2796215 36703373 −0.4713 −0.8091 1.1403 0.0012 1 0 WCM0_PM1 836721957 38688621 0.1375 −0.1644 0.9091 0.8755 1 1 WCM0_PM1 8 3869374241791592 0.3814 0.0899 1.0787 1.0499 1 1 WCM0_PM1 8 41792208 488893440.1528 −0.1484 NA NA NA NA WCM0_PM1 8 48921027 67372603 0.4862 0.19861.1607 1.1345 1 1 WCM0_PM1 8 67372731 68255528 0.1361 −0.166 NA NA NA NAWCM0_PM1 8 68334717 95264305 0.4649 0.1766 1.1419 1.1185 1 1 WCM0_PM1 895265306 105601037 0.3253 0.0315 1.0285 1.0157 1 1 WCM0_PM1 8 106431004120435135 −0.3342 −0.6625 1.2527 0.0109 1 0 WCM0_PM1 8 120435395131249188 −0.5304 −0.8726 1.0905 0.0018 1 0 WCM0_PM1 8 131370344140744432 −0.2546 −0.5777 1.3234 0.0167 1 0 WCM0_PM1 8 140898197144240384 −0.4771 −0.8153 1.1356 0.001 1 0 WCM0_PM1 8 144241646145999910 −0.6384 −0.9892 1.0094 −0.0019 1 0 WCM0_PM1 8 146002848146279508 −0.4378 −0.7732 NA NA NA NA WCM0_PM1 9 117666 3395457 −0.7173−1.0748 0.9436 0.0058 1 0 WCM0_PM1 9 3828235 19032907 0.2456 −0.05151.0616 0.8683 1 1 WCM0_PM1 9 19049648 19597249 −0.6649 −1.0179 NA NA NANA WCM0_PM1 9 19619597 33026828 −0.4495 −0.7857 1.139 0.0211 1 0WCM0_PM1 9 33029893 34506885 −0.7373 −1.0966 NA NA NA NA WCM0_PM1 934512211 35842694 −0.5139 −0.8549 1.11 −0.0042 1 0 WCM0_PM1 9 3584597940772470 −0.6635 −1.0164 0.9735 0.0152 1 0 WCM0_PM1 9 40773337 997970600.1276 −0.1748 0.9638 0.808 1 1 WCM0_PM1 9 99797856 114090601 0.3210.0271 1.0264 1.0115 1 1 WCM0_PM1 9 114124372 116191674 0.0702 −0.2350.8702 0.8292 1 1 WCM0_PM1 9 116224126 116303619 0.2982 0.0033 NA NA NANA WCM0_PM1 9 116345812 123170668 0.468 0.1798 1.1327 1.1327 1 1WCM0_PM1 9 123170795 127265672 0.2489 −0.0481 0.9672 0.9672 1 1 WCM0_PM19 127285000 130476368 0.0975 −0.2063 0.8785 0.8549 1 1 WCM0_PM1 9130476641 134322439 −0.0381 −0.3488 0.7944 0.7762 1 1 WCM0_PM1 9134323136 139402865 0.2149 −0.0835 0.9526 0.9349 1 1 WCM0_PM1 9139403379 140676804 0.0747 −0.2303 0.8596 0.8453 1 1 WCM0_PM1 9140685306 141071438 0.4547 0.166 NA NA NA NA WCM0_PM1 X 2700159 35926100.1448 −0.1568 NA NA NA NA WCM0_PM1 X 3631202 18183347 0.323 0.0292 NANA NA NA WCM0_PM1 X 18189182 24948585 0.1171 −0.1858 NA NA NA NAWCM0_PM1 X 25013914 38664744 0.3986 0.1077 NA NA NA NA WCM0_PM1 X39911398 54569441 0.1373 −0.1647 NA NA NA NA WCM0_PM1 X 5456974469353845 0.4412 0.1519 NA NA NA NA WCM0_PM1 X 69354439 69849453 0.2956 6.00E−04 NA NA NA NA WCM0_PM1 X 69871362 70832741 0.0326 −0.2745 NA NANA NA WCM0_PM1 X 70836210 100662774 0.3119 0.0176 NA NA NA NA WCM0_PM1 X100808315 117053697 0.5443 0.2588 NA NA NA NA WCM0_PM1 X 117054343123234407 0.078 −0.2268 NA NA NA NA WCM0_PM1 X 123480499 1409671610.3668 0.0747 NA NA NA NA WCM0_PM1 X 140969288 152913479 0.6229 0.3401NA NA NA NA WCM0_PM1 X 152913789 154509348 0.2929 −0.0022 NA NA NA NAWCM0_PM2 1 809237 1019882 0.4381 0.4965 1.4423 1.3793 1 1 WCM0_PM2 11021415 2560735 0.0847 0.1373 1.1054 1.0942 1 1 WCM0_PM2 1 29383446253026 0.47 0.5289 1.4648 1.4209 1 1 WCM0_PM2 1 6257789 11986055 0.09640.1492 1.1169 1.1011 1 1 WCM0_PM2 1 11994929 15546134 −0.75 −0.71851.2226 −0.0072 1 0 WCM0_PM2 1 15736699 16782267 −0.9022 −0.8761 1.0982−0.0085 1 0 WCM0_PM2 1 16785343 19609254 −0.6473 −0.6125 1.3083−2.00E−04  1 0 WCM0_PM2 1 19611241 19652872 0.3969 0.4548 NA NA NA NAWCM0_PM2 1 19653099 23346302 0.2334 0.2886 1.2327 1.2103 1 1 WCM0_PM2 123357092 29487055 0.049 0.1009 1.0768 1.0681 1 1 WCM0_PM2 1 2950822032280034 0.3287 0.3854 1.3275 1.285 1 1 WCM0_PM2 1 32280324 334800940.0298 0.0814 1.071 1.0451 1 1 WCM0_PM2 1 33487017 33613286 0.32270.3794 NA NA NA NA WCM0_PM2 1 33623854 35370751 0.6404 0.7015 NA NA NANA WCM0_PM2 1 35370988 41013119 0.1609 0.2149 1.1677 1.1536 1 1 WCM0_PM21 41092296 44750540 0.4095 0.4675 1.4093 1.356 1 1 WCM0_PM2 1 4477406846827425 0.1694 0.2235 NA NA NA NA WCM0_PM2 1 46827456 51875170 0.45290.5115 1.4588 1.3923 1 1 WCM0_PM2 1 51887488 53527948 0.0887 0.1414 NANA NA NA WCM0_PM2 1 53535684 61824888 0.4866 0.5457 1.4597 1.4597 1 1WCM0_PM2 1 61849014 63294767 0.1837 0.2381 1.1998 1.159 1 1 WCM0_PM2 163299775 91182628 0.5166 0.5762 1.4909 1.4909 1 1 WCM0_PM2 1 9138246994027827 −0.7115 −0.6788 1.255 −0.0056 1 0 WCM0_PM2 1 94032886 109159008−0.439 −0.3981 1.5147 0.003 2 0 WCM0_PM2 1 109167265 110019441 −0.7296−0.6975 1.2391 −0.0058 1 0 WCM0_PM2 1 110020456 112991789 −0.3925−0.3504 1.5634 0.0053 2 0 WCM0_PM2 1 112997121 115402411 −0.6649 −0.63061.2975 −0.0057 1 0 WCM0_PM2 1 115403368 119469188 −0.3717 −0.3291 1.5962−0.0041 2 0 WCM0_PM2 1 119474318 150065790 −0.1948 −0.1479 1.232 0.573 11 WCM0_PM2 1 150082704 151239077 −0.4852 −0.4456 NA NA NA NA WCM0_PM2 1151258751 151752629 −0.2369 −0.191 NA NA NA NA WCM0_PM2 1 151753952153520144 0.2668 0.3226 1.7285 0.7727 2 1 WCM0_PM2 1 153520352 155231927−0.2819 −0.237 1.13 0.567 1 1 WCM0_PM2 1 155233071 156337543 −0.4408−0.3999 0.9922 0.5236 1 1 WCM0_PM2 1 156339145 156764618 −0.1454 −0.0974NA NA NA NA WCM0_PM2 1 156767035 160106856 0.1965 0.2512 1.5667 0.8137 21 WCM0_PM2 1 160109420 160793560 0.0495 0.1015 NA NA NA NA WCM0_PM2 1160793962 161487982 −0.2583 −0.2128 NA NA NA NA WCM0_PM2 1 161494726173495771 0.1055 0.1586 1.4731 0.7593 1 1 WCM0_PM2 1 173499026 175037036−0.1316 −0.0833 NA NA NA NA WCM0_PM2 1 175046621 178745891 0.2552 0.31091.6326 0.8483 2 1 WCM0_PM2 1 178753549 180067988 −0.1776 −0.1303 1.16860.6586 1 1 WCM0_PM2 1 180080115 182353636 0.1853 0.2397 1.5856 0.776 2 1WCM0_PM2 1 182354850 185278604 0.0023 0.0533 1.3466 0.7287 1 1 WCM0_PM21 185703989 198828264 0.167 0.2212 1.563 0.7683 2 1 WCM0_PM2 1 199997047205890934 −0.0831 −0.0338 1.2511 0.7026 1 1 WCM0_PM2 1 205892250206822344 0.099 0.1519 NA NA NA NA WCM0_PM2 1 206902448 210111622 0.24080.2961 NA NA NA NA WCM0_PM2 1 210126087 213436143 −0.1164 −0.0678 1.26890.6393 1 1 WCM0_PM2 1 213445947 223934893 0.1067 0.1598 1.4675 0.7668 11 WCM0_PM2 1 223936750 226567827 −0.1439 −0.0959 1.2225 0.6488 1 1WCM0_PM2 1 226568905 233225848 0.3017 0.358 1.3012 1.2621 1 1 WCM0_PM2 1233231500 233394479 −0.7106 −0.6778 NA NA NA NA WCM0_PM2 1 233394735234745243 0.321 0.3777 1.3402 1.2584 1 1 WCM0_PM2 1 235277167 236881136−0.06 −0.0102 1.0041 0.9818 1 1 WCM0_PM2 1 236882331 247902251 0.21790.2729 1.2844 1.1321 1 1 WCM0_PM2 1 247902669 249212574 0.5629 0.62311.7742 1.3061 2 1 WCM0_PM2 10 226048 5454644 −0.3654 −0.3226 1.59260.0067 2 0 WCM0_PM2 10 5468695 11574178 −0.6543 −0.6197 1.3059 −0.0043 10 WCM0_PM2 10 11784598 13629192 −0.9317 −0.9068 1.0761 −0.0093 1 0WCM0_PM2 10 13633835 44866775 −0.6544 −0.6198 1.3018 −3.00E−04  1 0WCM0_PM2 10 44868752 69366602 −0.4147 −0.3732 1.5408 0.0034 2 0 WCM0_PM210 69407203 71139853 −1.0382 −1.0175 0.9981 −0.0101 1 0 WCM0_PM2 1071142230 73767859 −0.5171 −0.4784 1.4316 0.004 1 0 WCM0_PM2 10 7376811376989377 −0.8529 −0.825 1.1365 −0.0075 1 0 WCM0_PM2 10 76993945 93576903−0.4726 −0.4327 1.4778 0.004 1 0 WCM0_PM2 10 93579339 94822686 −0.8672−0.8398 NA NA NA NA WCM0_PM2 10 94822698 98945399 −0.6058 −0.5697 1.34010.0074 1 0 WCM0_PM2 10 98985868 99437681 −0.8439 −0.8157 1.1449 −0.00861 0 WCM0_PM2 10 99437822 101419751 −0.4552 −0.4147 1.4822 0.0181 1 0WCM0_PM2 10 101421333 102240909 −0.8648 −0.8374 1.1223 −0.003 1 0WCM0_PM2 10 102241672 103534966 −0.65 −0.6153 NA NA NA NA WCM0_PM2 10103541462 105363545 −0.8947 −0.8683 1.0978 −0.0022 1 0 WCM0_PM2 10105363568 115537174 −0.4954 −0.456 1.4514 0.0066 1 0 WCM0_PM2 10115540311 124221558 −0.6305 −0.5952 1.3218 0.0021 1 0 WCM0_PM2 10124248397 135373659 −0.4366 −0.3956 1.5173 0.003 2 0 WCM0_PM2 11 1930961776299 −0.7381 −0.7062 1.2203 0.0056 1 0 WCM0_PM2 11 1778573 4389340−0.5592 −0.5217 1.3906 0.0025 1 0 WCM0_PM2 11 4406601 8123112 −0.3063−0.262 1.6626 0.0052 2 0 WCM0_PM2 11 8132293 8953834 −0.5667 −0.5294 NANA NA NA WCM0_PM2 11 8959370 10051332 −0.8664 −0.839 1.1251 −0.0071 1 0WCM0_PM2 11 10052764 18195365 −0.4416 −0.4008 1.5089 0.006 2 0 WCM0_PM211 18195688 18735396 −0.7882 −0.758 1.1902 −0.0076 1 0 WCM0_PM2 1118735645 32460662 −0.3688 −0.3261 1.5969 −0.0016 2 0 WCM0_PM2 1132605479 34668143 −0.7297 −0.6975 1.2403 −0.007 1 0 WCM0_PM2 11 3466824045970516 −0.3951 −0.3531 1.5597 0.0061 2 0 WCM0_PM2 11 45970984 48328644−0.898 −0.8717 1.0964 −0.0034 1 0 WCM0_PM2 11 48346544 61026792 −0.4698−0.4298 1.4746 0.0101 1 0 WCM0_PM2 11 61031994 69488070 −0.8219 −0.79291.1628 −0.0085 1 0 WCM0_PM2 11 69489984 78277277 0.3167 0.3733 1.30321.2874 1 1 WCM0_PM2 11 78279790 107422527 0.5051 0.5645 1.4878 1.4698 11 WCM0_PM2 11 107423881 108398850 0.1316 0.1851 1.1716 1.1022 1 1WCM0_PM2 11 108409842 116767967 0.4131 0.4712 1.4172 1.3553 1 1 WCM0_PM211 116798054 117150696 −0.7617 −0.7306 NA NA NA NA WCM0_PM2 11 117151012118656883 0.1414 0.195 1.2333 1.0562 1 1 WCM0_PM2 11 118754640 119005169−0.8951 −0.8687 NA NA NA NA WCM0_PM2 11 119020673 119181170 0.25680.3125 NA NA NA NA WCM0_PM2 11 119181461 134257469 0.5004 0.5597 1.47851.4695 1 1 WCM0_PM2 12 247582 542453 −0.4631 −0.4229 NA NA NA NAWCM0_PM2 12 547683 1702039 −0.9693 −0.9458 1.0403 −0.0021 1 0 WCM0_PM212 1702508 6232298 −0.5358 −0.4977 1.4223 −0.0058 1 0 WCM0_PM2 126309752 9020489 −0.877 −0.85 1.1127 −0.0032 1 0 WCM0_PM2 12 90207949458927 −0.657 −0.6225 NA NA NA NA WCM0_PM2 12 9459772 9723417 0.17030.2245 NA NA NA NA WCM0_PM2 12 9747940 14839086 −0.6346 −0.5994 1.30580.0143 1 0 WCM0_PM2 12 14840934 25348051 −0.4383 −0.3974 1.5147 0.0038 20 WCM0_PM2 12 25356926 31310984 0.4305 0.4888 1.4431 1.3634 1 1 WCM0_PM212 31354073 33532788 0.0773 0.1298 1.0964 1.0919 1 1 WCM0_PM2 1233535468 40761613 0.5227 0.5823 NA NA NA NA WCM0_PM2 12 4130221748439192 −0.3991 −0.3572 1.5634 −0.002 2 0 WCM0_PM2 12 48440154 52200304−0.8348 −0.8062 1.1523 −0.0086 1 0 WCM0_PM2 12 52200490 53345434 −0.3889−0.3467 1.5689 0.0038 2 0 WCM0_PM2 12 53345536 54069803 −0.8917 −0.86521.107 −0.009 1 0 WCM0_PM2 12 54070026 56184384 −0.5684 −0.5312 NA NA NANA WCM0_PM2 12 56188221 57423088 −0.943 −0.9184 1.066 −0.0078 1 0WCM0_PM2 12 57423197 70740147 −0.6263 −0.5908 1.3271 8.00E−04 1 0WCM0_PM2 12 70747582 93101445 −0.4096 −0.3679 1.5463 0.0035 2 0 WCM0_PM212 93131252 93169934 −0.5518 −0.5141 NA NA NA NA WCM0_PM2 12 93170658102468197 −0.7091 −0.6763 1.2571 −0.0055 1 0 WCM0_PM2 12 102468798109052704 −0.5164 −0.4777 1.4412 −0.0049 1 0 WCM0_PM2 12 109055826110386627 −0.7598 −0.7287 1.213 −0.0061 1 0 WCM0_PM2 12 110389073112846109 −1.0103 −0.9884 NA NA NA NA WCM0_PM2 12 112846514 120208607−0.6454 −0.6105 1.3168 −0.0069 1 0 WCM0_PM2 12 120210698 124270279−1.0063 −0.9843 1.0198 −0.0088 1 0 WCM0_PM2 12 124272559 133779274−0.6314 −0.5961 1.3298 −0.0068 1 0 WCM0_PM2 13 19705470 19969295 −0.5235−0.4849 NA NA NA NA WCM0_PM2 13 19971966 33349222 −0.6452 −0.6104 1.317−0.0069 1 0 WCM0_PM2 13 33590659 40229956 −0.4166 −0.3752 1.5435 −0.00142 0 WCM0_PM2 13 40233592 53298200 −0.5766 −0.5396 1.3751 8.00E−04 1 0WCM0_PM2 13 53307540 80911729 −0.4451 −0.4044 1.5074 0.0036 2 0 WCM0_PM213 84453646 95226999 0.7035 0.7654 NA NA NA NA WCM0_PM2 13 95228632101287231 0.3783 0.4358 2.6983 0.0071 3 0 WCM0_PM2 13 101287365113333982 0.6338 0.6949 3.2415 −0.004 3 0 WCM0_PM2 13 113337594114285948 0.4412 0.4997 2.8137 0.014 3 0 WCM0_PM2 13 114287464 1150894110.7047 0.7666 3.4058 −0.0032 3 0 WCM0_PM2 14 19553608 20647381 0.54050.6003 1.6252 1.407 2 1 WCM0_PM2 14 20665627 22237322 0.2887 0.3449 1.271.27 1 1 WCM0_PM2 14 22251211 23079740 0.5599 0.62 1.5602 1.5135 2 2WCM0_PM2 14 23235808 23746270 0.1162 0.1694 1.1727 1.0765 1 1 WCM0_PM214 23777099 31598628 0.4127 0.4708 1.3971 1.3746 1 1 WCM0_PM2 1431602579 34419954 0.0442 0.0961 NA NA NA NA WCM0_PM2 14 3490445735871226 −0.5796 −0.5427 NA NA NA NA WCM0_PM2 14 35871727 50069115−0.073 −0.0235 1.3393 0.6283 1 1 WCM0_PM2 14 50074122 51080036 −0.3612−0.3183 NA NA NA NA WCM0_PM2 14 51081232 63856485 −0.0678 −0.0182 1.31610.6589 1 1 WCM0_PM2 14 63858524 65035071 −0.3643 −0.3215 NA NA NA NAWCM0_PM2 14 65041171 73418579 −0.0856 −0.0363 1.3077 0.6426 1 1 WCM0_PM214 73420880 74707840 −0.4792 −0.4394 0.9527 0.5222 1 1 WCM0_PM2 1474711883 77818103 −0.2283 −0.1822 1.1889 0.5739 1 1 WCM0_PM2 14 7784335378288805 −0.4023 −0.3604 1.0603 0.4976 1 0 WCM0_PM2 14 78325573 819940700.0155 0.0668 NA NA NA NA WCM0_PM2 14 82000095 89082155 0.3685 0.4259 NANA NA NA WCM0_PM2 14 89082590 94089185 0.1862 0.2407 1.1863 1.1767 1 1WCM0_PM2 14 94097247 95267286 0.5257 0.5854 1.5415 1.4594 2 1 WCM0_PM214 95556963 95599740 −0.6165 −0.5808 NA NA NA NA WCM0_PM2 14 95658093102276329 0.4049 0.4628 1.3908 1.3657 1 1 WCM0_PM2 14 102323076104552124 0.0325 0.0842 1.0709 1.0493 1 1 WCM0_PM2 14 104559028107283105 0.2789 0.3349 1.3472 1.1754 1 1 WCM0_PM2 15 20169898 23932084−0.1619 −0.1142 1.2317 0.616 1 1 WCM0_PM2 15 23932260 28377413 0.19860.2532 1.5762 0.8076 2 1 WCM0_PM2 15 28377971 40707140 −0.0021 0.04891.3815 0.6874 1 1 WCM0_PM2 15 40707588 42059254 −0.4075 −0.3658 NA NA NANA WCM0_PM2 15 42067557 42503974 −0.0202 0.0304 1.3494 0.6931 1 1WCM0_PM2 15 42509989 45059999 −0.2733 −0.2282 NA NA NA NA WCM0_PM2 1545120750 45983200 −0.0691 −0.0195 NA NA NA NA WCM0_PM2 15 4787358250474900 0.1632 0.2172 1.5079 0.8171 2 1 WCM0_PM2 15 50475141 63921025−0.0687 −0.0191 1.3061 0.6675 1 1 WCM0_PM2 15 63922860 66853490 −0.3027−0.2584 NA NA NA NA WCM0_PM2 15 66853613 74554874 −0.0152 0.0355 1.34580.704 1 1 WCM0_PM2 15 74559109 76303519 −0.203 −0.1563 1.1956 0.599 1 1WCM0_PM2 15 76426603 79237324 −0.0695 −0.0199 1.3175 0.6551 1 1 WCM0_PM215 79254502 82431166 0.1529 0.2068 1.5464 0.7618 2 1 WCM0_PM2 1582443923 90119458 −0.0493  7.00E−04 1.3221 0.6789 1 1 WCM0_PM2 1590126121 91560265 −0.2636 −0.2183 1.1324 0.5868 1 1 WCM0_PM2 15 91565391102359182 0.0905 0.1432 1.5183 0.6905 2 1 WCM0_PM2 16 79642 449419−0.6082 −0.5722 1.3385 0.0066 1 0 WCM0_PM2 16 449680 19775443 −0.8279−0.7991 1.158 −0.0085 1 0 WCM0_PM2 16 19800168 20990736 −0.548 −0.5102NA NA NA NA WCM0_PM2 16 20994049 28425387 −0.7768 −0.7462 1.2004 −0.00811 0 WCM0_PM2 16 28426211 31155110 −0.9446 −0.9201 1.0653 −0.0083 1 0WCM0_PM2 16 31157089 31212879 −0.8259 −0.797 NA NA NA NA WCM0_PM2 1631213137 47292608 −0.6745 −0.6405 1.2881 −0.0052 1 0 WCM0_PM2 1647294624 56701839 −0.4839 −0.4443 1.4661 0.0038 1 0 WCM0_PM2 16 5670383466757667 −0.6955 −0.6622 1.2712 −0.0074 1 0 WCM0_PM2 16 6675973570605719 −0.888 −0.8613 1.1099 −0.009 1 0 WCM0_PM2 16 70680876 90162282−0.6486 −0.6138 1.3139 −0.0069 1 0 WCM0_PM2 17 131595 5418817 0.03890.0907 1.0703 1.0594 1 1 WCM0_PM2 17 5421236 7579791 0.2009 0.25561.1938 1.1938 1 1 WCM0_PM2 17 7592190 7951862 −0.7953 −0.7654 NA NA NANA WCM0_PM2 17 7976196 10430347 0.186 0.2405 1.1922 1.1706 1 1 WCM0_PM217 10431137 15687995 0.3593 0.4166 1.3442 1.3253 1 1 WCM0_PM2 1715848702 28029991 0.1934 0.248 1.2938 1.0812 1 1 WCM0_PM2 17 2812095228773049 0.7067 0.7686 NA NA NA NA WCM0_PM2 17 28776701 31098162 −0.8847−0.858 1.1056 −0.0021 1 0 WCM0_PM2 17 31099817 35345866 −0.5523 −0.51461.4031 −0.0031 1 0 WCM0_PM2 17 35346720 38600259 −0.8732 −0.846 1.1204−0.0077 1 0 WCM0_PM2 17 38609360 39913897 −0.5396 −0.5015 1.4106 0.00211 0 WCM0_PM2 17 39914791 39976609 −0.7985 −0.7687 NA NA NA NA WCM0_PM217 39991535 43324269 −0.9335 −0.9086 1.0692 −0.0038 1 0 WCM0_PM2 1743331781 47893178 −0.7807 −0.7502 1.1971 −0.0081 1 0 WCM0_PM2 1747895371 56448242 −0.5894 −0.5528 1.3628 7.00E−04 1 0 WCM0_PM2 1756492800 59853906 −0.8764 −0.8494 1.1132 −0.0031 1 0 WCM0_PM2 1759857753 60742221 −0.07 −0.0204 NA NA NA NA WCM0_PM2 17 6074358365074496 0.1673 0.2214 1.2667 1.065 1 1 WCM0_PM2 17 65074640 66533866−0.0866 −0.0374 1.1455 0.8033 1 1 WCM0_PM2 17 66535469 70120419 0.32450.3812 1.4546 1.1503 1 1 WCM0_PM2 17 70643814 72875693 0.1277 0.18111.2376 1.0299 1 1 WCM0_PM2 17 72877182 75212689 −0.0605 −0.0107 1.08480.9004 1 1 WCM0_PM2 17 75303303 81052264 0.1204 0.1737 1.2313 1.0246 1 1WCM0_PM2 18 47641 14613572 0.8405 0.9039 2.4557 1.2867 2 1 WCM0_PM2 1818539822 22023089 −0.7818 −0.7513 1.1962 −0.0081 1 0 WCM0_PM2 1822025334 74980879 −0.4804 −0.4407 1.4713 0.0023 1 0 WCM0_PM2 18 7675313177287631 0.9451 1.0097 NA NA NA NA WCM0_PM2 18 77439974 78005240 −0.2433−0.1975 NA NA NA NA WCM0_PM2 19 281360 652914 0.2311 0.2863 1.40551.0336 1 1 WCM0_PM2 19 663030 5211578 −0.0514 −0.0015 1.0173 0.9806 1 1WCM0_PM2 19 5212166 6368687 0.0531 0.1051 1.0931 1.0581 1 1 WCM0_PM2 196374267 15053073 0.4013 0.4592 1.7277 1.0218 2 1 WCM0_PM2 19 1505327416437806 0.6325 0.6935 2.0839 1.1505 2 1 WCM0_PM2 19 16472746 194580530.4055 0.4634 1.7454 1.0122 2 1 WCM0_PM2 19 19459774 36113658 0.64170.7028 2.1337 1.1217 2 1 WCM0_PM2 19 36113819 36216177 0.5154 0.575 NANA NA NA WCM0_PM2 19 36216477 39664570 0.409 0.467 1.7652 0.9993 2 1WCM0_PM2 19 39665690 40487134 0.6412 0.7024 2.1149 1.1395 2 1 WCM0_PM219 40504227 41807527 0.5236 0.5833 1.8521 1.1444 2 1 WCM0_PM2 1941808777 42599419 0.7377 0.8 2.1516 1.3307 2 1 WCM0_PM2 19 4259970242730593 0.1036 0.1566 NA NA NA NA WCM0_PM2 19 42736706 42848981 −5.3778−7.6442 NA NA NA NA WCM0_PM2 19 42853725 44160626 0.1038 0.1568 2.2387−0.0091 2 0 WCM0_PM2 19 44169475 45185806 0.7099 0.7719 2.1792 1.2358 21 WCM0_PM2 19 45202505 48643216 0.4064 0.4644 1.762 0.9975 2 1 WCM0_PM219 48646883 50983417 0.0868 0.1395 1.2081 0.9949 1 1 WCM0_PM2 1950983930 52543770 0.406 0.464 1.5767 1.182 2 1 WCM0_PM2 19 5254474356600103 0.2137 0.2686 1.397 1.0123 1 1 WCM0_PM2 19 56600277 587214250.437 0.4955 1.7015 1.118 2 1 WCM0_PM2 19 58723004 59082652 0.09690.1497 1.3014 0.9173 1 1 WCM0_PM2 2 41620 8871156 0.6139 0.6748 1.60441.5882 2 2 WCM0_PM2 2 8871342 15327042 0.2439 0.2993 1.2368 1.2243 1 1WCM0_PM2 2 15330456 23974938 0.1542 0.208 1.5066 0.8036 2 1 WCM0_PM2 223977145 29221025 −0.1946 −0.1477 1.199 0.6064 1 1 WCM0_PM2 2 2922209331805938 0.1896 0.2441 1.5651 0.8037 2 1 WCM0_PM2 2 32093595 32903910−0.3806 −0.3382 NA NA NA NA WCM0_PM2 2 32927910 39509625 −0.0783 −0.02881.2274 0.7331 1 1 WCM0_PM2 2 39513990 42472779 0.4186 0.4768 NA NA NA NAWCM0_PM2 2 42483762 44931420 0.1083 0.1613 1.1513 1.0853 1 1 WCM0_PM2 244933438 61009909 0.3724 0.4298 1.3567 1.3375 1 1 WCM0_PM2 2 6101035862448923 0.0076 0.0588 NA NA NA NA WCM0_PM2 2 62449434 69784043 0.41380.4718 1.3981 1.3756 1 1 WCM0_PM2 2 69870168 70520818 −0.8418 −0.8135 NANA NA NA WCM0_PM2 2 70528100 72958333 −0.4214 −0.3801 1.5335 0.0033 2 0WCM0_PM2 2 72960203 75081407 −0.7837 −0.7534 1.181 0.0054 1 0 WCM0_PM2 275094772 84800638 −0.503 −0.4639 1.4399 0.0102 1 0 WCM0_PM2 2 8480454885133195 −0.6742 −0.6402 NA NA NA NA WCM0_PM2 2 85133552 87000551−0.9695 −0.946 1.0391 −0.001 1 0 WCM0_PM2 2 87013039 90458605 −0.6389−0.6038 1.2943 0.0217 1 0 WCM0_PM2 2 91679084 102505246 0.1344 0.18791.2887 0.9895 1 1 WCM0_PM2 2 102507619 108881794 0.371 0.4285 1.40861.283 1 1 WCM0_PM2 2 108910203 113959008 0.0981 0.151 1.1804 1.0402 1 1WCM0_PM2 2 113976161 116101463 −0.5792 −0.5423 NA NA NA NA WCM0_PM2 2116257146 118578845 0.2226 0.2776 NA NA NA NA WCM0_PM2 2 118579266120020901 0.5646 0.6248 NA NA NA NA WCM0_PM2 2 120059998 1206900880.2745 0.3304 NA NA NA NA WCM0_PM2 2 120692379 135309650 −0.6521 −0.61741.3033 4.00E−04 1 0 WCM0_PM2 2 135470749 136872766 −0.8725 −0.84531.1123 9.00E−04 1 0 WCM0_PM2 2 136873077 149520214 −0.4934 −0.45411.4571 0.0029 1 0 WCM0_PM2 2 149522618 153006717 0.2567 0.3123 1.2721.2114 1 1 WCM0_PM2 2 153032111 170094604 0.503 0.5624 1.4842 1.4692 1 1WCM0_PM2 2 170096215 175432807 0.2795 0.3355 1.2785 1.2452 1 1 WCM0_PM22 175436607 179394776 0.4669 0.5257 1.4601 1.4192 1 1 WCM0_PM2 2179395186 182763572 0.6046 0.6653 1.5956 1.5763 2 2 WCM0_PM2 2 182763844193059282 0.4695 0.5283 1.4759 1.4086 1 1 WCM0_PM2 2 196544752 2029010890.2746 0.3306 1.2716 1.2435 1 1 WCM0_PM2 2 203066301 204732711 −0.067−0.0173 NA NA NA NA WCM0_PM2 2 204735510 218941149 0.4015 0.4594 1.38751.3624 1 1 WCM0_PM2 2 218947871 219691643 0.1014 0.1543 1.131 1.0947 1 1WCM0_PM2 2 219692060 223918019 0.3654 0.4228 1.3609 1.3201 1 1 WCM0_PM22 224462315 231406110 0.1389 0.1926 1.2545 1.0311 1 1 WCM0_PM2 2231406680 232458801 −0.0634 −0.0136 1.0229 0.9582 1 1 WCM0_PM2 2232573394 234344499 −0.7659 −0.735 1.2003 0.0013 1 0 WCM0_PM2 2234345003 234869664 0.2862 0.3423 1.4816 1.0539 1 1 WCM0_PM2 2 234871984241817549 0.464 0.5228 1.4528 1.4207 1 1 WCM0_PM2 2 241826477 2428154830.2499 0.3054 1.2584 1.2132 1 1 WCM0_PM2 20 68336 2444510 0.5053 0.56471.4896 1.4686 1 1 WCM0_PM2 20 2446414 6012026 0.2002 0.2549 1.20421.1823 1 1 WCM0_PM2 20 6012706 26188912 0.5275 0.5872 1.5084 1.4962 2 1WCM0_PM2 20 29845502 35929672 0.0713 0.1237 1.0928 1.0862 1 1 WCM0_PM220 35944804 45633522 0.3928 0.4505 1.379 1.354 1 1 WCM0_PM2 20 4564483852612578 0.1259 0.1793 1.1416 1.1231 1 1 WCM0_PM2 20 52645076 552130660.3151 0.3717 NA NA NA NA WCM0_PM2 20 55745967 60498779 0.5838 0.64421.593 1.5328 2 2 WCM0_PM2 20 60499579 62076018 0.352 0.4091 1.35621.2996 1 1 WCM0_PM2 20 62076743 62631145 0.1298 0.1832 1.147 1.1239 1 1WCM0_PM2 20 62632570 62904798 0.4445 0.5031 NA NA NA NA WCM0_PM2 2110862618 15481365 −0.1172 −0.0686 1.0861 0.8211 1 1 WCM0_PM2 21 1551694432503214 0.4724 0.5314 1.4717 1.4189 1 1 WCM0_PM2 21 32508301 360886640.2095 0.2643 1.2157 1.1864 1 1 WCM0_PM2 21 36164295 37507742 −0.5712−0.5341 NA NA NA NA WCM0_PM2 21 37510159 38538534 0.1265 0.1799 1.1721.0936 1 1 WCM0_PM2 21 38538740 44171297 0.4971 0.5563 1.4944 1.4467 1 1WCM0_PM2 21 44174134 45877032 0.277 0.333 1.3044 1.2148 1 1 WCM0_PM2 2145877279 48084181 0.5395 0.5993 1.5319 1.4981 2 1 WCM0_PM2 22 1625582629099483 −0.6825 −0.6487 1.2763 −7.00E−04  1 0 WCM0_PM2 22 2910791532546979 −0.8693 −0.8419 1.1177 −0.0019 1 0 WCM0_PM2 22 3254809237875356 −0.6799 −0.6461 1.2786 −6.00E−04  1 0 WCM0_PM2 22 3787623140825786 −0.8472 −0.819 1.1353 −0.0016 1 0 WCM0_PM2 22 40827415 43460234−1.0345 −1.0136 1.0007 −0.0101 1 0 WCM0_PM2 22 43464594 51216452 −0.6855−0.6519 1.2801 −0.0073 1 0 WCM0_PM2 3 361508 9290657 −0.3682 −0.32551.5903 0.0058 2 0 WCM0_PM2 3 9406821 10357067 −0.7948 −0.7649 1.1786−0.0015 1 0 WCM0_PM2 3 10359786 31725644 −0.4376 −0.3967 1.5162 0.003 20 WCM0_PM2 3 31744003 33704962 −0.7497 −0.7182 NA NA NA NA WCM0_PM2 333725885 37458982 −0.4893 −0.4498 1.4561 0.0082 1 0 WCM0_PM2 3 3747642739230930 −0.3093 −0.2652 1.6582 0.006 2 0 WCM0_PM2 3 39230976 47050777−0.4807 −0.441 1.4709 0.0023 1 0 WCM0_PM2 3 47058653 50214256 −0.871−0.8437 1.1175 −0.0031 1 0 WCM0_PM2 3 50219843 53378889 −0.5972 −0.56081.3623 −0.0064 1 0 WCM0_PM2 3 53381491 56468749 −0.314 −0.2699 1.65360.0051 2 0 WCM0_PM2 3 56468982 58520863 −0.7424 −0.7107 1.2292 −0.0071 10 WCM0_PM2 3 58552329 68802178 −0.3797 −0.3373 1.5872 −0.0042 2 0WCM0_PM2 3 68929855 73657753 −0.6067 −0.5706 1.3525 −0.0058 1 0 WCM0_PM23 73673442 77526728 0.9528 1.0175 NA NA NA NA WCM0_PM2 3 7753024693761945 0.2885 0.3446 NA NA NA NA WCM0_PM2 3 93768357 122103173 −0.5391−0.501 1.4118 0.0014 1 0 WCM0_PM2 3 122121623 122255103 0.2023 0.257 NANA NA NA WCM0_PM2 3 122255221 125690919 0.3715 0.4289 1.3667 1.3257 1 1WCM0_PM2 3 125694435 127413971 0.601 0.6617 NA NA NA NA WCM0_PM2 3127429452 141206043 0.348 0.405 1.3282 1.3201 1 1 WCM0_PM2 3 141230995142537157 0.0821 0.1346 1.109 1.0866 1 1 WCM0_PM2 3 142539750 1694871510.425 0.4832 1.405 1.3908 1 1 WCM0_PM2 3 169492207 170198338 0.11040.1635 1.128 1.112 1 1 WCM0_PM2 3 170198627 175520909 0.3676 0.4251.3712 1.314 1 1 WCM0_PM2 3 176743354 186572527 0.1134 0.1665 1.1361.1086 1 1 WCM0_PM2 3 186760652 194118667 0.4379 0.4964 1.4235 1.3978 11 WCM0_PM2 3 194118875 195622217 0.1266 0.18 1.1456 1.1202 1 1 WCM0_PM23 195778778 196666296 −0.1561 −0.1083 0.9324 0.9229 1 1 WCM0_PM2 3196669288 197847268 0.1403 0.1939 1.1846 1.1031 1 1 WCM0_PM2 4 534033227431 0.1372 0.1908 1.1518 1.1309 1 1 WCM0_PM2 4 3230443 250139320.4072 0.4651 1.3875 1.3735 1 1 WCM0_PM2 4 25019600 38907405 0.25660.3122 1.2542 1.229 1 1 WCM0_PM2 4 38910338 41270082 −0.1185 −0.070.9546 0.9507 1 1 WCM0_PM2 4 41362921 44631587 −0.6483 −0.6135 1.30685.00E−04 1 0 WCM0_PM2 4 44637911 47850328 0.4606 0.5194 1.4537 1.413 1 1WCM0_PM2 4 47853113 57976148 0.2775 0.3335 1.2831 1.237 1 1 WCM0_PM2 457976304 71384483 0.4799 0.5389 1.4735 1.4323 1 1 WCM0_PM2 4 7138845171895121 0.1101 0.1632 NA NA NA NA WCM0_PM2 4 72102288 73615956 −0.518−0.4793 NA NA NA NA WCM0_PM2 4 73923971 75971400 0.4167 0.4748 NA NA NANA WCM0_PM2 4 76407840 77305817 0.129 0.1825 1.1683 1.1013 1 1 WCM0_PM24 77317514 83280653 0.4495 0.5081 1.4338 1.4107 1 1 WCM0_PM2 4 8329267184397844 0.0412 0.093 1.0688 1.0644 1 1 WCM0_PM2 4 84403382 1039128370.3641 0.4214 1.3487 1.3297 1 1 WCM0_PM2 4 103947511 106158503 −0.02020.0304 NA NA NA NA WCM0_PM2 4 106290950 106474096 −1.3231 −1.3154 NA NANA NA WCM0_PM2 4 106510467 177073032 0.0185 0.0699 1.3417 0.7575 1 1WCM0_PM2 4 177077297 178911607 −1.3584 −1.3525 NA NA NA NA WCM0_PM2 4183090543 190947544 −0.0713 −0.0217 1.2897 0.6804 1 1 WCM0_PM2 5 14059816179313 0.5725 0.6328 1.5742 1.527 2 2 WCM0_PM2 5 16451937 325990950.2707 0.3265 1.2731 1.2349 1 1 WCM0_PM2 5 32712279 36679851 0.52390.5835 1.5304 1.4666 2 1 WCM0_PM2 5 36680713 37697749 0.1979 0.2525 NANA NA NA WCM0_PM2 5 37701236 54552360 0.4912 0.5504 1.4764 1.4526 1 1WCM0_PM2 5 54555771 57879089 0.1975 0.2522 NA NA NA NA WCM0_PM2 557913379 61602285 0.0792 0.1318 NA NA NA NA WCM0_PM2 5 61642953 70952542−0.1147 −0.0661 1.2772 0.6333 1 1 WCM0_PM2 5 71015298 74016240 0.11030.1634 1.4894 0.7505 1 1 WCM0_PM2 5 74016574 81548397 −0.1189 −0.07031.2686 0.6362 1 1 WCM0_PM2 5 81549216 122950042 0.108 0.161 1.46990.7663 1 1 WCM0_PM2 5 123966430 129072878 −1.3823 −1.3777 0.7621 0.00761 0 WCM0_PM2 5 129240668 129521442 −0.3597 −0.3167 NA NA NA NA WCM0_PM25 130495208 134347241 −0.6855 −0.6519 1.2795 −0.0066 1 0 WCM0_PM2 5134364640 136957790 −0.2075 −0.1609 1.7865 0.0025 2 0 WCM0_PM2 5136961400 139189010 0.0576 0.1097 1.0856 1.0724 1 1 WCM0_PM2 5 139189250146741108 0.4133 0.4714 1.3864 1.3864 1 1 WCM0_PM2 5 146750248 1488102520.5864 0.6469 1.588 1.5436 2 2 WCM0_PM2 5 148885195 170818440 0.43280.4912 1.4113 1.3999 1 1 WCM0_PM2 5 170818808 180049837 0.2297 0.28491.2233 1.2134 1 1 WCM0_PM2 5 180051068 180687760 0.5178 0.5774 NA NA NANA WCM0_PM2 6 292608 6654776 0.4794 0.5384 1.4657 1.4391 1 1 WCM0_PM2 67182301 25435878 0.2811 0.3371 1.2838 1.2427 1 1 WCM0_PM2 6 2545020130314365 0.4215 0.4797 1.4058 1.3831 1 1 WCM0_PM2 6 30314567 319482780.1778 0.2321 1.1829 1.1662 1 1 WCM0_PM2 6 32006905 34101236 0.3310.3878 1.3256 1.2911 1 1 WCM0_PM2 6 34210575 37616830 0.1614 0.21541.167 1.1551 1 1 WCM0_PM2 6 37617076 41318671 0.5233 0.5829 1.49791.4979 1 1 WCM0_PM2 6 41533555 43748615 0.0753 0.1277 1.1059 1.0792 1 1WCM0_PM2 6 43749692 70993490 0.5045 0.5639 1.4887 1.4677 1 1 WCM0_PM2 671004035 74530214 0.2601 0.3157 NA NA NA NA WCM0_PM2 6 74533151 862003300.4421 0.5006 1.4578 1.3717 1 1 WCM0_PM2 6 86200811 90718534 0.22230.2773 NA NA NA NA WCM0_PM2 6 91226374 102516195 0.5204 0.58 1.50241.4873 2 1 WCM0_PM2 6 105177519 111888889 0.2684 0.3242 1.2634 1.2405 11 WCM0_PM2 6 111894128 134212899 0.5017 0.5611 1.4783 1.4724 1 1WCM0_PM2 6 134301398 139694619 0.3169 0.3735 1.3916 1.1995 1 1 WCM0_PM26 139694903 149395251 0.5321 0.5918 1.5331 1.4812 2 1 WCM0_PM2 6149691155 151939199 0.1417 0.1954 1.1509 1.1392 1 1 WCM0_PM2 6 152129234154480960 0.453 0.5117 1.4257 1.4257 1 1 WCM0_PM2 6 154481179 1596510260.2834 0.3395 1.3013 1.2293 1 1 WCM0_PM2 6 159652931 170893364 0.55180.6118 1.5313 1.5251 2 2 WCM0_PM2 7 193518 4308362 0.2206 0.2756 1.23641.1847 1 1 WCM0_PM2 7 4490854 6859544 −0.0697 −0.0201 1.0053 0.9671 1 1WCM0_PM2 7 7118608 22768361 0.5423 0.6021 1.5426 1.4934 2 1 WCM0_PM2 722769134 24690101 0.2334 0.2886 NA NA NA NA WCM0_PM2 7 24703212 271961390.5025 0.5618 1.53 1.4223 2 1 WCM0_PM2 7 27203369 27689290 −0.4371−0.3961 NA NA NA NA WCM0_PM2 7 27702390 29160596 0.5652 0.6254 NA NA NANA WCM0_PM2 7 29394302 38398397 −0.4228 −0.3815 1.5289 0.0064 2 0WCM0_PM2 7 38402675 43496010 0.5485 0.6084 NA NA NA NA WCM0_PM2 743503278 45217010 0.2961 0.3523 1.2818 1.2714 1 1 WCM0_PM2 7 4522274255273331 0.5964 0.657 1.5832 1.5704 2 2 WCM0_PM2 7 55433718 777551970.0549 0.107 1.1285 1.0254 1 1 WCM0_PM2 7 77756558 90896096 0.53410.5939 1.5216 1.4971 2 1 WCM0_PM2 7 91503131 92207528 0.2702 0.326 NA NANA NA WCM0_PM2 7 92207673 97364142 0.5544 0.6144 1.5511 1.5108 2 2WCM0_PM2 7 97365604 99710913 0.0722 0.1246 1.0957 1.0846 1 1 WCM0_PM2 799711211 102524002 −0.0935 −0.0444 1.1073 0.8321 1 1 WCM0_PM2 7102524683 102584917 0.1582 0.2121 NA NA NA NA WCM0_PM2 7 102603959102715726 0.4759 0.5349 NA NA NA NA WCM0_PM2 7 102716221 1045466210.3788 0.4363 NA NA NA NA WCM0_PM2 7 104681442 105615426 0.0266 0.0782NA NA NA NA WCM0_PM2 7 105621503 107704435 0.3455 0.4026 1.3259 1.3178 11 WCM0_PM2 7 107706389 127848017 0.5256 0.5853 1.5094 1.4912 2 1WCM0_PM2 7 127892124 131189125 0.157 0.2109 1.1822 1.1327 1 1 WCM0_PM2 7131190736 137686453 0.5076 0.567 1.4964 1.4664 1 1 WCM0_PM2 7 137761363141315352 0.0892 0.1419 1.1202 1.0865 1 1 WCM0_PM2 7 141321512 1440989920.6346 0.6957 1.6509 1.5885 2 2 WCM0_PM2 7 144101738 149152452 0.17670.2309 1.2285 1.1187 1 1 WCM0_PM2 7 149152770 150884185 0.4888 0.54791.4679 1.456 1 1 WCM0_PM2 7 150884203 158707015 0.2909 0.3471 1.28361.2603 1 1 WCM0_PM2 7 158711555 158937481 0.6668 0.7283 NA NA NA NAWCM0_PM2 8 193740 2092737 −4.8937 −6.0467 NA NA NA NA WCM0_PM2 8 279621121824547 −0.5136 −0.4748 1.4447 −0.0056 1 0 WCM0_PM2 8 21827056 22438145−0.7365 −0.7045 1.2262 0.0011 1 0 WCM0_PM2 8 22438929 28210114 −0.5313−0.493 1.4254 −0.0043 1 0 WCM0_PM2 8 28210714 33454887 −0.7347 −0.70261.2366 −0.0077 1 0 WCM0_PM2 8 33827137 36703397 −0.3591 −0.3161 NA NA NANA WCM0_PM2 8 36721992 38705449 0.0878 0.1405 1.1359 1.0686 1 1 WCM0_PM28 38775495 41791584 0.4065 0.4645 1.4358 1.3238 1 1 WCM0_PM2 8 4179208548889262 0.1395 0.1931 NA NA NA NA WCM0_PM2 8 48920992 67342391 0.4830.5421 1.4664 1.4457 1 1 WCM0_PM2 8 67344765 68419129 0.1251 0.1785 NANA NA NA WCM0_PM2 8 68421844 95143138 0.4867 0.5458 1.4717 1.448 1 1WCM0_PM2 8 95158146 105601109 0.2965 0.3528 1.2874 1.2667 1 1 WCM0_PM2 8106430848 120430340 −0.3757 −0.3331 1.582 0.0056 2 0 WCM0_PM2 8120430496 131249188 −0.6385 −0.6034 1.3232 −0.0068 1 0 WCM0_PM2 8131370420 144297217 −0.3734 −0.3308 1.5943 −0.0041 2 0 WCM0_PM2 8144297402 145979616 −0.7233 −0.6909 1.2382 7.00E−04 1 0 WCM0_PM2 8145980050 146279475 −0.411 −0.3694 NA NA NA NA WCM0_PM2 9 117666 3395411−0.817 −0.7878 1.1609 −0.0024 1 0 WCM0_PM2 9 3828261 19032907 0.30810.3646 1.5072 1.0678 2 1 WCM0_PM2 9 19049622 19622297 −0.6964 −0.6631 NANA NA NA WCM0_PM2 9 19785928 32989655 −0.3181 −0.2741 1.6464 0.0076 2 0WCM0_PM2 9 32989933 34520699 −0.6726 −0.6385 NA NA NA NA WCM0_PM2 934521535 35906309 −0.4402 −0.3993 1.5181 −0.0017 2 0 WCM0_PM2 9 3590654340293075 −0.6037 −0.5676 NA NA NA NA WCM0_PM2 9 40772506 1008813310.1458 0.1996 1.2816 1.0151 1 1 WCM0_PM2 9 100887100 107456933 0.34590.403 1.3451 1.2994 1 1 WCM0_PM2 9 107457275 108380338 0.0688 0.12121.1574 1.0178 1 1 WCM0_PM2 9 108382293 114124331 0.2093 0.2642 1.29741.1045 1 1 WCM0_PM2 9 114125923 116303615 0.0101 0.0613 1.1657 0.9211 11 WCM0_PM2 9 116345746 123292368 0.4225 0.4807 1.5186 1.2723 2 1WCM0_PM2 9 123298630 127302473 0.1775 0.2317 1.2603 1.0882 1 1 WCM0_PM29 127306061 130511499 −0.0136 0.0371 1.0512 1.001 1 1 WCM0_PM2 9130511939 132889850 −0.2186 −0.1723 0.9619 0.813 1 1 WCM0_PM2 9132891001 135277524 −0.0585 −0.0087 1.0944 0.8936 1 1 WCM0_PM2 9135277822 139405781 0.1794 0.2337 1.2608 1.0909 1 1 WCM0_PM2 9 139407452140708975 −0.0485 0.0016 1.0736 0.9286 1 1 WCM0_PM2 9 140710405141071438 0.4312 0.4895 NA NA NA NA WCM0_PM2 X 2700163 15863538 0.43810.4965 NA NA NA NA WCM0_PM2 X 15864026 24906098 0.2571 0.3127 NA NA NANA WCM0_PM2 X 24948626 40440276 0.5371 0.5969 NA NA NA NA WCM0_PM2 X40448260 49595646 0.1162 0.1694 NA NA NA NA WCM0_PM2 X 49597153 697497130.4538 0.5124 NA NA NA NA WCM0_PM2 X 69772057 70832671 0.0607 0.1129 NANA NA NA WCM0_PM2 X 70836225 77528378 0.3625 0.4198 NA NA NA NA WCM0_PM2X 77528664 99890621 0.5051 0.5645 NA NA NA NA WCM0_PM2 X 99891701100662873 0.1418 0.1955 NA NA NA NA WCM0_PM2 X 100808315 112053144 0.5820.6424 NA NA NA NA WCM0_PM2 X 112054662 129546769 0.2154 0.2703 NA NA NANA WCM0_PM2 X 129629208 132092501 0.6263 0.6873 NA NA NA NA WCM0_PM2 X132092566 139040189 0.3661 0.4235 NA NA NA NA WCM0_PM2 X 139047571153033144 0.6676 0.7291 NA NA NA NA WCM0_PM2 X 153040516 154509348 0.2940.3502 NA NA NA NA WCM0_T24 1 809089 2560735 0.1375 −0.1435 0.91230.8984 1 1 WCM0_T24 1 2938297 6266717 0.3447 0.0821 1.0643 1.0529 1 1WCM0_T24 1 6267467 11918318 0.1425 −0.1381 0.9127 0.9048 1 1 WCM0_T24 111918542 19609254 −0.6828 −1.074 0.9527 −0.0027 1 0 WCM0_T24 1 1961124120517929 0.3917 0.1329 1.1592 1.0337 1 1 WCM0_T24 1 20810127 280818860.1918 −0.0841 0.9516 0.9351 1 1 WCM0_T24 1 28086069 29424293 −0.0094−0.3053 NA NA NA NA WCM0_T24 1 29435902 29508193 0.1935 −0.0822 NA NA NANA WCM0_T24 1 29520610 32280238 0.3222 0.0578 1.0578 1.0239 1 1 WCM0_T241 32280378 33490000 0.0805 −0.2062 0.8859 0.8478 1 1 WCM0_T24 1 3350239935370870 0.521 0.2719 NA NA NA NA WCM0_T24 1 35452868 41249967 0.1914−0.0846 0.9451 0.941 1 1 WCM0_T24 1 41282985 45116331 0.3722 0.11191.0993 1.0619 1 1 WCM0_T24 1 45120411 46827456 0.1765 −0.1009 0.97020.8948 1 1 WCM0_T24 1 46860149 51787453 0.4195 0.1629 1.1521 1.0869 1 1WCM0_T24 1 51787790 53458951 0.1487 −0.1313 NA NA NA NA WCM0_T24 153480714 62149177 0.4335 0.1779 1.1532 1.1093 1 1 WCM0_T24 1 6216039064011686 0.1996 −0.0756 0.9966 0.9013 1 1 WCM0_T24 1 64017391 911827940.4314 0.1757 1.1332 1.1259 1 1 WCM0_T24 1 91382378 94027785 −0.6639−1.0517 0.9743 −0.0095 1 0 WCM0_T24 1 94033045 109143339 −0.4631 −0.81751.1223 0.0125 1 0 WCM0_T24 1 109148810 109964448 −0.6691 −1.0578 0.9773−0.0166 1 0 WCM0_T24 1 109968982 113063095 −0.3937 −0.7377 1.1943 0.00511 0 WCM0_T24 1 113068733 115488995 −0.6403 −1.0239 0.9785 0.0051 1 0WCM0_T24 1 115489944 120342507 −0.3669 −0.7071 1.1925 0.0327 1 0WCM0_T24 1 120345717 150044289 −0.1372 −0.4476 1.0138 0.4527 1 0WCM0_T24 1 150048377 151237379 −0.3397 −0.6761 NA NA NA NA WCM0_T24 1151237661 151774461 −0.1484 −0.4601 NA NA NA NA WCM0_T24 1 151774824153520245 0.1807 −0.0962 1.2401 0.6308 1 1 WCM0_T24 1 153520352156777124 −0.1787 −0.4941 0.9483 0.4717 1 0 WCM0_T24 1 156779210156816589 0.0331 −0.2584 NA NA NA NA WCM0_T24 1 156818845 1607844720.1245 −0.1577 1.1974 0.5955 1 1 WCM0_T24 1 160786372 161476342 −0.1701−0.4844 NA NA NA NA WCM0_T24 1 161479615 178515005 0.1058 −0.1783 1.17780.5896 1 1 WCM0_T24 1 178716396 181021581 −0.069 −0.3715 1.0155 0.5305 11 WCM0_T24 1 181024368 198721329 0.0601 −0.2286 1.1046 0.6024 1 1WCM0_T24 1 198721900 206782713 −0.0476 −0.3477 1.0023 0.5694 1 1WCM0_T24 1 206784606 209968613 0.151 −0.1287 NA NA NA NA WCM0_T24 1209969902 226465519 −0.0336 −0.3322 1.012 0.5766 1 1 WCM0_T24 1226474132 233192953 0.3159 0.0509 1.0404 1.0314 1 1 WCM0_T24 1 233225848233394376 −0.566 −0.9369 NA NA NA NA WCM0_T24 1 233394644 2475821570.1699 −0.108 0.933 0.9228 1 1 WCM0_T24 1 247582347 249212577 0.3870.1278 1.1056 1.0797 1 1 WCM0_T24 10 226060 5496374 −0.4195 −0.76741.1574 0.0176 1 0 WCM0_T24 10 5496457 44141480 −0.6282 −1.0097 0.9962−0.0029 1 0 WCM0_T24 10 44866767 69281699 −0.4538 −0.8068 1.1242 0.01911 0 WCM0_T24 10 69299327 71008324 −0.9091 −1.3459 0.8104 −0.0235 1 0WCM0_T24 10 71008448 73822733 −0.5091 −0.8707 1.0787 0.0151 1 0 WCM0_T2410 73823909 76788362 −0.7169 −1.1145 0.9168 0.0069 1 0 WCM0_T24 1076788700 93582083 −0.4867 −0.8447 1.0989 0.0148 1 0 WCM0_T24 10 9358687199518939 −0.6192 −0.9991 1.0065 −0.0059 1 0 WCM0_T24 10 99527347101163194 −0.3969 −0.7415 1.1633 0.0329 1 0 WCM0_T24 10 101163614105207136 −0.7053 −1.1008 0.9354 −0.0029 1 0 WCM0_T24 10 105209225120460891 −0.4871 −0.8452 1.0998 0.0134 1 0 WCM0_T24 10 120467052123970523 −0.6855 −1.0773 0.9551 −0.0073 1 0 WCM0_T24 10 123970779135373568 −0.4482 −0.8003 1.1415 0.0069 1 0 WCM0_T24 11 193096 1606274−0.6978 −1.0919 0.9313 0.007 1 0 WCM0_T24 11 1606486 4406616 −0.5142−0.8766 1.0846 0.0046 1 0 WCM0_T24 11 4406920 8118404 −0.3501 −0.68791.2272 0.0142 1 0 WCM0_T24 11 8118740 10215523 −0.6474 −1.0323 0.9888−0.0109 1 0 WCM0_T24 11 10327314 18254013 −0.438 −0.7886 1.1502 0.0076 10 WCM0_T24 11 18257434 18787364 −0.7344 −1.1352 0.9183 −0.0078 1 0WCM0_T24 11 18793489 30921082 −0.3539 −0.6923 1.221 0.0168 1 0 WCM0_T2411 30922081 32610256 −0.4789 −0.8357 NA NA NA NA WCM0_T24 11 3261055033375041 −0.763 −1.1694 NA NA NA NA WCM0_T24 11 33564200 45967678−0.4435 −0.7949 1.1435 0.0092 1 0 WCM0_T24 11 45970479 48177610 −0.7773−1.1865 0.893 −0.0143 1 0 WCM0_T24 11 48181567 61026798 −0.4983 −0.85821.0798 0.0235 1 0 WCM0_T24 11 61031975 69488068 −0.6922 −1.0852 0.9554−0.0127 1 0 WCM0_T24 11 69490020 78285336 0.3058 0.04 1.0337 1.0225 1 1WCM0_T24 11 78369097 101454169 0.4382 0.183 1.1401 1.1303 1 1 WCM0_T2411 101762165 107422626 0.3567 0.0951 1.1097 1.0266 1 1 WCM0_T24 11107423847 108398873 0.1219 −0.1606 0.9663 0.823 1 1 WCM0_T24 11108409859 116827732 0.3641 0.1031 1.0915 1.0567 1 1 WCM0_T24 11116968947 117150677 −0.6868 −1.0788 NA NA NA NA WCM0_T24 11 117151012118656770 0.1064 −0.1777 0.9822 0.786 1 1 WCM0_T24 11 118754701119027624 −0.7219 −1.1204 NA NA NA NA WCM0_T24 11 119029024 1342574940.4017 0.1437 1.1083 1.1012 1 1 WCM0_T24 12 247582 406301 −0.4563−0.8097 NA NA NA NA WCM0_T24 12 416214 1904477 −0.786 −1.197 0.8814−0.009 1 0 WCM0_T24 12 1904945 6080749 −0.4883 −0.8466 1.0994 0.0127 1 0WCM0_T24 12 6085324 9242574 −0.7296 −1.1295 0.914 1.00E−04 1 0 WCM0_T2412 9243032 9458916 −0.5777 −0.9505 NA NA NA NA WCM0_T24 12 94597729723401 0.0023 −0.2924 NA NA NA NA WCM0_T24 12 9748029 25347813 −0.5064−0.8676 1.0802 0.0159 1 0 WCM0_T24 12 25348051 31555611 0.3537 0.09191.0911 1.0404 1 1 WCM0_T24 12 31562177 33022048 0.0587 −0.2302 0.86010.845 1 1 WCM0_T24 12 33030926 41831798 0.3274 0.0634 NA NA NA NAWCM0_T24 12 41871666 49048205 −0.4538 −0.8068 1.1361 0.0072 1 0 WCM0_T2412 49048825 51852444 −0.7323 −1.1328 0.9225 −0.0104 1 0 WCM0_T24 1251853774 53238275 −0.4279 −0.777 1.1455 0.0217 1 0 WCM0_T24 12 5323853654066360 −0.7383 −1.14 0.9139 −0.0064 1 0 WCM0_T24 12 54069803 56119575−0.5037 −0.8644 1.0869 0.0117 1 0 WCM0_T24 12 56119888 57317835 −0.7774−1.1867 0.8824 −0.0038 1 0 WCM0_T24 12 57323333 72338463 −0.5465 −0.91411.0532 0.0082 1 0 WCM0_T24 12 72343458 93101399 −0.4115 −0.7581 1.17450.008 1 0 WCM0_T24 12 93131258 102494798 −0.6339 −1.0163 0.9955 −0.00671 0 WCM0_T24 12 102505843 108917274 −0.5026 −0.8631 1.0923 0.0073 1 0WCM0_T24 12 108918060 110340836 −0.6488 −1.034 0.9929 −0.0162 1 0WCM0_T24 12 110341933 112910759 −0.8715 −1.3001 NA NA NA NA WCM0_T24 12112915680 120565723 −0.6196 −0.9995 0.9945 0.0058 1 0 WCM0_T24 12120567104 124387485 −0.8465 −1.2698 0.8482 −0.0187 1 0 WCM0_T24 12124393840 133779285 −0.6175 −0.9971 1.0096 −0.0076 1 0 WCM0_T24 1319705463 23939346 −0.7052 −1.1005 0.9427 −0.01 1 0 WCM0_T24 13 2394259680911815 −0.5128 −0.875 1.0877 0.0028 1 0 WCM0_T24 13 84453615 1150894110.4437 0.189 2.2687 0.0112 2 0 WCM0_T24 14 19553690 21623076 0.2780.0098 1.009 1.0046 1 1 WCM0_T24 14 21623435 21992629 0.1002 −0.18440.8945 0.8655 1 1 WCM0_T24 14 21992684 23073012 0.4061 0.1485 1.12031.0964 1 1 WCM0_T24 14 23075356 23745071 0.1493 −0.1306 0.9414 0.8854 11 WCM0_T24 14 23745384 31381351 0.3595 0.0981 1.0762 1.0646 1 1 WCM0_T2414 31382817 34419794 0.054 −0.2353 0.8757 0.8233 1 1 WCM0_T24 1434904500 36003864 −0.3346 −0.6703 NA NA NA NA WCM0_T24 14 3600416059107495 −0.0376 −0.3366 0.9492 0.6346 1 1 WCM0_T24 14 59108413 637358800.1546 −0.1248 1.0688 0.7655 1 1 WCM0_T24 14 63747841 73198586 −0.0458−0.3457 0.918 0.6559 1 1 WCM0_T24 14 73220020 75643284 −0.2168 −0.53690.8088 0.5697 1 1 WCM0_T24 14 75745750 83159060 −0.0134 −0.3097 0.9650.6486 1 1 WCM0_T24 14 86087909 93994954 0.1885 −0.0877 0.9503 0.9318 11 WCM0_T24 14 93995629 95236188 0.3623 0.1011 1.0911 1.054 1 1 WCM0_T2414 95236329 95599774 −0.5888 −0.9635 NA NA NA NA WCM0_T24 14 95657975102028718 0.3323 0.0687 1.0863 1.0113 1 1 WCM0_T24 14 102228256107283105 0.1201 −0.1626 0.9032 0.8836 1 1 WCM0_T24 15 20170122 408461750.067 −0.2209 1.0593 0.6567 1 1 WCM0_T24 15 40849445 42058927 −0.2438−0.5674 NA NA NA NA WCM0_T24 15 42059091 45954315 −0.044 −0.3437 0.98230.5938 1 1 WCM0_T24 15 45962146 50475113 0.2078 −0.0667 1.159 0.7507 1 1WCM0_T24 15 50489819 50596307 −0.0257 −0.3235 NA NA NA NA WCM0_T24 1550601880 51217361 −0.3043 −0.6359 NA NA NA NA WCM0_T24 15 5122121664411058 0.0235 −0.269 1.0142 0.6456 1 1 WCM0_T24 15 64415673 66853439−0.1683 −0.4825 NA NA NA NA WCM0_T24 15 66853692 74907946 0.0659 −0.22211.0386 0.676 1 1 WCM0_T24 15 74908121 75983085 −0.1386 −0.4492 0.88080.5842 1 1 WCM0_T24 15 76016672 90173735 0.0431 −0.2473 1.0247 0.6603 11 WCM0_T24 15 90174824 91434738 −0.1375 −0.4479 0.8815 0.5847 1 1WCM0_T24 15 91434958 102359203 0.0919 −0.1935 1.086 0.6629 1 1 WCM0_T2416 79642 3255134 −0.7024 −1.0973 0.943 −0.0082 1 0 WCM0_T24 16 327392919800221 −0.7698 −1.1775 0.8966 −0.0124 1 0 WCM0_T24 16 1983837920873713 −0.5277 −0.8922 NA NA NA NA WCM0_T24 16 20926870 31368419−0.8111 −1.2272 0.8642 −0.0098 1 0 WCM0_T24 16 31368681 47294541 −0.6939−1.0872 0.9759 −0.0345 1 0 WCM0_T24 16 47345354 56920379 −0.4976 −0.85741.0887 0.0153 1 0 WCM0_T24 16 56920969 67335862 −0.6599 −1.047 0.9767−0.0087 1 0 WCM0_T24 16 67337224 70698647 −0.7819 −1.1921 0.8909 −0.01561 0 WCM0_T24 16 70699009 90162224 −0.6244 −1.0052 1.0002 −0.0039 1 0WCM0_T24 17 131595 456587 0.2164 −0.0573 NA NA NA NA WCM0_T24 17 4637345352092 0.0491 −0.2407 0.8482 0.8445 1 1 WCM0_T24 17 5353639 75797950.1721 −0.1056 0.9335 0.9253 1 1 WCM0_T24 17 7592052 7951653 −0.6556−1.042 NA NA NA NA WCM0_T24 17 7976225 28030074 0.1362 −0.1449 0.98470.8241 1 1 WCM0_T24 17 28120978 28773006 0.6456 0.4052 NA NA NA NAWCM0_T24 17 28776656 31094648 −0.7676 −1.1749 0.8986 −0.0128 1 0WCM0_T24 17 31098144 33769270 −0.491 −0.8497 NA NA NA NA WCM0_T24 1733770937 38600272 −0.7385 −1.1402 0.9187 −0.0113 1 0 WCM0_T24 1738609413 39778647 −0.5143 −0.8767 1.0676 0.0217 1 0 WCM0_T24 17 3978048239925402 −0.686 −1.0778 NA NA NA NA WCM0_T24 17 39925678 43320554−0.8083 −1.2238 0.8727 −0.0164 1 0 WCM0_T24 17 43321172 47904814 −0.6735−1.0631 0.9633 −0.0061 1 0 WCM0_T24 17 47915967 56448442 −0.5474 −0.91521.0636 −0.003 1 0 WCM0_T24 17 56492800 59853772 −0.7612 −1.1673 0.9024−0.0119 1 0 WCM0_T24 17 59857668 60749358 0.0304 −0.2613 NA NA NA NAWCM0_T24 17 60751507 65103296 0.2294 −0.0431 0.9864 0.9547 1 1 WCM0_T2417 65103605 66535512 0.0021 −0.2926 0.8426 0.7902 1 1 WCM0_T24 1766536027 70732854 0.3445 0.0819 1.0813 1.0355 1 1 WCM0_T24 17 7084586372951866 0.1855 −0.091 0.9522 0.9255 1 1 WCM0_T24 17 72954334 752126060.0461 −0.244 0.8612 0.8276 1 1 WCM0_T24 17 75303235 81052326 0.1844−0.0922 0.9576 0.9186 1 1 WCM0_T24 18 47641 14613572 0.7001 0.46311.7288 1.0283 2 1 WCM0_T24 18 18539786 21199513 −0.7802 −1.19 NA NA NANA WCM0_T24 18 21209911 74980829 −0.4867 −0.8447 1.0957 0.018 1 0WCM0_T24 18 76753131 77287610 0.776 0.5438 NA NA NA NA WCM0_T24 1877439974 78005267 −0.3226 −0.6566 NA NA NA NA WCM0_T24 19 281360 63748220.0245 −0.2679 0.8388 0.8223 1 1 WCM0_T24 19 6375471 12792570 0.34210.0793 1.3264 0.7867 1 1 WCM0_T24 19 12800085 16797077 0.4346 0.17921.4309 0.8335 1 1 WCM0_T24 19 16799023 19459754 0.3501 0.088 1.34 0.78581 1 WCM0_T24 19 19460048 36248136 0.4963 0.2455 1.4922 0.8788 1 1WCM0_T24 19 36249139 39667174 0.358 0.0965 1.3177 0.8206 1 1 WCM0_T24 1939668305 40486361 0.5675 0.3218 1.5774 0.9224 2 1 WCM0_T24 19 4048658741854387 0.4496 0.1952 1.4221 0.8677 1 1 WCM0_T24 19 41858807 425980300.6505 0.4104 1.5952 1.0628 2 1 WCM0_T24 19 42599534 42730600 −0.0682−0.3706 NA NA NA NA WCM0_T24 19 42734934 42853841 −3.4128 NA NA NA NA NAWCM0_T24 19 42854504 44160724 −0.036 −0.3348 1.612 −0.0262 2 0 WCM0_T2419 44169628 45176162 0.6238 0.3819 1.6338 0.9722 2 1 WCM0_T24 1945179668 48254769 0.4183 0.1616 1.409 0.828 1 1 WCM0_T24 19 4825580451305589 0.1216 −0.161 0.9503 0.8385 1 1 WCM0_T24 19 51322424 527243000.2959 0.0292 1.1201 0.9208 1 1 WCM0_T24 19 52725357 56600168 0.1337−0.1477 1.0046 0.8007 1 1 WCM0_T24 19 56600434 58718482 0.3943 0.13571.3002 0.8971 1 1 WCM0_T24 19 58721414 59082666 0.0276 −0.2645 0.85270.8123 1 1 WCM0_T24 2 41658 9098734 0.4654 0.2123 1.1622 1.1548 1 1WCM0_T24 2 9143675 14774872 0.2506 −0.02 0.9948 0.9776 1 1 WCM0_T24 215307204 21266460 0.1081 −0.1758 1.1566 0.614 1 1 WCM0_T24 2 2397488929240721 −0.0965 −0.4021 1.0132 0.5003 1 1 WCM0_T24 2 29245138 318059950.1345 −0.1468 1.2053 0.6013 1 1 WCM0_T24 2 32093587 38976865 −0.158−0.4709 0.9495 0.4935 1 0 WCM0_T24 2 38977210 61108996 0.2787 0.01051.027 0.9876 1 1 WCM0_T24 2 61118840 62449664 0.0654 −0.2228 NA NA NA NAWCM0_T24 2 62449976 69784099 0.3663 0.1055 1.0852 1.0666 1 1 WCM0_T24 269870070 70692791 −0.761 −1.1671 NA NA NA NA WCM0_T24 2 7089085785108085 −0.5476 −0.9154 1.0535 0.0068 1 0 WCM0_T24 2 85133241 91955350−0.7074 −1.1032 0.9323 −0.0013 1 0 WCM0_T24 2 95537471 96781921 0.2659−0.0034 NA NA NA NA WCM0_T24 2 96789787 113955292 0.1105 −0.1732 1.01250.7613 1 1 WCM0_T24 2 113955511 116257097 −0.5148 −0.8773 NA NA NA NAWCM0_T24 2 116283497 118578844 0.1248 −0.1574 NA NA NA NA WCM0_T24 2118579333 120690074 0.3128 0.0476 1.0839 0.9831 1 1 WCM0_T24 2 120692522149501207 −0.6036 −0.9808 1.0042 0.0092 1 0 WCM0_T24 2 149511635153378459 0.3054 0.0395 1.0489 1.0066 1 1 WCM0_T24 2 153399253 1701011590.4362 0.1809 1.1397 1.1275 1 1 WCM0_T24 2 170101470 176835571 0.27450.0059 1.0238 0.9845 1 1 WCM0_T24 2 176844588 182781201 0.5271 0.27851.2182 1.2078 1 1 WCM0_T24 2 182783427 201682007 0.3616 0.1004 1.08021.0639 1 1 WCM0_T24 2 201682722 204360065 0.1152 −0.168 0.9136 0.8667 11 WCM0_T24 2 204571465 219082176 0.3552 0.0935 1.0727 1.0612 1 1WCM0_T24 2 219090610 219619124 0.1161 −0.167 0.8956 0.8858 1 1 WCM0_T242 219646982 223918019 0.3506 0.0884 1.0862 1.0402 1 1 WCM0_T24 2224462331 232458168 0.0703 −0.2174 0.9719 0.7484 1 1 WCM0_T24 2232458472 234345133 −0.6856 −1.0773 0.9764 −0.0286 1 0 WCM0_T24 2234346085 234656640 0.1846 −0.092 1.092 0.7844 1 1 WCM0_T24 2 234669127234835179 0.2648 −0.0046 NA NA NA NA WCM0_T24 2 234839396 2420096270.3908 0.1319 1.1052 1.0863 1 1 WCM0_T24 2 242011155 242815427 0.182−0.0948 0.9527 0.92 1 1 WCM0_T24 20 68337 871050 0.2776 0.0093 1.01960.9934 1 1 WCM0_T24 20 896672 2315853 0.5108 0.261 1.2138 1.1829 1 1WCM0_T24 20 2315957 5974987 0.2168 −0.0568 0.9635 0.9593 1 1 WCM0_T24 205987094 25485680 0.4355 0.1801 1.1439 1.122 1 1 WCM0_T24 20 2549135035869704 0.1221 −0.1604 0.9056 0.884 1 1 WCM0_T24 20 35879674 453624770.3168 0.0518 1.0444 1.0287 1 1 WCM0_T24 20 45607224 55213066 0.1421−0.1385 0.9294 0.8876 1 1 WCM0_T24 20 55746005 62076743 0.363 0.10191.0732 1.0732 1 1 WCM0_T24 20 62078139 62904807 0.1452 −0.1351 0.92560.8956 1 1 WCM0_T24 21 10862618 11058227 −0.3717 −0.7126 0.6506 0.5698 11 WCM0_T24 21 14917181 32502539 0.3583 0.0969 1.0775 1.0613 1 1 WCM0_T2421 32503187 36164297 0.2056 −0.069 0.9679 0.9387 1 1 WCM0_T24 2136164574 37507740 −0.6003 −0.977 NA NA NA NA WCM0_T24 21 3751021338600529 0.1346 −0.1467 0.9221 0.8845 1 1 WCM0_T24 21 38604704 480842670.3497 0.0875 1.0671 1.0579 1 1 WCM0_T24 22 16255826 31658796 −0.642−1.0259 0.9825 −2.00E−04  1 0 WCM0_T24 22 31662004 32330370 −0.8807−1.3114 NA NA NA NA WCM0_T24 22 32334021 37914053 −0.5936 −0.9692 1.0249−0.0033 1 0 WCM0_T24 22 37914992 39085079 −0.8162 −1.2332 0.8757 −0.0251 0 WCM0_T24 22 39085368 40820409 −0.6413 −1.0251 0.9778 0.005 1 0WCM0_T24 22 40825784 43275156 −0.8492 −1.2731 0.8549 −0.0274 1 0WCM0_T24 22 43278148 51216430 −0.6435 −1.0276 0.9848 −0.0038 1 0WCM0_T24 3 361508 9146339 −0.418 −0.7657 1.1695 0.0069 1 0 WCM0_T24 39166545 10320592 −0.7376 −1.1391 0.9236 −0.0155 1 0 WCM0_T24 3 1032752247049677 −0.4876 −0.8458 1.1084 0.0044 1 0 WCM0_T24 3 47050053 50153065−0.7602 −1.1661 0.894 −0.0028 1 0 WCM0_T24 3 50153356 53531244 −0.5574−0.9268 1.0544 −0.0024 1 0 WCM0_T24 3 53531501 56468768 −0.3432 −0.68011.2292 0.019 1 0 WCM0_T24 3 56469066 58514714 −0.6921 −1.0851 0.9471−0.0043 1 0 WCM0_T24 3 58516383 67548671 −0.3725 −0.7135 1.2133 0.0064 10 WCM0_T24 3 67559239 73432597 −0.5442 −0.9114 1.068 −0.0047 1 0WCM0_T24 3 73433005 73673834 −0.2481 −0.5722 NA NA NA NA WCM0_T24 374313545 77147482 0.7493 0.5154 NA NA NA NA WCM0_T24 3 77526693 937619090.1959 −0.0797 NA NA NA NA WCM0_T24 3 93768348 122103167 −0.51 −0.87181.0849 0.0081 1 0 WCM0_T24 3 122121756 122247301 0.1292 −0.1526 NA NA NANA WCM0_T24 3 122247503 128205673 0.3147 0.0496 1.0462 1.0237 1 1WCM0_T24 3 128292314 129183462 0.0752 −0.2119 0.8777 0.8491 1 1 WCM0_T243 129185754 134967242 0.3099 0.0444 1.057 1.0056 1 1 WCM0_T24 3134968219 138668493 0.1077 −0.1763 NA NA NA NA WCM0_T24 3 138669181141235267 0.3984 0.1401 NA NA NA NA WCM0_T24 3 141248602 1425229330.0832 −0.2031 0.9069 0.8304 1 1 WCM0_T24 3 142523372 178921596 0.29950.0331 1.0399 1.0066 1 1 WCM0_T24 3 178922274 186760562 0.1258 −0.15630.9091 0.8855 1 1 WCM0_T24 3 186760724 194118982 0.3666 0.1058 1.09241.0598 1 1 WCM0_T24 3 194126732 197847227 0.0659 −0.2221 0.9007 0.8139 11 WCM0_T24 4 53403 337555 0.3156 0.0506 NA NA NA NA WCM0_T24 4 3382143208310 0.0627 −0.2258 0.8655 0.8448 1 1 WCM0_T24 4 3208583 389373720.2491 −0.0217 0.9926 0.9776 1 1 WCM0_T24 4 38942552 40832542 −0.0999−0.4059 0.7918 0.7177 1 1 WCM0_T24 4 40892342 41035343 −0.7022 −1.097 NANA NA NA WCM0_T24 4 41259149 41362963 0.3434 0.0807 NA NA NA NA WCM0_T244 41496647 44631587 −0.636 −1.0189 0.9939 −0.0069 1 0 WCM0_T24 444638037 71510108 0.2737 0.0051 1.021 0.9861 1 1 WCM0_T24 4 7151037371895085 0.072 −0.2155 NA NA NA NA WCM0_T24 4 72102372 73615956 −0.4862−0.8442 NA NA NA NA WCM0_T24 4 73923934 75971465 0.3582 0.0967 NA NA NANA WCM0_T24 4 76407774 77305563 0.1524 −0.1272 0.9296 0.9015 1 1WCM0_T24 4 77305818 83278631 0.386 0.1267 1.1001 1.0836 1 1 WCM0_T24 483279947 84518079 0.0918 −0.1937 0.8869 0.8619 1 1 WCM0_T24 4 84518624103947684 0.3198 0.0551 1.0446 1.0333 1 1 WCM0_T24 4 103947754 106158262−0.0101 −0.3061 NA NA NA NA WCM0_T24 4 106158602 106510492 −1.0823−1.5604 NA NA NA NA WCM0_T24 4 106534619 177072960 −0.0261 −0.32381.0107 0.5872 1 1 WCM0_T24 4 177077291 178911678 −1.2754 −1.8075 NA NANA NA WCM0_T24 4 183090538 183603120 −0.1374 −0.4478 NA NA NA NAWCM0_T24 4 183609476 190947578 −0.0746 −0.3777 0.9881 0.5512 1 1WCM0_T24 5 140603 16474952 0.4515 0.1974 1.1639 1.1293 1 1 WCM0_T24 516475290 54439513 0.3184 0.0536 1.0457 1.03 1 1 WCM0_T24 5 5444266357750710 0.0715 −0.216 1.023 0.6988 1 1 WCM0_T24 5 57751173 59893741−0.1041 −0.4106 NA NA NA NA WCM0_T24 5 59894964 68399818 −0.2796 −0.60780.7588 0.5536 1 1 WCM0_T24 5 68400524 68710051 −0.6652 −1.0533 NA NA NANA WCM0_T24 5 68710104 80256726 −0.2892 −0.6187 0.7575 0.5449 1 1WCM0_T24 5 80256869 122950146 −0.18 −0.4955 0.8208 0.5978 1 1 WCM0_T24 5123966430 129072912 −1.254 −1.7796 0.5685 0.014 1 0 WCM0_T24 5 129240742135391326 −0.5939 −0.9695 1.0253 −0.0039 1 0 WCM0_T24 5 135392355139060120 −0.0924 −0.3976 0.8124 0.7058 1 1 WCM0_T24 5 139060275140175562 0.0802 −0.2065 0.9935 0.7398 1 1 WCM0_T24 5 140175856153792464 0.2244 −0.0486 1.0765 0.8573 1 1 WCM0_T24 5 153792616169023745 0.1255 −0.1566 1.0437 0.7505 1 1 WCM0_T24 5 169025580170626733 0.2593 −0.0106 1.0802 0.9052 1 1 WCM0_T24 5 170632548180687804 0.0381 −0.2528 0.9559 0.7225 1 1 WCM0_T24 6 292598 163284790.3317 0.0681 1.0529 1.0438 1 1 WCM0_T24 6 17283144 18264056 0.0779−0.209 NA NA NA NA WCM0_T24 6 18264241 30314231 0.331 0.0673 1.06021.0353 1 1 WCM0_T24 6 30314567 37443173 0.2186 −0.0548 0.969 0.9564 1 1WCM0_T24 6 37443914 41658889 0.4043 0.1465 1.1224 1.0914 1 1 WCM0_T24 641691703 43655479 0.1192 −0.1636 0.9055 0.8801 1 1 WCM0_T24 6 4373851256819326 0.4246 0.1684 1.1298 1.1177 1 1 WCM0_T24 6 56846620 1120208320.2899 0.0227 1.0258 1.0059 1 1 WCM0_T24 6 112021439 149395284 0.36570.1048 1.0823 1.0683 1 1 WCM0_T24 6 149691121 163983034 0.2609 −0.00880.9982 0.9896 1 1 WCM0_T24 6 163984415 170893364 0.4421 0.1873 1.14961.1276 1 1 WCM0_T24 7 193518 4876252 0.158 −0.1211 0.9366 0.9024 1 1WCM0_T24 7 4899543 6859542 −0.0803 −0.3841 0.7816 0.7509 1 1 WCM0_T24 77118575 27196044 0.4006 0.1425 1.1038 1.1038 1 1 WCM0_T24 7 2720338727689281 −0.4076 −0.7537 NA NA NA NA WCM0_T24 7 27702390 29160490 0.47540.223 NA NA NA NA WCM0_T24 7 29394264 38398397 −0.4157 −0.7629 1.15730.0212 1 0 WCM0_T24 7 38402685 39504152 0.4585 0.2049 NA NA NA NAWCM0_T24 7 39504290 45222729 0.2907 0.0235 1.0473 0.9856 1 1 WCM0_T24 745222991 55560124 0.4517 0.1975 1.1554 1.1381 1 1 WCM0_T24 7 5556529277755197 0.0387 −0.2522 0.9193 0.7599 1 1 WCM0_T24 7 77756702 916222780.442 0.1871 1.1385 1.1385 1 1 WCM0_T24 7 91623921 92164259 0.2341−0.038 NA NA NA NA WCM0_T24 7 92166255 97482617 0.4785 0.2264 1.17741.1623 1 1 WCM0_T24 7 97483858 102566778 0.0371 −0.254 0.9441 0.7331 1 1WCM0_T24 7 102572373 107720220 0.2901 0.0229 1.0226 1.0094 1 1 WCM0_T247 107732084 127847910 0.4312 0.1755 1.1294 1.1294 1 1 WCM0_T24 7127892228 129944401 0.1467 −0.1335 0.9186 0.9046 1 1 WCM0_T24 7129945681 137686382 0.3732 0.1129 1.0942 1.0685 1 1 WCM0_T24 7 137761322140534703 0.1512 −0.1285 0.9198 0.9098 1 1 WCM0_T24 7 140549929142836762 0.5145 0.265 1.5109 0.8924 2 1 WCM0_T24 7 142880505 1476006660.399 0.1408 1.1191 1.0858 1 1 WCM0_T24 7 147675067 148951079 0.0842−0.2021 0.9104 0.8282 1 1 WCM0_T24 7 148951208 158727118 0.357 0.09551.0753 1.0615 1 1 WCM0_T24 7 158734619 158937400 0.5529 0.3062 NA NA NANA WCM0_T24 8 192901 2092872 −3.0828 −5.6794 NA NA NA NA WCM0_T24 82796106 36703425 −0.4983 −0.8582 1.1008 0.0024 1 0 WCM0_T24 8 3672202036793429 0.6061 0.363 NA NA NA NA WCM0_T24 8 37553447 38801285 0.1232−0.1592 0.9171 0.8739 1 1 WCM0_T24 8 38803739 41805386 0.3475 0.08521.0803 1.0413 1 1 WCM0_T24 8 41806889 49637377 0.1354 −0.1458 NA NA NANA WCM0_T24 8 49641685 67372732 0.4146 0.1576 1.1263 1.1046 1 1 WCM0_T248 67380528 68396915 0.1581 −0.1209 NA NA NA NA WCM0_T24 8 6841910795178148 0.4153 0.1584 1.1184 1.1136 1 1 WCM0_T24 8 95182589 1040808960.292 0.025 1.0296 1.0053 1 1 WCM0_T24 8 104153171 105601037 0.45830.2047 NA NA NA NA WCM0_T24 8 106430998 120431590 −0.3666 −0.7068 1.20810.0173 1 0 WCM0_T24 8 120435087 131370293 −0.5379 −0.9042 1.0749 −0.00621 0 WCM0_T24 8 131414204 143995671 −0.3561 −0.6948 1.2218 0.0138 1 0WCM0_T24 8 143996318 146106958 −0.6053 −0.9828 1.0171 −0.0051 1 0WCM0_T24 8 146107242 146279416 −0.4039 −0.7495 NA NA NA NA WCM0_T24 9117666 3395519 −0.8783 −1.3084 0.8135 −0.006 1 0 WCM0_T24 9 382831219032907 0.2105 −0.0637 1.1082 0.8055 1 1 WCM0_T24 9 19049846 19622248−0.6775 −1.0678 NA NA NA NA WCM0_T24 9 19786068 32784601 −0.3376 −0.67371.2458 0.008 1 0 WCM0_T24 9 32784838 34500770 −0.5989 −0.9753 NA NA NANA WCM0_T24 9 34501162 35957830 −0.4131 −0.76 1.1717 0.0092 1 0 WCM0_T249 35958062 40784472 −0.5705 −0.9421 1.0507 −0.0098 1 0 WCM0_T24 944174446 116267746 0.1336 −0.1478 1.0639 0.7413 1 1 WCM0_T24 9 116268730123232466 0.3138 0.0487 1.1857 0.8829 1 1 WCM0_T24 9 123234011 1273023670.1534 −0.1261 1.0517 0.7809 1 1 WCM0_T24 9 127306063 128113084 −0.1997−0.5177 NA NA NA NA WCM0_T24 9 128116966 131010236 0.0379 −0.2531 0.94190.7363 1 1 WCM0_T24 9 131012592 134404670 −0.1024 −0.4087 0.8701 0.63651 1 WCM0_T24 9 134404845 139612197 0.1405 −0.1402 1.0416 0.7731 1 1WCM0_T24 9 139616368 140695306 0.0022 −0.2925 0.9213 0.7117 1 1 WCM0_T249 140706038 141071438 0.1908 −0.0852 NA NA NA NA WCM0_T24 X 270014132519915 0.133 −0.1485 NA NA NA NA WCM0_T24 X 32536097 69871339 0.35560.0939 NA NA NA NA WCM0_T24 X 69890292 70814199 0.1097 −0.174 NA NA NANA WCM0_T24 X 70817857 117512337 0.4034 0.1455 NA NA NA NA WCM0_T24 X117521338 123231545 0.1724 −0.1053 NA NA NA NA WCM0_T24 X 123234404154509348 0.3858 0.1266 NA NA NA NA WCM0_T5 1 809001 1021415 0.33610.1036 1.1084 1.0405 1 1 WCM0_T5 1 1022516 2560735 0.0302 −0.2088 0.87150.8591 1 1 WCM0_T5 1 2938283 6219601 0.3556 0.1235 1.1038 1.075 1 1WCM0_T5 1 6228219 11986198 0.039 −0.1998 0.8778 0.8636 1 1 WCM0_T5 111994910 19609254 −0.8478 −1.1155 0.9242 −0.0011 1 0 WCM0_T5 1 1961124119746169 0.3732 0.1414 NA NA NA NA WCM0_T5 1 19775419 26528034 0.0894−0.1481 0.9126 0.8923 1 1 WCM0_T5 1 26528963 29447714 −0.0902 −0.33210.8147 0.774 1 1 WCM0_T5 1 29448035 32279802 0.2146 −0.0203 1.01820.9538 1 1 WCM0_T5 1 32280246 33502357 −0.1065 −0.3488 0.7989 0.7715 1 1WCM0_T5 1 33547888 33613325 0.2332 −0.0013 NA NA NA NA WCM0_T5 133623952 35370962 0.4917 0.262 NA NA NA NA WCM0_T5 1 35452889 412349710.0449 −0.1937 0.8887 0.86 1 1 WCM0_T5 1 41236518 45205559 0.2777 0.04411.052 1.01 1 1 WCM0_T5 1 45206659 46874308 0.0481 −0.1904 0.8988 0.85391 1 WCM0_T5 1 46874770 51001095 0.3621 0.1301 1.1189 1.0698 1 1 WCM0_T51 51005355 51767391 0.1392 −0.0972 NA NA NA NA WCM0_T5 1 5176823053370473 −0.0168 −0.2569 NA NA NA NA WCM0_T5 1 53370644 55207122 0.2083−0.0267 0.9997 0.9636 1 1 WCM0_T5 1 55223425 61849064 0.4829 0.25311.1991 1.1845 1 1 WCM0_T5 1 61869900 63294797 0.0972 −0.1402 0.93060.8842 1 1 WCM0_T5 1 63299695 91182733 0.4192 0.1883 1.1452 1.1336 1 1WCM0_T5 1 91382468 94017978 −0.791 −1.0563 0.9661 −0.0044 1 0 WCM0_T5 194027982 109158978 −0.5243 −0.7793 1.1676 −0.0023 1 0 WCM0_T5 1109167270 110009434 −0.7858 −1.0509 0.9707 −0.0053 1 0 WCM0_T5 1110009736 112998603 −0.4749 −0.7282 1.2028 0.0046 1 0 WCM0_T5 1112998944 115487552 −0.7549 −1.0187 0.9906 −0.0034 1 0 WCM0_T5 1115488952 120056566 −0.4448 −0.6971 1.2381 −0.0045 1 0 WCM0_T5 1120056873 150064093 −0.2725 −0.5194 0.9705 0.4248 1 0 WCM0_T5 1150064406 151238876 −0.503 −0.7573 NA NA NA NA WCM0_T5 1 151239071151746984 −0.2796 −0.5267 NA NA NA NA WCM0_T5 1 151747256 1535202470.1204 −0.1165 1.1968 0.648 1 1 WCM0_T5 1 153520352 154458574 −0.4601−0.7129 0.8175 0.4027 1 0 WCM0_T5 1 154459078 155231545 −0.2556 −0.50210.9168 0.4954 1 0 WCM0_T5 1 155231927 155300288 −0.4005 −0.6514 NA NA NANA WCM0_T5 1 155307495 155904156 −0.603 −0.8608 NA NA NA NA WCM0_T5 1155911607 156777124 −0.3075 −0.5554 0.9026 0.4583 1 0 WCM0_T5 1156778982 157067754 −0.0422 −0.2829 1.0771 0.5667 1 1 WCM0_T5 1157068608 159906707 0.1497 −0.0866 1.2564 0.6271 1 1 WCM0_T5 1 159907546160784472 −0.0021 −0.2418 NA NA NA NA WCM0_T5 1 160786361 161476353−0.3305 −0.5792 NA NA NA NA WCM0_T5 1 161479710 173556910 0.038 −0.20081.1346 0.6056 1 1 WCM0_T5 1 173567210 174926669 −0.2702 −0.5171 NA NA NANA WCM0_T5 1 174927070 178252762 0.2356 0.0012 1.3113 0.6904 1 1 WCM0_T51 178269164 180853153 −0.208 −0.453 0.9881 0.4729 1 0 WCM0_T5 1180885338 182027176 0.2046 −0.0305 NA NA NA NA WCM0_T5 1 182353805185278271 −0.0438 −0.2846 1.0961 0.5458 1 1 WCM0_T5 1 185278604198828264 0.1303 −0.1064 1.2185 0.6394 1 1 WCM0_T5 1 199997036 205814681−0.1259 −0.3687 1.0082 0.5408 1 1 WCM0_T5 1 205817108 211276897 0.121−0.1158 1.1936 0.6521 1 1 WCM0_T5 1 211280545 213436117 −0.2037 −0.44870.97 0.4955 1 0 WCM0_T5 1 213445880 223957600 0.0507 −0.1878 1.18790.568 1 1 WCM0_T5 1 223958179 226128881 −0.284 −0.5312 0.9121 0.4718 1 0WCM0_T5 1 226173012 226465450 −0.0154 −0.2555 NA NA NA NA WCM0_T5 1226474132 233231571 0.2992 0.0661 1.0682 1.0255 1 1 WCM0_T5 1 233270728233394314 −0.6959 −0.9573 NA NA NA NA WCM0_T5 1 233394653 2347452580.3955 0.1642 1.1627 1.0783 1 1 WCM0_T5 1 235277152 236767444 −3.00E−04−0.24 0.8615 0.832 1 1 WCM0_T5 1 236850018 240492808 0.3645 0.13251.1152 1.0772 1 1 WCM0_T5 1 240493895 247611749 0.1968 −0.0384 0.98370.9638 1 1 WCM0_T5 1 247614407 249212577 0.5062 0.2767 1.2767 1.1462 1 1WCM0_T5 10 225960 5436261 −0.487 −0.7407 1.1901 0.0068 1 0 WCM0_T5 105454638 11797455 −0.7504 −1.014 0.9953 −0.0049 1 0 WCM0_T5 10 1180533913639535 −1.0432 −1.3202 0.8121 −0.0111 1 0 WCM0_T5 10 13642272 44141516−0.7185 −0.9808 1.018 −0.0046 1 0 WCM0_T5 10 44866798 64574192 −0.4311−0.6829 1.2405 0.0053 1 0 WCM0_T5 10 64575585 71160713 −1.0437 −1.32070.8106 −0.0099 1 0 WCM0_T5 10 71164832 73826880 −0.5634 −0.8198 1.1347−0.0016 1 0 WCM0_T5 10 73827451 76979129 −0.8936 −1.1634 0.9031 −0.01011 0 WCM0_T5 10 76980586 93579343 −0.5343 −0.7896 1.1595 −0.0024 1 0WCM0_T5 10 93579698 103541535 −0.7305 −0.9933 1.0094 −0.0047 1 0 WCM0_T510 103542007 105792617 −0.9015 −1.1717 0.8961 −0.0083 1 0 WCM0_T5 10105792729 120789726 −0.5383 −0.7938 1.1502 0.0035 1 0 WCM0_T5 10120790032 121693218 −0.8399 −1.1073 NA NA NA NA WCM0_T5 10 122216862135373655 −0.5227 −0.7776 1.169 −0.0023 1 0 WCM0_T5 11 193096 1905194−0.8028 −1.0686 0.9486 0.0049 1 0 WCM0_T5 11 1905538 4388699 −0.613−0.8712 1.0991 −0.0057 1 0 WCM0_T5 11 4388909 8123112 −0.3821 −0.63241.2907 −4.00E−04  1 0 WCM0_T5 11 8132316 8936420 −0.5952 −0.8527 NA NANA NA WCM0_T5 11 8938820 10064374 −0.9552 −1.2278 0.864 −0.0101 1 0WCM0_T5 11 10215503 16812763 −0.4481 −0.7005 1.2321 −0.0013 1 0 WCM0_T511 16816104 18764555 −0.6853 −0.9463 1.0416 −0.0037 1 0 WCM0_T5 1118764866 32421568 −0.3981 −0.6488 1.2763 −7.00E−04  1 0 WCM0_T5 1132438016 34489825 −0.797 −1.0626 0.967 −0.0094 1 0 WCM0_T5 11 3449246445987190 −0.4769 −0.7302 1.2011 0.0045 1 0 WCM0_T5 11 45991469 48632382−0.9474 −1.2197 0.8562 0.0025 1 0 WCM0_T5 11 49059114 57145237 −0.4708−0.724 1.1994 0.0115 1 0 WCM0_T5 11 57146251 57799371 −0.8483 −1.1161 NANA NA NA WCM0_T5 11 57886001 61026442 −0.5285 −0.7836 1.1582 0.0036 1 0WCM0_T5 11 61026668 69488069 −0.8475 −1.1153 0.9292 −0.0059 1 0 WCM0_T511 69489975 78282457 0.2795 0.0459 1.0397 1.025 1 1 WCM0_T5 11 78285483107205604 0.48 0.2501 1.1893 1.1893 1 1 WCM0_T5 11 107207421 1074245480.3327 0.1002 NA NA NA NA WCM0_T5 11 107427631 108380929 0.0656 −0.17250.8982 0.8764 1 1 WCM0_T5 11 108381165 116797969 0.3557 0.1236 1.10831.0706 1 1 WCM0_T5 11 116824796 117150629 −0.8141 −1.0804 NA NA NA NAWCM0_T5 11 117150937 118656779 −0.0946 −0.3366 0.9917 0.5921 1 1 WCM0_T511 118754701 119020778 −0.9085 −1.1789 NA NA NA NA WCM0_T5 11 119020937134257433 0.4266 0.1958 1.1535 1.1372 1 1 WCM0_T5 12 247582 416158−0.3868 −0.6372 NA NA NA NA WCM0_T5 12 416786 1399139 −0.8985 −1.16850.8911 −0.0013 1 0 WCM0_T5 12 1481188 6078426 −0.5044 −0.7587 1.1897−0.0076 1 0 WCM0_T5 12 6080796 9098964 −0.8314 −1.0984 0.935 −9.00E−04 1 0 WCM0_T5 12 9142297 9572689 −0.6076 −0.8656 NA NA NA NA WCM0_T5 129577223 9723401 0.4119 0.1809 NA NA NA NA WCM0_T5 12 9747937 25348033−0.5302 −0.7854 1.1628 −0.0024 1 0 WCM0_T5 12 25357043 31307336 0.40720.176 1.139 1.1206 1 1 WCM0_T5 12 31310937 33022048 −0.0491 −0.29 0.8280.8079 1 1 WCM0_T5 12 33030952 41831706 0.3443 0.112 NA NA NA NA WCM0_T512 41871666 48866585 −0.4873 −0.741 1.1985 −0.0018 1 0 WCM0_T5 1248866694 52082622 −0.9138 −1.1845 0.8865 −0.0066 1 0 WCM0_T5 12 5209339853298695 −0.4757 −0.729 1.2021 0.0045 1 0 WCM0_T5 12 53298769 54070026−0.9478 −1.2201 0.869 −0.0105 1 0 WCM0_T5 12 54105720 56101335 −0.5988−0.8565 NA NA NA NA WCM0_T5 12 56101475 56182879 −0.7342 −0.9971 NA NANA NA WCM0_T5 12 56184305 57109792 −0.992 −1.2665 NA NA NA NA WCM0_T5 1257110037 57975336 −0.7387 −1.0018 1.0031 −0.0043 1 0 WCM0_T5 12 5797566970149212 −0.6443 −0.9037 1.0728 −0.0038 1 0 WCM0_T5 12 70149472 92539210−0.4498 −0.7023 1.2242 0.005 1 0 WCM0_T5 12 92814801 102437898 −0.7468−1.0102 1.0015 −0.0085 1 0 WCM0_T5 12 102439851 108926074 −0.5631−0.8195 1.1361 −0.0028 1 0 WCM0_T5 12 108929147 110238604 −0.7885−1.0536 0.9678 −0.0043 1 0 WCM0_T5 12 110240942 112893828 −1.0856−1.3648 NA NA NA NA WCM0_T5 12 112910754 120580794 −0.7573 −1.02110.9956 −0.0101 1 0 WCM0_T5 12 120582244 124305197 −1.0728 −1.3514 0.791−0.0072 1 0 WCM0_T5 12 124311414 133779327 −0.7403 −1.0035 0.99724.00E−04 1 0 WCM0_T5 13 19705463 19943641 −0.5106 −0.7651 NA NA NA NAWCM0_T5 13 19969256 29275650 −0.7057 −0.9675 1.0326 −0.0098 1 0 WCM0_T513 29278054 30110154 −0.3962 −0.6469 NA NA NA NA WCM0_T5 13 3034137833329987 −0.6315 −0.8904 1.0753 0.0037 1 0 WCM0_T5 13 33332301 40261667−0.4193 −0.6707 1.2547 0.0016 1 0 WCM0_T5 13 40261945 51287351 −0.6425−0.9018 1.0742 −0.0037 1 0 WCM0_T5 13 51417704 80911803 −0.4629 −0.71581.2193 −0.0015 1 0 WCM0_T5 13 84453654 101320989 0.332 0.0995 2.1523−0.0095 2 0 WCM0_T5 13 101322605 113153517 0.535 0.3061 2.468 0.0047 2 0WCM0_T5 13 113158371 115089411 0.3575 0.1254 2.1798 0.0018 2 0 WCM0_T514 19553682 21623602 1.1725 0.9521 2.8047 1.0647 3 1 WCM0_T5 14 2162381121979330 0.8841 0.6603 2.2592 0.9017 2 1 WCM0_T5 14 21990271 221341111.142 0.9213 NA NA NA NA WCM0_T5 14 22167296 23067241 1.3624 1.14383.2153 1.2039 3 1 WCM0_T5 14 23070659 23651943 0.9415 0.7184 2.44160.8491 2 1 WCM0_T5 14 23745172 24046510 1.2389 1.0192 3.0155 1.038 3 1WCM0_T5 14 24108103 29237899 1.5778 1.3611 4.0265 1.1111 4 1 WCM0_T5 1430046610 31348059 1.1696 0.9491 NA NA NA NA WCM0_T5 14 31348684 321427870.6932 0.4667 NA NA NA NA WCM0_T5 14 32257048 34270162 1.0907 0.8694 NANA NA NA WCM0_T5 14 34395110 35872922 −0.5843 −0.8414 NA NA NA NAWCM0_T5 14 35873672 50069112 −0.0999 −0.342 1.0334 0.5445 1 1 WCM0_T5 1450074195 51210989 −0.363 −0.6127 NA NA NA NA WCM0_T5 14 5121479557704033 −0.101 −0.3432 1.0358 0.5408 1 1 WCM0_T5 14 57706296 580332080.0259 −0.2132 NA NA NA NA WCM0_T5 14 58036721 60759244 1.0565 0.83482.4277 1.1396 2 1 WCM0_T5 14 60903757 63735843 0.3731 0.1414 1.12091.085 1 1 WCM0_T5 14 63747800 65007698 −0.3609 −0.6105 NA NA NA NAWCM0_T5 14 65007918 73198508 −0.1076 −0.3499 1.0205 0.5487 1 1 WCM0_T514 73220020 75747539 −0.4002 −0.651 0.8379 0.4357 1 0 WCM0_T5 1475747906 78325640 −0.244 −0.4901 0.9405 0.4835 1 0 WCM0_T5 14 7835343888792740 0.0687 −0.1693 1.1749 0.6036 1 1 WCM0_T5 14 88852166 94171006−0.2024 −0.4473 0.9678 0.499 1 0 WCM0_T5 14 94173034 95236217 0.0831−0.1546 1.2089 0.5878 1 1 WCM0_T5 14 95267286 95599718 −0.6555 −0.9153NA NA NA NA WCM0_T5 14 95657981 102252501 0.3893 0.1578 1.1372 1.094 1 1WCM0_T5 14 102276329 104565303 −0.0048 −0.2446 0.8527 0.8354 1 1 WCM0_T514 104569928 107283105 0.2427 0.0084 1.0243 0.9873 1 1 WCM0_T5 1520170126 40764155 0.3101 0.0771 1.1539 0.956 1 1 WCM0_T5 15 4076440542059384 −0.1217 −0.3645 NA NA NA NA WCM0_T5 15 42067530 42459122 0.31140.0785 1.0785 1.0333 1 1 WCM0_T5 15 42459552 44487265 0.0898 −0.1478 NANA NA NA WCM0_T5 15 44581345 45059648 −0.0229 −0.2632 NA NA NA NAWCM0_T5 15 45059998 47873531 0.2331 −0.0014 NA NA NA NA WCM0_T5 1548052088 50474900 0.5381 0.3092 1.2642 1.2138 1 1 WCM0_T5 15 5047513850546878 0.216 −0.0189 NA NA NA NA WCM0_T5 15 50549576 51216221 −0.1982−0.443 NA NA NA NA WCM0_T5 15 51217475 64204410 0.2561 0.0221 1.02991.0009 1 1 WCM0_T5 15 64216919 66850156 −0.0114 −0.2514 NA NA NA NAWCM0_T5 15 66850373 74709909 0.3137 0.0809 1.0792 1.0361 1 1 WCM0_T5 1574710242 76303530 0.0717 −0.1663 0.9084 0.8738 1 1 WCM0_T5 15 7642655990119328 0.3043 0.0712 1.057 1.0442 1 1 WCM0_T5 15 90119458 915492260.0496 −0.1889 0.8916 0.8629 1 1 WCM0_T5 15 91549586 102359178 0.37490.1431 1.1201 1.0886 1 1 WCM0_T5 16 79642 3107601 −0.8347 −1.1018 0.9377−0.0058 1 0 WCM0_T5 16 3108498 19721858 −0.9429 −1.215 0.8684 −0.0069 10 WCM0_T5 16 19722751 21060901 −0.7026 −0.9643 1.0273 −0.0023 1 0WCM0_T5 16 21061232 25263400 −0.9173 −1.1882 0.8843 −0.0066 1 0 WCM0_T516 25264317 28123223 −0.7756 −1.0402 NA NA NA NA WCM0_T5 16 2812441031195343 −1.0097 −1.285 0.8317 −0.0109 1 0 WCM0_T5 16 31195646 47409828−0.8091 −1.0752 0.9513 −0.0021 1 0 WCM0_T5 16 47462684 56865783 −0.5842−0.8413 1.1222 −0.0059 1 0 WCM0_T5 16 56865950 67335871 −0.8121 −1.07830.9527 −0.0056 1 0 WCM0_T5 16 67337129 70605559 −0.9955 −1.2701 0.8366−0.0074 1 0 WCM0_T5 16 70680877 74330799 −0.6561 −0.9159 1.0639 −0.00391 0 WCM0_T5 16 74334058 75690332 −0.9403 −1.2123 0.8745 −0.0114 1 0WCM0_T5 16 76311574 90162297 −0.7287 −0.9914 1.0107 −0.0047 1 0 WCM0_T517 131595 5392795 −0.0347 −0.2752 0.8322 0.8204 1 1 WCM0_T5 17 54051087579847 0.1231 −0.1138 0.9374 0.911 1 1 WCM0_T5 17 7591984 7951674−0.8109 −1.0771 NA NA NA NA WCM0_T5 17 7976192 10447216 0.1257 −0.11110.9259 0.9259 1 1 WCM0_T5 17 10447442 15644598 0.2943 0.0611 1.06131.0252 1 1 WCM0_T5 17 15645289 28030023 0.1362 −0.1004 1.0214 0.8441 1 1WCM0_T5 17 28120952 28773021 0.7056 0.4793 NA NA NA NA WCM0_T5 1728776721 30981676 −0.9857 −1.2599 0.8464 −0.0112 1 0 WCM0_T5 17 3098626135545279 −0.6683 −0.9286 1.058 −0.0073 1 0 WCM0_T5 17 35545436 38634873−0.9327 −1.2043 0.8788 −0.0109 1 0 WCM0_T5 17 38635981 39912145 −0.6307−0.8896 1.0809 −0.0014 1 0 WCM0_T5 17 39912444 40841608 −0.9844 −1.25850.8432 −0.0073 1 0 WCM0_T5 17 40842225 41599434 −1.1371 −1.419 0.7597−0.0117 1 0 WCM0_T5 17 41601216 47782506 −0.9185 −1.1894 0.8882 −0.01121 0 WCM0_T5 17 47783183 56438267 −0.6746 −0.9352 1.0446 0.0013 1 0WCM0_T5 17 56439912 59853803 −0.9705 −1.2439 0.8507 −0.0062 1 0 WCM0_T517 59857621 60705135 −0.0654 −0.3067 NA NA NA NA WCM0_T5 17 6074200465050071 0.152 −0.0842 0.9558 0.9308 1 1 WCM0_T5 17 65051180 66533846−0.068 −0.3093 0.8409 0.7731 1 1 WCM0_T5 17 66535514 70845930 0.39030.1589 1.1426 1.0903 1 1 WCM0_T5 17 70943913 72959226 0.143 −0.09340.9488 0.9258 1 1 WCM0_T5 17 72959915 75303291 −0.0334 −0.2739 0.83640.8178 1 1 WCM0_T5 17 75316468 81052243 0.1298 −0.1069 0.94 0.9172 1 1WCM0_T5 18 47647 14613577 0.5695 0.3411 1.5254 1.008 2 1 WCM0_T5 1818539805 22017921 −0.8623 −1.1307 0.9233 −0.0099 1 0 WCM0_T5 18 2202054374980817 −0.5141 −0.7687 1.17 0.0039 1 0 WCM0_T5 18 76753131 772876270.5897 0.3617 NA NA NA NA WCM0_T5 18 77439928 78005267 −0.4781 −0.7315NA NA NA NA WCM0_T5 19 281360 498729 0.2626 0.0287 NA NA NA NA WCM0_T519 501743 2796089 −0.0655 −0.3067 0.8168 0.8002 1 1 WCM0_T5 19 27996894960629 −0.1702 −0.4143 0.792 0.7088 1 1 WCM0_T5 19 5032947 6368641−0.0264 −0.2667 0.8593 0.8031 1 1 WCM0_T5 19 6374213 6732035 0.2117−0.0232 1.196 0.7721 1 1 WCM0_T5 19 6732241 14991514 0.3966 0.16531.4617 0.7811 1 1 WCM0_T5 19 14991897 16296545 0.5823 0.3541 1.70670.8497 2 1 WCM0_T5 19 16301381 19466525 0.3941 0.1627 1.4693 0.7695 1 1WCM0_T5 19 19478880 36303720 0.5897 0.3616 1.7326 0.8372 2 1 WCM0_T5 1936304011 39760191 0.4037 0.1725 1.4942 0.7598 1 1 WCM0_T5 19 3976043540487096 0.6451 0.4179 1.7158 0.9562 2 1 WCM0_T5 19 40504314 418543870.5134 0.2841 1.5928 0.8425 2 1 WCM0_T5 19 41858807 42599415 0.76070.5352 1.8782 1.02 2 1 WCM0_T5 19 42599733 42730600 0.1168 −0.1201 NA NANA NA WCM0_T5 19 42740978 42853637 −5.1922 −8.2362 NA NA NA NA WCM0_T519 42854346 44160661 0.1232 −0.1136 1.85 −0.0015 2 0 WCM0_T5 19 4416965145206951 0.736 0.5101 1.8402 1.0081 2 1 WCM0_T5 19 45207392 486409750.4497 0.2193 1.5231 0.8053 2 1 WCM0_T5 19 48643400 50969439 0.1561−0.08 1.0823 0.8098 1 1 WCM0_T5 19 50970897 52538609 0.4143 0.18331.3181 0.9528 1 1 WCM0_T5 19 52543737 56599405 0.2298 −0.0048 1.20420.7892 1 1 WCM0_T5 19 56599668 58601554 0.375 0.1433 1.3373 0.8716 1 1WCM0_T5 19 58639382 59082678 0.0191 −0.2201 0.9842 0.7328 1 1 WCM0_T5 241623 9460492 0.4844 0.2546 1.2391 1.1469 1 1 WCM0_T5 2 9463404 212664240.1294 −0.1073 1.0791 0.7775 1 1 WCM0_T5 2 23974884 29256420 −0.2472−0.4934 0.9303 0.4904 1 0 WCM0_T5 2 29258494 31805986 0.0926 −0.14491.1735 0.6353 1 1 WCM0_T5 2 32093571 32897428 −0.4992 −0.7533 NA NA NANA WCM0_T5 2 32903996 39008990 −0.1662 −0.4101 0.9504 0.5547 1 1 WCM0_T52 39025555 60983586 0.2216 −0.0131 1.0091 0.9727 1 1 WCM0_T5 2 6098737562728589 −0.0439 −0.2847 0.8647 0.7772 1 1 WCM0_T5 2 62729584 697840850.3579 0.1258 1.1111 1.0711 1 1 WCM0_T5 2 69870178 70692791 −0.916−1.1869 NA NA NA NA WCM0_T5 2 70890857 72562126 −0.4427 −0.6949 1.22790.0077 1 0 WCM0_T5 2 72606813 74901675 −0.7292 −0.9919 1.0087 −0.0031 10 WCM0_T5 2 74901986 85051326 −0.4851 −0.7387 1.1997 −0.0012 1 0 WCM0_T52 85059173 91955308 −0.8325 −1.0996 0.9391 −0.0058 1 0 WCM0_T5 295537509 101619146 0.2918 0.0585 1.0637 1.0191 1 1 WCM0_T5 2 101620779102493554 −0.1739 −0.418 NA NA NA NA WCM0_T5 2 102499135 1090038120.1811 −0.0544 1.2629 0.663 1 1 WCM0_T5 2 109065678 113958972 −0.057−0.2981 1.0559 0.5707 1 1 WCM0_T5 2 113976088 116066882 −0.5524 −0.8083NA NA NA NA WCM0_T5 2 116101464 116594317 0.0924 −0.1451 NA NA NA NAWCM0_T5 2 116598398 120690161 0.3209 0.0882 1.1183 1.0078 1 1 WCM0_T5 2120692564 127956991 −0.6041 −0.862 1.1014 −0.001 1 0 WCM0_T5 2 127958890136872586 −0.7322 −0.995 1.0082 −0.0047 1 0 WCM0_T5 2 136872794149522514 −0.4698 −0.7229 1.2071 0.0046 1 0 WCM0_T5 2 149526799153415244 0.2954 0.0622 1.0526 1.0355 1 1 WCM0_T5 2 153417524 1595332010.5026 0.2731 1.2244 1.1924 1 1 WCM0_T5 2 159535142 160824103 0.32230.0896 1.0966 1.0315 1 1 WCM0_T5 2 160825892 170139346 0.5688 0.34041.2854 1.2468 1 1 WCM0_T5 2 170145672 176844577 0.2852 0.0517 1.06291.0101 1 1 WCM0_T5 2 176857114 179393418 0.4971 0.2675 1.2417 1.1658 1 1WCM0_T5 2 179393715 182780509 0.6357 0.4083 1.3339 1.3204 1 1 WCM0_T5 2182780864 193059282 0.4642 0.2341 1.1845 1.1678 1 1 WCM0_T5 2 196544875201535333 0.3324 0.0999 1.0826 1.0608 1 1 WCM0_T5 2 201677926 2043600390.0943 −0.1432 0.9222 0.8888 1 1 WCM0_T5 2 204571465 219082179 0.38870.1572 1.1367 1.0936 1 1 WCM0_T5 2 219090625 219679694 0.0701 −0.1680.9101 0.8701 1 1 WCM0_T5 2 219688582 223918019 0.3587 0.1267 1.12071.0629 1 1 WCM0_T5 2 224462273 232458780 −0.0803 −0.3219 1.0133 0.5867 11 WCM0_T5 2 232573386 234343503 −0.7499 −1.0135 0.9905 2.00E−04 1 0WCM0_T5 2 234344474 234638237 0.0522 −0.1863 1.1118 0.646 1 1 WCM0_T5 2234652130 234835251 0.1903 −0.0451 NA NA NA NA WCM0_T5 2 234839350242003488 0.4525 0.2222 1.1795 1.1534 1 1 WCM0_T5 2 242004333 2428154290.1952 −0.0401 0.9915 0.9537 1 1 WCM0_T5 20 68342 2361665 0.4375 0.20691.1624 1.146 1 1 WCM0_T5 20 2375300 6017803 0.1498 −0.0864 0.9544 0.92931 1 WCM0_T5 20 6021844 25666786 0.4747 0.2448 1.2054 1.1644 1 1 WCM0_T520 25667001 30556187 0.0192 −0.22 NA NA NA NA WCM0_T5 20 3055634731893802 0.1717 −0.0641 0.9996 0.9136 1 1 WCM0_T5 20 31894708 35884833−0.018 −0.2581 0.8371 0.8354 1 1 WCM0_T5 20 35885245 45633591 0.31880.086 1.0647 1.0582 1 1 WCM0_T5 20 45644934 50808209 0.0642 −0.17390.9037 0.8692 1 1 WCM0_T5 20 51589859 55213096 0.2249 −0.0098 NA NA NANA WCM0_T5 20 55746137 60419867 0.5245 0.2954 1.2384 1.216 1 1 WCM0_T520 60427944 62076075 0.3162 0.0833 1.0735 1.0454 1 1 WCM0_T5 20 6207674362700868 0.0642 −0.174 0.8964 0.8764 1 1 WCM0_T5 20 62701070 629049900.5196 0.2904 NA NA NA NA WCM0_T5 21 10862618 32503230 0.4366 0.2061.1617 1.1453 1 1 WCM0_T5 21 32508359 36088748 0.148 −0.0883 0.96850.9127 1 1 WCM0_T5 21 36164460 37507706 −0.6833 −0.9442 NA NA NA NAWCM0_T5 21 37510213 38612782 0.1007 −0.1366 0.9348 0.8846 1 1 WCM0_T5 2138639544 44108030 0.4449 0.2144 1.1603 1.1603 1 1 WCM0_T5 21 4411754145859002 0.1988 −0.0364 1.0119 0.9383 1 1 WCM0_T5 21 45860766 480842730.4117 0.1806 1.1761 1.0907 1 1 WCM0_T5 22 16255826 28315134 −0.743−1.0063 1.0005 −0.0049 1 0 WCM0_T5 22 29092957 32644703 −0.9024 −1.17260.8937 −0.0065 1 0 WCM0_T5 22 32647780 37966641 −0.7222 −0.9846 1.0154−0.0046 1 0 WCM0_T5 22 37967820 39111897 −0.9942 −1.2688 0.8408 −0.01081 0 WCM0_T5 22 39112118 41075695 −0.8442 −1.1118 0.9294 −0.004 1 0WCM0_T5 22 41077028 43442599 −1.0486 −1.3259 0.809 −0.0112 1 0 WCM0_T522 43447870 51216348 −0.7632 −1.0273 0.9863 −0.0051 1 0 WCM0_T5 3 3615089422287 −0.4799 −0.7334 1.2035 −5.00E−04  1 0 WCM0_T5 3 9424993 10357118−0.9042 −1.1745 0.8875 −0.0014 1 0 WCM0_T5 3 10359800 31789625 −0.5516−0.8076 1.1453 −0.0027 1 0 WCM0_T5 3 31871687 33731348 −0.8302 −1.0972NA NA NA NA WCM0_T5 3 33738372 37458982 −0.5982 −0.8558 1.102 0.0031 1 0WCM0_T5 3 37476427 40286017 −0.4444 −0.6966 1.2353 −0.0013 1 0 WCM0_T5 340291743 47050774 −0.6016 −0.8594 1.0999 0.0025 1 0 WCM0_T5 3 4705878350214261 −0.954 −1.2267 0.8647 −0.0101 1 0 WCM0_T5 3 50219843 53381422−0.686 −0.947 1.0465 −0.0091 1 0 WCM0_T5 3 53529240 56468916 −0.3997−0.6505 1.2682 0.0059 1 0 WCM0_T5 3 56598022 58555562 −0.8458 −1.11350.9327 −0.0083 1 0 WCM0_T5 3 58620028 68802060 −0.4303 −0.6821 1.24440.0021 1 0 WCM0_T5 3 68929871 73657708 −0.6472 −0.9067 1.0579 0.0089 1 0WCM0_T5 3 73673435 93761897 0.1302 −0.1065 1.207 0.6507 1 1 WCM0_T5 393768315 113114614 −0.4864 −0.74 1.1993 −0.0018 1 0 WCM0_T5 3 113115489121642048 −0.6339 −0.8929 1.0751 0.0019 1 0 WCM0_T5 3 121642117122103099 −0.5579 −0.8141 NA NA NA NA WCM0_T5 3 122121725 1224059510.2513 0.0172 NA NA NA NA WCM0_T5 3 122411180 124281962 0.4722 0.24221.1852 1.1804 1 1 WCM0_T5 3 124303724 125690994 0.2641 0.0303 1.03891.0035 1 1 WCM0_T5 3 125694535 128205878 0.5664 0.338 1.2986 1.2293 1 1WCM0_T5 3 128292142 129696079 0.1643 −0.0716 0.9661 0.937 1 1 WCM0_T5 3130159196 134967282 0.4507 0.2203 1.1994 1.1306 1 1 WCM0_T5 3 134968251138664459 0.1866 −0.0488 NA NA NA NA WCM0_T5 3 138664743 1412311240.5223 0.2931 NA NA NA NA WCM0_T5 3 141235207 142606548 0.1129 −0.12410.9448 0.8904 1 1 WCM0_T5 3 142607706 169485419 0.4456 0.2152 1.16671.1549 1 1 WCM0_T5 3 169485469 170198063 0.0992 −0.1382 0.9347 0.8827 11 WCM0_T5 3 170198537 182563224 0.3312 0.0986 1.086 1.0555 1 1 WCM0_T5 3182566270 186760657 0.1093 −0.1278 0.9358 0.8946 1 1 WCM0_T5 3 186760715194081532 0.4665 0.2364 1.2092 1.1469 1 1 WCM0_T5 3 194081784 1978473540.0568 −0.1816 0.8908 0.8727 1 1 WCM0_T5 4 53435 338171 0.1375 −0.099 NANA NA NA WCM0_T5 4 343826 3219663 −0.2166 −0.4619 0.9694 0.4827 1 0WCM0_T5 4 3222036 10027542 0.0051 −0.2345 1.1303 0.5697 1 1 WCM0_T5 410077008 25032141 0.4354 0.2047 1.1619 1.1431 1 1 WCM0_T5 4 2512561326432569 0.1237 −0.1131 NA NA NA NA WCM0_T5 4 26483424 38682329 0.44530.2148 1.1912 1.1298 1 1 WCM0_T5 4 38690410 44631587 −0.4687 −0.72180.9254 0.2873 1 0 WCM0_T5 4 44637960 56236295 0.3753 0.1436 1.1373 1.0721 1 WCM0_T5 4 56262374 57976100 0.1379 −0.0986 0.9568 0.911 1 1 WCM0_T54 57976319 71467233 0.4873 0.2576 1.2174 1.1736 1 1 WCM0_T5 4 7146738671895049 0.1161 −0.1209 NA NA NA NA WCM0_T5 4 72102276 73615956 −0.4526−0.7051 NA NA NA NA WCM0_T5 4 73923990 75971359 0.1092 −0.128 NA NA NANA WCM0_T5 4 76407746 77357362 −0.2223 −0.4678 0.929 0.5171 1 1 WCM0_T54 77476790 84406140 0.0901 −0.1475 1.153 0.6526 1 1 WCM0_T5 4 8445795385654760 0.3795 0.1478 NA NA NA NA WCM0_T5 4 85656183 89573149 0.25140.0173 1.0296 0.9945 1 1 WCM0_T5 4 89574099 103947745 0.4441 0.21361.1773 1.1419 1 1 WCM0_T5 4 103949924 106158602 0.0089 −0.2306 NA NA NANA WCM0_T5 4 106290846 106473981 −1.3806 −1.6771 NA NA NA NA WCM0_T5 4106510518 177072944 0.0073 −0.2322 1.1207 0.582 1 1 WCM0_T5 4 177077262178911649 −1.3509 −1.6455 NA NA NA NA WCM0_T5 4 183090470 190947544−0.1117 −0.3541 1.0079 0.5568 1 1 WCM0_T5 5 140480 1494918 0.4271 0.19631.1761 1.1155 1 1 WCM0_T5 5 1501627 9629803 0.6225 0.395 1.347 1.2829 11 WCM0_T5 5 9629973 31541142 0.4235 0.1927 1.1603 1.1254 1 1 WCM0_T5 531541484 32591723 −0.0245 −0.2647 NA NA NA NA WCM0_T5 5 3259903936680713 0.4316 0.2009 1.1857 1.1132 1 1 WCM0_T5 5 36684128 376052560.1121 −0.125 NA NA NA NA WCM0_T5 5 37697813 54555656 0.4576 0.22731.1933 1.148 1 1 WCM0_T5 5 54557146 56558618 0.1665 −0.0694 NA NA NA NAWCM0_T5 5 56777447 57755813 0.3248 0.0921 NA NA NA NA WCM0_T5 5 5779053260999779 0.0791 −0.1588 NA NA NA NA WCM0_T5 5 61602360 68399889 −0.0716−0.313 1.0683 0.5417 1 1 WCM0_T5 5 68400471 70754627 −0.5138 −0.7684 NANA NA NA WCM0_T5 5 70759893 70952634 −0.0792 −0.3209 NA NA NA NA WCM0_T55 71015196 74014140 0.0874 −0.1503 1.1775 0.6246 1 1 WCM0_T5 5 7401464480911327 −0.169 −0.413 0.9756 0.5266 1 1 WCM0_T5 5 80932351 1229500930.0677 −0.1704 1.1813 0.5959 1 1 WCM0_T5 5 123966411 129072749 −1.4002−1.698 0.6076 0.0088 1 0 WCM0_T5 5 129240668 134347241 −0.744 −1.00740.9998 −0.0049 1 0 WCM0_T5 5 134364442 136957844 −0.3017 −0.5495 1.36587.00E−04 1 0 WCM0_T5 5 136961468 139189010 0.0012 −0.2384 0.8989 0.79651 1 WCM0_T5 5 139189310 140174952 0.2075 −0.0275 1.0011 0.9611 1 1WCM0_T5 5 140175184 146080618 0.3725 0.1407 1.1058 1.0991 1 1 WCM0_T5 5146080833 148695769 0.5886 0.3606 1.3009 1.267 1 1 WCM0_T5 5 148697279170814964 0.3541 0.122 1.0915 1.0849 1 1 WCM0_T5 5 170817086 1806877300.1558 −0.0803 0.9546 0.9372 1 1 WCM0_T5 6 292587 6654874 0.3923 0.16091.1282 1.1077 1 1 WCM0_T5 6 7182266 16328478 0.2823 0.0488 1.0555 1.01331 1 WCM0_T5 6 17283149 18258553 −0.0033 −0.2431 NA NA NA NA WCM0_T5 618264068 30314192 0.3373 0.1048 1.083 1.0677 1 1 WCM0_T5 6 3031459831948278 0.1321 −0.1045 0.9368 0.9235 1 1 WCM0_T5 6 32006886 342152210.2571 0.0231 1.0348 0.9975 1 1 WCM0_T5 6 34256548 37438776 0.1004−0.1369 0.9188 0.9002 1 1 WCM0_T5 6 37439670 41710228 0.434 0.20341.1783 1.1244 1 1 WCM0_T5 6 41710989 43742111 0.0285 −0.2105 0.86690.8616 1 1 WCM0_T5 6 43745354 62995719 0.4677 0.2376 1.1874 1.1706 1 1WCM0_T5 6 63990020 72970416 0.072 −0.166 1.1785 0.6041 1 1 WCM0_T5 672974683 74516792 −0.3582 −0.6077 NA NA NA NA WCM0_T5 6 7451783786199223 0.0205 −0.2187 1.0934 0.6253 1 1 WCM0_T5 6 86200393 90605580−0.2047 −0.4497 NA NA NA NA WCM0_T5 6 90605688 102511911 0.1094 −0.12781.2006 0.6299 1 1 WCM0_T5 6 102516262 109699187 −0.1445 −0.3878 1.04280.4857 1 0 WCM0_T5 6 109700823 110759943 0.0382 −0.2006 1.1347 0.6057 11 WCM0_T5 6 110760088 111912850 −0.28 −0.5272 NA NA NA NA WCM0_T5 6111913064 131190710 0.1183 −0.1187 1.2308 0.6113 1 1 WCM0_T5 6 131191147139694553 −0.0404 −0.281 1.1283 0.5177 1 1 WCM0_T5 6 139694845 1493952010.1163 −0.1206 1.2206 0.6189 1 1 WCM0_T5 6 149691115 152201804 −0.3078−0.5558 0.9108 0.4498 1 0 WCM0_T5 6 152265330 159465156 −0.0773 −0.31881.0697 0.5337 1 1 WCM0_T5 6 159590665 170893364 0.0827 −0.155 1.19850.5978 1 1 WCM0_T5 7 193546 4854888 0.1376 −0.099 0.9423 0.9251 1 1WCM0_T5 7 4855804 7118635 −0.1542 −0.3978 0.7793 0.7387 1 1 WCM0_T5 77274011 23015831 0.4973 0.2678 1.2162 1.1917 1 1 WCM0_T5 7 2301640624331250 0.1181 −0.1188 NA NA NA NA WCM0_T5 7 24663462 27196069 0.44980.2194 1.1962 1.1323 1 1 WCM0_T5 7 27203312 27689281 −0.4206 −0.6721 NANA NA NA WCM0_T5 7 27702390 29160637 0.4446 0.2142 NA NA NA NA WCM0_T5 729394275 38398363 −0.4683 −0.7213 1.2147 −0.0016 1 0 WCM0_T5 7 3840260339504327 0.5472 0.3184 NA NA NA NA WCM0_T5 7 39606016 48035664 0.28310.0496 1.0466 1.0234 1 1 WCM0_T5 7 48045605 55565396 0.5439 0.31511.2744 1.2137 1 1 WCM0_T5 7 55588758 77584157 −0.0109 −0.2508 0.92130.7595 1 1 WCM0_T5 7 77648671 89793914 0.662 0.4351 1.3877 1.3163 1 1WCM0_T5 7 89794026 92164223 0.3163 0.0835 1.0693 1.0498 1 1 WCM0_T5 792166211 97365628 0.7269 0.501 1.4596 1.3706 1 1 WCM0_T5 7 9736916399769838 0.216 −0.0188 1.0837 0.8903 1 1 WCM0_T5 7 99771618 1020981290.0647 −0.1735 1.0409 0.7325 1 1 WCM0_T5 7 102098330 102584920 0.2001−0.035 NA NA NA NA WCM0_T5 7 102604130 107704419 0.4795 0.2496 1.33281.045 1 1 WCM0_T5 7 107706389 127847944 0.6966 0.4702 1.5526 1.218 2 1WCM0_T5 7 127892259 129921926 0.2838 0.0504 1.157 0.9141 1 1 WCM0_T5 7129929506 137761334 0.5697 0.3413 1.4034 1.1305 1 1 WCM0_T5 7 137773291140549976 0.2426 0.0083 1.1238 0.8877 1 1 WCM0_T5 7 140624314 1476006040.7231 0.4971 1.6204 1.2023 2 1 WCM0_T5 7 147675028 149152447 0.2201−0.0147 1.1141 0.8656 1 1 WCM0_T5 7 149152770 150940797 0.6194 0.39181.4466 1.1775 1 1 WCM0_T5 7 150945527 158937416 0.44 0.2094 1.20921.1033 1 1 WCM0_T5 8 192877 2092748 −4.7905 −6.5151 NA NA NA NA WCM0_T58 2796243 36703376 −0.6447 −0.9041 1.0725 −0.0038 1 0 WCM0_T5 8 3672194637553655 0.5943 0.3664 NA NA NA NA WCM0_T5 8 37553725 38458696 0.0157−0.2236 NA NA NA NA WCM0_T5 8 38614885 41800506 0.3129 0.08 1.0839 1.031 1 WCM0_T5 8 41801451 48889235 0.0475 −0.1911 NA NA NA NA WCM0_T5 848921068 67342143 0.4449 0.2145 1.1721 1.1485 1 1 WCM0_T5 8 6734238068421839 0.0749 −0.163 NA NA NA NA WCM0_T5 8 68423846 95186078 0.44030.2098 1.1847 1.1282 1 1 WCM0_T5 8 95186439 104078707 0.227 −0.00761.0079 0.9815 1 1 WCM0_T5 8 104080960 105601083 0.4751 0.2451 NA NA NANA WCM0_T5 8 106430808 120575116 −0.4138 −0.6651 1.2544 0.0069 1 0WCM0_T5 8 120577219 131249217 −0.6932 −0.9545 1.0347 −0.0027 1 0 WCM0_T58 131370406 141262869 −0.374 −0.624 1.2914 0.0064 1 0 WCM0_T5 8141285752 142229001 −0.719 −0.9813 1.0229 −0.0099 1 0 WCM0_T5 8142229145 143922636 −0.4404 −0.6925 1.2414 −0.0038 1 0 WCM0_T5 8143927973 146032544 −0.7631 −1.0272 0.9849 −0.0035 1 0 WCM0_T5 8146032848 146279384 −0.4727 −0.726 NA NA NA NA WCM0_T5 9 117666 3395422−1.3193 −1.612 0.6594 −0.0051 1 0 WCM0_T5 9 3828205 19032907 0.0736−0.1643 1.1425 0.6423 1 1 WCM0_T5 9 19049645 19550205 −0.7812 −1.0461 NANA NA NA WCM0_T5 9 19573373 32973499 −0.4051 −0.6561 1.2745 −0.0053 1 0WCM0_T5 9 32973702 34500884 −0.8129 −1.0792 NA NA NA NA WCM0_T5 934501161 35870225 −0.5719 −0.8286 1.1325 −0.0064 1 0 WCM0_T5 9 3590627640772487 −0.7546 −1.0183 NA NA NA NA WCM0_T5 9 40773337 99417031 −0.0483−0.2892 1.0549 0.5818 1 1 WCM0_T5 9 99521250 113704435 0.3778 0.14611.1144 1.0987 1 1 WCM0_T5 9 113734307 116263915 0.1303 −0.1063 0.94130.9166 1 1 WCM0_T5 9 116267817 116303604 0.3412 0.1089 NA NA NA NAWCM0_T5 9 116345866 123234032 0.5368 0.3078 1.2555 1.2202 1 1 WCM0_T5 9123239687 127572700 0.3013 0.0681 1.0516 1.0452 1 1 WCM0_T5 9 127615904128124840 −0.0981 −0.3402 NA NA NA NA WCM0_T5 9 128201226 1302793710.2496 0.0154 1.0365 0.985 1 1 WCM0_T5 9 130280142 131115846 0.0185−0.2207 0.8713 0.845 1 1 WCM0_T5 9 131117342 131830527 −0.1559 −0.39960.7721 0.7441 1 1 WCM0_T5 9 131831378 134404542 0.0387 −0.2001 0.88570.8554 1 1 WCM0_T5 9 134404866 139694251 0.2737 0.04 1.048 1.0082 1 1WCM0_T5 9 139694603 140695352 0.0972 −0.1402 0.9213 0.8935 1 1 WCM0_T5 9140705966 141071438 0.4393 0.2088 NA NA NA NA WCM0_T5 X 2700147 166089820.3254 0.0927 NA NA NA NA WCM0_T5 X 16627816 24906100 0.1207 −0.1162 NANA NA NA WCM0_T5 X 24948585 39934425 0.4371 0.2065 NA NA NA NA WCM0_T5 X39935760 49595653 0.0794 −0.1584 NA NA NA NA WCM0_T5 X 49597268 698987290.3739 0.1421 NA NA NA NA WCM0_T5 X 69902707 70832812 −0.0075 −0.2474 NANA NA NA WCM0_T5 X 70836204 99943341 0.3898 0.1583 NA NA NA NA WCM0_T5 X99944845 100662698 0.0673 −0.1708 NA NA NA NA WCM0_T5 X 100808315112058643 0.5208 0.2917 NA NA NA NA WCM0_T5 X 113965735 129765504 0.1886−0.0468 NA NA NA NA WCM0_T5 X 129768990 132092590 0.597 0.3691 NA NA NANA WCM0_T5 X 132159668 139047663 0.3335 0.1009 NA NA NA NA WCM0_T5 X139585986 152845607 0.6167 0.3891 NA NA NA NA WCM0_T5 X 152913476154509348 0.298 0.0648 NA NA NA NA WCM1 1 14907 193181531 −0.0854−0.3418 0.7918 0.7863 1 1 WCM1 1 193202255 248569369 0.0677 0.13061.0947 1.0947 1 1 WCM1 1 248569587 249213973 −0.1907 −0.7444 0.67810.5157 1 1 WCM1 10 226104 135477928 −0.0735 −0.3011 0.8144 0.8089 1 1WCM1 11 193127 62201391 0.085 0.1779 1.1558 1.1067 1 1 WCM1 11 6225927568675803 −0.0578 −0.2484 0.8418 0.8418 1 1 WCM1 11 68676119 1346059540.081 0.1671 1.1228 1.1228 1 1 WCM1 12 148452 94543591 −0.0792 −0.32060.8227 0.7788 1 1 WCM1 12 94563000 118610483 0.2443 0.5753 1.5346 1.44542 1 WCM1 12 118614980 133810868 −0.2304 −0.9214 1.0465 0.0095 1 0 WCM113 19041937 115089411 0.0416 0.057 1.0403 1.0403 1 1 WCM1 14 19110401107283270 0.0461 0.0698 1.0496 1.0496 1 1 WCM1 15 20083910 102514170−0.0845 −0.3389 0.7906 0.7906 1 1 WCM1 16 64424 66511466 0.0423 0.05881.0416 1.0416 1 1 WCM1 16 66514692 90067176 −0.0891 −0.3547 0.82290.7412 1 1 WCM1 16 90071375 90168842 −0.0027 −0.0739 1.4705 0.4296 1 0WCM1 17 131595 18875062 −0.285 −1.1966 0.9356 −0.063 1 0 WCM1 1718880268 81187850 0.0549 0.0946 1.0678 1.0678 1 1 WCM1 18 47809 780052050.034 0.0351 1.0247 1.0247 1 1 WCM1 19 105021 6496090 −0.2073 −0.81660.9918 0.1438 1 0 WCM1 19 6496259 7929854 0.0968 0.2098 1.1782 1.1348 11 WCM1 19 7933996 10979917 −0.2663 −1.0976 0.9731 −0.0385 1 0 WCM1 1911015622 12164014 0.286 0.6697 1.7391 1.4424 2 1 WCM1 19 1216710714259802 −0.0986 −0.3882 0.8371 0.6911 1 1 WCM1 19 14260473 160332160.5175 1.141 2.9309 1.4797 3 1 WCM1 19 16033280 32844780 −0.195 −0.76320.9789 0.1995 1 0 WCM1 19 32845102 35250928 0.1442 0.3333 1.3687 1.151 11 WCM1 19 35250969 36113853 0.5534 1.2078 3.3131 1.3066 3 1 WCM1 1936120222 36387315 0.1139 0.255 1.2655 1.1213 1 1 WCM1 19 3638771736590554 −0.0848 −0.3397 NA NA NA NA WCM1 19 36591784 49547448 −0.2711−1.1228 0.9633 −0.0449 1 0 WCM1 19 49552028 59093645 0.0055 −0.0490.9666 0.9666 1 1 WCM1 2 41613 272203 −0.0222 −0.1341 NA NA NA NA WCM1 2272346 48706586 −0.0933 −0.3693 0.7742 0.7742 1 1 WCM1 2 48707026119750009 0.0191 −0.0086 0.994 0.994 1 1 WCM1 2 119750148 125627424−0.2428 −0.9807 0.9278 0.0857 1 0 WCM1 2 125660583 243037116 0.04870.0772 1.055 1.055 1 1 WCM1 20 68423 62934541 0.0774 0.1572 1.11511.1151 1 1 WCM1 21 9590370 48084149 0.037 0.0436 1.0307 1.0307 1 1 WCM122 16158973 51223730 0.054 0.092 1.0659 1.0659 1 1 WCM1 3 239314197896800 0.0598 0.1084 1.0781 1.0781 1 1 WCM1 4 53364 134481894 −0.2566−1.0482 0.9928 −0.0256 1 0 WCM1 4 134629278 190882003 0.0343 0.03581.0251 1.0251 1 1 WCM1 5 90680 139422102 0.0331 0.0325 1.0228 1.0228 1 1WCM1 5 139422215 141020563 −0.1658 −0.6416 0.6926 0.5893 1 1 WCM1 5141021110 180687814 0.0766 0.155 1.1134 1.1134 1 1 WCM1 6 20342425983541 −0.1281 −0.4953 0.7412 0.6776 1 1 WCM1 6 25983736 33553364−0.2958 −1.2567 0.9518 −0.1148 1 0 WCM1 6 33554557 170892848 −0.0696−0.2879 0.8191 0.8191 1 1 WCM1 7 193222 44578836 0.0808 0.1666 1.12241.1224 1 1 WCM1 7 44579159 141720790 −0.0124 −0.1035 0.9537 0.9078 1 1WCM1 7 141721479 158937185 0.0998 0.2177 1.4546 0.8711 1 1 WCM1 8 16347042857261 −0.2244 −0.8938 1.0638 0.0126 1 0 WCM1 8 42862972 1462034120.475 1.0601 2.9306 1.2395 3 1 WCM1 8 146203928 146279498 −0.2444−0.9881 NA NA NA NA WCM1 9 14879 141107545 0.0662 0.1263 1.0915 1.0915 11 WCM1 X 2700202 154493576 0.0449 0.0663 NA NA NA NA WCM10 1 14907249213973 0.0209 0.1125 1.0811 1.0811 1 1 WCM10 10 225920 1354778910.0117 0.0637 1.0452 1.0452 1 1 WCM10 11 193096 62303516 0.0559 0.28651.2197 1.2197 1 1 WCM10 11 62327231 66461622 −0.1364 −1.0038 0.49870.4987 0 0 WCM10 11 66461806 134605849 0.032 0.1696 1.1247 1.1247 1 1WCM10 12 148468 133810769 −0.0039 −0.0217 0.9851 0.9851 1 1 WCM10 1319041992 115089411 −0.0161 −0.0917 0.9384 0.9384 1 1 WCM10 14 19110239107283270 −0.0018 −0.0098 0.9932 0.9932 1 1 WCM10 15 20083896 1025062300.0183 0.0988 1.0709 1.0709 1 1 WCM10 16 64432 28944874 0.008 0.04381.0308 1.0308 1 1 WCM10 16 28946817 31276839 −0.2292 −2.4438 0.3876−0.02 0 0 WCM10 16 31277181 90168646 −0.0073 −0.0411 0.9719 0.9719 1 1WCM10 17 131595 81187876 −0.0171 −0.0976 0.9346 0.9346 1 1 WCM10 1847738 78005214 0.0081 0.0445 1.0313 1.0313 1 1 WCM10 19 105080 59093645−0.0447 −0.2678 0.8306 0.8306 1 1 WCM10 2 41672 243037103 0.0077 0.04251.0299 1.0299 1 1 WCM10 20 68319 62959246 0.019 0.1028 1.0738 1.0738 1 1WCM10 21 9590331 48084160 −0.0097 −0.0549 0.9627 0.9627 1 1 WCM10 2216159031 51219089 0.0108 0.0589 1.0416 1.0416 1 1 WCM10 3 239530197896705 0.023 0.1231 1.0891 1.0891 1 1 WCM10 4 53410 190903980 0.00820.0452 1.0319 1.0319 1 1 WCM10 5 90714 180687776 −0.002 −0.0111 0.99230.9923 1 1 WCM10 6 203542 170892848 0.004 0.022 1.0154 1.0154 1 1 WCM107 193171 158937158 0.0161 0.0871 1.0623 1.0623 1 1 WCM10 8 163486146279416 −0.003 −0.0168 0.9884 0.9884 1 1 WCM10 9 20703 1411075130.0308 0.1632 1.1198 1.1198 1 1 WCM10 X 2700084 154509348 0.008 0.0439NA NA NA NA WCM10_Z1-1 1 809001 55541174 −0.0315 −0.0718 0.956 0.9469 11 WCM10_Z1-1 1 55542932 242035537 0.0263 0.0192 1.0197 1.0071 1 1WCM10_Z1-1 1 242042301 244527991 −0.0089 −0.0359 NA NA NA NA WCM10_Z1-11 244538760 246498774 −0.3468 −0.6121 NA NA NA NA WCM10_Z1-1 1 246518360249212577 0.0482 0.0531 1.0679 1.0071 1 1 WCM10_Z1-1 10 225988 1353736060.0099 −0.0065 1.0049 0.9862 1 1 WCM10_Z1-1 11 193112 134257515 0.02190.0123 1.0164 1.0007 1 1 WCM10_Z1-1 12 247582 13768577 −0.0023 −0.02550.9964 0.9686 1 1 WCM10_Z1-1 12 13769433 25260019 −0.4173 −0.7461 1.17910.0134 1 0 WCM10_Z1-1 12 25260760 34179803 0.0406 0.0414 1.045 1.0132 11 WCM10_Z1-1 12 38710870 40499560 −0.5148 −0.942 NA NA NA NA WCM10_Z1-112 40618913 78604198 0.0138 −3.00E−04 0.9998 0.9998 1 1 WCM10_Z1-1 1279611374 80771821 −0.5327 −0.9795 NA NA NA NA WCM10_Z1-1 12 81101468133779274 −0.0274 −0.0652 0.9695 0.9421 1 1 WCM10_Z1-1 13 1974810447470007 0.037 0.0358 1.0426 1.0076 1 1 WCM10_Z1-1 13 48523152 84455666−0.518 −0.9486 1.0412 −0.0049 1 0 WCM10_Z1-1 13 86368301 1150894110.0488 0.0541 1.0654 1.011 1 1 WCM10_Z1-1 14 20215955 107283213 0.0053−0.0137 0.9921 0.989 1 1 WCM10_Z1-1 15 20170134 102359221 −0.1016−0.1849 0.8855 0.8739 1 1 WCM10_Z1-1 16 97558 51098425 −0.0368 −0.08021.0063 0.8856 1 1 WCM10_Z1-1 16 51171110 58768129 −0.6048 −1.136 0.976−0.0659 1 0 WCM10_Z1-1 16 61687521 75281945 −0.022 −0.0566 0.9737 0.94931 1 WCM10_Z1-1 16 75327888 75690482 −0.556 −1.029 NA NA NA NA WCM10_Z1-116 76311635 90161798 −0.0228 −0.0579 0.9668 0.9546 1 1 WCM10_Z1-1 17131595 81052333 −0.0414 −0.0876 0.9456 0.9366 1 1 WCM10_Z1-1 18 4817728739423 −0.0098 −0.0373 0.9898 0.9591 1 1 WCM10_Z1-1 18 2874257629691838 −0.5242 −0.9616 1.0353 −0.0084 1 0 WCM10_Z1-1 18 2969382078005201 0.0411 0.0421 1.0424 1.0169 1 1 WCM10_Z1-1 19 281543 59082725−0.0858 −0.1592 0.9305 0.8605 1 1 WCM10_Z1-1 2 41613 40405612 0.0084−0.0087 1.0017 0.9862 1 1 WCM10_Z1-1 2 40655772 48132817 −0.576 −1.07240.9468 0.0043 1 0 WCM10_Z1-1 2 48573482 176959431 0.0405 0.0412 1.03541.0226 1 1 WCM10_Z1-1 2 176964578 189876437 0.1554 0.2153 1.173 1.1489 11 WCM10_Z1-1 2 189898749 242815390 0.0291 0.0235 1.0212 1.0117 1 1WCM10_Z1-1 20 68413 62904890 −0.0115 −0.04 0.9742 0.9711 1 1 WCM10_Z1-121 10862618 48084207 −0.0062 −0.0317 0.9906 0.9659 1 1 WCM10_Z1-1 2216255872 51216346 −0.0502 −0.1016 0.9873 0.8767 1 1 WCM10_Z1-1 3 361466197765410 0.0273 0.0207 1.0192 1.0097 1 1 WCM10_Z1-1 4 53379 160149210.0226 0.0135 1.0361 0.9827 1 1 WCM10_Z1-1 4 16017861 21950264 −0.4282−0.7672 NA NA NA NA WCM10_Z1-1 4 22389379 115597413 0.049 0.0544 1.04961.0272 1 1 WCM10_Z1-1 4 115750961 129789034 −0.4678 −0.8459 1.05650.0562 1 0 WCM10_Z1-1 4 129792506 175899118 0.0824 0.1055 1.0824 1.06931 1 WCM10_Z1-1 4 176556074 183594243 −0.4166 −0.7447 NA NA NA NAWCM10_Z1-1 4 183600901 190947518 0.0437 0.0462 1.0517 1.0134 1 1WCM10_Z1-1 5 140814 98240677 0.0399 0.0403 1.0363 1.0203 1 1 WCM10_Z1-15 98262023 102895806 −0.3639 −0.644 NA NA NA NA WCM10_Z1-1 5 106716929180687854 0.033 0.0296 1.0239 1.0176 1 1 WCM10_Z1-1 6 292547 1708928480.0481 0.0529 1.0421 1.0325 1 1 WCM10_Z1-1 7 193657 6731061 −0.0725−0.1376 0.9267 0.8914 1 1 WCM10_Z1-1 7 6731298 55269511 0.0624 0.07491.0581 1.0484 1 1 WCM10_Z1-1 7 55270250 76797175 −0.0754 −0.1423 0.93690.8752 1 1 WCM10_Z1-1 7 76825823 97488205 0.0912 0.1189 1.1106 1.0612 11 WCM10_Z1-1 7 97488569 97823038 0.0366 0.0351 NA NA NA NA WCM10_Z1-1 797823249 102523911 −0.0744 −0.1407 1.0746 0.7396 1 1 WCM10_Z1-1 7102524111 158937416 0.0349 0.0325 1.0339 1.0117 1 1 WCM10_Z1-1 8 192852146279480 0.0286 0.0228 1.0207 1.0112 1 1 WCM10_Z1-1 9 117642 2032918−0.078 −0.1465 0.9577 0.8492 1 1 WCM10_Z1-1 9 2039500 125513005 0.03170.0276 1.0209 1.0177 1 1 WCM10_Z1-1 9 125513064 141016474 −0.0338−0.0754 0.9717 0.9264 1 1 WCM10_Z1-1 X 2700163 154509348 0.0164 0.0038NA NA NA NA WCM119 1 17465 119988184 −0.1644 −0.4482 0.9413 0.5246 1 1WCM119 1 119988585 152101126 0.1758 0.0826 1.1442 0.9736 1 1 WCM119 1152102620 153604233 0.505 0.5426 1.4722 1.441 1 1 WCM119 1 153606810156777073 0.1215 0.0023 1.0315 0.9717 1 1 WCM119 1 156777145 2025747340.3014 0.2631 1.2 1.2 1 1 WCM119 1 202696570 249214028 0.2205 0.14751.1077 1.1077 1 1 WCM119 10 226107 3827144 −0.366 −0.8031 0.6285 0.51771 1 WCM119 10 4702299 44865739 0.1071 −0.0193 0.9867 0.9867 1 1 WCM11910 44866751 46217168 −0.4747 −1.0121 NA NA NA NA WCM119 10 4621775560129301 0.2121 0.1354 1.1016 1.0952 1 1 WCM119 10 60130322 63816876−0.4221 −0.9092 NA NA NA NA WCM119 10 63817096 69905295 0.05 −0.1058 NANA NA NA WCM119 10 69908083 71851670 −0.4235 −0.9119 1.066 −0.003 1 0WCM119 10 71851726 89312053 0.14 0.0297 1.0208 1.0208 1 1 WCM119 1089419781 90122432 −1.515 NA NA NA NA NA WCM119 10 90332708 1354779130.0928 −0.0408 0.9721 0.9721 1 1 WCM119 11 193096 62066474 0.1506 0.04541.032 1.032 1 1 WCM119 11 62105609 76163008 −0.0245 −0.2213 0.85780.8578 1 1 WCM119 11 76164325 118771385 0.144 0.0357 1.025 1.025 1 1WCM119 11 118771708 122955468 −0.14 −0.4076 0.8249 0.6828 1 1 WCM119 11122968481 134605959 0.162 0.0622 1.044 1.044 1 1 WCM119 12 1484803407389 0.0951 −0.0373 0.9745 0.9745 1 1 WCM119 12 3409239 16757863−0.4211 −0.9073 1.046 0.0203 1 0 WCM119 12 18234097 111472030 0.1138−0.0092 0.9936 0.9936 1 1 WCM119 12 111511888 133810883 −0.5158 −1.09520.9666 −0.0305 1 0 WCM119 13 19041979 115089411 −0.1596 −0.4402 0.91040.5636 1 1 WCM119 14 19110188 68228217 −0.191 −0.493 0.903 0.518 1 1WCM119 14 68228977 70243006 −0.4891 −1.041 0.9586 0.0134 1 0 WCM119 1470245147 107283088 −0.1706 −0.4585 0.9254 0.53 1 1 WCM119 15 2008389664747160 0.308 0.2723 1.3489 1.0666 1 1 WCM119 15 64791668 80263484−0.5076 −1.0784 0.9315 0.0156 1 0 WCM119 15 80412697 102514186 0.0704−0.0746 0.9496 0.9496 1 1 WCM119 16 64429 34277581 0.1031 −0.0254 0.98260.9826 1 1 WCM119 16 34277902 90260461 −0.5102 −1.0839 0.9443 −7.00E−04 1 0 WCM119 17 131595 4585911 0.0534 −0.1006 0.9326 0.9326 1 1 WCM119 174586161 16537207 −0.5093 −1.082 0.9307 0.014 1 0 WCM119 17 1653798731618703 0.0372 −0.1253 0.9168 0.9168 1 1 WCM119 17 32201294 36248549−0.4898 −1.0424 0.9618 0.0092 1 0 WCM119 17 36339813 39341158 −0.1969−0.5029 0.8267 0.5846 1 1 WCM119 17 39341473 43186394 −0.4547 −0.97260.8633 0.1558 1 0 WCM119 17 43189953 63133674 −0.1774 −0.4701 0.9320.5118 1 1 WCM119 17 63149650 81187935 0.0787 −0.062 1.422 0.4938 1 0WCM119 18 47632 61602369 0.0886 −0.0471 0.9679 0.9679 1 1 WCM119 1861620715 78005197 −0.5129 −1.0894 0.906 0.034 1 0 WCM119 19 1049634095331 −0.1703 −0.4581 0.8317 0.6242 1 1 WCM119 19 4097321 46857970.3494 0.3302 1.3429 1.1714 1 1 WCM119 19 4689534 10394391 −0.0912−0.3277 0.9425 0.6511 1 1 WCM119 19 10394764 13319842 0.0597 −0.09090.9733 0.9046 1 1 WCM119 19 13321480 23317042 0.2858 0.2409 1.19681.1667 1 1 WCM119 19 23318731 58920263 0.085 −0.0525 0.9643 0.9643 1 1WCM119 19 58921455 59093696 −0.1978 −0.5045 NA NA NA NA WCM119 2 415958952612 −0.1616 −0.4436 0.7881 0.6825 1 1 WCM119 2 8953489 10583643−0.557 −1.1812 0.9264 −0.0444 1 0 WCM119 2 10583865 20518340 −0.1223−0.3784 0.9459 0.5926 1 1 WCM119 2 20525948 20649195 −1.3933 −5.0442 NANA NA NA WCM119 2 20699667 25945260 −0.1476 −0.4202 0.9866 0.508 1 1WCM119 2 25964713 26750645 −0.4629 −0.9888 1.0211 −0.0132 1 0 WCM119 226760649 216002860 −0.1507 −0.4254 0.9562 0.5331 1 1 WCM119 2 216177303218620823 −0.9022 −2.0448 0.5047 −0.02 1 0 WCM119 2 218667474 243052762−0.1472 −0.4195 0.8953 0.6001 1 1 WCM119 20 68406 348183 −0.3474 −0.7687NA NA NA NA WCM119 20 348244 34220224 −0.1449 −0.4158 0.9645 0.5347 1 1WCM119 20 34220601 47558574 −0.4609 −0.9847 1.0312 −0.0205 1 0 WCM119 2047567811 62934623 0.3016 0.2633 1.2205 1.1799 1 1 WCM119 21 959036934717604 −0.1604 −0.4414 0.9207 0.5521 1 1 WCM119 21 34721524 39823096−0.312 −0.7043 0.6868 0.5407 1 1 WCM119 21 39870310 41300922 −0.9834−2.3067 0.4286 −0.0243 0 0 WCM119 21 41301084 42870017 −0.4936 −1.05021.0028 −0.037 1 0 WCM119 21 43133055 48084177 0.0839 −0.0542 0.96310.9631 1 1 WCM119 22 16159043 51219129 0.0578 −0.0939 0.937 0.937 1 1WCM119 3 239531 1427204 0.2511 0.1916 NA NA NA NA WCM119 3 142745011059596 0.0215 −0.1496 0.9182 0.8848 1 1 WCM119 3 11059732 12653407−0.4855 −1.0338 0.9848 −0.0079 1 0 WCM119 3 12660127 154898748 0.32940.3023 1.2331 1.2331 1 1 WCM119 3 154983068 179132727 0.4988 0.53431.4482 1.4482 1 1 WCM119 3 179134323 197896656 0.3176 0.2858 1.23451.2037 1 1 WCM119 4 53375 190904455 −0.1776 −0.4703 0.9161 0.5275 1 1WCM119 5 90537 9066764 0.0846 −0.0531 0.9638 0.9638 1 1 WCM119 5 910842470800475 −0.1567 −0.4354 0.8541 0.6249 1 1 WCM119 5 70805422 1806878280.0774 −0.064 0.9566 0.9566 1 1 WCM119 6 203475 67859495 0.0762 −0.06590.9554 0.9554 1 1 WCM119 6 69345838 170892697 −0.1449 −0.4157 0.9360.5633 1 1 WCM119 7 193205 158937018 0.1294 0.0141 1.0098 1.0098 1 1WCM119 8 163438 18391899 −0.2683 −0.6263 0.6604 0.6353 1 1 WCM119 818392379 41836324 −0.6711 −1.4344 0.7193 0.0207 1 0 WCM119 8 41838344146279399 0.0494 −0.1067 0.9287 0.9287 1 1 WCM119 9 14878 971774790.0899 −0.0451 0.9692 0.9692 1 1 WCM119 9 97191424 99521494 −0.4851−1.0329 0.9509 0.0266 1 0 WCM119 9 99521523 141107525 0.0883 −0.04760.9676 0.9676 1 1 WCM119 X 2700202 9000969 −0.3646 −0.8004 NA NA NA NAWCM119 X 9622286 12712534 0.4274 0.4377 NA NA NA NA WCM119 X 1272015713774915 −0.4728 −1.0085 NA NA NA NA WCM119 X 13775867 20283620 0.57660.6375 NA NA NA NA WCM119 X 20590519 26236216 1.1069 1.3019 NA NA NA NAWCM119 X 27479248 43603422 −0.4495 −0.9624 NA NA NA NA WCM119 X 4360371557937046 1.0293 1.2083 NA NA NA NA WCM119 X 61998801 69176915 2.13952.4748 NA NA NA NA WCM119 X 69178468 73069575 0.802 0.9276 NA NA NA NAWCM119 X 73070031 75004943 0.4132 0.4183 NA NA NA NA WCM119 X 75393441101821867 −0.4297 −0.9239 NA NA NA NA WCM119 X 101822823 102613323 1.1341.3344 NA NA NA NA WCM119 X 102632519 119761006 0.5011 0.5372 NA NA NANA WCM119 X 120008890 132162272 −0.5008 −1.0647 NA NA NA NA WCM119 X132351105 134126297 0.5541 0.6079 NA NA NA NA WCM119 X 134155965135496525 −0.4315 −0.9273 NA NA NA NA WCM119 X 135498568 1377141380.5572 0.6119 NA NA NA NA WCM119 X 137714483 154493609 −0.4249 −0.9145NA NA NA NA WCM119_Z6_1 1 69594 120050152 −0.216 0.6223 2.0706 1.008 2 1WCM119_Z6_1 1 120056648 249212429 0.3725 1.3395 3.0454 2.0157 3 2WCM119_Z6_1 10 225960 468916 −0.7159 −0.0544 NA NA NA NA WCM119_Z6_1 10486884 44345143 0.1454 1.0701 2.1273 2.0717 2 2 WCM119_Z6_1 10 4486680847769286 −0.4853 0.2681 NA NA NA NA WCM119_Z6_1 10 48370587 602729760.1294 1.0508 2.1016 2.0416 2 2 WCM119_Z6_1 10 60380631 63450323 −0.64750.0434 NA NA NA NA WCM119_Z6_1 10 63519858 69905277 0.1094 1.0266 NA NANA NA WCM119_Z6_1 10 69908187 71718455 −0.557 0.17 2.2141 0.036 2 0WCM119_Z6_1 10 71835546 89481518 0.1524 1.0785 2.1449 2.0789 2 2WCM119_Z6_1 10 89487142 90356651 −1.7977 −2.1273 NA NA NA NA WCM119_Z6_110 90362375 135440086 0.1455 1.0702 2.1225 2.077 2 2 WCM119_Z6_1 11193112 71293558 0.101 1.0164 2.045 2.0009 2 2 WCM119_Z6_1 11 7129367775148030 −0.2198 0.6174 2.0385 1.0297 2 1 WCM119_Z6_1 11 75150397118851234 0.0994 1.0145 2.057 1.9835 2 2 WCM119_Z6_1 11 118867695122165645 −0.2548 0.5725 1.8435 1.1308 2 1 WCM119_Z6_1 11 122526799134856523 0.1099 1.0272 2.0947 1.9813 2 2 WCM119_Z6_1 12 148675 34093040.2077 1.1448 NA NA NA NA WCM119_Z6_1 12 3490591 17142459 −0.6653 0.01822.1009 −0.0755 2 0 WCM119_Z6_1 12 17826233 41946470 0.0821 0.9934 2.02961.9522 2 2 WCM119_Z6_1 12 41949551 68549144 0.0162 0.913 1.9177 1.8483 22 WCM119_Z6_1 12 68551734 111375170 0.1137 1.0318 2.0742 2.0149 2 2WCM119_Z6_1 12 111471998 133810703 −0.6621 0.0228 2.0285 0.0033 2 0WCM119_Z6_1 13 19600475 115089411 −0.2254 0.6102 2.0759 0.9771 2 1WCM119_Z6_1 14 19377697 68222802 −0.2316 0.6023 2.0301 1.0061 2 1WCM119_Z6_1 14 68228028 70175757 −0.6466 0.0447 NA NA NA NA WCM119_Z6_114 70177691 107283213 −0.2195 0.6178 2.0862 0.9829 2 1 WCM119_Z6_1 1520170018 45962168 0.5568 1.5527 3.011 2.8563 3 3 WCM119_Z6_1 15 4596588064747240 0.1306 1.0522 3.0721 1.0753 3 1 WCM119_Z6_1 15 6479182980260029 −1.2954 −0.9923 1.0707 −0.0654 1 0 WCM119_Z6_1 15 80263171102517639 −0.2203 0.6168 2.077 0.99 2 1 WCM119_Z6_1 16 66966 339655600.116 1.0346 2.0931 2.004 2 2 WCM119_Z6_1 16 34257013 90233596 −0.65920.0268 2.0666 −0.0291 2 0 WCM119_Z6_1 17 131595 4586185 0.0892 1.00212.0539 1.9518 2 2 WCM119_Z6_1 17 4594269 16538031 −0.6547 0.0333 2.0745−0.0278 2 0 WCM119_Z6_1 17 16550679 31618443 0.0953 1.0095 2.0548 1.97172 2 WCM119_Z6_1 17 31618866 36353758 −0.6864 −0.0119 1.9889 −0.0053 2 0WCM119_Z6_1 17 36357230 39086290 −0.2534 0.5743 1.9971 0.9808 2 1WCM119_Z6_1 17 39114868 41020861 −0.6876 −0.0136 2.0181 −0.0369 2 0WCM119_Z6_1 17 41031597 42287770 −0.3609 0.4343 1.8531 0.8493 2 1WCM119_Z6_1 17 42288288 43182993 −0.6686 0.0136 2.0434 −0.0245 2 0WCM119_Z6_1 17 43190066 63746821 −0.2422 0.5887 2.0276 0.9802 2 1WCM119_Z6_1 17 63822329 81083567 0.1003 1.0156 3.0533 0.9902 3 1WCM119_Z6_1 18 48202 61602462 0.1225 1.0424 2.092 2.0273 2 2 WCM119_Z6_118 61620752 78005214 −0.6955 −0.025 2.0625 −0.0969 2 0 WCM119_Z6_1 19281468 3478866 −0.2648 0.5596 2.0104 0.9374 2 1 WCM119_Z6_1 19 34804483700307 0.3668 1.3328 NA NA NA NA WCM119_Z6_1 19 3728440 4090617 −0.30130.5122 1.9048 0.9477 2 1 WCM119_Z6_1 19 4094487 4685563 0.3231 1.28152.5539 2.308 3 2 WCM119_Z6_1 19 4688845 10341096 −0.2708 0.5519 2.00210.9298 2 1 WCM119_Z6_1 19 10362984 11687196 0.3768 1.3444 3.0081 2.07033 2 WCM119_Z6_1 19 11687534 12719976 −0.3225 0.4847 1.9751 0.8235 2 1WCM119_Z6_1 19 12720757 20308715 0.3368 1.2975 2.8189 2.0973 3 2WCM119_Z6_1 19 20308825 59083988 0.0557 0.9613 1.9756 1.9186 2 2WCM119_Z6_1 2 41620 8926125 −0.2608 0.5648 1.855 1.1033 2 1 WCM119_Z6_12 8926425 10564692 −0.6761 0.0028 NA NA NA NA WCM119_Z6_1 2 1056688725803648 −0.2543 0.5731 2.0358 0.9396 2 1 WCM119_Z6_1 2 2581908126804247 −0.6788 −0.001 2.043 −0.0445 2 0 WCM119_Z6_1 2 26805757216002898 −0.2275 0.6076 2.0372 1.0103 2 1 WCM119_Z6_1 2 216176870218620794 −1.2937 −0.9891 NA NA NA NA WCM119_Z6_1 2 218669179 242946607−0.2221 0.6144 2.0365 1.0254 2 1 WCM119_Z6_1 20 68363 34858532 −0.21650.6217 2.0561 1.0213 2 1 WCM119_Z6_1 20 35060162 47557736 −0.6738 0.00612.023 −0.0145 2 0 WCM119_Z6_1 20 47558464 62904866 0.4289 1.4051 3.20222.0945 3 2 WCM119_Z6_1 21 9826205 39822803 −0.2317 0.6022 2.0339 1.00222 1 WCM119_Z6_1 21 39947620 43133720 −1.2677 −0.9415 0.9621 0.0793 1 0WCM119_Z6_1 21 43134230 48084204 −0.2078 0.6328 1.9879 1.1131 2 1WCM119_Z6_1 22 16287478 51215134 0.1015 1.017 2.0385 2.0091 2 2WCM119_Z6_1 3 239436 10861246 0.0997 1.0149 2.1187 1.9228 2 2WCM119_Z6_1 3 10861450 12653531 −0.7027 −0.0354 NA NA NA NA WCM119_Z6_13 12660201 197894720 0.3793 1.3473 3.0112 2.0776 3 2 WCM119_Z6_1 4 593971087555 −0.4523 0.3126 1.3104 1.1735 1 1 WCM119_Z6_1 4 1090625 87622684−0.3314 0.4731 1.7678 1.0084 2 1 WCM119_Z6_1 4 87622942 190426502−0.4853 0.2681 1.4361 0.9724 1 1 WCM119_Z6_1 5 140657 180687804 −0.22460.6112 2.042 1.0131 2 1 WCM119_Z6_1 6 203515 65612302 0.3721 1.33893.0237 2.0356 3 2 WCM119_Z6_1 6 65622463 170893411 −0.2291 0.6055 2.02071.0223 2 1 WCM119_Z6_1 7 193205 43436424 0.0238 0.9224 1.9324 1.858 2 2WCM119_Z6_1 7 43447302 128506750 0.1906 1.1244 2.3027 2.0575 2 2WCM119_Z6_1 7 128508812 158937400 0.0225 0.9207 2.1252 1.6609 2 2WCM119_Z6_1 8 190908 19297347 0.0976 1.0123 2.0954 1.9389 2 2WCM119_Z6_1 8 19315321 41906095 −0.6871 −0.0129 2.0416 −0.0595 2 0WCM119_Z6_1 8 41906261 146279514 0.1661 1.095 2.1848 2.0874 2 2WCM119_Z6_1 9 17055 97177479 0.1027 1.0185 2.0528 1.9988 2 2 WCM119_Z6_19 97203361 99417036 −0.6616 0.0235 NA NA NA NA WCM119_Z6_1 9 99521302141111414 0.0999 1.0151 2.0553 1.9867 2 2 WCM119_Z6_1 X 2707700 9001007−0.582 0.1354 NA NA NA NA WCM119_Z6_1 X 9621715 11793148 0.591 1.5918 NANA NA NA WCM119_Z6_1 X 12632953 13769388 −0.5947 0.1177 NA NA NA NAWCM119_Z6_1 X 13771497 20194447 0.5616 1.5582 NA NA NA NA WCM119_Z6_1 X20206041 25031901 1.2151 2.2862 NA NA NA NA WCM119_Z6_1 X 2503368926236115 0.6384 1.6459 NA NA NA NA WCM119_Z6_1 X 27478926 28807508−0.6034 0.1055 NA NA NA NA WCM119_Z6_1 X 29301057 30577652 0.4976 1.4847NA NA NA NA WCM119_Z6_1 X 30578153 42637311 −0.7136 −0.051 NA NA NA NAWCM119_Z6_1 X 43542795 44037679 0.4331 1.41 NA NA NA NA WCM119_Z6_1 X44088925 57936447 1.2033 2.2734 NA NA NA NA WCM119_Z6_1 X 6289836069176971 2.2368 3.3709 NA NA NA NA WCM119_Z6_1 X 69242767 730949141.0379 2.0924 NA NA NA NA WCM119_Z6_1 X 73095472 75396725 0.4623 1.4439NA NA NA NA WCM119_Z6_1 X 75397840 101581385 −0.6649 0.0187 NA NA NA NAWCM119_Z6_1 X 101857242 102632712 1.2928 2.3705 NA NA NA NA WCM119_Z6_1X 102831404 107627026 0.6078 1.611 NA NA NA NA WCM119_Z6_1 X 107683386107979388 −0.7419 −0.0921 NA NA NA NA WCM119_Z6_1 X 108619152 1116985690.5926 1.5937 NA NA NA NA WCM119_Z6_1 X 111698889 117480524 −0.6928−0.0211 NA NA NA NA WCM119_Z6_1 X 117526683 119760973 0.5799 1.5791 NANA NA NA WCM119_Z6_1 X 120008749 132162173 −0.6683 0.0139 NA NA NA NAWCM119_Z6_1 X 132351220 134186126 0.5358 1.5286 NA NA NA NA WCM119_Z6_1X 134303518 135496346 −0.7627 −0.1224 NA NA NA NA WCM119_Z6_1 X135519177 136659281 0.5855 1.5856 NA NA NA NA WCM119_Z6_1 X 137715128154509348 −0.674 0.0058 NA NA NA NA WCM12 1 14930 249213967 0.01690.0963 1.0691 1.0691 1 1 WCM12 10 225936 135439008 0.0148 0.0765 1.05441.0544 1 1 WCM12 11 193096 62327920 0.0362 0.2682 1.2655 1.1431 1 1WCM12 11 62334460 65827316 −0.1283 −3.254 0.2232 −0.0135 0 0 WCM12 1165828095 134605906 0.0236 0.1578 1.1156 1.1156 1 1 WCM12 12 148560133810703 −0.0025 −0.098 0.9343 0.9343 1 1 WCM12 13 19041937 115089411−0.0097 −0.1763 0.885 0.885 1 1 WCM12 14 19110387 107283270 −2.00E−04−0.0732 0.9505 0.9505 1 1 WCM12 15 20083896 102516308 0.0266 0.18471.1771 1.096 1 1 WCM12 16 66882 90260461 −0.0016 −0.0885 0.9405 0.9405 11 WCM12 17 131595 81187813 −0.0095 −0.1737 0.8866 0.8866 1 1 WCM12 1847824 78005110 0.0052 −0.0178 0.9877 0.9877 1 1 WCM12 19 104963 59093696−0.0332 −0.4638 0.7251 0.7251 1 1 WCM12 2 41602 243052710 −0.004 −0.11360.9243 0.9243 1 1 WCM12 20 68319 62934618 0.0208 0.132 1.0958 1.0958 1 1WCM12 21 9590271 48084253 −0.0113 −0.194 0.8742 0.8742 1 1 WCM12 2216159046 51223730 0.0405 0.3042 1.2757 1.1938 1 1 WCM12 3 239390197896801 0.0094 0.0237 1.0166 1.0166 1 1 WCM12 4 53446 190874234−0.0037 −0.1112 0.9258 0.9258 1 1 WCM12 5 90684 180687812 −0.0115−0.1966 0.8726 0.8726 1 1 WCM12 6 203369 170892877 −0.006 −0.136 0.910.91 1 1 WCM12 7 195702 158937158 0.0022 −0.0489 1.0065 0.9268 1 1 WCM128 163432 146279453 −0.0037 −0.1108 0.9261 0.9261 1 1 WCM12 9 116800141107539 0.0204 0.129 1.0935 1.0935 1 1 WCM12 X 2700141 154507335−0.0248 −0.3548 NA NA NA NA WCM121 1 14907 249213964 0.0191 NA NA NA NANA WCM121 10 226116 135438973 0.0155 NA NA NA NA NA WCM121 11 193096134605916 0.0189 NA NA NA NA NA WCM121 12 148580 133810905 0.0052 NA NANA NA NA WCM121 13 19041979 115089411 −0.0043 NA NA NA NA NA WCM121 1419110178 107283266 0.0068 NA NA NA NA NA WCM121 15 20083896 1025141880.0233 NA NA NA NA NA WCM121 16 66921 90260461 0.015 NA NA NA NA NAWCM121 17 131595 81187934 0.0029 NA NA NA NA NA WCM121 18 47654 780052030.0103 NA NA NA NA NA WCM121 19 105021 59093645 0.0047 NA NA NA NA NAWCM121 2 41614 243037022 0.0044 NA NA NA NA NA WCM121 20 68311 629346180.0353 NA NA NA NA NA WCM121 21 9590271 48084114 0.0055 NA NA NA NA NAWCM121 22 16159043 51219089 0.0517 NA NA NA NA NA WCM121 3 239495197896720 0.016 NA NA NA NA NA WCM121 4 53397 190904468 0.0033 NA NA NANA NA WCM121 5 90696 180687861 0.0046 NA NA NA NA NA WCM121 6 203510170892854  1.00E−04 NA NA NA NA NA WCM121 7 193253 158937142 0.0191 NANA NA NA NA WCM121 8 163491 146279507 0.0164 NA NA NA NA NA WCM121 914893 141107468 0.0216 NA NA NA NA NA WCM121 X 2700122 154493585 −0.0838NA NA NA NA NA WCM121_Z1_1 1 721439 23696165 −0.4129 0.0473 1.24580.8209 1 1 WCM121_Z1_1 1 23697698 28835161 −0.1586 0.5836 1.9881 1.00912 1 WCM121_Z1_1 1 28835457 75184893 0.0727 0.9995 2.0365 1.9622 2 2WCM121_Z1_1 1 75188910 120458366 −0.1291 0.6399 2.0667 1.0497 2 1WCM121_Z1_1 1 120458537 151735425 0.0966 1.0397 2.9941 1.1176 3 1WCM121_Z1_1 1 151735817 179562992 −0.142 0.6155 2.0273 1.0369 2 1WCM121_Z1_1 1 179587734 205686457 0.0899 1.0285 2.1015 1.9784 2 2WCM121_Z1_1 1 205687444 249150528 −0.1306 0.6371 2.0456 1.0649 2 1WCM121_Z1_1 1 249150750 249212550 −0.2457 0.4113 NA NA NA NA WCM121_Z1_110 225958 294540 −0.6799 −0.677 NA NA NA NA WCM121_Z1_1 10 29495389624305 −0.3988 0.08 2.0419 0.0721 2 0 WCM121_Z1_1 10 89653806 97471746−0.7427 −0.8891 1.0279 0.052 1 0 WCM121_Z1_1 10 97515513 1065818580.3725 1.4752 5.5972 −0.0369 6 0 WCM121_Z1_1 10 106602595 135381734−0.4011 0.0747 2.0924 0.0138 2 0 WCM121_Z1_1 11 193112 58891926 −0.12530.6471 2.0818 1.0503 2 1 WCM121_Z1_1 11 58892177 108061213 0.0904 1.02942.0412 2.0412 2 2 WCM121_Z1_1 11 108062894 113651182 −0.0214 0.8367 NANA NA NA WCM121_Z1_1 11 113669963 114578268 −0.6919 −0.716 NA NA NA NAWCM121_Z1_1 11 115040326 134856603 −0.1389 0.6213 2.0054 1.0712 2 1WCM121_Z1_1 12 148675 38714888 0.2702 1.3193 2.8985 2.0922 3 2WCM121_Z1_1 12 39047733 133810751 −0.1415 0.6165 2.0781 0.9882 2 1WCM121_Z1_1 13 19600515 37622053 0.0724 0.9991 2.0731 1.9244 2 2WCM121_Z1_1 13 37622734 88329447 −0.4179 0.0357 2.0356 0.0145 2 0WCM121_Z1_1 13 88329761 115089411 0.0915 1.0313 2.1055 1.9822 2 2WCM121_Z1_1 14 19377726 39545199 0.0729 1 2.071 1.929 2 2 WCM121_Z1_1 1439555104 50052722 −0.3386 0.2153 NA NA NA NA WCM121_Z1_1 14 5005304568301899 0.092 1.0321 2.117 1.9731 2 2 WCM121_Z1_1 14 68331832 69117512−0.3841 0.1137 NA NA NA NA WCM121_Z1_1 14 69256333 69989094 −0.4545−0.0519 1.9546 −0.0252 2 0 WCM121_Z1_1 14 69991014 101198385 −0.14740.6051 2.0405 1.0016 2 1 WCM121_Z1_1 14 101200705 107283047 0.08311.0171 3.042 1.0059 3 1 WCM121_Z1_1 15 20170019 35830632 0.5165 1.68584.5873 1.8469 5 2 WCM121_Z1_1 15 35834693 102514200 −0.1419 0.61562.0479 1.0166 2 1 WCM121_Z1_1 16 67604 49193569 0.0799 1.0118 2.04021.9926 2 2 WCM121_Z1_1 16 49313348 90233622 −0.414 0.0447 2.0158 0.04722 0 WCM121_Z1_1 17 131595 16326854 −0.4139 0.045 1.0558 1.0076 1 1WCM121_Z1_1 17 16329476 20268662 −0.1324 0.6336 2.0382 1.0646 2 1WCM121_Z1_1 17 20356346 33968991 0.077 1.0069 2.0808 1.9384 2 2WCM121_Z1_1 17 33977634 80914613 −0.1537 0.5931 2.0402 0.9769 2 1WCM121_Z1_1 17 80915101 81083520 −0.444 −0.0264 NA NA NA NA WCM121_Z1_118 48200 214889 −0.1475 0.605 NA NA NA NA WCM121_Z1_1 18 215504 425330550.0558 0.971 2.0203 1.9 2 2 WCM121_Z1_1 18 42533280 78005215 −0.14190.6156 2.0536 1.0107 2 1 WCM121_Z1_1 19 281503 59083929 0.0537 0.96741.9853 1.9252 2 2 WCM121_Z1_1 2 41612 286139 0.0848 1.02 NA NA NA NAWCM121_Z1_1 2 287677 3464074 0.103 1.0504 NA NA NA NA WCM121_Z1_1 23466632 37595798 −0.1308 0.6367 2.0128 1.0968 2 1 WCM121_Z1_1 2 3759685344559625 −0.7006 −0.7445 0.943 0.2508 1 0 WCM121_Z1_1 2 4456565545715451 −0.0423 0.7994 NA NA NA NA WCM121_Z1_1 2 45773933 1752137460.0766 1.0062 3.0458 0.9714 3 1 WCM121_Z1_1 2 175215421 242946597 0.27671.3293 2.9022 2.1235 3 2 WCM121_Z1_1 20 68373 62904866 0.0826 1.01622.0737 1.9716 2 2 WCM121_Z1_1 21 9907280 39818748 0.0804 1.0125 2.07861.9563 2 2 WCM121_Z1_1 21 39822803 42866328 −0.3799 0.1234 NA NA NA NAWCM121_Z1_1 21 42870082 48084281 0.085 1.0203 2.117 1.9397 2 2WCM121_Z1_1 22 17063431 28490068 0.0862 1.0223 2.113 1.9493 2 2WCM121_Z1_1 22 28492368 30421766 −0.4684 −0.0859 1.969 −0.0846 2 0WCM121_Z1_1 22 30494916 46403039 0.0771 1.007 2.0911 1.9283 2 2WCM121_Z1_1 22 46447714 51219138 −0.1609 0.5794 1.8967 1.0917 2 1WCM121_Z1_1 3 239398 119120818 0.0872 1.024 2.0677 1.9994 2 2WCM121_Z1_1 3 119121158 197444907 0.0814 1.0143 3.064 0.9759 3 1WCM121_Z1_1 3 197463575 197894713 0.0509 0.9626 NA NA NA NA WCM121_Z1_14 59331 44724157 −0.1309 0.6366 2.086 1.0233 2 1 WCM121_Z1_1 4 4605357352729629 0.5978 1.8005 4.9573 2.0095 5 2 WCM121_Z1_1 4 52740498 529382430.1072 1.0575 NA NA NA NA WCM121_Z1_1 4 52943087 148461073 −0.14370.6122 2.0377 1.0194 2 1 WCM121_Z1_1 4 148461553 167022017 0.23 1.25642.5058 2.2721 3 2 WCM121_Z1_1 4 167656188 189013084 −0.4013 0.07432.0945 0.0112 2 0 WCM121_Z1_1 4 189014004 190426502 −0.3693 0.1473 NA NANA NA WCM121_Z1_1 5 140595 2751474 0.0569 0.9728 2.1532 1.772 2 2WCM121_Z1_1 5 2752397 55218257 −0.1228 0.6518 2.0169 1.1254 2 1WCM121_Z1_1 5 55237009 59901547 −0.6794 −0.6754 NA NA NA NA WCM121_Z1_15 59934677 125885968 −0.1271 0.6437 2.1686 0.956 2 1 WCM121_Z1_1 5125887715 180687768 0.0826 1.0162 2.0227 2.0227 2 2 WCM121_Z1_1 6 2035165771586 0.2182 1.2377 3.0873 1.6291 3 2 WCM121_Z1_1 6 5999241 12296197−0.1042 0.6865 3.0747 0.1441 3 0 WCM121_Z1_1 6 12933969 16307085 0.20041.2094 NA NA NA NA WCM121_Z1_1 6 16326782 55929378 0.2803 1.3349 3.01052.0346 3 2 WCM121_Z1_1 6 55933860 117630024 0.085 1.0203 2.1033 1.9533 22 WCM121_Z1_1 6 117631388 159414899 −0.146 0.6079 1.9831 1.0651 2 1WCM121_Z1_1 6 159420492 170893450 −0.6981 −0.7362 1.1947 0.0059 1 0WCM121_Z1_1 7 193254 158937416 0.4479 1.5866 4.0031 2.0038 4 2WCM121_Z1_1 8 190908 31012272 −0.4181 0.0352 2.0327 0.0167 2 0WCM121_Z1_1 8 31015037 65291808 −0.1467 0.6065 1.8768 1.1683 2 1WCM121_Z1_1 8 65489051 146279479 0.2904 1.3505 3.0178 2.0823 3 2WCM121_Z1_1 9 17075 3275569 −0.1359 0.627 2.0387 1.0499 2 1 WCM121_Z1_19 3277387 71534437 0.0979 1.042 2.0935 2.0247 2 2 WCM121_Z1_1 9 71538291141111414 −0.1474 0.6052 1.9972 1.0453 2 1 WCM121_Z1_1 X 270770965486401 0.0335 0.9326 NA NA NA NA WCM121_Z1_1 X 65817849 687259083.9537 5.5976 NA NA NA NA WCM121_Z1_1 X 68748854 70838300 −0.4579 −0.06NA NA NA NA WCM121_Z1_1 X 71131171 154509348 0.0344 0.9342 NA NA NA NAWCM124 1 14930 249213964 0.0579 NA NA NA NA NA WCM124 10 226060135438967 0.0294 NA NA NA NA NA WCM124 11 193096 65211940 0.0399 NA NANA NA NA WCM124 11 65233857 65404406 −0.4568 NA NA NA NA NA WCM124 1165408667 134605954 0.0254 NA NA NA NA NA WCM124 12 148560 1338108960.0305 NA NA NA NA NA WCM124 13 19041992 115089411 −0.0095 NA NA NA NANA WCM124 14 19110387 107283270 0.0305 NA NA NA NA NA WCM124 15 20083928102516226 0.0489 NA NA NA NA NA WCM124 16 66921 90168701 0.012 NA NA NANA NA WCM124 17 131595 81052551 0.0202 NA NA NA NA NA WCM124 18 4773778005215 0.0216 NA NA NA NA NA WCM124 19 105080 59093645 −0.0014 NA NANA NA NA WCM124 2 41623 243037022 0.027 NA NA NA NA NA WCM124 20 6834262934623 0.0433 NA NA NA NA NA WCM124 21 9590326 48084149 −0.0157 NA NANA NA NA WCM124 22 16159060 51219089 0.0456 NA NA NA NA NA WCM124 3239443 197896800 0.0345 NA NA NA NA NA WCM124 4 53336 190878508 0.0022NA NA NA NA NA WCM124 5 90684 180687800 0.0415 NA NA NA NA NA WCM124 6203509 26108168 0.01 NA NA NA NA NA WCM124 6 26123684 26368372 −0.9642NA NA NA NA NA WCM124 6 26370569 41903720 0.0308 NA NA NA NA NA WCM124 641904276 42018312 −1.0896 NA NA NA NA NA WCM124 6 42019208 1708928480.0203 NA NA NA NA NA WCM124 7 193222 158937142 0.0379 NA NA NA NA NAWCM124 8 163470 146279527 0.0388 NA NA NA NA NA WCM124 9 14876 1411075730.0523 NA NA NA NA NA WCM124 X 2700147 154509348 0.021 NA NA NA NA NAWCM124_X1_3 1 69640 145115810 −0.1981 0.7647 2.2458 1.1522 2 1WCM124_X1_3 1 145209347 167298535 0.4452 1.7522 5.4341 1.3033 5 1WCM124_X1_3 1 167301765 167409963 −0.8247 −0.6169 NA NA NA NAWCM124_X1_3 1 167487701 176564156 0.4247 1.7239 5.4997 1.1068 5 1WCM124_X1_3 1 176564418 177937094 −0.7708 −0.4633 NA NA NA NAWCM124_X1_3 1 178062358 182026359 0.4069 1.6991 5.5612 0.9329 6 1WCM124_X1_3 1 182026496 185278606 1.0345 2.5136 10.0471 1.3739 10  1WCM124_X1_3 1 185703961 209602652 0.4915 1.8156 5.1689 1.8714 5 2WCM124_X1_3 1 209603818 210761383 −0.7666 −0.4519 1.3583 0.1039 1 0WCM124_X1_3 1 210796944 247020995 0.3865 1.6707 5.0821 1.2853 5 1WCM124_X1_3 1 247024353 248309356 −0.8213 −0.607 1.2238 0.0894 1 0WCM124_X1_3 1 248343317 248525792 0.4331 1.7355 5.323 1.337 5 1WCM124_X1_3 1 248551203 248551819 −0.873 −0.7646 NA NA NA NA WCM124_X1_31 248569369 249212378 0.3799 1.6614 NA NA NA NA WCM124_X1_3 10 22595281932615 −0.2164 0.7326 2.1047 1.2185 2 1 WCM124_X1_3 10 8201259982013316 −1.3894 −5.1259 NA NA NA NA WCM124_X1_3 10 82033594 135440068−0.2112 0.7416 2.1668 1.1773 2 1 WCM124_X1_3 11 193114 100211895 0.15461.3345 3.1101 1.9338 3 2 WCM124_X1_3 11 100221537 123524497 −0.28530.6085 3.0436 0.0057 3 0 WCM124_X1_3 11 123596714 130784841 −0.54740.084 2.1796 −0.0597 2 0 WCM124_X1_3 11 130785304 134856562 −0.01911.0646 NA NA NA NA WCM124_X1_3 12 148675 133810703 0.1452 1.3203 2.92322.0712 3 2 WCM124_X1_3 13 19600515 19997239 −0.5089 0.1675 NA NA NA NAWCM124_X1_3 13 20012235 20413092 0.1498 1.3273 NA NA NA NA WCM124_X1_313 20425532 21751155 0.8788 2.3208 NA NA NA NA WCM124_X1_3 13 2194926736167486 0.3067 1.5577 3.5468 2.3408 4 2 WCM124_X1_3 13 36202341108518940 −0.5444 0.0907 2.056 0.0737 2 0 WCM124_X1_3 13 108861007115089411 −0.2747 0.6279 3.0557 0.0348 3 0 WCM124_X1_3 14 19377711107283063 −0.1934 0.7729 2.1648 1.2525 2 1 WCM124_X1_3 15 20170150102517639 −0.2129 0.7387 2.1069 1.2304 2 1 WCM124_X1_3 16 66921 507019480.0371 1.1539 2.2775 2.1726 2 2 WCM124_X1_3 16 50703016 87799431 −0.55140.0751 2.1188 −0.012 2 0 WCM124_X1_3 16 87868141 90162138 0.0705 1.2062.3715 2.2426 2 2 WCM124_X1_3 17 131595 81083455 0.0284 1.1401 2.23532.1727 2 2 WCM124_X1_3 18 48206 357487 0.1171 1.2778 NA NA NA NAWCM124_X1_3 18 480729 3742361 0.5275 1.8645 3.9804 3.3023 4 3WCM124_X1_3 18 3814138 78005194 0.1681 1.3548 3.1551 1.9601 3 2WCM124_X1_3 19 281498 59083953 −0.0052 1.0869 2.1921 2.0562 2 2WCM124_X1_3 2 41614 116593753 −0.2054 0.7519 2.1275 1.2405 2 1WCM124_X1_3 2 116594257 158400969 −0.5277 0.127 2.1727 0.0113 2 0WCM124_X1_3 2 158406868 164468038 −0.1773 0.8009 2.0467 1.4377 2 1WCM124_X1_3 2 164468200 185731121 0.1603 1.3431 3.8855 1.1883 4 1WCM124_X1_3 2 185798364 198675044 0.582 1.9375 3.8815 3.7794 4 4WCM124_X1_3 2 198948701 242946604 0.1656 1.3511 3.9085 1.1936 4 1WCM124_X1_3 20 68375 62904759 −0.0028 1.0906 2.1671 2.0922 2 2WCM124_X1_3 21 9826225 48084214 −0.2059 0.751 2.1027 1.2633 2 1WCM124_X1_3 22 16287459 51215124 −0.2044 0.7536 2.1327 1.2392 2 1WCM124_X1_3 3 239349 54880447 −0.1897 0.7793 2.1736 1.259 2 1WCM124_X1_3 3 54905607 142756978 0.1506 1.3286 3.8549 1.1681 4 1WCM124_X1_3 3 142757744 170943409 −0.2674 0.6412 1.6587 1.4605 2 1WCM124_X1_3 3 170946002 197896720 0.2392 1.46 4.3244 1.1778 4 1WCM124_X1_3 4 59327 135815 −0.548 0.0827 NA NA NA NA WCM124_X1_3 4154907 115898402 −0.2291 0.7101 2.0693 1.2025 2 1 WCM124_X1_3 4115997246 138453414 −0.5202 0.1431 1.922 0.2866 2 0 WCM124_X1_3 4139100420 183270997 −0.2418 0.6873 2.0889 1.1317 2 1 WCM124_X1_3 4183370160 190426502 −0.5168 0.1505 1.8652 0.3546 2 0 WCM124_X1_3 5140477 45695899 0.4989 1.8257 4.1084 2.9811 4 3 WCM124_X1_3 5 4969814285915201 −0.0966 0.9377 2.754 1.077 3 1 WCM124_X1_3 5 85916329 109103398−0.3766 0.4364 2.8106 −0.1042 3 0 WCM124_X1_3 5 109110590 166802458−0.0783 0.9681 2.7344 1.1781 3 1 WCM124_X1_3 5 167182180 1806878080.1596 1.342 2.615 2.4551 3 2 WCM124_X1_3 6 203515 79912064 −0.02821.0499 2.1105 2.0302 2 2 WCM124_X1_3 6 79913340 88773931 −0.5345 0.11222.1918 −0.03 2 0 WCM124_X1_3 6 88853635 123384862 −0.0345 1.0398 2.08582.0259 2 2 WCM124_X1_3 6 123539855 128403745 −0.4873 0.2131 NA NA NA NAWCM124_X1_3 6 128404866 170893450 −0.0228 1.0586 2.1098 2.0561 2 2WCM124_X1_3 7 193222 38765896 0.0483 1.1715 3.2994 1.2054 3 1WCM124_X1_3 7 38766569 45956969 0.2212 1.4336 2.9954 2.4072 3 2WCM124_X1_3 7 45960865 65842221 0.0668 1.2003 3.4298 1.166 3 1WCM124_X1_3 7 65842545 78131080 −0.1885 0.7814 3.1787 0.2589 3 0WCM124_X1_3 7 78150885 158937018 0.0514 1.1763 3.2702 1.2496 3 1WCM124_X1_3 8 190907 81582832 0.3661 1.6421 4.2198 2.0228 4 2WCM124_X1_3 8 81605315 94811977 −0.255 0.6636 2.4268 0.7413 2 1WCM124_X1_3 8 94815859 109491237 0.4152 1.7107 4.4735 2.0732 4 2WCM124_X1_3 8 109498828 114388973 −0.5146 0.1551 NA NA NA NA WCM124_X1_38 114448950 132051970 0.4148 1.7102 3.581 2.9629 4 3 WCM124_X1_3 8132052217 134538157 −0.4428 0.305 NA NA NA NA WCM124_X1_3 8 135490959146279424 0.5091 1.8396 4.3602 2.7979 4 3 WCM124_X1_3 9 17079 17330665−0.5536 0.0703 1.9581 0.1418 2 0 WCM124_X1_3 9 17332618 24543733 0.10441.2583 3.0811 1.7031 3 2 WCM124_X1_3 9 24544240 90582224 0.3881 1.6734.2462 2.1314 4 2 WCM124_X1_3 9 90582449 141111414 0.2256 1.4401 4.32381.103 4 1 WCM124_X1_3 X 2707694 57936541 −0.0736 0.9759 NA NA NA NAWCM124_X1_3 X 62898360 63445548 3.6159 5.3407 NA NA NA NA WCM124_X1_3 X63488455 63615223 0.092 1.2392 NA NA NA NA WCM124_X1_3 X 6413768569397492 3.2063 4.9161 NA NA NA NA WCM124_X1_3 X 69419191 83599274−0.1259 0.8887 NA NA NA NA WCM124_X1_3 X 83616567 89177098 −1.2638−2.7663 NA NA NA NA WCM124_X1_3 X 89177431 154509348 −0.0992 0.9334 NANA NA NA WCM12_Z10_1 1 721450 3775357 −0.1157 −0.0915 0.9647 0.9124 1 1WCM12_Z10_1 1 3776990 29863127 −0.7405 −0.9411 1.0558 −0.0141 1 0WCM12_Z10_1 1 31186459 145748533 −0.0467 −0.0046 1.0043 0.9894 1 1WCM12_Z10_1 1 146398489 166039898 0.4347 0.576 1.992 0.9894 2 1WCM12_Z10_1 1 166124000 185183757 1.0716 1.2968 3.8859 1.0276 4 1WCM12_Z10_1 1 185191034 249212344 0.4583 0.6035 2.0679 0.9709 2 1WCM12_Z10_1 10 225979 8006038 −0.0385 0.0056 1.0377 0.97 1 1 WCM12_Z10_110 8006262 8007471 −1.677 −2.7108 NA NA NA NA WCM12_Z10_1 10 805128158118353 −0.0613 −0.0229 1.0065 0.962 1 1 WCM12_Z10_1 10 58118630104309801 −0.6833 −0.8574 1.1061 −0.0022 1 0 WCM12_Z10_1 10 104352421125426022 −0.0513 −0.0104 0.9928 0.9928 1 1 WCM12_Z10_1 10 125426412135381660 −0.6597 −0.8231 1.1718 −0.0413 1 0 WCM12_Z10_1 11 19311295826599 −0.0585 −0.0194 1.0435 0.9297 1 1 WCM12_Z10_1 11 96074691109963934 −0.7767 −0.9951 0.9527 0.0507 1 0 WCM12_Z10_1 11 110001831113860464 −0.1591 −0.1467 NA NA NA NA WCM12_Z10_1 11 113934214 117152688−0.7062 −0.8908 1.0508 0.0278 1 0 WCM12_Z10_1 11 117153121 134856592−0.0922 −0.0618 0.9726 0.9436 1 1 WCM12_Z10_1 12 148644 114839669−0.0362 0.0085 1.0159 0.9958 1 1 WCM12_Z10_1 12 114841600 118852193−0.6874 −0.8632 NA NA NA NA WCM12_Z10_1 12 119419695 133810703 0.00860.0642 1.0571 1.0338 1 1 WCM12_Z10_1 13 19600515 47470924 −0.0739−0.0387 0.9919 0.9552 1 1 WCM12_Z10_1 13 48517532 92560249 −0.7086−0.8942 1.1054 −0.0293 1 0 WCM12_Z10_1 13 92797222 115089411 −0.01270.0378 1.0495 1.0036 1 1 WCM12_Z10_1 14 19377701 65878993 −0.0324 0.01331.0256 0.9929 1 1 WCM12_Z10_1 14 65937853 107283034 −0.7459 −0.94921.044 −0.0081 1 0 WCM12_Z10_1 15 20170150 36905707 −0.1447 −0.1283 1.0850.7448 1 1 WCM12_Z10_1 15 36906129 66190347 −0.7526 −0.9592 1.02650.0022 1 0 WCM12_Z10_1 15 66191192 102517660 −0.0476 −0.0058 1.00350.9885 1 1 WCM12_Z10_1 16 67604 74385987 −0.0857 −0.0536 1.0436 0.8834 11 WCM12_Z10_1 16 74394547 90233626 −0.7862 −1.0093 0.9889 0.0047 1 0WCM12_Z10_1 17 131595 13503897 −0.7724 −0.9887 1.0181 −0.0102 1 0WCM12_Z10_1 17 13504330 81083561 0.016 0.0734 1.0639 1.0404 1 1WCM12_Z10_1 18 48204 78005164 −0.0473 −0.0054 1.0037 0.9888 1 1WCM12_Z10_1 19 281430 59083953 −0.0694 −0.0331 0.9859 0.9687 1 1WCM12_Z10_1 2 41615 63849759 0.0039 0.0584 1.0543 1.0284 1 1 WCM12_Z10_12 64069326 74273508 −0.6523 −0.8126 1.0036 0.1351 1 0 WCM12_Z10_1 274273887 119600513 −0.0775 −0.0432 0.9961 0.9448 1 1 WCM12_Z10_1 2119600793 232952369 0.3622 0.4909 1.8622 0.9485 2 1 WCM12_Z10_1 2232975953 242946616 −0.1724 −0.1637 1.8058 −0.0203 2 0 WCM12_Z10_1 2068363 62904835 −0.0457 −0.0034 1.0089 0.9864 1 1 WCM12_Z10_1 21 982620748084214 −0.132 −0.1121 0.9452 0.9053 1 1 WCM12_Z10_1 22 1706353051219138 −0.1094 −0.0835 0.9509 0.9366 1 1 WCM12_Z10_1 3 239472 37778406−0.2507 −0.2646 0.9417 0.7231 1 1 WCM12_Z10_1 3 37783236 197894720−0.0322 0.0135 1.0195 0.9993 1 1 WCM12_Z10_1 4 59361 36069702 −0.8038−1.0359 0.9732 0.0023 1 0 WCM12_Z10_1 4 36069899 169013864 −0.0949−0.0651 0.9619 0.9498 1 1 WCM12_Z10_1 4 169048901 190396288 0.38530.5181 2.0359 0.8282 2 1 WCM12_Z10_1 5 140532 6737737 0.2472 0.35451.6194 0.9377 2 1 WCM12_Z10_1 5 6738823 180486841 −0.0758 −0.0411 0.98050.9633 1 1 WCM12_Z10_1 5 180551500 180687769 0.0861 0.1597 NA NA NA NAWCM12_Z10_1 6 203542 6169570 0.0499 0.1152 1.1471 1.0191 1 1 WCM12_Z10_16 6174866 30139699 0.2531 0.3616 1.5181 1.0515 2 1 WCM12_Z10_1 630140061 101312005 −0.0258 0.0215 1.034 0.996 1 1 WCM12_Z10_1 6101315874 170893409 −0.7557 −0.9637 1.0162 0.0093 1 0 WCM12_Z10_1 7193253 6776956 0.3953 0.5298 1.8841 1.0034 2 1 WCM12_Z10_1 7 677717192462598 −0.0407 0.0029 1.0158 0.9883 1 1 WCM12_Z10_1 7 9273068294827762 −0.7513 −0.9571 NA NA NA NA WCM12_Z10_1 7 94855320 158937074−0.031 0.015 1.0231 0.9979 1 1 WCM12_Z10_1 8 190908 48511513 −0.7616−0.9725 1.0163 0.003 1 0 WCM12_Z10_1 8 48566697 128750683 0.0054 0.06031.0634 1.022 1 1 WCM12_Z10_1 8 128750852 146279513 0.3252 0.4472 1.88610.8406 2 1 WCM12_Z10_1 9 116832 141111414 −0.0046 0.0479 1.044 1.0235 11 WCM12_Z10_1 X 2707682 122840795 −0.0769 −0.0426 NA NA NA NAWCM12_Z10_1 X 122866861 154509348 0.7214 0.9057 NA NA NA NA WCM131 114930 249214018 0.0196 NA NA NA NA NA WCM131 10 225995 135439027 0.0181NA NA NA NA NA WCM131 11 193096 134605916 0.01 NA NA NA NA NA WCM131 12148480 133810868 0.0064 NA NA NA NA NA WCM131 13 19041965 115089411−0.0043 NA NA NA NA NA WCM131 14 19110401 107283269 0.002 NA NA NA NA NAWCM131 15 20083896 102506248 0.025 NA NA NA NA NA WCM131 16 6690490168693 −0.0033 NA NA NA NA NA WCM131 17 131595 81187930 −0.0013 NA NANA NA NA WCM131 18 47799 78005199 0.0076 NA NA NA NA NA WCM131 19 10506959093645 −0.0136 NA NA NA NA NA WCM131 2 41720 243037022 0.0043 NA NA NANA NA WCM131 20 68446 62934592 0.0232 NA NA NA NA NA WCM131 21 959031448084198 0.0136 NA NA NA NA NA WCM131 22 16159021 51223730 0.0331 NA NANA NA NA WCM131 3 239472 197896735 0.009 NA NA NA NA NA WCM131 4 53342190904471 0.0055 NA NA NA NA NA WCM131 5 90576 180687847 0.0069 NA NA NANA NA WCM131 6 203515 170892918 −0.0032 NA NA NA NA NA WCM131 7 193222158937135 0.0065 NA NA NA NA NA WCM131 8 163491 146279527 0.0085 NA NANA NA NA WCM131 9 14893 141107526 0.0131 NA NA NA NA NA WCM131 X 2700145154493598 −0.1115 NA NA NA NA NA WCM131_Z1_1 1 721450 24202102 −0.597 NANA NA NA NA WCM131_Z1_1 1 24255586 26370001 0.1169 NA NA NA NA NAWCM131_Z1_1 1 26370907 116228092 −0.5954 NA NA NA NA NA WCM131_Z1_1 1116233977 145747117 0.0303 NA NA NA NA NA WCM131_Z1_1 1 145748513155238115 0.767 NA NA NA NA NA WCM131_Z1_1 1 155238505 207224048 0.4195NA NA NA NA NA WCM131_Z1_1 1 207224359 249212348 0.0019 NA NA NA NA NAWCM131_Z1_1 10 226016 3822362 0.0027 NA NA NA NA NA WCM131_Z1_1 103823897 14563967 0.4371 NA NA NA NA NA WCM131_Z1_1 10 14572451 1344214270.0218 NA NA NA NA NA WCM131_Z1_1 10 134459468 135170161 0.4274 NA NA NANA NA WCM131_Z1_1 10 135170689 135440068 −0.1036 NA NA NA NA NAWCM131_Z1_1 11 193097 544740 0.0932 NA NA NA NA NA WCM131_Z1_1 11 549959831594 −0.568 NA NA NA NA NA WCM131_Z1_1 11 836266 1075919 −0.0805 NA NANA NA NA WCM131_Z1_1 11 1077710 1580257 0.4471 NA NA NA NA NAWCM131_Z1_1 11 1585102 9466641 0.0546 NA NA NA NA NA WCM131_Z1_1 119492941 10830000 −0.5572 NA NA NA NA NA WCM131_Z1_1 11 10874480 300326220.0254 NA NA NA NA NA WCM131_Z1_1 11 30032899 48238549 −0.5891 NA NA NANA NA WCM131_Z1_1 11 48238633 48997107 −0.5697 NA NA NA NA NAWCM131_Z1_1 11 48997334 50003964 −0.7959 NA NA NA NA NA WCM131_Z1_1 1151411709 62462042 −0.007 NA NA NA NA NA WCM131_Z1_1 11 62470003 62656161−0.5806 NA NA NA NA NA WCM131_Z1_1 11 62677212 82752546 0.0146 NA NA NANA NA WCM131_Z1_1 11 82868529 117060072 −0.5921 NA NA NA NA NAWCM131_Z1_1 11 117060706 117258120 −1.6734 NA NA NA NA NA WCM131_Z1_1 11117261523 134856534 −0.5534 NA NA NA NA NA WCM131_Z1_1 12 148674 12251330.7721 NA NA NA NA NA WCM131_Z1_1 12 1250923 1863601 −0.4715 NA NA NA NANA WCM131_Z1_1 12 1882119 6101103 0.7833 NA NA NA NA NA WCM131_Z1_1 126103308 6761878 1.0964 NA NA NA NA NA WCM131_Z1_1 12 6762126 99072720.7262 NA NA NA NA NA WCM131_Z1_1 12 9907821 27235396 0.4236 NA NA NA NANA WCM131_Z1_1 12 27450665 112681213 0.0098 NA NA NA NA NA WCM131_Z1_112 112681690 115120981 −0.4301 NA NA NA NA NA WCM131_Z1_1 12 115801927123345258 0.0242 NA NA NA NA NA WCM131_Z1_1 12 123345509 123751791−0.5677 NA NA NA NA NA WCM131_Z1_1 12 123780572 133810892 0.0334 NA NANA NA NA WCM131_Z1_1 13 19600475 40174999 0.0329 NA NA NA NA NAWCM131_Z1_1 13 40175313 74536134 −0.5534 NA NA NA NA NA WCM131_Z1_1 1374569131 115089411 0.0157 NA NA NA NA NA WCM131_Z1_1 14 1937771867940191 −0.0232 NA NA NA NA NA WCM131_Z1_1 14 67940419 68331821 0.4085NA NA NA NA NA WCM131_Z1_1 14 68353820 107283055 −0.0757 NA NA NA NA NAWCM131_Z1_1 15 20170149 41625188 0.0147 NA NA NA NA NA WCM131_Z1_1 1541634628 42284971 −0.6115 NA NA NA NA NA WCM131_Z1_1 15 42287659102506284 −0.0021 NA NA NA NA NA WCM131_Z1_1 16 67604 4564091 −0.6007 NANA NA NA NA WCM131_Z1_1 16 4606515 7657307 −0.0329 NA NA NA NA NAWCM131_Z1_1 16 7680646 10788727 0.3699 NA NA NA NA NA WCM131_Z1_1 1610837900 23722339 −0.0645 NA NA NA NA NA WCM131_Z1_1 16 2372337627078284 0.485 NA NA NA NA NA WCM131_Z1_1 16 27078441 70211290 −0.0234NA NA NA NA NA WCM131_Z1_1 16 70255159 70589097 −0.6648 NA NA NA NA NAWCM131_Z1_1 16 70590158 79245678 −0.0449 NA NA NA NA NA WCM131_Z1_1 1679245961 90161578 −0.5959 NA NA NA NA NA WCM131_Z1_1 17 131595 11988810.0273 NA NA NA NA NA WCM131_Z1_1 17 1201548 1782313 −0.5637 NA NA NA NANA WCM131_Z1_1 17 1782634 9843458 0.0148 NA NA NA NA NA WCM131_Z1_1 179846447 11166785 0.3998 NA NA NA NA NA WCM131_Z1_1 17 11282745 580239290.0023 NA NA NA NA NA WCM131_Z1_1 17 58030386 74475409 0.4161 NA NA NANA NA WCM131_Z1_1 17 74475975 81083507 0.0255 NA NA NA NA NA WCM131_Z1_118 49008 78005215 0.0134 NA NA NA NA NA WCM131_Z1_1 19 281439 12461928−0.0051 NA NA NA NA NA WCM131_Z1_1 19 12462873 12924269 −0.7021 NA NA NANA NA WCM131_Z1_1 19 12936591 51631714 −0.0081 NA NA NA NA NAWCM131_Z1_1 19 51633231 59083988 0.7353 NA NA NA NA NA WCM131_Z1_1 241623 43015693 0.003 NA NA NA NA NA WCM131_Z1_1 2 43019627 43547589−1.6013 NA NA NA NA NA WCM131_Z1_1 2 43571344 72960206 −0.018 NA NA NANA NA WCM131_Z1_1 2 72968457 85778171 0.3523 NA NA NA NA NA WCM131_Z1_12 85778728 144966233 0.0042 NA NA NA NA NA WCM131_Z1_1 2 145146448155102330 0.3469 NA NA NA NA NA WCM131_Z1_1 2 155115634 160884867−0.0495 NA NA NA NA NA WCM131_Z1_1 2 160885457 203500084 0.3754 NA NA NANA NA WCM131_Z1_1 2 203500509 204291988 −0.6456 NA NA NA NA NAWCM131_Z1_1 2 204302883 212295757 0.3791 NA NA NA NA NA WCM131_Z1_1 2212426660 213290991 −0.5992 NA NA NA NA NA WCM131_Z1_1 2 213403201233349972 0.0052 NA NA NA NA NA WCM131_Z1_1 2 233351271 241938464−0.6184 NA NA NA NA NA WCM131_Z1_1 2 241969873 242151579 0.1397 NA NA NANA NA WCM131_Z1_1 2 242152031 242946597 −0.5753 NA NA NA NA NAWCM131_Z1_1 20 68363 3520963 −0.5973 NA NA NA NA NA WCM131_Z1_1 203526441 3785506 0.0256 NA NA NA NA NA WCM131_Z1_1 20 3802885 8755241−0.6408 NA NA NA NA NA WCM131_Z1_1 20 8769158 62853302 0.0174 NA NA NANA NA WCM131_Z1_1 20 62854504 62904847 −0.4721 NA NA NA NA NAWCM131_Z1_1 21 9826207 47613559 0.0197 NA NA NA NA NA WCM131_Z1_1 2147614553 47981595 −0.6693 NA NA NA NA NA WCM131_Z1_1 21 4798377948084214 0.1486 NA NA NA NA NA WCM131_Z1_1 22 16287495 50649328−4.00E−04 NA NA NA NA NA WCM131_Z1_1 22 50651066 50885266 −0.5529 NA NANA NA NA WCM131_Z1_1 22 50885604 51215123 0.0295 NA NA NA NA NAWCM131_Z1_1 3 239431 44283843 0.0117 NA NA NA NA NA WCM131_Z1_1 344284584 58923421 −0.5944 NA NA NA NA NA WCM131_Z1_1 3 59032925 710271030.0399 NA NA NA NA NA WCM131_Z1_1 3 71037163 71247364 −1.5966 NA NA NANA NA WCM131_Z1_1 3 71591198 197894719 0.0068 NA NA NA NA NA WCM131_Z1_14 59367 151186883 0.0128 NA NA NA NA NA WCM131_Z1_1 4 151199013151518249 −0.4792 NA NA NA NA NA WCM131_Z1_1 4 151520247 151765916−1.7718 NA NA NA NA NA WCM131_Z1_1 4 151769983 152201053 −0.814 NA NA NANA NA WCM131_Z1_1 4 152203541 155219225 0.004 NA NA NA NA NA WCM131_Z1_14 155219382 190426502 0.4067 NA NA NA NA NA WCM131_Z1_1 5 140636 18808650.6298 NA NA NA NA NA WCM131_Z1_1 5 2747699 51376661 0.0086 NA NA NA NANA WCM131_Z1_1 5 52096412 54721132 −0.6328 NA NA NA NA NA WCM131_Z1_1 554721781 78324352 −0.0131 NA NA NA NA NA WCM131_Z1_1 5 78325809134670827 −0.3184 NA NA NA NA NA WCM131_Z1_1 5 134673651 1806878030.0053 NA NA NA NA NA WCM131_Z1_1 6 203466 43188940 0.0118 NA NA NA NANA WCM131_Z1_1 6 43189484 70778316 0.0131 NA NA NA NA NA WCM131_Z1_1 670812090 137112891 −0.011 NA NA NA NA NA WCM131_Z1_1 6 137113228170893409 0.4307 NA NA NA NA NA WCM131_Z1_1 7 193222 102825981 0.0151 NANA NA NA NA WCM131_Z1_1 7 102850754 104844175 0.4243 NA NA NA NA NAWCM131_Z1_1 7 104844543 133827853 0.0017 NA NA NA NA NA WCM131_Z1_1 7133842826 133991526 0.3116 NA NA NA NA NA WCM131_Z1_1 7 133994206149417995 0.4742 NA NA NA NA NA WCM131_Z1_1 7 149418699 150093875 0.435NA NA NA NA NA WCM131_Z1_1 7 150094218 158937375 −3.00E−04 NA NA NA NANA WCM131_Z1_1 8 190906 41845000 0.0232 NA NA NA NA NA WCM131_Z1_1 841906059 47757650 0.4114 NA NA NA NA NA WCM131_Z1_1 8 47759611 850972400.0129 NA NA NA NA NA WCM131_Z1_1 8 85441778 95895077 0.4035 NA NA NA NANA WCM131_Z1_1 8 95896123 96087877 −0.7941 NA NA NA NA NA WCM131_Z1_1 896166461 122629380 0.4323 NA NA NA NA NA WCM131_Z1_1 8 122641014136561143 0.7553 NA NA NA NA NA WCM131_Z1_1 8 136569699 146157862 0.4791NA NA NA NA NA WCM131_Z1_1 8 146171437 146279480 −0.4805 NA NA NA NA NAWCM131_Z1_1 9 17079 35697908 0.0119 NA NA NA NA NA WCM131_Z1_1 935698051 35846538 −0.5989 NA NA NA NA NA WCM131_Z1_1 9 35846950 791175910.0431 NA NA NA NA NA WCM131_Z1_1 9 79117919 80043826 0.3592 NA NA NA NANA WCM131_Z1_1 9 80046238 119448979 0.0234 NA NA NA NA NA WCM131_Z1_1 9119460046 119976803 −1.1553 NA NA NA NA NA WCM131_Z1_1 9 119977007123875986 0.0084 NA NA NA NA NA WCM131_Z1_1 9 123877378 126429322 0.4983NA NA NA NA NA WCM131_Z1_1 9 126433572 139804431 0.0206 NA NA NA NA NAWCM131_Z1_1 9 139811005 140002847 0.4764 NA NA NA NA NA WCM131_Z1_1 9140003117 141111414 0.0189 NA NA NA NA NA WCM131_Z1_1 X 2707709154509348 −0.0531 NA NA NA NA NA WCM131_Z2_1 1 69569 26857275 −0.2072 NANA NA NA NA WCM131_Z2_1 1 26863426 145598293 −0.0047 NA NA NA NA NAWCM131_Z2_1 1 145598587 145704159 0.2086 NA NA NA NA NA WCM131_Z2_1 1145704302 155282165 0.3809 NA NA NA NA NA WCM131_Z2_1 1 155287964207236767 0.1913 NA NA NA NA NA WCM131_Z2_1 1 207238419 249212341−0.0155 NA NA NA NA NA WCM131_Z2_1 10 226016 3823864 −0.0075 NA NA NA NANA WCM131_Z2_1 10 3824107 14478576 0.234 NA NA NA NA NA WCM131_Z2_1 1014563215 135440086 0.0048 NA NA NA NA NA WCM131_Z2_1 11 193100 1010694−0.0508 NA NA NA NA NA WCM131_Z2_1 11 1011194 1262175 0.1837 NA NA NA NANA WCM131_Z2_1 11 1262541 27395582 0.0072 NA NA NA NA NA WCM131_Z2_1 1127398717 57069403 −0.1861 NA NA NA NA NA WCM131_Z2_1 11 5706969582708344 0.0065 NA NA NA NA NA WCM131_Z2_1 11 82752580 134856542 −0.257NA NA NA NA NA WCM131_Z2_1 12 148673 27235073 0.1898 NA NA NA NA NAWCM131_Z2_1 12 27235334 48963795 −0.0142 NA NA NA NA NA WCM131_Z2_1 1249047845 95044189 0.2097 NA NA NA NA NA WCM131_Z2_1 12 95228244133810892 −0.0037 NA NA NA NA NA WCM131_Z2_1 13 19600515 39616254−0.0185 NA NA NA NA NA WCM131_Z2_1 13 39618262 75936731 −0.2114 NA NA NANA NA WCM131_Z2_1 13 76055514 115089411 −0.0235 NA NA NA NA NAWCM131_Z2_1 14 19377701 107283183 0.006 NA NA NA NA NA WCM131_Z2_1 1520169956 102506284 0.006 NA NA NA NA NA WCM131_Z2_1 16 67604 4621572−0.1874 NA NA NA NA NA WCM131_Z2_1 16 4624731 78466437 −0.0088 NA NA NANA NA WCM131_Z2_1 16 78466635 90161578 −0.2014 NA NA NA NA NAWCM131_Z2_1 17 131595 1961350 −0.154 NA NA NA NA NA WCM131_Z2_1 171961701 74681232 0.0114 NA NA NA NA NA WCM131_Z2_1 17 74684401 81083455−0.2051 NA NA NA NA NA WCM131_Z2_1 18 48992 78005210 −0.0231 NA NA NA NANA WCM131_Z2_1 19 281403 51631695  6.00E−04 NA NA NA NA NA WCM131_Z2_119 51633333 59083929 0.4953 NA NA NA NA NA WCM131_Z2_1 2 41614 311813200.2062 NA NA NA NA NA WCM131_Z2_1 2 31189155 241930672 −0.0124 NA NA NANA NA WCM131_Z2_1 2 241932484 242946604 0.0988 NA NA NA NA NAWCM131_Z2_1 20 68363 9360789 −0.1845 NA NA NA NA NA WCM131_Z2_1 209364917 62904861 0.0167 NA NA NA NA NA WCM131_Z2_1 21 9826235 48084253−0.0198 NA NA NA NA NA WCM131_Z2_1 22 17060362 51215152 0.0081 NA NA NANA NA WCM131_Z2_1 3 239431 43744017 −0.0138 NA NA NA NA NA WCM131_Z2_1 343753334 59032925 −0.2054 NA NA NA NA NA WCM131_Z2_1 3 59035342197894719 −0.0152 NA NA NA NA NA WCM131_Z2_1 4 59382 140325614 −0.0248NA NA NA NA NA WCM131_Z2_1 4 140339071 189061036 0.2284 NA NA NA NA NAWCM131_Z2_1 4 189061749 190426502 −0.0349 NA NA NA NA NA WCM131_Z2_1 5140636 1880865 0.2959 NA NA NA NA NA WCM131_Z2_1 5 2747681 157078475−0.0196 NA NA NA NA NA WCM131_Z2_1 5 157078670 180687814 0.1428 NA NA NANA NA WCM131_Z2_1 6 203561 137113046 −0.0208 NA NA NA NA NA WCM131_Z2_16 137113256 170893407 0.1542 NA NA NA NA NA WCM131_Z2_1 7 193205158937416 −0.0151 NA NA NA NA NA WCM131_Z2_1 8 190897 100836135 −0.0117NA NA NA NA NA WCM131_Z2_1 8 100844699 100974956 0.313 NA NA NA NA NAWCM131_Z2_1 8 100975194 123965175 0.1837 NA NA NA NA NA WCM131_Z2_1 8123965501 146157545 0.3664 NA NA NA NA NA WCM131_Z2_1 8 146157781146279508 −0.3054 NA NA NA NA NA WCM131_Z2_1 9 17079 141111414 −0.0021NA NA NA NA NA WCM131_Z2_1 X 2707734 154509348 −0.0966 NA NA NA NA NAWCM1388 1 69592 58522014 0.1518 −0.0609 0.9587 0.9587 1 1 WCM1388 158939502 119427436 −0.6369 −0.9213 1.0489 0.0072 1 0 WCM1388 1 119427676154474377 0.323 0.121 1.099 1.076 1 1 WCM1388 1 154479415 1556492910.8946 0.72 2.3572 0.9371 2 1 WCM1388 1 155658085 249212354 0.144−0.0692 0.9531 0.9531 1 1 WCM1388 10 225982 81113556 0.1558 −0.05670.9615 0.9615 1 1 WCM1388 10 81146112 96109022 −0.7514 −1.0502 0.9739−0.0081 1 0 WCM1388 10 96110038 117825099 −0.1656 −0.4021 1.0152 0.49831 0 WCM1388 10 117849361 118117368 −0.8099 −1.1167 NA NA NA NA WCM138810 118137967 135378918 0.2354 0.0281 1.024 1.0153 1 1 WCM1388 11 193096134257753 0.0572 −0.1621 0.8937 0.8937 1 1 WCM1388 12 148642 1338109050.17 −0.0415 0.9716 0.9716 1 1 WCM1388 13 19600326 33241911 0.2022−0.0072 1.0003 0.9897 1 1 WCM1388 13 33247408 76445044 −0.6502 −0.93621.0487 −0.0034 1 0 WCM1388 13 76447830 113153315 0.123 −0.0916 0.94350.9334 1 1 WCM1388 13 113153523 115089411 −0.5887 −0.8674 1.0928 0.00351 0 WCM1388 14 19110187 107283026 0.4248 0.2285 1.399 0.9443 1 1 WCM138815 20083905 102506240 −0.6994 −0.9915 1.013 −0.0072 1 0 WCM1388 16 6716673177632 0.1405 −0.0729 0.9507 0.9507 1 1 WCM1388 16 74330836 90110890−0.6543 −0.9408 1.0414 5.00E−04 1 0 WCM1388 16 90124832 90161568 0.34630.1456 NA NA NA NA WCM1388 17 131595 7960947 −0.7137 −1.0077 1.0018−0.0072 1 0 WCM1388 17 7976212 81052262 0.1774 −0.0337 0.9769 0.9769 1 1WCM1388 18 47653 13826391 0.2 −0.0096 0.9934 0.9934 1 1 WCM1388 1813826508 23866281 0.6275 0.4415 1.6893 1.0267 2 1 WCM1388 18 2386648229672894 0.1486 −0.0643 0.9891 0.9238 1 1 WCM1388 18 29691756 78005210−0.7573 −1.057 0.969 −0.0077 1 0 WCM1388 19 281506 1555325 −0.0196−0.2445 0.8605 0.8278 1 1 WCM1388 19 1555725 2643436 −0.6196 −0.90191.0737 −0.0033 1 0 WCM1388 19 2717256 11436268 0.287 0.0829 1.05911.0591 1 1 WCM1388 19 11446278 14561908 −0.4419 −0.7044 1.2289 −0.0015 10 WCM1388 19 14562848 43016548 0.2604 0.0547 1.0386 1.0386 1 1 WCM138819 43023080 43858093 2.242 2.101 4.3554 4.2248 4 4 WCM1388 19 4385844252873183 0.1983 −0.0114 0.9922 0.9922 1 1 WCM1388 19 52876385 542657221.3852 1.2266 2.3402 2.3402 2 2 WCM1388 19 54290902 59083985 0.3315 0.131.107 1.0815 1 1 WCM1388 2 41509 33952621 −0.1689 −0.4057 0.9784 0.53141 1 WCM1388 2 33952867 43514248 −0.6197 −0.902 1.0658 0.0045 1 0 WCM13882 43518858 242946616 −0.1513 −0.3867 0.9994 0.5304 1 1 WCM1388 20 6837562905001 0.1172 −0.0979 0.9344 0.9344 1 1 WCM1388 21 9907270 480841630.1903 −0.0199 0.9916 0.9811 1 1 WCM1388 22 17072119 51219129 −0.7158−1.01 0.9953 −0.0022 1 0 WCM1388 3 239405 16645969 0.1903 −0.0199 0.98630.9863 1 1 WCM1388 3 16679531 29910445 −0.7221 −1.0171 1.0107 −0.0225 10 WCM1388 3 29922333 35758749 0.2747 0.0698 1.1376 0.9616 1 1 WCM1388 335763202 89521725 −0.7853 −1.0886 0.9508 −0.0104 1 0 WCM1388 3 89528644197894744 0.6809 0.4974 1.8543 0.969 2 1 WCM1388 4 53349 77039174−0.1072 −0.3389 1.0196 0.5616 1 1 WCM1388 4 77039412 152096297 −0.6747−0.9637 0.5168 0.5087 1 1 WCM1388 4 152096526 190396290 −0.1837 −0.42180.9596 0.5334 1 1 WCM1388 5 140598 70942059 0.1877 −0.0227 0.9844 0.98441 1 WCM1388 5 70944988 74877140 −0.6709 −0.9594 1.0311 −0.0026 1 0WCM1388 5 74879106 180687800 0.1401 −0.0734 0.9504 0.9504 1 1 WCM1388 6203588 89673141 0.1708 −0.0406 0.9722 0.9722 1 1 WCM1388 6 89675638131894392 −0.7239 −1.0191 0.9988 −0.012 1 0 WCM1388 6 131895418132859437 −0.0348 −0.2608 NA NA NA NA WCM1388 6 132859749 1430947240.146 −0.0671 0.978 0.9311 1 1 WCM1388 6 143095045 170893411 −0.2292−0.4713 0.9537 0.4889 1 0 WCM1388 7 193205 5360661 0.2682 0.0629 1.06671.0224 1 1 WCM1388 7 5363981 56879527 −0.7139 −1.0079 0.9961 −0.0015 1 0WCM1388 7 57194311 158937375 −0.1787 −0.4164 0.9648 0.5338 1 1 WCM1388 8190907 48686936 −0.6999 −0.992 1.0116 −0.006 1 0 WCM1388 8 4868944887242489 0.7946 0.616 2.0978 0.9675 2 1 WCM1388 8 87386324 1105900461.254 1.0917 3.275 0.9876 3 1 WCM1388 8 110592226 114290824 −0.5751−0.8522 NA NA NA NA WCM1388 8 114326961 131848465 1.2555 1.0933 3.22571.0415 3 1 WCM1388 8 131848728 143395808 0.7506 0.5701 1.9538 1.0154 2 1WCM1388 8 143396408 146279441 −0.8508 −1.1633 0.9089 −0.0159 1 0 WCM13889 116887 141071710 0.1721 −0.0393 0.9731 0.9731 1 1 WCM1388 X 2707715154509348 0.1217 −0.0931 NA NA NA NA WCM1388_Z3_1 1 69590 57756687 0.1680.0258 1.018 1.018 1 1 WCM1388_Z3_1 1 58521986 119427454 −0.7627 −1.0051.0024 −0.0059 1 0 WCM1388_Z3_1 1 119427796 154442830 0.1511 0.00771.0518 0.9589 1 1 WCM1388_Z3_1 1 154456643 155631029 1.0715 0.97812.9209 1.0189 3 1 WCM1388_Z3_1 1 155638491 249212432 0.1256 −0.01980.9938 0.9789 1 1 WCM1388_Z3_1 10 225960 81111240 0.1296 −0.0154 0.98940.9894 1 1 WCM1388_Z3_1 10 81112114 96356617 −0.7764 −1.0208 1.0013−0.0156 1 0 WCM1388_Z3_1 10 96443723 120446120 −0.2406 −0.4181 0.99720.4997 1 0 WCM1388_Z3_1 10 120450859 135440080 0.1362 −0.0084 1.0070.9813 1 1 WCM1388_Z3_1 11 193097 134856512 0.1369 −0.0076 1.0011 0.98831 1 WCM1388_Z3_1 12 148639 133810892 0.1418 −0.0023 1.0048 0.9919 1 1WCM1388_Z3_1 13 19600364 33241969 0.13 −0.0151 1.0237 0.9555 1 1WCM1388_Z3_1 13 33247409 76457200 −0.764 −1.0065 1.0307 −0.0352 1 0WCM1388_Z3_1 13 77459417 80122525 0.1103 −0.0362 NA NA NA NAWCM1388_Z3_1 13 80125207 92345556 −0.8499 −1.1058 NA NA NA NAWCM1388_Z3_1 13 92345724 113088860 0.1267 −0.0186 1.001 0.9734 1 1WCM1388_Z3_1 13 113144002 115089411 −0.7386 −0.9773 0.9984 0.0175 1 0WCM1388_Z3_1 14 19377716 60591863 0.4234 0.2984 1.4817 0.9779 1 1WCM1388_Z3_1 14 60592390 62462947 −0.2088 −0.3832 NA NA NA NAWCM1388_Z3_1 14 62463214 107283220 0.4359 0.3116 1.4899 0.9923 1 1WCM1388_Z3_1 15 20170159 22319166 −1.5028 −1.8991 NA NA NA NAWCM1388_Z3_1 15 22319565 23685583 −0.7359 −0.9742 0.8024 0.2157 1 0WCM1388_Z3_1 15 23686112 102506282 −0.7473 −0.9872 1.0135 −0.0045 1 0WCM1388_Z3_1 16 67604 73521333 0.1595 0.0167 1.0225 1.0007 1 1WCM1388_Z3_1 16 74321131 90233603 −0.7193 −0.9551 1.0277 0.0039 1 0WCM1388_Z3_1 17 131595 7960881 −0.741 −0.98 1.0188 −0.0048 1 0WCM1388_Z3_1 17 7976137 81083567 0.1612 0.0185 1.0129 1.0129 1 1WCM1388_Z3_1 18 48339 21033462 0.1395 −0.0048 1.0042 0.9892 1 1WCM1388_Z3_1 18 21042940 23901053 0.6808 0.5702 2.0291 0.9403 2 1WCM1388_Z3_1 18 23907073 29691764 0.0702 −0.0795 NA NA NA NAWCM1388_Z3_1 18 29770050 78005206 −0.7625 −1.0048 1.0077 −0.011 1 0WCM1388_Z3_1 19 281534 1556921 0.1709 0.0289 1.064 0.9764 1 1WCM1388_Z3_1 19 1567500 2643479 −0.6975 −0.9302 1.057 −0.0075 1 0WCM1388_Z3_1 19 2717256 11422816 0.1587 0.0159 1.011 1.011 1 1WCM1388_Z3_1 19 11436119 14574916 −0.7198 −0.9557 1.0326 −0.0014 1 0WCM1388_Z3_1 19 14578566 59083970 0.1306 −0.0144 0.9954 0.9848 1 1WCM1388_Z3_1 2 41609 33952621 −0.2299 −0.4064 0.9918 0.5172 1 1WCM1388_Z3_1 2 36605503 43452793 −0.714 −0.949 1.0021 0.0339 1 0WCM1388_Z3_1 2 43453408 242946589 −0.2508 −0.4294 0.9904 0.4948 1 0WCM1388_Z3_1 20 68351 62904890 0.1478 0.0041 1.0071 0.9985 1 1WCM1388_Z3_1 21 9907283 48084282 0.119 −0.0269 0.9899 0.973 1 1WCM1388_Z3_1 22 17063523 51215157 −0.7289 −0.9661 1.0221 0.0016 1 0WCM1388_Z3_1 3 239431 16640013 0.156 0.0129 1.0296 0.9884 1 1WCM1388_Z3_1 3 16645993 27763624 −0.7709 −1.0144 NA NA NA NAWCM1388_Z3_1 3 28283353 29804441 0.1008 −0.0465 NA NA NA NA WCM1388_Z3_13 29910449 32767034 0.7263 0.618 NA NA NA NA WCM1388_Z3_1 3 3276919136485003 0.0819 −0.0669 NA NA NA NA WCM1388_Z3_1 3 36524545 79638984−0.7359 −0.9742 1.0226 −0.0046 1 0 WCM1388_Z3_1 3 81539593 895216930.1601 0.0173 NA NA NA NA WCM1388_Z3_1 3 89528635 197894726 0.67390.5629 1.9679 0.9867 2 1 WCM1388_Z3_1 4 59339 74606389 −0.2261 −0.40220.9905 0.5229 1 1 WCM1388_Z3_1 4 74607384 152096321 −0.7608 −1.00280.557 0.441 1 0 WCM1388_Z3_1 4 152198354 190426471 −0.2556 −0.43470.9827 0.4969 1 0 WCM1388_Z3_1 5 140608 70900240 0.1163 −0.0299 0.99320.9658 1 1 WCM1388_Z3_1 5 70922536 74801833 −0.7221 −0.9583 1.035−0.0057 1 0 WCM1388_Z3_1 5 74806969 180687814 0.0936 −0.0543 0.97240.9537 1 1 WCM1388_Z3_1 6 203516 89601562 0.129 −0.0162 0.9952 0.9825 11 WCM1388_Z3_1 6 89614462 131603572 −0.7736 −1.0175 0.9978 −0.0098 1 0WCM1388_Z3_1 6 131894425 143095570 0.1412 −0.003 1.0419 0.9539 1 1WCM1388_Z3_1 6 143095824 170893454 −0.2547 −0.4336 0.9647 0.5161 1 1WCM1388_Z3_1 7 193222 803563 0.0463 −0.1053 NA NA NA NA WCM1388_Z3_1 7808827 1579908 0.4451 0.3214 1.3423 1.1568 1 1 WCM1388_Z3_1 7 15866625028762 0.1728 0.0309 1.048 0.9953 1 1 WCM1388_Z3_1 7 5036270 62758670−0.7563 −0.9976 1.0009 8.00E−04 1 0 WCM1388_Z3_1 7 63529270 158937375−0.3178 −0.5034 0.9428 0.4681 1 0 WCM1388_Z3_1 8 190900 47753945 −0.7506−0.991 1.0109 −0.0047 1 0 WCM1388_Z3_1 8 47755043 65291808 0.5544 0.43711.8883 0.8194 2 1 WCM1388_Z3_1 8 65489055 82571682 1.0211 0.9258 2.77061.0287 3 1 WCM1388_Z3_1 8 82572782 92364100 0.7491 0.6419 2.1819 0.93882 1 WCM1388_Z3_1 8 92365182 105839705 1.3632 1.2799 3.9528 0.9036 4 1WCM1388_Z3_1 8 105907645 110703578 1.0727 0.9793 2.9888 0.9543 3 1WCM1388_Z3_1 8 110980424 114111040 −0.7258 −0.9626 NA NA NA NAWCM1388_Z3_1 8 114186003 120431585 0.9628 0.8651 NA NA NA NAWCM1388_Z3_1 8 120435302 131796024 1.3253 1.2408 3.741 0.9855 4 1WCM1388_Z3_1 8 131797655 132002781 0.8639 0.7619 NA NA NA NAWCM1388_Z3_1 8 132051784 141856708 0.6638 0.5523 1.9104 1.0224 2 1WCM1388_Z3_1 8 141889725 143381993 1.0771 0.9839 NA NA NA NAWCM1388_Z3_1 8 143395750 146279441 −0.7273 −0.9643 1.0257 −6.00E−04  1 0WCM1388_Z3_1 9 17049 2047423 0.1319 −0.013 NA NA NA NA WCM1388_Z3_1 92054640 3248083 −0.7663 −1.0091 NA NA NA NA WCM1388_Z3_1 9 3257165141111414 0.1358 −0.0088 0.9982 0.9896 1 1 WCM1388_Z3_1 X 2707708154509348 0.0714 −0.0782 NA NA NA NA WCM139 1 17479 249213973 0.02710.1771 1.1306 1.1306 1 1 WCM139 10 225980 135477892 0.0153 0.0179 1.01251.0125 1 1 WCM139 11 193152 62327315 0.0269 0.1748 1.1288 1.1288 1 1WCM139 11 62327496 66453823 −0.0869 −4.8337 0.115 −0.0449 0 0 WCM139 1166453849 134605906 0.0137 −0.0046 0.9968 0.9968 1 1 WCM139 12 148560133810905 −0.0065 −0.3247 0.7985 0.7985 1 1 WCM139 13 19042004 1150894110.0014 −0.1917 0.8756 0.8756 1 1 WCM139 14 19110343 107283263 0.0049−0.1358 0.9102 0.9102 1 1 WCM139 15 20083857 102514263 0.0231 0.1251.0905 1.0905 1 1 WCM139 16 64396 90260461 0.0035 −0.1575 0.8966 0.89661 1 WCM139 17 131595 81052551 0.0108 −0.0471 0.9679 0.9679 1 1 WCM139 1847611 78005194 0.0174 0.0479 1.0338 1.0338 1 1 WCM139 19 105080 59093645−0.0243 −0.6768 0.6255 0.6255 1 1 WCM139 2 41647 243037045 0.0022 −0.1790.8833 0.8833 1 1 WCM139 20 68373 62934617 0.0427 0.3645 1.2874 1.2874 11 WCM139 21 9590305 48084167 0.0106 −0.049 0.9666 0.9666 1 1 WCM139 2216159016 51223730 0.05 0.445 1.3613 1.3613 1 1 WCM139 3 239377 1978966780.0155 0.0212 1.0148 1.0148 1 1 WCM139 4 53333 190878508 0.0113 −0.03840.9737 0.9737 1 1 WCM139 5 90680 180687800 −0.0056 −0.3089 0.8072 0.80721 1 WCM139 6 203466 170892848 −0.0033 −0.2687 0.8301 0.8301 1 1 WCM139 7193222 158937074 0.006 −0.118 0.9215 0.9215 1 1 WCM139 8 163527146279431 0.0237 0.1325 1.0962 1.0962 1 1 WCM139 9 14856 1411075390.0285 0.1945 1.1443 1.1443 1 1 WCM139 X 2700082 154493585 −0.0842−4.0575 NA NA NA NA WCM139_Z3_1 1 721450 29696240 −0.2217 0.0065 1.01940.9896 1 1 WCM139_Z3_1 1 31186427 33502336 0.253 0.5727 NA NA NA NAWCM139_Z3_1 1 33547875 43042703 −0.2242 0.0035 1.0148 0.99 1 1WCM139_Z3_1 1 43047057 46212067 0.7792 1.1668 2.337 2.1535 2 2WCM139_Z3_1 1 46290201 51121156 −0.1234 0.1269 1.2073 0.9765 1 1WCM139_Z3_1 1 51171529 54871659 0.697 1.0757 3.3211 0.8944 3 1WCM139_Z3_1 1 55014015 76349378 −0.1932 0.0416 1.0469 1.0116 1 1WCM139_Z3_1 1 76356455 84348786 0.4004 0.7421 NA NA NA NA WCM139_Z3_1 184352964 148022941 −0.2378 −0.0133 1.0202 0.9614 1 1 WCM139_Z3_1 1149871721 150082689 0.1435 0.4451 NA NA NA NA WCM139_Z3_1 1 150117036150830834 0.9386 1.3419 NA NA NA NA WCM139_Z3_1 1 150899274 1518235900.2637 0.5851 NA NA NA NA WCM139_Z3_1 1 151824852 153911501 −0.2838−0.0705 0.9986 0.906 1 1 WCM139_Z3_1 1 153912245 156316586 0.6082 0.9767NA NA NA NA WCM139_Z3_1 1 156337578 156639578 0.2643 0.5858 NA NA NA NAWCM139_Z3_1 1 156639753 156670774 0.3366 0.6691 NA NA NA NA WCM139_Z3_11 156675190 171958254 −0.2252 0.0022 1.0337 0.9694 1 1 WCM139_Z3_1 1172007529 203465342 0.2475 0.5663 1.9679 0.9936 2 1 WCM139_Z3_1 1203466231 206325358 0.649 1.0223 2.0606 2.0017 2 2 WCM139_Z3_1 1206328803 213445925 0.2806 0.6047 2.0086 1.0327 2 1 WCM139_Z3_1 1214170023 215820956 0.9015 1.3013 NA NA NA NA WCM139_Z3_1 1 215821999233807102 0.2426 0.5607 1.9195 1.0305 2 1 WCM139_Z3_1 1 233807277236744544 0.9716 1.3779 NA NA NA NA WCM139_Z3_1 1 236746079 2492125570.2398 0.5574 1.946 0.9973 2 1 WCM139_Z3_1 10 225988 3824017 −0.2368−0.0121 1.0284 0.9549 1 1 WCM139_Z3_1 10 3824319 6557064 0.6177 0.9874NA NA NA NA WCM139_Z3_1 10 7205750 13900896 −0.2459 −0.0234 1.00710.9608 1 1 WCM139_Z3_1 10 14013711 17738786 0.4191 0.7633 2.0143 1.38062 1 WCM139_Z3_1 10 17742207 71175693 −0.208 0.0234 1.0351 0.9976 1 1WCM139_Z3_1 10 71176012 74322689 0.2551 0.5752 1.9469 1.0329 2 1WCM139_Z3_1 10 74326500 79396145 −0.2363 −0.0115 NA NA NA NA WCM139_Z3_110 79397272 81051929 0.1903 0.4999 NA NA NA NA WCM139_Z3_1 10 81052593119044964 −0.2216 0.0067 1.0183 0.991 1 1 WCM139_Z3_1 10 119049804123687875 0.2439 0.5622 NA NA NA NA WCM139_Z3_1 10 123718917 126370945−0.1895 0.0462 1.0756 0.9895 1 1 WCM139_Z3_1 10 126384749 1342615200.0487 0.3334 1.6141 0.9057 2 1 WCM139_Z3_1 10 134351675 135440090−0.2456 −0.0229 1.0391 0.9294 1 1 WCM139_Z3_1 11 193100 19258908 −0.22230.0059 1.0239 0.9842 1 1 WCM139_Z3_1 11 19259453 33308189 0.1289 0.42811.7641 0.9267 2 1 WCM139_Z3_1 11 33308347 34938265 −0.2122 0.0183 1.06020.9654 1 1 WCM139_Z3_1 11 34963416 36680592 0.4028 0.7448 NA NA NA NAWCM139_Z3_1 11 40136001 64627769 −0.215 0.0148 1.0352 0.9854 1 1WCM139_Z3_1 11 64641974 65063051 0.5859 0.9517 NA NA NA NA WCM139_Z3_111 65063487 65147603 0.8579 1.2535 NA NA NA NA WCM139_Z3_1 11 6514804765628185 1.1235 1.5428 3.8643 1.9628 4 2 WCM139_Z3_1 11 6562855366360473 0.6212 0.9913 1.9879 1.9879 2 2 WCM139_Z3_1 11 6636076066619263 0.2419 0.5598 NA NA NA NA WCM139_Z3_1 11 66620052 672900840.5749 0.9394 2.8067 1.0288 3 1 WCM139_Z3_1 11 67351627 70333182 0.24070.5585 2.0242 0.9213 2 1 WCM139_Z3_1 11 70333611 85671739 −0.1924 0.04261.1716 0.8883 1 1 WCM139_Z3_1 11 85687682 87847223 0.5986 0.9661 NA NANA NA WCM139_Z3_1 11 87882970 100999754 −0.2305 −0.0043 1.0783 0.9158 11 WCM139_Z3_1 11 101323826 103339409 0.3667 0.7036 1.8316 1.4255 2 1WCM139_Z3_1 11 103349844 117857338 −0.2445 −0.0216 1.0083 0.962 1 1WCM139_Z3_1 11 117857450 118851234 0.2633 0.5846 2.006 0.9932 2 1WCM139_Z3_1 11 118867772 128856536 −0.2419 −0.0184 1.0118 0.9629 1 1WCM139_Z3_1 11 128857968 134856597 0.1715 0.478 1.8419 0.9436 2 1WCM139_Z3_1 12 148674 6730347 −0.2266  4.00E−04 1.0374 0.9633 1 1WCM139_Z3_1 12 6747529 10366463 0.2667 0.5886 2.0479 0.9597 2 1WCM139_Z3_1 12 10373232 40619418 −0.2258 0.0015 1.0282 0.9739 1 1WCM139_Z3_1 12 40626183 43750297 0.2471 0.5658 1.969 0.9915 2 1WCM139_Z3_1 12 43763113 52345582 −0.2269  1.00E−04 1.0124 0.9877 1 1WCM139_Z3_1 12 52369080 54625185 0.2807 0.6048 2.0333 1.0082 2 1WCM139_Z3_1 12 54635536 57146079 −0.2391 −0.0149 1.0607 0.9187 1 1WCM139_Z3_1 12 57167675 59284534 0.2581 0.5786 1.9772 1.0096 2 1WCM139_Z3_1 12 59307786 68052493 −0.1336 0.1145 1.1432 1.022 1 1WCM139_Z3_1 12 68549153 71533533 0.2691 0.5914 2.0761 0.9373 2 1WCM139_Z3_1 12 71537944 79611374 −0.2346 −0.0094 1.0807 0.9063 1 1WCM139_Z3_1 12 79679648 83324244 0.5022 0.8576 NA NA NA NA WCM139_Z3_112 83358857 88374127 −0.2777 −0.0629 NA NA NA NA WCM139_Z3_1 12 8837690891572214 0.2917 0.6175 NA NA NA NA WCM139_Z3_1 12 92380427 122243074−0.2186 0.0104 1.032 0.9824 1 1 WCM139_Z3_1 12 122243884 1227244810.2269 0.5424 NA NA NA NA WCM139_Z3_1 12 122726964 133810752 −0.238−0.0135 1.0029 0.9784 1 1 WCM139_Z3_1 13 19600515 36521571 −0.19990.0333 1.0372 1.0095 1 1 WCM139_Z3_1 13 36686097 40362474 0.3314 0.6631NA NA NA NA WCM139_Z3_1 13 41133822 44463003 −0.2269  1.00E−04 NA NA NANA WCM139_Z3_1 13 44464314 48523122 0.2446 0.563 1.8693 1.0853 2 1WCM139_Z3_1 13 48523626 70281778 −0.2532 −0.0325 1.0129 0.9426 1 1WCM139_Z3_1 13 70293693 115089411 −0.9337 −0.9382 1.0075 0.0362 1 0WCM139_Z3_1 14 19377692 45639921 −0.2115 0.0191 1.0445 0.9821 1 1WCM139_Z3_1 14 45642275 52188693 0.2459 0.5645 1.9467 1.0111 2 1WCM139_Z3_1 14 52192560 57684711 0.8459 1.2404 2.9158 1.8094 3 2WCM139_Z3_1 14 57686153 59113803 0.2798 0.6037 NA NA NA NA WCM139_Z3_114 59730325 60113684 0.8961 1.2955 NA NA NA NA WCM139_Z3_1 14 6019364673440893 0.2601 0.5809 1.9509 1.0407 2 1 WCM139_Z3_1 14 7344148474370681 0.6875 1.0652 NA NA NA NA WCM139_Z3_1 14 74371774 1072830270.3006 0.6277 2.0363 1.0539 2 1 WCM139_Z3_1 15 20170065 25485047 −0.2754−0.06 0.9855 0.933 1 1 WCM139_Z3_1 15 25486929 33905410 0.1326 0.43231.7359 0.9629 2 1 WCM139_Z3_1 15 33916210 45983178 −0.2235 0.0043 1.02030.9857 1 1 WCM139_Z3_1 15 47873549 49867217 0.2563 0.5765 NA NA NA NAWCM139_Z3_1 15 49869018 64962630 −0.2183 0.0108 1.0547 0.9603 1 1WCM139_Z3_1 15 64966287 66161902 0.2683 0.5904 2.0695 0.9418 2 1WCM139_Z3_1 15 66169731 78211164 −0.2197 0.009 1.0459 0.9665 1 1WCM139_Z3_1 15 78211598 78640285 0.3125 0.6414 NA NA NA NA WCM139_Z3_115 78730689 80988319 −0.2589 −0.0395 NA NA NA NA WCM139_Z3_1 15 8104194183673685 0.22 0.5344 1.864 1.0327 2 1 WCM139_Z3_1 15 83674420 87572062−0.2432 −0.0201 1.057 0.9154 1 1 WCM139_Z3_1 15 88420207 91145581 0.28740.6124 1.8939 1.1638 2 1 WCM139_Z3_1 15 91147681 102514188 −0.22440.0032 1.0529 0.9515 1 1 WCM139_Z3_1 16 66926 396911 0.2808 0.6049 NA NANA NA WCM139_Z3_1 16 417421 1808983 −0.2057 0.0263 1.1362 0.9006 1 1WCM139_Z3_1 16 1809990 2376459 0.2535 0.5734 1.9169 1.0591 2 1WCM139_Z3_1 16 2378556 2854443 0.7069 1.0868 NA NA NA NA WCM139_Z3_1 162854940 3658959 0.3124 0.6413 2.1644 0.955 2 1 WCM139_Z3_1 16 370545414403204 −0.2125 0.0178 1.0835 0.9414 1 1 WCM139_Z3_1 16 1453060315493299 0.3674 0.7044 NA NA NA NA WCM139_Z3_1 16 15494662 23417575−0.2236 0.0042 1.0178 0.9881 1 1 WCM139_Z3_1 16 23424885 31161332 0.23320.5498 2.004 0.9238 2 1 WCM139_Z3_1 16 31191534 33962083 −0.2244 0.00331.0567 0.9478 1 1 WCM139_Z3_1 16 34256804 49672775 0.4091 0.752 2.26941.0989 2 1 WCM139_Z3_1 16 49764710 68338019 −0.2292 −0.0027 1.02280.9735 1 1 WCM139_Z3_1 16 68344256 71660460 −0.988 −1.0176 0.9923−0.0044 1 0 WCM139_Z3_1 16 71663281 72124583 −0.2399 −0.016 NA NA NA NAWCM139_Z3_1 16 72130203 79998102 −0.9915 −1.0227 0.99 −0.0056 1 0WCM139_Z3_1 16 80574703 81301694 −0.2079 0.0235 2.0723 −0.0394 2 0WCM139_Z3_1 16 81303866 90233622 −0.9512 −0.9636 0.9918 0.0337 1 0WCM139_Z3_1 17 131595 1198796 −0.2013 0.0316 NA NA NA NA WCM139_Z3_1 171201557 2324082 0.5995 0.967 2.9115 0.998 3 1 WCM139_Z3_1 17 23414213592019 0.2022 0.5138 1.8766 0.9789 2 1 WCM139_Z3_1 17 3592816 41455630.6304 1.0015 3.04 0.9643 3 1 WCM139_Z3_1 17 4166914 7456905 −0.2638−0.0456 0.9942 0.9436 1 1 WCM139_Z3_1 17 7460163 8012560 0.1964 0.5071.8814 0.9608 2 1 WCM139_Z3_1 17 8013280 12656601 −0.2555 −0.0352 1.02910.9226 1 1 WCM139_Z3_1 17 12659793 15154966 0.2204 0.5349 NA NA NA NAWCM139_Z3_1 17 15162496 19555902 −0.242 −0.0186 1.0178 0.9567 1 1WCM139_Z3_1 17 19559771 20013850 0.2272 0.5428 NA NA NA NA WCM139_Z3_117 20107768 27382139 −0.2222 0.006 1.0933 0.915 1 1 WCM139_Z3_1 1727382899 29902503 0.232 0.5484 1.8578 1.067 2 1 WCM139_Z3_1 17 2990264935295109 −0.2323 −0.0065 1.0385 0.9524 1 1 WCM139_Z3_1 17 3529551135969400 0.1694 0.4755 NA NA NA NA WCM139_Z3_1 17 35974350 37564678−0.2645 −0.0465 1.0164 0.9202 1 1 WCM139_Z3_1 17 37564803 401073220.2478 0.5667 2.1297 0.8326 2 1 WCM139_Z3_1 17 40113427 44632696 −0.2485−0.0266 1.0182 0.9453 1 1 WCM139_Z3_1 17 44770354 45662923 0.2033 0.5151NA NA NA NA WCM139_Z3_1 17 45663749 46940405 −0.219 0.0099 NA NA NA NAWCM139_Z3_1 17 46941682 47700140 0.1891 0.4985 NA NA NA NA WCM139_Z3_117 47778827 57352498 −0.1996 0.0337 1.0576 0.9897 1 1 WCM139_Z3_1 1757430917 61021614 0.5114 0.868 2.0393 1.6109 2 2 WCM139_Z3_1 17 6115137172200289 −0.2449 −0.0221 1.0031 0.9665 1 1 WCM139_Z3_1 17 7220035576060954 0.2408 0.5586 1.9048 1.0408 2 1 WCM139_Z3_1 17 7606387179108177 0.6091 0.9777 3.0383 0.9005 3 1 WCM139_Z3_1 17 7913947379686863 1.2967 1.7291 NA NA NA NA WCM139_Z3_1 17 79766901 810834550.6138 0.983 2.9539 0.9993 3 1 WCM139_Z3_1 18 48213 9275534 −0.2326−0.007 1.0333 0.9571 1 1 WCM139_Z3_1 18 9279602 12948193 0.8095 1.20033.5894 1.0063 4 1 WCM139_Z3_1 18 12963341 25727674 −0.2176 0.0116 NA NANA NA WCM139_Z3_1 18 27878913 30093503 0.5305 0.8895 NA NA NA NAWCM139_Z3_1 18 30093721 43796059 −0.22 0.0086 1.0271 0.9849 1 1WCM139_Z3_1 18 43796338 46343675 0.2566 0.5769 NA NA NA NA WCM139_Z3_118 46383964 55398796 −0.1932 0.0416 1.071 0.9875 1 1 WCM139_Z3_1 1855398922 59739939 0.287 0.612 2.2952 0.7615 2 1 WCM139_Z3_1 18 5974202360572499 −0.2496 −0.028 NA NA NA NA WCM139_Z3_1 18 60582155 642359220.2482 0.5672 NA NA NA NA WCM139_Z3_1 18 64239251 78005224 −0.2377−0.0133 1.0791 0.9026 1 1 WCM139_Z3_1 19 281467 1650211 −0.3001 −0.09080.939 0.939 1 1 WCM139_Z3_1 19 1753670 2807738 0.2187 0.5329 1.92610.9677 2 1 WCM139_Z3_1 19 2808388 14302221 −0.2503 −0.0288 0.9985 0.9621 1 WCM139_Z3_1 19 14492335 16799176 0.2484 0.5674 1.9624 1.0012 2 1WCM139_Z3_1 19 16842052 21607380 −0.2301 −0.0038 1.0306 0.9641 1 1WCM139_Z3_1 19 21607737 30934589 0.4229 0.7677 1.8169 1.5883 2 2WCM139_Z3_1 19 30934880 42753380 −0.2546 −0.0342 0.9996 0.9536 1 1WCM139_Z3_1 19 42753466 46214570 0.2192 0.5335 1.905 0.9899 2 1WCM139_Z3_1 19 46214902 51961604 −0.258 −0.0384 0.9931 0.9544 1 1WCM139_Z3_1 19 51979838 52579362 0.2668 0.5887 1.9141 1.0936 2 1WCM139_Z3_1 19 52580310 53518635 −0.1874 0.0487 1.0788 0.9899 1 1WCM139_Z3_1 19 53553335 54973533 0.2251 0.5404 1.9796 0.9291 2 1WCM139_Z3_1 19 55087523 56226552 0.599 0.9665 2.8601 1.048 3 1WCM139_Z3_1 19 56228114 57081723 0.2123 0.5255 1.8613 1.0176 2 1WCM139_Z3_1 19 57085769 59083929 −0.2117 0.0189 1.0531 0.9733 1 1WCM139_Z3_1 2 41612 24107699 −0.2134 0.0168 1.0167 1.0067 1 1WCM139_Z3_1 2 24108669 42552376 0.2417 0.5596 1.9146 1.0331 2 1WCM139_Z3_1 2 42552660 44599932 0.5643 0.9276 1.9555 1.8487 2 2WCM139_Z3_1 2 44617429 45812746 0.1997 0.5109 NA NA NA NA WCM139_Z3_1 245826631 74146645 −0.2272 −2.00E−04 1.0233 0.9764 1 1 WCM139_Z3_1 274154158 75425703 0.2268 0.5424 NA NA NA NA WCM139_Z3_1 2 75425992100360602 −0.2241 0.0036 1.0532 0.9518 1 1 WCM139_Z3_1 2 100368683102644785 0.5696 0.9335 NA NA NA NA WCM139_Z3_1 2 102774221 1086086490.0399 0.3229 1.4202 1.0815 1 1 WCM139_Z3_1 2 108609470 120187509−0.2317 −0.0058 1.0181 0.9738 1 1 WCM139_Z3_1 2 120187954 1225228500.2307 0.5469 NA NA NA NA WCM139_Z3_1 2 124771732 129076090 −0.8954−0.883 1.1163 −0.0318 1 0 WCM139_Z3_1 2 130738450 133472462 −0.2788−0.0642 1.939 −0.0261 2 0 WCM139_Z3_1 2 133483232 150432976 −0.9456−0.9556 0.9988 0.0325 1 0 WCM139_Z3_1 2 150436157 153576426 −0.2417−0.0181 1.9334 0.0416 2 0 WCM139_Z3_1 2 153577013 167760399 −0.9482−0.9593 1.043 −0.0144 1 0 WCM139_Z3_1 2 167992429 171503439 −0.2314−0.0054 2.0031 −0.0106 2 0 WCM139_Z3_1 2 171508150 193059210 −0.9495−0.9612 1.0314 −0.0041 1 0 WCM139_Z3_1 2 196544880 202154564 −0.22520.0022 1.9707 0.0324 2 0 WCM139_Z3_1 2 202172299 209436747 −0.9473−0.958 1.0378 −0.0083 1 0 WCM139_Z3_1 2 210518140 212652776 −0.04440.2223 NA NA NA NA WCM139_Z3_1 2 212812152 218941184 −0.8432 −0.80881.2272 −0.0856 1 0 WCM139_Z3_1 2 218947956 219890870 0.2689 0.59111.9329 1.0798 2 1 WCM139_Z3_1 2 219892233 220497702 0.901 1.3008 3.88571.0417 4 1 WCM139_Z3_1 2 220498120 220506402 0.4966 0.8512 NA NA NA NAWCM139_Z3_1 2 220521277 234294615 −0.9522 −0.9651 0.9902 0.0343 1 0WCM139_Z3_1 2 234296984 234851280 −0.2537 −0.033 NA NA NA NA WCM139_Z3_12 234855801 242946597 −0.9464 −0.9567 1.0341 −0.0036 1 0 WCM139_Z3_1 2068375 2084004 −0.2565 −0.0365 1.0125 0.9375 1 1 WCM139_Z3_1 20 20974572473428 0.2888 0.6141 NA NA NA NA WCM139_Z3_1 20 2474188 5170848 −0.21830.0107 1.0385 0.9764 1 1 WCM139_Z3_1 20 5261132 8737771 0.3165 0.6461.7988 1.3309 2 1 WCM139_Z3_1 20 8741093 29632635 −0.2005 0.0326 1.0480.9977 1 1 WCM139_Z3_1 20 29845492 34858541 0.2733 0.5962 2.0076 1.01582 1 WCM139_Z3_1 20 35060189 35802464 0.7892 1.1779 NA NA NA NAWCM139_Z3_1 20 35807924 45362401 −0.2274 −5.00E−04 1.0355 0.9639 1 1WCM139_Z3_1 20 45618638 62904925 0.2465 0.5652 1.9939 0.9654 2 1WCM139_Z3_1 21 9826203 36422352 −0.0425 0.2246 1.4336 0.9033 1 1WCM139_Z3_1 21 37093104 39947586 0.4017 0.7436 2.1096 1.2391 2 1WCM139_Z3_1 21 40177454 44949723 −0.2397 −0.0156 1.0235 0.9549 1 1WCM139_Z3_1 21 45012126 45404974 0.2819 0.6061 NA NA NA NA WCM139_Z3_121 45432414 46101782 −0.2734 −0.0576 1.0362 0.8856 1 1 WCM139_Z3_1 2146226838 47316244 0.2161 0.5299 1.9037 0.984 2 1 WCM139_Z3_1 21 4731951248084277 −0.2579 −0.0382 1.0439 0.9038 1 1 WCM139_Z3_1 22 1628744323504959 −0.226 0.0013 1.1244 0.8773 1 1 WCM139_Z3_1 22 2352333426423602 0.4974 0.8521 2.5538 1.0566 3 1 WCM139_Z3_1 22 2656568332628995 −0.2492 −0.0274 0.9994 0.9629 1 1 WCM139_Z3_1 22 3263096637771407 0.2521 0.5717 2.0059 0.9666 2 1 WCM139_Z3_1 22 3777143742388764 −0.2674 −0.05 0.9947 0.9371 1 1 WCM139_Z3_1 22 4239034643253126 0.2296 0.5456 NA NA NA NA WCM139_Z3_1 22 43254425 51219138−0.2435 −0.0204 1.0043 0.9677 1 1 WCM139_Z3_1 3 239451 9408623 0.17930.4871 1.9105 0.8928 2 1 WCM139_Z3_1 3 9412884 11078549 −0.215 0.01481.0676 0.953 1 1 WCM139_Z3_1 3 11300891 13921258 0.2673 0.5893 1.99141.0176 2 1 WCM139_Z3_1 3 14105751 36422183 −0.2249 0.0026 1.0426 0.961 11 WCM139_Z3_1 3 36484996 38519424 0.2403 0.558 1.7777 1.1667 2 1WCM139_Z3_1 3 38519740 57835500 −0.207 0.0247 1.036 0.9985 1 1WCM139_Z3_1 3 57843458 58303759 0.2387 0.5562 NA NA NA NA WCM139_Z3_1 358318751 110611201 −0.2054 0.0266 1.05 0.9873 1 1 WCM139_Z3_1 3110611399 114833040 0.2778 0.6014 2.0883 0.9461 2 1 WCM139_Z3_1 3115382658 121168251 −0.2152 0.0146 1.04 0.9803 1 1 WCM139_Z3_1 3121178933 123987618 0.2895 0.6149 2.0612 1.0016 2 1 WCM139_Z3_1 3123987946 127642943 −0.2213 0.0071 1.0198 0.99 1 1 WCM139_Z3_1 3127646773 127981029 0.1976 0.5084 NA NA NA NA WCM139_Z3_1 3 127983495129389918 0.6334 1.0049 NA NA NA NA WCM139_Z3_1 3 129390084 1320757070.2703 0.5927 2.0309 0.9853 2 1 WCM139_Z3_1 3 132086650 135809488−0.2099 0.0211 1.0409 0.9885 1 1 WCM139_Z3_1 3 135820954 1383828510.3732 0.711 NA NA NA NA WCM139_Z3_1 3 138383917 141457251 −0.22540.0019 NA NA NA NA WCM139_Z3_1 3 141461508 149678767 0.2542 0.57411.7714 1.2061 2 1 WCM139_Z3_1 3 149678839 178525219 −0.2009 0.03221.0791 0.966 1 1 WCM139_Z3_1 3 178543436 180703742 0.2171 0.5311 NA NANA NA WCM139_Z3_1 3 180704759 183604613 −0.1978 0.036 NA NA NA NAWCM139_Z3_1 3 183639133 183993980 0.3237 0.6543 1.8559 1.2917 2 1WCM139_Z3_1 3 183994494 184580798 1.113 1.5315 4.8067 0.975 5 1WCM139_Z3_1 3 184585821 185774947 0.2285 0.5443 NA NA NA NA WCM139_Z3_13 185775243 194177886 −0.1982 0.0355 1.04 1.0098 1 1 WCM139_Z3_1 3194180267 196454862 0.2554 0.5755 1.8921 1.0884 2 1 WCM139_Z3_1 3196455044 197894726 −0.1707 0.0692 NA NA NA NA WCM139_Z3_1 4 5932736115795 −0.2176 0.0116 1.0243 0.9919 1 1 WCM139_Z3_1 4 3611868441496615 0.3382 0.6709 2.0907 1.0934 2 1 WCM139_Z3_1 4 41526470 52938245−0.2604 −0.0413 1.0333 0.9102 1 1 WCM139_Z3_1 4 52943010 57976295 0.13030.4297 1.7296 0.9642 2 1 WCM139_Z3_1 4 57976467 71471920 −0.237 −0.01241.0785 0.9044 1 1 WCM139_Z3_1 4 71472184 72121069 0.1882 0.4974 NA NA NANA WCM139_Z3_1 4 72205092 72649700 2.3897 2.8753 NA NA NA NA WCM139_Z3_14 72669661 74276042 0.8026 1.1927 NA NA NA NA WCM139_Z3_1 4 7427782178532179 0.2467 0.5654 1.9427 1.0169 2 1 WCM139_Z3_1 4 78647310 808286180.8996 1.2993 NA NA NA NA WCM139_Z3_1 4 80898758 107956693 −0.22280.0051 1.058 0.9491 1 1 WCM139_Z3_1 4 108049099 110638739 0.2936 0.6196NA NA NA NA WCM139_Z3_1 4 110650812 128544639 −0.2394 −0.0153 1.03470.9442 1 1 WCM139_Z3_1 4 128554268 130032843 0.2383 0.5557 NA NA NA NAWCM139_Z3_1 4 133357010 153273817 −0.2245 0.003 1.0565 0.9477 1 1WCM139_Z3_1 4 153303348 155665486 0.2998 0.6267 2.0581 1.03 2 1WCM139_Z3_1 4 155665792 190426502 −0.2121 0.0184 1.029 0.9966 1 1WCM139_Z3_1 5 140663 13841142 −0.2252 0.0023 1.0189 0.9843 1 1WCM139_Z3_1 5 13841860 14741984 0.3102 0.6388 NA NA NA NA WCM139_Z3_1 514746068 78077787 −0.1632 0.0784 1.0842 1.0274 1 1 WCM139_Z3_1 578111939 78532658 0.311 0.6396 2.0473 1.0686 2 1 WCM139_Z3_1 5 78532842111071153 −0.1967 0.0373 1.0476 1.0047 1 1 WCM139_Z3_1 5 111091470113831705 0.2595 0.5802 1.7649 1.2252 2 1 WCM139_Z3_1 5 113831849118456823 −0.188 0.048 NA NA NA NA WCM139_Z3_1 5 118464968 1240798770.3747 0.7127 NA NA NA NA WCM139_Z3_1 5 124080276 139819746 −0.19830.0354 1.0475 1.0022 1 1 WCM139_Z3_1 5 139820727 141059563 0.1633 0.46831.8851 0.8819 2 1 WCM139_Z3_1 5 141059868 148577925 −0.2082 0.02321.0712 0.9612 1 1 WCM139_Z3_1 5 148578655 149151698 0.3244 0.6551 NA NANA NA WCM139_Z3_1 5 149200145 154169933 −0.1856 0.0509 1.0715 1.0004 1 1WCM139_Z3_1 5 154170269 157240229 0.2537 0.5735 1.9705 1.0058 2 1WCM139_Z3_1 5 157241277 160016649 1.0334 1.4452 NA NA NA NA WCM139_Z3_15 160018106 166802458 0.4344 0.7807 NA NA NA NA WCM139_Z3_1 5 167182138168310283 0.8902 1.289 NA NA NA NA WCM139_Z3_1 5 168620527 1715337880.2467 0.5654 1.9324 1.0272 2 1 WCM139_Z3_1 5 171534801 174178774 0.55350.9154 NA NA NA NA WCM139_Z3_1 5 174868920 180687773 0.2202 0.53471.9335 0.9639 2 1 WCM139_Z3_1 6 203466 29231274 −0.2095 0.0216 1.03130.9988 1 1 WCM139_Z3_1 6 29407845 31324336 0.3211 0.6513 2.049 1.0923 21 WCM139_Z3_1 6 31540784 31685563 1.0842 1.5003 NA NA NA NA WCM139_Z3_16 31696497 34214830 0.232 0.5484 1.8579 1.0671 2 1 WCM139_Z3_1 634215247 36807104 −0.2216 0.0067 1.0195 0.9898 1 1 WCM139_Z3_1 636823622 38370599 0.2237 0.5388 1.8645 1.0411 2 1 WCM139_Z3_1 6 3845546039835367 0.6572 1.0315 3.0399 1.0483 3 1 WCM139_Z3_1 6 39835602 403597720.1888 0.4981 NA NA NA NA WCM139_Z3_1 6 40359947 43128579 −0.2096 0.02141.035 0.995 1 1 WCM139_Z3_1 6 43139725 43336706 0.3037 0.6313 NA NA NANA WCM139_Z3_1 6 43395781 43752354 0.836 1.2295 NA NA NA NA WCM139_Z3_16 43968380 46047721 0.3703 0.7077 NA NA NA NA WCM139_Z3_1 6 4610761051908440 −0.2232 0.0047 1.0677 0.9389 1 1 WCM139_Z3_1 6 5190979854219399 0.2557 0.5759 1.9719 1.0093 2 1 WCM139_Z3_1 6 54254650112443287 −0.2216 0.0066 1.1521 0.8571 1 1 WCM139_Z3_1 6 112460366118635317 0.2415 0.5594 1.8341 1.1132 2 1 WCM139_Z3_1 6 118786608143095711 −0.201 0.0321 1.069 0.976 1 1 WCM139_Z3_1 6 143382110146755515 0.2493 0.5685 1.8402 1.1257 2 1 WCM139_Z3_1 6 146755818151362942 −0.2074 0.0242 1.0319 1.0019 1 1 WCM139_Z3_1 6 151413621155764437 0.2641 0.5856 1.9761 1.0252 2 1 WCM139_Z3_1 6 155774570170893407 −0.2364 −0.0116 1.0128 0.9711 1 1 WCM139_Z3_1 7 19345137934083 −0.9728 −0.9953 0.9875 0.0157 1 0 WCM139_Z3_1 7 3793668157529300 −0.2159 0.0137 1.0307 0.9884 1 1 WCM139_Z3_1 7 5752959392404119 0.2572 0.5776 1.9691 1.0158 2 1 WCM139_Z3_1 7 92462599 985819690.8287 1.2214 3.8433 0.8202 4 1 WCM139_Z3_1 7 98582587 99590023 0.30060.6276 1.9366 1.1535 2 1 WCM139_Z3_1 7 99621300 100410718 0.9849 1.39254.0867 1.1639 4 1 WCM139_Z3_1 7 100411638 100683439 0.661 1.0357 2.84061.2596 3 1 WCM139_Z3_1 7 100683721 105132022 0.8834 1.2815 3.9477 0.91434 1 WCM139_Z3_1 7 105135645 134576402 0.2623 0.5835 1.9699 1.0271 2 1WCM139_Z3_1 7 134605465 135255861 0.9346 1.3375 NA NA NA NA WCM139_Z3_17 135258537 142760171 0.3345 0.6667 2.0211 1.1538 2 1 WCM139_Z3_1 7142829266 150069209 −0.2492 −0.0275 1.9695 −0.0072 2 0 WCM139_Z3_1 7150069438 158937066 −0.9626 −0.9803 1.0229 −0.0092 1 0 WCM139_Z3_1 8190908 677159 0.3452 0.6789 NA NA NA NA WCM139_Z3_1 8 681156 32537230.6077 0.9762 NA NA NA NA WCM139_Z3_1 8 3256976 33347834 0.2465 0.56531.9802 0.9791 2 1 WCM139_Z3_1 8 33353077 37791982 0.8833 1.2814 3.90730.9542 4 1 WCM139_Z3_1 8 37792528 41166670 0.2617 0.5828 NA NA NA NAWCM139_Z3_1 8 41293113 51617255 0.7505 1.1351 2.3835 2.0091 2 2WCM139_Z3_1 8 51621461 59059865 0.2658 0.5876 1.9753 1.0302 2 1WCM139_Z3_1 8 59324028 66963858 0.8344 1.2277 NA NA NA NA WCM139_Z3_1 866989039 73157129 1.225 1.6522 5.2236 1.0624 5 1 WCM139_Z3_1 8 7348012981605342 0.8303 1.2232 3.6115 1.0577 4 1 WCM139_Z3_1 8 81733706 948275530.2464 0.565 1.9628 0.9961 2 1 WCM139_Z3_1 8 94928335 97621725 0.91681.3181 NA NA NA NA WCM139_Z3_1 8 97797247 114627762 0.2671 0.5891 1.90941.0991 2 1 WCM139_Z3_1 8 116426469 125877519 0.9125 1.3134 4.0191 0.95124 1 WCM139_Z3_1 8 125987895 146279507 0.2715 0.5941 1.9822 1.0369 2 1WCM139_Z3_1 9 17083 93376085 −0.218 0.0111 1.0338 0.9816 1 1 WCM139_Z3_19 93606196 96326824 0.565 0.9283 1.9479 1.8581 2 2 WCM139_Z3_1 996357172 129961296 −0.2288 −0.0022 1.0207 0.9763 1 1 WCM139_Z3_1 9129972982 134165505 0.2485 0.5676 1.9919 0.9722 2 1 WCM139_Z3_1 9134165753 136726500 0.6488 1.0221 3.0662 0.9956 3 1 WCM139_Z3_1 9136804303 139221397 0.2236 0.5387 1.8947 1.0106 2 1 WCM139_Z3_1 9139221680 141111414 −0.2168 0.0126 1.0262 0.9914 1 1 WCM139_Z3_1 X2707682 15536060 0.4279 0.7734 NA NA NA NA WCM139_Z3_1 X 1554058521959443 −0.212 0.0184 NA NA NA NA WCM139_Z3_1 X 21985429 22186450 0.6721.048 NA NA NA NA WCM139_Z3_1 X 22196409 48435890 −0.1521 0.0919 NA NANA NA WCM139_Z3_1 X 48542706 48979985 0.5865 0.9524 NA NA NA NAWCM139_Z3_1 X 49021073 64771929 −0.3307 −0.1291 NA NA NA NA WCM139_Z3_1X 64949319 67751772 0.8931 1.2922 NA NA NA NA WCM139_Z3_1 X 6786773383141570 −0.2446 −0.0218 NA NA NA NA WCM139_Z3_1 X 83319369 834807940.6884 1.0662 NA NA NA NA WCM139_Z3_1 X 83581254 96396740 −0.2765−0.0614 NA NA NA NA WCM139_Z3_1 X 96603225 100494055 0.5952 0.9622 NA NANA NA WCM139_Z3_1 X 100496661 108926521 −0.2085 0.0228 NA NA NA NAWCM139_Z3_1 X 109247203 118513924 0.5005 0.8557 NA NA NA NA WCM139_Z3_1X 118540552 132458553 −0.2689 −0.0519 NA NA NA NA WCM139_Z3_1 X132473353 135047187 0.497 0.8517 NA NA NA NA WCM139_Z3_1 X 135049578154509348 −0.2643 −0.0462 NA NA NA NA WCM142 1 14930 24859663 0.01710.1212 1.1883 0.9869 1 1 WCM142 1 24861593 151258901 −0.0541 −1.05470.4814 0.4814 0 0 WCM142 1 151259562 249214018 0.0466 0.431 1.34821.3482 1 1 WCM142 10 226048 135477898 −0.0067 −0.1815 0.8818 0.8818 1 1WCM142 11 193096 134605906 0.0412 0.378 1.2995 1.2995 1 1 WCM142 12148427 133810703 0.0034 −0.0459 0.9687 0.9687 1 1 WCM142 13 19041992115089411 −0.0387 −0.7135 0.6098 0.6098 1 1 WCM142 14 19110343 1072832550.0175 0.1261 1.0913 1.0913 1 1 WCM142 15 20083896 102514200 0.0053−0.0219 0.9849 0.9849 1 1 WCM142 16 64401 90168646 −4.00E−04 −0.09470.9365 0.9365 1 1 WCM142 17 131595 1183426 0.0216 0.1729 1.3799 0.8748 11 WCM142 17 1183637 8457234 −0.1189 NA −0.0443 −0.0443 0 0 WCM142 178464687 81187891 0.0103 0.041 1.0289 1.0289 1 1 WCM142 18 47610 78005210−0.0637 −1.3143 0.4021 0.4021 0 0 WCM142 19 105041 59093696 0.02350.1938 1.1438 1.1438 1 1 WCM142 2 41620 243037022 0.0026 −0.0557 0.96210.9621 1 1 WCM142 20 68346 62934572 0.0234 0.1926 1.1428 1.1428 1 1WCM142 21 9590271 48084142 0.0205 0.1601 1.1174 1.1174 1 1 WCM142 2216159016 51219138 0.0481 0.445 1.3613 1.3613 1 1 WCM142 3 239530197896798 0.0243 0.2022 1.1505 1.1505 1 1 WCM142 4 53423 1908785080.0058 −0.0154 0.9894 0.9894 1 1 WCM142 5 90680 180687804 −0.0532−1.0313 0.4893 0.4893 0 0 WCM142 6 203475 170892848 0.0012 −0.0741 0.950.95 1 1 WCM142 7 193171 158937227 0.0505 0.4673 1.3825 1.3825 1 1WCM142 8 163432 48689570 −0.0482 −0.913 0.5311 0.5311 1 1 WCM142 848690289 145948719 0.1067 0.9219 1.8946 1.8946 2 2 WCM142 8 145979138146279431 −0.0665 −1.3993 NA NA NA NA WCM142 9 14893 141107519 0.05020.4643 1.3796 1.3796 1 1 WCM142 X 2700145 154493609 0.0364 0.3306 NA NANA NA WCM14-TP1 1 762088 108724658 −0.1074 0.8827 2.3593 1.3285 2 1WCM14-TP1 1 108728589 111216659 −0.6427 0.1247 1.9861 0.1944 2 0WCM14-TP1 1 111217007 193099372 −0.1944 0.7669 2.1823 1.2209 2 1WCM14-TP1 1 193104708 208062471 0.2764 1.3701 3.067 2.1027 3 2 WCM14-TP11 208062973 249212577 −0.1768 0.7906 2.2279 1.2316 2 1 WCM14-TP1 10386619 45938452 0.1351 1.1946 2.539 2.0386 3 2 WCM14-TP1 10 4598487870516035 −0.33 0.5814 1.8213 1.1712 2 1 WCM14-TP1 10 70517064 811135860.5454 1.6937 3.9765 2.4934 4 2 WCM14-TP1 10 81145992 135053877 −0.4950.346 2.3489 0.1932 2 0 WCM14-TP1 10 135061128 135379000 −0.0389 0.97242.6963 1.2279 3 1 WCM14-TP1 11 193096 1026393 0.154 1.2183 3.7634 0.89014 1 WCM14-TP1 11 1027089 4410925 0.095 1.144 3.5247 0.8952 4 1 WCM14-TP111 4411334 6942748 −0.7634 −0.0655 1.7872 0.124 2 0 WCM14-TP1 11 694325847350681 −0.1479 0.8291 2.9821 0.571 3 1 WCM14-TP1 11 47350876 134257753−0.0293 0.9848 2.7567 1.2015 3 1 WCM14-TP1 12 247582 4854809 0.05971.0992 2.4181 1.8667 2 2 WCM14-TP1 12 4855365 38712138 −0.3061 0.61462.0861 0.9761 2 1 WCM14-TP1 12 38712265 92538251 0.0075 1.0323 2.19011.9005 2 2 WCM14-TP1 12 92539243 133810751 0.5683 1.7208 4.1194 2.4729 42 WCM14-TP1 13 19601063 45841502 −0.6186 0.1616 2.0499 0.1871 2 0WCM14-TP1 13 45857737 111099057 −1.164 −0.7821 1.0864 0.0766 1 0WCM14-TP1 13 111102042 115089411 −0.3529 0.5493 2.7 0.2268 3 0 WCM14-TP114 19110188 20296498 1.0002 2.2177 7.8365 1.4663 8 1 WCM14-TP1 1420344415 100119096 0.1216 1.1776 2.4957 2.0284 2 2 WCM14-TP1 14100123516 107283269 0.4812 1.6176 3.383 2.7542 3 3 WCM14-TP1 15 2008760525287234 −0.4946 0.3467 1.7252 0.8181 2 1 WCM14-TP1 15 25523590102389659 −0.53 0.2946 1.4914 0.9617 1 1 WCM14-TP1 16 97605 299127940.1316 1.1902 2.6118 1.9519 3 2 WCM14-TP1 16 29912970 80584342 −0.3670.5295 1.7501 1.1368 2 1 WCM14-TP1 16 80638455 81697861 −0.9929 −0.45671.2248 0.2325 1 0 WCM14-TP1 16 81703861 85697023 −0.4428 0.4218 1.63831.0409 2 1 WCM14-TP1 16 85697189 90168697 0.0309 1.0625 2.6397 1.5373 32 WCM14-TP1 17 131595 5462581 0.2155 1.2949 2.8246 2.0826 3 2 WCM14-TP117 5463034 21207909 −0.5753 0.2271 2.1425 0.1984 2 0 WCM14-TP1 1721208317 81052332 0.1413 1.2024 2.6276 1.9748 3 2 WCM14-TP1 18 4766921116858 −0.0181 0.9994 2.5915 1.4069 3 1 WCM14-TP1 18 21118575 78005164−0.6538 0.1075 2.0129 0.1418 2 0 WCM14-TP1 19 281543 7998998 −0.26320.6736 2.9481 0.242 3 0 WCM14-TP1 19 8000001 8987271 0.0071 1.03192.6079 1.4814 3 1 WCM14-TP1 19 8993027 9033814 1.7257 3.0134 8.99297.1566 9 7 WCM14-TP1 19 9038114 11687709 0.0965 1.146 2.4622 1.9638 2 2WCM14-TP1 19 12761041 19774034 0.1011 1.1518 2.6433 1.8005 3 2 WCM14-TP119 19779736 30498329 1.3536 2.6102 6.1728 6.0389 6 6 WCM14-TP1 1930499976 52794204 0.1101 1.1631 2.5333 1.9454 3 2 WCM14-TP1 19 5279443054307360 1.6865 2.9714 7.9103 7.7754 8 8 WCM14-TP1 19 54308554 590630880.1743 1.2437 2.7021 2.0342 3 2 WCM14-TP1 2 41463 84851763 −0.196 0.76472.1952 1.2029 2 1 WCM14-TP1 2 84852135 179363945 −0.1459 0.8318 2.02611.5337 2 2 WCM14-TP1 2 179365928 179646981 −0.8849 −0.2672 0.8522 0.80971 1 WCM14-TP1 2 179647305 238462324 −0.2235 0.7276 1.8421 1.4697 2 1WCM14-TP1 2 238475353 242946604 −0.0271 0.9877 2.4996 1.4664 2 1WCM14-TP1 20 68299 30053478 0.1258 1.183 2.5734 1.9675 3 2 WCM14-TP1 2030060755 56186831 −0.3452 0.5601 1.8785 1.0703 2 1 WCM14-TP1 20 5618827362905001 0.0754 1.1192 2.9476 1.3968 3 1 WCM14-TP1 21 9907274 144149290.6919 1.8653 5.2722 2.0146 5 2 WCM14-TP1 21 14418567 17138408 −1.1175−0.6902 1.385 −0.1455 1 0 WCM14-TP1 21 17150327 48084142 0.1642 1.23112.6291 2.0657 3 2 WCM14-TP1 22 17052984 51219090 −0.1749 0.793 3.24070.2247 3 0 WCM14-TP1 3 239390 7678056 0.313 1.4149 3.1057 2.2272 3 2WCM14-TP1 3 7721890 16216844 −0.5079 0.3271 2.4314 0.0776 2 0 WCM14-TP13 16217040 33093489 0.3685 1.4822 2.8817 2.7059 3 3 WCM14-TP1 3 3309512137369939 −0.4611 0.3954 1.77 0.8606 2 1 WCM14-TP1 3 37370562 455833320.4014 1.522 3.1971 2.5468 3 3 WCM14-TP1 3 45588967 53925849 −0.50430.3325 2.3116 0.2067 2 0 WCM14-TP1 3 54157554 59997166 0.6386 1.80333.535 3.4453 4 3 WCM14-TP1 3 59999668 89528659 −0.3188 0.5969 2.99290.0321 3 0 WCM14-TP1 3 90255162 113440586 0.0064 1.031 2.0697 2.0171 2 2WCM14-TP1 3 125701243 182631792 0.2151 1.2945 2.6201 2.2857 3 2WCM14-TP1 3 182631831 184144822 −0.1771 0.7902 2.2297 1.2289 2 1WCM14-TP1 3 184157036 197847453 0.2064 1.2837 2.4587 2.4104 2 2WCM14-TP1 4 53446 48581017 −0.1604 0.8124 2.253 1.2593 2 1 WCM14-TP1 448581297 72631387 0.3462 1.4552 2.7653 2.7187 3 3 WCM14-TP1 4 7401045985648096 0.0563 1.0949 2.8086 1.4633 3 1 WCM14-TP1 4 85654497 141330994−0.3676 0.5287 1.875 1.0102 2 1 WCM14-TP1 4 141331746 187203041 −0.04040.9704 2.079 1.8397 2 2 WCM14-TP1 5 140696 50074439 0.3313 1.4372 2.85952.5563 3 3 WCM14-TP1 5 50084313 180687828 −0.2777 0.6537 2.999 0.1473 30 WCM14-TP1 6 203552 62687960 −0.2763 0.6556 2.0338 1.1168 2 1 WCM14-TP16 69685114 109980643 −0.2584 0.6801 2.0336 1.1709 2 1 WCM14-TP1 6109982120 134303661 −0.0354 0.9769 2.7451 1.1914 3 1 WCM14-TP1 6134303921 149285680 −0.3466 0.5582 1.6825 1.2623 2 1 WCM14-TP1 6149340390 152675990 −1.1431 −0.7404 1.0788 0.1183 1 0 WCM14-TP1 6152679647 160219189 −0.4253 0.4468 1.9072 0.8189 2 1 WCM14-TP1 6160221442 161162406 0.7195 1.8973 4.0357 3.4147 4 3 WCM14-TP1 6161173313 170892853 −0.3963 0.4881 2.1847 0.6206 2 1 WCM14-TP1 7 1955796661628 0.1071 1.1594 2.8825 1.5848 3 2 WCM14-TP1 7 6662314 36463419−0.2895 0.6374 1.8791 1.2319 2 1 WCM14-TP1 7 36464274 158937375 0.23511.3192 2.9485 2.0422 3 2 WCM14-TP1 8 190850 43027457 −0.574 0.22912.1626 0.1816 2 0 WCM14-TP1 8 43028897 146279489 0.8697 2.0698 6.05532.3415 6 2 WCM14-TP1 9 214535 17502798 −1.1212 −0.6974 1.1452 0.0881 1 0WCM14-TP1 9 17747173 21968256 0.518 1.6614 6.2086 0.1178 6 0 WCM14-TP1 921968695 32784695 −0.2596 0.6785 3.0618 0.139 3 0 WCM14-TP1 9 3278500669830308 0.0536 1.0915 2.3892 1.8727 2 2 WCM14-TP1 9 71144551 141016359−0.1153 0.8723 3.4577 0.2033 3 0 WCM14-TP1 X 2700166 65835817 0.77271.9588 NA NA NA NA WCM14-TP1 X 66765138 68060476 2.6185 3.9539 NA NA NANA WCM14-TP1 X 68381246 92965154 −0.643 0.1242 NA NA NA NA WCM14-TP1 X94318093 154275641 0.1216 1.1777 NA NA NA NA WCM14-TP1 X 154282988154509348 −0.7932 −0.1139 NA NA NA NA WCM14-TP2 1 762244 108307731−0.0902 0.837 2.3135 1.2591 2 1 WCM14-TP2 1 108309202 111773600 −0.53030.1715 1.9589 0.2936 2 0 WCM14-TP2 1 111773882 197480029 −0.1288 0.78242.1306 1.3094 2 1 WCM14-TP2 1 197481015 207958406 0.3417 1.4127 3.05522.2696 3 2 WCM14-TP2 1 207959070 249212589 −0.1645 0.7315 2.0609 1.25972 1 WCM14-TP2 10 226083 45938452 0.1675 1.1873 2.3342 2.2202 2 2WCM14-TP2 10 45984844 70502209 −0.2999 0.5327 1.7441 1.1493 2 1WCM14-TP2 10 70502336 81343131 0.5978 1.7313 4.0118 2.6286 4 3 WCM14-TP210 81372081 135101582 −0.4862 0.2434 2.2045 0.163 2 0 WCM14-TP2 10135101839 135378985 −0.0581 0.8819 3.3034 0.3822 3 0 WCM14-TP2 11 1930964159719 0.0211 0.991 3.4248 0.5504 3 1 WCM14-TP2 11 4185612 7067950−0.7247 −0.1633 1.8325 −0.0466 2 0 WCM14-TP2 11 7068117 43852491 −0.1190.7963 3.0531 0.4201 3 0 WCM14-TP2 11 43859820 134257738 0.0201 0.98972.8231 1.1484 3 1 WCM14-TP2 12 247582 313816 0.8612 2.0463 NA NA NA NAWCM14-TP2 12 319111 4854828 0.1147 1.1173 2.2099 2.1289 2 2 WCM14-TP2 124855365 28122893 −0.2362 0.6273 2.1074 0.982 2 1 WCM14-TP2 12 2841014649496723 −0.0123 0.9453 1.9785 1.8725 2 2 WCM14-TP2 12 49496978 534430610.3525 1.4265 2.7186 2.6572 3 3 WCM14-TP2 12 53443982 91502602 0.00250.9656 1.9689 1.9368 2 2 WCM14-TP2 12 91502721 133810751 0.6377 1.77984.307 2.5607 4 3 WCM14-TP2 13 19601109 45915151 −0.5798 0.0893 1.99370.1341 2 0 WCM14-TP2 13 45970090 110408608 −1.1189 −0.9817 0.9814 0.03141 0 WCM14-TP2 13 110434474 115089411 −0.3301 0.4873 2.4435 0.3601 2 0WCM14-TP2 14 19110188 107283269 0.178 1.2011 2.4564 2.142 2 2 WCM14-TP215 20087605 25287198 −0.4054 0.3714 1.8183 0.769 2 1 WCM14-TP2 1525296754 25495991 1.8014 3.1028 NA NA NA NA WCM14-TP2 15 25514925102389685 −0.529 0.1737 1.2798 0.976 1 1 WCM14-TP2 16 97423 339615530.1246 1.1305 2.4283 1.9505 2 2 WCM14-TP2 16 33965589 79632669 −0.42440.3416 1.4364 1.0979 1 1 WCM14-TP2 16 79632894 82197704 −0.9422 −0.58491.0686 0.2647 1 0 WCM14-TP2 16 82203705 89735933 −0.2522 0.6038 1.75981.2796 2 1 WCM14-TP2 16 89753225 90168687 −0.0978 0.8263 1.913 1.6333 22 WCM14-TP2 17 131595 5462349 0.2042 1.2355 2.407 2.3023 2 2 WCM14-TP217 5462627 21201719 −0.5638 0.1161 2.0927 0.075 2 0 WCM14-TP2 1721201851 81052303 0.1656 1.1848 2.519 2.0275 3 2 WCM14-TP2 18 4766819444692 0.0053 0.9694 2.4086 1.5074 2 2 WCM14-TP2 18 19751212 78005215−0.565 0.1141 2.0595 0.105 2 0 WCM14-TP2 19 281405 7990225 −0.35540.4486 2.5283 0.2012 3 0 WCM14-TP2 19 7992052 8982235 0.305 1.36592.6665 2.4882 3 2 WCM14-TP2 19 8987127 9038066 1.8683 3.1752 9.55038.516 10  9 WCM14-TP2 19 9038331 11687654 0.0736 1.0623 2.1051 2.0714 22 WCM14-TP2 19 11688130 12576173 1.4268 2.6917 NA NA NA NA WCM14-TP2 1912576453 19843548 0.1484 1.1621 2.2586 2.2171 2 2 WCM14-TP2 19 1984381030020678 1.5574 2.8362 7.3066 6.9762 7 7 WCM14-TP2 19 30021023 527938780.1783 1.2015 2.3482 2.2514 2 2 WCM14-TP2 19 52794291 54304483 1.7853.085 8.4855 8.4855 8 8 WCM14-TP2 19 54307249 59083951 0.225 1.26262.4336 2.3649 2 2 WCM14-TP2 2 41612 86357774 −0.1457 0.7583 2.19881.1842 2 1 WCM14-TP2 2 86358285 179367086 −0.1335 0.7758 1.9948 1.4295 21 WCM14-TP2 2 179391834 179647077 −0.7374 −0.1864 1.0182 0.7393 1 1WCM14-TP2 2 179647314 242590329 −0.1554 0.7445 1.8937 1.457 2 1WCM14-TP2 2 242590775 242946657 −0.1567 0.7426 1.8027 1.5437 2 2WCM14-TP2 20 68375 25448025 0.1369 1.1468 2.2348 2.1936 2 2 WCM14-TP2 2025450742 30897493 −0.124 0.7892 2.5031 0.9532 3 1 WCM14-TP2 20 3089788341101170 −0.4352 0.3247 1.2959 1.2089 1 1 WCM14-TP2 20 41306600 56275268−0.2379 0.6248 1.9748 1.1091 2 1 WCM14-TP2 20 56284586 62905001 0.08221.0738 2.7388 1.4713 3 1 WCM14-TP2 21 9907274 14414913 0.4233 1.51583.9527 1.7666 4 2 WCM14-TP2 21 14418567 16340289 −0.8351 −0.3699 1.5543−0.0066 2 0 WCM14-TP2 21 16340454 48084142 0.1983 1.2278 2.3635 2.3206 22 WCM14-TP2 22 17052984 51219089 −0.1556 0.7443 3.1579 0.1924 3 0WCM14-TP2 3 239524 7678056 0.3205 1.3858 2.7199 2.5063 3 3 WCM14-TP2 37721826 16216760 −0.4749 0.2615 2.2159 0.1815 2 0 WCM14-TP2 3 1621707933093505 0.3197 1.3848 2.6913 2.5312 3 3 WCM14-TP2 3 33095121 37369294−0.3555 0.4485 1.6863 1.0429 2 1 WCM14-TP2 3 37369984 45714194 0.33851.4087 2.8644 2.4454 3 2 WCM14-TP2 3 45715065 49701108 −0.7041 −0.12611.83 0.0026 2 0 WCM14-TP2 3 49701298 52722099 −0.3127 0.5134 1.52641.3285 2 1 WCM14-TP2 3 52723268 53925849 −0.6576 −0.044 1.8408 0.0992 20 WCM14-TP2 3 54157497 61911540 0.5926 1.725 3.3903 3.2211 3 3 WCM14-TP23 61975520 90264953 −0.1864 0.6999 3.2308 0.018 3 0 WCM14-TP2 3 90274768113392205 0.0796 1.0703 2.1083 2.0914 2 2 WCM14-TP2 3 113393740125694511 −0.5425 0.1515 NA NA NA NA WCM14-TP2 3 125701277 1836964020.2347 1.2753 2.4424 2.3984 2 2 WCM14-TP2 3 183699421 184003328 −0.34880.4587 1.6849 1.0638 2 1 WCM14-TP2 3 184005619 197847416 0.1987 1.22832.3614 2.3246 2 2 WCM14-TP2 4 53446 55593685 −0.1581 0.7406 2.17851.1631 2 1 WCM14-TP2 4 55594073 72622601 0.4247 1.5175 2.8809 2.845 3 3WCM14-TP2 4 72623766 74008518 −0.3021 0.5295 NA NA NA NA WCM14-TP2 474010439 85648072 0.1647 1.1836 2.8766 1.6664 3 2 WCM14-TP2 4 85654688141560576 −0.3089 0.5193 1.7935 1.073 2 1 WCM14-TP2 4 141563742187188343 0.0284 1.001 2.0096 1.9932 2 2 WCM14-TP2 4 187192933 190862042−0.6666 −0.0597 NA NA NA NA WCM14-TP2 5 140603 44388817 0.3756 1.45582.7777 2.7084 3 3 WCM14-TP2 5 44809120 180687847 −0.2249 0.6439 2.96210.1631 3 0 WCM14-TP2 6 203546 62442604 −0.1825 0.7056 2.0217 1.2399 2 1WCM14-TP2 6 62604611 69348586 −1.3488 −1.621 NA NA NA NA WCM14-TP2 669348859 148852745 −0.1547 0.7454 2.1854 1.1675 2 1 WCM14-TP2 6148854058 152660451 −1.0228 −0.7585 1.1212 0.0611 1 0 WCM14-TP2 6152665261 159686065 −0.3939 0.3892 1.871 0.7484 2 1 WCM14-TP2 6159687149 166580358 0.2077 1.24 2.7447 1.9794 3 2 WCM14-TP2 6 166581034170892873 −0.51 0.2047 2.1245 0.1804 2 0 WCM14-TP2 7 193346 1518526−0.0067 0.953 NA NA NA NA WCM14-TP2 7 1519056 38259291 −0.1342 0.77472.1175 1.3042 2 1 WCM14-TP2 7 38268395 38785245 0.279 1.3325 2.72922.3077 3 2 WCM14-TP2 7 38791843 39874024 1.5625 2.8418 NA NA NA NAWCM14-TP2 7 39990283 56183977 0.1036 1.1024 2.5061 1.7882 3 2 WCM14-TP27 56358862 65552703 1.5709 2.8511 7.7078 6.7233 8 7 WCM14-TP2 7 65553833158937357 0.2374 1.2787 2.7507 2.1017 3 2 WCM14-TP2 8 190912 43046564−0.5288 0.174 2.1191 0.1372 2 0 WCM14-TP2 8 43047497 146279479 0.93532.1329 6.2974 2.4749 6 2 WCM14-TP2 9 214597 17502798 −0.999 −0.7061.1292 0.0969 1 0 WCM14-TP2 9 17579296 20981684 0.7714 1.9402 7.50520.17 8 0 WCM14-TP2 9 20982416 32541894 −0.1723 0.7202 3.2103 0.0846 3 0WCM14-TP2 9 32542204 71225850 −7.00E−04 0.9612 2.2808 1.6131 2 2WCM14-TP2 9 71395145 141016459 −0.0745 0.859 3.4532 0.1743 3 0 WCM14-TP2X 2700108 65835822 0.8077 1.9832 NA NA NA NA WCM14-TP2 X 6676503368060461 2.5993 3.9514 NA NA NA NA WCM14-TP2 X 68381264 96140046 −0.57020.1055 NA NA NA NA WCM14-TP2 X 96167471 154509348 0.1475 1.1608 NA NA NANA WCM14-TP3 1 762244 109177786 −0.0938 0.8271 2.4313 1.1169 2 1WCM14-TP3 1 109191376 111785067 −0.4183 −0.0788 1.7866 0.1071 2 0WCM14-TP3 1 111824318 152185500 −0.1378 0.7231 2.1647 1.1368 2 1WCM14-TP3 1 152185767 152328479 1.2979 3.0779 9.349 7.5385 9 8 WCM14-TP31 152328908 201020105 −0.0992 0.8145 2.2703 1.2472 2 1 WCM14-TP3 1201021692 206651179 0.3299 1.6673 3.2422 3.11 3 3 WCM14-TP3 1 206651624249212760 −0.1254 0.7527 2.3279 1.0421 2 1 WCM14-TP3 10 225982 70514563−0.003 1.0292 2.4127 1.6691 2 2 WCM14-TP3 10 70515093 81113488 0.48991.9345 4.6781 2.9668 5 3 WCM14-TP3 10 81145992 135279810 −0.3057 0.27862.3478 0.0782 2 0 WCM14-TP3 10 135280765 135378971 0.2469 1.5201 NA NANA NA WCM14-TP3 11 193096 1031238 −0.0168 0.9995 3.3944 0.6042 3 1WCM14-TP3 11 1031814 4408265 0.1521 1.3433 4.1836 0.8911 4 1 WCM14-TP311 4409527 7065086 −0.7423 −1.8014 1.2695 −0.6957 1 −1  WCM14-TP3 117067929 43852491 −0.0876 0.8414 3.1118 0.4717 3 0 WCM14-TP3 11 43859976134257753 −0.0484 0.9301 2.732 1.0789 3 1 WCM14-TP3 12 247582 45435740.1144 1.27 2.5397 2.2835 3 2 WCM14-TP3 12 4553391 40631959 −0.09670.8203 2.438 1.0935 2 1 WCM14-TP3 12 40634388 92538265 0.0209 1.07992.1361 2.0916 2 2 WCM14-TP3 12 92539254 133770121 0.4861 1.9284 4.63522.9775 5 3 WCM14-TP3 12 133778796 133810935 −0.4409 −0.1588 NA NA NA NAWCM14-TP3 13 19601153 45841502 −0.3725 0.074 2.1158 −0.0106 2 0WCM14-TP3 13 45857595 110895092 −0.7717 −2.0951 0.6962 −0.2281 1 0WCM14-TP3 13 110959368 115089411 −0.1113 0.7862 3.1489 0.3002 3 0WCM14-TP3 14 19110188 107283270 0.1095 1.2605 2.6417 2.1498 3 2WCM14-TP3 15 20087605 25287205 −0.1645 0.6577 2.4223 0.7328 2 1WCM14-TP3 15 25296735 25515021 2.3115 4.2798 NA NA NA NA WCM14-TP3 1525523593 102389747 −0.355 0.1294 1.3441 0.8437 1 1 WCM14-TP3 16 9751528916320 0.1456 1.3309 2.7871 2.244 3 2 WCM14-TP3 16 28916759 85696657−0.2769 0.3611 1.6896 0.8792 2 1 WCM14-TP3 16 85697100 90168701 0.08031.2023 2.681 1.921 3 2 WCM14-TP3 17 131595 5433341 0.1327 1.3058 2.55392.3905 3 2 WCM14-TP3 17 5433941 21730703 −0.4493 −0.1893 1.9044 −0.15032 0 WCM14-TP3 17 21825435 81052303 0.1205 1.2821 2.6941 2.1699 3 2WCM14-TP3 18 47661 20573029 0.0395 1.1189 2.6989 1.6447 3 2 WCM14-TP3 1820573217 74680114 −0.4045 −0.0316 1.9817 −0.0251 2 0 WCM14-TP3 1874692281 78005150 −0.2208 0.514 NA NA NA NA WCM14-TP3 19 281435 7992625−0.2376 0.4693 2.5741 0.1948 3 0 WCM14-TP3 19 7992959 8987187 0.18381.4036 2.7303 2.561 3 3 WCM14-TP3 19 8993008 9027274 1.9636 3.883916.6952 12.8313 17  13  WCM14-TP3 19 9027623 11688156 0.0589 1.15882.2783 2.187 2 2 WCM14-TP3 19 11708464 12576269 1.1582 2.8971 NA NA NANA WCM14-TP3 19 12576371 19843634 0.037 1.1136 2.2089 2.1189 2 2WCM14-TP3 19 19905342 30020678 1.4624 3.2848 10.0598 9.4317 10  9WCM14-TP3 19 30020992 52794022 0.0493 1.139 2.4517 1.9528 2 2 WCM14-TP319 52794243 54301537 1.4193 3.2312 9.484 9.2964 9 9 WCM14-TP3 1954304572 59083923 0.1188 1.2788 2.5692 2.2836 3 2 WCM14-TP3 2 41602179341953 −0.1156 0.776 2.1574 1.2674 2 1 WCM14-TP3 2 179343217186678786 −0.6198 −0.9457 0.5534 0.4849 1 0 WCM14-TP3 2 186680141189874873 −0.0493 0.9281 1.9748 1.8307 2 2 WCM14-TP3 2 189875382234098481 −0.0998 0.8131 1.7939 1.7202 2 2 WCM14-TP3 2 234102624242946531 −0.0258 0.9798 2.4803 1.4642 2 1 WCM14-TP3 20 68351 3218127−0.1542 0.6833 1.783 1.4285 2 1 WCM14-TP3 20 3218634 25448091 0.1461.3317 2.5606 2.4733 3 2 WCM14-TP3 20 25450682 62905001 −0.1528 0.68652.0667 1.152 2 1 WCM14-TP3 21 9907274 48084196 0.1343 1.309 2.52572.4295 3 2 WCM14-TP3 22 17052984 51219090 −0.1119 0.7849 3.3617 0.0842 30 WCM14-TP3 3 239495 7728097 0.1329 1.3062 2.9102 2.0355 3 2 WCM14-TP3 37732961 16216961 −0.26 0.4083 2.5717 0.0826 3 0 WCM14-TP3 3 1621714545714211 0.2184 1.4681 2.9246 2.6084 3 3 WCM14-TP3 3 45714902 49040173−0.3822 0.0425 2.1936 −0.1338 2 0 WCM14-TP3 3 49042344 49720779 −1.0777NA 0.4039 −0.917 0 −1  WCM14-TP3 3 49728896 53925849 −0.272 0.375 2.53470.0589 3 0 WCM14-TP3 3 54157639 61975493 0.4941 1.9413 3.9639 3.7169 4 4WCM14-TP3 3 61989192 75378434 −0.192 0.5885 3.0577 −0.0503 3 0 WCM14-TP33 75378546 113376954 0.0363 1.1122 2.2112 2.1123 2 2 WCM14-TP3 3113377361 125271511 −0.412 −0.0571 1.5245 0.3978 2 0 WCM14-TP3 3125272968 197847416 0.1299 1.3003 2.7267 2.1991 3 2 WCM14-TP3 4 5344655133936 −0.1267 0.7498 2.1473 1.2159 2 1 WCM14-TP3 4 55136853 728978680.2997 1.6145 3.1214 3.0027 3 3 WCM14-TP3 4 72934632 190862042 −0.12580.752 2.0256 1.3426 2 1 WCM14-TP3 5 140637 44388956 0.2971 1.6099 3.08473.02 3 3 WCM14-TP3 5 44809186 140731357 −0.1776 0.6251 3.1081 −0.0235 30 WCM14-TP3 5 140731451 141337225 −0.6936 −1.4075 1.7457 −0.9917 2 −1 WCM14-TP3 5 141353338 180687821 −0.1852 0.6058 3.0832 −0.0395 3 0WCM14-TP3 6 203428 150464488 −0.178 0.6241 2.0643 1.0181 2 1 WCM14-TP3 6150535957 152675994 −0.9304 NA 0.4405 −0.5071 0 −1  WCM14-TP3 6152679571 170892853 −0.122 0.761 2.464 0.9253 2 1 WCM14-TP3 7 1933594780430 0.1474 1.3343 3.1721 1.871 3 2 WCM14-TP3 7 4780658 36571999−0.0927 0.8296 2.2581 1.2963 2 1 WCM14-TP3 7 36580045 56183977 0.17061.3787 3.1529 2.0478 3 2 WCM14-TP3 7 56358862 64441754 1.6636 3.530212.1779 10.9281 12  11  WCM14-TP3 7 64451558 158937361 0.2185 1.46813.3327 2.2005 3 2 WCM14-TP3 8 190907 43027457 −0.3798 0.0501 2.1167−0.046 2 0 WCM14-TP3 8 43028806 144650332 0.7634 2.3526 7.3618 2.8528 73 WCM14-TP3 8 144651821 145750114 0.0908 1.2232 4.328 0.3415 4 0WCM14-TP3 8 145753014 146279529 0.6529 2.1886 NA NA NA NA WCM14-TP3 9214494 17579270 −0.6452 −1.0911 0.9907 −0.0519 1 0 WCM14-TP3 9 1774717321968293 0.4914 1.9369 7.1997 0.4582 7 0 WCM14-TP3 9 21968678 33473846−0.1921 0.5884 2.881 0.1261 3 0 WCM14-TP3 9 33528813 34088551 0.59462.0996 NA NA NA NA WCM14-TP3 9 34089395 74562066 −0.1874 0.6002 1.61221.4197 2 1 WCM14-TP3 9 74586468 141016451 −0.0317 0.9671 3.8117 0.0981 40 WCM14-TP3 X 2700159 65835841 0.6025 2.1117 NA NA NA NA WCM14-TP3 X66765039 68060470 2.2709 4.2344 NA NA NA NA WCM14-TP3 X 6838122299663472 −0.4952 −0.365 NA NA NA NA WCM14-TP3 X 99840019 1542756120.1065 1.2544 NA NA NA NA WCM14-TP3 X 154282994 154509348 −0.4333−0.1315 NA NA NA NA WCM14-TP4 1 762244 108309127 −0.1206 0.7541 2.22011.1531 2 1 WCM14-TP4 1 108311173 111217122 −0.6955 −0.1035 1.8091 0.05242 0 WCM14-TP4 1 111217233 193099346 −0.155 0.707 2.1533 1.1115 2 1WCM14-TP4 1 193104708 207245580 0.3538 1.3684 2.7799 2.3838 3 2WCM14-TP4 1 207252295 249212725 −0.1302 0.741 2.2538 1.0889 2 1WCM14-TP4 10 225938 49450424 0.1025 1.0505 2.1169 2.0256 2 2 WCM14-TP410 49452867 70531217 −0.2358 0.5947 1.9347 1.0855 2 1 WCM14-TP4 1070531237 70666793 0.2949 1.2952 NA NA NA NA WCM14-TP4 10 7067010481343103 0.6873 1.7709 4.238 2.5875 4 3 WCM14-TP4 10 81372081 135378940−0.5202 0.1767 2.1937 0.067 2 0 WCM14-TP4 11 193096 4562903 0.02570.9501 3.3775 0.4865 3 0 WCM14-TP4 11 4566572 7065231 −0.7894 −0.26261.7377 −0.0705 2 0 WCM14-TP4 11 7067923 11964668 −0.1523 0.7107 2.87840.3949 3 0 WCM14-TP4 11 11969414 21392487 −0.0147 0.8967 3.4183 0.3052 30 WCM14-TP4 11 21556002 48328606 −0.1167 0.7594 2.8756 0.51 3 1WCM14-TP4 11 48346648 134257766 0.0358 0.9633 2.7007 1.1989 3 1WCM14-TP4 12 247582 4830082 0.1686 1.1356 2.2111 2.183 2 2 WCM14-TP4 124835755 38712161 −0.2266 0.6075 2.1689 0.8784 2 1 WCM14-TP4 12 3871226551636326 0.1157 1.0675 2.1093 2.0823 2 2 WCM14-TP4 12 51639763 534429830.5455 1.6021 3.0468 3.0249 3 3 WCM14-TP4 12 53443938 92538269 −0.04420.8574 1.8214 1.802 2 2 WCM14-TP4 12 92539254 133778796 0.6526 1.72994.2288 2.4053 4 2 WCM14-TP4 12 133779108 133810735 −0.123 0.7509 NA NANA NA WCM14-TP4 13 19601153 45841502 −0.6222 0.0161 1.9532 0.0692 2 0WCM14-TP4 13 45857742 111102128 −1.1943 −1.0601 0.9232 0.036 1 0WCM14-TP4 13 111102728 115089411 −0.419 0.33 2.3453 0.1687 2 0 WCM14-TP414 19110188 107283269 0.2181 1.1985 2.4812 2.109 2 2 WCM14-TP4 1520087605 25287234 −0.4032 0.3533 1.6991 0.856 2 1 WCM14-TP4 15 2529671925515016 1.5225 2.7158 NA NA NA NA WCM14-TP4 15 25523597 102389685−0.5678 0.1025 1.1327 1.0146 1 1 WCM14-TP4 16 97503 34681533 0.17541.1442 2.2357 2.1849 2 2 WCM14-TP4 16 34681928 73127412 −0.4709 0.2521.2937 1.0881 1 1 WCM14-TP4 16 73161291 77246795 0.0271 0.9519 2.40061.4683 2 1 WCM14-TP4 16 77317756 80577227 −0.1932 0.6542 1.6088 1.5388 22 WCM14-TP4 16 80581631 81735431 −0.9684 −0.5891 1.2576 0.0719 1 0WCM14-TP4 16 81736324 90110950 −0.246 0.5803 1.6469 1.3434 2 1 WCM14-TP416 90124787 90168697 0.0102 0.9296 NA NA NA NA WCM14-TP4 17 1315955461799 0.2513 1.2405 2.3926 2.3331 2 2 WCM14-TP4 17 5461970 21207909−0.623 0.0149 1.9941 0.0267 2 0 WCM14-TP4 17 21208449 81052321 0.18341.1544 2.2373 2.2146 2 2 WCM14-TP4 18 47669 19444692 0.0295 0.95512.3775 1.4998 2 1 WCM14-TP4 18 19751215 78005164 −0.6036 0.046 2.0130.0518 2 0 WCM14-TP4 19 281404 7990208 −0.4153 0.3355 2.4054 0.1182 2 0WCM14-TP4 19 7992052 8977614 0.2701 1.2642 2.438 2.3657 2 2 WCM14-TP4 198979199 9033680 2.0385 3.2717 10.3457 8.9694 10  9 WCM14-TP4 19 903811611687888 0.0918 1.0365 2.0566 2.046 2 2 WCM14-TP4 19 11688178 125763711.2073 2.3672 NA NA NA NA WCM14-TP4 19 12577245 19824936 0.2112 1.18982.2929 2.2697 2 2 WCM14-TP4 19 19825314 30020678 1.5422 2.7372 7.3455.9908 7 6 WCM14-TP4 19 30021023 52794214 0.1402 1.0991 2.2386 2.0458 22 WCM14-TP4 19 52794435 54304573 1.3147 2.487 5.6184 5.5935 6 6WCM14-TP4 19 54307335 59083953 0.1056 1.0544 2.0957 2.0581 2 2 WCM14-TP42 41595 173913468 −0.1735 0.6815 1.9629 1.2447 2 1 WCM14-TP4 2 173916507186678794 −0.596 0.0581 1.056 1.0262 1 1 WCM14-TP4 2 186680222 242946607−0.1351 0.7343 1.8753 1.4518 2 1 WCM14-TP4 20 68413 377219 −0.8348−0.3423 NA NA NA NA WCM14-TP4 20 377341 25507117 0.1383 1.0966 2.16062.1165 2 2 WCM14-TP4 20 25596639 30454862 −0.0679 0.8255 2.7786 0.7656 31 WCM14-TP4 20 30457341 40710558 −0.4567 0.2735 1.3071 1.1104 1 1WCM14-TP4 20 40713478 62905001 −0.0802 0.809 2.2084 1.2956 2 1 WCM14-TP421 9907274 14414885 0.214 1.1934 NA NA NA NA WCM14-TP4 21 1441856717163811 −0.9039 −0.4675 1.4834 −0.037 1 0 WCM14-TP4 21 1717213348084211 0.2387 1.2246 2.3487 2.3251 2 2 WCM14-TP4 22 17052984 51219090−0.2283 0.6052 2.9424 0.0999 3 0 WCM14-TP4 3 239390 7678056 0.35731.3727 3.1853 1.9939 3 2 WCM14-TP4 3 7721887 16216718 −0.4916 0.22062.2498 0.0805 2 0 WCM14-TP4 3 16217091 33093505 0.3765 1.3965 2.76572.4995 3 2 WCM14-TP4 3 33095121 37369237 −0.3615 0.4146 1.835 0.8309 2 1WCM14-TP4 3 37370061 45588862 0.2972 1.2981 2.4806 2.4376 2 2 WCM14-TP43 45636355 49701148 −0.7299 −0.1609 1.832 −0.0431 2 0 WCM14-TP4 349701298 52864584 −0.3796 0.3882 1.8853 0.7323 2 1 WCM14-TP4 3 5286728853925849 −0.7462 −0.1884 1.8225 −0.0674 2 0 WCM14-TP4 3 5415766261975367 0.6618 1.7408 3.366 3.3185 3 3 WCM14-TP4 3 61989192 85985017−0.1333 0.7368 3.2917 0.0413 3 0 WCM14-TP4 3 86010600 113392192 0.07221.0111 2.0364 1.9944 2 2 WCM14-TP4 3 113393747 125691052 −0.6212 0.0178NA NA NA NA WCM14-TP4 3 125694554 182631792 0.247 1.235 2.3806 2.3272 22 WCM14-TP4 3 182631843 184070076 −0.2454 0.5812 1.9242 1.0679 2 1WCM14-TP4 3 184070332 197847390 0.2142 1.1936 2.3017 2.2727 2 2WCM14-TP4 4 53446 55156400 −0.2117 0.6285 1.8957 1.1962 2 1 WCM14-TP4 455156739 72634975 0.4015 1.4273 2.7026 2.6762 3 3 WCM14-TP4 4 7264981974088854 −0.342 0.443 NA NA NA NA WCM14-TP4 4 74124154 85648113 0.08951.0336 2.5978 1.4965 3 1 WCM14-TP4 4 85654548 142642271 −0.3368 0.45061.6893 1.0439 2 1 WCM14-TP4 4 142643062 187179210  1.00E−04 0.91631.8998 1.8748 2 2 WCM14-TP4 4 187188406 190862042 −0.5393 0.1472 NA NANA NA WCM14-TP4 5 140712 44388822 0.3669 1.3847 2.6208 2.6014 3 3WCM14-TP4 5 44809079 139893044 −0.2335 0.5979 2.9297 0.0973 3 0WCM14-TP4 5 139903824 141359805 −0.7203 −0.1448 2.0213 −0.2123 2 0WCM14-TP4 5 141362974 180687847 −0.1889 0.6602 3.0673 0.0933 3 0WCM14-TP4 6 203479 62687896 −0.2077 0.634 1.9588 1.1449 2 1 WCM14-TP4 662757908 66803535 −1.4967 −1.873 NA NA NA NA WCM14-TP4 6 66803647110036274 −0.2439 0.5832 1.8613 1.1351 2 1 WCM14-TP4 6 110037614133767925 −0.0042 0.9107 2.6701 1.0897 3 1 WCM14-TP4 6 133769200149285623 −0.2891 0.5192 1.7892 1.0772 2 1 WCM14-TP4 6 149340390152688397 −1.1754 −1.0175 0.9755 0.0125 1 0 WCM14-TP4 6 152690092158850920 −0.1461 0.7192 2.132 1.1606 2 1 WCM14-TP4 6 158870063159672491 −0.9283 −0.5129 1.4194 −0.0178 1 0 WCM14-TP4 6 159677528160209172 −0.1396 0.7282 NA NA NA NA WCM14-TP4 6 160210407 1665792700.2073 1.1848 2.7698 1.7769 3 2 WCM14-TP4 6 166580193 170892825 −0.60230.0481 1.9627 0.1051 2 0 WCM14-TP4 7 193346 822145 0.2021 1.1783 NA NANA NA WCM14-TP4 7 822522 38254631 −0.09 0.7957 2.1635 1.3085 2 1WCM14-TP4 7 38256597 38768322 0.3331 1.3428 NA NA NA NA WCM14-TP4 738780883 40132331 1.4162 2.5991 10.0223 2.0959 10  2 WCM14-TP4 740132599 56155396 0.2135 1.1927 2.3496 2.222 2 2 WCM14-TP4 7 5615551965447001 1.4584 2.6455 6.4632 6.051 6 6 WCM14-TP4 7 65541029 1589373610.3511 1.3651 2.8853 2.2667 3 2 WCM14-TP4 8 190879 43054665 −0.56560.1061 2.1067 0.0459 2 0 WCM14-TP4 8 43147666 144650419 1.0349 2.1736.5686 2.4503 7 2 WCM14-TP4 8 144651838 146279349 0.5238 1.576 4.6781.2849 5 1 WCM14-TP4 9 214656 17579306 −1.0884 −0.8293 1.0707 0.0549 1 0WCM14-TP4 9 17747173 21968164 0.6846 1.7678 6.6037 0.2068 7 0 WCM14-TP49 21968695 32541876 −0.2355 0.5952 3.0969 −0.0756 3 0 WCM14-TP4 932542204 71225850 −0.0453 0.8559 1.965 1.6548 2 2 WCM14-TP4 9 71395044141016459 −0.0808 0.8081 3.3653 0.1364 3 0 WCM14-TP4 X 2700084 652388500.7669 1.8643 NA NA NA NA WCM14-TP4 X 65241997 68060461 2.2546 3.5005 NANA NA NA WCM14-TP4 X 68381282 96140065 −0.7377 −0.1741 NA NA NA NAWCM14-TP4 X 96167496 153735196 0.17 1.1374 NA NA NA NA WCM14-TP4 X153760604 153940861 −0.5194 0.1779 NA NA NA NA WCM14-TP4 X 153941673154509348 0.3368 1.3473 NA NA NA NA WCM14_x1_1 1 762178 145096653−0.1975 0.6499 2.0503 1.0877 2 1 WCM14_x1_1 1 145103928 249212761 0.02161.0443 2.0798 2.0448 2 2 WCM14_x1_1 10 225995 38120558 0.01 1.02452.0516 2.0168 2 2 WCM14_x1_1 10 38121054 70229735 0.1307 1.2249 2.37522.2997 2 2 WCM14_x1_1 10 70229941 70502336 0.0408 1.0767 NA NA NA NAWCM14_x1_1 10 70507061 77818559 0.4741 1.7451 4.1572 2.5473 4 3WCM14_x1_1 10 78084125 81317809 0.9943 2.4416 NA NA NA NA WCM14_x1_1 1081318621 112582191 −0.3426 0.3574 2.6494 −0.0871 3 0 WCM14_x1_1 10112583342 135379059 −0.4792 0.0503 2.0575 0.0135 2 0 WCM14_x1_1 11193096 15994502 0.0049 1.0159 2.0429 2.0013 2 2 WCM14_x1_1 11 1600788951527499 −0.2243 0.598 1.9978 1.0294 2 1 WCM14_x1_1 11 55110668134257807 0.1947 1.3268 2.9783 2.0388 3 2 WCM14_x1_1 12 247582 39069551−0.1978 0.6493 2.0796 1.0571 2 1 WCM14_x1_1 12 39071220 89919715 0.2361.3914 3.0254 2.2211 3 2 WCM14_x1_1 12 89984716 133810874 0.0109 1.0262.0572 2.0155 2 2 WCM14_x1_1 13 19601049 115089411 −0.4766 0.0564 2.07110.0087 2 0 WCM14_x1_1 14 19110203 107283263 0.0183 1.0387 2.0648 2.04382 2 WCM14_x1_1 15 20087605 22440726 −0.1645 0.7125 2.7681 0.5091 3 1WCM14_x1_1 15 22448436 37387827 −0.1878 0.6685 1.9407 1.2381 2 1WCM14_x1_1 15 37388647 102389672 0.0074 1.02 2.0453 2.0106 2 2WCM14_x1_1 16 97424 34682250 0.0514 1.0945 2.1568 2.1139 2 2 WCM14_x1_116 46508189 72993860 −0.1477 0.7438 2.1914 1.1577 2 1 WCM14_x1_1 1672993919 76461500 0.0707 1.1267 2.2923 2.075 2 2 WCM14_x1_1 16 7648194080583456 −0.1745 0.6936 1.8863 1.3484 2 1 WCM14_x1_1 16 8058434282660739 −0.7766 −0.7996 1.09 0.059 1 0 WCM14_x1_1 16 82892037 90168701−0.1544 0.7313 2.0383 1.2821 2 1 WCM14_x1_1 17 131595 5463332 0.00711.0195 2.0619 1.9925 2 2 WCM14_x1_1 17 5485295 21188211 −0.4859 0.0342.0411 0.0067 2 0 WCM14_x1_1 17 21201719 81052366 0.026 1.0518 2.09412.052 2 2 WCM14_x1_1 18 47665 19444692 −0.0431 0.9327 1.949 1.8687 2 2WCM14_x1_1 18 19751194 78005243 −0.4954 0.0113 2.0356 −0.0198 2 0WCM14_x1_1 19 281445 7853194 −0.4755 0.059 2.1457 −0.0622 2 0 WCM14_x1_119 7911577 59083968 0.0227 1.0461 2.0649 2.0649 2 2 WCM14_x1_1 2 41595242946597 −0.0189 0.9748 1.9857 1.9449 2 2 WCM14_x1_1 20 68375 361498310.0364 1.0694 2.1233 2.0738 2 2 WCM14_x1_1 20 36150779 37662857 −0.20520.635 2.0706 1.0354 2 1 WCM14_x1_1 20 37667223 45140783 0.0375 1.07112.2391 1.963 2 2 WCM14_x1_1 20 45169921 62905001 −0.1826 0.6783 2.09861.1018 2 1 WCM14_x1_1 21 9826166 17116365 −0.4937 0.0154 2.0126 0.0088 20 WCM14_x1_1 21 17135323 48084196 0.0054 1.0166 2.0474 1.9989 2 2WCM14_x1_1 22 16255826 51219089 −0.045 0.9293 1.9277 1.8809 2 2WCM14_x1_1 3 239405 7678010 0.3716 1.5963 3.8047 2.2428 4 2 WCM14_x1_1 37721765 15915357 −0.3659 0.3074 2.5731 −0.0981 3 0 WCM14_x1_1 3 1621673333058287 0.3997 1.6375 3.6164 2.6063 4 3 WCM14_x1_1 3 33059967 33728618−0.398 0.2371 NA NA NA NA WCM14_x1_1 3 33729756 41953086 0.0579 1.10542.2664 2.0366 2 2 WCM14_x1_1 3 41954265 45636356 0.4276 1.6782 3.77082.6296 4 3 WCM14_x1_1 3 45636831 49751551 −0.3836 0.269 2.4185 −0.0086 20 WCM14_x1_1 3 49753144 52726769 0.1455 1.2486 NA NA NA NA WCM14_x1_1 352726992 54157609 −0.4861 0.0336 2.0135 0.0336 2 0 WCM14_x1_1 3 5435443159997092 0.4851 1.7608 3.4901 3.2874 3 3 WCM14_x1_1 3 59999866 90274787−0.1953 0.654 3.1701 −0.0231 3 0 WCM14_x1_1 3 90306533 113464797 0.2741.4498 2.9695 2.494 3 2 WCM14_x1_1 3 113497697 125400268 −0.3866 0.2625NA NA NA NA WCM14_x1_1 3 125690929 128363758 0.4147 1.6595 3.8764 2.44184 2 WCM14_x1_1 3 128369437 142840524 0.246 1.4068 2.7047 2.5984 3 3WCM14_x1_1 3 142840735 147106695 0.3455 1.5577 3.9036 1.9839 4 2WCM14_x1_1 3 147108697 170244659 0.4131 1.6571 3.9393 2.3685 4 2WCM14_x1_1 3 170425809 180359790 0.2472 1.4087 2.7532 2.5567 3 3WCM14_x1_1 3 180361950 184035229 0.1193 1.2064 2.36 2.2551 2 2WCM14_x1_1 3 184035306 197847416 0.3028 1.4936 3.1605 2.4712 3 2WCM14_x1_1 4 53446 48896047 −0.2018 0.6415 2.0518 1.0681 2 1 WCM14_x1_14 48899857 83424202 0.0193 1.0404 2.0848 2.0289 2 2 WCM14_x1_1 483425726 151770138 −0.107 0.8186 2.0551 1.4722 2 1 WCM14_x1_1 4151770561 190862042 0.0233 1.0471 2.1049 2.0278 2 2 WCM14_x1_1 5 14068545696169 0.02 1.0415 2.0898 2.0269 2 2 WCM14_x1_1 5 49695023 68800075−0.8654 −1.1383 0.8954 0.0131 1 0 WCM14_x1_1 5 68804987 180687854−0.1966 0.6516 3.136 0.0057 3 0 WCM14_x1_1 6 203374 397277 −0.07760.8716 NA NA NA NA WCM14_x1_1 6 398888 57512718 −0.1263 0.7835 2.3281.1145 2 1 WCM14_x1_1 6 62284247 69653778 −0.4508 0.1172 2.1572 0.0121 20 WCM14_x1_1 6 69665899 85473891 −0.0573 0.9077 1.9125 1.8395 2 2WCM14_x1_1 6 86160065 89675638 0.2896 1.4735 NA NA NA NA WCM14_x1_1 689790810 90097350 −0.5673 −0.17 NA NA NA NA WCM14_x1_1 6 90121630110620349 0.1222 1.2111 2.7619 1.8684 3 2 WCM14_x1_1 6 110636524135263579 0.3 1.4894 3.7759 1.8394 4 2 WCM14_x1_1 6 135264946 1490687900.1199 1.2073 2.8376 1.7806 3 2 WCM14_x1_1 6 149208148 152673420 −0.6044−0.2692 1.701 −0.0414 2 0 WCM14_x1_1 6 152674455 158735342 0.106 1.18482.96 1.5865 3 2 WCM14_x1_1 6 158834198 159692405 −0.5538 −0.1348 1.65570.1659 2 0 WCM14_x1_1 6 160103568 166581100 0.1501 1.2561 3.1348 1.64213 2 WCM14_x1_1 6 166720806 170892860 −0.6062 −0.2742 1.6358 0.018 2 0WCM14_x1_1 7 193355 56126419 0.0041 1.0144 2.0477 1.9923 2 2 WCM14_x1_17 56128090 158937357 0.4163 1.6618 4.1585 2.1699 4 2 WCM14_x1_1 8 19089748068823 −0.4816 0.0444 2.0564 0.0061 2 0 WCM14_x1_1 8 48114127146279324 0.9367 2.3683 8.2334 2.0932 8 2 WCM14_x1_1 9 214650 17747173−0.8 −0.8833 1.1286 −0.0443 1 0 WCM14_x1_1 9 17761444 20821092 0.25861.4262 5.3529 0.0217 5 0 WCM14_x1_1 9 20823142 32635545 −0.2703 0.50682.8194 0.0224 3 0 WCM14_x1_1 9 32784246 34297030 0.6745 2.0237 4.28113.8516 4 4 WCM14_x1_1 9 34306436 66513346 0.393 1.6277 3.9463 2.2342 4 2WCM14_x1_1 9 66514076 141016459 −0.4559 0.1052 2.1821 −0.0308 2 0WCM14_x1_1 X 2700146 17092203 0.2093 1.3498 NA NA NA NA WCM14_x1_1 X17095487 65835787 0.2717 1.4464 NA NA NA NA WCM14_x1_1 X 6676503367751827 1.1607 2.649 NA NA NA NA WCM14_x1_1 X 67867798 82764141 0.28881.4723 NA NA NA NA WCM14_x1_1 X 82764391 154509348 0.1566 1.2665 NA NANA NA WCM14_Z11_1 1 721476 89448868 −0.1336 0.6086 2.0072 1.0423 2 1WCM14_Z11_1 1 89449069 91406840 0.2076 1.0328 NA NA NA NA WCM14_Z11_1 191447883 92711097 −0.1735 0.5572 NA NA NA NA WCM14_Z11_1 1 92712203102270469 −0.4289 0.2181 1.359 0.9674 1 1 WCM14_Z11_1 1 102271671104080004 −0.1871 0.5397 NA NA NA NA WCM14_Z11_1 1 104084022 111738612−0.7935 −0.308 1.5298 0.0857 2 0 WCM14_Z11_1 1 111739874 119965099−0.3623 0.3085 1.3668 1.1101 1 1 WCM14_Z11_1 1 119985626 1971502250.0649 0.8583 2.5795 1.0463 3 1 WCM14_Z11_1 1 197157513 207200888 0.34931.2024 2.364 2.2384 2 2 WCM14_Z11_1 1 207222535 249212424 −0.1723 0.55882.6236 0.3226 3 0 WCM14_Z11_1 10 225980 70482258 −0.1827 0.5454 1.93520.9837 2 1 WCM14_Z11_1 10 70496707 77818522 0.5741 1.4655 3.6962 1.82684 2 WCM14_Z11_1 10 78084229 81371653 1.0815 2.0378 NA NA NA NAWCM14_Z11_1 10 81372081 135381800 −0.5264 0.0829 2.0708 0.0475 2 0WCM14_Z11_1 11 193151 48328093 0.0239 0.8074 2.7849 0.7152 3 1WCM14_Z11_1 11 48328327 56510600 0.0651 0.8586 1.8715 1.7549 2 2WCM14_Z11_1 11 56756798 134856562 0.0864 0.8848 2.8931 0.8 3 1WCM14_Z11_1 12 148674 4737849 0.0673 0.8612 1.9086 1.7245 2 2WCM14_Z11_1 12 4758290 39161492 −0.1786 0.5506 2.0516 0.8778 2 1WCM14_Z11_1 12 39242372 47471439 0.033 0.8187 1.8427 1.6849 2 2WCM14_Z11_1 12 47471567 64609742 0.1633 0.979 1.9782 1.9638 2 2WCM14_Z11_1 12 64616006 91347928 0.0838 0.8817 1.9424 1.7426 2 2WCM14_Z11_1 12 91348155 133810880 0.5575 1.4463 3.567 1.883 4 2WCM14_Z11_1 13 19601063 45841502 −0.5714 0.0193 2.0244 0.0026 2 0WCM14_Z11_1 13 45857620 111896592 −1.0766 −0.7675 1.1198 0.055 1 0WCM14_Z11_1 13 111917932 115089411 −0.5388 0.0655 2.1099 −0.017 2 0WCM14_Z11_1 14 19377698 27064664 0.2143 1.0409 2.0848 2.0301 2 2WCM14_Z11_1 14 27065792 65008406 0.0936 0.8936 2.1162 1.5995 2 2WCM14_Z11_1 14 65008685 107283074 0.2087 1.034 2.07 2.0254 2 2WCM14_Z11_1 15 20170150 22466489 −0.6466 −0.0888 1.3715 0.5091 1 1WCM14_Z11_1 15 22482966 38234397 −0.8998 −0.4742 1.0759 0.3639 1 0WCM14_Z11_1 15 38235545 102515352 −0.4606 0.1745 1.2905 0.9666 1 1WCM14_Z11_1 16 65607 33961499 0.1412 0.9521 1.9347 1.9347 2 2WCM14_Z11_1 16 33961702 80584447 −0.145 0.594 1.9804 1.0385 2 1WCM14_Z11_1 16 80638372 82197800 −1.0043 −0.6445 1.1931 0.0863 1 0WCM14_Z11_1 16 82660694 90233294 −0.1743 0.5563 1.9376 1.0033 2 1WCM14_Z11_1 17 131595 5463107 0.1278 0.9357 1.9175 1.9081 2 2WCM14_Z11_1 17 5463309 21191346 −0.5124 0.1026 2.0923 0.0552 2 0WCM14_Z11_1 17 21194843 81083525 0.1413 0.9522 1.9442 1.9253 2 2WCM14_Z11_1 18 48259 19438557 −0.1641 0.5694 1.9831 0.9848 2 1WCM14_Z11_1 18 19751342 78005201 −0.5267 0.0825 2.0674 0.0504 2 0WCM14_Z11_1 19 281439 7833861 −0.5221 0.089 2.0663 0.0609 2 0WCM14_Z11_1 19 7911442 32083584 0.1779 0.9967 2.0173 1.9736 2 2WCM14_Z11_1 19 32083892 59083988 −0.029 0.7412 2.0013 1.3419 2 1WCM14_Z11_1 2 41614 92129784 −0.1973 0.5265 1.8198 1.061 2 1 WCM14_Z11_12 95537342 131099795 −0.0038 0.7728 1.7364 1.6808 2 2 WCM14_Z11_1 2131100690 242946589 −0.198 0.5255 1.7327 1.1462 2 1 WCM14_Z11_1 20 6836321695381 −0.0441 0.7223 1.9553 1.3443 2 1 WCM14_Z11_1 20 2256267425755672 0.223 1.0513 2.21 1.9349 2 2 WCM14_Z11_1 20 26063602 30437652−0.0499 0.715 NA NA NA NA WCM14_Z11_1 20 30438475 41101195 −0.27390.4263 1.6521 1.0354 2 1 WCM14_Z11_1 20 41306600 62904848 0.025 0.80881.8106 1.6929 2 2 WCM14_Z11_1 21 9907304 16423152 −0.6782 −0.1351 NA NANA NA WCM14_Z11_1 21 17102741 48084207 0.1069 0.9101 1.9022 1.8561 2 2WCM14_Z11_1 22 16449708 51219138 −0.5106 0.1051 2.1089 0.0422 2 0WCM14_Z11_1 3 239436 7649779 0.2928 1.1352 2.7557 1.6374 3 2 WCM14_Z11_13 7721939 15915340 −0.502 0.1171 2.109 0.0602 2 0 WCM14_Z11_1 3 1621673132995599 0.3004 1.1443 2.6299 1.7908 3 2 WCM14_Z11_1 3 32995928 419253820.04 0.8274 1.8053 1.7436 2 2 WCM14_Z11_1 3 41938332 45636376 0.37281.2302 2.5458 2.1463 3 2 WCM14_Z11_1 3 45636700 49298139 −0.4941 0.12812.1153 0.0705 2 0 WCM14_Z11_1 3 49298484 49751596 −1.0114 −0.6565 1.25410.0147 1 0 WCM14_Z11_1 3 49753099 52658955 −0.0969 0.6555 NA NA NA NAWCM14_Z11_1 3 52661350 53836179 −0.9303 −0.5231 NA NA NA NA WCM14_Z11_13 53837510 54157561 −0.1619 0.5722 NA NA NA NA WCM14_Z11_1 3 5435455259999828 0.4812 1.3576 2.5626 2.5626 3 3 WCM14_Z11_1 3 60522689 85984919−0.152 0.585 3.0237 −0.0236 3 0 WCM14_Z11_1 3 86010623 113441818 0.04420.8326 1.8317 1.7301 2 2 WCM14_Z11_1 3 113442385 125313565 −0.4971 0.124NA NA NA NA WCM14_Z11_1 3 125649401 128526493 0.4175 1.283 2.9372 1.92983 2 WCM14_Z11_1 3 128532190 142775178 0.1357 0.9453 1.9727 1.8785 2 2WCM14_Z11_1 3 142839762 180359919 0.2553 1.0902 2.3848 1.8733 2 2WCM14_Z11_1 3 180361955 184042761 −0.148 0.5901 2.0275 0.9832 2 1WCM14_Z11_1 3 184043303 197894712 0.1402 0.9508 2.0345 1.8314 2 2WCM14_Z11_1 4 59327 57899380 −0.1667 0.566 1.9386 1.0223 2 1 WCM14_Z11_14 57907036 83838806 0.2686 1.1062 2.824 1.4816 3 1 WCM14_Z11_1 483839054 84028971 0.0731 0.8684 NA NA NA NA WCM14_Z11_1 4 84185374151773593 −0.1714 0.5599 1.9366 1.0118 2 1 WCM14_Z11_1 4 151773951190426570 0.0728 0.868 1.868 1.7824 2 2 WCM14_Z11_1 5 140682 496991170.2255 1.0544 2.1244 2.0292 2 2 WCM14_Z11_1 5 49706728 180687769 −0.1660.5669 2.9462 0.0164 3 0 WCM14_Z11_1 6 203561 62407127 −0.1453 0.59351.972 1.0459 2 1 WCM14_Z11_1 6 62442604 69349121 −1.1824 −0.9556 NA NANA NA WCM14_Z11_1 6 69640532 110636619 −0.2034 0.5185 1.9237 0.9411 2 1WCM14_Z11_1 6 110643995 135239816 0.0896 0.8887 2.8137 0.8893 3 1WCM14_Z11_1 6 135250239 149068711 −0.1669 0.5658 1.967 0.9935 2 1WCM14_Z11_1 6 149208150 152673418 −1.0773 −0.7687 1.0998 0.0741 1 0WCM14_Z11_1 6 152674455 158834221 −0.0906 0.6634 2.0165 1.1512 2 1WCM14_Z11_1 6 158850844 159688951 −1.1042 −0.8155 1.0486 0.0878 1 0WCM14_Z11_1 6 160103542 166580882 −0.0872 0.6678 1.873 1.3042 2 1WCM14_Z11_1 6 166720806 170893661 −0.5573 0.0394 2.0223 0.0331 2 0WCM14_Z11_1 7 193265 38785175 −0.157 0.5785 1.9699 1.0167 2 1WCM14_Z11_1 7 38791817 40174670 1.2752 2.2503 NA NA NA NA WCM14_Z11_1 740220595 56130404 0.1108 0.9149 1.9317 1.8391 2 2 WCM14_Z11_1 7 56130723158937268 0.3548 1.209 2.8571 1.7664 3 2 WCM14_Z11_1 8 190906 43212022−0.5221 0.0889 2.0783 0.0489 2 0 WCM14_Z11_1 8 47752745 146279480 0.89411.8294 5.346 1.7618 5 2 WCM14_Z11_1 9 17040 17579284 −1.06 −0.73881.1573 0.0411 1 0 WCM14_Z11_1 9 17747099 20823070 1.0279 1.9785 NA NA NANA WCM14_Z11_1 9 20862634 32567188 −0.1173 0.6294 NA NA NA NAWCM14_Z11_1 9 32567414 32635509 0.1886 1.0098 NA NA NA NA WCM14_Z11_1 932784303 34256832 0.5149 1.3969 3.6192 1.6474 4 2 WCM14_Z11_1 9 3425709571395287 0.1588 0.9736 2.3847 1.5427 2 2 WCM14_Z11_1 9 71395435141111414 −0.1508 0.5865 2.9454 0.0578 3 0 WCM14_Z11_1 X 270014865392239 0.7989 1.7222 NA NA NA NA WCM14_Z11_1 X 65393522 680604761.7319 2.7419 NA NA NA NA WCM14_Z11_1 X 68381398 92964855 −0.5647 0.0289NA NA NA NA WCM14_Z11_1 X 95940147 154509348 −0.0441 0.7222 NA NA NA NAWCM15 1 14907 10428452 0.05 0.7375 1.6673 1.6673 2 2 WCM15 1 1043115812780953 −0.1663 −0.9906 0.9638 0.0427 1 0 WCM15 1 12785247 2492139640.0283 0.625 1.5422 1.5422 2 2 WCM15 10 226093 88649941 −0.0013 0.45931.3749 1.3749 1 1 WCM15 10 88650021 95326754 −0.315 NA −0.1039 −0.2987 00 WCM15 10 95335903 135477891 0.0328 0.6489 1.568 1.568 2 2 WCM15 11180151 134605849 0.0068 0.5062 1.4203 1.4203 1 1 WCM15 12 14846513768448 −0.1521 −0.7994 0.7708 0.3784 1 0 WCM15 12 13769404 1334488250.0402 0.6877 1.6107 1.6107 2 2 WCM15 12 133454126 133810842 −0.1835−1.2576 NA NA NA NA WCM15 13 19042004 21753162 −0.1376 −0.6265 1.02940.2661 1 0 WCM15 13 21875699 48830390 0.203 1.3799 5.6698 −0.4648 6 0WCM15 13 48832327 115089411 −0.1923 −1.4161 0.5231 0.2263 1 0 WCM15 1419110194 107283210 0.2422 1.5153 2.8587 2.8587 3 3 WCM15 15 2008385759519598 −0.0869 −0.1351 0.9106 0.9106 1 1 WCM15 15 59523887 1014457570.0212 0.5868 1.5265 1.4774 2 1 WCM15 15 101447450 102514189 −0.1104−0.3442 1.3338 0.2417 1 0 WCM15 16 66888 90168693 −0.1869 −1.3171 0.6780.1247 1 0 WCM15 17 131595 16089921 0.0048 0.495 3.2727 −0.4541 3 0WCM15 17 16090076 21201579 −0.2245 −2.1914 0.6682 −0.2303 1 0 WCM15 1721201851 81187883 0.0461 0.7176 1.6445 1.6445 2 2 WCM15 18 4780678005197 −0.0721 −0.0165 2.3789 −0.4016 2 0 WCM15 19 105010 114119250.065 0.8112 1.7547 1.7547 2 2 WCM15 19 11417438 14655988 −0.2488−3.2717 0.2599 −0.0528 0 0 WCM15 19 14673353 59093696 0.1913 1.33762.5272 2.5272 3 3 WCM15 2 41614 243037022 −0.0701 −0.001 0.9993 0.9993 11 WCM15 20 68375 25657632 −0.1116 −0.3562 1.9545 −0.3921 2 0 WCM15 2025666249 62934623 0.1408 1.1444 2.2105 2.2105 2 2 WCM15 21 959031148084181 0.0366 0.6691 1.5901 1.5901 2 2 WCM15 22 16159014 51219089−0.17 −1.0447 0.6498 0.3197 1 0 WCM15 3 239436 197896662 0.0601 0.78731.7258 1.7258 2 2 WCM15 4 53346 77228138 −0.1405 −0.66 0.6329 0.6329 1 1WCM15 4 77230296 85416804 −0.3233 NA −0.2387 −0.2387 0 0 WCM15 485417019 190878508 −0.0857 −0.1257 0.9166 0.9166 1 1 WCM15 5 9075050125712 0.2346 1.4895 2.808 2.808 3 3 WCM15 5 50128684 148016583−0.0814 −0.0905 2.4426 −0.5642 2 −1  WCM15 5 148206440 180687808 0.25261.5497 2.9276 2.9276 3 3 WCM15 6 203428 19838753 0.0217 0.5898 1.5051.505 2 2 WCM15 6 19839429 28334474 −0.2377 −2.6809 0.2998 0.0121 0 0WCM15 6 28336407 170892860 0.0449 0.7116 1.6377 1.6377 2 2 WCM15 7193254 16823442 −0.1831 −1.2518 0.6191 0.2208 1 0 WCM15 7 16823775130294942 −0.002 0.4556 1.3714 1.3714 1 1 WCM15 7 130295322 132973648−0.021 0.3403 1.274 1.2581 1 1 WCM15 7 132973904 158738404 0.1651 1.23972.5335 2.1894 3 2 WCM15 7 158738484 158937158 −0.098 −0.2305 NA NA NA NAWCM15 8 163457 32152225 −0.1867 −1.3134 0.5514 0.2534 1 0 WCM15 832406215 145933686 0.0347 0.6589 1.5789 1.5789 2 2 WCM15 8 145946992146279510 −0.201 −1.5891 NA NA NA NA WCM15 9 14856 39178192 −0.06140.0651 1.0462 1.0462 1 1 WCM15 9 39817370 77752528 −0.3065 NA 0.0982−0.4242 0 0 WCM15 9 77755768 141107513 −0.0198 0.3476 1.2724 1.2724 1 1WCM15 X 2700162 26213604 0.3771 1.9241 NA NA NA NA WCM15 X 26235651154509348 0.0595 0.7846 NA NA NA NA WCM154 1 14907 16817677 −0.29640.1971 2.1785 0.1143 2 0 WCM154 1 16828222 17198659 −0.4363 −0.14921.555 0.2485 2 0 WCM154 1 17248500 28010508 −0.3374 0.1007 2.1192 0.02542 0 WCM154 1 28014988 51253917 0.3427 1.3903 2.6214 2.6214 3 3 WCM154 151267373 55452078 0.0126 0.8308 1.9294 1.6278 2 2 WCM154 1 5545748972739681 0.3286 1.3682 2.5855 2.5773 3 3 WCM154 1 72748016 107682908−0.0922 0.6312 3.0427 0.0549 3 0 WCM154 1 107683065 225339733 0.33081.3717 2.5918 2.5836 3 3 WCM154 1 225340546 226259090 −0.1489 0.5173 NANA NA NA WCM154 1 226332498 249213973 0.2986 1.3203 2.4973 2.4973 2 2WCM154 10 225989 135477891 −0.3536 0.0616 2.0356 0.0516 2 0 WCM154 11193112 134605959 −0.195 0.4213 1.3391 1.3391 1 1 WCM154 12 14844429519813 −0.3431 0.0869 2.1074 0.0167 2 0 WCM154 12 29521193 1209360810.0938 0.977 1.9684 1.9684 2 2 WCM154 12 120941464 132212822 0.36911.4316 2.7563 2.6388 3 3 WCM154 12 132237750 133810883 0.2137 1.1822.367 2.171 2 2 WCM154 13 19041979 36424881 0.3728 1.4374 3.9119 1.50474 2 WCM154 13 36428595 55015114 0.0688 0.9326 3.8789 −0.0615 4 0 WCM15413 55015454 115089411 0.3268 1.3653 3.7339 1.4186 4 1 WCM154 14 19110183107283263 0.136 1.0506 2.0714 2.0714 2 2 WCM154 15 20083885 23811262−0.2152 0.3782 1.9801 0.6194 2 1 WCM154 15 23811592 102506273 −0.13520.5452 2.8176 0.101 3 0 WCM154 16 67604 2581992 −0.2473 0.308 2.36050.1154 2 0 WCM154 16 2593705 33965560 0.1931 1.1475 2.2153 2.2153 2 2WCM154 16 34274675 90168697 −0.3378 0.0998 2.1183 0.025 2 0 WCM154 17131595 440373 0.126 1.0332 NA NA NA NA WCM154 17 455146 17210003 −0.33650.1029 2.137 0.0109 2 0 WCM154 17 17226544 80038011 −0.0515 0.71032.0187 1.2535 2 1 WCM154 17 80038478 81052563 0.189 1.1408 2.205 2.205 22 WCM154 18 47800 78005123 0.1581 1.0884 2.1263 2.1263 2 2 WCM154 19104935 59093696 0.1303 1.0406 2.0571 2.0571 2 2 WCM154 2 41662 69300093−0.062 0.6901 1.8874 1.3394 2 1 WCM154 2 69302835 243037022 −0.346 0.082.0542 0.0598 2 0 WCM154 20 68351 62934623 −0.0511 0.7109 1.6368 1.63682 2 WCM154 21 9590331 34030022 −0.3656 0.032 1.8851 0.1598 2 0 WCM154 2134037433 42839671 0.2375 1.2213 2.3815 2.2818 2 2 WCM154 21 4283987848084211 −0.3224 0.1365 2.1623 0.0361 2 0 WCM154 22 16159043 51223730−0.3021 0.1839 1.7712 0.5007 2 1 WCM154 3 239431 90279242 0.0676 0.93061.906 1.906 2 2 WCM154 3 90283452 107097091 −0.3843 −0.0146 1.97840.0014 2 0 WCM154 3 107097387 185641782 0.3326 1.3745 2.6501 2.5355 3 3WCM154 3 185643220 197896740 0.113 1.0107 2.0148 2.0148 2 2 WCM154 453435 184828290 −0.3747 0.0096 1.0067 1.0067 1 1 WCM154 4 184910040190874234 −0.763 −1.2684 0.9092 −0.079 1 0 WCM154 5 90537 340432270.3678 1.4296 2.7608 2.6266 3 3 WCM154 5 34175975 34193028 −0.7179−1.0711 NA NA NA NA WCM154 5 34526264 64981293 0.3506 1.4027 2.75172.5362 3 3 WCM154 5 65000283 74018300 −0.3909 −0.0312 1.9799 −0.0228 2 0WCM154 5 74021755 82406889 0.38 1.4485 2.7969 2.6616 3 3 WCM154 582491751 90136848 −0.4045 −0.066 1.8294 0.0812 2 0 WCM154 5 90144522180687814 0.3506 1.4028 2.6855 2.6026 3 3 WCM154 6 203364 786330790.0839 0.9596 1.9447 1.9447 2 2 WCM154 6 79424459 102516718 −0.3867−0.0205 1.9977 −0.0259 2 0 WCM154 6 105176968 170892855 0.1002 0.98821.9837 1.9837 2 2 WCM154 7 193222 158937066 0.0845 0.9605 1.9459 1.94592 2 WCM154 8 163532 146279533 0.1479 1.0709 2.1007 2.1007 2 2 WCM154 914878 79007527 0.0868 0.9647 1.9516 1.9516 2 2 WCM154 9 7900907786905107 −0.3596 0.0467 1.9372 0.1287 2 0 WCM154 9 86907582 936578700.1431 1.0627 2.0888 2.0888 2 2 WCM154 9 93976491 95571939 −0.33090.1162 2.2337 −0.0659 2 0 WCM154 9 95575820 95609878 0.2736 1.2802 NA NANA NA WCM154 9 95610230 130104684 0.1447 1.0654 2.0928 2.0928 2 2 WCM1549 130106435 141107513 0.2657 1.2673 2.4072 2.4072 2 2 WCM154 X 27001599656265 0.1244 1.0305 NA NA NA NA WCM154 X 9659738 38547899 0.08210.9563 NA NA NA NA WCM154 X 38664196 39935801 −1.1843 NA NA NA NA NAWCM154 X 40218561 49034387 0.0419 0.8842 NA NA NA NA WCM154 X 49065850154493598 0.2205 1.1933 NA NA NA NA WCM154_Z1_1 1 69603 16802942 −0.57940.2166 2.2971 0.027 2 0 WCM154_Z1_1 1 16863328 17275305 −1.017 −0.30081.3949 0.2287 1 0 WCM154_Z1_1 1 17277585 28052657 −0.6148 0.1758 2.20970.0495 2 0 WCM154_Z1_1 1 28054037 28290084 0.4196 1.3211 NA NA NA NAWCM154_Z1_1 1 28293068 29365776 −0.0475 0.8146 NA NA NA NA WCM154_Z1_1 129379775 51253762 0.4547 1.3587 2.9099 2.2192 3 2 WCM154_Z1_1 1 5126734955307501 −0.1104 0.7452 2.2894 1.0629 2 1 WCM154_Z1_1 1 5531802465312358 0.4229 1.3247 2.6093 2.4002 3 2 WCM154_Z1_1 1 65313282 66384416−0.1602 0.6901 NA NA NA NA WCM154_Z1_1 1 66458649 72748046 0.408 1.30872.5753 2.379 3 2 WCM154_Z1_1 1 74492554 104163199 −0.3211 0.5105 2.81410.0349 3 0 WCM154_Z1_1 1 107599497 225340563 0.4077 1.3084 2.7792 2.17423 2 WCM154_Z1_1 1 225341507 226187000 −0.1851 0.6624 NA NA NA NAWCM154_Z1_1 1 226253527 249212342 0.1802 1.0633 2.0896 2.0896 2 2WCM154_Z1_1 10 225958 135440068 −0.7717 −0.0072 1.9556 0.0344 2 0WCM154_Z1_1 11 193112 48328644 −0.3469 0.4814 2.6825 0.1097 3 0WCM154_Z1_1 11 48346822 57148170 −0.3921 0.4303 1.7087 0.9863 2 1WCM154_Z1_1 11 57154983 134856626 −0.3491 0.4789 2.6968 0.0904 3 0WCM154_Z1_1 12 148642 29521193 −0.6911 0.0872 2.0546 0.07 2 0WCM154_Z1_1 12 29523114 120128145 0.0792 0.9534 1.9617 1.911 2 2WCM154_Z1_1 12 120135573 120662505 −0.256 0.5834 NA NA NA NA WCM154_Z1_112 120720384 132238926 0.4243 1.3262 2.859 2.1558 3 2 WCM154_Z1_1 12132239988 132633366 −0.212 0.6325 NA NA NA NA WCM154_Z1_1 12 132635585133810874 0.4275 1.3296 2.8872 2.1394 3 2 WCM154_Z1_1 13 1960051536429656 0.3632 1.2607 2.8669 1.9254 3 2 WCM154_Z1_1 13 3644539054886136 −0.3066 0.5267 2.8379 0.0435 3 0 WCM154_Z1_1 13 55748673115089411 0.3527 1.2494 2.7554 1.9995 3 2 WCM154_Z1_1 14 19377718107283092 0.1044 0.9808 1.9908 1.9564 2 2 WCM154_Z1_1 15 2017015923807222 −0.8031 −0.0443 1.3366 0.603 1 1 WCM154_Z1_1 15 23811118102506284 −0.7487 0.0197 1.985 0.0425 2 0 WCM154_Z1_1 16 67604 2581992−0.6968 0.0805 2.0679 0.0469 2 0 WCM154_Z1_1 16 2636684 34256879 0.12551.0038 2.0315 1.9791 2 2 WCM154_Z1_1 16 34257210 90233626 −0.6573 0.12652.1416 0.0416 2 0 WCM154_Z1_1 17 131595 7559174 0.0704 0.9437 3.81140.0356 4 0 WCM154_Z1_1 17 7573966 7579856 −2.4614 −2.4214 NA NA NA NAWCM154_Z1_1 17 7580651 20931872 0.0759 0.9498 3.8141 0.0491 4 0WCM154_Z1_1 17 20946100 21454339 0.1464 1.0266 2.1678 1.9066 2 2WCM154_Z1_1 17 21454552 78237495 0.0707 0.9441 3.7934 0.0546 4 0WCM154_Z1_1 17 78247122 80019506 0.423 1.3248 4.02 0.99 4 1 WCM154_Z1_117 80019857 81083526 0.6458 1.562 3.8101 2.0953 4 2 WCM154_Z1_1 18 4823378005214 0.604 1.5177 2.8634 2.8634 3 3 WCM154_Z1_1 19 281491 590839510.1144 0.9917 2.0037 1.9734 2 2 WCM154_Z1_1 2 41614 69240666 0.05040.9219 2.8121 0.9771 3 1 WCM154_Z1_1 2 69267173 242946607 −0.2925 0.54252.8756 0.0375 3 0 WCM154_Z1_1 20 68351 62904881 −0.1539 0.6971 2.0851.1574 2 1 WCM154_Z1_1 21 9907280 34017281 −0.3865 0.4367 2.6784 0.02853 0 WCM154_Z1_1 21 34017994 34113830 0.1174 0.995 NA NA NA NAWCM154_Z1_1 21 34115350 39817513 0.5473 1.4574 2.7842 2.7082 3 3WCM154_Z1_1 21 39822803 42839766 0.3007 1.1935 2.9916 1.5825 3 2WCM154_Z1_1 21 42840423 48084214 −0.341 0.488 2.7636 0.0414 3 0WCM154_Z1_1 22 16287443 24313782 −0.2118 0.6326 3.0804 0.0204 3 0WCM154_Z1_1 22 24340851 24432609 0.8663 1.7947 NA NA NA NA WCM154_Z1_122 24434805 51219138 −0.2195 0.6241 3.0356 0.0468 3 0 WCM154_Z1_1 3239377 89528644 0.0196 0.8883 1.8854 1.8165 2 2 WCM154_Z1_1 3 93595840105588192 −0.8046 −0.0461 1.9178 0.0193 2 0 WCM154_Z1_1 3 107096547185638927 0.3436 1.2397 2.7878 1.9351 3 2 WCM154_Z1_1 3 185641632197894712 −0.0246 0.8398 1.8055 1.774 2 2 WCM154_Z1_1 4 59434 184633780−0.7804 −0.0175 1.1207 0.8552 1 1 WCM154_Z1_1 4 184827971 190426502−1.4807 −0.8886 1.006 0.0743 1 0 WCM154_Z1_1 5 140621 65004313 0.78941.7139 4.6838 1.8769 5 2 WCM154_Z1_1 5 65008792 74021487 −0.7731 −0.00891.9629 0.0248 2 0 WCM154_Z1_1 5 74021874 82373138 0.7958 1.7205 4.69481.8963 5 2 WCM154_Z1_1 5 82406962 90136712 −0.7972 −0.0374 1.9067 0.04222 0 WCM154_Z1_1 5 90144496 180687814 0.7897 1.7141 4.6604 1.9014 5 2WCM154_Z1_1 6 203615 78173107 0.0614 0.934 1.9523 1.8688 2 2 WCM154_Z1_16 79424433 102516260 −0.6983 0.0788 2.0792 0.0331 2 0 WCM154_Z1_1 6105177568 170893407 0.0407 0.9114 2.066 1.6957 2 2 WCM154_Z1_1 7 193254158937018 −0.226 0.6169 2.0688 0.9983 2 1 WCM154_Z1_1 8 190906 1462794530.3026 1.1955 2.6775 1.903 3 2 WCM154_Z1_1 9 17088 78965806 0.05670.9288 2.6485 1.159 3 1 WCM154_Z1_1 9 78969059 86900926 −0.364 0.46212.7419 0.0131 3 0 WCM154_Z1_1 9 86903030 93657848 0.2809 1.1721 2.82931.6775 3 2 WCM154_Z1_1 9 93976701 95608658 −0.3483 0.4798 2.7912 −0.00213 0 WCM154_Z1_1 9 95608768 95874189 0.4449 1.3483 NA NA NA NAWCM154_Z1_1 9 95874528 130083043 0.3075 1.2008 2.7986 1.7987 3 2WCM154_Z1_1 9 130087356 141111414 0.3918 1.2914 2.7652 2.1301 3 2WCM154_Z1_1 X 2707711 38664643 0.0263 0.8956 NA NA NA NA WCM154_Z1_1 X39696863 40450579 −2.3745 −2.2569 NA NA NA NA WCM154_Z1_1 X 40456505154509348 0.0915 0.9668 NA NA NA NA WCM155 1 17453 22987613 −0.37 0.15861.1162 1.1162 1 1 WCM155 1 22987765 26131804 −1.1442 −0.9594 0.99910.0294 1 0 WCM155 1 26135250 31192678 −0.2998 0.2492 1.2159 1.1611 1 1WCM155 1 31194308 249213973 0.2303 0.8986 2.6993 1.0292 3 1 WCM155 10225936 2056415 0.3275 1.0125 NA NA NA NA WCM155 10 3111625 57359679−0.2476 0.3157 2.4044 0.0848 2 0 WCM155 10 58117959 60124557 −2.4118−5.7406 NA NA NA NA WCM155 10 60127688 61554414 −0.2768 0.2785 NA NA NANA WCM155 10 61564204 88760258 0.1477 0.8007 2.4289 1.055 2 1 WCM155 1088761503 89603915 −0.1829 0.3971 NA NA NA NA WCM155 10 89621724 90074395−2.1402 −3.448 NA NA NA NA WCM155 10 90122345 135477904 −0.2068 0.36722.5429 0.0367 3 0 WCM155 11 193096 134605954 −0.1116 0.486 1.7109 1.09022 1 WCM155 12 148430 16757863 −0.4379 0.0698 2.0549 0.0442 2 0 WCM155 1218234316 22843284 0.5247 1.2399 2.5019 2.2216 3 2 WCM155 12 2284356934180172 −0.4867 0.0051 1.9327 0.0744 2 0 WCM155 12 34180370 1040320320.3364 1.0228 2.0319 2.0319 2 2 WCM155 12 104034050 133810880 −0.37240.1555 2.2049 0.0227 2 0 WCM155 13 19041937 47315970 −0.0569 0.55342.9083 0.0268 3 0 WCM155 13 47317388 47367537 −2.0257 −2.9802 NA NA NANA WCM155 13 47396144 115089411 −0.0504 0.5614 2.9049 0.0466 3 0 WCM15514 19110239 107283270 0.6165 1.3441 3.1994 1.8782 3 2 WCM155 15 2008396822933511 −0.4535 0.0492 1.6776 0.3917 2 0 WCM155 15 22933760 102514218−0.4674 0.0308 1.9972 0.0461 2 0 WCM155 16 97584 10274308 −0.0506 0.56121.8065 1.1444 2 1 WCM155 16 10275755 11876217 −1.1254 −0.9287 1.00960.0411 1 0 WCM155 16 11913796 30129735 −0.1537 0.4337 1.6555 1.0459 2 1WCM155 16 30133298 31044683 −1.2245 −1.0944 0.959 −0.0223 1 0 WCM155 1631045168 48204077 −0.1076 0.4909 1.5983 1.2123 2 1 WCM155 16 4820483257017527 −0.5169 −0.0352 1.9185 0.0332 2 0 WCM155 16 57051133 74446830−0.0789 0.5264 1.6833 1.1973 2 1 WCM155 16 74447064 90260461 −0.48770.0038 1.9739 0.0314 2 0 WCM155 17 131595 27577326 0.1653 0.8216 1.76741.7674 2 2 WCM155 17 27579045 40975970 −0.5066 −0.0215 1.9161 0.0543 2 0WCM155 17 40976245 81187854 0.2546 0.9272 1.9015 1.9015 2 2 WCM155 1847711 50683793 −0.0506 0.5612 1.7179 1.2331 2 1 WCM155 18 5070536178005226 −0.9699 −0.6825 1.2381 0.0081 1 0 WCM155 19 105050 40196683−0.0482 0.5641 1.5111 1.4459 2 1 WCM155 19 40197328 42713835 0.27740.9539 2.6409 1.2333 3 1 WCM155 19 42719324 42806483 −0.8862 −0.556 NANA NA NA WCM155 19 42813884 46444066 0.0109 0.6362 1.5845 1.5241 2 2WCM155 19 46457052 47217284 −0.6034 −0.1524 1.8097 −0.0103 2 0 WCM155 1947219499 59093645 0.0655 0.7022 1.627 1.627 2 2 WCM155 2 41615 14777883−0.5084 −0.0238 0.9836 0.9836 1 1 WCM155 2 14778142 187498107 −0.24210.3226 1.2506 1.2506 1 1 WCM155 2 187500767 243036958 −0.4498 0.05411.0382 1.0382 1 1 WCM155 20 68311 62934623 0.1446 0.7971 1.7376 1.7376 22 WCM155 21 9590370 48084114 0.4988 1.2102 2.7954 1.8319 3 2 WCM155 2216159044 46486943 −0.4567 0.045 2.0144 0.0489 2 0 WCM155 22 4649374151223730 0.2871 0.9653 1.9525 1.9525 2 2 WCM155 3 239451 9547806 0.16590.8224 1.7683 1.7683 2 2 WCM155 3 9594037 11888165 −0.4936 −0.004 1.98450.0099 2 0 WCM155 3 11902005 70017107 0.2231 0.8901 1.8534 1.8534 2 2WCM155 3 70017459 72311601 −0.7385 −0.341 NA NA NA NA WCM155 3 72423904197896800 0.1981 0.8605 1.8157 1.8157 2 2 WCM155 4 53336 17963681 −0.4760.0194 1.0135 1.0135 1 1 WCM155 4 17964594 42965095 −1.1945 −1.04340.9599 0.0104 1 0 WCM155 4 43022362 146086293 −0.5093 −0.025 0.98280.9828 1 1 WCM155 4 146092923 147863881 −1.1618 −0.9886 NA NA NA NAWCM155 4 148265864 190903996 −0.5272 −0.049 0.9666 0.9666 1 1 WCM155 590537 180687847 −0.111 0.4867 1.7169 1.0855 2 1 WCM155 6 203588 738795280.1941 0.8558 2.6414 0.9783 3 1 WCM155 6 73900433 117249987 −0.16390.4209 2.6564 0.0212 3 0 WCM155 6 117250139 170892860 0.1441 0.79642.5234 0.9501 3 1 WCM155 7 193254 141628158 −0.109 0.4892 1.7198 1.08752 1 WCM155 7 141629933 158937046 0.4981 1.2094 2.6643 1.9605 3 2 WCM1558 163470 7631260 −0.5384 −0.0641 1.8801 0.033 2 0 WCM155 8 77178958086107 −2.3362 −4.7314 NA NA NA NA WCM155 8 8090350 42698270 −0.5063−0.0211 1.9351 0.0359 2 0 WCM155 8 42705973 146279528 0.4174 1.11682.1686 2.1686 2 2 WCM155 9 14908 21512219 −0.5111 −0.0274 1.9066 0.05582 0 WCM155 9 21802811 23815002 −2.3709 −5.1165 NA NA NA NA WCM155 924543350 27567137 −0.605 −0.1547 1.8319 −0.0353 2 0 WCM155 9 27610103141107536 0.2373 0.9068 1.8749 1.8749 2 2 WCM155 X 2700084 1544935980.1189 0.7664 NA NA NA NA WCM155_Z1_1 1 69634 22336336 −0.6878 −0.03391.0463 0.9073 1 1 WCM155_Z1_1 1 22405202 22834595 −1.5575 −0.9418 NA NANA NA WCM155_Z1_1 1 22835077 22987537 −0.6586 −0.0037 NA NA NA NAWCM155_Z1_1 1 22987618 26131654 −1.6325 −1.0214 0.9958 −0.0105 1 0WCM155_Z1_1 1 26135156 29863127 −0.1748 0.4928 1.8228 0.9916 2 1WCM155_Z1_1 1 31186459 154033493 0.2943 0.9707 2.9252 0.9943 3 1WCM155_Z1_1 1 154042912 154293675 1.0722 1.758 NA NA NA NA WCM155_Z1_1 1154294529 249212401 0.2758 0.9518 2.9268 0.9419 3 1 WCM155_Z1_1 10225979 1599093 0.576 1.2563 NA NA NA NA WCM155_Z1_1 10 1779275 61552524−0.2249 0.4416 2.7193 −0.0031 3 0 WCM155_Z1_1 10 61552637 887305000.2283 0.9036 2.8235 0.918 3 1 WCM155_Z1_1 10 88764111 135440068 −0.18640.4809 2.7937 −0.0024 3 0 WCM155_Z1_1 11 193112 134856626 −0.1485 0.51961.8934 0.9737 2 1 WCM155_Z1_1 12 148644 17826233 −0.4963 0.1634 2.2477−0.0079 2 0 WCM155_Z1_1 12 18234288 22837880 0.5777 1.2581 2.4354 2.34822 2 WCM155_Z1_1 12 23686050 34182560 −0.5584 0.0995 2.1517 −0.0089 2 0WCM155_Z1_1 12 38710847 49920023 0.3228 0.9996 2.0868 1.9121 2 2WCM155_Z1_1 12 49933229 80837600 0.4244 1.1028 2.1477 2.1477 2 2WCM155_Z1_1 12 80838125 104034014 0.3651 1.0425 2.1581 1.9615 2 2WCM155_Z1_1 12 104042576 133810926 −0.574 0.0834 2.1173 0.0018 2 0WCM155_Z1_1 13 19600159 115089411 −0.0979 0.5713 2.9724 −6.00E−04  3 0WCM155_Z1_1 14 19377727 107283047 0.7687 1.4514 3.7719 1.6976 4 2WCM155_Z1_1 15 20170150 102517642 −0.6963 −0.0426 1.9427 −9.00E−04  2 0WCM155_Z1_1 16 97486 10274203 −0.1249 0.5438 1.9223 0.9933 2 1WCM155_Z1_1 16 10524563 11914071 −1.6181 −1.0061 1.0098 −0.014 1 0WCM155_Z1_1 16 11931840 30194351 −0.1577 0.5102 1.8594 0.9892 2 1WCM155_Z1_1 16 30196714 31012907 −1.6152 −1.003 0.9928 0.0051 1 0WCM155_Z1_1 16 31045389 48204026 −0.1533 0.5147 1.8681 0.9894 2 1WCM155_Z1_1 16 48204820 57054762 −0.6796 −0.0254 1.9758 −0.0107 2 0WCM155_Z1_1 16 57056170 74366531 −0.0484 0.6219 2.0616 1.0161 2 1WCM155_Z1_1 16 74371376 90233622 −0.5347 0.1238 2.1765 0.0027 2 0WCM155_Z1_1 17 131595 27493713 0.1593 0.8334 1.8037 1.7602 2 2WCM155_Z1_1 17 27493802 40972815 −0.6837 −0.0296 1.959 4.00E−04 2 0WCM155_Z1_1 17 40975773 81083561 0.3846 1.0624 2.1138 2.0629 2 2WCM155_Z1_1 18 48202 50592427 −0.0965 0.5728 1.9155 1.0592 2 1WCM155_Z1_1 18 50683803 64235922 −1.5413 −0.9247 1.0689 −0.0153 1 0WCM155_Z1_1 18 64239283 66678298 −0.1658 0.5019 NA NA NA NA WCM155_Z1_118 67068541 70532137 −1.5374 −0.9205 NA NA NA NA WCM155_Z1_1 18 7053244178005206 −0.8013 −0.151 1.8023 −0.0011 2 0 WCM155_Z1_1 19 28141540276696 −0.1425 0.5258 1.9147 0.9647 2 1 WCM155_Z1_1 19 4031635842626711 0.2755 0.9516 2.9105 0.9574 3 1 WCM155_Z1_1 19 4263654342806417 −1.6452 −1.0348 NA NA NA NA WCM155_Z1_1 19 42813955 46417907−0.1479 0.5202 1.8942 0.9741 2 1 WCM155_Z1_1 19 46443397 47219580−0.7699 −0.1186 1.8502 −0.0081 2 0 WCM155_Z1_1 19 47223949 590839880.2182 0.8933 1.882 1.8329 2 2 WCM155_Z1_1 2 41620 15307391 −0.6807−0.0265 1.0082 0.9555 1 1 WCM155_Z1_1 2 15307442 186696610 −0.18980.4775 1.825 0.9597 2 1 WCM155_Z1_1 2 186697938 201541625 −0.7019−0.0484 1.0828 0.8513 1 1 WCM155_Z1_1 2 201677131 201760020 −1.6823−1.0744 NA NA NA NA WCM155_Z1_1 2 201761859 242946616 −0.7024 −0.04891.0584 0.8749 1 1 WCM155_Z1_1 20 68406 62904845 0.2413 0.9168 1.88791.8879 2 2 WCM155_Z1_1 21 9826235 48084282 0.6209 1.3018 3.0745 1.8563 32 WCM155_Z1_1 22 17063476 46449629 −0.6842 −0.0302 1.9592 −6.00E−04  2 0WCM155_Z1_1 22 46449924 51219138 0.1809 0.8554 1.8534 1.7651 2 2WCM155_Z1_1 3 239431 9543958 0.3152 0.9919 1.9968 1.9807 2 2 WCM155_Z1_13 9547696 11887993 −0.5619 0.0959 2.1464 −0.0089 2 0 WCM155_Z1_1 312046076 69998309 0.3142 0.9908 2.0095 1.9651 2 2 WCM155_Z1_1 3 7000099571834110 −0.6288 0.027 NA NA NA NA WCM155_Z1_1 3 72427727 1978947120.2971 0.9734 1.9755 1.9516 2 2 WCM155_Z1_1 4 59334 17887713 −0.6876−0.0336 1.0506 0.9034 1 1 WCM155_Z1_1 4 17910840 43032460 −1.6182−1.0063 0.9986 −0.0029 1 0 WCM155_Z1_1 4 44176927 146475191 −0.7165−0.0635 0.9797 0.9342 1 1 WCM155_Z1_1 4 146478954 148265854 −1.5998−0.9867 NA NA NA NA WCM155_Z1_1 4 148406880 190426471 −0.7164 −0.06330.9847 0.9294 1 1 WCM155_Z1_1 5 140480 180687800 −0.1883 0.479 1.83120.9564 2 1 WCM155_Z1_1 6 203583 73904476 0.2396 0.9151 2.8651 0.9063 3 1WCM155_Z1_1 6 73904851 117589385 −0.178 0.4895 2.8101 −0.0022 3 0WCM155_Z1_1 6 117589621 170893415 0.2196 0.8947 2.7855 0.9331 3 1WCM155_Z1_1 7 193254 141619380 −0.1434 0.5248 1.8988 0.9787 2 1WCM155_Z1_1 7 141629934 158937400 0.5833 1.2638 2.9387 1.8637 3 2WCM155_Z1_1 8 190907 42698213 −0.8305 −0.1813 1.7674 −0.0035 2 0WCM155_Z1_1 8 42705962 146279545 0.2674 0.9433 2.0969 1.7491 2 2WCM155_Z1_1 9 17079 27949279 −0.7122 −0.0591 1.9309 −0.0111 2 0WCM155_Z1_1 9 27949467 141111414 0.2328 0.9082 1.8767 1.8767 2 2WCM155_Z1_1 X 2700159 154509348 −0.0109 0.6601 NA NA NA NA WCM155_Z2_1 169610 22987834 −0.5832 −0.0243 1.0793 0.8873 1 1 WCM155_Z2_1 1 2304605826131654 −1.0756 −0.7836 1.124 0.0377 1 0 WCM155_Z2_1 1 2613507529475580 −0.1314 0.5803 1.9044 1.0859 2 1 WCM155_Z2_1 1 29476670249212388 0.2268 1.0227 3.0907 0.9727 3 1 WCM155_Z2_1 10 225979 31431150.4606 1.2992 NA NA NA NA WCM155_Z2_1 10 3143624 57359707 −0.1131 0.60353.0386 3.00E−04 3 0 WCM155_Z2_1 10 58117933 60128497 −1.8535 −2.5689 NANA NA NA WCM155_Z2_1 10 60145356 61552397 −0.2131 0.4755 NA NA NA NAWCM155_Z2_1 10 61552694 88811601 0.2616 1.0644 3.0786 1.1039 3 1WCM155_Z2_1 10 88813150 135440117 −0.1151 0.601 3.0338 −3.00E−04  3 0WCM155_Z2_1 11 193112 61036462 −0.1146 0.6016 2.0239 1.0109 2 1WCM155_Z2_1 11 61039162 85576181 −0.0771 0.649 2.1176 1.0186 2 1WCM155_Z2_1 11 85584303 134856626 −0.1335 0.5776 2.0018 0.9829 2 1WCM155_Z2_1 12 148637 17826293 −0.4945 0.0997 2.106 0.037 2 0WCM155_Z2_1 12 18234236 22837885 0.2213 1.016 2.0831 1.9615 2 2WCM155_Z2_1 12 23686046 34182560 −0.579 −0.0183 1.9993 −0.0246 2 0WCM155_Z2_1 12 38710800 104033980 0.2318 1.0286 2.0499 2.0303 2 2WCM155_Z2_1 12 104042484 133810794 −0.5525 0.019 2.0241 0.0024 2 0WCM155_Z2_1 13 19600147 115089411 −0.0755 0.6511 3.1435 −0.0028 3 0WCM155_Z2_1 14 19377733 107283060 0.4341 1.2682 2.9213 1.8959 3 2WCM155_Z2_1 15 20170150 102517639 −0.5598 0.0087 2.0061 0.006 2 0WCM155_Z2_1 16 97464 10775855 −0.1843 0.5126 1.8927 0.9605 2 1WCM155_Z2_1 16 10783119 11868148 −1.2348 −1.0665 NA NA NA NA WCM155_Z2_116 11868856 30199807 −0.5731 −0.01 1.0113 0.9749 1 1 WCM155_Z2_1 1630217373 31051114 −1.096 −0.8186 1.0664 0.0676 1 0 WCM155_Z2_1 1631072510 48177864 −0.1824 0.515 1.8975 0.9604 2 1 WCM155_Z2_1 1648180277 57054692 −0.5821 −0.0227 1.9956 −0.0268 2 0 WCM155_Z2_1 1657056167 74366531 −0.1414 0.5675 1.9981 0.9659 2 1 WCM155_Z2_1 1674371512 90233622 −0.6065 −0.0574 1.9484 −0.0264 2 0 WCM155_Z2_1 17131595 27493920 0.0964 0.8645 1.8386 1.8029 2 2 WCM155_Z2_1 17 2757388640972834 −0.5558 0.0143 2.0284 −0.0085 2 0 WCM155_Z2_1 17 4097579681083561 0.2017 0.9924 1.9895 1.9895 2 2 WCM155_Z2_1 18 48202 50592425−0.126 0.5872 1.9532 1.0514 2 1 WCM155_Z2_1 18 50683882 71803073 −1.0917−0.8113 1.1167 0.023 1 0 WCM155_Z2_1 18 71807493 78005164 −0.5944−0.0402 1.8715 0.0735 2 0 WCM155_Z2_1 19 281535 40317363 −0.1902 0.5051.8668 0.9713 2 1 WCM155_Z2_1 19 40318021 42621152 0.2477 1.0477 3.17390.9606 3 1 WCM155_Z2_1 19 42621404 42806423 −0.9569 −0.5871 NA NA NA NAWCM155_Z2_1 19 42813797 46444058 −0.1707 0.5301 1.8627 1.0254 2 1WCM155_Z2_1 19 46444177 47242116 −0.6074 −0.0587 1.9934 −0.0731 2 0WCM155_Z2_1 19 47258832 59083988 0.1133 0.8852 1.8628 1.8313 2 2WCM155_Z2_1 2 41614 11800179 −0.6001 −0.0482 1.0015 0.9327 1 1WCM155_Z2_1 2 11802135 186666103 −0.1853 0.5112 1.8562 0.9944 2 1WCM155_Z2_1 2 186666414 242946607 −0.5885 −0.0317 0.9935 0.963 1 1WCM155_Z2_1 20 68397 62904881 −0.1209 0.5936 1.9787 1.0392 2 1WCM155_Z2_1 21 9826230 48084214 0.1357 0.9124 1.896 1.8685 2 2WCM155_Z2_1 22 17063431 46494384 −0.566 −1.00E−04 2.021 −0.0211 2 0WCM155_Z2_1 22 46501443 51219138 0.1487 0.9283 1.9678 1.8384 2 2WCM155_Z2_1 3 239451 9547837 −0.1549 0.5503 1.9719 0.9569 2 1WCM155_Z2_1 3 9594120 12278890 −0.5265 0.0554 1.9511 0.1271 2 0WCM155_Z2_1 3 12393092 197894712 −0.1461 0.5616 1.9978 0.9539 2 1WCM155_Z2_1 4 59390 20552510 −0.556 0.014 1.0282 0.9913 1 1 WCM155_Z2_14 20555479 42658879 −1.205 −1.0116 0.9799 0.0121 1 0 WCM155_Z2_1 442895389 190426471 −0.5324 0.0471 1.0606 1.0058 1 1 WCM155_Z2_1 5 140443180687800 −0.1187 0.5964 2.0363 0.9877 2 1 WCM155_Z2_1 6 203588 737870850.194 0.9831 2.9666 0.9869 3 1 WCM155_Z2_1 6 73787517 117589463 −0.11680.5988 3.0393 −0.0104 3 0 WCM155_Z2_1 6 117589612 170893427 0.21151.0042 2.9908 1.0208 3 1 WCM155_Z2_1 7 193245 141635637 −0.1143 0.60211.9744 1.0613 2 1 WCM155_Z2_1 7 141643719 158937400 0.4544 1.2919 2.96861.9286 3 2 WCM155_Z2_1 8 190900 42693429 −0.5512 0.0208 2.0149 0.0142 20 WCM155_Z2_1 8 42694404 146279507 0.1917 0.9804 1.9849 1.9611 2 2WCM155_Z2_1 9 17053 27949026 −0.5349 0.0436 2.0236 0.0377 2 0WCM155_Z2_1 9 27949189 141111414 0.1724 0.957 1.9413 1.9413 2 2WCM155_Z2_1 X 2700147 154509348 0.2048 0.9962 NA NA NA NA WCM156 1 14896117120081 −0.008 0.0593 1.042 1.042 1 1 WCM156 1 117122058 1607843360.1167 0.9622 1.9483 1.9483 2 2 WCM156 1 160786632 197404692 −0.016−0.0196 0.9865 0.9865 1 1 WCM156 1 197407787 248512064 0.1049 0.89451.8589 1.8589 2 2 WCM156 1 248512498 249213961 0.0101 0.2244 2.5004−0.1637 3 0 WCM156 10 225938 135439032 −0.0413 −0.3 0.8122 0.8122 1 1WCM156 11 193096 134605906 −0.0123 0.0173 1.0121 1.0121 1 1 WCM156 12148452 133810880 −0.0232 −0.0948 0.9364 0.9364 1 1 WCM156 13 1904200529012330 −0.0107 0.033 1.0232 1.0232 1 1 WCM156 13 29040947 74268850−0.1602 −4.7778 0.0365 0.0365 0 0 WCM156 13 74269160 115089411 0.07150.6874 1.6104 1.6104 2 2 WCM156 14 19110239 107283263 −0.1003 −1.25360.4194 0.4194 0 0 WCM156 15 20083896 35664328 0.0197 0.3059 1.23611.2361 1 1 WCM156 15 35664559 53081788 −0.1384 −2.5234 0.1739 0.1739 0 0WCM156 15 53176757 102515241 −0.0018 0.118 1.0852 1.0852 1 1 WCM156 1664430 90168697 −0.0405 −0.2899 0.818 0.818 1 1 WCM156 17 131595 8445626−0.166 −11.7873 3.00E−04 3.00E−04 0 0 WCM156 17 8448822 81052545 0.02060.3132 1.2425 1.2425 1 1 WCM156 18 47682 78005145 −0.0406 −0.2914 0.81710.8171 1 1 WCM156 19 105050 59093645 −0.0067 0.0711 1.0505 1.0505 1 1WCM156 2 41613 243037091 0.007 0.1977 1.1468 1.1468 1 1 WCM156 20 6831262934623 −1.00E−04 0.1332 1.0967 1.0967 1 1 WCM156 21 9590311 48084210−0.0459 −0.3564 0.7811 0.7811 1 1 WCM156 22 16159043 51219090 0.01040.2269 1.1703 1.1703 1 1 WCM156 3 239459 113505143 −0.0402 −0.28580.8203 0.8203 1 1 WCM156 3 113505277 173999810 0.078 0.7297 1.65831.6583 2 2 WCM156 3 174000019 197896708 −0.0262 −0.1271 0.9157 0.9157 11 WCM156 4 53361 190878508 −0.0301 −0.1697 0.889 0.889 1 1 WCM156 590680 180687854 −0.0398 −0.2815 0.8227 0.8227 1 1 WCM156 6 20347576388512 0.0313 0.3998 1.3193 1.3193 1 1 WCM156 6 76388561 170892712−0.1023 −1.2997 0.4062 0.4062 0 0 WCM156 7 193205 158937135 −0.0241−0.1044 0.9302 0.9302 1 1 WCM156 8 163438 68110923 −0.0783 −0.82650.5639 0.5639 1 1 WCM156 8 68111147 146279396 0.093 0.8239 1.7702 1.77022 2 WCM156 9 116808 141107525 0.0353 0.4306 1.3478 1.3478 1 1 WCM156 X2700162 154493589 −0.1808 NA NA NA NA NA WCM156_Z5_1 1 721439 878434−0.1011 −0.1138 NA NA NA NA WCM156_Z5_1 1 878734 11276286 −0.4587−0.9475 1.0288 0.0082 1 0 WCM156_Z5_1 1 11288758 93302926 −0.0403 0.00521.0171 0.9901 1 1 WCM156_Z5_1 1 93303154 95360379 −0.4945 −1.0493 NA NANA NA WCM156_Z5_1 1 95363337 145699074 −0.0583 −0.0296 1.0196 0.9397 1 1WCM156_Z5_1 1 145704016 160771581 0.3051 0.6086 1.9727 1.0768 2 1WCM156_Z5_1 1 160783679 190250846 −0.0741 −0.0605 1.994 −0.0762 2 0WCM156_Z5_1 1 190423929 249212346 0.2803 0.5685 2.9796 −0.0136 3 0WCM156_Z5_1 10 225980 24762793 −0.4892 −1.034 1.0798 −0.103 1 0WCM156_Z5_1 10 24762971 87675947 −0.0428  3.00E−04 1.0502 0.9502 1 1WCM156_Z5_1 10 87898734 96234541 −0.4745 −0.9919 1.0162 −0.0105 1 0WCM156_Z5_1 10 96253145 104934633 −0.0545 −0.0222 1.0115 0.958 1 1WCM156_Z5_1 10 105005970 105386870 0.3345 0.6554 NA NA NA NA WCM156_Z5_110 105420796 129923888 −0.0432 −3.00E−04 0.9998 0.9998 1 1 WCM156_Z5_110 131265549 135440080 −0.4215 −0.8464 1.0843 0.0281 1 0 WCM156_Z5_1 11193127 134856597 −0.0386 0.0085 1.0233 0.9885 1 1 WCM156_Z5_1 12 14863968042938 −0.0548 −0.0228 1.0053 0.9634 1 1 WCM156_Z5_1 12 6804359280602001 1.0459 1.6633 5.3723 0.9627 5 1 WCM156_Z5_1 12 80603289133810704 0.2831 0.5731 3.0138 −0.0383 3 0 WCM156_Z5_1 13 1960015931543095 −0.0863 −0.0845 0.9879 0.8983 1 1 WCM156_Z5_1 13 3154901731903679 −0.3719 −0.718 NA NA NA NA WCM156_Z5_1 13 32313822 33226096−1.1235 NA NA NA NA NA WCM156_Z5_1 13 33226199 73649950 −0.4022 −0.79561.2357 −0.0835 1 0 WCM156_Z5_1 13 74269778 88330464 0.0682 0.2067 1.261.0481 1 1 WCM156_Z5_1 13 90883524 115039326 0.3559 0.6893 2.074 1.151 21 WCM156_Z5_1 13 115047220 115089411 0.1095 0.2802 NA NA NA NAWCM156_Z5_1 14 19377710 33004964 0.2723 0.5555 1.9746 0.9648 2 1WCM156_Z5_1 14 33005011 107283027 −0.0466 −0.0069 1.9736 0.0169 2 0WCM156_Z5_1 15 20170091 35834654 −0.0215 0.0411 1.3548 0.7029 1 1WCM156_Z5_1 15 36219092 54786879 −0.4919 −1.0416 0.962 0.0096 1 0WCM156_Z5_1 15 54792371 102517666 −0.033 0.0192 1.0424 0.9843 1 1WCM156_Z5_1 16 67604 69972998 −0.041 0.0038 1.018 0.9872 1 1 WCM156_Z5_116 69973304 90233642 −0.4661 −0.9681 0.9945 0.0278 1 0 WCM156_Z5_1 17131595 14683390 −0.479 −1.0045 0.996 9.00E−04 1 0 WCM156_Z5_1 1715134287 71197439 −0.0444 −0.0026 1.0155 0.9809 1 1 WCM156_Z5_1 1771197707 81083507 0.3202 0.6328 2.018 1.083 2 1 WCM156_Z5_1 18 4827278005224 −0.0435 −0.001 1.0166 0.982 1 1 WCM156_Z5_1 19 281467 59083951−0.0446 −0.0031 1.0132 0.9825 1 1 WCM156_Z5_1 2 41613 242946604 −0.0454−0.0046 1.0103 0.9834 1 1 WCM156_Z5_1 20 68373 3190210 0.3026 0.60462.0337 1.0074 2 1 WCM156_Z5_1 20 3193978 62904845 −0.0258 0.0328 1.04640.9997 1 1 WCM156_Z5_1 21 9826235 39672220 −0.055 −0.0232 1.1938 0.77421 1 WCM156_Z5_1 21 39755581 42870049 −0.4392 −0.8939 1.0715 0.0048 1 0WCM156_Z5_1 21 43133121 48084204 −0.0181 0.0475 1.0687 0.9983 1 1WCM156_Z5_1 22 16287470 51219138 −0.0485 −0.0106 1.0157 0.9697 1 1WCM156_Z5_1 3 239443 117716044 −0.0415 0.0029 1.0155 0.9886 1 1WCM156_Z5_1 3 118227497 171087418 0.276 0.5615 1.9268 1.0249 2 1WCM156_Z5_1 3 171321030 197894712 −0.0591 −0.031 1.0148 0.9426 1 1WCM156_Z5_1 4 59326 190426471 −0.0551 −0.0234 1.0049 0.9629 1 1WCM156_Z5_1 5 140532 66479914 −0.0491 −0.0118 1.0263 0.9574 1 1WCM156_Z5_1 5 66480145 94417174 −0.5095 −1.0932 0.9739 −0.0365 1 0WCM156_Z5_1 5 94619615 180687804 −0.047 −0.0078 2.0129 −0.0237 2 0WCM156_Z5_1 6 203542 367352 0.4145 0.7804 NA NA NA NA WCM156_Z5_1 6393317 32729453 0.5063 0.9192 2.9604 0.8217 3 1 WCM156_Z5_1 6 32729693108840919 0.2773 0.5637 1.9967 0.9594 2 1 WCM156_Z5_1 6 108843583119226912 −0.5058 −1.0825 0.9285 0.016 1 0 WCM156_Z5_1 6 119228683148664338 0.2682 0.5489 1.8161 1.1098 2 1 WCM156_Z5_1 6 148701057170893389 −0.4759 −0.9959 0.9858 0.0171 1 0 WCM156_Z5_1 7 19326572413593 −0.0382 0.0093 1.0296 0.9833 1 1 WCM156_Z5_1 7 7241668884751079 0.282 0.5714 1.9774 0.9945 2 1 WCM156_Z5_1 7 86274161 140912423−0.0555 −0.0242 1.195 0.7717 1 1 WCM156_Z5_1 7 141137460 1589373750.2953 0.5928 1.9823 1.0341 2 1 WCM156_Z5_1 8 190907 32621337 −0.4372−0.8883 1.0861 −0.0056 1 0 WCM156_Z5_1 8 32621531 68939483 −0.0464−0.0066 1.0587 0.9321 1 1 WCM156_Z5_1 8 68942754 146279480 0.3028 0.60491.9803 1.0614 2 1 WCM156_Z5_1 9 17073 141111414 −0.0316 0.0219 1.01531.0153 1 1 WCM156_Z5_1 X 2700122 2836047 0.079 0.2261 NA NA NA NAWCM156_Z5_1 X 2836138 135961265 −0.0891 −0.0901 NA NA NA NA WCM156_Z5_1X 135961583 154509348 0.5129 0.929 NA NA NA NA WCM158 1 14907 672070670.0758 0.1394 1.1014 1.1014 1 1 WCM158 1 67208729 156314467 −0.0032−0.2283 0.8537 0.8537 1 1 WCM158 1 156314539 200635440 0.0618 0.07921.0564 1.0564 1 1 WCM158 1 200635617 207651294 0.2014 0.6078 1.52391.5239 2 2 WCM158 1 207651437 249213967 0.0076 −0.1733 0.8868 0.8868 1 1WCM158 10 226100 135438946 0.0517 0.0345 1.0242 1.0242 1 1 WCM158 11193112 18045429 0.0941 0.2148 1.1605 1.1605 1 1 WCM158 11 18047284117152292 −0.012 −0.2743 0.8268 0.8268 1 1 WCM158 11 117152674 1346059540.0926 0.2089 1.1558 1.1558 1 1 WCM158 12 148444 51851126 0.0409 −0.01390.9904 0.9904 1 1 WCM158 12 51852444 53346667 0.2767 0.8443 1.79541.7954 2 2 WCM158 12 53400263 133810780 −0.0152 −0.2911 0.8173 0.8173 11 WCM158 13 19042044 115089411 0.0092 −0.1656 0.8915 0.8915 1 1 WCM15814 19110188 107283266 0.0193 −0.116 0.9228 0.9228 1 1 WCM158 15 20083910102514187 0.065 0.0933 1.0668 1.0668 1 1 WCM158 16 64396 90260461 −0.019−0.3118 0.8056 0.8056 1 1 WCM158 17 131595 81187855 0.0297 −0.06610.9552 0.9552 1 1 WCM158 18 47725 78005282 0.0223 −0.1014 0.9321 0.93211 1 WCM158 19 105050 59093645 −0.07 −0.6112 0.6547 0.6547 1 1 WCM158 241609 243052790 0.0187 −0.1187 0.921 0.921 1 1 WCM158 20 68375 629345720.0478 0.0172 1.012 1.012 1 1 WCM158 21 9590370 42080352 −0.0392 −0.42430.7452 0.7452 1 1 WCM158 21 42080666 47639391 0.1809 0.5385 1.45251.4525 1 1 WCM158 21 47641788 48084160 −0.1233 −0.993 NA NA NA NA WCM15822 16159016 51219090 0.0835 0.1715 1.1262 1.1262 1 1 WCM158 3 239451197896800 0.0217 −0.104 0.9304 0.9304 1 1 WCM158 4 53363 190878508−0.0011 −0.2175 0.86 0.86 1 1 WCM158 5 90697 139884482 −0.0092 −0.25930.8355 0.8355 1 1 WCM158 5 139884860 140799205 −0.2664 −3.0565 0.22280.0176 0 0 WCM158 5 140799403 180687812 0.0431 −0.0041 0.9971 0.9971 1 1WCM158 6 203424 170892854 0.0184 −0.12 0.9202 0.9202 1 1 WCM158 7 193189158937074 0.0039 −0.1919 0.8755 0.8755 1 1 WCM158 8 163457 1462794410.006 −0.1816 0.8817 0.8817 1 1 WCM158 9 14859 141107535 0.043 −0.00460.9968 0.9968 1 1 WCM158 X 2700139 154493576 −0.1172 −0.9452 NA NA NA NAWCM158_X1_1 1 721439 1289006 0.0934 1.0785 3.0498 1.1739 3 1 WCM158_X1_11 1289427 2526275 −0.0565 0.7428 1.8097 1.5372 2 2 WCM158_X1_1 1 252674612157172 −0.2809 0.1326 2.0291 0.1634 2 0 WCM158_X1_1 1 12164521120612005 −0.1233 0.5773 1.9741 1.0101 2 1 WCM158_X1_1 1 143767848249212420 0.2079 1.3098 2.9795 1.9786 3 2 WCM158_X1_1 10 225995 3151636−0.3272 −0.0176 NA NA NA NA WCM158_X1_1 10 3154460 42916228  4.00E−040.8755 1.943 1.7262 2 2 WCM158_X1_1 10 42920832 59956205 −0.0567 0.74213.5554 −0.2102 4 0 WCM158_X1_1 10 59956439 88836391 0.2111 1.3162 3.69111.289 4 1 WCM158_X1_1 10 88853704 89550161 −0.089 0.6637 NA NA NA NAWCM158_X1_1 10 89552500 105039713 −0.325 −0.0102 2.1172 −0.1313 2 0WCM158_X1_1 10 105046794 105128296 0.1119 1.1172 NA NA NA NA WCM158_X1_110 105133344 123727226 0.284 1.4541 2.9884 2.4912 3 2 WCM158_X1_1 10123733594 135440090 0.1566 1.2086 3.5651 1.0571 4 1 WCM158_X1_1 11193151 1017893 0.1311 1.1569 2.8914 1.5681 3 2 WCM158_X1_1 11 10182951575841 0.2238 1.3406 3.3987 1.6665 3 2 WCM158_X1_1 11 1576205 1348565620.0486 0.9827 2.0322 1.9201 2 2 WCM158_X1_1 12 148637 10224112 0.10491.1026 2.264 2.031 2 2 WCM158_X1_1 12 10225907 18234256 −0.3448 −0.07782.145 −0.25 2 0 WCM158_X1_1 12 18234384 21448664 −0.9182 NA 0.059−0.3159 0 0 WCM158_X1_1 12 21450349 23687226 −0.3261 −0.0139 NA NA NA NAWCM158_X1_1 12 23687449 33576943 0.0131 0.904 1.9721 1.7703 2 2WCM158_X1_1 12 33579278 41903632 −0.4591 −0.5194 1.4069 −0.0116 1 0WCM158_X1_1 12 41946539 96377687 0.0318 0.9457 2.0028 1.8494 2 2WCM158_X1_1 12 96379914 131296908 0.0718 1.0327 3.2239 0.8679 3 1WCM158_X1_1 12 131306314 133810874 −0.1188 0.5888 2.1563 0.8516 2 1WCM158_X1_1 13 19600159 39550828 −0.1422 0.5282 1.7404 1.1439 2 1WCM158_X1_1 13 39550924 102051466 −0.2997 0.0728 1.959 0.1446 2 0WCM158_X1_1 13 102105212 115089411 −0.169 0.457 1.5951 1.1503 2 1WCM158_X1_1 14 19377719 20389264 −0.1192 0.5879 NA NA NA NA WCM158_X1_114 20389476 39650473 −0.0883 0.6654 3.0715 0.1006 3 0 WCM158_X1_1 1439650733 107283063 0.027 0.9352 3.0075 0.8168 3 1 WCM158_X1_1 1520170150 102517667 −0.1245 0.5742 1.9743 1.0034 2 1 WCM158_X1_1 16 66953135678 −0.2719 0.1605 NA NA NA NA WCM158_X1_1 16 136772 46655205 −0.27420.1532 1.1499 1.0741 1 1 WCM158_X1_1 16 46660579 69660315 −0.0829 0.67861.7501 1.4511 2 1 WCM158_X1_1 16 69678710 70508797 −0.2662 0.178 NA NANA NA WCM158_X1_1 16 70509327 90233627 −0.2744 0.1528 2.1108 0.1127 2 0WCM158_X1_1 17 131595 21191346 −0.2996 0.0731 2.0709 0.033 2 0WCM158_X1_1 17 21194843 81083455 0.0783 1.0466 2.1184 2.0128 2 2WCM158_X1_1 18 49000 78005210 0.0366 0.9563 3.0173 0.8634 3 1WCM158_X1_1 19 281503 5623236 −0.1048 0.6242 2.0954 0.9873 2 1WCM158_X1_1 19 5626460 19768190 0.0664 1.0213 2.0559 2.0035 2 2WCM158_X1_1 19 19770501 33414392 −0.058 0.739 2.0893 1.2488 2 1WCM158_X1_1 19 33417117 59083929 0.0545 0.9955 2.9587 1.0288 3 1WCM158_X1_1 2 41609 32419023 0.0386 0.9608 2.0362 1.8565 2 2 WCM158_X1_12 32422422 58311262 −0.3288 −0.023 1.8998 0.0685 2 0 WCM158_X1_1 258313555 89442316 0.0494 0.9844 2.0043 1.9526 2 2 WCM158_X1_1 2 89475873115822349 −0.1094 0.6128 2.2012 0.8571 2 1 WCM158_X1_1 2 115919825141474380 −0.5362 −0.8893 1.1145 −0.0348 1 0 WCM158_X1_1 2 141526813242946616 −0.1373 0.5412 1.9249 0.9854 2 1 WCM158_X1_1 20 68351 62904932−0.0664 0.7188 2.2546 1.037 2 1 WCM158_X1_1 21 9826207 48084282 0.06651.0214 2.0823 1.9776 2 2 WCM158_X1_1 22 16287495 32554985 −0.3018 0.06612.0271 0.0666 2 0 WCM158_X1_1 22 32579559 51064080 −0.1158 0.5964 2.0081.0159 2 1 WCM158_X1_1 22 51064485 51215157 −0.2745 0.1524 NA NA NA NAWCM158_X1_1 3 239349 431068 0.1935 1.2817 NA NA NA NA WCM158_X1_1 3432418 13679203 0.2929 1.4706 3.629 1.9138 4 2 WCM158_X1_1 3 1367933547614274 0.278 1.443 3.6838 1.7539 4 2 WCM158_X1_1 3 47618447 560262160.2016 1.2976 2.6307 2.2857 3 2 WCM158_X1_1 3 56041300 89528635 0.06231.0124 2.6569 1.3778 3 1 WCM158_X1_1 3 93595943 97454773 0.3973 1.6573NA NA NA NA WCM158_X1_1 3 97464222 148881712 0.4098 1.679 5.4715 0.93255 1 WCM158_X1_1 3 148883833 197896711 0.2892 1.4637 5.36 0.1564 5 0WCM158_X1_1 4 59390 118006371 −0.1045 0.625 2.0654 1.019 2 1 WCM158_X1_14 118006445 138442774 −0.3287 −0.0226 2.003 −0.0341 2 0 WCM158_X1_1 4138449683 190426502 −0.1617 0.4766 1.9315 0.8513 2 1 WCM158_X1_1 5140636 64748682 −0.1605 0.4799 1.8233 0.9659 2 1 WCM158_X1_1 5 6475616482360910 −1.00E−04 0.8741 2.6828 0.983 3 1 WCM158_X1_1 5 8237314296519257 −0.181 0.4244 2.7423 −0.0583 3 0 WCM158_X1_1 5 98109791107197473 −0.8747 NA NA NA NA NA WCM158_X1_1 5 107216644 112102993−0.1836 0.4173 2.5938 0.077 3 0 WCM158_X1_1 5 112116552 180687769 0.02610.9332 2.9405 0.8785 3 1 WCM158_X1_1 6 203699 64390043 −0.0064 0.85982.7108 0.9188 3 1 WCM158_X1_1 6 64394035 70745815 −0.2084 0.348 NA NA NANA WCM158_X1_1 6 70769669 96997436 −0.4305 −0.3991 1.1479 0.3688 1 0WCM158_X1_1 6 96997629 170893450 −0.1597 0.4819 1.8666 0.9266 2 1WCM158_X1_1 7 193222 158937046 0.2707 1.4294 2.7487 2.6381 3 3WCM158_X1_1 8 190900 607779 −0.5608 −1.0252 NA NA NA NA WCM158_X1_1 8608034 12888899 −0.5406 −0.9128 0.9093 0.153 1 0 WCM158_X1_1 8 1294335635425672 −0.3178 0.0136 1.9087 0.1102 2 0 WCM158_X1_1 8 3545311251664666 0.2309 1.3542 5.0845 0.0285 5 0 WCM158_X1_1 8 51705264 71520327−0.1354 0.546 2.8029 0.1172 3 0 WCM158_X1_1 8 71550105 146279489 0.2111.3159 5.0457 −0.0666 5 0 WCM158_X1_1 9 17074 23705016 −0.2068 0.35251.4104 1.1432 1 1 WCM158_X1_1 9 23731032 140852095 0.0566 1.0001 2.93611.0641 3 1 WCM158_X1_1 9 140865989 141111414 −0.0524 0.7526 NA NA NA NAWCM158_X1_1 X 2700151 46539182 −0.0855 0.6722 NA NA NA NA WCM158_X1_1 X46541841 52681330 −0.3961 −0.2638 NA NA NA NA WCM158_X1_1 X 52825534136113442 0.0154 0.9093 NA NA NA NA WCM158_X1_1 X 136113784 140969584−0.788 −3.6492 NA NA NA NA WCM158_X1_1 X 140982567 154509348 0.06391.0157 NA NA NA NA WCM15_Z1_1 1 808999 10408784 0.0876 0.0144 1.01971.0004 1 1 WCM15_Z1_1 1 10412700 12780904 −0.7759 −0.9257 1.06 −0.0072 10 WCM15_Z1_1 1 12785303 249212579 0.087 0.0139 1.0097 1.0097 1 1WCM15_Z1_1 10 225952 44876365 0.0595 −0.0154 0.9989 0.9799 1 1WCM15_Z1_1 10 45406998 62149194 −0.8055 −0.959 1.0314 −0.0025 1 0WCM15_Z1_1 10 62539896 74774057 0.0981 0.0256 1.0244 1.0114 1 1WCM15_Z1_1 10 74776587 76603080 −0.815 −0.9696 1.0173 0.004 1 0WCM15_Z1_1 10 76603125 88213604 0.0656 −0.0089 1.0203 0.9674 1 1WCM15_Z1_1 10 88218761 88696746 −0.7971 −0.9496 NA NA NA NA WCM15_Z1_110 88702220 90774134 −3.5124 −5.3373 NA NA NA NA WCM15_Z1_1 10 9096639395279565 −0.7851 −0.9361 1.0634 −0.0181 1 0 WCM15_Z1_1 10 95287873105093694 0.087 0.0138 1.0204 0.9989 1 1 WCM15_Z1_1 10 105104833106163525 −0.8342 −0.9913 1.0047 0.0014 1 0 WCM15_Z1_1 10 106166524135373678 0.0371 −0.0393 0.9731 0.9731 1 1 WCM15_Z1_1 11 193096134257436 0.0624 −0.0123 0.9957 0.9873 1 1 WCM15_Z1_1 12 247582 11548375−0.8181 −0.9731 1.0299 −0.0111 1 0 WCM15_Z1_1 12 11803048 12871051−3.5811 −5.6001 NA NA NA NA WCM15_Z1_1 12 12917552 14019034 −0.8244−0.9802 NA NA NA NA WCM15_Z1_1 12 14577059 15073853 0.801 0.763 NA NA NANA WCM15_Z1_1 12 15087898 133779249 0.0834 0.01 1.0091 1.0048 1 1WCM15_Z1_1 13 19747959 21751210 −0.3668 −0.4741 NA NA NA NA WCM15_Z1_113 21751271 48835337 0.6114 0.5658 2.9625 −0.0021 3 0 WCM15_Z1_1 1348878001 115089411 −0.8513 −1.0106 0.9932 −5.00E−04  1 0 WCM15_Z1_1 1420215851 107283088 0.634 0.5894 1.9955 1.0137 2 1 WCM15_Z1_1 15 2017013324921462 −0.0323 −0.1133 1.465 0.3839 1 0 WCM15_Z1_1 15 2492177128525361 −0.0531 −0.1356 0.9308 0.8899 1 1 WCM15_Z1_1 15 2890081959813441 −0.3119 −0.4145 0.9725 0.528 1 1 WCM15_Z1_1 15 59910425102359167 0.0802 0.0066 1.496 0.5131 1 1 WCM15_Z1_1 16 97610 67335734−0.8077 −0.9615 1.0274 −3.00E−04  1 0 WCM15_Z1_1 16 67337200 679436420.4085 0.3534 NA NA NA NA WCM15_Z1_1 16 67961447 90161760 −0.8129−0.9673 1.0287 −0.0057 1 0 WCM15_Z1_1 17 131595 16097787 0.0345 −0.0421.9443 −0.0017 2 0 WCM15_Z1_1 17 16120623 21188298 −0.8376 −0.99511.0044 −0.0011 1 0 WCM15_Z1_1 17 21201719 81052325 0.0695 −0.0048 1.0020.9914 1 1 WCM15_Z1_1 18 47646 78005197 −0.3082 −0.4104 1.5115 −0.0067 20 WCM15_Z1_1 19 281565 11436181 0.0194 −0.0582 0.9646 0.9564 1 1WCM15_Z1_1 19 11446316 14294396 −0.8891 −1.0533 0.9588 0.0049 1 0WCM15_Z1_1 19 14492263 15807807 0.0209 −0.0566 0.9728 0.9503 1 1WCM15_Z1_1 19 15838925 59082752 0.5914 0.5449 1.9371 0.9808 2 1WCM15_Z1_1 2 41583 61420113 −0.3003 −0.4019 0.9949 0.5189 1 1 WCM15_Z1_12 61430344 62132964 −0.8124 −0.9667 NA NA NA NA WCM15_Z1_1 2 62227997110373618 −0.3034 −0.4052 0.9893 0.5209 1 1 WCM15_Z1_1 2 110881513112786476 −1.5668 −1.8504 NA NA NA NA WCM15_Z1_1 2 112817600 174232341−0.2883 −0.3889 1.0062 0.5213 1 1 WCM15_Z1_1 2 174774863 176046152−1.5922 −1.8817 NA NA NA NA WCM15_Z1_1 2 176794779 242815461 −0.2973−0.3985 1.0004 0.5168 1 1 WCM15_Z1_1 20 68336 26188809 −0.6045 −0.73491.2037 −0.002 1 0 WCM15_Z1_1 20 29845559 62904835 0.2149 0.1495 1.13141.0869 1 1 WCM15_Z1_1 21 10862667 48084270 0.0508 −0.0247 0.9883 0.97781 1 WCM15_Z1_1 22 17072636 38485064 −0.8198 −0.9751 1.0183 −9.00E−04  10 WCM15_Z1_1 22 38485716 38710157 −3.4227 −5.0392 NA NA NA NA WCM15_Z1_122 38822894 43582988 −0.8218 −0.9773 1.0271 −0.0112 1 0 WCM15_Z1_1 2243600006 44131712 −3.6181 −5.7582 NA NA NA NA WCM15_Z1_1 22 4415164651216336 −0.8171 −0.972 1.0243 −0.0047 1 0 WCM15_Z1_1 3 367645 1977654320.0902 0.0173 1.012 1.012 1 1 WCM15_Z1_1 4 53340 27162532 −0.8554−1.0151 0.9919 −0.0024 1 0 WCM15_Z1_1 4 30723155 77134535 −0.3115 −0.4140.99 0.5111 1 1 WCM15_Z1_1 4 77228029 85504535 −1.615 −1.9099 0.5472−0.015 1 0 WCM15_Z1_1 4 85525527 189068520 −0.2997 −0.4012 0.9929 0.52161 1 WCM15_Z1_1 5 140663 50689286 0.4385 0.3849 1.4661 1.1456 1 1WCM15_Z1_1 5 52096290 148207663 −0.2829 −0.383 1.5394 −0.0057 2 0WCM15_Z1_1 5 148384455 149265875 0.8371 0.8005 1.9601 1.5232 2 2WCM15_Z1_1 5 149274826 149932950 0.4177 0.3631 1.5305 1.0418 2 1WCM15_Z1_1 5 150027818 153857582 0.8753 0.84 2.0347 1.5453 2 2WCM15_Z1_1 5 154092540 180687824 0.4395 0.386 1.4781 1.1354 1 1WCM15_Z1_1 6 292575 18465260 0.0785 0.0048 1.0194 0.9874 1 1 WCM15_Z1_16 18572160 28472253 −0.8603 −1.0207 0.9922 −0.0065 1 0 WCM15_Z1_1 628473566 170892853 0.0791 0.0054 1.008 0.9995 1 1 WCM15_Z1_1 7 19368716918167 −0.7718 −0.9211 1.0626 −0.0064 1 0 WCM15_Z1_1 7 1733890018633661 1.7016 1.6886 NA NA NA NA WCM15_Z1_1 7 18669158 45614757 0.0970.0245 1.0312 1.0031 1 1 WCM15_Z1_1 7 45632498 131982831 −0.0136 −0.09341.0014 0.8733 1 1 WCM15_Z1_1 7 132070054 158937481 0.5529 0.5047 1.96740.8702 2 1 WCM15_Z1_1 8 190890 681206 −0.0167 −0.0967 NA NA NA NAWCM15_Z1_1 8 1496890 31498232 −0.8319 −0.9887 1.0149 −0.0071 1 0WCM15_Z1_1 8 32406274 146279472 0.057 −0.0181 0.9875 0.9875 1 1WCM15_Z1_1 9 214625 66517198 −0.2877 −0.3882 1.0365 0.4917 1 0WCM15_Z1_1 9 71144570 78547330 −1.6631 −1.9698 0.502 0.0086 1 0WCM15_Z1_1 9 78601149 141016415 −0.2946 −0.3956 1.0189 0.5014 1 1WCM15_Z1_1 X 2700119 25033756 1.3114 1.2895 NA NA NA NA WCM15_Z1_1 X26157133 154507335 0.5804 0.5334 NA NA NA NA WCM160 1 14907 62444854−0.0242 −0.1584 0.896 0.896 1 1 WCM160 1 62445467 117618067 −0.1379−1.2173 0.4301 0.4301 0 0 WCM160 1 117618402 145475385 −0.0494 −0.34071.0131 0.5662 1 1 WCM160 1 145487351 156670737 0.2857 1.2443 2.369 2.3692 2 WCM160 1 156670822 228456529 0.096 0.5162 1.4302 1.4302 1 1 WCM160 1228459663 228601638 0.3421 1.4181 2.6724 2.6724 3 3 WCM160 1 228602501249214028 −0.0651 −0.4651 0.7244 0.7244 1 1 WCM160 10 226060 135477933−0.0362 −0.2429 0.8451 0.8451 1 1 WCM160 11 193112 61717854 0.07480.4143 1.3326 1.3326 1 1 WCM160 11 61719237 65836130 −0.0813 −0.60510.6574 0.6574 1 1 WCM160 11 65961017 107526694 0.1363 0.6954 1.61941.6194 2 2 WCM160 11 107535902 126310358 −0.0993 −0.7749 0.6544 0.5144 11 WCM160 11 126314948 134605906 0.1214 0.6309 1.5486 1.5486 2 2 WCM16012 148468 133810703 −0.0231 −0.1508 0.9008 0.9008 1 1 WCM160 13 19041937115089411 −0.0809 −0.6017 0.659 0.659 1 1 WCM160 14 19110188 107283269−0.0135 −0.0868 0.9416 0.9416 1 1 WCM160 15 20083889 35235505 0.10470.5563 1.5444 1.3965 2 1 WCM160 15 35236651 102291971 −0.0347 −0.23160.8517 0.8517 1 1 WCM160 15 102292673 102514248 −0.0399 −0.2695 NA NA NANA WCM160 16 66868 304565 0.0841 0.4594 NA NA NA NA WCM160 16 30466119234465 0.1958 0.9324 1.937 1.8798 2 2 WCM160 16 19236063 289502230.423 1.6459 3.7243 2.5345 4 3 WCM160 16 28962488 30046763 0.2265 1.04444.2343 −0.1093 4 0 WCM160 16 30064826 90260461 −0.0846 −0.6349 0.70880.5792 1 1 WCM160 17 131595 10097546 −0.1787 −1.879 0.4707 0.0731 0 0WCM160 17 10204269 29704153 0.0993 0.5315 1.4455 1.4455 1 1 WCM160 1729704421 37902376 0.423 1.6459 3.9339 2.325 4 2 WCM160 17 3790306381187883 −0.0245 −0.1607 0.8946 0.8946 1 1 WCM160 18 47666 78005150−0.0108 −0.0686 0.9535 0.9535 1 1 WCM160 19 104935 59093645 −0.0483−0.332 0.7944 0.7944 1 1 WCM160 2 41595 275178 0.0235 0.1411 NA NA NA NAWCM160 2 276942 202150042 −0.0507 −0.3509 0.8082 0.76 1 1 WCM160 2202151148 243037103 0.0593 0.3359 1.2622 1.2622 1 1 WCM160 20 6831962934618 0.104 0.5531 1.4672 1.4672 1 1 WCM160 21 9590356 48084189−0.1532 −1.4333 0.3703 0.3703 0 0 WCM160 22 16159060 51223730  3.00E−040.0021 1.0014 1.0014 1 1 WCM160 3 239390 197896638 −0.0271 −0.17850.8836 0.8836 1 1 WCM160 4 53345 49601579 −0.0328 −0.2182 0.8596 0.85961 1 WCM160 4 52729276 100851835 0.0941 0.5074 1.4348 1.4081 1 1 WCM160 4100867759 101045932 −1.4365 NA NA NA NA NA WCM160 4 101046788 1842415500.0556 0.3167 1.278 1.213 1 1 WCM160 4 184241811 190878479 −0.008−0.0505 1.0091 0.9221 1 1 WCM160 5 90647 37057454 0.0524 0.3 1.23111.2311 1 1 WCM160 5 37058956 145562047 −0.066 −0.4732 0.7204 0.7204 1 1WCM160 5 145583278 180687854 0.0435 0.2526 1.1913 1.1913 1 1 WCM160 6203542 33545262 0.0329 0.1944 1.1442 1.1442 1 1 WCM160 6 3355345565016935 0.1392 0.7077 1.6332 1.6332 2 2 WCM160 6 65097346 170892883−0.0391 −0.264 0.8328 0.8328 1 1 WCM160 7 193205 158937158 0.0343 0.2021.1503 1.1503 1 1 WCM160 8 163470 38959498 −0.1024 −0.8064 0.5951 0.54851 1 WCM160 8 38961086 146279383 0.2277 1.0487 2.0687 2.0687 2 2 WCM160 914886 141107539 0.0753 0.4169 1.335 1.335 1 1 WCM160 X 2700189 658195670.0209 0.126 NA NA NA NA WCM160 X 65819850 67454319 2.481 4.8896 NA NANA NA WCM160 X 67494544 68383243 1.1119 3.0458 NA NA NA NA WCM160 X68394313 154493601 0.0326 0.1926 NA NA NA NA WCM160_X1_1 1 721450249212243 0.0021 NA NA NA NA NA WCM160_X1_1 10 255851 135440080 −0.0049NA NA NA NA NA WCM160_X1_1 11 193112 134856603 0.0096 NA NA NA NA NAWCM160_X1_1 12 148674 133810703 0.001 NA NA NA NA NA WCM160_X1_1 1319600475 115089411 −0.0188 NA NA NA NA NA WCM160_X1_1 14 20201693107283026 0.0059 NA NA NA NA NA WCM160_X1_1 15 20169971 102515282 6.00E−04 NA NA NA NA NA WCM160_X1_1 16 67604 90161743 0.0082 NA NA NANA NA WCM160_X1_1 17 131595 81083455 0.0148 NA NA NA NA NA WCM160_X1_118 49034 78005160 −0.0228 NA NA NA NA NA WCM160_X1_1 19 281430 590839530.0035 NA NA NA NA NA WCM160_X1_1 2 41613 242946604 −7.00E−04 NA NA NANA NA WCM160_X1_1 20 68375 62904835 0.0101 NA NA NA NA NA WCM160_X1_1 219826203 48084281 0.0072 NA NA NA NA NA WCM160_X1_1 22 16287454 512151300.0248 NA NA NA NA NA WCM160_X1_1 3 239350 197894713 0.0025 NA NA NA NANA WCM160_X1_1 4 59331 190426502 −0.0143 NA NA NA NA NA WCM160_X1_1 5140448 180687768 −0.0026 NA NA NA NA NA WCM160_X1_1 6 203615 170892697−0.0099 NA NA NA NA NA WCM160_X1_1 7 193451 158937022 −0.0098 NA NA NANA NA WCM160_X1_1 8 190906 146279472 −0.0101 NA NA NA NA NA WCM160_X1_19 17073 141111414 0.0042 NA NA NA NA NA WCM160_X1_1 X 2707694 154509348−0.0526 NA NA NA NA NA WCM160_Z7_1 1 721415 21585265 −0.1959 −0.60630.9825 0.3312 1 0 WCM160_Z7_1 1 21586773 62483618 −0.1094 −0.317 0.84530.7601 1 1 WCM160_Z7_1 1 62503653 145109583 −0.2269 −0.7211 0.759 0.45421 0 WCM160_Z7_1 1 145112485 145439923 0.0725 0.1882 NA NA NA NAWCM160_Z7_1 1 145440294 156641049 0.5097 1.1012 2.5956 1.6951 3 2WCM160_Z7_1 1 156641353 156815487 0.0846 0.2181 NA NA NA NA WCM160_Z7_11 156815892 180180665 0.0469 0.1235 1.6869 0.4919 2 0 WCM160_Z7_1 1180199714 223285646 0.2044 0.4971 1.4612 1.3615 1 1 WCM160_Z7_1 1223285946 229738236 0.0203 0.0541 1.104 0.9725 1 1 WCM160_Z7_1 1229738549 234586237 −0.2143 −0.6736 1.242 0.0119 1 0 WCM160_Z7_1 1234593444 249212111 −0.0554 −0.1549 0.9996 0.7967 1 1 WCM160_Z7_1 10255922 3167355 −0.1738 −0.5286 NA NA NA NA WCM160_Z7_1 10 317212158117891 −0.0776 −0.2202 0.9122 0.8047 1 1 WCM160_Z7_1 10 58118330101689378 0.0578 0.1512 1.1302 1.0908 1 1 WCM160_Z7_1 10 101689826106075786 −0.1185 −0.3458 0.8591 0.7147 1 1 WCM160_Z7_1 10 106113656135440086 −0.26 −0.8513 1.087 0.0216 1 0 WCM160_Z7_1 11 193112 651672380.0478 0.1257 1.1134 1.0687 1 1 WCM160_Z7_1 11 65168230 105481795 0.16910.4181 1.3696 1.3028 1 1 WCM160_Z7_1 11 105483133 107326440 0.09390.2409 NA NA NA NA WCM160_Z7_1 11 107328498 126162862 −0.2482 −0.8041.0961 0.0494 1 0 WCM160_Z7_1 11 126162885 134856489 0.0269 0.07161.1611 0.9408 1 1 WCM160_Z7_1 12 148675 133810703 −0.0903 −0.2585 1.17360.4983 1 0 WCM160_Z7_1 13 19600475 19997282 −0.213 −0.669 NA NA NA NAWCM160_Z7_1 13 20012234 32676149 0.0378 0.1 1.4408 0.7028 1 1WCM160_Z7_1 13 32691547 115089411 −0.2384 −0.7652 0.6365 0.5403 1 1WCM160_Z7_1 14 20201708 20470903 −0.1446 −0.4301 1.5955 −0.1111 2 0WCM160_Z7_1 14 20471089 38679473 0.05 0.1314 1.1038 1.087 1 1WCM160_Z7_1 14 38679656 107283027 −0.0919 −0.2634 1.107 0.5593 1 1WCM160_Z7_1 15 20169972 20876515 0.2536 0.6036 2.2348 0.8041 2 1WCM160_Z7_1 15 21145647 37100525 0.1579 0.3924 1.7347 0.8904 2 1WCM160_Z7_1 15 37101104 102515271 −0.0895 −0.2561 1.1142 0.5605 1 1WCM160_Z7_1 16 67604 18847528 0.3002 0.7005 2.1542 1.096 2 1 WCM160_Z7_116 18847837 30569350 0.5463 1.1662 3.5545 0.9338 4 1 WCM160_Z7_1 1630581403 30719006 0.1591 0.3951 NA NA NA NA WCM160_Z7_1 16 3072105561687709 −0.0482 −0.134 1.2276 0.595 1 1 WCM160_Z7_1 16 6168797990108923 −0.2553 −0.8322 1.1323 −0.009 1 0 WCM160_Z7_1 16 9010970290161547 −0.0985 −0.2835 NA NA NA NA WCM160_Z7_1 17 131595 10101706−0.2669 −0.8798 1.0398 0.047 1 0 WCM160_Z7_1 17 10204987 21318882 0.08650.2227 1.2014 1.1325 1 1 WCM160_Z7_1 17 21318996 29761098 0.2187 0.52841.7474 1.1372 2 1 WCM160_Z7_1 17 29844704 37899218 0.5951 1.2509 3.73931.0203 4 1 WCM160_Z7_1 17 37899479 81083419 −0.1044 −0.3018 1.14560.4769 1 0 WCM160_Z7_1 18 49034 78005206 −0.119 −0.3474 0.9428 0.6292 11 WCM160_Z7_1 19 281507 59083988 −0.1119 −0.3249 1.131 0.4657 1 0WCM160_Z7_1 2 41612 1457570 −0.0159 −0.0435 NA NA NA NA WCM160_Z7_1 21459965 26534054 −0.0831 −0.2366 1.6372 0.0604 2 0 WCM160_Z7_1 226534322 26534345 −2.4875 NA NA NA NA NA WCM160_Z7_1 2 26534813 71886073−0.0755 −0.214 1.7136 0.0106 2 0 WCM160_Z7_1 2 71887715 89890579 −0.2628−0.8627 1.0951 0.0048 1 0 WCM160_Z7_1 2 89986379 90139116 0.5343 1.145NA NA NA NA WCM160_Z7_1 2 90139370 202260154 −0.0694 −0.196 1.09960.6463 1 1 WCM160_Z7_1 2 202262942 234449316 0.0744 0.1928 1.6809 0.60522 1 WCM160_Z7_1 2 234450931 242946607 −0.1187 −0.3466 0.8288 0.7441 1 1WCM160_Z7_1 20 68396 55012318 0.0357 0.0946 1.0872 1.0484 1 1WCM160_Z7_1 20 55012582 62904835 0.3256 0.7521 2.0669 1.3015 2 1WCM160_Z7_1 21 9826205 48084282 −0.2764 −0.9194 0.5578 0.4997 1 0WCM160_Z7_1 22 16287431 46486972 −0.1084 −0.3142 1.0726 0.5361 1 1WCM160_Z7_1 22 46493816 51215153 −0.4762 −2.0579 0.485 −0.0046 0 0WCM160_Z7_1 3 239531 197894713 −0.0809 −0.2301 1.1183 0.5868 1 1WCM160_Z7_1 4 59334 47034626 −0.0885 −0.2528 1.1062 0.5723 1 1WCM160_Z7_1 4 47034738 57676321 0.1494 0.3728 1.5227 1.0671 2 1WCM160_Z7_1 4 57686706 75107314 −0.0872 −0.2489 1.6608 0.0223 2 0WCM160_Z7_1 4 75147195 190426502 0.0993 0.2541 1.6732 0.7119 2 1WCM160_Z7_1 5 140477 162910046 −0.0762 −0.216 1.1352 0.5866 1 1WCM160_Z7_1 5 162930418 180687768 0.178 0.4382 1.4405 1.2693 1 1WCM160_Z7_1 6 203624 398901 −0.1096 −0.3177 NA NA NA NA WCM160_Z7_1 6401492 64791847 0.1827 0.4487 1.6869 1.0427 2 1 WCM160_Z7_1 6 64940499170892612 −0.0851 −0.2428 1.1534 0.5368 1 1 WCM160_Z7_1 7 193254158937227 −0.1088 −0.3152 0.8288 0.7787 1 1 WCM160_Z7_1 8 19090739550165 −0.3175 −1.1014 0.7675 0.1646 1 0 WCM160_Z7_1 8 39581427146279498 0.3163 0.7333 2.2144 1.1106 2 1 WCM160_Z7_1 9 17107 141111414−0.0069 −0.0187 1.014 0.9602 1 1 WCM160_Z7_1 X 2707709 65474878 0.00380.0101 NA NA NA NA WCM160_Z7_1 X 65476180 68382719 1.7329 2.8641 NA NANA NA WCM160_Z7_1 X 68382969 154509348 0.0144 0.0387 NA NA NA NA WCM1611 14930 35470728 −0.0226 −0.0169 0.9884 0.9884 1 1 WCM161 1 3547261151323474 −0.1413 −0.2612 0.8344 0.8344 1 1 WCM161 1 51425515 111397084−0.3116 −0.6563 0.7844 0.4845 1 0 WCM161 1 111397401 118426295 −0.207−0.4065 0.7544 0.7544 1 1 WCM161 1 118429221 167367336 0.1167 0.24611.186 1.186 1 1 WCM161 1 167368543 178269220 −0.2422 −0.4877 1.21030.216 1 0 WCM161 1 178271298 249214028 0.1348 0.2787 1.2131 1.2131 1 1WCM161 10 225958 459820 −0.0949 −0.1632 NA NA NA NA WCM161 10 46008211312806 −0.2288 −0.4565 1.1224 0.3351 1 0 WCM161 10 11317093 158853060.1103 0.2343 1.2234 1.1293 1 1 WCM161 10 15889863 21807083 −0.3096−0.6512 1.1463 0.1271 1 0 WCM161 10 21807340 28599927 −0.0859 −0.14460.9699 0.8393 1 1 WCM161 10 28821811 29844067 −0.4682 −1.088 0.93840.0024 1 0 WCM161 10 29852240 38622117 −0.1351 −0.2478 0.8963 0.7881 1 1WCM161 10 38633714 38679824 −0.3068 −0.6443 NA NA NA NA WCM161 1038680963 135477897 0.0199 0.0657 1.0466 1.0466 1 1 WCM161 11 1930961269642 0.12 0.2521 1.7611 0.6207 2 1 WCM161 11 1270348 26725462 0.06820.1569 1.7231 0.5067 2 1 WCM161 11 26730894 65234014 0.0728 0.16561.6006 0.6427 2 1 WCM161 11 65265357 65293819 −1.2204 NA NA NA NA NAWCM161 11 65294444 94209605 0.0865 0.1909 1.5556 0.7273 2 1 WCM161 1194211871 134241094 −0.1056 −0.1854 0.8978 0.861 1 1 WCM161 11 134241320134605849 0.0102 0.0472 NA NA NA NA WCM161 12 148485 11547405 −0.1797−0.3451 0.789 0.7855 1 1 WCM161 12 11548341 20602432 −0.4754 −1.11010.8179 0.1087 1 0 WCM161 12 20704634 21317791 −0.0257 −0.0231 1.03660.9316 1 1 WCM161 12 21319526 30906509 −0.4547 −1.0474 0.7829 0.1848 1 0WCM161 12 31106915 100043645 −0.0064 0.0148 1.0103 1.0103 1 1 WCM161 12100048854 133810880 −0.1011 −0.176 0.8852 0.8852 1 1 WCM161 13 1904200422141055 0.7439 1.2357 3.4989 1.211 3 1 WCM161 13 22178125 37453797−0.3637 −0.7909 1.0073 0.1487 1 0 WCM161 13 37524255 40362491 0.64931.1007 3.2595 1.0298 3 1 WCM161 13 40783682 42897300 −0.4059 −0.90630.9101 0.157 1 0 WCM161 13 43148586 46594713 0.5942 1.0202 3.0415 1.0153 1 WCM161 13 46616324 58299838 −0.5909 −1.4992 0.5628 0.1447 1 0 WCM16113 58300293 95271496 −0.1654 −0.3135 0.8082 0.8012 1 1 WCM161 1395271797 101315270 −0.5872 −1.4856 0.5218 0.1924 1 0 WCM161 13 101315464115089411 0.0505 0.1238 1.2967 0.8825 1 1 WCM161 14 19110348 517227520.1292 0.2686 1.2047 1.2047 1 1 WCM161 14 51956133 82000125 −0.118−0.2115 0.9239 0.8034 1 1 WCM161 14 82127872 107283255 0.1242 0.25951.1971 1.1971 1 1 WCM161 15 20083992 78274014 −0.0735 −0.1191 1.21430.6272 1 1 WCM161 15 78277960 102506273 0.0489 0.1209 1.0956 1.0792 1 1WCM161 16 66905 72816877 −0.0107 0.0064 1.0045 1.0045 1 1 WCM161 1672817159 90260461 −0.441 −1.0067 0.8229 0.1724 1 0 WCM161 17 13159521176028 −0.2256 −0.449 1.3726 0.0925 1 0 WCM161 17 21201719 777698370.1906 0.3771 1.2988 1.2988 1 1 WCM161 17 77770234 80858575 0.0305 0.0861.381 0.7419 1 1 WCM161 17 80861313 81187946 0.2563 0.4895 NA NA NA NAWCM161 18 47692 14157278 0.3543 0.651 1.8309 1.3095 2 1 WCM161 1814169508 44057760 0.1848 0.367 1.3167 1.2627 1 1 WCM161 18 4406363946388898 0.3263 0.6056 1.6358 1.4074 2 1 WCM161 18 46446442 78005215−0.0158 −0.0035 0.9976 0.9976 1 1 WCM161 19 105080 9251120 −0.1507−0.2815 0.8388 0.8067 1 1 WCM161 19 9266682 34583879 0.0759 0.17131.1449 1.1073 1 1 WCM161 19 34583985 59093696 −0.2276 −0.4537 0.73020.7302 1 1 WCM161 2 41463 206628638 −0.086 −0.1447 0.9046 0.9046 1 1WCM161 2 206630337 240500567 −0.1822 −0.3506 0.7843 0.7843 1 1 WCM161 2240504813 243037116 −0.105 −0.1841 0.8894 0.871 1 1 WCM161 20 6839762934592 0.1761 0.3518 1.2762 1.2762 1 1 WCM161 21 9590301 15310168−0.0643 −0.1003 1.2586 0.6071 1 1 WCM161 21 15310356 22840930 −0.0957−0.1647 1.6129 0.1713 2 0 WCM161 21 22841154 39754989 −0.2411 −0.48531.0678 0.3609 1 0 WCM161 21 39755310 42866347 0.1164 0.2455 2.03320.3377 2 0 WCM161 21 42866514 48084114 −0.136 −0.2498 1.2933 0.3888 1 0WCM161 22 16159046 38531080 −0.0539 −0.0792 1.2441 0.649 1 1 WCM161 2238536000 51045433 −0.1827 −0.3518 0.8377 0.7295 1 1 WCM161 22 5104805951223730 −0.1369 −0.2517 1.0434 0.6364 1 1 WCM161 3 239339 49457771−0.0814 −0.1353 1.266 0.555 1 1 WCM161 3 49457846 197445074 −0.023−0.0177 0.9878 0.9878 1 1 WCM161 3 197476474 197896798 −0.2063 −0.4049NA NA NA NA WCM161 4 53397 46929505 −0.0391 −0.0496 1.1628 0.7697 1 1WCM161 4 46929587 61529532 0.1588 0.3214 1.2495 1.2495 1 1 WCM161 461529897 77305346 0.405 0.7319 2.1012 1.2204 2 1 WCM161 4 7730557289591376 0.1641 0.3308 1.3486 1.1667 1 1 WCM161 4 89597416 1196130450.0189 0.0638 1.0452 1.0452 1 1 WCM161 4 119615699 128584736 0.25770.492 1.8183 0.9945 2 1 WCM161 4 128590255 139988840 −0.016 −0.00391.0404 0.9542 1 1 WCM161 4 139992984 177095753 0.2095 0.4099 1.63991.0172 2 1 WCM161 4 177098348 190904482 −0.1534 −0.2873 0.8444 0.7945 11 WCM161 5 90647 180687773 −0.0057 0.0161 1.0113 1.0113 1 1 WCM161 6203475 70386431 −0.0924 −0.1581 1.0615 0.731 1 1 WCM161 6 70407434170892918 −0.2223 −0.4414 0.7364 0.7364 1 1 WCM161 7 193185 483355330.174 0.3481 1.2729 1.2729 1 1 WCM161 7 48336844 80088200 −0.1832−0.3529 1.2974 0.2686 1 0 WCM161 7 80091509 104485901 0.162 0.327 1.4561.0528 1 1 WCM161 7 104546608 158937158 −0.1643 −0.3111 1.481 0.1311 1 0WCM161 8 163457 32621932 −0.4452 −1.0192 0.8278 0.1589 1 0 WCM161 833230203 41575226 0.7931 1.3046 4.0586 0.8816 4 1 WCM161 8 4157563785249809 0.6851 1.1522 3.445 1.0002 3 1 WCM161 8 85272976 1289598180.8493 1.382 4.1616 1.0511 4 1 WCM161 8 128960272 145678720 1.0767 1.6854.915 1.5156 5 2 WCM161 8 145689642 146279527 0.8721 1.4131 NA NA NA NAWCM161 9 14857 141107515 0.1939 0.3829 1.304 1.304 1 1 WCM161 X 27001477870115 −0.2311 −0.4619 NA NA NA NA WCM161 X 7880072 9935585 0.90881.4628 NA NA NA NA WCM161 X 9935807 14937969 0.1656 0.3334 NA NA NA NAWCM161 X 14938390 64754607 0.4917 0.8664 NA NA NA NA WCM161 X 6488774667518904 1.4727 2.1809 NA NA NA NA WCM161 X 67652875 67942444 0.30030.5629 NA NA NA NA WCM161 X 67943988 154509348 0.1644 0.3313 NA NA NA NAWCM161_Z1_1 1 69640 40363562 −0.258 0.5253 1.9011 0.9772 2 1 WCM161_Z1_11 40366619 111217266 −0.7153 −0.0698 1.9008 0.0047 2 0 WCM161_Z1_1 1111434052 145209388 −0.3028 0.4693 1.9139 0.855 2 1 WCM161_Z1_1 1145281656 167358840 0.3399 1.238 2.8411 1.8763 3 2 WCM161_Z1_1 1167365520 171765830 −0.7456 −0.1114 1.8911 −0.0398 2 0 WCM161_Z1_1 1171765886 174992477 −0.2728 0.5068 1.9278 0.9141 2 1 WCM161_Z1_1 1175037040 178252706 −0.7414 −0.1056 1.8888 −0.0299 2 0 WCM161_Z1_1 1178269164 249212557 0.0454 0.8939 1.8582 1.8582 2 2 WCM161_Z1_1 10225979 5141556 −0.2997 0.4732 NA NA NA NA WCM161_Z1_1 10 5144319 9281413−0.6732 −0.0125 1.9581 0.0246 2 0 WCM161_Z1_1 10 9449213 15902209−0.0094 0.8286 1.8143 1.7377 2 2 WCM161_Z1_1 10 16526423 21461323−0.7472 −0.1136 1.8542 −0.0057 2 0 WCM161_Z1_1 10 21784753 28438913−0.2655 0.516 1.5564 1.3035 2 1 WCM161_Z1_1 10 28491144 30306828 −0.7209−0.0775 1.8844 0.0111 2 0 WCM161_Z1_1 10 30315095 39147119 −0.28990.4855 1.88 0.9202 2 1 WCM161_Z1_1 10 42905606 44053435 0.0401 0.8877 NANA NA NA WCM161_Z1_1 10 44102500 75868764 0.0686 0.9215 1.9098 1.8784 22 WCM161_Z1_1 10 75871762 96454758 0.3331 1.2302 2.7506 1.9414 3 2WCM161_Z1_1 10 96466623 96609749 0.4115 1.32 NA NA NA NA WCM161_Z1_1 1096612495 135440090 0.0434 0.8915 2.7554 0.9549 3 1 WCM161_Z1_1 11 1931056412129 0.0595 0.9107 2.7501 1.0097 3 1 WCM161_Z1_1 11 6412744 70924740.3703 1.2728 2.6128 2.2198 3 2 WCM161_Z1_1 11 7110548 30034151 0.0390.8864 2.7483 0.9488 3 1 WCM161_Z1_1 11 30255185 96125013 0.3393 1.23732.8641 1.851 3 2 WCM161_Z1_1 11 96125317 113320759 0.0116 0.8537 1.90851.7056 2 2 WCM161_Z1_1 11 113558990 134856604 0.3578 1.2585 2.82051.9645 3 2 WCM161_Z1_1 12 148675 11903775 −0.709 −0.0611 0.9834 0.9336 11 WCM161_Z1_1 12 11905386 20522733 −1.3283 −0.9961 0.9448 0.0579 1 0WCM161_Z1_1 12 20523039 21325668 −0.2658 0.5156 NA NA NA NA WCM161_Z1_112 21327644 31079921 −1.3577 −1.0464 0.993 −0.0247 1 0 WCM161_Z1_1 1231106968 133810712 −0.2641 0.5177 1.8524 1.0109 2 1 WCM161_Z1_1 1319600515 22178262 1.4418 2.4503 NA NA NA NA WCM161_Z1_1 13 2224624326828877 −1.3502 −1.0335 0.9874 −0.0104 1 0 WCM161_Z1_1 13 2692326229608109 0.2477 1.1315 NA NA NA NA WCM161_Z1_1 13 29675095 30091439−1.0915 −0.6138 NA NA NA NA WCM161_Z1_1 13 30091835 32932032 0.26181.1479 NA NA NA NA WCM161_Z1_1 13 32936801 37453698 −1.1016 −0.62941.3159 −0.0231 1 0 WCM161_Z1_1 13 37524175 40362472 1.4669 2.477 NA NANA NA WCM161_Z1_1 13 41133727 42893286 −1.3827 −1.09 NA NA NA NAWCM161_Z1_1 13 43148655 46594663 1.5015 2.5138 NA NA NA NA WCM161_Z1_113 46616338 58299377 −1.3132 −0.9705 1.0902 −0.0696 1 0 WCM161_Z1_1 1360240961 61141739 −0.1884 0.6114 NA NA NA NA WCM161_Z1_1 13 6198560795257649 −0.7593 −0.1304 1.0806 0.7466 1 1 WCM161_Z1_1 13 95264604101308657 −1.3898 −1.1023 0.9315 0 1 0 WCM161_Z1_1 13 101315395115089411 −0.0989 0.7207 2.2998 0.9962 2 1 WCM161_Z1_1 14 1937771621699145 0.0602 0.9115 2.8588 0.9032 3 1 WCM161_Z1_1 14 2170217650998701 0.3361 1.2336 2.7597 1.9434 3 2 WCM161_Z1_1 14 5102700351721117 −0.3155 0.4534 NA NA NA NA WCM161_Z1_1 14 52156572 53619818−1.4031 −1.1258 NA NA NA NA WCM161_Z1_1 14 54416901 87379886 −0.27380.5056 2.8401 −7.00E−04  3 0 WCM161_Z1_1 14 87386660 93397704 0.29491.1862 2.4331 2.1179 2 2 WCM161_Z1_1 14 93398046 107283027 0.7369 1.68573.267 3.167 3 3 WCM161_Z1_1 15 20170113 102506284 −0.7111 −0.064 1.04560.8677 1 1 WCM161_Z1_1 16 67604 65025718 0.0842 0.94 1.9412 1.8958 2 2WCM161_Z1_1 16 65026863 72198696 −0.2318 0.5578 1.9115 1.0326 2 1WCM161_Z1_1 16 72821129 90233626 −0.6908 −0.0363 1.9501 2.00E−04 2 0WCM161_Z1_1 17 131595 21146674 −0.2721 0.5077 2.8332 0.0104 3 0WCM161_Z1_1 17 21147526 68172454 0.0719 0.9254 1.9262 1.8722 2 2WCM161_Z1_1 17 70117582 74729698 0.2879 1.178 2.3149 2.2104 2 2WCM161_Z1_1 17 74732285 74936537 −0.0792 0.7446 NA NA NA NA WCM161_Z1_117 74936836 81083398 −0.2325 0.5569 1.9723 0.9699 2 1 WCM161_Z1_1 1848339 31226226 0.2748 1.1629 2.5292 1.949 3 2 WCM161_Z1_1 18 3124168577891027 −0.0151 0.8217 2.6129 0.9221 3 1 WCM161_Z1_1 18 7789368378005224 0.0155 0.8583 NA NA NA NA WCM161_Z1_1 19 281498 19379441−0.2765 0.5023 1.922 0.9109 2 1 WCM161_Z1_1 19 19380538 59083953 −0.7116−0.0647 1.096 0.8162 1 1 WCM161_Z1_1 2 41609 242946597 −0.2834 0.49361.8619 0.9541 2 1 WCM161_Z1_1 20 68373 31238927 0.071 0.9244 1.92031.8753 2 2 WCM161_Z1_1 20 31291216 31998055 −0.2876 0.4884 NA NA NA NAWCM161_Z1_1 20 32000152 62904845 0.0878 0.9443 1.9447 1.9038 2 2WCM161_Z1_1 21 9826230 11097630 0.9211 1.8887 NA NA NA NA WCM161_Z1_1 2114745377 19169411 −0.7534 −0.1222 NA NA NA NA WCM161_Z1_1 21 1919056639822803 −0.2584 0.5247 1.8683 1.0091 2 1 WCM161_Z1_1 21 3994759342866299 0.8494 1.8101 6.0143 0.9989 6 1 WCM161_Z1_1 21 4287009548084211 −0.207 0.5884 1.9784 1.0287 2 1 WCM161_Z1_1 22 1706343119230365 0.4125 1.3211 2.9744 2.0226 3 2 WCM161_Z1_1 22 1934700524837301 −0.2247 0.5666 1.963 0.9991 2 1 WCM161_Z1_1 22 2483741324951586 0.645 1.5834 NA NA NA NA WCM161_Z1_1 22 24953769 26423602−0.2706 0.5096 1.9988 0.8486 2 1 WCM161_Z1_1 22 26565683 29678535 0.53621.4614 3.5548 1.9526 4 2 WCM161_Z1_1 22 29683020 36745230 −0.2432 0.54371.9099 1.0054 2 1 WCM161_Z1_1 22 36863959 37769219 0.8536 1.8146 5.23161.8037 5 2 WCM161_Z1_1 22 37769606 39239439 1.2786 2.2759 7.8923 1.794 82 WCM161_Z1_1 22 39262250 40814504 −0.2211 0.571 1.9191 1.052 2 1WCM161_Z1_1 22 40814636 50020539 −0.6682 −0.0057 1.12 0.8721 1 1WCM161_Z1_1 22 50168042 50708692 1.2712 2.268 8.6925 0.9406 9 1WCM161_Z1_1 22 50713811 51215138 −0.6901 −0.0354 1.0262 0.9253 1 1WCM161_Z1_1 3 239405 49343264 0.1707 1.0418 3.1361 0.9814 3 1WCM161_Z1_1 3 49348116 49462402 0.2081 1.0854 NA NA NA NA WCM161_Z1_1 349462825 99569326 0.408 1.3159 3.1629 1.8163 3 2 WCM161_Z1_1 3 99569595170218920 0.2237 1.1037 2.4165 1.8815 2 2 WCM161_Z1_1 3 170244462197259373 0.0243 0.8688 1.8566 1.7957 2 2 WCM161_Z1_1 3 197260370197410211 0.2666 1.1534 NA NA NA NA WCM161_Z1_1 3 197411090 1978947130.0636 0.9155 NA NA NA NA WCM161_Z1_1 4 59334 8129285 0.1787 1.05113.182 0.9622 3 1 WCM161_Z1_1 4 8206988 10566308 −0.2382 0.5498 1.60181.3259 2 1 WCM161_Z1_1 4 10567746 17782908 0.0924 0.9497 NA NA NA NAWCM161_Z1_1 4 17805295 49032896 −0.1946 0.6038 2.1128 0.9266 2 1WCM161_Z1_1 4 49034724 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1.0047 0.9799 1 1 WCM161_Z15_1 12 11803072 20523087 −1.4088−0.9561 1.0564 −0.0255 1 0 WCM161_Z15_1 12 20709602 21317791 −0.03940.4832 NA NA NA NA WCM161_Z15_1 12 21325705 30906565 −1.4256 −0.97420.9947 0.0233 1 0 WCM161_Z15_1 12 30948848 100169404 0.0317 0.55631.9649 0.976 2 1 WCM161_Z15_1 12 100173677 133810874 −0.5042 0.00181.0127 0.9898 1 1 WCM161_Z15_1 13 19600515 23238094 0.3953 0.929 NA NANA NA WCM161_Z15_1 13 23243302 37453532 −0.4911 0.0155 2.0201 0.0015 2 0WCM161_Z15_1 13 37453784 41133922 0.3925 0.926 NA NA NA NA WCM161_Z15_113 41134214 46563218 −0.4278 0.0814 1.8938 0.2223 2 0 WCM161_Z15_1 1346577368 58299420 −1.417 −0.9649 1.0198 0.0049 1 0 WCM161_Z15_1 1360240961 67802561 −0.6261 −0.1253 NA NA NA NA WCM161_Z15_1 13 7028178095271437 −0.012 0.5113 1.9168 0.9339 2 1 WCM161_Z15_1 13 95271757101316546 −1.4635 −1.0153 1.0049 −0.0154 1 0 WCM161_Z15_1 13 101318340115089411 0.0536 0.5788 1.9742 1.0131 2 1 WCM161_Z15_1 14 1937769751721141 0.438 0.9725 1.9623 1.9623 2 2 WCM161_Z15_1 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2 1 WCM161_Z15_1 2 205978257 242946607 −0.5199−0.0145 1.0034 0.9766 1 1 WCM161_Z15_1 20 68396 59091758 0.442 0.97661.9679 1.9679 2 2 WCM161_Z15_1 20 59139674 62904890 0.7431 1.2835 2.83052.0382 3 2 WCM161_Z15_1 21 9826235 48084226 −0.4612 0.0466 2.0644 0.00132 0 WCM161_Z15_1 22 17063440 18912678 −0.0909 0.4301 1.8501 0.8445 2 1WCM161_Z15_1 22 18913224 29537989 −0.4695 0.038 2.0524 0.0011 2 0WCM161_Z15_1 22 29563074 30188461 −1.3187 −0.8589 NA NA NA NAWCM161_Z15_1 22 30189467 51215157 −0.4896 0.017 2.0233 5.00E−04 2 0WCM161_Z15_1 3 239431 88205442 −0.5048 0.0012 1.0113 0.9904 1 1WCM161_Z15_1 3 88205677 115805400 0.0321 0.5567 1.9338 1.0081 2 1WCM161_Z15_1 3 116163765 133098806 −0.5164 −0.0108 1.0039 0.9811 1 1WCM161_Z15_1 3 133099060 197712716 0.0133 0.5373 1.9365 0.9661 2 1WCM161_Z15_1 3 197717503 197894719 −0.2125 0.3045 NA NA NA NAWCM161_Z15_1 4 59331 46067515 0.053 0.5782 1.9871 0.9988 2 1WCM161_Z15_1 4 46086060 46737146 −0.2663 0.2489 NA NA NA NA WCM161_Z15_14 46930289 71835721 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NA NA NA WCM161_Z15_1 X10035339 154509348 0.3033 0.8349 NA NA NA NA WCM161_Z6_1 1 6959039893161 −0.1329 0.9411 2.7681 1.0718 3 1 WCM161_Z6_1 1 39893768111738552 −0.3665 0.4945 2.8457 −0.0281 3 0 WCM161_Z6_1 1 111739863111862042 −0.052 1.0822 NA NA NA NA WCM161_Z6_1 1 111862872 120510847−0.1278 0.9501 2.6871 1.177 3 1 WCM161_Z6_1 1 120611425 167356420 0.10061.3338 2.8584 2.183 3 2 WCM161_Z6_1 1 167358837 178063703 −0.302 0.62452.8679 0.2155 3 0 WCM161_Z6_1 1 178252762 249212388 0.0766 1.2955 2.50212.4072 3 2 WCM161_Z6_1 10 225952 9281413 −0.4614 0.2911 2.3048 0.1423 20 WCM161_Z6_1 10 9449213 15902234 −0.1057 0.9892 2.0757 1.8945 2 2WCM161_Z6_1 10 16526479 38122001 −0.3842 0.4576 2.057 0.6894 2 1WCM161_Z6_1 10 38126632 75673879 −0.036 1.1094 2.1978 2.1173 2 2WCM161_Z6_1 10 75674588 75863605 −0.361 0.5058 NA NA NA NA WCM161_Z6_110 75864906 76781722 0.0556 1.2614 NA NA NA NA WCM161_Z6_1 10 7678482096698603 0.3335 1.6895 3.7499 2.7009 4 3 WCM161_Z6_1 10 96701711135043989 0.0857 1.31 3.8364 1.1224 4 1 WCM161_Z6_1 10 135044881135440068 −0.0707 1.0501 NA NA NA NA WCM161_Z6_1 11 193135 6341365−0.0473 1.0902 4.1505 0.1077 4 0 WCM161_Z6_1 11 6341675 7111497 0.17631.4528 4.1526 1.322 4 1 WCM161_Z6_1 11 7256013 28143692 −0.054 1.07884.2111 0.0136 4 0 WCM161_Z6_1 11 28219089 99786841 0.1612 1.4295 4.21991.167 4 1 WCM161_Z6_1 11 99827584 113320799 −0.2014 0.8168 2.6192 0.90373 1 WCM161_Z6_1 11 113558990 134856603 0.1959 1.4831 4.4706 1.1202 4 1WCM161_Z6_1 12 148644 12232263 −0.2587 0.7087 2.1986 1.0702 2 1WCM161_Z6_1 12 12232563 31079921 −0.5617 0.0575 2.0289 0.0523 2 0WCM161_Z6_1 12 31107026 133779852 −0.0502 1.0852 2.1579 2.0855 2 2WCM161_Z6_1 12 133780161 133810868 −0.2809 0.6659 NA NA NA NAWCM161_Z6_1 13 19600515 22178275 1.3703 3.0347 NA NA NA NA WCM161_Z6_113 22246093 26145827 −0.8334 −0.7261 1.1517 0.0573 1 0 WCM161_Z6_1 1326148963 28368049 −0.0377 1.1065 NA NA NA NA WCM161_Z6_1 13 2849428134098379 −0.7851 −0.5644 1.6751 −0.3227 2 0 WCM161_Z6_1 13 3439239535517179 0.5218 1.9576 NA NA NA NA WCM161_Z6_1 13 35615073 37453779−0.9112 −1.0175 NA NA NA NA WCM161_Z6_1 13 37524190 40362473 1.16562.7891 NA NA NA NA WCM161_Z6_1 13 41133851 42893343 −0.8707 −0.8605 NANA NA NA WCM161_Z6_1 13 43148455 46616337 1.2857 2.9341 NA NA NA NAWCM161_Z6_1 13 46619175 55748666 −0.8669 −0.8463 1.0559 0.0565 1 0WCM161_Z6_1 13 58206799 95235475 −0.41 0.4031 1.4183 1.2264 1 1WCM161_Z6_1 13 95244526 101287127 −0.922 −1.0614 1.1125 −0.1542 1 0WCM161_Z6_1 13 101287404 115089411 −0.1501 0.9103 2.6432 1.1157 3 1WCM161_Z6_1 14 19377712 50998731 0.1208 1.3659 3.1034 2.0514 3 2WCM161_Z6_1 14 51027017 87387822 −0.2978 0.6329 2.1456 0.9558 2 1WCM161_Z6_1 14 88400339 107283019 0.177 1.4539 3.3925 2.0867 3 2WCM161_Z6_1 15 20170134 102506284 −0.2925 0.6433 2.1375 0.9863 2 1WCM161_Z6_1 16 67604 72827432 −0.0624 1.0644 2.1559 2.0266 2 2WCM161_Z6_1 16 72827758 90233622 −0.5499 0.0861 2.0886 0.0343 2 0WCM161_Z6_1 17 131595 21194820 −0.2947 0.6389 3.1774 −0.0632 3 0WCM161_Z6_1 17 21199037 21319868 0.0628 1.2731 2.6479 2.1857 3 2WCM161_Z6_1 17 21438747 71746796 0.1375 1.3922 3.1611 2.0886 3 2WCM161_Z6_1 17 71757115 74921130 0.3059 1.6488 3.2423 3.029 3 3WCM161_Z6_1 17 74922755 81083381 −0.0494 1.0866 3.2979 0.9497 3 1WCM161_Z6_1 18 48338 216486 0.0665 1.2792 NA NA NA NA WCM161_Z6_1 18218887 15006027 0.4897 1.9129 5.7245 1.8068 6 2 WCM161_Z6_1 18 1853134531324171 0.1846 1.4657 3.6272 1.8968 4 2 WCM161_Z6_1 18 3132456339647378 0.4068 1.7956 6.1065 0.8366 6 1 WCM161_Z6_1 18 4032345646343666 0.0516 1.255 3.5099 1.2634 4 1 WCM161_Z6_1 18 46383964 78005224−0.4228 0.3755 1.384 1.2106 1 1 WCM161_Z6_1 19 281445 651785 −0.55680.0694 2.1787 −0.08 2 0 WCM161_Z6_1 19 652238 1581250 0.4225 1.81814.6117 2.4404 5 2 WCM161_Z6_1 19 1582673 9251258 −0.5375 0.1157 2.10140.0656 2 0 WCM161_Z6_1 19 9266691 9406900 0.5188 1.9534 NA NA NA NAWCM161_Z6_1 19 9406953 14991963 0.4787 1.8975 5.3091 2.1423 5 2WCM161_Z6_1 19 14992157 34304214 0.182 1.4617 3.303 2.2054 3 2WCM161_Z6_1 19 34513673 57088843 −0.5341 0.124 2.1878 −0.0083 2 0WCM161_Z6_1 19 57088850 59083985 −0.268 0.6909 2.2122 1.0163 2 1WCM161_Z6_1 2 41612 242946607 −0.281 0.6658 2.1482 1.0247 2 1WCM161_Z6_1 20 68406 62904835 −0.054 1.0788 2.1268 2.0979 2 2WCM161_Z6_1 21 9826235 39822803 −0.2284 0.7663 2.45 0.9519 2 1WCM161_Z6_1 21 39947594 42866388 0.7651 2.2848 8.7284 1.0173 9 1WCM161_Z6_1 21 42870082 48084277 −0.2704 0.6862 2.1873 1.0307 2 1WCM161_Z6_1 22 17063485 18256374 −0.2692 0.6886 NA NA NA NA WCM161_Z6_122 18257224 40831521 0.1049 1.3407 2.807 2.2585 3 2 WCM161_Z6_1 2240859256 51215134 −0.2901 0.6479 2.2048 0.929 2 1 WCM161_Z6_1 3 2393777603260 −0.1328 0.9412 NA NA NA NA WCM161_Z6_1 3 7620382 8705555 0.28881.6235 NA NA NA NA WCM161_Z6_1 3 8757555 49679822 0.1289 1.3788 4.26530.9357 4 1 WCM161_Z6_1 3 49680066 87289860 0.2911 1.6269 4.1575 2.0193 42 WCM161_Z6_1 3 87295049 170585946 0.073 1.2897 2.7958 2.0936 3 2WCM161_Z6_1 3 170586128 197894726 −0.0956 1.0069 2.0904 1.9289 2 2WCM161_Z6_1 4 59331 8098834 −0.0621 1.0649 3.1409 1.0432 3 1 WCM161_Z6_14 8108325 49046830 −0.2882 0.6517 2.1453 0.9967 2 1 WCM161_Z6_1 449052752 55127300 0.4755 1.893 NA NA NA NA WCM161_Z6_1 4 5512753357976281 −0.3407 0.5472 NA NA NA NA WCM161_Z6_1 4 57976427 773057590.7413 2.2536 8.5676 0.9699 9 1 WCM161_Z6_1 4 77324327 82090890 −0.31760.5936 1.6685 1.3495 2 1 WCM161_Z6_1 4 82092915 89052995 0.6709 2.16038.2016 0.7388 8 1 WCM161_Z6_1 4 89053781 119472275 −0.2832 0.6613 2.10541.0577 2 1 WCM161_Z6_1 4 119606698 126428439 0.6241 2.0976 7.4992 1.06057 1 WCM161_Z6_1 4 128544578 139966271 −0.2481 0.729 NA NA NA NAWCM161_Z6_1 4 139966467 164087809 0.5101 1.9413 6.3931 1.2877 6 1WCM161_Z6_1 4 164246708 166408681 −0.3494 0.5296 NA NA NA NA WCM161_Z6_14 166414332 178911657 0.5103 1.9416 6.7684 0.9143 7 1 WCM161_Z6_1 4183090455 190426502 −0.3304 0.5679 2.1326 0.8322 2 1 WCM161_Z6_1 5140627 228448 −0.0321 1.116 NA NA NA NA WCM161_Z6_1 5 231001 1422546790.0756 1.2938 2.5031 2.4003 3 2 WCM161_Z6_1 5 142258986 180687814−0.1137 0.9752 1.9971 1.9347 2 2 WCM161_Z6_1 6 203466 170892825 −0.29160.645 2.0601 1.0674 2 1 WCM161_Z6_1 7 193265 12417407 0.0057 1.17942.7542 1.7754 3 2 WCM161_Z6_1 7 12419108 45148667 0.3257 1.678 4.40781.992 4 2 WCM161_Z6_1 7 45148773 45960731 0.2856 1.6188 NA NA NA NAWCM161_Z6_1 7 45961271 82582228 −0.0315 1.117 4.1025 0.2354 4 0WCM161_Z6_1 7 82582513 104681442 0.2426 1.5542 3.7885 2.0848 4 2WCM161_Z6_1 7 104702680 138593771 −0.1612 0.8902 3.8286 −0.1217 4 0WCM161_Z6_1 7 138596064 143632984 −0.0859 1.0237 3.7538 0.3125 4 0WCM161_Z6_1 7 143633157 158937011 −0.1312 0.9441 3.862 −0.014 4 0WCM161_Z6_1 8 190897 32621438 −0.5747 0.0255 2.1181 −0.0825 2 0WCM161_Z6_1 8 33230313 35453147 1.3199 2.9749 NA NA NA NA WCM161_Z6_1 835541126 126370010 1.2418 2.8814 12.5478 2.1893 13  2 WCM161_Z6_1 8126379041 146279479 1.3846 3.0516 14.284 2.2991 14  2 WCM161_Z6_1 917101 141111414 0.0219 1.2062 2.3377 2.2768 2 2 WCM161_Z6_1 X 270768214937881 0.0083 1.1837 NA NA NA NA WCM161_Z6_1 X 15262636 376414160.9644 2.5403 NA NA NA NA WCM161_Z6_1 X 37642778 42637017 1.468 3.1495NA NA NA NA WCM161_Z6_1 X 42637040 64137685 0.9294 2.4961 NA NA NA NAWCM161_Z6_1 X 64138962 67652739 2.3359 4.1237 NA NA NA NA WCM161_Z6_1 X67731711 154509348 −0.1036 0.9928 NA NA NA NA WCM162 1 14930 1002932−0.2114 −0.0502 1.1258 0.8058 1 1 WCM162 1 1004565 1636379 −0.6388−0.9304 1.0159 0.0335 1 0 WCM162 1 1638780 3683090 0.2638 0.7109 1.72291.5507 2 2 WCM162 1 3683747 11354924 −0.2108 −0.0492 0.9665 0.9665 1 1WCM162 1 11561038 13933849 0.2561 0.6996 1.7359 1.5123 2 2 WCM162 113936822 17313157 −0.1231 0.1035 1.1128 1.036 1 1 WCM162 1 1731345420680271 0.2308 0.6625 1.688 1.4777 2 1 WCM162 1 20680662 21175861−0.2773 −0.1698 0.9481 0.8298 1 1 WCM162 1 21177773 24022911 −0.6247−0.8962 1.0036 0.071 1 0 WCM162 1 24075460 29010295 −0.16 0.0401 1.02821.0282 1 1 WCM162 1 29016716 31186387 0.542 1.1013 NA NA NA NA WCM162 131187116 55969890 −0.1922 −0.0162 0.9889 0.9889 1 1 WCM162 1 5597013491182847 0.0613 0.4046 1.3237 1.3237 1 1 WCM162 1 91380919 924980240.6584 1.2565 3.8384 0.94 4 1 WCM162 1 92508428 99418879 −0.2823 −0.1790.8833 0.8833 1 1 WCM162 1 99422203 110876376 0.0548 0.3943 1.40331.2254 1 1 WCM162 1 110882174 145687061 −0.1198 0.1091 1.0785 1.0785 1 1WCM162 1 145687155 152384759 0.3428 0.8249 1.822 1.721 2 2 WCM162 1152483959 157963503 −0.0395 0.243 1.1835 1.1835 1 1 WCM162 1 158045072160209979 0.6745 1.2777 3.5848 1.2642 4 1 WCM162 1 160210223 1623451890.3502 0.8354 2.3455 1.2233 2 1 WCM162 1 162346496 163046227 0.17050.5725 NA NA NA NA WCM162 1 163114605 169890854 −0.3388 −0.2856 1.58570.055 2 0 WCM162 1 169923219 181724537 −0.6337 −0.9179 1.0427 0.0158 1 0WCM162 1 181725167 183853056 −0.2011 −0.0319 1.9847 −0.0285 2 0 WCM162 1183853985 203819595 0.1076 0.4767 1.4388 1.3444 1 1 WCM162 1 203820303207532965 0.6028 1.1829 3.4136 1.127 3 1 WCM162 1 207635031 222892214−0.0253 0.2662 1.2026 1.2026 1 1 WCM162 1 222892601 228612921 0.26080.7066 1.8611 1.4029 2 1 WCM162 1 228645113 237994957 −0.1902 −0.01260.9913 0.9913 1 1 WCM162 1 237995938 246021881 0.2643 0.7117 1.7311.5444 2 2 WCM162 1 246027253 249213967 −0.1159 0.1158 1.0836 1.0836 1 1WCM162 10 225910 43089731 −0.073 0.1877 1.139 1.139 1 1 WCM162 1043089949 54074415 −0.59 −0.8141 1.1496 −0.0121 1 0 WCM162 10 5407466069647342 −0.132 0.0883 1.0631 1.0631 1 1 WCM162 10 69648749 718353990.2871 0.7448 1.7657 1.5859 2 2 WCM162 10 71849793 79814784 −0.06490.2011 1.1496 1.1496 1 1 WCM162 10 80029759 82405911 0.4591 0.98812.7256 1.2416 3 1 WCM162 10 83635560 97810219 −0.0928 0.1547 1.11321.1132 1 1 WCM162 10 97816773 102283647 0.504 1.0497 2.8468 1.2934 3 1WCM162 10 102286222 102510673 0.1344 0.5178 NA NA NA NA WCM162 10102539321 105048293 −0.2956 −0.2038 0.8683 0.8683 1 1 WCM162 10105048435 108334796 0.1981 0.6139 1.816 1.2448 2 1 WCM162 10 108335627120907203 −0.6421 −0.9384 0.9455 0.0981 1 0 WCM162 10 120914530123239438 −0.1276 0.0958 1.22 0.9174 1 1 WCM162 10 123241737 1349818370.2653 0.7131 1.7422 1.5364 2 2 WCM162 10 134996974 135477898 −0.1939−0.0193 1.0703 0.9032 1 1 WCM162 11 193096 1021268 −0.1529 0.0525 1.09080.9833 1 1 WCM162 11 1023485 2905091 0.2911 0.7507 2.1626 1.2025 2 1WCM162 11 2905297 9519351 −0.1874 −0.0077 0.9947 0.9947 1 1 WCM162 119522712 18108492 0.1195 0.4949 1.4633 1.3551 1 1 WCM162 11 1810868743340140 −0.1466 0.0632 1.0448 1.0448 1 1 WCM162 11 43342439 464734540.1928 0.606 1.736 1.308 2 1 WCM162 11 46515196 47799857 −0.3097 −0.23020.8573 0.8477 1 1 WCM162 11 47800351 55036774 0.3009 0.7648 2.06711.3311 2 1 WCM162 11 55038033 62296346 −0.1043 0.1353 1.0983 1.0983 1 1WCM162 11 62296703 65743928 −0.3245 −0.2582 0.8362 0.8362 1 1 WCM162 1165744493 67012860 0.053 0.3916 1.4854 1.1383 1 1 WCM162 11 6701360070013506 0.6188 1.2041 3.1236 1.4843 3 1 WCM162 11 70014114 113566153−0.1433 0.0689 1.0489 1.0489 1 1 WCM162 11 113567679 117076026 −0.4464−0.4997 0.7935 0.621 1 1 WCM162 11 117076048 134605954 −0.0434 0.23661.1782 1.1782 1 1 WCM162 12 148452 2602428 0.0981 0.4619 1.5756 1.1791 21 WCM162 12 2613521 3768751 0.7029 1.3147 3.5477 1.4275 4 1 WCM162 123782578 10324618 0.2627 0.7094 1.6853 1.5849 2 2 WCM162 12 1033217725706018 −0.1713 0.0205 1.0143 1.0143 1 1 WCM162 12 25801446 383279060.4527 0.9792 2.1486 1.7943 2 2 WCM162 12 38362752 55361593 −0.1891−0.0106 0.9927 0.9927 1 1 WCM162 12 55367178 57112802 0.135 0.51861.4326 1.4326 1 1 WCM162 12 57113144 58240199 0.529 1.0836 2.1567 2.0822 2 WCM162 12 58335495 66537186 −0.1249 0.1004 1.2054 0.9387 1 1 WCM16212 66539585 71519125 0.4479 0.9726 2.8834 1.0414 3 1 WCM162 12 7152311194727444 −0.1462 0.0639 1.0759 1.0147 1 1 WCM162 12 94729482 972228700.4391 0.9604 2.8558 1.0359 3 1 WCM162 12 97254620 105198607 −0.2192−0.064 0.9566 0.9566 1 1 WCM162 12 105199021 110390335 0.428 0.94492.6513 1.199 3 1 WCM162 12 110391038 116397465 −0.2248 −0.0741 0.97210.9278 1 1 WCM162 12 116397584 120806700 0.3701 0.8637 1.8197 1.8197 2 2WCM162 12 120875914 123246794 −0.3197 −0.2492 0.8414 0.8414 1 1 WCM16212 123247491 124498969 0.5834 1.1569 3.504 0.9556 4 1 WCM162 12124499429 133810842 −0.1093 0.1269 1.0919 1.0919 1 1 WCM162 13 1904205936822838 0.2653 0.7132 2.0224 1.2564 2 1 WCM162 13 36828152 92380952−0.2485 −0.117 0.9221 0.9221 1 1 WCM162 13 92408638 112526718 −0.00140.305 1.2413 1.2294 1 1 WCM162 13 112527826 115089411 −0.2195 −0.06460.9562 0.9562 1 1 WCM162 14 19110392 36005387 −0.2387 −0.0992 0.93360.9336 1 1 WCM162 14 36005659 38277999 0.2333 0.6661 1.7132 1.4604 2 1WCM162 14 38281452 54897173 −0.3379 −0.2839 0.8214 0.8214 1 1 WCM162 1454898917 60470474 0.0587 0.4005 1.3531 1.2867 1 1 WCM162 14 6047054275748011 −0.1533 0.0516 1.0364 1.0364 1 1 WCM162 14 75748361 787095780.323 0.7967 1.8692 1.6051 2 2 WCM162 14 78709776 94756701 −0.135 0.08321.0593 1.0593 1 1 WCM162 14 94756968 99880213 0.2111 0.6332 1.97981.1222 2 1 WCM162 14 99924727 100615442 0.8247 1.4716 4.3395 1.207 4 1WCM162 14 100615561 106385364 0.3519 0.8379 1.8332 1.7417 2 2 WCM162 14106386996 107283255 0.1651 0.5643 NA NA NA NA WCM162 15 2008389651250610 −0.1511 0.0556 1.0393 1.0393 1 1 WCM162 15 51250944 548178190.2262 0.6557 1.6429 1.5078 2 2 WCM162 15 54825172 75759536 −0.17670.011 1.0076 1.0076 1 1 WCM162 15 75760095 78346326 0.5481 1.1094 3.53210.7832 4 1 WCM162 15 78358330 80464560 −0.2089 −0.0458 0.9687 0.9687 1 1WCM162 15 80465300 85191184 0.313 0.7822 2.1082 1.3313 2 1 WCM162 1585191825 102516227 −0.1066 0.1314 1.0954 1.0954 1 1 WCM162 16 644003788610 −0.2216 −0.0684 0.9537 0.9537 1 1 WCM162 16 3789581 51454050.3861 0.8864 2.5331 1.1639 3 1 WCM162 16 5147665 10576420 −0.1785 0.0081.0055 1.0055 1 1 WCM162 16 10624302 13297242 0.4115 0.9219 2.76341.0257 3 1 WCM162 16 13307046 18817489 −0.1798 0.0055 1.0038 1.0038 1 1WCM162 16 18817730 18882673 0.0723 0.4218 NA NA NA NA WCM162 16 1888359220605121 0.9364 1.6121 4.917 1.1971 5 1 WCM162 16 20634764 212618560.2186 0.6444 NA NA NA NA WCM162 16 21261989 27789278 −0.0844 0.16871.124 1.124 1 1 WCM162 16 27789831 29814805 0.3731 0.868 2.5758 1.0745 31 WCM162 16 29815328 30667618 −0.0994 0.1436 1.2181 0.9913 1 1 WCM162 1630671691 32941839 0.3789 0.8761 1.8354 1.8354 2 2 WCM162 16 3294534165390380 −0.1634 0.0341 1.0239 1.0239 1 1 WCM162 16 65397073 674400750.3797 0.8773 1.8369 1.8369 2 2 WCM162 16 67440339 70818759 −0.13720.0793 1.0819 1.0312 1 1 WCM162 16 70819754 71127657 −0.3441 −0.2959 NANA NA NA WCM162 16 71209574 88502662 −0.6917 −1.063 0.9657 −0.0084 1 0WCM162 16 88502933 90124889 −0.3724 −0.3508 1.6411 −0.0728 2 0 WCM162 1690125408 90168693 0.0311 0.3569 NA NA NA NA WCM162 17 131595 8638800−0.0709 0.1912 1.1417 1.1417 1 1 WCM162 17 8644766 11882027 0.482 1.01962.0274 2.0274 2 2 WCM162 17 11886699 28999184 0.0509 0.3882 1.40371.2138 1 1 WCM162 17 29059119 29219818 −0.392 −0.3895 NA NA NA NA WCM16217 29220389 37561613 −0.6758 −1.0222 0.9424 0.0423 1 0 WCM162 1737563252 38956108 −0.2447 −0.11 1.9637 −0.1106 2 0 WCM162 17 3897470741622705 −0.7545 −1.2306 0.8866 −0.0343 1 0 WCM162 17 41623030 44271152−0.2686 −0.1536 1.9109 −0.1129 2 0 WCM162 17 44788445 45760741 0.06280.4069 NA NA NA NA WCM162 17 45760961 48072078 0.6638 1.2636 3.42641.3754 3 1 WCM162 17 48072344 57350263 0.032 0.3583 1.2962 1.2677 1 1WCM162 17 57351017 60142547 0.5348 1.0915 3.1061 1.1557 3 1 WCM162 1760215513 71427648 −0.1976 −0.0256 0.9824 0.9824 1 1 WCM162 17 7142994972765215 0.3089 0.7763 1.957 1.4685 2 1 WCM162 17 72768124 735042681.1021 1.8161 5.6034 1.439 6 1 WCM162 17 73509765 81052609 0.0798 0.43351.4179 1.2832 1 1 WCM162 18 47680 78005245 −0.1088 0.1278 1.0926 1.09261 1 WCM162 19 104963 362418 −0.3526 −0.3122 NA NA NA NA WCM162 19 3671003281149 0.2067 0.6268 1.5947 1.4936 2 1 WCM162 19 3282053 13319842−0.1881 −0.0089 0.9939 0.9939 1 1 WCM162 19 13321452 16136395 0.10240.4686 1.3837 1.3837 1 1 WCM162 19 16136636 42930955 −0.1939 −0.01910.9869 0.9869 1 1 WCM162 19 42931202 45397249 0.2654 0.7133 1.97951.2996 2 1 WCM162 19 45404020 59093645 −0.2074 −0.0432 0.9705 0.9705 1 1WCM162 2 41474 1079242 −0.1624 0.036 1.3011 0.7494 1 1 WCM162 2 107939614774018 0.2321 0.6644 1.6714 1.4983 2 1 WCM162 2 14774374 25194741−0.1889 −0.0103 0.9929 0.9929 1 1 WCM162 2 25306119 26818100 0.13570.5198 1.5716 1.2959 2 1 WCM162 2 26828459 29136874 −0.2856 −0.18510.8796 0.8796 1 1 WCM162 2 29137129 36774339 0.1014 0.4671 1.44 1.3247 11 WCM162 2 36775661 51259378 −0.2516 −0.1226 0.9185 0.9185 1 1 WCM162 251662228 65540794 0.207 0.6273 1.8274 1.2618 2 1 WCM162 2 6554090586831060 −0.2083 −0.0447 0.9695 0.9695 1 1 WCM162 2 86831148 103433142−0.0361 0.2486 1.223 1.1531 1 1 WCM162 2 105185363 112944976 0.18870.5998 1.5791 1.452 2 1 WCM162 2 112988488 138722273 −0.1564 0.04631.0326 1.0326 1 1 WCM162 2 138724524 144525805 0.4922 1.0335 2.42521.6688 2 2 WCM162 2 144699787 169551552 −0.0479 0.2292 1.2049 1.1394 1 1WCM162 2 169571466 170428398 0.3899 0.8916 2.3641 1.3464 2 1 WCM162 2170440959 207621974 −0.0657 0.1999 1.1486 1.1486 1 1 WCM162 2 207622091216300375 −0.2166 −0.0595 0.9596 0.9596 1 1 WCM162 2 216743547 2199427900.349 0.8337 2.5255 1.039 3 1 WCM162 2 219959961 232327894 −0.15470.0492 1.0347 1.0347 1 1 WCM162 2 232329052 234741227 0.1433 0.53141.5575 1.3331 2 1 WCM162 2 234741739 243052762 −0.2043 −0.0375 0.97430.9743 1 1 WCM162 20 68312 6760367 −0.186 −0.0052 0.9964 0.9964 1 1WCM162 20 6760770 14066276 0.4127 0.9236 2.5226 1.2712 3 1 WCM162 2014066797 46307567 −0.1821 0.0016 1.0011 1.0011 1 1 WCM162 20 4631186655749953 0.1226 0.4996 1.4963 1.3315 1 1 WCM162 20 55758827 584415000.613 1.1965 2.2918 2.2918 2 2 WCM162 20 58441609 60808435 0.0596 0.40191.56 1.0826 2 1 WCM162 20 60831247 62934623 −0.1902 −0.0127 0.99120.9912 1 1 WCM162 21 9590271 45008625 −0.1962 −0.0232 0.984 0.984 1 1WCM162 21 45012148 47545534 0.1643 0.5632 1.578 1.3771 2 1 WCM162 2147545922 48084175 −0.3315 −0.2716 0.8284 0.8284 1 1 WCM162 22 1615906024181169 0.3801 0.8779 2.3691 1.3063 2 1 WCM162 22 24199151 40859315−0.2087 −0.0453 0.9691 0.9691 1 1 WCM162 22 40915494 49146061 0.09940.464 1.3793 1.3793 1 1 WCM162 22 49146347 51219090 −0.3264 −0.26180.834 0.834 1 1 WCM162 3 239524 9990294 −0.1145 0.1181 1.0853 1.0853 1 1WCM162 3 9991041 13860590 0.386 0.8862 2.4104 1.2861 2 1 WCM162 313860873 38042439 −0.079 0.1778 1.1311 1.1311 1 1 WCM162 3 3804285038991885 0.4486 0.9735 2.7518 1.1754 3 1 WCM162 3 39093406 47870459−0.1642 0.0329 1.023 1.023 1 1 WCM162 3 47882481 49753788 0.2944 0.75541.7541 1.6222 2 2 WCM162 3 49755498 50683265 −0.2364 −0.0951 NA NA NA NAWCM162 3 50683692 54352241 0.1352 0.519 1.5379 1.3279 2 1 WCM162 354354431 63953527 −0.1493 0.0587 1.0415 1.0415 1 1 WCM162 3 6396571267568710 0.3416 0.8232 2.7233 0.8154 3 1 WCM162 3 67570888 112301532−0.204 −0.0371 0.9746 0.9746 1 1 WCM162 3 112324305 133914095 0.17180.5745 1.7853 1.193 2 1 WCM162 3 133921683 197896724 −0.0989 0.14451.1053 1.1053 1 1 WCM162 4 53423 15055789 −0.0408 0.2408 1.1817 1.1817 11 WCM162 4 15059988 17802412 0.4506 0.9763 2.9173 1.0175 3 1 WCM162 417803748 73148843 0.0342 0.3619 1.2994 1.2708 1 1 WCM162 4 7314931376434534 0.4143 0.9258 2.205 1.5945 2 2 WCM162 4 76439485 106638763−0.1734 0.0168 1.0117 1.0117 1 1 WCM162 4 106639102 113726300 0.25460.6975 1.9116 1.3318 2 1 WCM162 4 113728100 143029296 −0.1458 0.06471.0459 1.0459 1 1 WCM162 4 143033676 149357758 0.2187 0.6446 1.73241.3941 2 1 WCM162 4 149358014 166389045 −0.1847 −0.003 0.9979 0.9979 1 1WCM162 4 166403455 173704113 0.5416 1.1008 2.7129 1.5765 3 2 WCM162 4173730564 190903980 −0.0853 0.1673 1.123 1.123 1 1 WCM162 5 906965469124 −0.1437 0.0683 1.0485 1.0485 1 1 WCM162 5 5473728 418427460.0228 0.3436 1.2689 1.2689 1 1 WCM162 5 41850204 96512820 −0.2353−0.093 0.9375 0.9375 1 1 WCM162 5 96513453 109025747 −0.6421 −0.93831.0566 −0.0129 1 0 WCM162 5 109026194 109203296 −0.0536 0.2199 NA NA NANA WCM162 5 109668614 114860322 0.5379 1.0957 2.1372 2.1372 2 2 WCM162 5114860647 135469500 −0.1827  5.00E−04 1.0004 1.0004 1 1 WCM162 5135469770 137893545 0.5592 1.1244 3.0165 1.3438 3 1 WCM162 5 137894341140795145 −0.3669 −0.34 0.79 0.79 1 1 WCM162 5 140797493 161324532−0.0676 0.1968 1.1461 1.1461 1 1 WCM162 5 161325273 167182213 −0.299−0.21 0.8645 0.8645 1 1 WCM162 5 167182240 169714998 0.4445 0.96781.9559 1.9559 2 2 WCM162 5 169720203 180687847 −0.1809 0.0037 1.00261.0026 1 1 WCM162 6 203561 40996318 −0.1892 −0.0108 0.9925 0.9925 1 1WCM162 6 40998169 46135842 0.4062 0.9144 1.8848 1.8848 2 2 WCM162 646188487 73112380 −0.1425 0.0704 1.05 1.05 1 1 WCM162 6 7324824286181051 0.1073 0.4762 1.4898 1.2924 1 1 WCM162 6 86181214 99322151−0.2454 −0.1112 0.9258 0.9258 1 1 WCM162 6 99323323 102012757 0.72251.3402 3.9582 1.1057 4 1 WCM162 6 102069937 128841423 −0.1902 −0.01260.9913 0.9913 1 1 WCM162 6 129204447 134758977 −0.001 0.3056 1.54040.9314 2 1 WCM162 6 134785989 138763072 0.4518 0.9779 2.193 1.7462 2 2WCM162 6 138768206 159187640 0.0625 0.4065 1.3255 1.3255 1 1 WCM162 6159187941 170892848 −0.1688 0.0249 1.0174 1.0174 1 1 WCM162 7 1931892834585 −0.107 0.1308 1.0949 1.0949 1 1 WCM162 7 2839721 28547407 0.2110.6331 1.6224 1.4794 2 1 WCM162 7 28552418 32527304 0.7761 1.4095 2.71782.595 3 3 WCM162 7 32528216 48634325 0.3817 0.8801 2.536 1.1451 3 1WCM162 7 48634484 65705605 0.0669 0.4134 1.3318 1.3318 1 1 WCM162 765705779 79828710 0.3794 0.8768 1.9943 1.6783 2 2 WCM162 7 7982875392361119 −0.2407 −0.1028 0.9312 0.9312 1 1 WCM162 7 92367215 952163900.2253 0.6544 1.858 1.2899 2 1 WCM162 7 95216684 96765730 −0.1445 0.067NA NA NA NA WCM162 7 96810324 100088698 0.7505 1.3765 4.0639 1.1287 4 1WCM162 7 100092412 108524326 −0.2393 −0.1002 0.9717 0.8941 1 1 WCM162 7108524593 120737809 0.1082 0.4776 1.4504 1.3344 1 1 WCM162 7 120739990122001002 0.5855 1.1597 3.1815 1.2868 3 1 WCM162 7 122001089 141920843−0.04 0.2422 1.1828 1.1828 1 1 WCM162 7 141920981 146536869 0.54581.1064 3.2637 1.0424 3 1 WCM162 7 146590712 158828679 0.0611 0.40431.3608 1.286 1 1 WCM162 7 158829410 158937158 −0.2861 −0.1861 NA NA NANA WCM162 8 163461 12435678 −0.5474 −0.7169 1.1372 0.0796 1 0 WCM162 812493711 21549666 −0.2803 −0.1754 1.8121 −0.041 2 0 WCM162 8 2154971330610655 −0.6642 −0.993 0.9989 0.006 1 0 WCM162 8 30612148 68982167−0.1886 −0.0098 0.9932 0.9932 1 1 WCM162 8 68984721 74650536 0.48071.0178 2.5917 1.4578 3 1 WCM162 8 74692722 102644013 −0.1698 0.02311.0162 1.0162 1 1 WCM162 8 102644486 144644249 0.1987 0.6148 1.61131.4513 2 1 WCM162 8 144644623 145732226 0.6201 1.2058 3.5372 1.0761 4 1WCM162 8 145732395 145979138 0.1523 0.5451 1.6672 1.251 2 1 WCM162 8145979779 146279371 −0.1125 0.1215 1.1303 1.0455 1 1 WCM162 9 15883711396 0.1166 0.4905 1.4892 1.3207 1 1 WCM162 9 711743 78631328 0.36680.8591 1.9089 1.7189 2 2 WCM162 9 78638689 88457704 −0.0839 0.16961.1247 1.1247 1 1 WCM162 9 88460884 93637188 0.228 0.6584 2.0939 1.06282 1 WCM162 9 93639973 95477576 0.7243 1.3426 2.7433 2.3288 3 2 WCM162 995477693 97356033 0.1502 0.5417 1.5684 1.343 2 1 WCM162 9 97365642100088893 −0.1237 0.1025 1.0736 1.0736 1 1 WCM162 9 100090254 1019159160.3979 0.9029 1.9643 1.7754 2 2 WCM162 9 101979938 124241532 −0.1420.0711 1.0505 1.0505 1 1 WCM162 9 124329532 131831408 0.2007 0.61781.6559 1.4133 2 1 WCM162 9 131831971 141107532 −0.1224 0.1046 1.07521.0752 1 1 WCM162 X 2700189 43817834 −0.1442 0.0674 NA NA NA NA WCM162 X44008014 49593896 1.0019 1.6934 NA NA NA NA WCM162 X 49595103 647546010.2881 0.7463 NA NA NA NA WCM162 X 64887665 68840787 1.0303 1.7284 NA NANA NA WCM162 X 68844800 154493590 −0.0569 0.2144 NA NA NA NA WCM162_Z1_11 721450 1007837 −0.2375 0.1023 NA NA NA NA WCM162_Z1_1 1 10181441670405 −0.9737 −0.845 1.0784 0.0351 1 0 WCM162_Z1_1 1 1684475 37035010.2567 0.6796 1.9241 1.2794 2 1 WCM162_Z1_1 1 3703695 11595551 −0.27640.0553 1.0618 1.0164 1 1 WCM162_Z1_1 1 11596396 14220186 0.1632 0.57292.0235 0.9515 2 1 WCM162_Z1_1 1 14506932 17312660 −0.3123 0.0117 1.16160.8547 1 1 WCM162_Z1_1 1 17312787 20678580 0.1543 0.5627 1.9164 1.0376 21 WCM162_Z1_1 1 20680293 21231381 −0.2631 0.0715 NA NA NA NA WCM162_Z1_11 21267821 24076429 −1.0632 −0.9714 1.009 0.011 1 0 WCM162_Z1_1 124077432 28907543 −0.3079 0.0171 1.0341 0.9897 1 1 WCM162_Z1_1 128919190 31187101 0.7898 1.2726 NA NA NA NA WCM162_Z1_1 1 3118808961869783 −0.2998 0.027 1.035 1.0028 1 1 WCM162_Z1_1 1 61872311 639912670.339 0.7729 2.0944 1.3231 2 1 WCM162_Z1_1 1 63997633 65351941 −0.30760.0174 NA NA NA NA WCM162_Z1_1 1 65523519 70687455 0.3745 0.8129 2.29421.2192 2 1 WCM162_Z1_1 1 70694111 75608851 −0.2838 0.0464 1.1053 0.96 11 WCM162_Z1_1 1 75609547 76081549 0.1834 0.596 NA NA NA NA WCM162_Z1_1 176190494 78585145 0.6757 1.1476 NA NA NA NA WCM162_Z1_1 1 7859163887045830 0.2057 0.6215 2.1696 0.9074 2 1 WCM162_Z1_1 1 87100046 91182689−0.3028 0.0233 1.1077 0.9248 1 1 WCM162_Z1_1 1 91382424 92528654 0.96691.4648 NA NA NA NA WCM162_Z1_1 1 92546144 100111889 −0.3287 −0.00821.0368 0.9518 1 1 WCM162_Z1_1 1 100127889 110921508 0.1703 0.581 1.93671.055 2 1 WCM162_Z1_1 1 110921797 113933947 −0.2964 0.0311 1.0925 0.9511 1 WCM162_Z1_1 1 114092219 115537613 0.1866 0.5996 NA NA NA NAWCM162_Z1_1 1 115576068 145326086 −0.3065 0.0188 1.2867 0.7395 1 1WCM162_Z1_1 1 145367178 149877531 0.3357 0.7692 NA NA NA NA WCM162_Z1_11 149878317 152052703 0.6575 1.1276 NA NA NA NA WCM162_Z1_1 1 152052722152323132 0.2918 0.7195 2.2307 1.0625 2 1 WCM162_Z1_1 1 152323409153752448 −0.2872 0.0422 1.0997 0.9597 1 1 WCM162_Z1_1 1 153902813155319144 0.1556 0.5642 1.9285 1.0285 2 1 WCM162_Z1_1 1 155319384155942053 0.4995 0.9528 NA NA NA NA WCM162_Z1_1 1 155948165 157963481−0.3247 −0.0034 1.0354 0.9599 1 1 WCM162_Z1_1 1 158045960 1590024530.6429 1.1116 3.3866 0.9349 3 1 WCM162_Z1_1 1 159015238 160313230 0.96931.4673 4.2097 1.3206 4 1 WCM162_Z1_1 1 160313565 162769689 0.6558 1.12583.2413 1.123 3 1 WCM162_Z1_1 1 162773300 163325157 0.1554 0.5639 NA NANA NA WCM162_Z1_1 1 164529115 164818608 −0.4865 −0.2033 NA NA NA NAWCM162_Z1_1 1 164853793 167734968 −0.9736 −0.8449 NA NA NA NAWCM162_Z1_1 1 167741559 169857919 −0.2916 0.0369 2.0584 −0.0065 2 0WCM162_Z1_1 1 169890853 182027035 −1.0302 −0.9244 1.0434 0.0104 1 0WCM162_Z1_1 1 182353729 184023947 −0.2738 0.0585 2.1295 −0.0468 2 0WCM162_Z1_1 1 184041389 185704020 0.6979 1.172 NA NA NA NA WCM162_Z1_1 1185704178 190423920 −0.2548 0.0815 1.0901 1.0262 1 1 WCM162_Z1_1 1192127815 193218871 0.5973 1.0612 NA NA NA NA WCM162_Z1_1 1 193219820202152786 0.2026 0.6179 2.0346 1.0347 2 1 WCM162_Z1_1 1 202155661203139575 −0.2898 0.0391 NA NA NA NA WCM162_Z1_1 1 203140225 2041353890.1916 0.6054 NA NA NA NA WCM162_Z1_1 1 204159844 204966684 1.0563 1.561NA NA NA NA WCM162_Z1_1 1 204970302 207110638 0.6629 1.1336 3.44430.9438 3 1 WCM162_Z1_1 1 207110936 207532982 0.9344 1.4297 NA NA NA NAWCM162_Z1_1 1 207627820 209602666 −0.301 0.0255 1.0327 1.003 1 1WCM162_Z1_1 1 209603784 212788501 0.4091 0.8517 2.2965 1.3128 2 1WCM162_Z1_1 1 212791525 221057662 −0.2694 0.0638 1.0907 0.9997 1 1WCM162_Z1_1 1 221057972 228699923 0.0795 0.4764 1.649 1.1335 2 1WCM162_Z1_1 1 228786094 238053863 −0.2807 0.0501 1.0655 1.0052 1 1WCM162_Z1_1 1 240070851 242035574 0.1552 0.5636 1.9227 1.0332 2 1WCM162_Z1_1 1 242042206 245180554 0.6297 1.097 NA NA NA NA WCM162_Z1_1 1245222729 246670511 0.1851 0.598 NA NA NA NA WCM162_Z1_1 1 246704458249212550 −0.3197 0.0028 1.0215 0.9824 1 1 WCM162_Z1_1 10 225960 3827174−0.3258 −0.0048 1.0903 0.903 1 1 WCM162_Z1_1 10 4867218 6557025 0.15590.5644 1.8949 1.0627 2 1 WCM162_Z1_1 10 7205773 23326228 −0.231 0.11021.1105 1.0482 1 1 WCM162_Z1_1 10 23393134 25877958 0.1543 0.5626 NA NANA NA WCM162_Z1_1 10 25883204 28884783 −0.2327 0.1081 1.144 1.0117 1 1WCM162_Z1_1 10 28897226 33623304 0.3033 0.7325 2.2766 1.0464 2 1WCM162_Z1_1 10 34400305 43088922 −0.3176 0.0053 1.1455 0.8618 1 1WCM162_Z1_1 10 43089209 54531361 −1.0433 −0.943 1.0276 0.0127 1 0WCM162_Z1_1 10 55566501 69407257 −0.1049 0.2606 1.2291 1.1668 1 1WCM162_Z1_1 10 69556964 71392557 0.4322 0.8776 2.6046 1.0702 3 1WCM162_Z1_1 10 71392808 74702483 −0.2706 0.0624 1.0922 0.9961 1 1WCM162_Z1_1 10 74714366 74884074 0.2801 0.7062 NA NA NA NA WCM162_Z1_110 74884984 79784372 0.0605 0.4544 NA NA NA NA WCM162_Z1_1 10 7978481483637721 0.4902 0.9424 2.9966 0.8468 3 1 WCM162_Z1_1 10 8392651991533797 −0.2199 0.1235 1.1444 1.0344 1 1 WCM162_Z1_1 10 9250335795216670 0.2739 0.6992 NA NA NA NA WCM162_Z1_1 10 95237963 97810047−0.329 −0.0086 1.0341 0.954 1 1 WCM162_Z1_1 10 97816950 99024633 0.93791.4334 NA NA NA NA WCM162_Z1_1 10 99025716 99968470 1.2695 1.7889 5.9360.9748 6 1 WCM162_Z1_1 10 99968673 100195117 0.8512 1.3395 NA NA NA NAWCM162_Z1_1 10 100195405 102306918 0.5334 0.9905 2.031 1.9427 2 2WCM162_Z1_1 10 102307850 104866362 −0.2986 0.0284 NA NA NA NAWCM162_Z1_1 10 104899207 107023082 0.1946 0.6088 1.975 1.0749 2 1WCM162_Z1_1 10 108337198 120907359 −0.9835 −0.8586 1.0858 0.0172 1 0WCM162_Z1_1 10 120914657 123233909 −0.0556 0.3188 NA NA NA NAWCM162_Z1_1 10 123239130 128076689 0.2623 0.686 2.161 1.0567 2 1WCM162_Z1_1 10 128114649 131977604 0.7715 1.2526 3.2545 1.511 3 2WCM162_Z1_1 10 132760893 134751028 0.2433 0.6644 1.8881 1.2818 2 1WCM162_Z1_1 10 134752203 135440090 −0.312 0.0121 1.0428 0.974 1 1WCM162_Z1_1 11 130546 694936 −0.3459 −0.0292 1.0135 0.9464 1 1WCM162_Z1_1 11 695842 3069028 0.1583 0.5672 1.9681 0.9951 2 1WCM162_Z1_1 11 3076167 9187407 −0.3393 −0.0212 1.0047 0.9662 1 1WCM162_Z1_1 11 9191494 12023977 0.3059 0.7354 NA NA NA NA WCM162_Z1_1 1112029923 14004426 −0.2884 0.0407 NA NA NA NA WCM162_Z1_1 11 1406314018124802 0.2861 0.7131 1.9813 1.2973 2 1 WCM162_Z1_1 11 1812758142262610 −0.2172 0.1267 1.1324 1.0511 1 1 WCM162_Z1_1 11 4333372246419157 0.1772 0.5889 1.9315 1.0766 2 1 WCM162_Z1_1 11 4641929947786875 −0.3023 0.0239 1.0773 0.9562 1 1 WCM162_Z1_1 11 4778880650003964 0.171 0.5818 1.7576 1.2359 2 1 WCM162_Z1_1 11 51411495 57583447−0.3335 −0.0141 1.0157 0.9649 1 1 WCM162_Z1_1 11 57798493 59712725 0.2430.664 2.1437 1.0252 2 1 WCM162_Z1_1 11 59807988 65746353 −0.3158 0.00751.0284 0.9819 1 1 WCM162_Z1_1 11 65766151 67012772 0.3948 0.8357 2.56641.0031 3 1 WCM162_Z1_1 11 67013459 67079325 0.8782 1.3687 NA NA NA NAWCM162_Z1_1 11 67119449 67431185 1.294 1.8149 6.0826 0.9542 6 1WCM162_Z1_1 11 67431998 68483386 0.8952 1.3872 NA NA NA NA WCM162_Z1_111 68506201 70017016 0.3097 0.7397 2.3236 1.0161 2 1 WCM162_Z1_1 1170026131 94583354 −0.2656 0.0684 1.0675 1.0295 1 1 WCM162_Z1_1 1194587241 99690428 0.2048 0.6205 NA NA NA NA WCM162_Z1_1 11 99715699113684612 −0.2194 0.124 1.1199 1.0597 1 1 WCM162_Z1_1 11 113685956115102086 −1.0571 −0.9627 NA NA NA NA WCM162_Z1_1 11 115109260 121500245−0.3056 0.0199 1.0262 1.0015 1 1 WCM162_Z1_1 11 121970500 1247461800.1387 0.5447 1.9152 1.0022 2 1 WCM162_Z1_1 11 124747183 129321221−0.2668 0.067 1.083 1.012 1 1 WCM162_Z1_1 11 129722553 134856611 0.12960.5342 1.9251 0.9712 2 1 WCM162_Z1_1 12 148673 977409 −0.2331 0.1076 NANA NA NA WCM162_Z1_1 12 977723 990165 0.4113 0.8542 NA NA NA NAWCM162_Z1_1 12 990912 3659185 0.619 1.0852 3.3953 0.8481 3 1 WCM162_Z1_112 3661961 6729677 0.4819 0.9332 2.1905 1.6285 2 2 WCM162_Z1_1 126730054 7309199 0.1652 0.5751 2.0214 0.9582 2 1 WCM162_Z1_1 12 73094718693390 −0.3 0.0266 1.1004 0.9369 1 1 WCM162_Z1_1 12 8756901 103321920.1862 0.5992 1.9849 1.0449 2 1 WCM162_Z1_1 12 10335159 26026977 −0.21820.1255 1.1066 1.0751 1 1 WCM162_Z1_1 12 26208297 26277693 0.4701 0.9199NA NA NA NA WCM162_Z1_1 12 26348806 27934122 0.8818 1.3727 4.2777 0.90134 1 WCM162_Z1_1 12 27944736 31286878 0.1684 0.5788 1.891 1.0962 2 1WCM162_Z1_1 12 31297871 32975538 0.6808 1.1533 NA NA NA NA WCM162_Z1_112 32976997 34182560 0.2163 0.6337 NA NA NA NA WCM162_Z1_1 12 3871069743769276 −0.3221 −3.00E−04 1.1754 0.8242 1 1 WCM162_Z1_1 12 4377008744605113 0.2206 0.6386 NA NA NA NA WCM162_Z1_1 12 44693517 56079048−0.3146 0.0089 1.0405 0.9719 1 1 WCM162_Z1_1 12 56080039 56151297−0.1114 0.2529 NA NA NA NA WCM162_Z1_1 12 56182862 57132299 0.28580.7127 1.7764 1.5014 2 2 WCM162_Z1_1 12 57133140 58240165 0.6561 1.1262.3579 2.0072 2 2 WCM162_Z1_1 12 58335505 60173312 −0.2802 0.0508 NA NANA NA WCM162_Z1_1 12 62104159 63359409 0.4925 0.9449 NA NA NA NAWCM162_Z1_1 12 63541330 65762800 −0.2726 0.0599 NA NA NA NA WCM162_Z1_112 65847540 68726027 0.4018 0.8435 2.6322 0.9566 3 1 WCM162_Z1_1 1269021118 70249147 0.9797 1.4786 NA NA NA NA WCM162_Z1_1 12 7027297971314166 0.5648 1.0253 NA NA NA NA WCM162_Z1_1 12 71441459 94727342−0.1291 0.2319 1.4727 0.8761 1 1 WCM162_Z1_1 12 94729371 97019519 0.63921.1075 3.3726 0.9367 3 1 WCM162_Z1_1 12 97020673 105239727 −0.28350.0467 1.093 0.9728 1 1 WCM162_Z1_1 12 105255146 106770201 0.5478 1.0065NA NA NA NA WCM162_Z1_1 12 106772118 108917393 0.1184 0.5214 NA NA NA NAWCM162_Z1_1 12 108918098 110405308 0.7215 1.1979 3.6815 0.9065 4 1WCM162_Z1_1 12 110418806 115120993 −0.2952 0.0325 1.0402 1.0054 1 1WCM162_Z1_1 12 115801897 121018950 0.4752 0.9256 1.9864 1.8126 2 2WCM162_Z1_1 12 121079121 123247467 −0.3196 0.0028 1.0533 0.9507 1 1WCM162_Z1_1 12 123249924 124497473 0.8417 1.3291 4.0177 1.0071 4 1WCM162_Z1_1 12 124796472 133810855 −0.2223 0.1205 1.1263 1.0479 1 1WCM162_Z1_1 13 19600364 20077375 0.1434 0.5501 NA NA NA NA WCM162_Z1_113 20208095 31835189 0.4214 0.8655 2.4487 1.1952 2 1 WCM162_Z1_1 1331843397 37015300 0.0086 0.3939 1.6974 0.9306 2 1 WCM162_Z1_1 1337016366 83597934 −0.7341 −0.5209 1.004 0.3899 1 0 WCM162_Z1_1 1384453741 112324768 −0.4977 −0.2174 1.1019 0.6183 1 1 WCM162_Z1_1 13112721971 115089411 −0.1596 0.1957 1.2517 1.0388 1 1 WCM162_Z1_1 1419377698 22938326 −0.3045 0.0213 1.0568 0.9729 1 1 WCM162_Z1_1 1422938596 25101196 −0.0985 0.2682 1.2541 1.1545 1 1 WCM162_Z1_1 1425101548 35592765 −0.2757 0.0562 1.0913 0.9881 1 1 WCM162_Z1_1 1435593030 38281564 0.2297 0.6489 1.9577 1.1783 2 1 WCM162_Z1_1 1438286843 54878241 −0.2448 0.0935 1.1223 1.0116 1 1 WCM162_Z1_1 1454878523 60474840 0.1886 0.602 1.9903 1.0452 2 1 WCM162_Z1_1 14 6048338369619622 −0.2653 0.0687 1.1021 0.9955 1 1 WCM162_Z1_1 14 6967646072176353 0.2925 0.7202 1.7221 1.5728 2 2 WCM162_Z1_1 14 7219039975989077 −0.3135 0.0103 1.0391 0.9753 1 1 WCM162_Z1_1 14 7599144778374178 0.3474 0.7823 2.2009 1.2389 2 1 WCM162_Z1_1 14 7839082791467486 −0.0984 0.2683 1.2613 1.1474 1 1 WCM162_Z1_1 14 9159283292905707 0.3877 0.8277 2.6584 0.8914 3 1 WCM162_Z1_1 14 9290843493998910 0.0444 0.4357 NA NA NA NA WCM162_Z1_1 14 94004472 94756690−0.3146 0.0089 NA NA NA NA WCM162_Z1_1 14 94756794 98444444 0.15490.5634 1.9614 0.994 2 1 WCM162_Z1_1 14 99182575 100625907 0.8347 1.3214NA NA NA NA WCM162_Z1_1 14 100705782 102843174 0.2484 0.6702 2.0151.1675 2 1 WCM162_Z1_1 14 102873682 104710651 0.7451 1.2238 2.471 2.20022 2 WCM162_Z1_1 14 104979232 106354418 0.2996 0.7283 2.3096 1.0038 2 1WCM162_Z1_1 14 106357053 107283183 −0.331 −0.0111 NA NA NA NAWCM162_Z1_1 15 20170091 24924482 −0.3211 0.0011 1.4242 0.5773 1 1WCM162_Z1_1 15 25200208 31197002 −0.016 0.3652 1.3876 1.1886 1 1WCM162_Z1_1 15 31197491 34782582 −0.3167 0.0064 1.0277 0.9812 1 1WCM162_Z1_1 15 34812832 40556114 −0.0479 0.3278 1.4969 1.0132 1 1WCM162_Z1_1 15 40557098 40764390 0.6189 1.0851 NA NA NA NA WCM162_Z1_115 40820970 51204336 −0.278 0.0534 1.0565 1.0188 1 1 WCM162_Z1_1 1551216153 54557613 0.3521 0.7876 NA NA NA NA WCM162_Z1_1 15 5458616759430546 −0.2885 0.0406 1.0685 0.9886 1 1 WCM162_Z1_1 15 5944586962146674 0.1432 0.5498 NA NA NA NA WCM162_Z1_1 15 62147082 68126118−0.2589 0.0765 1.1156 0.9933 1 1 WCM162_Z1_1 15 68346664 72226021 0.04770.4395 1.4507 1.2616 1 1 WCM162_Z1_1 15 72227724 73635840 0.4612 0.9101NA NA NA NA WCM162_Z1_1 15 73636038 74315444 0.0607 0.4546 NA NA NA NAWCM162_Z1_1 15 74315733 75722690 −0.312 0.0122 NA NA NA NA WCM162_Z1_115 75761206 78358391 0.3159 0.7468 2.4143 0.9418 2 1 WCM162_Z1_1 1578369815 81289814 −0.6019 −0.3494 1.0139 0.5559 1 1 WCM162_Z1_1 1581294795 85399751 0.1269 0.5311 2.0043 0.8857 2 1 WCM162_Z1_1 1585399874 89876384 −0.2798 0.0512 1.0863 0.9859 1 1 WCM162_Z1_1 1589876725 90984776 0.1715 0.5823 1.9436 1.0509 2 1 WCM162_Z1_1 1590986676 102517666 −0.2631 0.0714 1.1041 0.9974 1 1 WCM162_Z1_1 16 66953111914 −0.3445 −0.0276 NA NA NA NA WCM162_Z1_1 16 112689 3778115 −0.31050.014 1.0245 0.995 1 1 WCM162_Z1_1 16 3778320 5517243 0.5075 0.96172.8816 1.0136 3 1 WCM162_Z1_1 16 5649083 10912024 −0.2403 0.099 NA NA NANA WCM162_Z1_1 16 10960357 12996399 0.5482 1.0068 2.9612 1.0577 3 1WCM162_Z1_1 16 13002434 18441854 −0.3225 −8.00E−04 1.0434 0.9556 1 1WCM162_Z1_1 16 18539351 18908256 0.2857 0.7125 NA NA NA NA WCM162_Z1_116 19020719 20566621 1.1573 1.6692 NA NA NA NA WCM162_Z1_1 16 2063480621136559 0.1544 0.5627 NA NA NA NA WCM162_Z1_1 16 21139130 22826387−0.3262 −0.0052 1.0366 0.9563 1 1 WCM162_Z1_1 16 22926511 241661300.1626 0.5722 NA NA NA NA WCM162_Z1_1 16 24183647 27802781 −0.29960.0272 NA NA NA NA WCM162_Z1_1 16 27818833 29820906 0.5157 0.9708 3.00820.9116 3 1 WCM162_Z1_1 16 29821596 30676211 0.0349 0.4246 1.5952 1.08922 1 WCM162_Z1_1 16 30676370 32486609 0.5169 0.9721 2.1362 1.7872 2 2WCM162_Z1_1 16 32487093 65345363 −0.6717 −0.4394 1.0733 0.4015 1 0WCM162_Z1_1 16 65388168 67469632 0.0913 0.49 NA NA NA NA WCM162_Z1_1 1667469743 70891771 −0.6251 −0.3792 1.0189 0.5188 1 1 WCM162_Z1_1 1670894091 82753020 −1.0308 −0.9253 1.0481 0.0051 1 0 WCM162_Z1_1 1682882290 88502998 −0.5918 −0.3365 1.5667 0.0172 2 0 WCM162_Z1_1 1688503329 89846290 −0.3089 0.0159 1.9944 0.0278 2 0 WCM162_Z1_1 1689849480 90162178 −0.766 −0.5629 1.2094 0.1444 1 0 WCM162_Z1_1 17 1315951972084 0.103 0.5035 1.8695 0.9658 2 1 WCM162_Z1_1 17 1985124 3819002−0.2341 0.1064 1.1763 0.9768 1 1 WCM162_Z1_1 17 3819168 4356375 0.05670.4499 NA NA NA NA WCM162_Z1_1 17 4381887 6014100 0.5087 0.963 2.02751.8713 2 2 WCM162_Z1_1 17 6021386 7462969 0.208 0.6241 2.1382 0.9444 2 1WCM162_Z1_1 17 7463436 7942885 −0.347 −0.0307 NA NA NA NA WCM162_Z1_1 177943298 9460842 0.1928 0.6067 1.9897 1.0559 2 1 WCM162_Z1_1 17 947178711696868 0.593 1.0565 2.1672 1.9924 2 2 WCM162_Z1_1 17 11700955 135043850.1643 0.5741 NA NA NA NA WCM162_Z1_1 17 13972942 16734869 −0.31440.0091 NA NA NA NA WCM162_Z1_1 17 16735618 19470414 0.2002 0.6152 2.00981.0537 2 1 WCM162_Z1_1 17 19474794 20483901 0.7011 1.1756 NA NA NA NAWCM162_Z1_1 17 20769980 22023445 0.182 0.5944 1.9318 1.0879 2 1WCM162_Z1_1 17 25620970 26857856 −0.2826 0.0479 NA NA NA NA WCM162_Z1_117 26861499 29151658 0.2917 0.7194 2.863 0.4298 3 0 WCM162_Z1_1 1729159404 30806364 −0.4765 −0.1909 1.8073 −0.0552 2 0 WCM162_Z1_1 1730806881 37459872 −1.0681 −0.9784 1.0012 0.0139 1 0 WCM162_Z1_1 1737499447 39114868 −0.3166 0.0066 2.0364 −0.0273 2 0 WCM162_Z1_1 1739240560 41833047 −1.014 −0.9015 1.0229 0.0477 1 0 WCM162_Z1_1 1741836085 44109474 −0.2645 0.0698 2.08 0.0191 2 0 WCM162_Z1_1 17 4411054745664643 0.3044 0.7337 NA NA NA NA WCM162_Z1_1 17 45677059 480723280.8424 1.3298 3.8721 1.1553 4 1 WCM162_Z1_1 17 48133856 49062302 0.48290.9343 2.8484 0.9736 3 1 WCM162_Z1_1 17 49063084 54588471 0.1743 0.5856NA NA NA NA WCM162_Z1_1 17 54671811 57125157 −0.3102 0.0143 1.05910.9608 1 1 WCM162_Z1_1 17 57126560 57643129 0.5815 1.0437 NA NA NA NAWCM162_Z1_1 17 57643990 59479161 0.9473 1.4435 NA NA NA NA WCM162_Z1_117 59480428 60140618 0.5302 0.9869 NA NA NA NA WCM162_Z1_1 17 6034452471746508 −0.2884 0.0408 1.0723 0.985 1 1 WCM162_Z1_1 17 7174679672763086 0.3196 0.7509 1.8674 1.4983 2 1 WCM162_Z1_1 17 7276429273502730 1.4192 1.9476 NA NA NA NA WCM162_Z1_1 17 73503170 745335120.2864 0.7133 1.9371 1.3421 2 1 WCM162_Z1_1 17 74534583 76045484 −0.31160.0125 NA NA NA NA WCM162_Z1_1 17 76045691 78039924 0.1683 0.5787 1.98511.0018 2 1 WCM162_Z1_1 17 78041446 80121181 0.5311 0.9879 2.6023 1.36433 1 WCM162_Z1_1 17 80129716 81083455 −0.1698 0.1835 NA NA NA NAWCM162_Z1_1 18 48272 11868541 0.0822 0.4795 1.7977 0.9908 2 1WCM162_Z1_1 18 11872280 15005663 −0.276 0.0559 NA NA NA NA WCM162_Z1_118 15006027 19994791 0.3311 0.7639 NA NA NA NA WCM162_Z1_1 18 1999575358310796 −0.2857 0.0441 1.0511 1.011 1 1 WCM162_Z1_1 18 5915784065181659 0.2709 0.6958 2.2158 1.0239 2 1 WCM162_Z1_1 18 6634434278005205 −0.2614 0.0735 1.1069 0.9976 1 1 WCM162_Z1_1 19 281395 375957−0.4262 −0.1282 NA NA NA NA WCM162_Z1_1 19 407260 619583 0.5488 1.0075NA NA NA NA WCM162_Z1_1 19 620073 1085910 0.91 1.4032 3.4755 1.8142 3 2WCM162_Z1_1 19 1085959 2280919 0.5475 1.006 2.0084 2.0084 2 2WCM162_Z1_1 19 2290147 3282486 0.1749 0.5863 1.9712 1.0316 2 1WCM162_Z1_1 19 3284943 8520452 −0.2756 0.0563 1.0637 1.0159 1 1WCM162_Z1_1 19 8527426 11200257 0.0218 0.4094 1.6252 1.031 2 1WCM162_Z1_1 19 11201363 13249139 −0.223 0.1198 1.1963 0.9769 1 1WCM162_Z1_1 19 13249222 13616825 −0.0255 0.3541 NA NA NA NA WCM162_Z1_119 13862624 15852274 0.1982 0.6129 1.9613 1.0974 2 1 WCM162_Z1_1 1915852700 17581460 −0.0205 0.36 1.5134 1.0535 2 1 WCM162_Z1_1 19 1759746519681514 −0.3342 −0.015 1.0163 0.963 1 1 WCM162_Z1_1 19 1972937120045557 0.2134 0.6303 NA NA NA NA WCM162_Z1_1 19 20117046 33882375−0.2918 0.0367 1.1204 0.9311 1 1 WCM162_Z1_1 19 33892633 35435069 0.27560.7011 2.0722 1.1792 2 1 WCM162_Z1_1 19 35435411 42937971 −0.3171 0.00591.0212 0.987 1 1 WCM162_Z1_1 19 42946932 45404313 0.1574 0.5662 1.97870.9825 2 1 WCM162_Z1_1 19 45404557 56321295 −0.3439 −0.0268 1.00560.9576 1 1 WCM162_Z1_1 19 56321475 58565377 0.1592 0.5682 1.9423 1.02312 1 WCM162_Z1_1 19 58570636 59083970 −0.2656 0.0684 1.1119 0.9851 1 1WCM162_Z1_1 2 41623 1947007 −0.0151 0.3663 NA NA NA NA WCM162_Z1_1 21982995 9419497 0.1451 0.552 1.9145 1.0178 2 1 WCM162_Z1_1 2 943747611053865 0.572 1.0332 2.2052 1.888 2 2 WCM162_Z1_1 2 11053945 117166370.2521 0.6744 NA NA NA NA WCM162_Z1_1 2 11718535 25326630 −0.2285 0.11311.1258 1.0373 1 1 WCM162_Z1_1 2 25344644 26846282 0.1461 0.5532 1.94140.9934 2 1 WCM162_Z1_1 2 26852310 29449819 −0.2924 0.0359 1.06 0.9903 11 WCM162_Z1_1 2 29450510 32903986 0.2348 0.6548 2.1484 1.0003 2 1WCM162_Z1_1 2 32927963 51255400 −0.2956 0.032 1.0522 0.9926 1 1WCM162_Z1_1 2 52929680 65659100 0.4378 0.8839 2.3243 1.3663 2 1WCM162_Z1_1 2 66585456 69771640 −0.3528 −0.0378 1.0685 0.8799 1 1WCM162_Z1_1 2 69784031 72786626 −0.0359 0.3419 NA NA NA NA WCM162_Z1_1 272802713 86712133 −0.3085 0.0164 1.0299 0.993 1 1 WCM162_Z1_1 2 8671296998916552 −0.0479 0.3278 1.5338 0.9764 2 1 WCM162_Z1_1 2 98920194105472888 −0.2752 0.0568 1.1321 0.9482 1 1 WCM162_Z1_1 2 105473048112989489 0.2657 0.6898 2.2014 1.0248 2 1 WCM162_Z1_1 2 112990918128631706 −0.3119 0.0122 1.0428 0.9741 1 1 WCM162_Z1_1 2 128699703131904331 0.4653 0.9146 NA NA NA NA WCM162_Z1_1 2 132110593 138208584−0.334 −0.0148 1.1761 0.8036 1 1 WCM162_Z1_1 2 138320856 1445255930.6049 1.0696 NA NA NA NA WCM162_Z1_1 2 144704689 153032137 0.08860.4869 NA NA NA NA WCM162_Z1_1 2 153192232 160053169 −0.3004 0.0262 NANA NA NA WCM162_Z1_1 2 160055512 163693049 0.1702 0.5809 2.0532 0.9383 21 WCM162_Z1_1 2 163695026 169439498 −0.2982 0.0289 1.1615 0.8789 1 1WCM162_Z1_1 2 169551479 171191900 0.1532 0.5614 1.952 0.9993 2 1WCM162_Z1_1 2 171225777 172600665 −0.3036 0.0224 NA NA NA NA WCM162_Z1_12 172602363 177036268 0.1953 0.6096 NA NA NA NA WCM162_Z1_1 2 177036754185803255 −0.2889 0.0402 1.0619 0.9946 1 1 WCM162_Z1_1 2 185803364193059154 0.2926 0.7204 1.9893 1.3059 2 1 WCM162_Z1_1 2 196544809202900999 −0.2715 0.0613 1.0889 0.9979 1 1 WCM162_Z1_1 2 202938424207176130 0.2074 0.6235 1.9595 1.1217 2 1 WCM162_Z1_1 2 207310075216300469 −0.2635 0.0709 1.0605 1.0402 1 1 WCM162_Z1_1 2 216808165219554646 0.52 0.9755 3.1468 0.786 3 1 WCM162_Z1_1 2 219555262 2199428990.143 0.5497 NA NA NA NA WCM162_Z1_1 2 219960006 224463141 −0.28920.0398 1.0878 0.9681 1 1 WCM162_Z1_1 2 224463170 227729815 0.2156 0.6329NA NA NA NA WCM162_Z1_1 2 227731974 231775627 −0.2767 0.055 1.07531.0023 1 1 WCM162_Z1_1 2 231861173 235405221 0.1069 0.508 1.8801 0.96412 1 WCM162_Z1_1 2 235943655 236403422 0.6049 1.0696 NA NA NA NAWCM162_Z1_1 2 236578807 242946597 −0.3319 −0.0122 1.011 0.9722 1 1WCM162_Z1_1 20 68351 6759629 −0.3099 0.0147 1.0373 0.9832 1 1WCM162_Z1_1 20 6759706 14308144 0.5524 1.0115 3.0868 0.9452 3 1WCM162_Z1_1 20 14665558 46318901 −0.3137 0.0101 1.0438 0.9702 1 1WCM162_Z1_1 20 46331321 53266980 0.2209 0.6388 2.1078 1.0063 2 1WCM162_Z1_1 20 54573624 55748206 −0.4216 −0.1225 0.9652 0.8719 1 1WCM162_Z1_1 20 55750050 55966818 0.2472 0.6688 NA NA NA NA WCM162_Z1_120 55967778 57617770 0.6704 1.1418 2.3158 2.0974 2 2 WCM162_Z1_1 2057766230 60791797 0.2469 0.6685 NA NA NA NA WCM162_Z1_1 20 6079186662904863 −0.3041 0.0217 1.0485 0.9818 1 1 WCM162_Z1_1 21 982620517250200 −0.3243 −0.0029 1.0832 0.9127 1 1 WCM162_Z1_1 21 1725073730464055 0.0521 0.4446 1.7355 0.9864 2 1 WCM162_Z1_1 21 3046478636079575 −0.3262 −0.0052 1.0426 0.9502 1 1 WCM162_Z1_1 21 3608036638132035 0.1622 0.5717 2.0662 0.9063 2 1 WCM162_Z1_1 21 3813747045064211 −0.2799 0.051 1.0561 1.0159 1 1 WCM162_Z1_1 21 4507652847320528 0.1827 0.5951 NA NA NA NA WCM162_Z1_1 21 47320949 48084281−0.32 0.0023 1.0553 0.9479 1 1 WCM162_Z1_1 22 16287495 17671149 0.24020.6609 NA NA NA NA WCM162_Z1_1 22 17672662 21414708 0.5067 0.9607 2.80611.0864 3 1 WCM162_Z1_1 22 21576156 24237463 0.1839 0.5966 2.0437 0.98052 1 WCM162_Z1_1 22 24237682 40859227 −0.2959 0.0317 1.0458 0.9986 1 1WCM162_Z1_1 22 41075635 41625569 0.1474 0.5547 NA NA NA NA WCM162_Z1_122 41626190 43089470 0.5277 0.9841 2.0968 1.8595 2 2 WCM162_Z1_1 2243089849 44028074 0.1457 0.5528 1.9357 0.9981 2 1 WCM162_Z1_1 2244031058 46449730 −0.298 0.0291 1.0477 0.9931 1 1 WCM162_Z1_1 2246449893 48940506 0.1834 0.596 1.9581 1.0649 2 1 WCM162_Z1_1 22 4894235351215137 −0.2861 0.0435 1.0619 0.9994 1 1 WCM162_Z1_1 3 239347 3888402−0.364 −0.0515 NA NA NA NA WCM162_Z1_1 3 4110270 7649764 0.2887 0.716 NANA NA NA WCM162_Z1_1 3 7721939 9945733 −0.3554 −0.0409 1.0018 0.9422 1 1WCM162_Z1_1 3 9948050 11350521 0.166 0.5761 1.9731 1.0085 2 1WCM162_Z1_1 3 11354843 13399786 0.5632 1.0235 3.0058 1.0598 3 1WCM162_Z1_1 3 13401875 13671430 0.2249 0.6434 NA NA NA NA WCM162_Z1_1 313672256 15269462 −0.3085 0.0164 NA NA NA NA WCM162_Z1_1 3 1527056618390752 0.2117 0.6284 NA NA NA NA WCM162_Z1_1 3 18391160 36873819−0.2392 0.1002 1.2205 0.9234 1 1 WCM162_Z1_1 3 36874135 38042425 0.18710.6002 NA NA NA NA WCM162_Z1_1 3 38042993 40574559 0.4503 0.8979 1.95711.7696 2 2 WCM162_Z1_1 3 41265567 41723263 0.132 0.537 NA NA NA NAWCM162_Z1_1 3 41746628 47870597 −0.3084 0.0165 1.0226 1.0004 1 1WCM162_Z1_1 3 47882580 47894745 0.6337 1.1014 NA NA NA NA WCM162_Z1_1 347896774 48573754 0.4302 0.8754 NA NA NA NA WCM162_Z1_1 3 4857593049570882 0.725 1.2018 2.6983 1.9021 3 2 WCM162_Z1_1 3 49662635 498454710.176 0.5875 NA NA NA NA WCM162_Z1_1 3 49845842 51317578 −0.2968 0.0306NA NA NA NA WCM162_Z1_1 3 51347686 53920940 0.1716 0.5825 1.9369 1.05792 1 WCM162_Z1_1 3 53922508 63661228 −0.2687 0.0646 1.0736 1.018 1 1WCM162_Z1_1 3 63805214 67275920 0.4115 0.8545 NA NA NA NA WCM162_Z1_1 367411103 112299732 −0.2778 0.0537 1.0668 1.009 1 1 WCM162_Z1_1 3112300090 119373355 0.15 0.5576 1.9235 1.0203 2 1 WCM162_Z1_1 3119378872 121563395 −0.3089 0.0158 NA NA NA NA WCM162_Z1_1 3 121573628133907702 0.1914 0.6051 2.045 0.9972 2 1 WCM162_Z1_1 3 133910803143704616 −0.2864 0.0433 1.0579 1.0029 1 1 WCM162_Z1_1 3 143708352148757885 0.4423 0.8889 NA NA NA NA WCM162_Z1_1 3 148759439 167351216−0.2082 0.1375 1.1383 1.0617 1 1 WCM162_Z1_1 3 167371084 167543112 0.5491.0078 NA NA NA NA WCM162_Z1_1 3 167728070 169381124 −0.2983 0.0288 NANA NA NA WCM162_Z1_1 3 169482658 174577202 0.2278 0.6468 NA NA NA NAWCM162_Z1_1 3 174814784 180650188 −0.2996 0.0272 NA NA NA NA WCM162_Z1_13 180651130 183967556 0.3137 0.7442 1.7982 1.5519 2 2 WCM162_Z1_1 3183975460 189038499 −0.3226 −8.00E−04 1.0628 0.9361 1 1 WCM162_Z1_1 3189349353 190374214 0.2442 0.6654 NA NA NA NA WCM162_Z1_1 3 190573229194408362 −0.3057 0.0198 1.0977 0.9299 1 1 WCM162_Z1_1 3 194408704197238772 0.2035 0.619 2.0939 0.9776 2 1 WCM162_Z1_1 3 197239101197894726 −0.3555 −0.041 NA NA NA NA WCM162_Z1_1 4 59404 3221934 0.19960.6145 2.1437 0.9183 2 1 WCM162_Z1_1 4 3224184 15003656 −0.2973 0.031.0557 0.9863 1 1 WCM162_Z1_1 4 15003936 17666205 0.527 0.9834 2.98750.9667 3 1 WCM162_Z1_1 4 17690076 24914486 −0.1077 0.2573 NA NA NA NAWCM162_Z1_1 4 25001439 27162478 0.4224 0.8666 NA NA NA NA WCM162_Z1_1 428364214 37828373 −0.3387 −0.0204 NA NA NA NA WCM162_Z1_1 4 3783165841699194 0.2809 0.7071 2.1585 1.1066 2 1 WCM162_Z1_1 4 41747853 46263926−0.3201 0.0023 NA NA NA NA WCM162_Z1_1 4 46305495 48583588 0.2117 0.62842.0278 1.0639 2 1 WCM162_Z1_1 4 48588742 56225539 −0.3261 −0.0051 NA NANA NA WCM162_Z1_1 4 56230378 70361342 0.1453 0.5523 2.0042 0.9286 2 1WCM162_Z1_1 4 70361543 73149405 −0.2755 0.0564 NA NA NA NA WCM162_Z1_1 473154498 75971423 0.5552 1.0147 NA NA NA NA WCM162_Z1_1 4 76407839105412771 −0.283 0.0473 1.0709 0.9957 1 1 WCM162_Z1_1 4 106155296109461954 0.1525 0.5605 NA NA NA NA WCM162_Z1_1 4 109478108 110460786−0.6213 −0.3743 NA NA NA NA WCM162_Z1_1 4 110580185 113540768 0.26880.6934 2.6236 0.6107 3 1 WCM162_Z1_1 4 113541183 113825648 0.0058 0.3907NA NA NA NA WCM162_Z1_1 4 113970897 119256710 −0.66 −0.4243 NA NA NA NAWCM162_Z1_1 4 119259449 143044460 −0.1713 0.1817 1.4063 0.8621 1 1WCM162_Z1_1 4 143045817 149358014 0.4273 0.8721 2.0189 1.6417 2 2WCM162_Z1_1 4 151000419 165118755 −0.304 0.0219 1.0486 0.9819 1 1WCM162_Z1_1 4 165878405 166795069 0.2193 0.6371 NA NA NA NA WCM162_Z1_14 166910635 171010772 0.8043 1.2884 NA NA NA NA WCM162_Z1_1 4 172735808175604041 0.2319 0.6514 NA NA NA NA WCM162_Z1_1 4 175636717 186997882−0.2852 0.0447 1.0678 0.9952 1 1 WCM162_Z1_1 4 186998098 1904265020.1916 0.6054 NA NA NA NA WCM162_Z1_1 5 140443 796297 −0.281 0.04971.0702 0.9999 1 1 WCM162_Z1_1 5 814886 32786413 −0.0347 0.3432 1.52611.0112 2 1 WCM162_Z1_1 5 32789694 36208784 0.3328 0.7658 1.804 1.5967 22 WCM162_Z1_1 5 36211967 53751988 −0.0331 0.3452 1.5743 0.9664 2 1WCM162_Z1_1 5 53814062 63894249 −0.3376 −0.0191 1.0544 0.9193 1 1WCM162_Z1_1 5 63905079 65474605 0.1869 0.6 NA NA NA NA WCM162_Z1_1 565892597 96519230 −0.2708 0.0621 1.0642 1.0237 1 1 WCM162_Z1_1 598109828 108436193 −1.0375 −0.9348 NA NA NA NA WCM162_Z1_1 5 108516527109106104 −0.0906 0.2775 NA NA NA NA WCM162_Z1_1 5 109110537 1148613040.7098 1.1851 2.4408 2.1067 2 2 WCM162_Z1_1 5 114878759 118507544−0.3229 −0.0012 NA NA NA NA WCM162_Z1_1 5 118510994 124080614 0.18020.5924 1.6476 1.3678 2 1 WCM162_Z1_1 5 125696025 135416296 −0.25560.0805 1.074 1.0408 1 1 WCM162_Z1_1 5 135469500 137904647 0.7671 1.2478NA NA NA NA WCM162_Z1_1 5 137906805 140774636 −0.3272 −0.0065 1.02710.9639 1 1 WCM162_Z1_1 5 140778259 143059433 0.1918 0.6057 2.0371 1.00632 1 WCM162_Z1_1 5 143191860 147863825 −0.1818 0.1692 1.1957 1.0532 1 1WCM162_Z1_1 5 147870374 150257594 0.144 0.5508 1.9685 0.9612 2 1WCM162_Z1_1 5 150275138 156945875 −0.2524 0.0844 1.1165 1.0039 1 1WCM162_Z1_1 5 156946942 173035285 0.1228 0.5264 1.5897 1.291 2 1WCM162_Z1_1 5 173036261 180687773 −0.3221 −2.00E−04 1.0291 0.9706 1 1WCM162_Z1_1 6 203552 22146924 −0.2956 0.0321 1.0461 0.9989 1 1WCM162_Z1_1 6 22147408 25450202 0.1573 0.5661 1.9871 0.9739 2 1WCM162_Z1_1 6 25450617 33235641 −0.3229 −0.0012 1.0138 0.9846 1 1WCM162_Z1_1 6 33235755 35200740 0.0166 0.4033 1.4536 1.1914 1 1WCM162_Z1_1 6 35200985 40998158 −0.2904 0.0384 1.0706 0.9833 1 1WCM162_Z1_1 6 40998395 41310669 0.1572 0.5659 NA NA NA NA WCM162_Z1_1 641318438 44272221 0.8001 1.2838 3.1037 1.766 3 2 WCM162_Z1_1 6 4427250346216493 0.4206 0.8646 NA NA NA NA WCM162_Z1_1 6 46293210 62887088−0.2873 0.0421 1.0496 1.0096 1 1 WCM162_Z1_1 6 62995834 65525121 0.24660.6681 2.052 1.126 2 1 WCM162_Z1_1 6 65531555 73516585 −0.2321 0.10881.1198 1.0368 1 1 WCM162_Z1_1 6 73677432 84930814 0.2023 0.6177 2.00971.0591 2 1 WCM162_Z1_1 6 84936092 99282761 −0.2944 0.0335 1.103 0.9439 11 WCM162_Z1_1 6 99283328 101315842 0.91 1.4032 NA NA NA NA WCM162_Z1_1 6101847171 131277564 −0.2342 0.1063 1.1037 1.0492 1 1 WCM162_Z1_1 6131466515 135507079 0.1662 0.5763 1.9152 1.0668 2 1 WCM162_Z1_1 6135509024 138833430 0.8363 1.3233 2.8616 2.143 3 2 WCM162_Z1_1 6138892979 149395233 −0.0586 0.3152 1.3862 1.1022 1 1 WCM162_Z1_1 6149691202 152489038 0.4733 0.9235 2.4321 1.3613 2 1 WCM162_Z1_1 6152489294 153332747 0.0293 0.4181 NA NA NA NA WCM162_Z1_1 6 153344530156275691 −0.3049 0.0208 NA NA NA NA WCM162_Z1_1 6 157099205 1593162760.2594 0.6828 NA NA NA NA WCM162_Z1_1 6 159331220 170893435 −0.29720.0301 1.1402 0.902 1 1 WCM162_Z1_1 7 193265 3205705 −0.2657 0.06831.0865 1.0105 1 1 WCM162_Z1_1 7 3658806 5460136 0.2112 0.6278 2.00931.0811 2 1 WCM162_Z1_1 7 5460239 6205440 −0.2285 0.1132 NA NA NA NAWCM162_Z1_1 7 6210248 8791392 0.3356 0.769 1.7811 1.6272 2 2 WCM162_Z1_17 10973282 14249142 −0.3139 0.0098 1.1147 0.8989 1 1 WCM162_Z1_1 714378237 16921571 0.2096 0.6259 NA NA NA NA WCM162_Z1_1 7 1733890018535851 −0.3431 −0.0258 NA NA NA NA WCM162_Z1_1 7 18617811 280602550.2403 0.6609 1.8908 1.2714 2 1 WCM162_Z1_1 7 28111248 31003690 0.75831.2382 2.7097 2.0083 3 2 WCM162_Z1_1 7 31008552 42079796 0.3387 0.77252.4042 1.0123 2 1 WCM162_Z1_1 7 42085094 44807194 0.7169 1.1929 3.55651.0158 4 1 WCM162_Z1_1 7 44838852 56022658 0.1769 0.5886 1.9656 1.0419 21 WCM162_Z1_1 7 56022865 65233274 −0.2737 0.0586 1.2886 0.7943 1 1WCM162_Z1_1 7 65305416 72892707 0.5846 1.0472 NA NA NA NA WCM162_Z1_1 772966569 77045605 0.095 0.4943 1.9654 0.8518 2 1 WCM162_Z1_1 7 7716695879082370 0.7867 1.2691 NA NA NA NA WCM162_Z1_1 7 79082596 92354972−0.2593 0.076 1.2451 0.8631 1 1 WCM162_Z1_1 7 92404097 95053889 0.21940.6371 NA NA NA NA WCM162_Z1_1 7 95115426 96650360 −0.1711 0.1819 NA NANA NA WCM162_Z1_1 7 96651501 100091311 0.9506 1.4471 4.2763 1.177 4 1WCM162_Z1_1 7 100137121 102881051 −0.3369 −0.0183 1.1455 0.8293 1 1WCM162_Z1_1 7 102895234 103290786 0.0594 0.4531 NA NA NA NA WCM162_Z1_17 103292176 108206300 −0.2792 0.0519 1.0894 0.9839 1 1 WCM162_Z1_1 7108209988 116199331 0.125 0.5289 NA NA NA NA WCM162_Z1_1 7 116339224122091469 0.4765 0.9271 NA NA NA NA WCM162_Z1_1 7 122111493 133261429−0.0308 0.3479 1.4756 1.0697 1 1 WCM162_Z1_1 7 133314861 1351230670.7029 1.1775 2.8822 1.6415 3 2 WCM162_Z1_1 7 135255995 137172383−0.0408 0.3361 NA NA NA NA WCM162_Z1_1 7 137178573 139226819 0.62291.0895 3.1726 1.0833 3 1 WCM162_Z1_1 7 139229024 142334894 0.1031 0.50361.7223 1.1132 2 1 WCM162_Z1_1 7 142353505 144708009 0.9873 1.4868 4.58271.0226 5 1 WCM162_Z1_1 7 145601241 150020619 0.2032 0.6186 1.6477 1.42312 1 WCM162_Z1_1 7 150027559 152142849 0.6283 1.0954 3.2583 1.0152 3 1WCM162_Z1_1 7 152143261 158937375 0.2809 0.7072 1.79 1.4752 2 1WCM162_Z1_1 8 190897 4851916 −1.049 −0.9511 1.0337 8.00E−04 1 0WCM162_Z1_1 8 6266812 7215653 −0.3288 −0.0084 NA NA NA NA WCM162_Z1_1 87215836 12004001 −1.0674 −0.9775 1.0236 −0.0078 1 0 WCM162_Z1_1 812042922 20112642 −0.323 −0.0013 2.013 −0.0148 2 0 WCM162_Z1_1 821550826 29953045 −1.0569 −0.9624 0.9836 0.0428 1 0 WCM162_Z1_1 829953401 55576321 −0.2508 0.0863 1.1052 1.0181 1 1 WCM162_Z1_1 855586412 59872515 0.1602 0.5695 NA NA NA NA WCM162_Z1_1 8 6003152868972954 −0.3193 0.0032 1.0401 0.9643 1 1 WCM162_Z1_1 8 6898135969728143 0.2525 0.6749 NA NA NA NA WCM162_Z1_1 8 69730480 729486720.9511 1.4476 NA NA NA NA WCM162_Z1_1 8 72950215 75171708 0.367 0.80442.5348 0.9581 3 1 WCM162_Z1_1 8 75227143 101937169 −0.2295 0.112 1.161.0014 1 1 WCM162_Z1_1 8 101960329 109009148 0.1869 0.6 1.9964 1.0351 21 WCM162_Z1_1 8 109094770 118817117 0.6136 1.0792 3.1694 1.0563 3 1WCM162_Z1_1 8 118819560 124801970 0.2699 0.6946 2.1845 1.0523 2 1WCM162_Z1_1 8 124810427 131955674 −0.23 0.1114 1.1777 0.9828 1 1WCM162_Z1_1 8 131964193 144650032 0.2147 0.6317 2.0394 1.0594 2 1WCM162_Z1_1 8 144650375 145732358 0.8379 1.325 3.7506 1.2601 4 1WCM162_Z1_1 8 145734792 146076708 0.2959 0.7242 2.2677 1.0362 2 1WCM162_Z1_1 8 146105825 146279527 −0.3454 −0.0287 NA NA NA NAWCM162_Z1_1 9 17074 710966 0.1815 0.5939 2.0763 0.9422 2 1 WCM162_Z1_1 9711396 3228871 0.4978 0.9509 2.0751 1.791 2 2 WCM162_Z1_1 9 32480258528711 0.1979 0.6126 2.0465 1.0114 2 1 WCM162_Z1_1 9 8633445 151777780.8652 1.3547 4.2151 0.8996 4 1 WCM162_Z1_1 9 15182370 18950787 0.34860.7837 NA NA NA NA WCM162_Z1_1 9 19032906 20789594 0.8222 1.3079 NA NANA NA WCM162_Z1_1 9 20819849 23765050 0.2489 0.6708 NA NA NA NAWCM162_Z1_1 9 24543256 26116168 1.2384 1.7558 NA NA NA NA WCM162_Z1_1 926842384 35562430 0.4123 0.8553 2.4258 1.1924 2 1 WCM162_Z1_1 9 3556289537955953 0.7734 1.2547 2.579 2.1934 3 2 WCM162_Z1_1 9 37974743 384242450.5624 1.0226 NA NA NA NA WCM162_Z1_1 9 38527117 71866216 0.1232 0.52681.7628 1.1187 2 1 WCM162_Z1_1 9 71867751 75407265 0.6589 1.1292 NA NA NANA WCM162_Z1_1 9 75420379 82006446 −0.0836 0.2858 1.278 1.1601 1 1WCM162_Z1_1 9 82006548 85677674 0.3613 0.798 NA NA NA NA WCM162_Z1_1 985863188 88457757 −0.3136 0.0101 NA NA NA NA WCM162_Z1_1 9 8846428694519715 0.3263 0.7585 2.2842 1.0992 2 1 WCM162_Z1_1 9 94519838 954757441.1311 1.6412 NA NA NA NA WCM162_Z1_1 9 95477468 97369228 0.3514 0.7869NA NA NA NA WCM162_Z1_1 9 97372256 100105735 −0.2846 0.0453 NA NA NA NAWCM162_Z1_1 9 100107898 102068867 0.4688 0.9186 2.4578 1.3227 2 1WCM162_Z1_1 9 102589053 123870111 −0.2547 0.0816 1.085 1.0314 1 1WCM162_Z1_1 9 123874854 130191186 0.3557 0.7917 2.2812 1.181 2 1WCM162_Z1_1 9 130197414 130825931 0.5986 1.0626 NA NA NA NA WCM162_Z1_19 130826167 131900037 0.2841 0.7108 2.1991 1.0743 2 1 WCM162_Z1_1 9131904750 141111414 −0.2955 0.0322 1.1058 0.9393 1 1 WCM162_Z1_1 X2700156 31341744 −0.2953 0.0324 NA NA NA NA WCM162_Z1_1 X 3136674631986543 −2.005 −2.6414 NA NA NA NA WCM162_Z1_1 X 32235149 43741497−0.2948 0.033 NA NA NA NA WCM162_Z1_1 X 43809119 46696611 0.6992 1.1735NA NA NA NA WCM162_Z1_1 X 46713261 49075803 1.6762 2.218 NA NA NA NAWCM162_Z1_1 X 49079035 55650231 0.8533 1.3417 NA NA NA NA WCM162_Z1_1 X55650703 78622653 −0.3147 0.0088 NA NA NA NA WCM162_Z1_1 X 7927794080552709 0.8131 1.2979 NA NA NA NA WCM162_Z1_1 X 82763411 86071084−0.3818 −0.0733 NA NA NA NA WCM162_Z1_1 X 86773300 100613625 0.07010.4654 NA NA NA NA WCM162_Z1_1 X 100614336 123234423 −0.3579 −0.0439 NANA NA NA WCM162_Z1_1 X 123480504 125955487 0.454 0.902 NA NA NA NAWCM162_Z1_1 X 127185439 132548850 −0.3572 −0.0431 NA NA NA NAWCM162_Z1_1 X 132670164 134715513 0.5139 0.9688 NA NA NA NA WCM162_Z1_1X 134989113 154509348 −0.3094 0.0152 NA NA NA NA WCM162_Z9_1 1 69594249212550 0.0059 NA NA NA NA NA WCM162_Z9_1 10 225960 135440080 0.0115NA NA NA NA NA WCM162_Z9_1 11 130546 134856523 −0.0072 NA NA NA NA NAWCM162_Z9_1 12 148674 133810712 0.0351 NA NA NA NA NA WCM162_Z9_1 1319600364 115089411 0.0068 NA NA NA NA NA WCM162_Z9_1 14 19377737107283019 0.0137 NA NA NA NA NA WCM162_Z9_1 15 20170133 102517678−0.0018 NA NA NA NA NA WCM162_Z9_1 16 66953 3824584 −0.0344 NA NA NA NANA WCM162_Z9_1 16 3828064 33961794 0.0491 NA NA NA NA NA WCM162_Z9_1 1633962238 90162177 −0.042 NA NA NA NA NA WCM162_Z9_1 17 131595 295854400.0282 NA NA NA NA NA WCM162_Z9_1 17 29587440 41958701 −0.0912 NA NA NANA NA WCM162_Z9_1 17 41958941 72709000 0.0337 NA NA NA NA NA WCM162_Z9_117 72725434 73494805 0.3207 NA NA NA NA NA WCM162_Z9_1 17 7349516281083455 0.0014 NA NA NA NA NA WCM162_Z9_1 18 48221 78005199 −0.018 NANA NA NA NA WCM162_Z9_1 19 281413 59083985 −0.0305 NA NA NA NA NAWCM162_Z9_1 2 41614 242946604 0.0262 NA NA NA NA NA WCM162_Z9_1 20 6837362904835 −0.0109 NA NA NA NA NA WCM162_Z9_1 21 9826207 48084226 −0.0156NA NA NA NA NA WCM162_Z9_1 22 16287497 51215123 −0.0126 NA NA NA NA NAWCM162_Z9_1 3 239347 197894720 0.0164 NA NA NA NA NA WCM162_Z9_1 4 59408190426502 0.0304 NA NA NA NA NA WCM162_Z9_1 5 140663 180687803 0.0119 NANA NA NA NA WCM162_Z9_1 6 203552 170893408 0.0093 NA NA NA NA NAWCM162_Z9_1 7 193253 158937400 0.0577 NA NA NA NA NA WCM162_Z9_1 8190907 139763703 −6.00E−04 NA NA NA NA NA WCM162_Z9_1 8 139767450146156846 0.168 NA NA NA NA NA WCM162_Z9_1 8 146157063 146279528 0.006NA NA NA NA NA WCM162_Z9_1 9 17056 328102 −0.2616 NA NA NA NA NAWCM162_Z9_1 9 332403 95608515 0.0992 NA NA NA NA NA WCM162_Z9_1 995608796 141111414 0.0011 NA NA NA NA NA WCM162_Z9_1 X 2700119 45059985−0.0831 NA NA NA NA NA WCM162_Z9_1 X 46322830 63410486 0.259 NA NA NA NANA WCM162_Z9_1 X 63410609 67273643 0.8022 NA NA NA NA NA WCM162_Z9_1 X67283750 67741339 0.119 NA NA NA NA NA WCM162_Z9_1 X 67742672 154509348−0.0596 NA NA NA NA NA WCM163 1 14907 3566483 0.0123 0.5873 1.77441.2303 2 1 WCM163 1 3598910 19666149 −0.435 0.0612 1.791 0.2957 2 0WCM163 1 19669362 20879690 0.067 0.6498 1.6315 1.5064 2 2 WCM163 120880587 23857025 −0.4016 0.1016 1.8536 0.2923 2 0 WCM163 1 2388436935447738 −0.0429 0.5238 1.7792 1.0964 2 1 WCM163 1 35449342 53736722−0.2013 0.3396 1.7747 0.7561 2 1 WCM163 1 53736989 142713878 −0.02290.5469 1.797 1.1249 2 1 WCM163 1 142727161 249213961 0.501 1.1354 2.47461.9189 2 2 WCM163 10 225920 32576111 −0.3522 0.1609 1.1233 1.1126 1 1WCM163 10 32580219 135477928 −0.0707 0.4918 1.5135 1.2989 2 1 WCM163 11193105 62297210 −0.0347 0.5333 1.7806 1.1139 2 1 WCM163 11 6229754865233864 −0.1497 0.4 1.6458 0.9933 2 1 WCM163 11 65265442 65293083−1.1962 −0.928 NA NA NA NA WCM163 11 65293528 67022750 −0.1661 0.38091.5015 1.1028 2 1 WCM163 11 67023037 134605916 −0.0296 0.5391 1.71741.1888 2 1 WCM163 12 148427 38364209 −0.5394 −0.0661 1.8691 0.0413 2 0WCM163 12 38596734 39998777 −0.1326 0.42 NA NA NA NA WCM163 12 4000148354719023 −0.2378 0.2968 1.6251 0.8317 2 1 WCM163 12 54731126 133810883−0.1111 0.445 1.5557 1.1669 2 1 WCM163 13 19042059 22178191 0.26620.8748 2.341 1.3266 2 1 WCM163 13 22202744 24334368 −0.618 −0.16341.3135 0.4724 1 0 WCM163 13 24334651 32849014 0.3807 1.0024 2.04781.9589 2 2 WCM163 13 32849172 44971311 −0.4337 0.0628 1.693 0.3961 2 0WCM163 13 45008046 48664499 −0.8988 −0.5225 0.9663 0.426 1 0 WCM163 1348667727 50140708 −1.8694 −2.013 0.3361 0.1594 0 0 WCM163 13 5014096251523661 −1.0341 −0.7033 NA NA NA NA WCM163 13 51528055 72012167 −0.5312−0.056 1.5384 0.3854 2 0 WCM163 13 72012603 96539554 0.1089 0.69751.6549 1.5886 2 2 WCM163 13 96540242 101256476 −0.1908 0.352 1.27641.2764 1 1 WCM163 13 101257253 115089411 0.1536 0.7481 1.6986 1.6606 2 2WCM163 14 19110338 51491970 0.2016 0.8022 1.7438 1.7438 2 2 WCM163 1451560857 71582083 0.0076 0.5818 1.7697 1.2239 2 1 WCM163 14 71996051107283270 0.2769 0.8867 1.849 1.849 2 2 WCM163 15 20083968 23114146−0.1674 0.3794 1.8648 0.7368 2 1 WCM163 15 23128382 59344625 −0.00920.5626 1.6482 1.3056 2 1 WCM163 15 59344672 102506240 −0.2043 0.33621.7084 0.8163 2 1 WCM163 16 64430 103575 −0.535 −0.0607 NA NA NA NAWCM163 16 103923 71319679 −0.0598 0.5044 1.4513 1.3857 1 1 WCM163 1671392787 90168687 −0.6674 −0.2251 1.651 0.06 2 0 WCM163 17 131595 463759−0.0487 0.5172 NA NA NA NA WCM163 17 463843 7478498 −0.3709 0.13841.1007 1.1007 1 1 WCM163 17 7480081 7960992 −0.7263 −0.2996 1.6402−0.0152 2 0 WCM163 17 7976291 81052551 0.0475 0.6275 1.7443 1.3456 2 1WCM163 18 47666 78005146 0.2038 0.8048 1.7469 1.7469 2 2 WCM163 19104935 30054822 0.125 0.7158 1.6424 1.6424 2 2 WCM163 19 3009420843699356 −0.2697 0.259 2.3409 0.0524 2 0 WCM163 19 43702293 43766263−1.9045 −2.0799 NA NA NA NA WCM163 19 43772124 54006848 −0.3115 0.20952.2816 0.0309 2 0 WCM163 19 54072622 59093696 0.3796 1.0012 2.03271.9705 2 2 WCM163 2 41662 96850652 −0.043 0.5238 1.4377 1.4377 1 1WCM163 2 96850885 96971102 −0.3593 0.1523 NA NA NA NA WCM163 2 96991492233470843 −0.1367 0.4151 1.4903 1.1766 1 1 WCM163 2 233498576 242690876−0.2234 0.3137 1.5529 0.9328 2 1 WCM163 2 242694601 243037013 −0.04410.5224 1.6252 1.2476 2 1 WCM163 20 68336 62959246 0.016 0.5915 1.68121.3324 2 1 WCM163 21 9590326 39906149 −0.0053 0.5671 1.6976 1.2655 2 1WCM163 21 39947601 42848578 −0.5563 −0.0869 1.8449 0.0382 2 0 WCM163 2142851197 48084149 0.0467 0.6267 1.6851 1.4029 2 1 WCM163 22 1615897325774702 −0.064 0.4995 1.6162 1.2112 2 1 WCM163 22 25777515 50870685−0.5582 −0.0893 1.0165 0.8635 1 1 WCM163 22 50873364 51223730 0.0510.6315 2.1789 0.9195 2 1 WCM163 3 239349 46784329 0.0175 0.5933 1.72471.2927 2 1 WCM163 3 46785355 52821011 −0.0884 0.4713 1.7204 1.0523 2 1WCM163 3 52821186 71161672 −0.0185 0.552 1.6936 1.2385 2 1 WCM163 371179844 75496082 −0.5217 −0.0443 1.9212 0.0183 2 0 WCM163 3 75599058101062749 0.0256 0.6025 1.7374 1.2994 2 1 WCM163 3 101066612 115342611−0.1257 0.428 1.7882 0.9025 2 1 WCM163 3 115350247 141682610 0.02460.6014 1.7777 1.2567 2 1 WCM163 3 141688904 160970552 −0.2444 0.2891.7608 0.6827 2 1 WCM163 3 161062777 192053227 −0.0258 0.5435 1.72751.1875 2 1 WCM163 3 192078416 197785570 −0.1981 0.3434 1.7941 0.7434 2 1WCM163 3 197785804 197896656 0.0263 0.6033 NA NA NA NA WCM163 4 5346952779488 −0.4711 0.0175 1.5418 0.4826 2 0 WCM163 4 52779778 90855914−0.2035 0.3371 1.4975 1.0289 1 1 WCM163 4 90856341 184647831 −0.07260.4896 1.7287 1.0793 2 1 WCM163 4 184827253 186298102 0.3807 1.00243.9816 0.025 4 0 WCM163 4 186299319 190903980 −0.3908 0.1146 2.10360.0618 2 0 WCM163 5 90680 50138236 0.0176 0.5934 1.6989 1.3187 2 1WCM163 5 50679150 148618941 −0.3623 0.1488 1.8192 0.3981 2 0 WCM163 5148619412 180687804 0.0587 0.6403 1.7721 1.3453 2 1 WCM163 6 20336410430494 −0.041 0.526 1.8017 1.0782 2 1 WCM163 6 10509342 315842230.3541 0.9729 1.9758 1.9496 2 2 WCM163 6 31584512 31829856  1.00E−040.5733 1.5801 1.3957 2 1 WCM163 6 31830485 47846043 0.2179 0.8207 1.76621.7662 2 2 WCM163 6 47846349 70890113 0.0763 0.6604 1.7804 1.3808 2 1WCM163 6 70890394 84563410 −0.0181 0.5524 1.5053 1.4277 2 1 WCM163 684563915 142487469 −0.2636 0.2663 1.2041 1.2013 1 1 WCM163 6 142490556167275697 0.0371 0.6157 1.809 1.2555 2 1 WCM163 6 167343104 170893464−0.2774 0.2499 1.2117 1.1666 1 1 WCM163 7 193346 87908854 −0.0517 0.51371.7011 1.1542 2 1 WCM163 7 87908918 129908822 −0.2153 0.3233 1.73650.7658 2 1 WCM163 7 129909527 131150990 −0.1831 0.361 1.5114 1.0572 2 1WCM163 7 131155668 144094425 0.0293 0.6067 1.7998 1.2458 2 1 WCM163 7144094600 158937135 −0.2131 0.3258 1.7394 0.7673 2 1 WCM163 8 16353648974169 −0.0426 0.5241 1.4497 1.4265 1 1 WCM163 8 49503215 631616600.1983 0.7986 1.7394 1.7394 2 2 WCM163 8 63195064 100865937 0.44371.0721 2.1397 2.0654 2 2 WCM163 8 100866202 145616288 0.2879 0.89912.2984 1.4313 2 1 WCM163 8 145616586 146279480 0.1178 0.7076 1.89431.3719 2 1 WCM163 9 15900 141107582 0.2001 0.8006 1.7418 1.7418 2 2WCM163 X 2700156 64254635 0.5579 1.1977 NA NA NA NA WCM163 X 6443518767333003 1.1805 1.868 NA NA NA NA WCM163 X 67339047 154509348 0.58981.2327 NA NA NA NA WCM163_Z7_1 1 69592 3566525 0.3303 0.9981 2.0371.9578 2 2 WCM163_Z7_1 1 3598963 8029446 −0.6118 −0.003 2.0112 −0.0154 20 WCM163_Z7_1 1 8031068 8482842 0.1934 0.855 NA NA NA NA WCM163_Z7_1 18525970 19655128 −0.5865 0.0244 2.0317 0.0025 2 0 WCM163_Z7_1 1 1966609420834410 0.2761 0.9415 NA NA NA NA WCM163_Z7_1 1 20879475 23857070−0.6031 0.0064 1.9856 0.0233 2 0 WCM163_Z7_1 1 23857285 34684351 0.33981.008 2.0321 1.9902 2 2 WCM163_Z7_1 1 35135208 46775884 −0.6139 −0.00532.0016 −0.009 2 0 WCM163_Z7_1 1 46782226 47025935 0.2573 0.9218 NA NA NANA WCM163_Z7_1 1 47027285 53793521 −0.611 −0.0021 2.0015 −0.0045 2 0WCM163_Z7_1 1 53925247 64680553 0.3529 1.0217 2.0493 2.0112 2 2WCM163_Z7_1 1 64686564 67880900 −0.6106 −0.0017 1.9999 −0.0023 2 0WCM163_Z7_1 1 67885713 114646337 0.3348 1.0028 2.029 1.9788 2 2WCM163_Z7_1 1 114680276 116675831 −0.5851 0.026 NA NA NA NA WCM163_Z7_11 116916851 120611489 0.3059 0.9726 2.0771 1.8476 2 2 WCM163_Z7_1 1120611968 249212557 0.8618 1.5489 3.9322 1.9196 4 2 WCM163_Z7_1 10225980 135440080 −0.0721 0.5754 1.9963 0.9839 2 1 WCM163_Z7_1 11 193106134856534 −0.0869 0.5597 1.9516 0.9963 2 1 WCM163_Z7_1 12 14867412879241 −0.5995 0.0104 2.0237 −0.0093 2 0 WCM163_Z7_1 12 1293987233592436 −1.4442 −0.9371 1.0402 0.0044 1 0 WCM163_Z7_1 12 34175539133810735 −0.6064 0.0029 1.014 0.99 1 1 WCM163_Z7_1 13 19600515 222755410.2854 0.9512 NA NA NA NA WCM163_Z7_1 13 23238161 24334681 −0.59440.0159 2.0542 −0.0321 2 0 WCM163_Z7_1 13 24380087 32841457 0.2931 0.95932.0093 1.8793 2 2 WCM163_Z7_1 13 32849042 48919320 −0.5891 0.0216 2.01140.0188 2 0 WCM163_Z7_1 13 48947628 49865887 −3.4303 −3.9035 NA NA NA NAWCM163_Z7_1 13 49885021 70681598 −0.5821 0.0292 2.0315 0.0094 2 0WCM163_Z7_1 13 72014800 115089411 −0.0633 0.5847 2.0043 0.9951 2 1WCM163_Z7_1 14 19377719 71576774 −0.0784 0.5687 1.9667 0.9996 2 1WCM163_Z7_1 14 72040288 107283184 0.3162 0.9834 1.9936 1.9606 2 2WCM163_Z7_1 15 20169912 59523960 −0.0685 0.5792 2 0.9881 2 1 WCM163_Z7_115 59528860 102506276 −0.6131 −0.0045 1.0142 0.9795 1 1 WCM163_Z7_1 1666966 71319801 −0.0827 0.5642 1.9795 0.9776 2 1 WCM163_Z7_1 16 7139274190162182 −1.4646 −0.9609 1.0286 −0.0011 1 0 WCM163_Z7_1 17 1315957478703 −0.0759 0.5714 1.9846 0.9873 2 1 WCM163_Z7_1 17 7479880 7977032−0.7388 −0.1417 1.8343 −0.0214 2 0 WCM163_Z7_1 17 7978932 810835260.3122 0.9793 1.9818 1.9612 2 2 WCM163_Z7_1 18 49039 32864519 0.30180.9684 1.9811 1.9321 2 2 WCM163_Z7_1 18 32864994 78005210 −0.0741 0.57332.0297 0.9462 2 1 WCM163_Z7_1 19 281499 24310731 0.3097 0.9766 1.98421.9514 2 2 WCM163_Z7_1 19 29567134 53995279 −0.6375 −0.031 1.9592−0.0017 2 0 WCM163_Z7_1 19 54072640 59083968 0.2712 0.9364 1.9257 1.90172 2 WCM163_Z7_1 2 41614 95537463 0.3203 0.9877 2.9662 0.9998 3 1WCM163_Z7_1 2 95537770 127839416 −0.5952 0.015 1.0335 0.9874 1 1WCM163_Z7_1 2 127944890 128284004 −1.4578 −0.953 NA NA NA NA WCM163_Z7_12 128284225 216986843 −0.6124 −0.0037 1.0169 0.9779 1 1 WCM163_Z7_1 2216990755 220505600 −0.0958 0.5503 1.9809 0.9478 2 1 WCM163_Z7_1 2220506380 242946616 −0.6091 −1.00E−04 1.0173 0.9826 1 1 WCM163_Z7_1 2068351 62904890 0.3046 0.9713 1.9709 1.9504 2 2 WCM163_Z7_1 21 982622539818748 0.2806 0.9463 1.951 1.9027 2 2 WCM163_Z7_1 21 39947601 42866383−0.6125 −0.0038 2.0036 −0.0089 2 0 WCM163_Z7_1 21 42870049 480842140.297 0.9633 1.9742 1.9253 2 2 WCM163_Z7_1 22 17063440 50893487 −0.609 01.0794 0.9207 1 1 WCM163_Z7_1 22 50893569 51215115 −0.0999 0.5459 1.85751.0624 2 1 WCM163_Z7_1 3 239377 46063329 −0.066 0.5819 1.9608 1.0327 2 1WCM163_Z7_1 3 46244879 52730331 −0.5985 0.0114 2.013 0.0028 2 0WCM163_Z7_1 3 52730673 71247064 −0.0357 0.6138 2.0333 1.0273 2 1WCM163_Z7_1 3 71247462 75478292 −0.5856 0.0254 NA NA NA NA WCM163_Z7_1 375832483 197894720 −0.0784 0.5687 1.9652 1.0012 2 1 WCM163_Z7_1 4 5932749063842 −0.0703 0.5773 1.9815 1.0025 2 1 WCM163_Z7_1 4 5270980398480213 −0.5934 0.017 2.0315 −0.0078 2 0 WCM163_Z7_1 4 98633927100470508 0.2958 0.9621 NA NA NA NA WCM163_Z7_1 4 100472128 110880530−0.6432 −0.0372 1.9989 −0.0498 2 0 WCM163_Z7_1 4 110882078 184633769−0.073 0.5744 1.9682 1.01 2 1 WCM163_Z7_1 4 184827965 186337006 0.55871.2357 4.687 0.0229 5 0 WCM163_Z7_1 4 186339611 187348117 −0.4995 0.11872.1845 −0.0131 2 0 WCM163_Z7_1 4 187455127 190396320 −0.6291 −0.0218 NANA NA NA WCM163_Z7_1 5 140532 9630067 0.3068 0.9736 2.015 1.9125 2 2WCM163_Z7_1 5 10227673 11903945 −0.6293 −0.0221 NA NA NA NA WCM163_Z7_15 13692218 50129872 0.2997 0.9662 1.9536 1.9536 2 2 WCM163_Z7_1 550130675 148639132 −0.6038 0.0057 1.9967 0.0112 2 0 WCM163_Z7_1 5148679086 180687808 0.3126 0.9796 1.972 1.972 2 2 WCM163_Z7_1 6 20361910415173 −0.1098 0.5354 1.9026 0.9961 2 1 WCM163_Z7_1 6 1041968031503233 0.2873 0.9532 1.9584 1.9139 2 2 WCM163_Z7_1 6 31540784 75977432−0.0754 0.5719 1.9931 0.9798 2 1 WCM163_Z7_1 6 75994283 76332511 −1.4163−0.9045 NA NA NA NA WCM163_Z7_1 6 76333621 170893415 −0.0767 0.57051.9834 0.9867 2 1 WCM163_Z7_1 7 193254 72400606 −0.0776 0.5696 1.96641.0018 2 1 WCM163_Z7_1 7 72409165 131060212 0.3162 0.9834 2.004 1.9503 22 WCM163_Z7_1 7 131071891 144096925 −0.0881 0.5584 1.9639 0.9814 2 1WCM163_Z7_1 7 144097354 158937013 0.3074 0.9743 1.9954 1.9339 2 2WCM163_Z7_1 8 190907 62626884 −0.0854 0.5613 1.9647 0.9865 2 1WCM163_Z7_1 8 63161664 146279480 0.3115 0.9785 1.989 1.952 2 2WCM163_Z7_1 9 116846 131493649 0.3095 0.9764 1.9819 1.9531 2 2WCM163_Z7_1 9 131495750 132816234 −0.0901 0.5563 1.9751 0.9659 2 1WCM163_Z7_1 9 132837968 141111414 0.3364 1.0045 2.0272 1.9854 2 2WCM163_Z7_1 X 2707716 154509348 0.2148 0.8774 NA NA NA NA WCM164 1 14930249213967 −0.033 −0.1813 0.8819 0.8819 1 1 WCM164 10 226100 1354390190.0077 0.3635 1.2866 1.2866 1 1 WCM164 11 193096 134605959 −0.011 0.13621.099 1.099 1 1 WCM164 12 148414 133810703 −0.0165 0.0629 1.0445 1.04451 1 WCM164 13 19041992 115089411 −0.1247 −6.8365 0.0088 0.0088 0 0WCM164 14 19110263 107283270 −0.0591 −0.6714 0.6279 0.6279 1 1 WCM164 1520083896 102506237 −0.0226 −0.0225 0.9845 0.9845 1 1 WCM164 16 6693090168646 −0.0362 −0.2338 0.8504 0.8504 1 1 WCM164 17 131595 81187875−0.0633 −0.7671 0.5876 0.5876 1 1 WCM164 18 47610 78005197 −0.082−1.2916 0.4085 0.4085 0 0 WCM164 19 105050 844077 0.1202 1.3041 3.63511.3034 4 1 WCM164 19 846272 19166817 −0.0842 −1.3657 0.388 0.388 0 0WCM164 19 19168336 59093425 0.0653 0.9115 1.881 1.881 2 2 WCM164 2 41602243037022 −0.0453 −0.3932 0.7614 0.7614 1 1 WCM164 20 68406 629345720.0126 0.4183 1.3363 1.3363 1 1 WCM164 21 9590368 48084204 −0.0375−0.2555 0.8377 0.8377 1 1 WCM164 22 16159079 51219129 −0.027 −0.08820.9407 0.9407 1 1 WCM164 3 239524 197896705 −0.0347 −0.2093 0.86490.8649 1 1 WCM164 4 53428 190878479 −0.019 0.0284 1.0199 1.0199 1 1WCM164 5 90696 180687776 −0.0325 −0.1744 0.8861 0.8861 1 1 WCM164 6203374 26368360 −0.0682 −0.8888 0.5401 0.5401 1 1 WCM164 6 2637063486195006 0.0355 0.6512 1.5705 1.5705 2 2 WCM164 6 86195167 170892848−0.1243 −6.3259 0.0125 0.0125 0 0 WCM164 7 193253 158937046 0.03770.6723 1.5936 1.5936 2 2 WCM164 8 163506 42231674 −0.0862 −1.4404 0.36850.3685 0 0 WCM164 8 42231845 144657760 0.2013 1.7569 3.3797 3.3797 3 3WCM164 8 144658262 146279547 0.0333 0.6301 2.2152 0.8801 2 1 WCM164 9116774 141107495 −0.0298 −0.1314 0.913 0.913 1 1 WCM164 X 2700110154509348 −0.0465 −0.4148 NA NA NA NA WCM164_X1_1 1 69635 2408142−0.1825 0.6373 1.9209 1.19 2 1 WCM164_X1_1 1 2410049 20680456 −0.8557−0.731 1.1041 0.1009 1 0 WCM164_X1_1 1 20680600 249212402 −0.1868 0.63022.014 1.0815 2 1 WCM164_X1_1 10 255939 84745256 0.2678 1.3171 2.9282.0551 3 2 WCM164_X1_1 10 85901270 88446833 −0.1692 0.6591 2.8068 0.35153 0 WCM164_X1_1 10 88451790 90354519 0.1921 1.2098 2.6079 2.0182 3 2WCM164_X1_1 10 90356656 101124261 0.4675 1.5897 3.8318 2.1878 4 2WCM164_X1_1 10 101124720 101515420 0.3837 1.477 NA NA NA NA WCM164_X1_110 101542607 103384550 −0.4903 0.0901 1.9934 0.1354 2 0 WCM164_X1_1 10103427711 121612629 0.4507 1.5673 3.7919 2.1352 4 2 WCM164_X1_1 10121616863 121663703 0.1085 1.0884 NA NA NA NA WCM164_X1_1 10 121668592124214448 −0.5586 −0.0455 1.9692 −0.0313 2 0 WCM164_X1_1 10 124214532135440086 0.0514 1.0037 2.0232 1.9871 2 2 WCM164_X1_1 11 193152 178682450.0382 0.9838 2.21 1.7454 2 2 WCM164_X1_1 11 17940305 18436773 −0.51860.0348 1.9192 0.1296 2 0 WCM164_X1_1 11 18456308 134856536 0.0321 0.97471.9771 1.9533 2 2 WCM164_X1_1 12 148644 26383903 0.2891 1.3468 2.90852.1786 3 2 WCM164_X1_1 12 26405818 133780851 0.0607 1.0177 2.0519 1.99752 2 WCM164_X1_1 12 133781072 133810703 0.1941 1.2127 NA NA NA NAWCM164_X1_1 13 19600515 115089411 −0.4838 0.1026 2.1126 0.0348 2 0WCM164_X1_1 14 19377692 20470519 −0.1082 0.7573 2.2123 1.1684 2 1WCM164_X1_1 14 20470737 63749879 −0.1589 0.6758 2.0157 1.1793 2 1WCM164_X1_1 14 63757641 65569057 −0.4822 0.1058 2.1473 0.0048 2 0WCM164_X1_1 14 65734340 71444717 0.0645 1.0233 2.1054 1.9598 2 2WCM164_X1_1 14 71445100 73538368 −0.5329 0.0063 NA NA NA NA WCM164_X1_114 73543046 107283203 0.0808 1.0476 2.0917 2.0426 2 2 WCM164_X1_1 1520170150 41772425 −0.1607 0.6729 2.0301 1.1584 2 1 WCM164_X1_1 1541772812 43699658 −0.8487 −0.7123 1.0661 0.1546 1 0 WCM164_X1_1 1543700203 102506273 −0.1869 0.6301 1.9502 1.1451 2 1 WCM164_X1_1 16 6760472170625 0.0725 1.0352 2.0677 2.0311 2 2 WCM164_X1_1 16 7217327974334954 −0.7697 −0.5125 NA NA NA NA WCM164_X1_1 16 74335498 755641500.0994 1.0751 2.2188 1.9951 2 2 WCM164_X1_1 16 75565504 83983920 −0.49640.0782 2.0198 0.0916 2 0 WCM164_X1_1 16 83984894 84651466 0.0922 1.06452.1996 1.9832 2 2 WCM164_X1_1 16 84684517 85138998 −0.4833 0.1037 2.10970.0393 2 0 WCM164_X1_1 16 85141491 88933013 0.1411 1.1362 2.2652 2.13092 2 WCM164_X1_1 16 88943648 90233622 0.4383 1.5507 3.7548 2.1044 4 2WCM164_X1_1 17 131595 21191309 −0.4944 0.0822 2.0344 0.0828 2 0WCM164_X1_1 17 21194843 27067924 0.1691 1.1767 2.9258 1.5955 3 2WCM164_X1_1 17 27068131 74527752 −0.1808 0.64 2.0701 1.0467 2 1WCM164_X1_1 17 74533540 81083455 0.2775 1.3306 2.9439 2.0863 3 2WCM164_X1_1 18 48238 78005197 −0.4816 0.107 2.0947 0.0593 2 0WCM164_X1_1 19 281498 2015331 0.1007 1.0771 2.3368 1.8827 2 2WCM164_X1_1 19 2039707 14591479 −0.5021 0.0671 2.0017 0.0934 2 0WCM164_X1_1 19 14593667 16686944 0.4727 1.5966 4.0746 1.9739 4 2WCM164_X1_1 19 16687339 17327069 0.0751 1.0391 NA NA NA NA WCM164_X1_119 17328276 18562382 −0.5189 0.0342 1.9469 0.101 2 0 WCM164_X1_1 1918569116 34934811 0.0645 1.0233 2.1023 1.9628 2 2 WCM164_X1_1 1934935949 35614212 −0.4385 0.1889 2.1627 0.117 2 0 WCM164_X1_1 1935616191 42497555 0.0588 1.0148 2.2592 1.782 2 2 WCM164_X1_1 19 4252546142799297 −0.4973 0.0764 NA NA NA NA WCM164_X1_1 19 42801345 590839530.4384 1.5508 3.8455 2.0142 4 2 WCM164_X1_1 2 41615 242946597 −0.18610.6314 2.0232 1.075 2 1 WCM164_X1_1 20 68396 62904847 −0.151 0.68871.9357 1.2879 2 1 WCM164_X1_1 21 9826203 10910347 −0.5671 −0.0629 NA NANA NA WCM164_X1_1 21 10914363 17566741 −0.4362 0.1933 NA NA NA NAWCM164_X1_1 21 17763960 39817521 0.0757 1.0401 2.1144 1.9982 2 2WCM164_X1_1 21 39818748 42817383 −0.503 0.0653 1.9815 0.1111 2 0WCM164_X1_1 21 42817930 48084277 0.1161 1.0996 2.2309 2.0549 2 2WCM164_X1_1 22 16287446 39267732 0.2807 1.335 3.0266 2.019 3 2WCM164_X1_1 22 39353703 51215120 −0.1875 0.6291 2.0508 1.0423 2 1WCM164_X1_1 3 239350 4759080 0.0494 1.0008 2.2081 1.794 2 2 WCM164_X1_13 4767244 4942294 −1.2976 −2.4761 NA NA NA NA WCM164_X1_1 3 50214039857817 −0.5046 0.0622 2.0558 0.0322 2 0 WCM164_X1_1 3 9859380 465097450.0625 1.0203 2.0284 2.0284 2 2 WCM164_X1_1 3 46539556 65607679 0.28351.339 2.6603 2.3991 3 2 WCM164_X1_1 3 66023739 73114621 −0.4847 0.10092.0734 0.0714 2 0 WCM164_X1_1 3 73432623 123550262 0.2828 1.3379 2.84542.2104 3 2 WCM164_X1_1 3 123616407 124998008 −0.2022 0.6048 2.9475 0.0943 0 WCM164_X1_1 3 125006994 175181248 0.2747 1.3267 2.803 2.2136 3 2WCM164_X1_1 3 175184925 176768376 0.2039 1.2267 NA NA NA NA WCM164_X1_13 176769343 197894712 −0.1895 0.6258 2.9926 0.0935 3 0 WCM164_X1_1 459334 190426502 0.0641 1.0227 2.056 2.0075 2 2 WCM164_X1_1 5 14053288100493 0.0184 0.954 1.9549 1.9197 2 2 WCM164_X1_1 5 89689917 108523200−0.5568 −0.0419 1.9255 0.0172 2 0 WCM164_X1_1 5 108673043 1327633510.0083 0.9386 1.9896 1.8438 2 2 WCM164_X1_1 5 132918994 134130562 −0.575−0.0789 NA NA NA NA WCM164_X1_1 5 134131770 180687766 0.0153 0.94931.9514 1.9104 2 2 WCM164_X1_1 6 203479 25520513 −0.5032 0.0649 2.03220.0598 2 0 WCM164_X1_1 6 25529050 33556747 0.069 1.03 2.0755 2.0086 2 2WCM164_X1_1 6 33560992 38950227 0.7641 1.9727 5.7719 2.0781 6 2WCM164_X1_1 6 38951998 47277181 1.0476 2.3203 7.9738 2.0152 8 2WCM164_X1_1 6 47471020 57372307 −0.178 0.6446 2.0298 1.0968 2 1WCM164_X1_1 6 57398163 74537868 0.2213 1.2514 3.0737 1.6876 3 2WCM164_X1_1 6 75794916 76564953 0.7477 1.9521 NA NA NA NA WCM164_X1_1 676570740 107956440 0.2741 1.3258 2.9485 2.0648 3 2 WCM164_X1_1 6107956582 170892708 −0.4815 0.1072 2.1365 0.0178 2 0 WCM164_X1_1 7193254 71275347 −0.1855 0.6323 2.0549 1.0451 2 1 WCM164_X1_1 7 71488741123672171 0.247 1.2878 3.801 1.0822 4 1 WCM164_X1_1 7 123672860131071908 0.0582 1.0139 3.9729 0.0658 4 0 WCM164_X1_1 7 131073716151855968 0.2673 1.3163 3.8933 1.0872 4 1 WCM164_X1_1 7 151859240152345741 −0.7929 −0.5695 NA NA NA NA WCM164_X1_1 7 152346092 1589370220.0837 1.0519 3.0536 1.0929 3 1 WCM164_X1_1 8 190907 28420424 −0.48270.1048 2.0196 0.1311 2 0 WCM164_X1_1 8 28573618 67417505 0.4749 1.59964.0584 2.0028 4 2 WCM164_X1_1 8 67422365 143746111 0.772 1.9827 5.90352.0011 6 2 WCM164_X1_1 8 143781858 146279441 0.4641 1.5852 5.9009 0.10016 0 WCM164_X1_1 9 17085 43884984 −0.4779 0.1141 2.0464 0.1182 2 0WCM164_X1_1 9 44870008 77112899 0.0453 0.9946 NA NA NA NA WCM164_X1_1 977230548 84208159 −0.4969 0.0772 1.99 0.12 2 0 WCM164_X1_1 9 84215027128725347 0.0785 1.0441 2.0621 2.0621 2 2 WCM164_X1_1 9 128728183141111414 −0.184 0.6349 2.0532 1.0525 2 1 WCM164_X1_1 X 2707687154509348 0.044 0.9926 NA NA NA NA WCM169 1 14930 249213973 0.02180.3259 1.2535 1.2535 1 1 WCM169 10 226091 135438982 0.0084 0.1339 1.09731.0973 1 1 WCM169 11 193096 62327934 0.0387 0.539 1.453 1.453 1 1 WCM16911 62334423 71150131 −0.0842 −4.1943 0.0546 0.0546 0 0 WCM169 1171152328 134605916 0.0178 0.271 1.2067 1.2067 1 1 WCM169 12 148637133810883 −0.0085 −0.1484 0.9022 0.9022 1 1 WCM169 13 19041937 115089411−0.0228 −0.4372 0.7386 0.7386 1 1 WCM169 14 19110239 107283270 −0.0093−0.1637 0.8927 0.8927 1 1 WCM169 15 20083896 102506238 0.0226 0.33661.2628 1.2628 1 1 WCM169 16 64401 90168646 −0.0015 −0.0257 0.9823 0.98231 1 WCM169 17 131595 81187934 −8.00E−04 −0.0137 0.9906 0.9906 1 1 WCM16918 47711 78005203 −0.0159 −0.2906 0.8176 0.8176 1 1 WCM169 19 10506959093645 −0.0155 −0.2837 0.8215 0.8215 1 1 WCM169 2 41585 243037039−0.0035 −0.0595 0.9596 0.9596 1 1 WCM169 20 68427 62934623 0.0229 0.34041.2661 1.2661 1 1 WCM169 21 9590334 48084177 −0.0077 −0.1339 0.91140.9114 1 1 WCM169 22 16159060 51215157 0.0184 0.279 1.2134 1.2134 1 1WCM169 3 239451 197896711 −0.0048 −0.0824 0.9445 0.9445 1 1 WCM169 453359 190903980 −0.0067 −0.1165 0.9224 0.9224 1 1 WCM169 5 90680180687808 −0.0107 −0.1896 0.8769 0.8769 1 1 WCM169 6 203561 170892869−0.0082 −0.1438 0.9051 0.9051 1 1 WCM169 7 193253 158937022  2.00E−040.004 1.0028 1.0028 1 1 WCM169 8 163438 146279483 −0.0099 −0.1751 0.88570.8857 1 1 WCM169 9 14886 141071710 0.0173 0.2641 1.2009 1.2009 1 1WCM169 X 2700151 154493590 0.0333 0.4745 NA NA NA NA WCM169_X1_1 1 69603249212164 −0.0365 0.064 1.2262 0.8645 1 1 WCM169_X1_1 10 225979135440080 −0.0983 −0.68 0.7012 0.5472 1 1 WCM169_X1_1 11 193154134856604 −0.0621 −0.2033 1.0659 0.6712 1 1 WCM169_X1_1 12 148811133810842 −0.0677 −0.269 1.0265 0.6333 1 1 WCM169_X1_1 13 19600515115089411 −0.091 −0.5721 0.721 0.6243 1 1 WCM169_X1_1 14 19377711107283034 −0.0303 0.1219 1.1992 0.9772 1 1 WCM169_X1_1 15 20170156102506273 −0.0327 0.0997 1.3032 0.8399 1 1 WCM169_X1_1 16 66930 901615800.0052 0.4219 1.4328 1.2467 1 1 WCM169_X1_1 17 131595 81083455 0.02520.5698 1.5578 1.411 2 1 WCM169_X1_1 18 48201 78005164 −0.0492 −0.06351.0366 0.8773 1 1 WCM169_X1_1 19 281404 59083985 0.0118 0.4722 1.56381.2107 2 1 WCM169_X1_1 2 41614 242946597 −0.0485 −0.0563 1.0315 0.892 11 WCM169_X1_1 20 68397 62904925 0.0157 0.5011 1.5195 1.3112 2 1WCM169_X1_1 21 9826225 48084214 −0.034 0.0876 1.133 0.9921 1 1WCM169_X1_1 22 17063476 51215123 0.0201 0.5334 1.5518 1.3428 2 1WCM169_X1_1 3 239405 197896714 −0.0132 0.2731 1.2798 1.1369 1 1WCM169_X1_1 4 59345 190426502 −0.1152 −0.966 0.607 0.4168 1 0WCM169_X1_1 5 140538 180687776 −0.0911 −0.5729 0.74 0.6046 1 1WCM169_X1_1 6 203699 170893450 −0.0609 −0.1896 1.0744 0.6793 1 1WCM169_X1_1 7 193253 158937135 −0.0942 −0.6183 1.2884 0.0144 1 0WCM169_X1_1 8 190907 146279434 −0.1115 −0.8992 0.6316 0.4408 1 0WCM169_X1_1 9 17084 141111414 −0.087 −0.515 0.7677 0.6319 1 1WCM169_X1_1 X 2707716 154509348 −0.0992 −0.6945 NA NA NA NA WCM170 117465 249214018 −0.0186 0.1415 1.103 1.103 1 1 WCM170 10 225982135439032 −0.0374 −0.1253 0.9168 0.9168 1 1 WCM170 11 193096 134320514−0.0018 0.3467 1.2716 1.2716 1 1 WCM170 12 148444 133810832 0.0256 0.6331.5508 1.5508 2 2 WCM170 13 19042005 115089411 −0.0793 −0.9703 0.51040.5104 1 1 WCM170 14 19110239 107283156 −0.0481 −0.3008 0.8118 0.8118 11 WCM170 15 20083896 102506273 −0.0287 0.0044 1.0031 1.0031 1 1 WCM17016 67688 90260461 −0.0503 −0.3398 0.7902 0.7902 1 1 WCM170 17 13159581052563 −0.0641 −0.6074 0.6564 0.6564 1 1 WCM170 18 47682 78005201−0.0881 −1.2295 0.4265 0.4265 0 0 WCM170 19 105069 59093696 −0.0427−0.2089 0.8652 0.8652 1 1 WCM170 2 41474 243037103 −0.0232 0.0808 1.05761.0576 1 1 WCM170 20 68319 62934623 0.0091 0.4676 1.3828 1.3828 1 1WCM170 21 9590370 48084189 −0.0405 −0.1742 0.8862 0.8862 1 1 WCM170 2216159014 51219090 −0.0296 −0.0084 0.9942 0.9942 1 1 WCM170 3 239436197896656 −0.0245 0.0634 1.0449 1.0449 1 1 WCM170 4 53360 190878508−0.0965 −1.5264 0.3471 0.3471 0 0 WCM170 5 90680 45261219 0.0542 0.88571.8476 1.8476 2 2 WCM170 5 45261346 140957127 −0.1334 −8.5453 0.00270.0027 0 0 WCM170 5 140957746 180687821 −0.0151 0.1864 1.1379 1.1379 1 1WCM170 6 203545 170892848 −0.0581 −0.4847 0.7146 0.7146 1 1 WCM170 7193222 158937011 0.0277 0.6532 1.5727 1.5727 2 2 WCM170 8 163527146279544 0.0295 0.6701 1.5912 1.5912 2 2 WCM170 9 116855 1411075320.0229 0.6069 1.523 1.523 2 2 WCM170 X 2700125 154493609 −0.0128 0.2152NA NA NA NA WCM170_Z1_1 1 69603 249212557 −0.0642 −0.0388 0.9869 0.96011 1 WCM170_Z1_1 10 225980 135440068 −0.0831 −0.0914 0.9518 0.9254 1 1WCM170_Z1_1 11 193113 77409733 −0.0397 0.0277 1.199 0.8397 1 1WCM170_Z1_1 11 77412026 134856542 0.1901 0.5748 1.997 0.9819 2 1WCM170_Z1_1 12 148644 38714925 −0.0156 0.0912 1.1261 1.0043 1 1WCM170_Z1_1 12 39047837 73015527 0.2944 0.7897 2.4596 0.9978 2 1WCM170_Z1_1 12 73046114 117365827 0.4683 1.1165 3.3875 0.9488 3 1WCM170_Z1_1 12 117383210 133810703 0.3011 0.803 2.4756 1.0139 2 1WCM170_Z1_1 13 19600365 115089411 −0.1036 −0.1496 0.9249 0.878 1 1WCM170_Z1_1 14 19377692 107283027 −0.0787 −0.0788 0.976 0.9177 1 1WCM170_Z1_1 15 20170150 57839587 −0.0406 0.0252 1.1944 0.8408 1 1WCM170_Z1_1 15 57891898 63009804 −0.244 −0.5996 1.0852 0.2347 1 0WCM170_Z1_1 15 63012010 77908028 −0.0478 0.0058 1.042 0.9662 1 1WCM170_Z1_1 15 77926631 78894604 −0.2811 −0.7372 1.1571 0.0427 1 0WCM170_Z1_1 15 78909398 84287031 −0.0403 0.026 1.1243 0.9121 1 1WCM170_Z1_1 15 84324566 89074314 −0.3875 −1.1966 1.078 −0.2054 1 0WCM170_Z1_1 15 89074587 102506273 −0.0407 0.025 1.0556 0.9794 1 1WCM170_Z1_1 16 67604 90233599 −0.0471 0.0079 1.0271 0.9838 1 1WCM170_Z1_1 17 131595 7214789 −0.0783 −0.0778 0.982 0.913 1 1WCM170_Z1_1 17 7214960 19705108 −0.3654 −1.0917 1.06 −0.1216 1 0WCM170_Z1_1 17 19708017 54872439 −0.0812 −0.0859 0.966 0.9184 1 1WCM170_Z1_1 17 54892235 56811549 −0.3402 −0.9784 0.8634 0.1517 1 0WCM170_Z1_1 17 56833502 81083455 −0.0597 −0.0264 0.9926 0.9711 1 1WCM170_Z1_1 18 48266 78005164 −0.331 −0.9386 1.1135 −0.07 1 0WCM170_Z1_1 19 281424 3767338 −0.3088 −0.8465 1.044 0.0682 1 0WCM170_Z1_1 19 3770696 42728723 −0.0507 −0.0018 1.0231 0.9744 1 1WCM170_Z1_1 19 42728836 46997897 −0.3518 −1.0297 1.0379 −0.0583 1 0WCM170_Z1_1 19 46998236 59083923 −0.0641 −0.0384 1.0085 0.9389 1 1WCM170_Z1_1 2 41614 103149100 −0.0571 −0.0194 1.0082 0.9651 1 1WCM170_Z1_1 2 103236360 112917368 0.2656 0.7319 1.8525 1.4691 2 1WCM170_Z1_1 2 112922704 234959741 −0.0697 −0.0539 0.99 0.9367 1 1WCM170_Z1_1 2 234967560 242946604 −0.3549 −1.0435 1.0321 −0.0618 1 0WCM170_Z1_1 20 68373 33122595 −0.0273 0.0605 1.084 1.0016 1 1WCM170_Z1_1 20 33122709 62904863 0.2571 0.7147 2.1227 1.1597 2 1WCM170_Z1_1 21 9826225 48084282 −0.0692 −0.0525 1.0283 0.9003 1 1WCM170_Z1_1 22 16287461 51215142 −0.063 −0.0355 1.0078 0.9435 1 1WCM170_Z1_1 3 239405 70014274 −0.0426 0.02 1.0303 0.9977 1 1 WCM170_Z1_13 71007463 88199313 −0.3566 −1.051 NA NA NA NA WCM170_Z1_1 3 88202415172353810 −0.0378 0.0328 1.0448 1.0012 1 1 WCM170_Z1_1 3 172363447197894726 0.1801 0.5533 1.9271 1.0078 2 1 WCM170_Z1_1 4 59391 66217296−0.0829 −0.0907 0.9813 0.8968 1 1 WCM170_Z1_1 4 66218767 190426471−0.3788 −1.1544 0.9571 −0.0586 1 0 WCM170_Z1_1 5 140538 45695959 0.2390.6775 2.2499 0.9488 2 1 WCM170_Z1_1 5 49698142 133537659 −0.2795 −0.7310.9759 0.229 1 0 WCM170_Z1_1 5 133541598 180687812 0.1058 0.3876 2.30180.3146 2 0 WCM170_Z1_1 6 203577 165895824 −0.0586 −0.0234 1.0108 0.95711 1 WCM170_Z1_1 6 165956988 168695345 −0.338 −0.9687 0.8519 0.1701 1 0WCM170_Z1_1 6 168708354 170893406 −0.0861 −0.0998 1.0702 0.7961 1 1WCM170_Z1_1 7 193254 14026288 0.1243 0.4299 1.4356 1.2587 1 1WCM170_Z1_1 7 14027756 66774614 0.3354 0.87 1.8806 1.7747 2 2WCM170_Z1_1 7 69064936 158937416 0.0677 0.2983 1.9921 0.4673 2 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NA NANA NA WCM170_Z16_1 10 91486160 135440108 −0.1102 −0.0601 0.9592 0.9592 11 WCM170_Z16_1 11 193100 3661375 −0.0557 0.01 1.1874 0.8265 1 1WCM170_Z16_1 11 3661536 4929430 0.5129 0.7046 2.1057 1.1537 2 1WCM170_Z16_1 11 4936253 6292743 −0.0306 0.042 1.0296 1.0296 1 1WCM170_Z16_1 11 6340480 7111436 0.6767 0.8949 2.7204 0.9986 3 1WCM170_Z16_1 11 7256057 134856603 −0.0555 0.0102 1.0174 0.9968 1 1WCM170_Z16_1 12 148811 17142456 −0.0481 0.0197 1.0384 0.9891 1 1WCM170_Z16_1 12 17826313 33031940 0.5411 0.7376 2.3069 1.028 2 1WCM170_Z16_1 12 33049563 55969088 −0.0478 0.0201 1.9887 0.0394 2 0WCM170_Z16_1 12 56030806 72863602 0.3805 0.548 1.9068 1.0173 2 1WCM170_Z16_1 12 72866880 78598891 1.0827 1.3536 NA NA NA NA WCM170_Z16_112 78604205 89916595 0.6458 0.8593 3.6042 0.024 4 0 WCM170_Z16_1 1289917037 117476976 0.9835 1.243 3.7973 0.9365 4 1 WCM170_Z16_1 12117479762 130185206 0.7331 0.9596 2.8601 1.0296 3 1 WCM170_Z16_1 12130387852 133810703 0.371 0.5366 1.8456 1.0555 2 1 WCM170_Z16_1 1319600365 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1.07251.0457 1 1 WCM170_Z16_1 17 49357388 57043188 −0.5982 −0.7299 1.16760.0383 1 0 WCM170_Z16_1 17 57043561 81083455 0.034 0.1239 1.0979 1.08141 1 WCM170_Z16_1 18 48221 78005197 −0.668 −0.8335 1.0696 0.0527 1 0WCM170_Z16_1 19 281404 3760211 −0.6293 −0.7758 1.1306 0.0375 1 0WCM170_Z16_1 19 3762752 42603950 0.0211 0.1076 1.0869 1.0679 1 1WCM170_Z16_1 19 42621155 47030244 −0.6611 −0.8232 1.0845 0.0458 1 0WCM170_Z16_1 19 47104178 59083985 0 0.081 1.0671 1.0484 1 1 WCM170_Z16_12 41615 103149100 −0.0242 0.0502 1.0512 1.0196 1 1 WCM170_Z16_1 2103236321 112834794 0.4101 0.5833 2.0198 0.9766 2 1 WCM170_Z16_1 2112838655 185803742 −0.0374 0.0333 1.0338 1.0129 1 1 WCM170_Z16_1 2186603429 190044287 −0.6636 −0.8269 1.0289 0.0986 1 0 WCM170_Z16_1 2190306233 234969119 −0.0359 0.0353 1.0352 1.0143 1 1 WCM170_Z16_1 2234975919 242946604 −0.6511 −0.8083 1.1358 0.0063 1 0 WCM170_Z16_1 2068351 36761253 0.0092 0.0926 1.0757 1.0568 1 1 WCM170_Z16_1 20 3676663362867958 0.4605 0.6429 2.0537 1.0693 2 1 WCM170_Z16_1 20 6286866562904881 0.4831 0.6695 NA NA NA NA WCM170_Z16_1 21 9826230 364211430.0313 0.1205 1.1254 1.0488 1 1 WCM170_Z16_1 21 36422352 48084226−0.6722 −0.8399 1.069 0.0484 1 0 WCM170_Z16_1 22 16287495 508324180.0147 0.0995 1.0809 1.0619 1 1 WCM170_Z16_1 22 50845151 51215123−0.6146 −0.754 1.1381 0.0478 1 0 WCM170_Z16_1 3 239405 42954777 −0.02230.0526 1.0477 1.0266 1 1 WCM170_Z16_1 3 42956036 44673989 −0.6719−0.8394 NA NA NA NA WCM170_Z16_1 3 44683581 45772862 −0.0122 0.06542.044 0.0487 2 0 WCM170_Z16_1 3 45773610 88205677 −0.6459 −0.8005 1.07670.0716 1 0 WCM170_Z16_1 3 89156905 113046535 −0.0804 −0.0218 1.02430.9457 1 1 WCM170_Z16_1 3 113049242 114099624 0.6202 0.8297 NA NA NA NAWCM170_Z16_1 3 114462303 149638994 −0.0124 0.0652 1.0595 1.033 1 1WCM170_Z16_1 3 149677875 151599328 −0.7169 −0.9077 0.9805 0.0856 1 0WCM170_Z16_1 3 151986434 172163223 −0.0657 −0.0028 1.0288 0.9673 1 1WCM170_Z16_1 3 172165378 197894726 0.4512 0.6319 1.9691 1.1302 2 1WCM170_Z16_1 4 59331 67142617 −0.0957 −0.0414 0.988 0.9554 1 1WCM170_Z16_1 4 68355735 190426502 −0.7517 −0.9612 1.0038 0.0235 1 0WCM170_Z16_1 5 140515 45695803 0.3513 0.5131 1.8886 0.9656 2 1WCM170_Z16_1 5 49698142 133702132 −0.7457 −0.952 0.9931 0.0407 1 0WCM170_Z16_1 5 133707316 180687814 −0.0555 0.0102 1.9972 0.017 2 0WCM170_Z16_1 6 203619 27215741 −0.7136 −0.9027 1.0218 0.048 1 0WCM170_Z16_1 6 27215807 45459757 −0.054 0.0122 1.9648 0.0522 2 0WCM170_Z16_1 6 45480011 170893454 −0.7342 −0.9341 0.9929 0.0538 1 0WCM170_Z16_1 7 193222 14653016 −0.067 −0.0045 1.0084 0.9854 1 1WCM170_Z16_1 7 14661103 103629735 0.3705 0.536 1.9227 0.9771 2 1WCM170_Z16_1 7 103767338 158937416 −0.0393 0.031 1.0374 1.0061 1 1WCM170_Z16_1 8 190908 40011239 −0.66 −0.8215 1.1136 0.0181 1 0WCM170_Z16_1 8 40011352 55534097 0.3598 0.5232 1.7225 1.1518 2 1WCM170_Z16_1 8 55534806 64100165 −0.0586 0.0063 NA NA NA NA WCM170_Z16_18 65290081 134239876 0.4108 0.584 1.9354 1.0627 2 1 WCM170_Z16_1 8134239949 146279453 −0.0309 0.0417 1.0582 1.0005 1 1 WCM170_Z16_1 9116832 5361795 0.3325 0.4905 1.9651 0.8449 2 1 WCM170_Z16_1 9 54561647046864 −0.8022 −1.0402 NA NA NA NA WCM170_Z16_1 9 7049110 288889260.4154 0.5895 1.9031 1.1062 2 1 WCM170_Z16_1 9 32384732 141111414−0.0731 −0.0123 1.0017 0.9813 1 1 WCM170_Z16_1 X 2700125 65483487−0.0788 −0.0196 NA NA NA NA WCM170_Z16_1 X 65486383 66943533 3.01963.4036 NA NA NA NA WCM170_Z16_1 X 67268291 68840737 0.7674 0.9989 NA NANA NA WCM170_Z16_1 X 69176943 154509348 −0.1139 −0.0649 NA NA NA NAWCM172 1 17473 249214028 0.0197 NA NA NA NA NA WCM172 10 225936135477904 −0.0057 NA NA NA NA NA WCM172 11 193146 134605954 0.0198 NA NANA NA NA WCM172 12 148513 133810794 −0.0117 NA NA NA NA NA WCM172 1319041979 115089411 −0.0318 NA NA NA NA NA WCM172 14 19110401 1072831560.0095 NA NA NA NA NA WCM172 15 20083894 102515252 0.0082 NA NA NA NA NAWCM172 16 66870 90168646 −0.0022 NA NA NA NA NA WCM172 17 13159581187875 0.0172 NA NA NA NA NA WCM172 18 47716 78005205 0.0025 NA NA NANA NA WCM172 19 104963 59093696 −0.023 NA NA NA NA NA WCM172 2 41583243037103 −0.006 NA NA NA NA NA WCM172 20 68397 62934592 0.0349 NA NA NANA NA WCM172 21 9590301 48084214 0.0236 NA NA NA NA NA WCM172 2216159014 51219129 0.0424 NA NA NA NA NA WCM172 3 239436 197896705 0.0301NA NA NA NA NA WCM172 4 53446 190878508 0.0272 NA NA NA NA NA WCM172 590680 180687803 −0.0075 NA NA NA NA NA WCM172 6 203546 170892923 −0.0135NA NA NA NA NA WCM172 7 193253 158937158 0.0224 NA NA NA NA NA WCM172 8163461 43048915 −0.0455 NA NA NA NA NA WCM172 8 43052114 1459994470.1836 NA NA NA NA NA WCM172 8 145999815 146279514 0.059 NA NA NA NA NAWCM172 9 15903 141107533 0.0299 NA NA NA NA NA WCM172 X 2700174154507335 −0.082 NA NA NA NA NA WCM172_X1_1 1 721476 160971123 −0.14640.6446 2.045 1.0817 2 1 WCM172_X1_1 1 160990858 178820272 −0.3987 0.08632.1645 −0.0412 2 0 WCM172_X1_1 1 178821944 249212402 0.0584 1.02884.0409 0.0399 4 0 WCM172_X1_1 10 255883 135440090 −0.1567 0.624 1.99141.0909 2 1 WCM172_X1_1 11 193112 79133220 0.0604 1.0325 2.0744 2.0166 22 WCM172_X1_1 11 81601786 85340205 −0.4127 0.0514 NA NA NA NAWCM172_X1_1 11 85345210 134856603 0.0552 1.0231 2.0755 1.9892 2 2WCM172_X1_1 12 148639 49919969 −0.4084 0.0621 2.0246 0.0633 2 0WCM172_X1_1 12 49920011 97301389 0.0658 1.0419 2.0843 2.0335 2 2WCM172_X1_1 12 97303569 101017445 −0.3683 0.1604 NA NA NA NA WCM172_X1_112 101017811 121758244 0.0856 1.0767 2.1092 2.1092 2 2 WCM172_X1_1 12122064924 133810926 −0.3719 0.1515 2.1887 0.0328 2 0 WCM172_X1_1 1319600515 23914098 −0.1726 0.5917 2.1796 0.8345 2 1 WCM172_X1_1 1323914443 86370473 −0.4201 0.0327 2.0164 0.0295 2 0 WCM172_X1_1 1387045827 101944587 0.0796 1.0662 2.3828 1.8049 2 2 WCM172_X1_1 13101944688 115089411 −0.3735 0.1479 2.0992 0.1166 2 0 WCM172_X1_1 1419377711 105207214 0.0363 0.9896 2.0212 1.9502 2 2 WCM172_X1_1 14105207489 107283019 −0.3584 0.1841 2.1054 0.1667 2 0 WCM172_X1_1 1520170150 25326443 −0.2904 0.3407 1.94 0.5927 2 1 WCM172_X1_1 15 2532773964792505 −0.4126 0.0517 2.0611 0.0119 2 0 WCM172_X1_1 15 6491507567073865 −0.171 0.595 1.8763 1.1446 2 1 WCM172_X1_1 15 67212220 87097704−0.396 0.093 2.0373 0.0959 2 0 WCM172_X1_1 15 87099493 102517646 −0.13130.6747 2.0925 1.1001 2 1 WCM172_X1_1 16 66966 30456006 −0.0207 0.8862.0972 1.599 2 2 WCM172_X1_1 16 30456182 34578588 0.1732 1.2258 2.88921.7886 3 2 WCM172_X1_1 16 34649016 49823410 −0.0036 0.9174 NA NA NA NAWCM172_X1_1 16 49856589 90128851 −0.3898 0.1082 2.0765 0.0792 2 0WCM172_X1_1 16 90130117 90233299 0.2449 1.3436 NA NA NA NA WCM172_X1_117 131595 2268602 −0.4132 0.0502 2.1142 −0.0434 2 0 WCM172_X1_1 172270608 6558768 0.0307 0.9795 1.993 1.9506 2 2 WCM172_X1_1 17 65895427960958 −0.3996 0.084 1.9731 0.1468 2 0 WCM172_X1_1 17 7976251 810834190.0578 1.0278 2.0677 2.01 2 2 WCM172_X1_1 18 49030 78005215 −0.00490.9151 1.9133 1.8581 2 2 WCM172_X1_1 19 281467 18547530 −0.4116 0.0542.0479 0.0285 2 0 WCM172_X1_1 19 18547805 31767965 0.0656 1.0416 2.22161.8955 2 2 WCM172_X1_1 19 31768267 35504447 −0.4326  9.00E−04 1.92390.0773 2 0 WCM172_X1_1 19 35505284 37238741 0.1145 1.1265 2.3407 2.02592 2 WCM172_X1_1 19 37239013 50753870 −0.3945 0.0967 2.1385 2.00E−04 2 0WCM172_X1_1 19 50755952 59083970 −0.1608 0.6158 2.0619 1.0029 2 1WCM172_X1_1 2 41620 145255317 −0.1414 0.6547 2.0357 1.113 2 1WCM172_X1_1 2 145271267 152320118 −0.5328 −0.2714 NA NA NA NAWCM172_X1_1 2 152320365 172725301 −0.1744 0.5882 1.8684 1.1383 2 1WCM172_X1_1 2 172749765 175201998 −0.7383 −0.9688 NA NA NA NAWCM172_X1_1 2 175213425 234926011 −0.1418 0.6539 2.0471 1.0996 2 1WCM172_X1_1 2 234959482 240702118 −0.6623 −0.6824 1.2662 −0.0199 1 0WCM172_X1_1 2 240721541 242573252 −0.3606 0.1788 1.2074 1.0565 1 1WCM172_X1_1 2 242573369 242946607 −0.7398 −0.9749 NA NA NA NAWCM172_X1_1 20 68406 590525 −0.0363 0.8571 2.0308 1.592 2 2 WCM172_X1_120 590855 35695515 0.0828 1.0716 2.1018 2.1018 2 2 WCM172_X1_1 2035696443 62904925 −0.146 0.6456 2.1087 1.02 2 1 WCM172_X1_1 21 982623548084282 0.0562 1.025 2.0997 1.9701 2 2 WCM172_X1_1 22 16287461 503209410.051 1.0158 2.0614 1.9825 2 2 WCM172_X1_1 22 50354843 51219138 −0.4351−0.0054 1.941 0.0515 2 0 WCM172_X1_1 3 239588 93780303 0.2115 1.28922.488 2.3998 2 2 WCM172_X1_1 3 93781971 127806676 −0.2456 0.4388 2.70730.0037 3 0 WCM172_X1_1 3 127816309 168546914 0.1585 1.2012 2.3496 2.24912 2 WCM172_X1_1 3 168802763 195802175 0.566 1.832 5.1028 2.0179 5 2WCM172_X1_1 3 195803944 197894713 −0.4252 0.0197 1.8361 0.1914 2 0WCM172_X1_1 4 59394 344000 −0.0537 0.8245 NA NA NA NA WCM172_X1_1 4366483 57891653 0.0616 1.0346 2.0666 2.0305 2 2 WCM172_X1_1 4 57896500190426502 0.2048 1.2782 2.7047 2.1462 3 2 WCM172_X1_1 5 140636 54965423−0.1604 0.6165 2.0566 1.0097 2 1 WCM172_X1_1 5 54965688 115833060−0.4195 0.0341 2.0359 0.012 2 0 WCM172_X1_1 5 115838022 131728291 0.07231.0534 2.2355 1.9152 2 2 WCM172_X1_1 5 131729504 132902891 −0.39050.1064 NA NA NA NA WCM172_X1_1 5 132918987 140085278 −0.0241 0.87981.9661 1.7141 2 2 WCM172_X1_1 5 140166824 143200053 −0.3922 0.10232.0098 0.1371 2 0 WCM172_X1_1 5 143538043 169446096 0.0776 1.0626 2.14352.0339 2 2 WCM172_X1_1 5 169454923 174869239 −0.4176 0.0391 NA NA NA NAWCM172_X1_1 5 174869327 180687773 0.0828 1.0717 2.201 2.003 2 2WCM172_X1_1 6 203509 13807190 0.0101 0.9425 2.0299 1.8138 2 2WCM172_X1_1 6 13814338 22570064 −0.4076 0.0641 1.9066 0.1843 2 0WCM172_X1_1 6 22570479 80982916 0.0314 0.9808 2.009 1.9382 2 2WCM172_X1_1 6 81053489 153347598 −0.4138 0.0486 2.0164 0.0521 2 0WCM172_X1_1 6 153365130 170893411 −0.1335 0.6704 2.0775 1.1056 2 1WCM172_X1_1 7 193253 158937400 0.0487 1.0117 2.0522 1.9805 2 2WCM172_X1_1 8 190906 17539139 −0.4037 0.0738 2.0521 0.053 2 0WCM172_X1_1 8 17541999 30209791 −0.6722 −0.7173 1.0753 0.1412 1 0WCM172_X1_1 8 30210180 47752745 −0.4327  7.00E−04 2.0545 −0.0536 2 0WCM172_X1_1 8 47753945 146279424 1.1134 2.5668 9.9019 1.9483 10  2WCM172_X1_1 9 17086 5466769 −0.4063 0.0674 1.9202 0.1754 2 0 WCM172_X1_19 5467856 19328063 0.0566 1.0258 3.9837 0.0884 4 0 WCM172_X1_1 919332036 41954826 0.4354 1.6401 3.9968 2.2368 4 2 WCM172_X1_1 9 43624879103091424 0.0619 1.0351 2.0854 2.0131 2 2 WCM172_X1_1 9 103092362105765508 −0.4457 −0.033 NA NA NA NA WCM172_X1_1 9 105767036 1170643770.0337 0.9849 2.0855 1.8729 2 2 WCM172_X1_1 9 117066944 125143995−0.4244 0.0219 1.9129 0.1176 2 0 WCM172_X1_1 9 125145982 1264390140.0273 0.9735 1.9636 1.9636 2 2 WCM172_X1_1 9 126520068 130331147 −0.4320.0025 1.8305 0.173 2 0 WCM172_X1_1 9 130341207 141111414 0.0686 1.04682.095 2.037 2 2 WCM172_X1_1 X 2700141 37701149 −0.3679 0.1613 NA NA NANA WCM172_X1_1 X 37705579 65420492 0.056 1.0246 NA NA NA NA WCM172_X1_1X 65423237 154509348 0.3854 1.5643 NA NA NA NA WCM172_X2_1 1 721476979270 −0.1113 0.5712 NA NA NA NA WCM172_X2_1 1 979736 11007907 −0.06250.6281 1.9764 1.1146 2 1 WCM172_X2_1 1 11008238 43300805 −0.2373 0.4231.7511 0.9303 2 1 WCM172_X2_1 1 43304619 160971139 −0.1006 0.5838 1.94821.0493 2 1 WCM172_X2_1 1 160990852 178514702 −0.5577 0.034 1.978 0.06972 0 WCM172_X2_1 1 178514941 200842232 0.058 0.7672 3.3825 0.0213 3 0WCM172_X2_1 1 200842459 249212550 −0.1301 0.5492 2.8682 0.0584 3 0WCM172_X2_1 10 255953 135440117 −0.2418 0.4175 1.74 0.9313 2 1WCM172_X2_1 11 193112 79133220 −0.0106 0.6882 1.7342 1.4885 2 1WCM172_X2_1 11 81601786 84245693 −0.5804 0.0056 NA NA NA NA WCM172_X2_111 84634139 134856574 0.0131 0.7156 1.68 1.6043 2 2 WCM172_X2_1 12148639 33532891 −0.445 0.1729 2.1948 0.0599 2 0 WCM172_X2_1 12 3353812349724853 −0.6873 −0.1291 1.7784 0.0504 2 0 WCM172_X2_1 12 4972509149906650 −0.4038 0.2231 NA NA NA NA WCM172_X2_1 12 49908354 972546200.1231 0.8416 1.8165 1.7675 2 2 WCM172_X2_1 12 97301389 100955712−0.6313 −0.0581 NA NA NA NA WCM172_X2_1 12 100957179 121758192 0.00470.7058 1.6593 1.6028 2 2 WCM172_X2_1 12 122064924 133810926 −0.627−0.0527 1.8772 0.0511 2 0 WCM172_X2_1 13 19600515 24243208 −0.247 0.41141.7407 0.9192 2 1 WCM172_X2_1 13 24304501 88327790 −0.782 −0.2509 1.64290.0379 2 0 WCM172_X2_1 13 88327974 101881814 0.18 0.9062 1.9506 1.7976 22 WCM172_X2_1 13 101910874 115089411 −0.6928 −0.1361 1.715 0.1049 2 0WCM172_X2_1 14 19377697 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1WCM172_X2_1 17 21203893 81083455 0.2573 0.9935 2.0067 1.9753 2 2WCM172_X2_1 18 49022 78005224 0.1755 0.9011 1.8823 1.8527 2 2WCM172_X2_1 19 281499 18547178 −0.4497 0.1672 2.1621 0.0836 2 0WCM172_X2_1 19 18547507 31048071 0.1546 0.8775 2.0125 1.6618 2 2WCM172_X2_1 19 31767480 35502443 −0.4925 0.1147 2.081 0.0845 2 0WCM172_X2_1 19 35504167 37211397 0.2215 0.9532 2.0389 1.8334 2 2WCM172_X2_1 19 37211517 50655886 −0.4134 0.2115 2.2306 0.0851 2 0WCM172_X2_1 19 50657885 59083988 0.0747 0.7863 2.404 1.0454 2 1WCM172_X2_1 2 41609 100360602 −0.232 0.4292 1.6275 1.0655 2 1WCM172_X2_1 2 100368748 103335652 0.2772 1.016 2.9357 1.1088 3 1WCM172_X2_1 2 103340208 111408315 −0.0542 0.6377 NA NA NA NA WCM172_X2_12 111411035 145182370 −0.5251 0.0745 1.0764 1.0295 1 1 WCM172_X2_1 2145187370 151343916 −1.1317 −0.7234 NA NA NA NA WCM172_X2_1 2 151857850172666765 −0.1526 0.5228 1.8348 1.0387 2 1 WCM172_X2_1 2 172669928175202000 −1.1904 −0.8069 NA NA NA NA WCM172_X2_1 2 175213297 184022202−0.1237 0.5567 1.9149 1.0269 2 1 WCM172_X2_1 2 184023082 2349259800.2694 1.0072 2.0326 1.9874 2 2 WCM172_X2_1 2 234959435 240834686−0.4714 0.1406 2.2126 −0.0079 2 0 WCM172_X2_1 2 240882476 242572846−0.0308 0.6648 2.0626 1.1082 2 1 WCM172_X2_1 2 242573114 242946616−0.427 0.1949 NA NA NA NA WCM172_X2_1 20 68363 62904881 0.2375 0.97121.9605 1.9605 2 2 WCM172_X2_1 21 9826207 48084226 0.3405 1.0869 2.18582.0624 2 2 WCM172_X2_1 22 16287437 50320941 −0.0598 0.6312 1.8996 1.19812 1 WCM172_X2_1 22 50355176 51215124 −0.9657 −0.494 1.2938 0.1264 1 0WCM172_X2_1 3 239350 93629510 0.358 1.1064 2.6409 1.6653 3 2 WCM172_X2_13 93643108 127788325 −0.221 0.4423 2.6522 0.0653 3 0 WCM172_X2_1 3127800229 168542702 0.3823 1.1335 2.5556 1.8322 3 2 WCM172_X2_1 3168546914 195956827 0.9638 1.7685 5.0381 1.776 5 2 WCM172_X2_1 3195959323 197894719 −0.7303 −0.1841 1.66 0.1004 2 0 WCM172_X2_1 4 5939417636697 0.1995 0.9283 1.9397 1.8665 2 2 WCM172_X2_1 4 17638206 740270400.0608 0.7704 1.7273 1.6842 2 2 WCM172_X2_1 4 74043189 190426502 0.18840.9158 2.1194 1.6537 2 2 WCM172_X2_1 5 140532 55034800 −0.239 0.42091.7105 0.967 2 1 WCM172_X2_1 5 55038000 115833029 −0.706 −0.1529 1.7270.0718 2 0 WCM172_X2_1 5 115837962 131726445 0.0803 0.7927 1.9285 1.5362 2 WCM172_X2_1 5 131728263 132939664 −0.758 −0.2197 NA NA NA NAWCM172_X2_1 5 133292650 134989582 0.0467 0.7542 NA NA NA NA WCM172_X2_15 135170558 137476428 −0.6076 −0.0284 1.8702 0.0909 2 0 WCM172_X2_1 5137481513 140085334 −0.0021 0.698 1.6916 1.553 2 2 WCM172_X2_1 5140166824 143200053 −0.8144 −0.293 1.569 0.0635 2 0 WCM172_X2_1 5143538036 169361700 0.1107 0.8275 1.7908 1.7584 2 2 WCM172_X2_1 5169410122 174178761 −0.6421 −0.0717 NA NA NA NA WCM172_X2_1 5 174869014180687776 0.1277 0.8468 1.9828 1.6141 2 2 WCM172_X2_1 6 203515 407514−0.1474 0.529 NA NA NA NA WCM172_X2_1 6 486679 13807193 −0.2863 0.36461.7103 0.8647 2 1 WCM172_X2_1 6 13814338 22570496 −0.6925 −0.1357 1.6330.1874 2 0 WCM172_X2_1 6 24134663 82462292 0.0068 0.7083 1.7638 1.5038 22 WCM172_X2_1 6 82881145 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9 130455534141111414 0.0481 0.7558 1.7273 1.6498 2 2 WCM172_X2_1 X 2700119 47486962−0.2064 0.4595 NA NA NA NA WCM172_X2_1 X 47487606 154509348 0.50561.2702 NA NA NA NA WCM176 1 14907 249213973 0.0562 NA NA NA NA NA WCM17610 226083 135438991 0.0511 NA NA NA NA NA WCM176 11 193112 1343205160.0406 NA NA NA NA NA WCM176 12 148465 133810703 0.0319 NA NA NA NA NAWCM176 13 19042005 115089411 0.0251 NA NA NA NA NA WCM176 14 19110349107283270 0.034 NA NA NA NA NA WCM176 15 20083896 102514170 0.0522 NA NANA NA NA WCM176 16 66882 90234899 0.0223 NA NA NA NA NA WCM176 17 13159581187855 0.0303 NA NA NA NA NA WCM176 18 47708 78005274 0.0307 NA NA NANA NA WCM176 19 105021 59093696 −0.0308 NA NA NA NA NA WCM176 2 41620243037022 0.0361 NA NA NA NA NA WCM176 20 68340 62934592 0.0624 NA NA NANA NA WCM176 21 9590314 48084198 0.0248 NA NA NA NA NA WCM176 2216159060 51216336 0.0936 NA NA NA NA NA WCM176 3 239349 197896724 0.0357NA NA NA NA NA WCM176 4 53435 190903980 0.0332 NA NA NA NA NA WCM176 590750 180687821 0.0266 NA NA NA NA NA WCM176 6 203466 170892873 0.0307NA NA NA NA NA WCM176 7 193245 158937158 0.0292 NA NA NA NA NA WCM176 8163457 146279390 0.0191 NA NA NA NA NA WCM176 9 116800 141107536 0.0557NA NA NA NA NA WCM176 X 2700125 154493609 −0.2993 NA NA NA NA NAWCM176_Z1_1 1 69610 82459717 0.0418 −0.011 1.0031 0.9816 1 1 WCM176_Z1_11 84335658 107599765 −0.6887 −0.9526 1.0398 −0.0064 1 0 WCM176_Z1_1 1107599970 249212354 0.0523 0.0015 1.0107 0.9914 1 1 WCM176_Z1_1 10225995 87628923 0.0686 0.0211 1.0245 1.005 1 1 WCM176_Z1_1 10 8789862289269470 −0.6543 −0.9047 NA NA NA NA WCM176_Z1_1 10 89280886 90122349−2.3104 −5.0762 NA NA NA NA WCM176_Z1_1 10 90332716 96313960 −0.6931−0.9587 0.9907 0.0383 1 0 WCM176_Z1_1 10 96316943 135381727 0.06870.0213 1.0405 0.9893 1 1 WCM176_Z1_1 11 193112 19261653 0.0627 0.01411.022 0.9977 1 1 WCM176_Z1_1 11 19372553 20419168 −0.7091 −0.9812 NA NANA NA WCM176_Z1_1 11 20424525 106810318 0.063 0.0145 1.0247 0.9955 1 1WCM176_Z1_1 11 106810789 122968641 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NA NA WCM176_Z1_1 2 178077593 242946616 0.0455−0.0067 1.005 0.9858 1 1 WCM176_Z1_1 20 68363 62904932 0.0301 −0.02530.9909 0.9743 1 1 WCM176_Z1_1 21 9907310 48084277 0.0325 −0.0223 1.00370.9656 1 1 WCM176_Z1_1 22 17063476 51215157 0.0191 −0.0385 0.9866 0.96071 1 WCM176_Z1_1 3 239524 197894719 0.0385 −0.0151 0.9991 0.98 1 1WCM176_Z1_1 4 59331 15018876 0.0641 0.0158 1.0329 0.9891 1 1 WCM176_Z1_14 15042102 44724171 −0.6679 −0.9236 1.0425 0.0119 1 0 WCM176_Z1_1 446053591 105393505 0.0613 0.0124 1.0207 0.9965 1 1 WCM176_Z1_1 4105412061 107845325 −0.6217 −0.8598 NA NA NA NA WCM176_Z1_1 4 107845722118006173 0.0622 0.0135 1.0689 0.9499 1 1 WCM176_Z1_1 4 118006317138453077 −0.6272 −0.8674 1.085 0.0113 1 0 WCM176_Z1_1 4 139100434175252660 0.0651 0.017 1.0325 0.9912 1 1 WCM176_Z1_1 4 175344986178897031 −0.6948 −0.9612 1.0511 −0.0238 1 0 WCM176_Z1_1 4 178911657190426502 0.0624 0.0138 1.0679 0.9513 1 1 WCM176_Z1_1 5 140448 27534090.042 −0.0109 1.0487 0.9362 1 1 WCM176_Z1_1 5 2755166 5489412 −0.7325−1.0142 NA NA NA NA WCM176_Z1_1 5 6312525 64595822 0.0725 0.0259 1.03640.9998 1 1 WCM176_Z1_1 5 64625302 81614091 −0.6886 −0.9525 1.0204 0.01311 0 WCM176_Z1_1 5 82352930 98115828 0.0645 0.0163 1.0503 0.9724 1 1WCM176_Z1_1 5 98128892 98240642 −1.9783 −3.4686 NA NA NA NA WCM176_Z1_15 99715473 101834445 −0.6751 −0.9336 NA NA NA NA WCM176_Z1_1 5 102201966180687814 0.0764 0.0305 1.0324 1.0103 1 1 WCM176_Z1_1 6 203708 66498640.0404 −0.0128 1.0594 0.923 1 1 WCM176_Z1_1 6 6654856 9977777 −0.7155−0.9901 1.0113 −0.0044 1 0 WCM176_Z1_1 6 10393779 73814985 0.0504−7.00E−04 1.0091 0.9899 1 1 WCM176_Z1_1 6 73821042 127607935 −0.6852−0.9477 1.0377 −9.00E−04  1 0 WCM176_Z1_1 6 127608082 129649548 0.05820.0087 NA NA NA NA WCM176_Z1_1 6 129670483 129764207 −0.9363 −1.3115 NANA NA NA WCM176_Z1_1 6 129766885 170893435 0.0643 0.016 1.0403 0.982 1 1WCM176_Z1_1 7 193253 48964707 0.0505 −6.00E−04 1.0152 0.9839 1 1WCM176_Z1_1 7 48965266 53104078 −0.6601 −0.9129 1.0934 −0.0311 1 0WCM176_Z1_1 7 54612356 158937400 0.0678 0.0202 1.036 0.9921 1 1WCM176_Z1_1 8 190906 146279475 0.056 0.006 1.015 0.9933 1 1 WCM176_Z1_19 116832 6015279 0.0561 0.0061 NA NA NA NA WCM176_Z1_1 9 624171221481451 −0.6786 −0.9385 1.0427 8.00E−04 1 0 WCM176_Z1_1 9 2151212624545918 −2.0474 −3.7078 NA NA NA NA WCM176_Z1_1 9 25677782 27949335−0.6723 −0.9297 NA NA NA NA WCM176_Z1_1 9 27949506 141111414 0.05580.0058 1.0149 0.9932 1 1 WCM176_Z1_1 X 2712633 154509348 0.0187 −0.039NA NA NA NA WCM183 1 14930 16865953 −0.4962 0.0638 2.0368 0.0537 2 0WCM183 1 16890598 17250991 −0.7439 −0.3517 1.2724 0.2948 1 0 WCM183 117256433 22850960 −0.4559 0.1271 2.1134 0.0708 2 0 WCM183 1 2285279665068581 −0.1514 0.578 1.8971 1.0885 2 1 WCM183 1 65095054 75055696−0.4971 0.0623 1.0441 1.0441 1 1 WCM183 1 75065485 85511022 −0.15340.5752 1.8431 1.1366 2 1 WCM183 1 85537522 91967454 −0.5293 0.01091.0076 1.0076 1 1 WCM183 1 91973516 115537286 −0.1765 0.5425 1.84971.0633 2 1 WCM183 1 115537869 151553583 0.0901 0.908 1.884 1.869 2 2WCM183 1 151554137 154926249 0.4047 1.3121 2.5791 2.3871 3 2 WCM183 1154930410 155451162 0.2339 1.0959 2.2283 2.0468 2 2 WCM183 1 155451288158450576 −0.4608 0.1195 2.0957 0.077 2 0 WCM183 1 158507184 2120025900.1852 1.0329 2.0461 2.0461 2 2 WCM183 1 212002684 215751313 −0.49820.0606 2.0993 −0.0135 2 0 WCM183 1 215752370 249214018 0.1508 0.98811.9836 1.9836 2 2 WCM183 10 225938 30750519 −0.5388 −0.0044 1.95640.0375 2 0 WCM183 10 30807392 39011152 0.124 0.9529 1.9892 1.8822 2 2WCM183 10 42681235 52603945 −0.4294 0.1683 2.1692 0.0783 2 0 WCM183 1052610365 135477898 0.1102 0.9347 1.9115 1.9115 2 2 WCM183 11 19311220104762 −0.1147 0.6295 1.9574 1.1366 2 1 WCM183 11 20112353 47266288−0.4764 0.095 1.0681 1.0681 1 1 WCM183 11 47266439 49533487 −0.13930.595 1.8651 1.1559 2 1 WCM183 11 49597812 82564202 0.0823 0.8977 1.86311.8631 2 2 WCM183 11 82571081 111614149 −0.1112 0.6344 1.9636 1.1409 2 1WCM183 11 111614263 120278450 −0.4796 0.09 1.0643 1.0643 1 1 WCM183 11120280188 134605817 −0.1217 0.6197 1.9879 1.0852 2 1 WCM183 12 1484279099034 0.0897 0.9075 1.8758 1.8758 2 2 WCM183 12 9142297 25101862−0.5937 −0.0942 1.8247 0.0488 2 0 WCM183 12 25147248 67691593 0.07740.8911 1.8546 1.8546 2 2 WCM183 12 67692761 68054306 0.3445 1.2366 NA NANA NA WCM183 12 68054525 85255668 0.4953 1.4242 3.2375 2.1299 3 2 WCM18312 85257368 133810874 0.2776 1.1519 3.3956 1.0483 3 1 WCM183 13 1904193728794548 0.1255 0.9549 1.9461 1.9308 2 2 WCM183 13 28813807 80911621−0.5158 0.0324 2.0238 0.0217 2 0 WCM183 13 80911750 115089411 0.13730.9704 1.9594 1.9594 2 2 WCM183 14 19110298 61518612 0.1033 0.92551.8994 1.8994 2 2 WCM183 14 61518769 97411378 −0.1297 0.6085 1.93091.1186 2 1 WCM183 14 97411602 107283269 0.1757 1.0206 2.0287 2.0287 2 2WCM183 15 20083896 37390395 −0.1233 0.6175 1.9615 1.1069 2 1 WCM183 1537391675 45360464 −0.5048 0.05 2.0242 0.0464 2 0 WCM183 15 45361166102506273 −0.1333 0.6035 1.9502 1.0887 2 1 WCM183 16 64396 493133480.1243 0.9533 1.9362 1.9362 2 2 WCM183 16 49313526 78133986 −0.5369−0.0014 1.9759 0.0222 2 0 WCM183 16 78142332 90168697 0.1437 0.97881.9708 1.9708 2 2 WCM183 17 131595 21081505 −0.1691 0.553 1.8623 1.07192 1 WCM183 17 21087080 81187845 0.1259 0.9554 1.9392 1.9392 2 2 WCM18318 47607 78005197 −0.1407 0.5931 1.9115 1.1054 2 1 WCM183 19 1050418553924 −0.1615 0.5637 1.8754 1.0808 2 1 WCM183 19 8555078 374419800.1079 0.9317 1.9075 1.9075 2 2 WCM183 19 37464375 59093696 −0.15160.5778 1.8926 1.0925 2 1 WCM183 2 41509 16747054 0.1011 0.9226 1.89551.8955 2 2 WCM183 2 16769307 25377002 −0.1271 0.6122 1.7856 1.2716 2 1WCM183 2 25377265 36774348 0.1336 0.9654 1.9527 1.9527 2 2 WCM183 236775533 39988500 −0.1952 0.5158 1.8179 1.0417 2 1 WCM183 2 3999316740670651 −0.0276 0.7498 NA NA NA NA WCM183 2 41823623 49510173 −0.51730.0301 2.0047 0.0374 2 0 WCM183 2 50106501 51259342 0.2472 1.1129 NA NANA NA WCM183 2 51662287 64751619 −0.6046 −0.1123 1.8402 0.01 2 0 WCM1832 64778706 68480319 −0.1088 0.6378 1.8965 1.2155 2 1 WCM183 2 6848330577747048 0.1415 0.9758 1.9668 1.9668 2 2 WCM183 2 77748891 888855340.3644 1.2617 2.5123 2.2834 3 2 WCM183 2 88885602 97031593 0.1521 0.98982.0613 1.9105 2 2 WCM183 2 97032943 116548640 −0.1467 0.5847 1.83351.1659 2 1 WCM183 2 116572572 133066879 −0.5116 0.0392 1.9937 0.0613 2 0WCM183 2 133070556 133175426 0.0316 0.83 1.8637 1.6916 2 2 WCM183 2133281690 134884753 −1.9884 NA NA NA NA NA WCM183 2 135011869 138434696−0.5099 0.042 2.0084 0.0506 2 0 WCM183 2 138435203 138772143 −1.8363−4.572 NA NA NA NA WCM183 2 139307742 142012147 −0.4207 0.1818 2.25940.0091 2 0 WCM183 2 142238113 239033901 −0.1137 0.6309 1.8857 1.2114 2 1WCM183 2 239034076 243037091 0.2306 1.0917 2.9791 1.2833 3 1 WCM183 2068337 62959285 0.169 1.0119 2.0165 2.0165 2 2 WCM183 21 9590305 480842140.1157 0.9419 1.9211 1.9211 2 2 WCM183 22 16159046 38879562 0.18591.0338 2.0474 2.0474 2 2 WCM183 22 38880092 51115065 −0.1657 0.55781.8681 1.0759 2 1 WCM183 22 51117137 51223730 0.0596 0.8675 NA NA NA NAWCM183 3 239472 47165993 0.4374 1.3528 2.5541 2.5541 3 3 WCM183 347168108 57743471 −0.1094 0.6369 2.0102 1.0997 2 1 WCM183 3 5781726679582217 0.3404 1.2316 2.5822 2.1143 3 2 WCM183 3 79610945 995146290.0611 0.8694 1.8782 1.7757 2 2 WCM183 3 99514776 119886023 −0.13340.6033 1.9243 1.1141 2 1 WCM183 3 119886306 124114050 0.1787 1.02442.0342 2.0342 2 2 WCM183 3 124114560 137484312 0.4803 1.4058 2.70512.5942 3 3 WCM183 3 137717678 195508387 0.7206 1.6964 4.2197 2.262 4 2WCM183 3 195509052 197896705 0.5388 1.4776 3.5765 1.9931 4 2 WCM183 453344 52938243 −0.1517 0.5776 1.8924 1.0924 2 1 WCM183 4 5294297661529800 0.1646 1.0061 2.0084 2.0084 2 2 WCM183 4 62066709 105412852−0.1284 0.6104 1.8604 1.1929 2 1 WCM183 4 106155087 178897062 0.1861.034 2.0477 2.0477 2 2 WCM183 4 178911676 190878582 −0.1772 0.54151.834 1.077 2 1 WCM183 5 90684 10761154 −0.1259 0.6138 1.869 1.1917 2 1WCM183 5 10972012 45645593 0.1273 0.9572 1.9415 1.9415 2 2 WCM183 545695914 52405567 −0.5636 −0.0447 NA NA NA NA WCM183 5 52778714 582856080.1273 0.9572 1.9415 1.9415 2 2 WCM183 5 58285786 83362298 −0.17410.5458 1.8537 1.066 2 1 WCM183 5 83402668 101774480 −0.5981 −0.10151.8652 −0.0011 2 0 WCM183 5 101794080 109065224 −1.9304 −10.5279 0.0534−0.0521 0 0 WCM183 5 109091146 112128141 −0.5779 −0.0681 1.9473 −0.03942 0 WCM183 5 112137014 112164713 −1.8235 −4.3854 NA NA NA NA WCM183 5112170629 112222759 −0.4629 0.1162 NA NA NA NA WCM183 5 112222891112257908 −1.7604 −3.6913 NA NA NA NA WCM183 5 112312528 121726778−0.5668 −0.0499 1.9544 −0.0224 2 0 WCM183 5 121736703 180687808 0.14990.9869 1.9819 1.9819 2 2 WCM183 6 203466 7559668 0.104 0.9265 2.8130.9882 3 1 WCM183 6 7562866 41765419 −0.1823 0.5343 1.8398 1.0566 2 1WCM183 6 41765587 66115283 0.1557 0.9945 1.9924 1.9924 2 2 WCM183 666200400 97051569 −0.5334 0.0043 1.9693 0.0367 2 0 WCM183 6 97051660120336327 −0.1732 0.5472 2.8571 0.0653 3 0 WCM183 6 121401995 1217707140.3162 1.2009 2.6308 1.9669 3 2 WCM183 6 122720841 127476429 −0.14160.5919 2.8811 0.1334 3 0 WCM183 6 127476634 154431565 0.387 1.29 2.56152.3291 3 2 WCM183 6 154439865 165690063 0.096 0.9159 1.8867 1.8867 2 2WCM183 6 165693624 170892848 0.3262 1.2137 2.3662 2.2723 2 2 WCM183 7193253 8792598 −0.4748 0.0976 1.0868 1.0532 1 1 WCM183 7 965460711022012 0.4141 1.3239 NA NA NA NA WCM183 7 11022392 24849598 0.39031.2941 3.6355 1.2691 4 1 WCM183 7 24854765 43283513 0.2198 1.0777 2.9361.2855 3 1 WCM183 7 43351320 53861130 0.4459 1.3633 2.6747 2.4708 3 2WCM183 7 53879272 75988025 0.1764 1.0214 2.0669 1.9929 2 2 WCM183 776018802 94937446 0.36 1.2562 2.8148 1.9624 3 2 WCM183 7 9494080195167113 0.246 1.1114 NA NA NA NA WCM183 7 95213059 103629730 0.13730.9704 2.0134 1.9053 2 2 WCM183 7 103766940 128446479 −0.1588 0.56751.8339 1.1301 2 1 WCM183 7 128446905 158937203 0.1513 0.9886 1.98431.9843 2 2 WCM183 8 163432 27204931 −0.5186 0.0281 1.9959 0.0434 2 0WCM183 8 27255232 56962567 0.1205 0.9483 1.9296 1.9296 2 2 WCM183 856982316 69243580 −0.1341 0.6024 1.5971 1.4394 2 1 WCM183 8 6935178969730485 0.0422 0.8442 NA NA NA NA WCM183 8 69730697 75617961 0.35571.2508 3.6217 1.1378 4 1 WCM183 8 75737595 76402304 −1.2571 −1.4518 NANA NA NA WCM183 8 76452313 76698796 0.4089 1.3174 NA NA NA NA WCM183 877593626 79717166 −1.0698 −0.9965 NA NA NA NA WCM183 8 80549046 815553680.1582 0.9977 NA NA NA NA WCM183 8 81557185 90796265 0.4077 1.31593.7523 1.2269 4 1 WCM183 8 90798879 113267681 0.7247 1.7013 5.308 1.19585 1 WCM183 8 113275894 127564852 0.9297 1.9418 6.4837 1.2002 6 1 WCM1838 127565184 146203769 1.0803 2.1151 6.5376 2.1267 7 2 WCM183 8 146220279146279368 0.1008 0.9222 NA NA NA NA WCM183 9 14867 9766911 −0.1585 0.5681.8366 1.1283 2 1 WCM183 9 12694079 33342786 −0.4954 0.0651 1.04611.0461 1 1 WCM183 9 33344104 78547260 −0.141 0.5926 1.9152 1.1008 2 1WCM183 9 78601032 141107539 0.1415 0.9758 2.8438 1.0897 3 1 WCM183 X2700156 10535265 0.2168 1.0738 NA NA NA NA WCM183 X 10588654 31241136−0.4759 0.0958 NA NA NA NA WCM183 X 31279075 154507335 0.1994 1.0513 NANA NA NA WCM183_Z4_1 1 69603 16774618 −0.8205 0.0697 2.0414 0.0576 2 0WCM183_Z4_1 1 16775691 17296801 −0.6229 0.2746 1.5225 0.8968 2 1WCM183_Z4_1 1 17297200 22852746 −0.7991 0.092 2.087 0.0447 2 0WCM183_Z4_1 1 22895820 64698324 −0.3046 0.6027 2.0272 1.0099 2 1WCM183_Z4_1 1 64707356 75055585 −0.8391 0.0504 1.1724 0.8988 1 1WCM183_Z4_1 1 75065394 85547006 −0.3348 0.5717 1.8973 1.0753 2 1WCM183_Z4_1 1 85548079 91851307 −0.8645 0.024 1.1501 0.8834 1 1WCM183_Z4_1 1 91859761 115829271 −0.3181 0.5889 1.957 1.0512 2 1WCM183_Z4_1 1 116194051 151506526 0.0877 1.0045 2.2089 1.8035 2 2WCM183_Z4_1 1 151507566 155452212 0.3931 1.3155 3.0685 1.9094 3 2WCM183_Z4_1 1 155490984 158450552 −0.8303 0.0595 2.0349 0.0494 2 0WCM183_Z4_1 1 158507184 212002477 0.0902 1.007 2.0241 1.9954 2 2WCM183_Z4_1 1 212115362 215741053 −0.8156 0.0749 2.065 0.0415 2 0WCM183_Z4_1 1 215747180 249212354 0.0855 1.0022 2.0132 1.9928 2 2WCM183_Z4_1 10 226016 30748399 −0.8534 0.0355 1.9913 0.0586 2 0WCM183_Z4_1 10 30749763 39147119 0.0358 0.9515 2.0821 1.7857 2 2WCM183_Z4_1 10 42905578 53059393 −0.8348 0.0549 2.0069 0.0707 2 0WCM183_Z4_1 10 53227568 134699362 0.0526 0.9686 1.9569 1.9569 2 2WCM183_Z4_1 10 134705908 135087709 −0.3005 0.6069 2.0268 1.0192 2 1WCM183_Z4_1 10 135088309 135440105 −0.3444 0.5619 1.9907 0.9616 2 1WCM183_Z4_1 11 193112 47203976 −0.8033 0.0876 1.1907 0.9345 1 1WCM183_Z4_1 11 47204270 48346791 −0.2719 0.6364 1.9151 1.1937 2 1WCM183_Z4_1 11 48347067 56431977 −0.0353 0.8788 2.0457 1.632 2 2WCM183_Z4_1 11 56467926 78516507 0.3868 1.3092 2.9517 2.0043 3 2WCM183_Z4_1 11 78523167 110007479 0.0811 0.9978 2.9815 1.0123 3 1WCM183_Z4_1 11 110007857 111635566 −0.3339 0.5727 NA NA NA NAWCM183_Z4_1 11 111706902 131530906 −0.8157 0.0748 1.0762 1.0302 1 1WCM183_Z4_1 11 132016197 134856498 −0.2787 0.6294 NA NA NA NAWCM183_Z4_1 12 148811 9147765 0.0869 1.0036 2.0357 1.9743 2 2WCM183_Z4_1 12 9161648 25101865 −0.827 0.063 2.0516 0.0376 2 0WCM183_Z4_1 12 25147250 67688883 0.0811 0.9977 2.0152 1.9785 2 2WCM183_Z4_1 12 67691075 72164395 0.3545 1.2764 2.92 1.9245 3 2WCM183_Z4_1 12 72167794 85255675 0.3266 1.2479 2.9526 1.7974 3 2WCM183_Z4_1 12 85260923 133733253 0.078 0.9946 2.9445 1.0405 3 1WCM183_Z4_1 12 133733526 133810735 0.1971 1.1161 NA NA NA NA WCM183_Z4_113 19600515 28794416 0.0581 0.9742 2.0208 1.9084 2 2 WCM183_Z4_1 1328813807 82264468 −0.8262 0.0638 2.0169 0.0735 2 0 WCM183_Z4_1 1382264533 115089411 0.0931 1.01 2.0386 1.9892 2 2 WCM183_Z4_1 14 1937771663174760 0.0748 0.9913 2.0083 1.9677 2 2 WCM183_Z4_1 14 6317500798444438 −0.2921 0.6156 2.0107 1.0538 2 1 WCM183_Z4_1 14 99182569107283027 0.1142 1.0315 2.0838 2.0045 2 2 WCM183_Z4_1 15 2017002826260619 −0.2532 0.6555 2.1282 1.0222 2 1 WCM183_Z4_1 15 2679303345951336 −0.8224 0.0678 2.0257 0.0706 2 0 WCM183_Z4_1 15 45954219102506282 −0.2911 0.6167 3.0138 0.0528 3 0 WCM183_Z4_1 16 66953 486437970.0995 1.0166 2.0437 2.0024 2 2 WCM183_Z4_1 16 49193569 78085854 −0.82120.0691 2.0503 0.0478 2 0 WCM183_Z4_1 16 78133757 90162178 0.0887 1.00552.0077 2.0077 2 2 WCM183_Z4_1 17 131595 21215537 −0.2955 0.6121 1.9651.092 2 1 WCM183_Z4_1 17 21216846 45050443 0.0949 1.0118 2.0618 1.9712 22 WCM183_Z4_1 17 45056177 81083455 0.4004 1.323 2.9774 2.0262 3 2WCM183_Z4_1 18 48247 78005201 −0.3053 0.602 2.02 1.0157 2 1 WCM183_Z4_119 281498 37660744 0.0935 1.0103 2.035 1.9938 2 2 WCM183_Z4_1 1937676251 59083951 −0.2883 0.6195 2.0319 1.0409 2 1 WCM183_Z4_1 2 4160911721146 −0.291 0.6168 2.0894 0.9774 2 1 WCM183_Z4_1 2 11725320 406573780.0819 0.9985 2.0265 1.9694 2 2 WCM183_Z4_1 2 42165742 49510173 −0.83760.052 1.9931 0.0802 2 0 WCM183_Z4_1 2 50149331 53832013 0.0513 0.9673 NANA NA NA WCM183_Z4_1 2 53897735 64685492 −0.8461 0.0431 2.0466 0.0141 20 WCM183_Z4_1 2 64778623 65593739 0.1324 1.0501 2.1361 2.0051 2 2WCM183_Z4_1 2 65604767 88895343 0.3981 1.3207 3.0133 1.9823 3 2WCM183_Z4_1 2 88913369 116548918 0.0823 0.9989 2.0454 1.9516 2 2WCM183_Z4_1 2 116572408 133175429 −0.831 0.0588 2.023 0.0602 2 0WCM183_Z4_1 2 133403772 134884754 −3.7835 −3.3469 NA NA NA NAWCM183_Z4_1 2 135012032 142012149 −0.8281 0.0619 2.037 0.0506 2 0WCM183_Z4_1 2 142237996 239079602 0.0704 0.9868 2.002 1.9615 2 2WCM183_Z4_1 2 239090708 242946607 0.404 1.3267 3.0131 2.0034 3 2WCM183_Z4_1 20 68363 10035223 0.0905 1.0073 2.0614 1.9588 2 2WCM183_Z4_1 20 10036202 14307161 −0.2999 0.6076 NA NA NA NA WCM183_Z4_120 14307388 37601243 0.1198 1.0373 2.0858 2.0188 2 2 WCM183_Z4_1 2037612399 37667181 −0.872 0.0162 NA NA NA NA WCM183_Z4_1 20 3931658162904848 0.112 1.0292 2.041 2.041 2 2 WCM183_Z4_1 21 9826205 480842110.0817 0.9983 2.018 1.9773 2 2 WCM183_Z4_1 22 16287443 39267726 0.09881.0157 2.0426 2.0013 2 2 WCM183_Z4_1 22 39353704 51215138 −0.2853 0.62262.0521 1.0273 2 1 WCM183_Z4_1 3 239347 3084004 0.3389 1.2605 NA NA NA NAWCM183_Z4_1 3 3084747 9066960 0.6307 1.5568 3.0017 2.8823 3 3WCM183_Z4_1 3 9068649 47165118 0.388 1.3104 2.9845 1.9758 3 2WCM183_Z4_1 3 47165651 57678597 −0.286 0.6219 2.0478 1.03 2 1WCM183_Z4_1 3 57743550 79639015 0.3658 1.2879 2.916 1.9673 3 2WCM183_Z4_1 3 81539611 81792714 −0.947 −0.062 NA NA NA NA WCM183_Z4_1 381810770 98600581 −0.056 0.8576 2.027 1.597 2 2 WCM183_Z4_1 3 98620161119962621 −0.3258 0.581 1.9956 0.9962 2 1 WCM183_Z4_1 3 119962869124193571 0.0885 1.0053 2.0914 1.9234 2 2 WCM183_Z4_1 3 124196174137484072 0.394 1.3165 2.9362 2.0449 3 2 WCM183_Z4_1 3 137484257197894713 0.625 1.5511 3.9557 1.905 4 2 WCM183_Z4_1 4 59339 52960717−0.3141 0.593 1.9888 1.0278 2 1 WCM183_Z4_1 4 53463887 57907033 0.35751.2794 3.0249 1.8299 3 2 WCM183_Z4_1 4 57976292 102269630 0.0702 0.98662.0199 1.943 2 2 WCM183_Z4_1 4 102269801 103978998 0.2954 1.2162 NA NANA NA WCM183_Z4_1 4 103987659 104027377 −0.9997 −0.117 NA NA NA NAWCM183_Z4_1 4 104030207 104079831 0.2955 1.2162 NA NA NA NA WCM183_Z4_14 104080281 108615102 0.5945 1.5201 NA NA NA NA WCM183_Z4_1 4 108622411118005832 0.3408 1.2624 NA NA NA NA WCM183_Z4_1 4 118006183 1262426790.6 1.5257 2.9873 2.7711 3 3 WCM183_Z4_1 4 126315100 126337716 −0.24660.6623 NA NA NA NA WCM183_Z4_1 4 126355420 178911657 0.6395 1.56583.0264 2.8943 3 3 WCM183_Z4_1 4 183090510 190426471 0.08 0.9966 3.00980.9809 3 1 WCM183_Z4_1 5 140532 11903945 −0.3016 0.6058 2.0128 1.0309 21 WCM183_Z4_1 5 13692093 45645328 0.0796 0.9962 2.0274 1.9622 2 2WCM183_Z4_1 5 45695964 52900714 −0.7653 0.1271 NA NA NA NA WCM183_Z4_1 552942197 58021861 0.0748 0.9913 2.1422 1.8337 2 2 WCM183_Z4_1 5 5812093183549998 −0.3092 0.598 1.9522 1.075 2 1 WCM183_Z4_1 5 83680169 101774388−0.9033 −0.0164 1.9613 0.016 2 0 WCM183_Z4_1 5 101811461 109049411−3.2844 −2.6793 NA NA NA NA WCM183_Z4_1 5 109091107 121518257 −0.86180.0268 2.0197 0.0177 2 0 WCM183_Z4_1 5 121726864 180687769 0.0785 0.99512.0115 1.9749 2 2 WCM183_Z4_1 6 203588 8428236 0.0591 0.9753 3.02410.908 3 1 WCM183_Z4_1 6 8430049 41721696 −0.3021 0.6054 2.0293 1.0134 21 WCM183_Z4_1 6 41738429 50810865 0.0972 1.0142 2.0672 1.9723 2 2WCM183_Z4_1 6 51483949 55113575 0.3372 1.2587 2.4463 2.3392 2 2WCM183_Z4_1 6 55120051 66115210 0.0984 1.0154 2.0958 1.9472 2 2WCM183_Z4_1 6 66200507 97001296 −0.8624 0.0261 1.9902 0.0463 2 0WCM183_Z4_1 6 97051527 127471675 −0.316 0.591 2.9753 0.0373 3 0WCM183_Z4_1 6 127476490 143655236 0.3845 1.3068 2.8236 2.1243 3 2WCM183_Z4_1 6 143656207 153323820 0.0764 0.9929 3.0447 0.9357 3 1WCM183_Z4_1 6 153332748 165715270 −0.287 0.6208 2.108 0.9676 2 1WCM183_Z4_1 6 165715556 170893427 0.3106 1.2317 2.7045 1.9923 3 2WCM183_Z4_1 7 193451 8196529 −0.2798 0.6283 2.0997 0.9917 2 1WCM183_Z4_1 7 8196810 51261169 0.3825 1.3048 2.9252 2.0158 3 2WCM183_Z4_1 7 51287453 69064936 0.0833 1 2.0775 1.9224 2 2 WCM183_Z4_1 769364361 94919406 0.3649 1.2869 2.9017 1.9785 3 2 WCM183_Z4_1 7 94928327103389942 0.0988 1.0158 2.0963 1.9478 2 2 WCM183_Z4_1 7 103393636158937400 −0.2952 0.6124 2.0063 1.0514 2 1 WCM183_Z4_1 8 190906 27204941−0.4027 0.5018 2.7717 0.0604 3 0 WCM183_Z4_1 8 27255276 69730480 0.34231.2639 2.7924 2.0106 3 2 WCM183_Z4_1 8 70476335 75272466 0.8077 1.7362NA NA NA NA WCM183_Z4_1 8 75274141 76476254 0.2562 1.1763 NA NA NA NAWCM183_Z4_1 8 77616564 79717152 −0.3701 0.5355 NA NA NA NA WCM183_Z4_1 880523445 89340141 0.806 1.7345 3.4523 3.203 3 3 WCM183_Z4_1 8 90770353113237068 1.1568 2.0892 5.7503 2.7598 6 3 WCM183_Z4_1 8 113241088146279475 1.336 2.27 6.7545 2.8918 7 3 WCM183_Z4_1 9 17101 8733788 −0.310.5972 1.9651 1.0604 2 1 WCM183_Z4_1 9 12694075 32987821 −0.8586 0.03011.1592 0.8829 1 1 WCM183_Z4_1 9 32988129 78686806 −0.2996 0.6079 1.95461.0935 2 1 WCM183_Z4_1 9 78710991 141111414 0.0859 1.0026 2.9731 1.03413 1 WCM183_Z4_1 X 2707682 10535466 0.0641 0.9804 NA NA NA NA WCM183_Z4_1X 11130185 31279075 −0.8632 0.0253 NA NA NA NA WCM183_Z4_1 X 31284937154509348 0.0437 0.9595 NA NA NA NA WCM185 1 17484 249213973 −0.0128 NANA NA NA NA WCM185 10 225936 135438983 −0.0244 NA NA NA NA NA WCM185 11193112 134605916 −0.0303 NA NA NA NA NA WCM185 12 148444 133810868−0.0384 NA NA NA NA NA WCM185 13 19041992 115089411 −0.0449 NA NA NA NANA WCM185 14 19110239 107283184 −0.0427 NA NA NA NA NA WCM185 1520083897 102514189 −0.0092 NA NA NA NA NA WCM185 16 67688 90168687−0.058 NA NA NA NA NA WCM185 17 131595 81052563 −0.0285 NA NA NA NA NAWCM185 18 47732 78005164 −0.0253 NA NA NA NA NA WCM185 19 10508059093645 −0.0105 NA NA NA NA NA WCM185 2 41463 243036958 −0.0228 NA NANA NA NA WCM185 20 68342 62934617 −1.00E−04 NA NA NA NA NA WCM185 219590311 48084201 −0.0337 NA NA NA NA NA WCM185 22 16159016 51193629−0.0032 NA NA NA NA NA WCM185 3 239472 197896724 −0.0339 NA NA NA NA NAWCM185 4 53360 190878508 −0.0593 NA NA NA NA NA WCM185 5 90714 180687827−0.0308 NA NA NA NA NA WCM185 6 203424 170892848 −0.057 NA NA NA NA NAWCM185 7 193253 158937161 −0.0024 NA NA NA NA NA WCM185 8 190879146279480 −0.0485 NA NA NA NA NA WCM185 9 116874 141071646 0.0096 NA NANA NA NA WCM185 X 2700139 154490227 −0.0771 NA NA NA NA NA WCM185-TP1 117459 215808056 −0.1144 0.0209 1.0146 1.0146 1 1 WCM185-TP1 1 215812492243595136 −0.3443 −2.7772 0.1459 0.1459 0 0 WCM185-TP1 1 243651876249213961 −0.0242 0.4803 1.395 1.395 1 1 WCM185-TP1 10 226106 135439032−0.0957 0.1264 1.0916 1.0916 1 1 WCM185-TP1 11 193112 134605916 −0.1216−0.0216 0.9852 0.9852 1 1 WCM185-TP1 12 148388 133810788 −0.1158 0.01281.0089 1.0089 1 1 WCM185-TP1 13 19041992 115089411 −0.1178 0.0011 1.00081.0008 1 1 WCM185-TP1 14 19110394 107283210 −0.1104 0.0439 1.0309 1.03091 1 WCM185-TP1 15 20083887 25277789  8.00E−04 0.5897 1.7732 1.2367 2 1WCM185-TP1 15 25287053 25599532 1.4144 3.6009 NA NA NA NA WCM185-TP1 1525599815 102514230 −0.0853 0.1827 1.135 1.135 1 1 WCM185-TP1 16 6768672156908 −0.1261 −0.0481 0.9672 0.9672 1 1 WCM185-TP1 16 7215754488932017 −0.3456 −2.8199 0.3376 −0.0543 0 0 WCM185-TP1 16 8894121490168697 −0.2258 −0.7949 1.1659 −0.0132 1 0 WCM185-TP1 17 13159581052563 −0.1158 0.0128 1.0089 1.0089 1 1 WCM185-TP1 18 47672 78005140−0.1362 −0.1104 0.9263 0.9263 1 1 WCM185-TP1 19 105050 8982261 −0.138−0.1221 0.9189 0.9189 1 1 WCM185-TP1 19 8986999 9768797 0.3797 1.77553.4236 3.4236 3 3 WCM185-TP1 19 9770173 11687908 −0.1806 −0.4149 0.75010.7501 1 1 WCM185-TP1 19 11708361 12754426 0.7157 2.4859 5.6018 5.6018 66 WCM185-TP1 19 12754621 19773917 −0.161 −0.2736 0.8273 0.8273 1 1WCM185-TP1 19 19779736 24310467 0.7496 2.5486 5.8508 5.8508 6 6WCM185-TP1 19 24310774 43023330 −0.0724 0.2498 1.1891 1.1891 1 1WCM185-TP1 19 43025383 43780550 1.3262 3.4756 11.9406 10.308 12  10 WCM185-TP1 19 43858026 52794481 −0.0846 0.1863 1.1378 1.1378 1 1WCM185-TP1 19 52795443 54265726 0.7123 2.4795 5.577 5.577 6 6 WCM185-TP119 54290959 59093696 0.0341 0.7258 1.6539 1.6539 2 2 WCM185-TP1 2 41623116600728 −0.0789 0.216 1.1615 1.1615 1 1 WCM185-TP1 2 116601631151326761 −0.3189 −2.0882 0.4092 0.0612 0 0 WCM185-TP1 2 151328247243036958 −0.1139 0.0237 1.0166 1.0166 1 1 WCM185-TP1 20 68346 62934623−0.1191 −0.0067 0.9953 0.9953 1 1 WCM185-TP1 21 9590305 48084175 −0.09130.1506 1.11 1.11 1 1 WCM185-TP1 22 16159068 51193629 −0.0554 0.33461.2611 1.2611 1 1 WCM185-TP1 3 239472 197896724 −0.1065 0.0666 1.04731.0473 1 1 WCM185-TP1 4 53360 190878479 −0.1214 −0.0199 0.9863 0.9863 11 WCM185-TP1 5 90750 180687824 −0.1098 0.0477 1.0336 1.0336 1 1WCM185-TP1 6 203479 66005970 −0.1104 0.0443 1.0312 1.0312 1 1 WCM185-TP16 66006023 126329584 −0.3688 −4.0283 0.0613 0.0613 0 0 WCM185-TP1 6126332349 170892848 −0.1439 −0.1594 0.8954 0.8954 1 1 WCM185-TP1 7193222 158937135 0.0724 0.8716 1.8297 1.8297 2 2 WCM185-TP1 8 1908783165420 −0.1523 −0.2143 0.862 0.862 1 1 WCM185-TP1 8 3165934 35563495−0.3393 −2.6115 0.1636 0.1636 0 0 WCM185-TP1 8 35579010 146279498−0.0524 0.3492 1.2738 1.2738 1 1 WCM185-TP1 9 116918 141071646 0.00720.6165 1.5331 1.5331 2 2 WCM185-TP1 X 2700122 154490187 −0.0835 0.1922NA NA NA NA WCM185-TP2 1 17483 6605097 0.0032 0.1046 1.0752 1.0752 1 1WCM185-TP2 1 6605205 60297867 −0.1647 −0.1165 0.9224 0.9224 1 1WCM185-TP2 1 60299038 152104268 −0.0728 0.0055 1.0038 1.0038 1 1WCM185-TP2 1 152127221 153122563 0.6665 0.9162 1.8871 1.8871 2 2WCM185-TP2 1 153177276 185278583 −0.0867 −0.0128 0.9912 0.9912 1 1WCM185-TP2 1 185703968 196762536 −0.7244 −0.9317 0.9602 0.0883 1 0WCM185-TP2 1 196763797 215808069 −0.0209 0.0734 1.0522 1.0522 1 1WCM185-TP2 1 215812492 243289756 −0.7235 −0.9302 0.9795 0.07 1 0WCM185-TP2 1 243292633 249213973 −0.0315 0.0596 1.0422 1.0422 1 1WCM185-TP2 10 225995 135438967 −0.0716 0.0072 1.005 1.005 1 1 WCM185-TP211 193112 134605916 −0.1091 −0.0424 0.971 0.971 1 1 WCM185-TP2 12 148417133810832 −0.1109 −0.0447 0.9695 0.9695 1 1 WCM185-TP2 13 19041937115089411 −0.0862 −0.0121 0.9917 0.9917 1 1 WCM185-TP2 14 19110394107283228 −0.0966 −0.0258 0.9823 0.9823 1 1 WCM185-TP2 15 2008388925287053 0.0396 0.1515 1.1863 1.0351 1 1 WCM185-TP2 15 25296693 254959731.5249 1.879 NA NA NA NA WCM185-TP2 15 25514900 102514230 −0.0837−0.0089 0.9939 0.9939 1 1 WCM185-TP2 16 67688 72184720 −0.1167 −0.05250.9642 0.9642 1 1 WCM185-TP2 16 72188278 90128558 −0.7445 −0.964 0.97410.0512 1 0 WCM185-TP2 16 90128812 90168694 −0.1228 −0.0605 NA NA NA NAWCM185-TP2 17 131595 563578 −0.1653 −0.1174 NA NA NA NA WCM185-TP2 17565054 14110317 −0.5413 −0.6485 0.6866 0.5893 1 1 WCM185-TP2 17 1413957281052563 −0.1048 −0.0367 0.9749 0.9749 1 1 WCM185-TP2 18 47808 25646481−0.0511 0.034 1.0239 1.0239 1 1 WCM185-TP2 18 25727739 78005197 −0.4135−0.4614 0.7648 0.6877 1 1 WCM185-TP2 19 105021 2538224 −0.1129 −0.04740.9741 0.9613 1 1 WCM185-TP2 19 2538668 3985327 −0.7086 −0.9064 0.92080.1462 1 0 WCM185-TP2 19 4013115 8982193 −0.1197 −0.0565 0.9616 0.9616 11 WCM185-TP2 19 8987037 9869186 0.4323 0.6388 1.5571 1.5571 2 2WCM185-TP2 19 9869378 11687372 −0.2109 −0.179 0.8833 0.8833 1 1WCM185-TP2 19 11687629 12754375 0.6722 0.9228 1.8958 1.8958 2 2WCM185-TP2 19 12754621 19773929 −0.1514 −0.0988 0.9338 0.9338 1 1WCM185-TP2 19 19779759 24310198 0.8067 1.0786 2.112 2.112 2 2 WCM185-TP219 24310535 43016600 −0.0992 −0.0293 0.9799 0.9799 1 1 WCM185-TP2 1943023114 43780474 1.2674 1.5971 3.1791 2.8717 3 3 WCM185-TP2 19 4385804652772856 −0.1204 −0.0573 0.961 0.961 1 1 WCM185-TP2 19 52780808 542990790.7019 0.9575 1.9419 1.9419 2 2 WCM185-TP2 19 54299338 59093645 0.05020.1651 1.1213 1.1213 1 1 WCM185-TP2 2 41614 88999476 −0.0867 −0.01280.9912 0.9912 1 1 WCM185-TP2 2 89034134 96648067 0.5495 0.7787 1.79681.6343 2 2 WCM185-TP2 2 96652502 116601864 −0.0298 0.0618 1.0438 1.04381 1 WCM185-TP2 2 118572355 148705796 −0.6733 −0.8506 0.9906 0.1185 1 0WCM185-TP2 2 148710008 243037004 −0.088 −0.0146 0.99 0.99 1 1 WCM185-TP220 68397 62934541 −0.0708 0.0081 1.0057 1.0057 1 1 WCM185-TP2 21 959031448084226 −0.0859 −0.0118 0.9919 0.9919 1 1 WCM185-TP2 22 1615907951193629 −0.0844 −0.0097 0.9933 0.9933 1 1 WCM185-TP2 3 239472 197896724−0.0768  3.00E−04 1.0002 1.0002 1 1 WCM185-TP2 4 53360 172735860 −0.1044−0.0362 0.9752 0.9752 1 1 WCM185-TP2 4 172761121 190878508 −0.735−0.9487 0.9442 0.092 1 0 WCM185-TP2 5 90714 840342 −0.4971 −0.58291.1957 0.1395 1 0 WCM185-TP2 5 840575 53247452 0.0428 0.1556 1.11391.1139 1 1 WCM185-TP2 5 53362913 55063722 −0.6394 −0.7978 0.9602 0.19031 0 WCM185-TP2 5 55075867 58470295 −2.0846 −6.4512 0.0314 −0.0085 0 0WCM185-TP2 5 58475470 80911313 −0.5599 −0.6764 1.1341 0.1173 1 0WCM185-TP2 5 80932452 86707209 −0.0195 0.0752 1.1206 0.9864 1 1WCM185-TP2 5 86708647 102894868 −0.5669 −0.6871 1.1486 0.0936 1 0WCM185-TP2 5 102895139 131731248 −0.0629 0.0185 1.0129 1.0129 1 1WCM185-TP2 5 131755651 133640258 −0.7897 −1.0378 0.972 0.0021 1 0WCM185-TP2 5 133642261 180687830 −0.1084 −0.0415 0.9716 0.9716 1 1WCM185-TP2 6 203428 69348629 −0.1278 −0.0672 0.9545 0.9545 1 1WCM185-TP2 6 69348824 126342407 −0.7395 −0.956 0.9278 0.1032 1 0WCM185-TP2 6 126349463 170892848 −0.0985 −0.0283 0.9806 0.9806 1 1WCM185-TP2 7 193254 56174230 0.3369 0.5233 1.5021 1.3724 2 1 WCM185-TP27 56358786 65444845 0.9745 1.2699 2.5887 2.2342 3 2 WCM185-TP2 765445312 158937161 0.3047 0.4839 1.4636 1.3333 1 1 WCM185-TP2 8 1908903226783 −0.0869 −0.013 0.991 0.991 1 1 WCM185-TP2 8 3245054 34180923−0.7237 −0.9305 0.9794 0.07 1 0 WCM185-TP2 8 35383173 146279511 0.02350.1309 1.0949 1.0949 1 1 WCM185-TP2 9 116944 141071646 0.1902 0.34231.2678 1.2678 1 1 WCM185-TP2 X 2700189 154490238 −0.0811 −0.0053 NA NANA NA WCM185-TP3 1 17477 152009401 −0.0876 −0.0415 0.9717 0.9717 1 1WCM185-TP3 1 152052152 153177182 0.5987 0.8298 1.7775 1.7775 2 2WCM185-TP3 1 153190794 185277118 −0.0937 −0.0498 0.9661 0.9661 1 1WCM185-TP3 1 185277929 196758777 −0.6518 −0.8798 1.0257 0.0612 1 0WCM185-TP3 1 196762591 215793883 −0.0399 0.0231 1.0161 1.0161 1 1WCM185-TP3 1 215794338 243289748 −0.7222 −0.9977 0.9192 0.0824 1 0WCM185-TP3 1 243292657 249213967 0.0289 0.115 1.0829 1.0829 1 1WCM185-TP3 10 225958 135439027 −0.0549 0.0029 1.002 1.002 1 1 WCM185-TP311 193112 48373815 −0.0642 −0.0097 0.9933 0.9933 1 1 WCM185-TP3 1148387206 55111013 0.4406 0.6384 1.6482 1.465 2 1 WCM185-TP3 11 55111284134605906 −0.1099 −0.0719 0.9514 0.9514 1 1 WCM185-TP3 12 148454133810883 −0.1011 −0.0599 0.9593 0.9593 1 1 WCM185-TP3 13 19042005115089411 −0.073 −0.0216 0.9851 0.9851 1 1 WCM185-TP3 14 19110239107283269 −0.0942 −0.0505 0.9656 0.9656 1 1 WCM185-TP3 15 2008392125277791 0.0849 0.1886 1.2097 1.0696 1 1 WCM185-TP3 15 25287052 255998661.27 1.6036 NA NA NA NA WCM185-TP3 15 25601049 102514189 −0.0698 −0.01740.988 0.988 1 1 WCM185-TP3 16 67699 72188322 −0.0924 −0.048 0.96730.9673 1 1 WCM185-TP3 16 72198706 90103742 −0.7314 −1.0133 0.9146 0.07631 0 WCM185-TP3 16 90104154 90168680 −0.0403 0.0225 NA NA NA NAWCM185-TP3 17 131595 14110179 −0.6757 −0.9194 0.5692 0.4883 1 0WCM185-TP3 17 14139572 81052563 −0.0995 −0.0577 0.9608 0.9608 1 1WCM185-TP3 18 47801 27878947 −0.0634 −0.0086 0.9941 0.9941 1 1WCM185-TP3 18 28571229 78005279 −0.3475 −0.4082 0.7536 0.7536 1 1WCM185-TP3 19 105080 2515096 −0.1197 −0.0854 0.9968 0.8882 1 1WCM185-TP3 19 2520679 3985366 −0.7292 −1.0096 0.9114 0.082 1 0WCM185-TP3 19 4013004 8982204 −0.0494 0.0103 1.0072 1.0072 1 1WCM185-TP3 19 8987030 9080462 0.6632 0.9068 1.8749 1.8749 2 2 WCM185-TP319 9080646 11708361 −0.1027 −0.0621 0.9578 0.9578 1 1 WCM185-TP3 1911725438 12637528 0.6954 0.9449 1.9251 1.9251 2 2 WCM185-TP3 19 1263805619843710 −0.1318 −0.102 0.9317 0.9317 1 1 WCM185-TP3 19 1990531624310193 0.7049 0.9561 1.9401 1.9401 2 2 WCM185-TP3 19 24310487 43015702−0.0391 0.0241 1.0168 1.0168 1 1 WCM185-TP3 19 43016506 43780453 1.24471.5753 2.9801 2.9801 3 3 WCM185-TP3 19 43857931 52887131 −0.0951 −0.05170.9648 0.9648 1 1 WCM185-TP3 19 52887599 54265648 0.7614 1.0227 2.03172.0317 2 2 WCM185-TP3 19 54290991 59093645 0.1217 0.2365 1.1782 1.1782 11 WCM185-TP3 2 41474 88999476 −0.0783 −0.0288 0.9802 0.9802 1 1WCM185-TP3 2 89034028 96686913 0.5399 0.7591 1.7783 1.6067 2 2WCM185-TP3 2 96687324 116600767 −0.031 0.035 1.0245 1.0245 1 1WCM185-TP3 2 116601631 148730283 −0.6773 −0.922 0.9647 0.0908 1 0WCM185-TP3 2 148731023 243037004 −0.0723 −0.0207 0.9858 0.9858 1 1WCM185-TP3 20 68311 62934623 −0.0791 −0.03 0.9794 0.9794 1 1 WCM185-TP321 9590305 48084181 −0.1015 −0.0605 0.9589 0.9589 1 1 WCM185-TP3 2216159031 51193629 −0.0723 −0.0208 0.9857 0.9857 1 1 WCM185-TP3 3 239472197896711 −0.064 −0.0094 0.9935 0.9935 1 1 WCM185-TP3 4 53360 172735749−0.0698 −0.0173 0.9881 0.9881 1 1 WCM185-TP3 4 172761121 190878508−0.7199 −0.9938 0.9136 0.0908 1 0 WCM185-TP3 5 90684 876309 −0.5423−0.7037 1.1363 0.0917 1 0 WCM185-TP3 5 878475 53362913 0.0051 0.08331.0594 1.0594 1 1 WCM185-TP3 5 53389633 55063758 −0.5704 −0.7481 1.07820.1126 1 0 WCM185-TP3 5 55075944 58571238 −1.9417 −6.0989 0.0354 −0.00630 0 WCM185-TP3 5 58652670 80809502 −0.5967 −0.7902 1.0524 0.1042 1 0WCM185-TP3 5 80911233 86707209 0.0206 0.1039 1.2272 0.9221 1 1WCM185-TP3 5 86708626 102614287 −0.5685 −0.7451 1.0725 0.1207 1 0WCM185-TP3 5 102886605 131731248 −0.0608 −0.0052 0.9964 0.9964 1 1WCM185-TP3 5 131755651 133640210 −0.7609 −1.0642 0.9022 0.0543 1 0WCM185-TP3 5 133642358 180687830 −0.0928 −0.0486 0.9669 0.9669 1 1WCM185-TP3 6 203479 67069279 −0.1008 −0.0595 0.9596 0.9596 1 1WCM185-TP3 6 67859534 126358837 −0.7204 −0.9945 0.9251 0.0787 1 0WCM185-TP3 6 126359931 170892848 −0.0821 −0.034 0.9767 0.9767 1 1WCM185-TP3 7 193222 56358942 0.3618 0.5411 1.5436 1.3666 2 1 WCM185-TP37 56428074 65444853 0.9186 1.2054 2.6701 1.942 3 2 WCM185-TP3 7 65445356158937072 0.3441 0.5192 1.5492 1.3172 2 1 WCM185-TP3 8 190850 32267610.0739 0.1742 1.1284 1.1284 1 1 WCM185-TP3 8 3245054 35563496 −0.7035−0.966 0.9349 0.0889 1 0 WCM185-TP3 8 35579008 146279507 0.1025 0.21161.158 1.158 1 1 WCM185-TP3 9 116815 141071646 0.1236 0.2391 1.18031.1803 1 1 WCM185-TP3 X 2700194 154490194 −0.1347 −0.106 NA NA NA NAWCM185-TP4 1 17465 152104264 −0.0741 NA NA NA NA NA WCM185-TP4 1152127392 153177196 0.6815 NA NA NA NA NA WCM185-TP4 1 153190787249213961 −0.0929 NA NA NA NA NA WCM185-TP4 10 226048 135439021 −0.0702NA NA NA NA NA WCM185-TP4 11 193112 134605906 −0.0892 NA NA NA NA NAWCM185-TP4 12 148567 133810794 −0.0965 NA NA NA NA NA WCM185-TP4 1319042005 115089411 −0.1112 NA NA NA NA NA WCM185-TP4 14 19110394107283203 −0.1017 NA NA NA NA NA WCM185-TP4 15 20083921 102514186 −0.055NA NA NA NA NA WCM185-TP4 16 67688 90168694 −0.1067 NA NA NA NA NAWCM185-TP4 17 131595 81052609 −0.0765 NA NA NA NA NA WCM185-TP4 18 4764778005194 −0.0911 NA NA NA NA NA WCM185-TP4 19 105010 11687372 −0.0516 NANA NA NA NA WCM185-TP4 19 11687630 12637487 0.602 NA NA NA NA NAWCM185-TP4 19 12637883 19824879 −0.1208 NA NA NA NA NA WCM185-TP4 1919825246 24310198 0.5843 NA NA NA NA NA WCM185-TP4 19 24310464 43023366−0.0764 NA NA NA NA NA WCM185-TP4 19 43025535 43780453 1.0716 NA NA NANA NA WCM185-TP4 19 43857954 52919716 −0.0833 NA NA NA NA NA WCM185-TP419 52919981 54265598 0.5703 NA NA NA NA NA WCM185-TP4 19 5429099459093645 0.019 NA NA NA NA NA WCM185-TP4 2 41614 88913273 −0.1012 NA NANA NA NA WCM185-TP4 2 88998020 96795829 0.3926 NA NA NA NA NA WCM185-TP42 96798330 243037116 −0.0737 NA NA NA NA NA WCM185-TP4 20 68312 62934572−0.0764 NA NA NA NA NA WCM185-TP4 21 9590316 48084136 −0.067 NA NA NA NANA WCM185-TP4 22 16159005 51193629 −0.0512 NA NA NA NA NA WCM185-TP4 3239495 197896656 −0.0899 NA NA NA NA NA WCM185-TP4 4 53360 190878508−0.1049 NA NA NA NA NA WCM185-TP4 5 90750 180687830 −0.0735 NA NA NA NANA WCM185-TP4 6 203516 170892848 −0.1308 NA NA NA NA NA WCM185-TP4 7193254 158937158 −0.0516 NA NA NA NA NA WCM185-TP4 8 190877 146279472−0.0906 NA NA NA NA NA WCM185-TP4 9 116800 141071646 −0.0168 NA NA NA NANA WCM185-TP4 X 2700156 154490196 −0.0738 NA NA NA NA NA WCM185_X1_1 1721450 212960903 −0.0142 0.1025 1.1314 1.0159 1 1 WCM185_X1_1 1212964924 247109117 −0.1682 −1.543 0.6675 0.0189 1 0 WCM185_X1_1 1247130152 249212114 −0.0766 −0.3801 0.9342 0.6025 1 1 WCM185_X1_1 10225958 135440080 −0.07 −0.3221 0.8415 0.7582 1 1 WCM185_X1_1 11 193112134856562 −0.0642 −0.2729 0.8834 0.7719 1 1 WCM185_X1_1 12 148673133810713 −0.0707 −0.3279 0.8661 0.7273 1 1 WCM185_X1_1 13 19600159115089411 −0.0098 0.1317 1.1825 1.0088 1 1 WCM185_X1_1 14 19377733107283068 −0.0357 −0.0485 1.0309 0.9029 1 1 WCM185_X1_1 15 20170150102515282 0.0282 0.3663 1.3634 1.2147 1 1 WCM185_X1_1 16 67604 902336270.0276 0.3626 1.8429 0.7286 2 1 WCM185_X1_1 17 131595 81083455 0.0410.4382 1.4074 1.3025 1 1 WCM185_X1_1 18 48965 78005219 0.0058 0.23191.2256 1.1232 1 1 WCM185_X1_1 19 281424 59083923 0.0335 0.3965 1.78620.8464 2 1 WCM185_X1_1 2 41620 242946597 −0.0055 0.1602 1.1683 1.0666 11 WCM185_X1_1 20 68363 62904845 0.0109 0.2634 1.237 1.1636 1 1WCM185_X1_1 21 9826203 48084226 0.008 0.2453 1.2953 1.0754 1 1WCM185_X1_1 22 17063440 51215130 0.0609 0.5453 1.5582 1.3605 2 1WCM185_X1_1 3 239436 197894720 0.0249 0.3473 1.3463 1.198 1 1WCM185_X1_1 4 59383 190426471 −0.0926 −0.5317 0.7532 0.6302 1 1WCM185_X1_1 5 140532 180687769 −0.0935 −0.5402 0.7833 0.5921 1 1WCM185_X1_1 6 203475 170893408 −0.0679 −0.3037 1.13 0.4903 1 0WCM185_X1_1 7 193222 158937400 −0.0295 −0.0035 1.5259 0.4692 2 0WCM185_X1_1 8 190907 146279416 −0.0911 −0.5168 0.7742 0.6237 1 1WCM185_X1_1 9 116819 139395118 −0.0467 −0.1316 0.9551 0.8705 1 1WCM185_X1_1 9 139396338 139397557 −1.9589 NA NA NA NA NA WCM185_X1_1 9139397678 141111414 0.0026 0.2117 1.4282 0.8879 1 1 WCM185_X1_1 X2700156 154509348 −0.0852 −0.4594 NA NA NA NA WCM185_Z1_1 1 721450157069273 −0.0179 −0.0135 0.9968 0.9845 1 1 WCM185_Z1_1 1 157094682157811477 −0.7617 −1.0083 NA NA NA NA WCM185_Z1_1 1 157963503 185278606−0.0134 −0.0079 0.9946 0.9946 1 1 WCM185_Z1_1 1 185703968 196857331−0.7711 −1.0221 1.0092 −0.0245 1 0 WCM185_Z1_1 1 196871717 215821013−0.0063  8.00E−04 1.0006 1.0006 1 1 WCM185_Z1_1 1 215822033 243292679−0.7564 −1.0006 1.0227 −0.0231 1 0 WCM185_Z1_1 1 243327940 249212238−0.0017 0.0066 1.0207 0.9885 1 1 WCM185_Z1_1 10 226016 135440090 −0.0128−0.0072 0.995 0.995 1 1 WCM185_Z1_1 11 193112 134856562 −0.0156 −0.01060.9951 0.9902 1 1 WCM185_Z1_1 12 148673 133810713 −0.0125 −0.0068 1.00270.988 1 1 WCM185_Z1_1 13 19600147 115089411 −0.0026 0.0054 1.0038 1.00381 1 WCM185_Z1_1 14 19377711 36400963 0.0062 0.0163 1.0201 1.0026 1 1WCM185_Z1_1 14 36768359 38152053 0.6282 0.7509 NA NA NA NA WCM185_Z1_114 38165967 107283183 −0.0175 −0.0129 0.9997 0.9825 1 1 WCM185_Z1_1 1520170150 102515266 −0.0177 −0.0132 0.997 0.9848 1 1 WCM185_Z1_1 16 6760472198737 −0.0214 −0.0177 0.9927 0.9829 1 1 WCM185_Z1_1 16 7282120990233626 −0.7527 −0.9951 1.0179 −0.0144 1 0 WCM185_Z1_1 17 13159581083455 −0.0278 −0.0258 0.9908 0.9738 1 1 WCM185_Z1_1 18 49039 78005214−0.012 −0.0062 0.9957 0.9957 1 1 WCM185_Z1_1 19 281506 2576047 −0.0344−0.034 0.9973 0.9561 1 1 WCM185_Z1_1 19 2642971 3984142 −0.8066 −1.07490.9457 0.0037 1 0 WCM185_Z1_1 19 3985379 59083953 −0.0504 −0.0538 0.97060.9562 1 1 WCM185_Z1_1 2 41613 118575215 −0.0081 −0.0014 1.0027 0.9953 11 WCM185_Z1_1 2 118575296 148733472 −0.7577 −1.0024 1.0172 −0.0188 1 0WCM185_Z1_1 2 149220220 242946604 −0.007 0 1.0037 0.9963 1 1 WCM185_Z1_120 68363 62904845 −0.022 −0.0186 0.9933 0.9811 1 1 WCM185_Z1_1 219826207 48084214 −0.0186 −0.0144 0.995 0.9852 1 1 WCM185_Z1_1 2216287508 51215142 −0.0212 −0.0176 0.9977 0.9781 1 1 WCM185_Z1_1 3 239431197894713 −0.0041 0.0036 1.0025 1.0025 1 1 WCM185_Z1_1 4 59390 171010812−0.0048 0.0028 1.0019 1.0019 1 1 WCM185_Z1_1 4 172735897 190426471−0.7622 −1.009 0.995 −0.0012 1 0 WCM185_Z1_1 5 140532 878525 −0.716−0.9415 1.038 0.0033 1 0 WCM185_Z1_1 5 881237 53182522 0.0325 0.04861.0457 1.0229 1 1 WCM185_Z1_1 5 53247347 55062786 −0.7081 −0.93 1.01850.0312 1 0 WCM185_Z1_1 5 55063821 58476464 −2.2118 −4.9115 NA NA NA NAWCM185_Z1_1 5 58481027 80932390 −0.696 −0.9126 1.0841 −0.0217 1 0WCM185_Z1_1 5 81006528 86708587  3.00E−04 0.009 NA NA NA NA WCM185_Z1_15 87486046 102886605 −0.6006 −0.7771 1.1562 0.0109 1 0 WCM185_Z1_1 5102887945 131729935 0.0515 0.0719 1.0704 1.0318 1 1 WCM185_Z1_1 5131755613 133561464 −0.7379 −0.9734 0.9824 0.0362 1 0 WCM185_Z1_1 5133622246 180687800 −0.007 0 1 1 1 1 WCM185_Z1_1 6 203561 66204848−0.0088 −0.0023 1.0071 0.9898 1 1 WCM185_Z1_1 6 66205150 126342320−0.7312 −0.9637 1.0209 0.0046 1 0 WCM185_Z1_1 6 126359850 1708934240.0013 0.0102 1.0071 1.0071 1 1 WCM185_Z1_1 7 193222 1883863 0.46830.5673 1.9846 0.9788 2 1 WCM185_Z1_1 7 1886998 3197867 0.7351 0.87211.9521 1.7085 2 2 WCM185_Z1_1 7 3205705 158937400 0.4808 0.5818 2.00570.9877 2 1 WCM185_Z1_1 8 190907 3226824 −0.0789 −0.0894 0.9399 0.9399 11 WCM185_Z1_1 8 3245054 33454987 −0.7407 −0.9775 1.0402 −0.0245 1 0WCM185_Z1_1 8 35407004 146279514 −0.0088 −0.0023 1.0034 0.9935 1 1WCM185_Z1_1 9 116800 141111414 0.0042 0.0138 1.0096 1.0096 1 1WCM185_Z1_1 X 2700159 154509348 −0.0322 −0.0312 NA NA NA NA WCM192 117462 249213961 −0.0119 NA NA NA NA NA WCM192 10 225988 135438982−0.0803 NA NA NA NA NA WCM192 11 193112 134605954 −0.0104 NA NA NA NA NAWCM192 12 148468 133810855 −0.0394 NA NA NA NA NA WCM192 13 19041994115089411 −0.0543 NA NA NA NA NA WCM192 14 19110231 107283255 −0.0189 NANA NA NA NA WCM192 15 20083889 102514230 −0.0056 NA NA NA NA NA WCM19216 67570 90168646 −0.0699 NA NA NA NA NA WCM192 17 131595 81052551−0.0552 NA NA NA NA NA WCM192 18 47797 78005210 −0.0078 NA NA NA NA NAWCM192 19 105021 59093696 0.0652 NA NA NA NA NA WCM192 2 41675 101564763−0.0071 NA NA NA NA NA WCM192 2 101566016 179665386 −0.1094 NA NA NA NANA WCM192 2 179667035 243037013 0.0018 NA NA NA NA NA WCM192 20 6841362934617 0.011 NA NA NA NA NA WCM192 21 9590312 48084214 −0.0206 NA NANA NA NA WCM192 22 16159043 51219089 −0.0027 NA NA NA NA NA WCM192 3239443 197896789 −0.0152 NA NA NA NA NA WCM192 4 53359 190878479 −0.0541NA NA NA NA NA WCM192 5 90647 180687828 −0.0122 NA NA NA NA NA WCM192 6203364 170892873 −0.0267 NA NA NA NA NA WCM192 7 193171 158937161 0.0029NA NA NA NA NA WCM192 8 163527 146279545 −0.0093 NA NA NA NA NA WCM192 914876 37917268 −0.0985 NA NA NA NA NA WCM192 9 37919096 141107533 0.1113NA NA NA NA NA WCM192 X 2700122 154509348 −0.0294 NA NA NA NA NAWCM192_X1_1 1 721476 5940243 0.0791 0.0602 1.0613 1.0239 1 1 WCM192_X1_11 5947386 21377390 −0.7432 −0.9982 0.998 0.0033 1 0 WCM192_X1_1 121415705 43300813 −0.0364 −0.0792 0.9719 0.9212 1 1 WCM192_X1_1 143304641 176132049 0.1147 0.1027 1.1594 0.9881 1 1 WCM192_X1_1 1176132997 207135760 −0.0331 −0.0751 0.9735 0.925 1 1 WCM192_X1_1 1207135828 229795037 −0.4866 −0.6485 0.9692 0.3067 1 0 WCM192_X1_1 1230314032 249212348 0.1161 0.1043 1.1032 1.0469 1 1 WCM192_X1_1 10226016 16918997 −0.2555 −0.3504 1.6301 −0.0614 2 0 WCM192_X1_1 1016930461 47680417 −0.5054 −0.6733 0.9282 0.3259 1 0 WCM192_X1_1 1047681735 106160501 −0.7457 −1.0017 0.9776 0.0212 1 0 WCM192_X1_1 10106163516 128147658 −0.5275 −0.7028 1.2288 0 1 0 WCM192_X1_1 10128147884 135440108 −0.7523 −1.011 0.9477 0.0447 1 0 WCM192_X1_1 11193112 134856611 −0.0624 −0.1109 1.0108 0.8412 1 1 WCM192_X1_1 12 1486443982475 −0.1042 −0.162 0.8971 0.8905 1 1 WCM192_X1_1 12 4383239 26878682−0.7849 −1.0573 0.9726 −0.0116 1 0 WCM192_X1_1 12 26943134 38714877−0.0798 −0.1321 0.9337 0.8913 1 1 WCM192_X1_1 12 39047754 456958320.3887 0.4235 1.74 0.9423 2 1 WCM192_X1_1 12 45740843 52754667 −0.8235−1.1126 0.9229 0.002 1 0 WCM192_X1_1 12 52755248 118693368 −0.0326−0.0745 1.0466 0.8527 1 1 WCM192_X1_1 12 118814556 120568537 −0.7942−1.0705 NA NA NA NA WCM192_X1_1 12 120569025 133810735 −0.0874 −0.14140.9222 0.8911 1 1 WCM192_X1_1 13 19600365 30524481 −0.8056 −1.08680.9187 0.0229 1 0 WCM192_X1_1 13 30782858 46137837 −0.0399 −0.08341.0105 0.8772 1 1 WCM192_X1_1 13 46142549 61103114 −0.6165 −0.82271.1685 −0.0377 1 0 WCM192_X1_1 13 61109310 115089411 0.0899 0.0731 1.0961.008 1 1 WCM192_X1_1 14 19377726 107283060 0.1141 0.1019 1.1716 0.97481 1 WCM192_X1_1 15 20170156 76452462 0.0845 0.0667 1.0598 1.0348 1 1WCM192_X1_1 15 76463463 102517667 −0.6658 −0.8902 1.0405 0.0386 1 0WCM192_X1_1 16 67604 46513110 0.1 0.0851 1.1582 0.9633 1 1 WCM192_X1_116 46532030 67042966 −0.6586 −0.8803 1.0818 0.0046 1 0 WCM192_X1_1 1667063379 67261122 −2.1219 −3.9112 NA NA NA NA WCM192_X1_1 16 6726173990233642 −0.6439 −0.8602 1.0859 0.0158 1 0 WCM192_X1_1 17 131595 44422350.5741 0.6352 2.1333 0.9731 2 1 WCM192_X1_1 17 4442835 21826220 0.09070.074 1.0627 1.0426 1 1 WCM192_X1_1 17 22023461 29326175 −0.6436 −0.85981.167 −0.065 1 0 WCM192_X1_1 17 29483072 61905539 −0.2738 −0.3735 1.53770.0062 2 0 WCM192_X1_1 17 61906846 62084040 −1.8644 −3.0651 NA NA NA NAWCM192_X1_1 17 62121480 81083507 −0.2763 −0.3767 1.5131 0.0272 2 0WCM192_X1_1 18 48266 33484792 0.1484 0.1427 1.1524 1.0555 1 1WCM192_X1_1 18 33552709 39535310 −0.6827 −0.9137 NA NA NA NA WCM192_X1_118 39537555 78005203 0.1038 0.0897 1.087 1.0413 1 1 WCM192_X1_1 19281405 2123376 −0.0623 −0.1107 1.1331 0.7192 1 1 WCM192_X1_1 19 212386330193878 0.1307 0.1217 1.2121 0.9639 1 1 WCM192_X1_1 19 3019919742603713 0.5773 0.6389 2.054 1.0602 2 1 WCM192_X1_1 19 42603950 43430860−1.9977 −3.46 NA NA NA NA WCM192_X1_1 19 43433805 44739303 0.0435 0.01752.0722 −0.0478 2 0 WCM192_X1_1 19 44739399 58790713 0.5876 0.6505 2.09491.0444 2 1 WCM192_X1_1 19 58790978 59083968 −0.5777 −0.77 1.1822 −0.00941 0 WCM192_X1_1 2 41613 99198091 0.1095 0.0965 1.0844 1.0539 1 1WCM192_X1_1 2 99204069 176957969 −0.634 −0.8465 1.1337 −0.0214 1 0WCM192_X1_1 2 176958139 225761065 0.1254 0.1154 1.1168 1.0498 1 1WCM192_X1_1 2 225781443 229890400 −0.6571 −0.8783 1.0577 0.0303 1 0WCM192_X1_1 2 229890656 233470873 0.0835 0.0654 1.0789 1.0139 1 1WCM192_X1_1 2 233498564 237276918 −0.3984 −0.533 1.0217 0.3605 1 0WCM192_X1_1 2 237285764 238785909 0.027 −0.0024 NA NA NA NA WCM192_X1_12 238820208 239140843 −0.6598 −0.8819 NA NA NA NA WCM192_X1_1 2239147655 242946616 0.0253 −0.0044 1.0498 0.9441 1 1 WCM192_X1_1 2068406 61945519 0.1058 0.092 1.1129 1.0189 1 1 WCM192_X1_1 20 6194677862904863 0.9753 1.0819 3.0083 1.2253 3 1 WCM192_X1_1 21 9826235 480842140.06 0.0373 1.0459 1.0065 1 1 WCM192_X1_1 22 16287446 39104945 0.10320.0889 1.0813 1.0458 1 1 WCM192_X1_1 22 39111928 51214212 −0.6473−0.8649 1.0565 0.0417 1 0 WCM192_X1_1 3 239611 111870336 0.1012 0.08651.1606 0.963 1 1 WCM192_X1_1 3 111870767 126452028 −0.6348 −0.8477 1.12−0.0086 1 0 WCM192_X1_1 3 126571570 197894726 0.1165 0.1048 1.16110.9896 1 1 WCM192_X1_1 4 59385 24556419 0.0543 0.0304 1.0507 0.9919 1 1WCM192_X1_1 4 24557921 28364204 −0.8091 −1.092 NA NA NA NA WCM192_X1_1 428372367 78871010 −0.0477 −0.0929 0.9559 0.9193 1 1 WCM192_X1_1 478979202 91832492 −0.7392 −0.9925 1.0084 −0.0032 1 0 WCM192_X1_1 491839399 115997565 −0.3847 −0.5153 1.4088 −0.0095 1 0 WCM192_X1_1 4115997938 146092838 −0.7908 −1.0658 0.9883 −0.0328 1 0 WCM192_X1_1 4146095863 185552305 −0.4644 −0.6192 0.9292 0.3729 1 0 WCM192_X1_1 4185552952 190426570 −0.7457 −1.0017 0.96 0.0388 1 0 WCM192_X1_1 5 14053235641648 −0.0888 −0.1432 0.9255 0.8855 1 1 WCM192_X1_1 5 3564686338528924 −0.7444 −0.9999 NA NA NA NA WCM192_X1_1 5 38530749 90678841−0.0696 −0.1196 0.9486 0.8923 1 1 WCM192_X1_1 5 92921014 120022354−0.7711 −1.0377 1.0019 −0.0277 1 0 WCM192_X1_1 5 121187718 124036846−0.1015 −0.1587 NA NA NA NA WCM192_X1_1 5 124044430 169017781 0.36580.397 1.6866 0.9471 2 1 WCM192_X1_1 5 169018159 170149739 −0.087 −0.1409NA NA NA NA WCM192_X1_1 5 170159801 172196074 0.3866 0.421 NA NA NA NAWCM192_X1_1 5 172196672 180687768 −0.1307 −0.1947 1.7851 −0.0376 2 0WCM192_X1_1 6 203516 43970447 −0.1006 −0.1577 0.9141 0.8789 1 1WCM192_X1_1 6 43970827 46133178 −0.838 −1.1337 0.9862 −0.0747 1 0WCM192_X1_1 6 46135347 170893450 −0.0489 −0.0944 1.0246 0.8488 1 1WCM192_X1_1 7 193265 158937046 −0.0796 −0.1319 1.0501 0.7752 1 1WCM192_X1_1 8 190906 146279527 −0.0631 −0.1118 1.0543 0.7966 1 1WCM192_X1_1 9 116854 28888879 −0.7032 −0.9421 1.0601 −0.0191 1 0WCM192_X1_1 9 32384732 35243312 −0.1626 −0.2342 0.8881 0.8122 1 1WCM192_X1_1 9 35259018 35676179 −0.9673 −1.3251 NA NA NA NA WCM192_X1_19 35677794 36223427 −0.1048 −0.1628 NA NA NA NA WCM192_X1_1 9 3622727136669402 0.2041 0.2085 NA NA NA NA WCM192_X1_1 9 36671094 75773677 0−0.035 1.0209 0.9312 1 1 WCM192_X1_1 9 75774304 141111414 0.4099 0.44791.7986 0.9295 2 1 WCM192_X1_1 X 2700146 154509348 −0.0213 −0.0608 NA NANA NA WCM192_Z1_1 1 721415 5965831 −0.0085 0.7126 2.247 1.0305 2 1WCM192_Z1_1 1 5967259 6184092 −0.3487 −0.0712 NA NA NA NA WCM192_Z1_1 16184592 22174426 −0.2962 0.0669 2.0896 0.0053 2 0 WCM192_Z1_1 1 2217451822181215 −0.1615 0.3892 NA NA NA NA WCM192_Z1_1 1 22181420 23645104−0.0653 0.5968 1.7545 1.2703 2 1 WCM192_Z1_1 1 23650078 35454501 −0.3573−0.0947 0.975 0.8979 1 1 WCM192_Z1_1 1 35457747 35480334 0.297 1.269 NANA NA NA WCM192_Z1_1 1 35480677 204434438 0.0047 0.7388 2.276 1.0615 2 1WCM192_Z1_1 1 204435934 228582508 0.0767 0.8779 1.8863 1.7891 2 2WCM192_Z1_1 1 228582706 229794992 0.0719 0.8687 NA NA NA NA WCM192_Z1_11 230314016 249212348 0.4619 1.5357 3.6425 2.1563 4 2 WCM192_Z1_1 10225952 135440105 −0.2955 0.0688 2.1478 −0.0501 2 0 WCM192_Z1_1 11 193112134856562 −0.0202 0.6892 2.2093 1.0155 2 1 WCM192_Z1_1 12 14867426985684 −0.2466 0.1906 2.217 0.0654 2 0 WCM192_Z1_1 12 2705929339064532 0.0043 0.7381 1.9451 1.3908 2 1 WCM192_Z1_1 12 3907128945664250 0.4755 1.5569 4.9181 0.9664 5 1 WCM192_Z1_1 12 4568670352756206 −0.6149 −0.9533 1.0771 −0.0442 1 0 WCM192_Z1_1 12 52756668118828806 0.0024 0.7343 2.2336 1.0935 2 1 WCM192_Z1_1 12 118829053120569028 −0.3255 −0.0093 NA NA NA NA WCM192_Z1_1 12 120569794 133810905−0.0176 0.6943 2.1251 1.1112 2 1 WCM192_Z1_1 13 19600371 30521813−0.2807 0.1061 2.211 −0.0583 2 0 WCM192_Z1_1 13 30524459 46124385−0.0041 0.7213 2.1801 1.1173 2 1 WCM192_Z1_1 13 46135505 61986918−0.2948 0.0705 2.1094 −0.0092 2 0 WCM192_Z1_1 13 61987202 1150894110.0092 0.7477 2.2651 1.0931 2 1 WCM192_Z1_1 14 19377701 107283027 0.19631.0959 2.1677 2.1073 2 2 WCM192_Z1_1 15 20170091 76254301 −0.3191 0.00761.1661 0.8444 1 1 WCM192_Z1_1 15 76298096 102517678 −0.6146 −0.95181.0885 −0.0545 1 0 WCM192_Z1_1 16 67604 34682253 0.0601 0.8463 2.09971.4961 2 1 WCM192_Z1_1 16 46508214 90233596 −0.4965 −0.5142 1.4394−0.039 1 0 WCM192_Z1_1 17 131595 2203262 0.2434 1.1779 2.2937 2.2314 2 2WCM192_Z1_1 17 2203720 7623163 0.4039 1.4441 3.3956 2.0463 3 2WCM192_Z1_1 17 7626964 10318816 0.1709 1.0509 2.1533 1.9904 2 2WCM192_Z1_1 17 10319022 12823143 0.4783 1.5613 3.7303 2.1721 4 2WCM192_Z1_1 17 12832337 30211465 0.1069 0.9344 1.9714 1.8509 2 2WCM192_Z1_1 17 30213068 81083561 −0.2941 0.0722 2.1781 −0.0755 2 0WCM192_Z1_1 18 48224 1276033 0.1869 1.0793 NA NA NA NA WCM192_Z1_1 181278621 55862847 0.2033 1.1082 2.2013 2.1104 2 2 WCM192_Z1_1 18 5591269278005215 0.0136 0.7563 2.2869 1.0914 2 1 WCM192_Z1_1 19 281503 425998370.1846 1.0752 2.1406 2.0733 2 2 WCM192_Z1_1 19 42600052 42719311 −0.4647−0.4109 NA NA NA NA WCM192_Z1_1 19 42720952 43414882 −1.0721 NA NA NA NANA WCM192_Z1_1 19 43420451 44721988 −0.2974 0.0639 1.9982 0.0923 2 0WCM192_Z1_1 19 44732725 59083923 0.1789 1.0651 2.1295 2.0551 2 2WCM192_Z1_1 2 41623 676630 0.1784 1.0643 NA NA NA NA WCM192_Z1_1 2905302 44502788 0.0772 0.8788 2.1477 1.53 2 2 WCM192_Z1_1 2 4450299299198091 0.1957 1.095 2.1737 2.0984 2 2 WCM192_Z1_1 2 99203972 176945234−0.2959 0.0677 2.0824 0.0137 2 0 WCM192_Z1_1 2 176946914 1898528340.0874 0.898 2.3842 1.3427 2 1 WCM192_Z1_1 2 189853326 226378260 0.01050.7502 2.199 1.1651 2 1 WCM192_Z1_1 2 226378359 228996775 −0.3576−0.0955 2.1837 −0.3119 2 0 WCM192_Z1_1 2 229035210 238903428 0.15531.0228 2.0758 1.9879 2 2 WCM192_Z1_1 2 238934045 239147660 −0.3227−0.0018 NA NA NA NA WCM192_Z1_1 2 239147783 242946597 0.1578 1.02742.097 1.9796 2 2 WCM192_Z1_1 20 68396 61945435 0.1891 1.0833 2.14892.0889 2 2 WCM192_Z1_1 20 61946779 62904866 0.7326 1.939 6.7261 0.9429 71 WCM192_Z1_1 21 9826230 45649494 −0.2638 0.1484 2.1797 0.0371 2 0WCM192_Z1_1 21 45649715 48084207 −0.1533 0.4075 2.1783 0.4745 2 0WCM192_Z1_1 22 16287467 21576187 −0.2908 0.0806 1.1112 1.0037 1 1WCM192_Z1_1 22 21799250 23629349 −0.1609 0.3905 1.3962 1.2255 1 1WCM192_Z1_1 22 23630353 26040629 0.1583 1.0282 2.6452 1.4338 3 1WCM192_Z1_1 22 26057576 30639993 −0.0369 0.6553 1.9661 1.1837 2 1WCM192_Z1_1 22 30640817 32914312 0.1609 1.0329 3.3002 0.792 3 1WCM192_Z1_1 22 32923962 39122435 −0.0194 0.6907 1.9516 1.2765 2 1WCM192_Z1_1 22 39123282 42473441 −0.3228 −0.002 1.9455 0.0518 2 0WCM192_Z1_1 22 42473614 43459885 0.1703 1.0498 3.8953 0.2453 4 0WCM192_Z1_1 22 43460301 49042503 −0.2918 0.0782 1.9935 0.1178 2 0WCM192_Z1_1 22 49089182 51219138 −0.6144 −0.9513 1.0694 −0.0351 1 0WCM192_Z1_1 3 239443 29476406 0.0058 0.741 2.1536 1.1892 2 1 WCM192_Z1_13 29529959 111860122 −0.2774 0.1145 1.1179 1.0474 1 1 WCM192_Z1_1 3111870274 122496628 −0.6291 −1.0133 1.0846 −0.0938 1 0 WCM192_Z1_1 3122512504 126348309 −0.2986 0.0607 2.2519 −0.1659 2 0 WCM192_Z1_1 3126349577 126633582 −0.5023 −0.5337 NA NA NA NA WCM192_Z1_1 3 126645187197894720 0.037 0.8021 2.3815 1.1057 2 1 WCM192_Z1_1 4 59405 71275632−0.1253 0.4692 2.1956 0.5731 2 1 WCM192_Z1_1 4 71339753 190426471−0.2682 0.1375 2.2582 −0.0582 2 0 WCM192_Z1_1 5 140532 35010172 0.22441.1451 2.3192 2.104 2 2 WCM192_Z1_1 5 35013125 43613093 −0.151 0.41261.8318 0.8304 2 1 WCM192_Z1_1 5 43616071 90678832 0.2517 1.1923 2.33212.2381 2 2 WCM192_Z1_1 5 92921008 119800199 −0.2374 0.2127 2.3197 −0.0022 0 WCM192_Z1_1 5 119816974 168690612 0.2077 1.116 2.1864 2.1485 2 2WCM192_Z1_1 5 169015496 169931634 −0.2588 0.1608 NA NA NA NA WCM192_Z1_15 170139864 172096791 0.1538 1.0202 NA NA NA NA WCM192_Z1_1 5 172110465180687768 −0.3021 0.0517 2.0637 0.0093 2 0 WCM192_Z1_1 6 203588 7569463−0.3269 −0.0129 1.3714 0.6108 1 1 WCM192_Z1_1 6 7570685 21065411 −0.04210.6447 2.1481 0.9787 2 1 WCM192_Z1_1 6 21198329 26431826 0.0769 0.87821.8936 1.7826 2 2 WCM192_Z1_1 6 26444331 43028084 0.0366 0.8013 2.01931.4659 2 1 WCM192_Z1_1 6 43029282 170893408 0.1143 0.9482 1.9721 1.88672 2 WCM192_Z1_1 7 193254 76991907 0.0112 0.7517 2.1976 1.1699 2 1WCM192_Z1_1 7 77003457 158663881 0.2088 1.1179 2.2235 2.1171 2 2WCM192_Z1_1 7 158664253 158937072 0.1255 0.9687 NA NA NA NA WCM192_Z1_18 190897 121475938 0.0274 0.7834 2.2476 1.1948 2 1 WCM192_Z1_1 8121483155 146279527 0.2078 1.1162 2.2438 2.0918 2 2 WCM192_Z1_1 9 17079312226 −0.3785 −0.1537 NA NA NA NA WCM192_Z1_1 9 312494 27558505 −0.25450.1713 2.276 −0.0239 2 0 WCM192_Z1_1 9 27560281 75450992 −0.0394 0.65012.1967 0.9419 2 1 WCM192_Z1_1 9 75516125 141111414 0.2121 1.1238 2.2022.1563 2 2 WCM192_Z1_1 X 2700122 154509348 0.1653 1.0409 NA NA NA NAWCM195 1 14930 249213206 0.0343 0.3087 1.2386 1.2386 1 1 WCM195 10226118 135477898 −0.0052 −0.1609 0.8945 0.8945 1 1 WCM195 11 19309662259215 0.0269 0.2311 1.1737 1.1737 1 1 WCM195 11 62283366 67375962−0.1063 −4.1538 0.0562 0.0562 0 0 WCM195 11 67376113 134605916 0.00920.0269 1.0188 1.0188 1 1 WCM195 12 148452 133810752 0.0039 −0.03980.9728 0.9728 1 1 WCM195 13 19041994 115089411 0.0276 0.2389 1.18011.1801 1 1 WCM195 14 19110349 107283156 −0.0121 −0.2585 0.836 0.836 1 1WCM195 15 20083896 102514189 0.0237 0.1955 1.1451 1.1451 1 1 WCM195 1674402 90260461 −0.0087 −0.2095 0.8648 0.8648 1 1 WCM195 17 13159581187934 0.003 −0.0509 0.9654 0.9654 1 1 WCM195 18 47818 78005201 0.01120.0512 1.0361 1.0361 1 1 WCM195 19 105010 59093645 −0.0447 −0.83730.5597 0.5597 1 1 WCM195 2 41620 243052790 −0.0081 −0.2007 0.8701 0.87011 1 WCM195 20 68342 47887791 0.0426 0.3924 1.3125 1.3125 1 1 WCM195 2047887863 47897204 −1.2965 NA NA NA NA NA WCM195 20 47905620 629346230.0111 0.0505 1.0356 1.0356 1 1 WCM195 21 9590407 48084181 −0.0102−0.2309 0.8521 0.8521 1 1 WCM195 22 16159060 51219090 0.013 0.073 1.05191.0519 1 1 WCM195 3 239398 197896740 0.0174 0.1253 1.0907 1.0907 1 1WCM195 4 53340 190903980 −0.0023 −0.121 0.9195 0.9195 1 1 WCM195 5 90684180687854 0.005 −0.0251 0.9827 0.9827 1 1 WCM195 6 203424 170892918−0.0123 −0.262 0.8339 0.8339 1 1 WCM195 7 193222 158937046 0.0149 0.09541.0683 1.0683 1 1 WCM195 8 163476 146279511 0.0169 0.1189 1.0859 1.08591 1 WCM195 9 14884 141107536 0.0452 0.4172 1.3353 1.3353 1 1 WCM195 X2700122 154493590 −0.0701 −1.5169 NA NA NA NA WCM195_Z8_1 1 72147637346317 −0.1043 0.5985 1.9936 1.0347 2 1 WCM195_Z8_1 1 3735667938511660 0.6083 1.3305 3.0387 1.9911 3 2 WCM195_Z8_1 1 38511716 52526164−0.1145 0.5879 2.018 0.9881 2 1 WCM195_Z8_1 1 52530552 52769545 0.71881.4433 NA NA NA NA WCM195_Z8_1 1 52800371 52981585 −0.141 0.5605 NA NANA NA WCM195_Z8_1 1 52991442 59364929 0.6237 1.3463 3.1809 1.9041 3 2WCM195_Z8_1 1 59787414 66458662 −0.1562 0.5447 1.9348 0.9827 2 1WCM195_Z8_1 1 66713293 85279851 0.5612 1.2824 2.8996 1.9652 3 2WCM195_Z8_1 1 85331194 120612037 −0.1283 0.5736 1.9567 1.0198 2 1WCM195_Z8_1 1 143767833 150483355 0.5175 1.2377 3.5829 1.1335 4 1WCM195_Z8_1 1 150483644 150636176 0.6327 1.3554 NA NA NA NA WCM195_Z8_11 150667278 151282710 1.1622 1.894 NA NA NA NA WCM195_Z8_1 1 151288172153751651 0.8041 1.5301 2.9027 2.8733 3 3 WCM195_Z8_1 1 153751870154933456 1.2292 1.9619 5.0646 2.7271 5 3 WCM195_Z8_1 1 154936403156646939 0.8293 1.5558 2.94 2.94 3 3 WCM195_Z8_1 1 156669858 1568437131.2478 1.9808 NA NA NA NA WCM195_Z8_1 1 156844408 157494341 0.856 1.583NA NA NA NA WCM195_Z8_1 1 157497597 159558487 0.2292 0.9423 2.84940.9937 3 1 WCM195_Z8_1 1 159683392 160681485 0.8128 1.539 2.9621 2.84963 3 WCM195_Z8_1 1 160709117 190423813 0.2657 0.9797 2.9095 1.0346 3 1WCM195_Z8_1 1 192128425 192628621 −1.357 −0.7253 NA NA NA NA WCM195_Z8_11 192778247 202574894 0.2434 0.9569 2.8523 1.03 3 1 WCM195_Z8_1 1202698267 203734472 0.797 1.5229 NA NA NA NA WCM195_Z8_1 1 203734755205902157 0.2562 0.9701 2.846 1.0718 3 1 WCM195_Z8_1 1 205904837207627762 0.4247 1.1428 NA NA NA NA WCM195_Z8_1 1 207639933 2113806490.8027 1.5286 3.035 2.7353 3 3 WCM195_Z8_1 1 211381231 214567089 0.30561.0208 NA NA NA NA WCM195_Z8_1 1 214568312 214781685 0.1093 0.8189 NA NANA NA WCM195_Z8_1 1 214782145 242612655 −0.1547 0.5463 2.893 0.0276 3 0WCM195_Z8_1 1 242687390 245849969 0.3404 1.0564 NA NA NA NA WCM195_Z8_11 245850070 247004281 0.8467 1.5734 NA NA NA NA WCM195_Z8_1 1 247007137249212348 0.2514 0.9651 2.8784 1.0259 3 1 WCM195_Z8_1 10 225958135440117 −0.6631 0.0158 1.9789 0.0431 2 0 WCM195_Z8_1 11 19311217868254 −0.1267 0.5753 1.9744 1.0056 2 1 WCM195_Z8_1 11 1794030518655750 −0.662 0.0169 1.941 0.0825 2 0 WCM195_Z8_1 11 18720435 66043540−0.1231 0.579 1.9361 1.0515 2 1 WCM195_Z8_1 11 66045951 66083241 −1.3126−0.6771 NA NA NA NA WCM195_Z8_1 11 66083591 67821513 −0.1229 0.57921.9549 1.0331 2 1 WCM195_Z8_1 11 67829229 68216291 −1.4833 −0.8631 NA NANA NA WCM195_Z8_1 11 68305354 89951324 −0.1155 0.5868 1.9046 1.0993 2 1WCM195_Z8_1 11 89955794 105948544 −1.4994 −0.8808 1.0238 0.0623 1 0WCM195_Z8_1 11 105950296 106856840 −0.495 0.1921 NA NA NA NA WCM195_Z8_111 107197707 108302472 −1.4797 −0.8592 NA NA NA NA WCM195_Z8_1 11108332229 110001831 −0.1848 0.5151 NA NA NA NA WCM195_Z8_1 11 110007543122968504 −1.4919 −0.8725 1.0504 0.042 1 0 WCM195_Z8_1 11 123065642134856489 −0.1255 0.5766 1.9545 1.0281 2 1 WCM195_Z8_1 12 148675 8930211−0.1036 0.5992 2.0258 1.0038 2 1 WCM195_Z8_1 12 8975308 16758746 −1.4483−0.8248 1.0953 0.0338 1 0 WCM195_Z8_1 12 17142102 133810703 −0.12640.5755 1.9732 1.0073 2 1 WCM195_Z8_1 13 19600515 23908034 1.068 1.79846.8679 0.0886 7 0 WCM195_Z8_1 13 23908225 26978129 0.2276 0.9406 3.78880.0499 4 0 WCM195_Z8_1 13 27216479 31543083 −0.1677 0.5329 NA NA NA NAWCM195_Z8_1 13 31711224 37014182 1.4277 2.1629 8.9091 0.047 9 0WCM195_Z8_1 13 37015314 42803258 0.274 0.9883 3.8758 0.092 4 0WCM195_Z8_1 13 42866613 43180895 −1.5001 −0.8815 NA NA NA NA WCM195_Z8_113 43358204 43987026 −0.1601 0.5407 NA NA NA NA WCM195_Z8_1 13 4441156147470930 1.4712 2.2069 9.1652 0.0688 9 0 WCM195_Z8_1 13 4851754050746944 −1.4576 −0.8349 NA NA NA NA WCM195_Z8_1 13 51287361 536248141.3713 2.1058 8.5439 0.065 9 0 WCM195_Z8_1 13 55748609 94680066 −1.4364−0.8118 1.0158 0.1235 1 0 WCM195_Z8_1 13 94938654 97639137 0.4282 1.1464NA NA NA NA WCM195_Z8_1 13 97639403 101944627 1.6339 2.3713 10.28080.0676 10  0 WCM195_Z8_1 13 101997684 107823109 0.3701 1.0869 4.17460.0736 4 0 WCM195_Z8_1 13 107863061 108955933 −1.3898 −0.761 NA NA NA NAWCM195_Z8_1 13 109282197 111303432 1.12 1.8512 7.1809 0.0352 7 0WCM195_Z8_1 13 111315796 115089411 0.2795 0.994 3.9398 0.0434 4 0WCM195_Z8_1 14 19377703 23398410 −0.6231 0.0578 1.9934 0.0884 2 0WCM195_Z8_1 14 23415772 23978555 −0.153 0.5481 NA NA NA NA WCM195_Z8_114 23991261 31058634 −0.6211 0.0599 2.0192 0.0656 2 0 WCM195_Z8_1 1431059942 107283039 −0.1022 0.6007 1.9934 1.0394 2 1 WCM195_Z8_1 1520170150 102517666 −0.1543 0.5467 1.9344 0.9871 2 1 WCM195_Z8_1 16 9743690233601 −0.1228 0.5794 1.9644 1.024 2 1 WCM195_Z8_1 17 131595 18238908−0.6626 0.0163 1.9892 0.0336 2 0 WCM195_Z8_1 17 18243508 22023436−0.6793 −0.0013 1.4429 0.5553 1 1 WCM195_Z8_1 17 25621438 81083567 0.3441.0601 2.085 2.085 2 2 WCM195_Z8_1 18 48241 78005226 −0.1668 0.53371.9082 0.9871 2 1 WCM195_Z8_1 19 281413 59083988 −0.1366 0.565 1.95890.9999 2 1 WCM195_Z8_1 2 41620 242842512 −0.1508 0.5503 1.9347 0.9941 21 WCM195_Z8_1 20 68396 21695425 −0.6394 0.0406 1.0632 0.994 1 1WCM195_Z8_1 20 22562677 26084194 0.2591 0.973 2.9203 1.0055 3 1WCM195_Z8_1 20 26094564 43738633 −0.1346 0.5671 1.8866 1.0766 2 1WCM195_Z8_1 20 43739119 45916015 0.2276 0.9406 1.9194 1.9194 2 2WCM195_Z8_1 20 45918931 62904847 0.5502 1.2711 2.8253 2.0016 3 2WCM195_Z8_1 21 9826230 32537369 −1.4899 −0.8704 1.0765 0.0175 1 0WCM195_Z8_1 21 32554954 35260482 −0.0139 0.692 2.166 1.065 2 1WCM195_Z8_1 21 35276281 35774409 −1.4363 −0.8117 NA NA NA NA WCM195_Z8_121 35791722 37586402 −0.0291 0.6762 2.2086 0.9872 2 1 WCM195_Z8_1 2137586746 37711087 −1.5961 −0.9872 NA NA NA NA WCM195_Z8_1 21 3771383441741027 −0.0333 0.6719 2.2317 0.9546 2 1 WCM195_Z8_1 21 4206484143557698 −1.5137 −0.8965 1.0091 0.0653 1 0 WCM195_Z8_1 21 4362181148084226 −0.0299 0.6753 2.1974 0.9965 2 1 WCM195_Z8_1 22 1628745951219138 −0.1534 0.5476 1.8963 1.0271 2 1 WCM195_Z8_1 3 239436 1978947260.2548 0.9686 1.9569 1.9569 2 2 WCM195_Z8_1 4 59334 164061482 −0.1420.5595 1.9423 1.0051 2 1 WCM195_Z8_1 4 164066938 186170237 −0.6836−0.0059 1.9407 0.0512 2 0 WCM195_Z8_1 4 186180113 186515084 −0.10850.5941 NA NA NA NA WCM195_Z8_1 4 186528433 187209696 −0.6549 0.0244 NANA NA NA WCM195_Z8_1 4 187348233 190426502 −0.1495 0.5517 NA NA NA NAWCM195_Z8_1 5 140636 7897346 0.1731 0.8846 1.8785 1.814 2 2 WCM195_Z8_15 7900145 10227732 −0.7663 −0.093 NA NA NA NA WCM195_Z8_1 5 1023534039377031 0.2093 0.9218 1.9646 1.8244 2 2 WCM195_Z8_1 5 39377301 40681138−0.7287 −0.0533 NA NA NA NA WCM195_Z8_1 5 40681469 161580375 0.2040.9164 1.8874 1.8874 2 2 WCM195_Z8_1 5 162866353 162945299 −0.63970.0404 NA NA NA NA WCM195_Z8_1 5 166711885 180687769 0.2474 0.961 1.96071.9327 2 2 WCM195_Z8_1 6 203509 16145325 0.2487 0.9623 1.9884 1.9084 2 2WCM195_Z8_1 6 16145435 66115161 −0.1334 0.5684 1.9542 1.0114 2 1WCM195_Z8_1 6 66200549 74530266 −1.5055 −0.8874 1.0519 0.0292 1 0WCM195_Z8_1 6 74533342 81053500 −0.1108 0.5918 1.7863 1.2279 2 1WCM195_Z8_1 6 82204799 89675731 −1.4982 −0.8795 1.0473 0.0398 1 0WCM195_Z8_1 6 89790737 124125396 −0.1376 0.564 1.9346 1.0221 2 1WCM195_Z8_1 6 124604279 127440392 −0.7201 −0.0443 NA NA NA NAWCM195_Z8_1 6 127469973 170893435 −0.1301 0.5718 1.965 1.0077 2 1WCM195_Z8_1 7 193222 84727188 −0.1373 0.5644 1.9473 1.0101 2 1WCM195_Z8_1 7 84751103 93633525 −0.6633 0.0156 2.0031 0.0186 2 0WCM195_Z8_1 7 94024405 110603137 −0.142 0.5595 1.9255 1.0219 2 1WCM195_Z8_1 7 110763015 117880031 0.3966 1.114 NA NA NA NA WCM195_Z8_1 7119914746 124533800 −0.1446 0.5567 1.96 0.9819 2 1 WCM195_Z8_1 7126079195 133261358 0.2752 0.9895 2.01 1.9611 2 2 WCM195_Z8_1 7133261625 151049914 0.5347 1.2553 2.8703 1.9041 3 2 WCM195_Z8_1 7151052937 158937375 −0.1228 0.5793 1.9226 1.0657 2 1 WCM195_Z8_1 8190907 49987715 0.2172 0.93 1.9248 1.8857 2 2 WCM195_Z8_1 8 5044979371646613 −0.6824 −0.0045 1.9467 0.0471 2 0 WCM195_Z8_1 8 72111599146279483 0.2268 0.9398 1.94 1.8966 2 2 WCM195_Z8_1 9 17101 87338160.3001 1.015 2.0438 1.9981 2 2 WCM195_Z8_1 9 12694159 16738401 −0.6929−0.0156 NA NA NA NA WCM195_Z8_1 9 17135137 17579270 0.3023 1.0173 NA NANA NA WCM195_Z8_1 9 17747061 18723029 −0.7256 −0.0501 NA NA NA NAWCM195_Z8_1 9 18753396 19424700 0.1859 0.8978 NA NA NA NA WCM195_Z8_1 919435061 21077820 −0.6688 0.0098 NA NA NA NA WCM195_Z8_1 9 2114107821239884 0.2551 0.9689 NA NA NA NA WCM195_Z8_1 9 21304913 27950658−0.6908 −0.0134 NA NA NA NA WCM195_Z8_1 9 28863629 35313921 0.22970.9428 2.023 1.8216 2 2 WCM195_Z8_1 9 35364549 94712154 0.5474 1.26822.832 1.9853 3 2 WCM195_Z8_1 9 94794652 100919921 0.2398 0.9532 2.87091.0014 3 1 WCM195_Z8_1 9 100961805 139618094 0.5479 1.2688 2.843 1.97633 2 WCM195_Z8_1 9 139618190 141111414 0.2889 1.0036 2.9926 1.0173 3 1WCM195_Z8_1 X 2707688 154509348 0.2178 0.9305 NA NA NA NA WCM198 1 14930249214028 −0.1189 0.0233 1.0201 1.0124 1 1 WCM198 10 225938 135438980−0.1225 0.0163 1.0114 1.0114 1 1 WCM198 11 193097 134605831 −0.1428−0.0229 0.9995 0.969 1 1 WCM198 12 148388 7459291 −0.1344 −0.0066 1.00880.982 1 1 WCM198 12 7459351 27919810 −0.5581 −0.9792 0.9893 0.0252 1 0WCM198 12 27924111 95927187 −0.1461 −0.0291 0.9971 0.9629 1 1 WCM198 1295927650 133810883 0.2223 0.6169 1.9979 1.0693 2 1 WCM198 13 19042044111536114 −0.5838 −1.0529 0.9457 0.0183 1 0 WCM198 13 111545534115089411 −0.074 0.1077 2.1278 0.0272 2 0 WCM198 14 19110394 20181525−0.3163 −0.3804 NA NA NA NA WCM198 14 20215815 21681123 0.4695 0.99481.9929 1.9929 2 2 WCM198 14 21698574 31425358 0.8615 1.5376 3.66082.1456 4 2 WCM198 14 31483953 31647448 0.448 0.9632 NA NA NA NA WCM19814 31674980 107283269 −0.1286 0.0047 2.0068 −4.00E−04  2 0 WCM198 1520083887 102506320 −0.1306  8.00E−04 1.016 0.9852 1 1 WCM198 16 6757035136495 −0.1496 −0.0359 0.9963 0.9545 1 1 WCM198 16 46507933 60393404−0.5599 −0.9845 1.0125 −0.0017 1 0 WCM198 16 61687719 90260461 −0.12840.005 1.0189 0.9881 1 1 WCM198 17 131595 16675378 −0.1722 −0.0804 1.9195−0.0279 2 0 WCM198 17 16676829 20209329 0.4577 0.9774 1.9747 1.9632 2 2WCM198 17 20217316 81187829 0.2143 0.6041 1.9647 1.0754 2 1 WCM198 1847593 15057262 0.6807 1.2943 3.8568 1.0483 4 1 WCM198 18 1525436724722788 0.2092 0.5958 1.9836 1.0391 2 1 WCM198 18 24917001 78005123−0.5782 −1.0367 0.9726 0.0022 1 0 WCM198 19 105021 29699152 0.19060.5658 1.9297 1.0308 2 1 WCM198 19 30017605 59021241 0.3956 0.88531.8472 1.8472 2 2 WCM198 19 59021398 59093696 0.183 0.5534 NA NA NA NAWCM198 2 41680 243052749 −0.1543 −0.0452 0.9691 0.9691 1 1 WCM198 2068337 62934623 0.1509 0.5008 1.9294 0.9006 2 1 WCM198 21 959031439903442 −0.1726 −0.0811 0.9734 0.9173 1 1 WCM198 21 39906086 42848452−0.5645 −0.9975 1.1075 −0.1057 1 0 WCM198 21 42851135 48084198 −0.0840.089 1.0795 1.0478 1 1 WCM198 22 16159046 51223730 −0.1038 0.05181.0366 1.0366 1 1 WCM198 3 239347 148460718 −0.136 −0.0096 0.9934 0.99341 1 WCM198 3 148545681 197896818 0.1593 0.5146 1.8566 1.0006 2 1 WCM1984 53360 13604632 −0.1965 −0.1287 0.9385 0.8907 1 1 WCM198 4 1360496131144294 −0.6118 −1.1363 0.9166 −0.0067 1 0 WCM198 4 36069041 190904468−0.1587 −0.0537 0.9635 0.9635 1 1 WCM198 5 90751 45696101 0.6486 1.24993.7483 1.0082 4 1 WCM198 5 49694853 116052172 −0.5818 −1.0472 0.94820.0196 1 0 WCM198 5 118176549 129100561 0.1376 0.4788 1.6878 1.0994 2 1WCM198 5 129100796 134077219 −0.6088 −1.1272 0.9743 −0.0586 1 0 WCM198 5134079712 139931766 0.1154 0.4417 1.6639 1.0525 2 1 WCM198 5 139936747140864810 −0.096 0.0666 NA NA NA NA WCM198 5 140865096 180687800 0.15060.5003 1.7184 1.1106 2 1 WCM198 6 203475 170892848 0.1879 0.5614 1.91221.0391 2 1 WCM198 7 193189 102114064 −0.1437 −0.0246 1.006 0.9602 1 1WCM198 7 102119351 104707175 −0.5729 −1.0215 1.0334 −0.0482 1 0 WCM198 7104714103 158937046 −0.1293 0.0033 1.0158 0.9888 1 1 WCM198 8 16354942958855 −0.1247 0.012 1.9548 0.062 2 0 WCM198 8 42977330 1462794800.8366 1.5047 3.7138 1.9613 4 2 WCM198 9 14811 334337 0.0558 0.3401 NANA NA NA WCM198 9 334430 16416376 0.457 0.9764 1.9676 1.9676 2 2 WCM1989 16416800 71436975 0.3467 0.8114 1.7951 1.7147 2 2 WCM198 9 71437519127934237 0.4684 0.9932 1.9906 1.9906 2 2 WCM198 9 127951255 1411075190.2265 0.6236 1.9892 1.0923 2 1 WCM198 X 2700216 154509348 −0.1884−0.1124 NA NA NA NA WCM198_Z1_1 1 69590 249212550 −0.2018 0.0379 1.03291.0204 1 1 WCM198_Z1_1 10 225958 135440081 −0.2608 −0.0222 0.9927 0.97671 1 WCM198_Z1_1 11 193112 134856536 −0.2554 −0.0167 1.046 0.931 1 1WCM198_Z1_1 12 148642 7361725 −0.2285 0.0107 1.0167 0.9982 1 1WCM198_Z1_1 12 7362282 27916082 −1.1518 −0.939 1.0305 0.0127 1 0WCM198_Z1_1 12 27916224 33532808 −0.2289 0.0104 1.0483 0.9661 1 1WCM198_Z1_1 12 33538103 38710819 −1.1275 −0.9138 NA NA NA NA WCM198_Z1_112 38712108 96184039 −0.2454 −0.0066 1.0046 0.9863 1 1 WCM198_Z1_1 1296216930 133810896 0.3147 0.5631 1.9867 0.9682 2 1 WCM198_Z1_1 1319600159 111536111 −1.1667 −0.9545 1.0304 0.0016 1 0 WCM198_Z1_1 13111545487 115089411 −0.2876 −0.0496 1.9321 3.00E−04 2 0 WCM198_Z1_1 1419377727 21571367 0.6698 0.9225 1.8954 1.8954 2 2 WCM198_Z1_1 1421584732 31495229 1.2254 1.4831 3.6261 1.9648 4 2 WCM198_Z1_1 1431495393 31762562 0.8159 1.07 NA NA NA NA WCM198_Z1_1 14 31762794107283197 −0.2385  5.00E−04 2.0007 0 2 0 WCM198_Z1_1 15 2017015074748972 −0.2495 −0.0107 1.0716 0.9136 1 1 WCM198_Z1_1 15 7475116875094783 −1.176 −0.9642 NA NA NA NA WCM198_Z1_1 15 75105273 102506282−0.2735 −0.0352 0.9939 0.958 1 1 WCM198_Z1_1 16 67604 34682238 −0.2747−0.0364 0.991 0.9591 1 1 WCM198_Z1_1 16 46509877 60393311 −1.2086−0.9981 1.0051 −0.0037 1 0 WCM198_Z1_1 16 61681688 90233642 −0.2574−0.0188 1.0001 0.9739 1 1 WCM198_Z1_1 17 131595 16594014 −0.2678 −0.02941.95 0.0096 2 0 WCM198_Z1_1 17 16610800 20484011 0.6953 0.9482 1.92951.9295 2 2 WCM198_Z1_1 17 20770002 22023445 −0.4537 −0.2194 0.96710.7508 1 1 WCM198_Z1_1 17 25620983 81083455 0.3061 0.5543 1.9419 0.995 21 WCM198_Z1_1 18 48996 15006107 1.0136 1.2695 3.8137 1.008 4 1WCM198_Z1_1 18 18531342 25543462 0.2969 0.545 2.002 0.9161 2 1WCM198_Z1_1 18 25565081 78005215 −1.1679 −0.9558 1.0333 −0.0022 1 0WCM198_Z1_1 19 281467 24310774 0.2901 0.5381 1.9174 0.9868 2 1WCM198_Z1_1 19 29567134 59083970 0.683 0.9358 1.9129 1.9129 2 2WCM198_Z1_1 2 41620 242946607 −0.2336 0.0055 1.0151 0.9925 1 1WCM198_Z1_1 20 68373 30686877 0.2226 0.4696 1.8794 0.8901 2 1WCM198_Z1_1 20 30689267 62904847 0.0042 0.2477 1.4772 0.8975 1 1WCM198_Z1_1 21 9826230 39818748 −0.2404 −0.0014 1.0224 0.9756 1 1WCM198_Z1_1 21 39822803 42851139 −1.1656 −0.9534 NA NA NA NA WCM198_Z1_121 42852497 48084281 −0.2866 −0.0486 0.9817 0.9521 1 1 WCM198_Z1_1 2216287467 51219138 −0.2553 −0.0166 0.9976 0.9795 1 1 WCM198_Z1_1 3 239347148458977 −0.2438 −0.0049 1.0038 0.9895 1 1 WCM198_Z1_1 3 148459322197894720 0.2708 0.5185 1.8727 0.9923 2 1 WCM198_Z1_1 4 59345 13629026−0.7032 −0.4754 0.9774 0.4611 1 0 WCM198_Z1_1 4 15003701 31144395−1.1946 −0.9835 1.0108 6.00E−04 1 0 WCM198_Z1_1 4 36069805 49052830−0.6145 −0.3843 0.9667 0.5656 1 1 WCM198_Z1_1 4 49063850 190426570−0.1445 0.0964 1.0789 1.0593 1 1 WCM198_Z1_1 5 140526 45695823 0.91531.1704 3.5363 0.9653 4 1 WCM198_Z1_1 5 49695734 115833034 −1.1613−0.9489 1.0344 0.0017 1 0 WCM198_Z1_1 5 115837961 129241266 0.11780.3632 1.575 0.9975 2 1 WCM198_Z1_1 5 129243923 134077023 −1.1583−0.9458 1.0155 0.0228 1 0 WCM198_Z1_1 5 134079721 180687804 0.06020.3047 1.4976 0.9728 1 1 WCM198_Z1_1 6 203699 170893408 0.2863 0.53421.9093 0.987 2 1 WCM198_Z1_1 7 193254 102257116 −0.2724 −0.0341 1.05340.8999 1 1 WCM198_Z1_1 7 102392141 104485841 −1.1137 −0.8995 NA NA NA NAWCM198_Z1_1 7 104681423 158937018 −0.2675 −0.0291 0.993 0.967 1 1WCM198_Z1_1 8 190906 43052876 −0.273 −0.0347 1.9429 0.0095 2 0WCM198_Z1_1 8 43054597 146279423 1.2304 1.4881 3.7149 1.8953 4 2WCM198_Z1_1 9 17101 127996232 0.6781 0.9309 1.9065 1.9065 2 2WCM198_Z1_1 9 127999000 141111414 0.2579 0.5055 1.8559 0.9833 2 1WCM198_Z1_1 X 2700147 154509348 −0.3112 −0.0737 NA NA NA NA WCM199 114907 249213458 0.059 NA NA NA NA NA WCM199 10 225912 135477892 −0.0037NA NA NA NA NA WCM199 11 193112 45935361 0.0727 NA NA NA NA NA WCM199 1145935781 66193482 −0.0318 NA NA NA NA NA WCM199 11 66193938 1346059590.0436 NA NA NA NA NA WCM199 12 148427 133810769 −0.0204 NA NA NA NA NAWCM199 13 19041965 115089411 0.0075 NA NA NA NA NA WCM199 14 19110194107283169 0.029 NA NA NA NA NA WCM199 15 20083875 102514158 0.0064 NA NANA NA NA WCM199 16 64401 90168697 −0.0277 NA NA NA NA NA WCM199 17131595 81052609 0.0044 NA NA NA NA NA WCM199 18 47686 78005206 0.0431 NANA NA NA NA WCM199 19 105021 59093696 −0.04 NA NA NA NA NA WCM199 241670 243037045 −0.0049 NA NA NA NA NA WCM199 20 68337 62934572 0.0548NA NA NA NA NA WCM199 21 9590311 48084201 −0.0023 NA NA NA NA NA WCM19922 16159043 51219090 0.0149 NA NA NA NA NA WCM199 3 239431 1301141410.0209 NA NA NA NA NA WCM199 3 130116470 197659088 0.1088 NA NA NA NA NAWCM199 3 197665463 197896728 −0.0426 NA NA NA NA NA WCM199 4 53345190903980 0.0032 NA NA NA NA NA WCM199 5 90750 180687824 0.049 NA NA NANA NA WCM199 6 203374 170892918 −0.0067 NA NA NA NA NA WCM199 7 195702158937046 0.0264 NA NA NA NA NA WCM199 8 163438 146279481 0.025 NA NA NANA NA WCM199 9 14887 141107536 0.0155 NA NA NA NA NA WCM199 X 2700166154493394 −0.0569 NA NA NA NA NA WCM199_Z3_1 1 721415 29189597 −0.3280.0265 2.0315 0.0056 2 0 WCM199_Z3_1 1 29314018 45671942 0.8136 1.31862.8936 2.0947 3 2 WCM199_Z3_1 1 45792829 46531740 −0.2834 0.0799 NA NANA NA WCM199_Z3_1 1 46532734 47280884 0.8377 1.3446 NA NA NA NAWCM199_Z3_1 1 47282840 48267161 −0.3505 −6.00E−04 NA NA NA NAWCM199_Z3_1 1 48459721 65349137 0.7819 1.2842 2.8447 2.0262 3 2WCM199_Z3_1 1 65523519 113256142 0.086 0.5111 1.8522 0.9981 2 1WCM199_Z3_1 1 113264930 192335065 0.775 1.2767 2.9431 1.9026 3 2WCM199_Z3_1 1 192545005 249212495 0.1142 0.5433 1.9343 0.9803 2 1WCM199_Z3_1 10 243934 128335169 −0.377 −0.0326 0.9883 0.967 1 1WCM199_Z3_1 10 128358921 129350888 −1.1574 −1.048 NA NA NA NAWCM199_Z3_1 10 129534603 135440117 −0.2961 0.0648 1.1597 0.9321 1 1WCM199_Z3_1 11 193112 17436875 0.131 0.5624 1.9846 0.9689 2 1WCM199_Z3_1 11 17438506 17498219 −1.209 −1.1221 NA NA NA NA WCM199_Z3_111 17515924 78602285 0.128 0.559 1.9531 0.9933 2 1 WCM199_Z3_1 1178614351 83641490 −0.4375 −0.1061 NA NA NA NA WCM199_Z3_1 11 83674042134856523 0.0954 0.5219 1.9198 0.9518 2 1 WCM199_Z3_1 12 148675 1042182−0.3521 −0.0026 NA NA NA NA WCM199_Z3_1 12 1137182 15067706 −1.1087−0.9792 1.0214 −0.0069 1 0 WCM199_Z3_1 12 15068467 132467012 −0.3731−0.0279 1.0212 0.9406 1 1 WCM199_Z3_1 12 132471230 133810926 −1.083−0.9433 1.047 −0.0069 1 0 WCM199_Z3_1 13 19600371 25077801 0.1173 0.54691.7008 1.221 2 1 WCM199_Z3_1 13 25254891 26104202 −0.3819 −0.0385 NA NANA NA WCM199_Z3_1 13 26104750 46288145 0.0695 0.4922 1.7676 1.0457 2 1WCM199_Z3_1 13 46288408 48941658 −0.4105 −0.0732 NA NA NA NA WCM199_Z3_113 48942680 49109832 −2.5224 −4.0008 NA NA NA NA WCM199_Z3_1 13 4928112150007525 −1.0979 −0.964 NA NA NA NA WCM199_Z3_1 13 50018165 99112680−0.2986 0.0617 1.0724 1.015 1 1 WCM199_Z3_1 13 99114053 115089411 0.1840.6227 1.9985 1.0809 2 1 WCM199_Z3_1 14 19377726 38183916 0.5339 1.01332.0186 2.0186 2 2 WCM199_Z3_1 14 38194107 107283213 0.1443 0.5776 1.98790.9968 2 1 WCM199_Z3_1 15 20170150 38990605 −0.4074 −0.0694 1.07920.8268 1 1 WCM199_Z3_1 15 39544512 40576723 −1.1531 −1.0419 NA NA NA NAWCM199_Z3_1 15 40581093 102517666 −0.3785 −0.0344 0.9906 0.9623 1 1WCM199_Z3_1 16 66943 2200038 −0.989 −0.8138 1.1128 0.025 1 0 WCM199_Z3_116 2201144 68772307 −0.3152 0.0418 1.0442 1.0146 1 1 WCM199_Z3_1 1668835730 90161609 −1.0483 −0.8952 1.0649 0.0105 1 0 WCM199_Z3_1 17131595 5487276 0.5462 1.0268 2.0666 2.0083 2 2 WCM199_Z3_1 17 59841628812440 −0.2997 0.0604 2.067 0.0185 2 0 WCM199_Z3_1 17 8814786 125695120.4846 0.9589 1.9718 1.9159 2 2 WCM199_Z3_1 17 12608461 20931877 −0.3450.0061 2.015 −0.0065 2 0 WCM199_Z3_1 17 20946104 21454632 0.0741 0.49751.491 1.3325 1 1 WCM199_Z3_1 17 21730846 45895647 −0.3315 0.0222 2.01130.0197 2 0 WCM199_Z3_1 17 45895908 81083455 0.1439 0.5771 2.0314 0.95232 1 WCM199_Z3_1 18 48234 52608292 0.4763 0.9497 1.94 1.9229 2 2WCM199_Z3_1 18 52609955 57569959 −0.3668 −0.0202 1.9781 −0.0059 2 0WCM199_Z3_1 18 58038807 59828538 0.4107 0.877 NA NA NA NA WCM199_Z3_1 1859854838 78005210 −0.3955 −0.055 1.9035 0.0217 2 0 WCM199_Z3_1 19 28150859083929 −0.3437 0.0075 1.119 0.8915 1 1 WCM199_Z3_1 2 41623 242946604−0.3293 0.0249 1.0394 0.9954 1 1 WCM199_Z3_1 20 68351 37005528 0.14560.5791 1.9151 1.0726 2 1 WCM199_Z3_1 20 37053870 39742726 −0.3441 0.0071NA NA NA NA WCM199_Z3_1 20 39744078 62904863 0.4794 0.9532 1.9361 1.93612 2 WCM199_Z3_1 21 9826230 39817483 −0.338 0.0144 1.1498 0.8703 1 1WCM199_Z3_1 21 39818741 42866297 −1.0521 −0.9003 1.0379 0.0336 1 0WCM199_Z3_1 21 42870050 48084211 −0.2747 0.0902 1.0823 1.0468 1 1WCM199_Z3_1 22 16287437 26348385 −0.3323 0.0213 1.0381 0.9917 1 1WCM199_Z3_1 22 26351317 29195959 −1.217 −1.1336 0.8891 0.0224 1 0WCM199_Z3_1 22 29279991 29976094 −0.3175 0.0391 1.1051 0.9498 1 1WCM199_Z3_1 22 29977037 32924933 −1.107 −0.9768 1.0178 −0.0016 1 0WCM199_Z3_1 22 32929841 51219138 −0.3448 0.0063 1.0261 0.9826 1 1WCM199_Z3_1 3 239443 9920138 −0.3282 0.0262 1.0587 0.978 1 1 WCM199_Z3_13 9934740 10191495 −1.0508 −0.8986 NA NA NA NA WCM199_Z3_1 3 1020670126751779 −0.3261 0.0287 1.0434 0.9968 1 1 WCM199_Z3_1 3 2715276735835317 −1.0088 −0.8408 1.0933 0.0234 1 0 WCM199_Z3_1 3 3642213547555052 0.1939 0.6339 1.9136 1.1899 2 1 WCM199_Z3_1 3 47604152 53925815−0.3025 0.0571 2.105 −0.0243 2 0 WCM199_Z3_1 3 54157575 70014365 0.51440.9917 2.0039 1.9732 2 2 WCM199_Z3_1 3 71007463 109321699 0.0519 0.4721.8901 0.884 2 1 WCM199_Z3_1 3 110611201 119962908 −1.1064 −0.97591.0177 −8.00E−04  1 0 WCM199_Z3_1 3 120050075 132440575 0.1458 0.57932.0446 0.9437 2 1 WCM199_Z3_1 3 132440864 197894719 1.0075 1.5273 3.94141.8235 4 2 WCM199_Z3_1 4 59448 190426570 −0.3827 −0.0395 1.0495 0.8964 11 WCM199_Z3_1 5 140636 37247740 0.437 0.9062 1.9095 1.8388 2 2WCM199_Z3_1 5 37292124 39394368 −0.4066 −0.0685 NA NA NA NA WCM199_Z3_15 40681118 180687776 0.462 0.9339 1.9252 1.8956 2 2 WCM199_Z3_1 6 203510108227912 −0.3644 −0.0174 0.9988 0.9773 1 1 WCM199_Z3_1 6 108232558109690101 −1.0962 −0.9617 NA NA NA NA WCM199_Z3_1 6 109691656 160241520−0.3851 −0.0423 0.9875 0.9546 1 1 WCM199_Z3_1 6 160328065 160872045−1.0856 −0.9469 NA NA NA NA WCM199_Z3_1 6 160908460 170893411 −0.3569−0.0083 1.0099 0.9787 1 1 WCM199_Z3_1 7 193436 100608823 0.0846 0.50951.8893 0.9578 2 1 WCM199_Z3_1 7 100609566 134962033 −0.411 −0.07381.9342 −0.0339 2 0 WCM199_Z3_1 7 135047620 158937416 0.4769 0.95041.9345 1.9303 2 2 WCM199_Z3_1 8 190906 146279508 0.3432 0.8018 2.53220.9543 3 1 WCM199_Z3_1 9 17086 3469160 −0.4179 −0.0823 0.9756 0.9135 1 1WCM199_Z3_1 9 3828281 7165343 −1.1072 −0.9771 1.0098 0.0062 1 0WCM199_Z3_1 9 7170006 22451906 0.1137 0.5427 1.9851 0.9284 2 1WCM199_Z3_1 9 23692600 28888941 −1.1075 −0.9775 NA NA NA NA WCM199_Z3_19 32384732 141111414 −0.3448 0.0063 1.0177 0.9911 1 1 WCM199_Z3_1 X2700139 51644748 0.2692 0.7188 NA NA NA NA WCM199_Z3_1 X 52677392154509348 0.5231 1.0014 NA NA NA NA WCM1_T 1 809178 898507 0.0422 NA NANA NA NA WCM1_T 1 898703 55224766 −0.0485 NA NA NA NA NA WCM1_T 155251822 145209427 0.0112 NA NA NA NA NA WCM1_T 1 145295450 152060431−0.0956 NA NA NA NA NA WCM1_T 1 152060670 153391648 0.1007 NA NA NA NANA WCM1_T 1 153409671 156764528 −0.0628 NA NA NA NA NA WCM1_T 1156767081 249212465 0.0298 NA NA NA NA NA WCM1_T 10 226039 69565336−0.03 NA NA NA NA NA WCM1_T 10 69565561 70741319 −0.2088 NA NA NA NA NAWCM1_T 10 70742279 135440041 −0.0198 NA NA NA NA NA WCM1_T 11 19315446455047 0.0459 NA NA NA NA NA WCM1_T 11 46456582 48134313 −0.0863 NA NANA NA NA WCM1_T 11 48134527 134257488 0.0189 NA NA NA NA NA WCM1_T 12247582 52470799 −0.0068 NA NA NA NA NA WCM1_T 12 52565153 53215782 0.183NA NA NA NA NA WCM1_T 12 53216113 56233259 −0.0257 NA NA NA NA NA WCM1_T12 56233522 57181004 −0.1007 NA NA NA NA NA WCM1_T 12 57317623 1184547210.0077 NA NA NA NA NA WCM1_T 12 118456884 133779230 −0.1263 NA NA NA NANA WCM1_T 13 19705463 115089411 0.0213 NA NA NA NA NA WCM1_T 14 1955369522294221 −0.0208 NA NA NA NA NA WCM1_T 14 22309448 23016560 0.5751 NA NANA NA NA WCM1_T 14 23016747 30066976 0.053 NA NA NA NA NA WCM1_T 1430068194 104474806 −0.0118 NA NA NA NA NA WCM1_T 14 104481083 1072831560.0604 NA NA NA NA NA WCM1_T 15 20170048 102359217 −0.0357 NA NA NA NANA WCM1_T 16 97541 90162322 −0.0449 NA NA NA NA NA WCM1_T 17 13159516340164 −0.1042 NA NA NA NA NA WCM1_T 17 16342582 80401890 −0.0287 NANA NA NA NA WCM1_T 17 80402296 81052325 −0.0743 NA NA NA NA NA WCM1_T 1847756 78005206 0.0118 NA NA NA NA NA WCM1_T 19 156724 14063267 −0.1231NA NA NA NA NA WCM1_T 19 14065176 16060772 0.0485 NA NA NA NA NA WCM1_T19 16178540 30314701 −0.1454 NA NA NA NA NA WCM1_T 19 30433534 36297389−0.0035 NA NA NA NA NA WCM1_T 19 36297760 49794028 −0.1336 NA NA NA NANA WCM1_T 19 49796617 59082605 −0.0384 NA NA NA NA NA WCM1_T 2 4159564331975 −0.0361 NA NA NA NA NA WCM1_T 2 64335349 135476319 0.0214 NA NANA NA NA WCM1_T 2 135476550 136872444 −0.0645 NA NA NA NA NA WCM1_T 2136872912 179399659 0.0664 NA NA NA NA NA WCM1_T 2 179400105 1796692810.1688 NA NA NA NA NA WCM1_T 2 179701746 196771309 0.0713 NA NA NA NA NAWCM1_T 2 196771736 242815461 0.0219 NA NA NA NA NA WCM1_T 20 6842762904819 −0.006 NA NA NA NA NA WCM1_T 21 9590301 48084202 0.0023 NA NANA NA NA WCM1_T 22 16255843 51216406 −0.0194 NA NA NA NA NA WCM1_T 3361455 195622236 0.0367 NA NA NA NA NA WCM1_T 3 195778899 197847360−0.0967 NA NA NA NA NA WCM1_T 4 53400 140375549 −0.0339 NA NA NA NA NAWCM1_T 4 140393856 187630541 0.0449 NA NA NA NA NA WCM1_T 4 187630910190947560 −0.2104 NA NA NA NA NA WCM1_T 5 140657 180687808 0.0286 NA NANA NA NA WCM1_T 6 311934 170893507 −0.0015 NA NA NA NA NA WCM1_T 7193546 6859561 −0.053 NA NA NA NA NA WCM1_T 7 7118608 38292948 0.0533 NANA NA NA NA WCM1_T 7 38295985 38388945 0.7638 NA NA NA NA NA WCM1_T 738389276 55750390 0.0376 NA NA NA NA NA WCM1_T 7 55752915 77648591−0.1074 NA NA NA NA NA WCM1_T 7 77649052 97780714 0.0457 NA NA NA NA NAWCM1_T 7 97784061 103123404 −0.1042 NA NA NA NA NA WCM1_T 7 103124075142008695 0.0078 NA NA NA NA NA WCM1_T 7 142008902 142612658 0.2814 NANA NA NA NA WCM1_T 7 142622780 158937400 0.0317 NA NA NA NA NA WCM1_T 8190908 48749976 −0.0549 NA NA NA NA NA WCM1_T 8 48751747 1458064910.1368 NA NA NA NA NA WCM1_T 8 145830968 146279396 0.0237 NA NA NA NA NAWCM1_T 9 117703 127302393 0.0196 NA NA NA NA NA WCM1_T 9 127306158135278208 −0.0468 NA NA NA NA NA WCM1_T 9 135285650 141071165 0.0304 NANA NA NA NA WCM1_T X 2700145 154509348 0.0292 NA NA NA NA NA WCM2 117468 249213964 −0.0149 −0.0673 0.9544 0.9544 1 1 WCM2 10 225995135439008 0.008 0.1202 1.0869 1.0869 1 1 WCM2 11 193096 134605954−0.0334 −0.2365 0.8488 0.8488 1 1 WCM2 12 148637 133810703 0.0138 0.16511.1212 1.1212 1 1 WCM2 13 19041994 115089411 0.0243 0.242 1.1826 1.18261 1 WCM2 14 19110239 107283270 0.0288 0.2741 1.2093 1.2093 1 1 WCM2 1520083885 102506252 0.0515 0.4277 1.3451 1.3451 1 1 WCM2 16 66881 304529−0.1161 −1.3482 NA NA NA NA WCM2 16 304633 28963480 0.0462 0.3926 1.31271.3127 1 1 WCM2 16 28967440 90168680 −0.1059 −1.1597 0.4476 0.4476 0 0WCM2 17 131595 6900133 −0.0746 −0.6934 0.6184 0.6184 1 1 WCM2 17 690187917394791 −0.1948 NA −0.0172 −0.0172 0 0 WCM2 17 17397915 81187845−0.0347 −0.2486 0.8417 0.8417 1 1 WCM2 18 47790 78005274 −0.1016 −1.08650.4709 0.4709 0 0 WCM2 19 105050 59093645 −0.1026 −1.1022 0.4658 0.46580 0 WCM2 2 41474 243037003 −0.0011 0.0484 1.0341 1.0341 1 1 WCM2 2068373 62959246 0.051 0.4241 1.3417 1.3417 1 1 WCM2 21 9590393 48084163−0.0645 −0.5678 0.6747 0.6747 1 1 WCM2 22 16159016 51219090 0.03290.3027 1.2335 1.2335 1 1 WCM2 3 239451 89448418 −0.0241 −0.1496 0.90150.9015 1 1 WCM2 3 89456555 196050697 0.0462 0.3932 1.3133 1.3133 1 1WCM2 3 196050725 197896700 −0.0424 −0.326 0.7978 0.7978 1 1 WCM2 4 53396190878479 −0.0297 −0.2008 0.8701 0.8701 1 1 WCM2 5 90647 52356692 0.10680.7521 1.6843 1.6843 2 2 WCM2 5 52356935 145859690 −0.047 −0.3735 0.77190.7719 1 1 WCM2 5 145862179 180687828 0.0626 0.4974 1.4117 1.4117 1 1WCM2 6 203588 170892848 −0.0221 −0.1311 0.9131 0.9131 1 1 WCM2 7 193245158937018 0.0865 0.6398 1.5581 1.5581 2 2 WCM2 8 163474 57125511 −0.0527−0.4336 0.7404 0.7404 1 1 WCM2 8 57127251 125113312 0.1411 0.9265 1.90071.9007 2 2 WCM2 8 125113606 146279489 −0.0677 −0.6068 0.6567 0.6567 1 1WCM2 9 14852 94895143 −0.0716 −0.6556 0.6348 0.6348 1 1 WCM2 9 9489635194899732 −1.3712 NA NA NA NA NA WCM2 9 94900462 141071668 −0.0289−0.1932 0.8747 0.8747 1 1 WCM2 X 2700089 63005022 0.059 0.475 NA NA NANA WCM2 X 63406189 66942624 0.9706 3.1821 NA NA NA NA WCM2 X 6726834067742721 0.1623 1.0271 NA NA NA NA WCM2 X 67751827 154493598 −0.1414−1.9501 NA NA NA NA WCM201 1 14930 249214018 0.0265 0.1054 1.0758 1.07581 1 WCM201 10 225981 135438983 0.0241 0.0927 1.0663 1.0663 1 1 WCM201 11193096 62327458 0.0356 0.1521 1.1565 1.0659 1 1 WCM201 11 6232779366055525 −0.1525 −1.257 0.4831 0.3538 0 0 WCM201 11 66061754 1346058270.0317 0.1322 1.096 1.096 1 1 WCM201 12 148452 133810842 −0.002 −0.05080.9654 0.9654 1 1 WCM201 13 19042044 115089411 0.0191 0.066 1.04681.0468 1 1 WCM201 14 19110203 107283269  3.00E−04 −0.0374 0.9744 0.97441 1 WCM201 15 20083857 102515250 0.0275 0.1102 1.0794 1.0794 1 1 WCM20116 64396 28975045 −0.0098 −0.096 0.9356 0.9356 1 1 WCM201 16 2898644231213839 −0.2184 −2.348 0.3912 0.0016 0 0 WCM201 16 31228239 90260461−0.0108 −0.1019 0.9318 0.9318 1 1 WCM201 17 131595 81187931 −0.0153−0.1288 0.9146 0.9146 1 1 WCM201 18 47801 78005160 0.0294 0.1203 1.0871.087 1 1 WCM201 19 104937 59093645 −0.0625 −0.4371 0.7386 0.7386 1 1WCM201 2 41680 243052762 0.0174 0.0571 1.0403 1.0403 1 1 WCM201 20 6835162934623 0.0242 0.0932 1.0667 1.0667 1 1 WCM201 21 9590369 480841960.0019 −0.0288 0.9802 0.9802 1 1 WCM201 22 16159079 51223730 0.02090.0756 1.0538 1.0538 1 1 WCM201 3 239436 197896801 0.0229 0.086 1.06151.0615 1 1 WCM201 4 53375 190878479 0.0257 0.1009 1.0724 1.0724 1 1WCM201 5 90576 180687854 0.0187 0.064 1.0454 1.0454 1 1 WCM201 6 203545170892854 0.0128 0.0317 1.0222 1.0222 1 1 WCM201 7 193189 1589370720.0232 0.088 1.0629 1.0629 1 1 WCM201 8 163438 146279434 0.02 0.0711.0504 1.0504 1 1 WCM201 9 14856 141107533 0.0214 0.078 1.0555 1.0555 11 WCM201 X 2700108 154493576 −0.0995 −0.7261 NA NA NA NA WCM201_Z1_1 169603 110655683 0.0397 0.9464 1.9494 1.9046 2 2 WCM201_Z1_1 1 110709771116519280 −0.6277 0.0071 2.0378 −0.028 2 0 WCM201_Z1_1 1 116534852161683155 0.1189 1.0479 2.1174 2.0175 2 2 WCM201_Z1_1 1 161692462179851903 −0.0437 0.8376 1.8482 1.726 2 2 WCM201_Z1_1 1 179852118193202135 0.1926 1.141 2.2689 2.1416 2 2 WCM201_Z1_1 1 193205390247875961 −0.0832 0.7855 1.9249 1.5225 2 2 WCM201_Z1_1 1 247886494249212557 0.0673 0.9819 2.4115 1.5386 2 2 WCM201_Z1_1 10 225952 27702540−0.1195 0.7372 1.7405 1.5933 2 2 WCM201_Z1_1 10 27702725 44052903 0.09571.0183 2.0592 1.9919 2 2 WCM201_Z1_1 10 44052986 63525749 0.2797 1.24952.7127 2.0424 3 2 WCM201_Z1_1 10 63662089 81113483 −0.1994 0.6292 1.89681.1966 2 1 WCM201_Z1_1 10 81146052 116201540 −0.6282 0.0063 1.053 0.95581 1 WCM201_Z1_1 10 116203815 135440117 −0.2472 0.5636 1.9371 1.0189 2 1WCM201_Z1_1 11 193106 134856626 −0.0047 0.8887 1.8684 1.8346 2 2WCM201_Z1_1 12 148811 7475108 −0.2755 0.5244 1.9125 0.9641 2 1WCM201_Z1_1 12 7476073 8673804 0.5377 1.5623 NA NA NA NA WCM201_Z1_1 128687326 12044495 −0.6153 0.0264 1.0896 0.9474 1 1 WCM201_Z1_1 1212232265 12673911 0.4248 1.4269 NA NA NA NA WCM201_Z1_1 12 1276511723757357 −0.5153 0.1789 1.1896 1.0744 1 1 WCM201_Z1_1 12 2379381832520605 0.1849 1.1313 2.6972 1.684 3 2 WCM201_Z1_1 12 32530498 54447966−0.0899 0.7765 1.7631 1.6629 2 2 WCM201_Z1_1 12 54448661 55615327 0.48981.5051 NA NA NA NA WCM201_Z1_1 12 55615403 56417527 −0.0935 0.7717 NA NANA NA WCM201_Z1_1 12 56418797 77449736 0.2008 1.1512 2.2683 2.1737 2 2WCM201_Z1_1 12 77458341 82746972 1.1559 2.2732 7.3596 2.3084 7 2WCM201_Z1_1 12 82750772 102444064 0.0828 1.0018 2.1384 1.8665 2 2WCM201_Z1_1 12 102455047 107914392 −0.2369 0.5779 2.064 0.9213 2 1WCM201_Z1_1 12 107937768 113269582 −0.5837 0.0752 1.0972 1.0099 1 1WCM201_Z1_1 12 113275610 133810892 −0.0114 0.8799 2.8254 0.8551 3 1WCM201_Z1_1 13 19600515 115089411 −0.2886 0.5061 1.8366 1.0039 2 1WCM201_Z1_1 14 19377716 107283026 −0.0262 0.8606 1.8372 1.7944 2 2WCM201_Z1_1 15 20170150 102514186 −0.16 0.6828 1.7309 1.4795 2 1WCM201_Z1_1 16 67604 34267311 0.0145 0.9136 1.9009 1.8667 2 2WCM201_Z1_1 16 34274554 68293320 −0.0795 0.7903 1.812 1.647 2 2WCM201_Z1_1 16 68308731 68397442 −0.0013 0.8931 NA NA NA NA WCM201_Z1_116 68397767 68598635 −0.4374 0.294 NA NA NA NA WCM201_Z1_1 16 6867929172188271 −0.3706 0.3904 1.4044 1.2171 1 1 WCM201_Z1_1 16 7219834590233626 −0.5852 0.0728 1.4505 0.6531 1 1 WCM201_Z1_1 17 131595 17171260−0.659 −0.042 1.9361 0.0065 2 0 WCM201_Z1_1 17 17174286 81083567 0.00690.9038 1.8953 1.8467 2 2 WCM201_Z1_1 18 48203 28898294 −0.0124 0.87871.9204 1.7571 2 2 WCM201_Z1_1 18 28906543 40500703 −0.2159 0.6067 2.00861.0369 2 1 WCM201_Z1_1 18 40503597 53723814 0.0576 0.9694 1.9907 1.92522 2 WCM201_Z1_1 18 54278293 56024461 −0.5871 0.0699 NA NA NA NAWCM201_Z1_1 18 56033398 78005197 −0.0823 0.7867 1.8303 1.6199 2 2WCM201_Z1_1 19 281483 59083953 −0.0071 0.8856 1.8644 1.8306 2 2WCM201_Z1_1 2 41623 3826444 −0.1286 0.725 1.7482 1.5576 2 2 WCM201_Z1_12 4135981 9143675 −0.5537 0.121 NA NA NA NA WCM201_Z1_1 2 941948112880905 0.0315 0.9357 1.987 1.8385 2 2 WCM201_Z1_1 2 14774334 20251253−0.6531 −0.0327 NA NA NA NA WCM201_Z1_1 2 20402033 61597484 0.01140.9097 1.9128 1.8445 2 2 WCM201_Z1_1 2 61605543 74458429 −0.6128 0.03041.9984 0.0441 2 0 WCM201_Z1_1 2 74459683 147596973 0.0121 0.9106 1.92621.8334 2 2 WCM201_Z1_1 2 148653948 152460230 −0.6968 −0.1022 1.82510.0381 2 0 WCM201_Z1_1 2 152466498 170558145 0.015 0.9143 1.9287 1.84062 2 WCM201_Z1_1 2 170591627 171822576 −0.669 −0.0578 NA NA NA NAWCM201_Z1_1 2 171850329 242946616 0.0115 0.9098 1.913 1.8447 2 2WCM201_Z1_1 20 68406 62904866 −0.0296 0.8562 2.0214 1.5991 2 2WCM201_Z1_1 21 9826205 48084277 −0.0112 0.8802 1.8743 1.807 2 2WCM201_Z1_1 22 17063485 51215138 −0.1704 0.6686 1.6132 1.5658 2 2WCM201_Z1_1 3 239405 111439610 0.0526 0.9629 1.9493 1.9493 2 2WCM201_Z1_1 3 111451475 134670524 −0.1543 0.6905 2.3581 0.8695 2 1WCM201_Z1_1 3 134670759 197894720 0.1972 1.1467 2.2641 2.1641 2 2WCM201_Z1_1 4 59327 190426459 −0.0769 0.7938 1.752 1.7152 2 2WCM201_Z1_1 5 140632 52216256 0.0213 0.9225 1.9568 1.8339 2 2WCM201_Z1_1 5 52218705 79617319 −0.2055 0.6209 1.9053 1.1702 2 1WCM201_Z1_1 5 79654971 180687776 0.0399 0.9466 1.9423 1.9124 2 2WCM201_Z1_1 6 203515 350829 −0.3525 0.4162 NA NA NA NA WCM201_Z1_1 6367481 16328258 −0.3344 0.4419 1.5505 1.1663 2 1 WCM201_Z1_1 6 16328394170892637 −0.0499 0.8295 1.8004 1.7536 2 2 WCM201_Z1_1 7 193451158937135 0.0707 0.9862 1.9962 1.9657 2 2 WCM201_Z1_1 8 190907 41399565−0.7811 −0.2398 1.6573 0.0365 2 0 WCM201_Z1_1 8 41456684 1462795450.1003 1.0241 2.0596 2.0077 2 2 WCM201_Z1_1 9 17075 37955919 −0.21290.6108 1.9011 1.153 2 1 WCM201_Z1_1 9 37974678 105767903 0.0162 0.91591.9308 1.8426 2 2 WCM201_Z1_1 9 106857726 141111414 0.2791 1.2487 2.871.8826 3 2 WCM201_Z1_1 X 2707687 10427687 −0.1191 0.7377 NA NA NA NAWCM201_Z1_1 X 10437702 11139089 0.7532 1.8155 NA NA NA NA WCM201_Z1_1 X11139926 27839452 0.2933 1.2662 NA NA NA NA WCM201_Z1_1 X 2783970857936469 0.5808 1.6134 NA NA NA NA WCM201_Z1_1 X 62898360 73095467 0.0740.9904 NA NA NA NA WCM201_Z1_1 X 73405763 107867540 −0.1761 0.6609 NA NANA NA WCM201_Z1_1 X 107869013 154509348 0.1844 1.1307 NA NA NA NA WCM2071 14930 3662308 −0.2358 0.412 1.9145 0.7465 2 1 WCM207 1 3662677 6029377−0.1821 0.4825 1.7441 1.0503 2 1 WCM207 1 6038450 79474631 0.3189 1.10793.1785 1.1321 3 1 WCM207 1 81967629 146639526 −0.0836 0.61 1.9485 1.1042 1 WCM207 1 146643580 149872078 −0.2276 0.4228 2.4887 0.1924 2 0 WCM2071 149875427 213349637 −0.0212 0.6895 3.1232 0.1022 3 0 WCM207 1213403861 249214018 −0.4797 0.0799 2.0374 0.0765 2 0 WCM207 10 225979135439049 −0.4874 0.069 2.039 0.059 2 0 WCM207 11 193096 1346059590.2985 1.0834 2.119 2.119 2 2 WCM207 12 148430 9849055 −0.2947 0.33361.2788 1.2416 1 1 WCM207 12 9875402 24737345 −1.0977 −0.8907 1.01850.0602 1 0 WCM207 12 24968390 133810855 −0.3519 0.2564 1.1945 1.1945 1 1WCM207 13 19042165 35739216 0.1898 0.9517 1.9341 1.9341 2 2 WCM207 1335743083 48667721 −0.5361 0 1.9742 0.0257 2 0 WCM207 13 4866922349027319 −2.4741 NA NA NA NA NA WCM207 13 49030283 115089411 −0.5498−0.0196 1.9204 0.0526 2 0 WCM207 14 19110174 107283263 0.2402 1.0132.018 2.018 2 2 WCM207 15 20083857 102506258 −0.4698 0.0937 1.06711.0671 1 1 WCM207 16 64396 21812102 0.3401 1.1333 2.1936 2.1936 2 2WCM207 16 21813932 22337593 −0.3326 0.2826 NA NA NA NA WCM207 1622339794 29000870 0.3081 1.095 2.1361 2.1361 2 2 WCM207 16 2900120529974704 −0.4355 0.1416 NA NA NA NA WCM207 16 29974864 52689967 0.19720.9606 2.0174 1.8749 2 2 WCM207 16 53190128 90260461 −0.4841 0.07362.0298 0.0749 2 0 WCM207 17 131595 18220476 −0.5182 0.0255 2.0057 0.02992 0 WCM207 17 18220859 40004450 0.2442 1.0179 2.025 2.025 2 2 WCM207 1740023368 43893780 −0.5045 0.0449 2.023 0.0401 2 0 WCM207 17 4403975781187891 0.2536 1.0292 2.0409 2.0409 2 2 WCM207 18 47779 13681817 0.22470.9942 1.992 1.992 2 2 WCM207 18 13681994 15325957 −0.5145 0.0308 1.83220.2109 2 0 WCM207 18 18529837 31432784 0.2437 1.0173 2.0241 2.0241 2 2WCM207 18 31433029 78005189 −0.4933 0.0607 2.0466 0.0394 2 0 WCM207 19105080 1013287 0.1914 0.9536 1.9603 1.913 2 2 WCM207 19 1014398 3122138−0.529 0.0101 2.0019 0.0122 2 0 WCM207 19 3136508 16977361 0.2471 1.02132.0298 2.0298 2 2 WCM207 19 16980397 17438011 −0.5049 0.0443 1.99170.0707 2 0 WCM207 19 17438525 39669779 0.2165 0.9843 1.9783 1.9783 2 2WCM207 19 39688815 44174180 −0.4723 0.0903 2.1157 0.0134 2 0 WCM207 1944222843 59093645 0.2348 1.0065 2.009 2.009 2 2 WCM207 2 41602 71432813−0.4946 0.0589 1.0417 1.0417 1 1 WCM207 2 71432918 73118500 −1.0735−0.8477 1.0754 0.036 1 0 WCM207 2 73118674 73497978 −0.4655 0.09981.1121 1.0311 1 1 WCM207 2 73513335 74690512 −1.1123 −0.917 1.00390.0553 1 0 WCM207 2 74691841 74734906 −0.4859 0.0711 NA NA NA NA WCM2072 74741940 85894308 −0.2174 0.4363 1.6204 1.0859 2 1 WCM207 2 8589494686385668 −0.9763 −0.6797 1.2108 0.0379 1 0 WCM207 2 86386755 243037004−0.1823 0.4823 1.6817 1.1122 2 1 WCM207 20 68363 62934592 0.248 1.02252.0314 2.0314 2 2 WCM207 21 9590334 48084202 0.2166 0.9844 1.9784 1.97842 2 WCM207 22 16159060 51219138 −0.4608 0.1063 2.0849 0.0681 2 0 WCM2073 239459 45160011 0.1914 0.9536 1.9367 1.9367 2 2 WCM207 3 4526620446414615 −0.4905 0.0646 2.1206 −0.029 2 0 WCM207 3 46415115 473716440.2797 1.0608 2.0861 2.0861 2 2 WCM207 3 47374842 49004662 −0.46270.1037 NA NA NA NA WCM207 3 49006004 195754093 0.2532 1.0288 2.04032.0403 2 2 WCM207 3 195777375 196310987 −0.356 0.2509 2.407 −0.0272 2 0WCM207 3 196311203 197896720 0.2529 1.0284 2.0398 2.0398 2 2 WCM207 453396 1135648 −0.5112 0.0354 1.9201 0.1295 2 0 WCM207 4 1147513 74616860.2119 0.9786 1.9706 1.9706 2 2 WCM207 4 7533331 26491867 −0.5132 0.03252.0039 0.0417 2 0 WCM207 4 26585787 52961030 0.2479 1.0223 2.0312 2.03122 2 WCM207 4 53304891 69484456 −0.4956 0.0574 1.9911 0.09 2 0 WCM207 469693136 87610220 0.248 1.0225 2.0314 2.0314 2 2 WCM207 4 87614787104101509 −0.4982 0.0538 2.0661 0.0099 2 0 WCM207 4 104101650 1460929630.2021 0.9667 1.9543 1.9543 2 2 WCM207 4 146095879 190878479 −0.50250.0477 1.9987 0.0686 2 0 WCM207 5 90751 32101263 0.1318 0.8805 1.84111.8411 2 2 WCM207 5 32108141 32791867 −0.5412 −0.0074 1.9514 0.0383 2 0WCM207 5 32888214 180687804 0.2236 0.9928 1.9901 1.9901 2 2 WCM207 6203424 34883506 0.5163 1.3415 2.9964 2.072 3 2 WCM207 6 3493499436046518 −0.4001 0.1905 2.3153 −0.033 2 0 WCM207 6 36063789 362983370.2142 0.9814 NA NA NA NA WCM207 6 36322317 36652242 −0.4438 0.1301 NANA NA NA WCM207 6 36653610 45922904 0.2568 1.0331 2.0464 2.0464 2 2WCM207 6 46028186 170892883 −0.0757 0.6201 1.9341 1.14 2 1 WCM207 7193222 158937022 0.1721 0.93 1.9053 1.9053 2 2 WCM207 8 163474 39203434−0.4488 0.1231 2.159 0.0191 2 0 WCM207 8 39233365 39380308 −2.2896 NA NANA NA NA WCM207 8 39416136 94777889 −0.4553 0.114 2.1156 0.0488 2 0WCM207 8 94781747 146279475 0.3058 1.0922 2.132 2.132 2 2 WCM207 9 1488033364781 −0.4803 0.079 2.0705 0.0421 2 0 WCM207 9 33366691 1411075450.2527 1.0282 2.0395 2.0395 2 2 WCM207 X 2700125 154493589 0.2443 1.018NA NA NA NA WCM207_X1_1 1 721476 1670402 −0.1701 0.5123 1.8932 0.9595 21 WCM207_X1_1 1 1684395 2268211 −0.707 −0.0292 NA NA NA NA WCM207_X1_1 12288949 3350369 −0.1469 0.5356 1.8437 1.0555 2 1 WCM207_X1_1 1 33799753649951 −1.6394 −0.9752 NA NA NA NA WCM207_X1_1 1 3662242 3784600−0.0834 0.5996 NA NA NA NA WCM207_X1_1 1 3786189 79474645 0.3332 1.01863.0459 1.0059 3 1 WCM207_X1_1 1 82302705 84880488 −0.0437 0.6396 NA NANA NA WCM207_X1_1 1 84944989 145578433 −0.0593 0.6238 2.0993 0.9826 2 1WCM207_X1_1 1 145578668 213405588 −0.0525 0.6306 3.0755 0.0211 3 0WCM207_X1_1 1 213414282 249212557 −0.5724 0.1067 2.1418 0.0116 2 0WCM207_X1_1 10 225988 135440090 −0.6821 −0.004 1.9844 0.01 2 0WCM207_X1_1 11 193151 134856542 0.3612 1.0468 2.0846 2.0472 2 2WCM207_X1_1 12 148673 9847457 −0.3758 0.3051 1.517 0.954 2 1 WCM207_X1_112 9871292 24736882 −1.5828 −0.9175 1.049 0.0099 1 0 WCM207_X1_1 1224970959 133810935 −0.363 0.318 1.5168 0.9764 2 1 WCM207_X1_1 1319600159 35739231 0.2888 0.974 1.984 1.9445 2 2 WCM207_X1_1 13 35743126115089411 −0.6807 −0.0026 1.9853 0.0111 2 0 WCM207_X1_1 14 19377733107283063 0.2734 0.9585 1.9433 1.9433 2 2 WCM207_X1_1 15 20170150102506276 −0.6753 0.0029 1.0789 0.9251 1 1 WCM207_X1_1 16 67604 218175250.268 0.9531 1.9535 1.9185 2 2 WCM207_X1_1 16 21847295 22339835 −0.67310.005 NA NA NA NA WCM207_X1_1 16 22343384 29001519 0.2725 0.9576 1.9851.8991 2 2 WCM207_X1_1 16 29086429 29974525 −0.7341 −0.0566 NA NA NA NAWCM207_X1_1 16 29974838 47733249 0.1986 0.8833 1.9133 1.776 2 2WCM207_X1_1 16 48117824 52502463 0.2188 0.9036 NA NA NA NA WCM207_X1_116 52553356 90233627 −0.6713 0.0068 1.9891 0.0203 2 0 WCM207_X1_1 17131595 18226310 −0.6999 −0.022 1.9499 0.0197 2 0 WCM207_X1_1 17 1823209640004449 0.2709 0.956 1.9672 1.9126 2 2 WCM207_X1_1 17 40024093 43585632−0.6849 −0.0069 1.9683 0.0221 2 0 WCM207_X1_1 17 43922774 810834550.2704 0.9555 1.947 1.9314 2 2 WCM207_X1_1 18 48987 13682036 0.27770.9628 1.9922 1.906 2 2 WCM207_X1_1 18 13731608 15006148 −0.6101 0.0686NA NA NA NA WCM207_X1_1 18 18539817 31463382 0.2863 0.9715 2.0397 1.8822 2 WCM207_X1_1 18 31523089 78005199 −0.6836 −0.0056 1.9712 0.0211 2 0WCM207_X1_1 19 281506 1026720 0.2075 0.8923 1.899 1.8132 2 2 WCM207_X1_119 1031109 3121109 −0.7328 −0.0553 1.9154 0.0093 2 0 WCM207_X1_1 193136493 16977327 0.2581 0.9431 1.9305 1.915 2 2 WCM207_X1_1 19 1698028717438128 −0.7058 −0.028 1.9518 0.0097 2 0 WCM207_X1_1 19 1743834039687733 0.2564 0.9414 1.9416 1.8992 2 2 WCM207_X1_1 19 3968792942754695 −0.6964 −0.0185 1.9636 0.0108 2 0 WCM207_X1_1 19 4279102342796956 0.2443 0.9292 NA NA NA NA WCM207_X1_1 19 42797159 44174243−0.7563 −0.0791 1.8718 0.0215 2 0 WCM207_X1_1 19 44222896 590839700.2375 0.9224 1.9105 1.88 2 2 WCM207_X1_1 2 41623 71429659 −0.66760.0106 1.0236 0.9911 1 1 WCM207_X1_1 2 71576002 73118645 −1.5991 −0.93410.9838 0.063 1 0 WCM207_X1_1 2 73143923 73635855 −0.6715 0.0066 NA NA NANA WCM207_X1_1 2 73646260 74692039 −1.6077 −0.9428 1.0298 0.0106 1 0WCM207_X1_1 2 74699492 85875915 −0.4137 0.2668 1.424 0.9823 1 1WCM207_X1_1 2 85888593 86378421 −1.5773 −0.9119 NA NA NA NA WCM207_X1_12 86385743 150320685 −0.4027 0.2779 1.446 0.9789 1 1 WCM207_X1_1 2150325236 152117867 −1.5639 −0.8982 NA NA NA NA WCM207_X1_1 2 152127368152586147 −0.412 0.2685 NA NA NA NA WCM207_X1_1 2 152589640 152830214−1.2938 −0.6235 NA NA NA NA WCM207_X1_1 2 152954898 242946616 −0.39880.2818 1.4486 0.9828 1 1 WCM207_X1_1 20 68375 62919134 0.2666 0.95171.9574 1.9108 2 2 WCM207_X1_1 21 9826203 48084277 0.2634 0.9484 1.95691.9026 2 2 WCM207_X1_1 22 16287434 51215134 −0.6945 −0.0166 1.95730.0199 2 0 WCM207_X1_1 3 239350 45160010 0.2844 0.9695 1.9838 1.9326 2 2WCM207_X1_1 3 45187717 46401182 −0.6467 0.0317 NA NA NA NA WCM207_X1_1 346414687 47371527 0.3024 0.9876 NA NA NA NA WCM207_X1_1 3 4737468449004575 −0.6836 −0.0056 NA NA NA NA WCM207_X1_1 3 49005971 718307390.2933 0.9785 2.0061 1.9348 2 2 WCM207_X1_1 3 72427624 72881603 −0.57720.1018 NA NA NA NA WCM207_X1_1 3 72890204 195701321 0.2941 0.9793 1.97161.9716 2 2 WCM207_X1_1 3 195702579 196311060 −0.6326 0.0459 NA NA NA NAWCM207_X1_1 3 196381422 197894712 0.2701 0.9552 NA NA NA NA WCM207_X1_14 59339 1107212 −0.6596 0.0186 2.0095 0.0165 2 0 WCM207_X1_1 4 11613957461784 0.2724 0.9575 1.942 1.942 2 2 WCM207_X1_1 4 7533287 26491818−0.7144 −0.0367 1.9363 0.0135 2 0 WCM207_X1_1 4 26585876 53463887 0.28080.966 1.9848 1.922 2 2 WCM207_X1_1 4 53464785 62936572 −0.7037 −0.02591.9498 0.0147 2 0 WCM207_X1_1 4 62937422 68355783 0.3478 1.0332 NA NA NANA WCM207_X1_1 4 68357940 69870670 −0.7374 −0.0599 NA NA NA NAWCM207_X1_1 4 69874614 87610237 0.2836 0.9688 1.9867 1.9276 2 2WCM207_X1_1 4 87614754 104101545 −0.6678 0.0104 1.9859 0.0286 2 0WCM207_X1_1 4 104102593 146101102 0.277 0.9621 1.9795 1.9168 2 2WCM207_X1_1 4 146435975 190426502 −0.665 0.0132 2.0071 0.0113 2 0WCM207_X1_1 5 140579 32108079 0.0735 0.7575 1.9134 1.4678 2 1WCM207_X1_1 5 32126441 33446771 −0.6641 0.0141 NA NA NA NA WCM207_X1_1 533448684 180661992 0.2757 0.9609 1.9543 1.9386 2 2 WCM207_X1_1 5180662380 180687773 0.0785 0.7625 NA NA NA NA WCM207_X1_1 6 20353534855689 0.618 1.3047 3.0632 1.8775 3 2 WCM207_X1_1 6 34935070 36063792−0.6523 0.026 NA NA NA NA WCM207_X1_1 6 36068017 45922958 0.2641 0.94921.9483 1.9133 2 2 WCM207_X1_1 6 46047538 170892614 −0.1238 0.5589 1.93591.0104 2 1 WCM207_X1_1 7 193253 158937135 0.1501 0.8345 1.9196 1.647 2 2WCM207_X1_1 8 190897 94777692 −0.4771 0.2029 2.2888 0.0131 2 0WCM207_X1_1 8 94784839 142524822 0.3978 1.0835 2.1447 2.0936 2 2WCM207_X1_1 8 142528477 143447280 −0.6667 0.0115 NA NA NA NA WCM207_X1_18 143545903 146279416 0.3488 1.0343 2.2745 1.8217 2 2 WCM207_X1_1 9116887 33364754 −0.5511 0.1282 2.174 0.012 2 0 WCM207_X1_1 9 33366722141111414 0.3258 1.0111 2.0277 2.0033 2 2 WCM207_X1_1 X 2700146154509348 0.2372 0.9221 NA NA NA NA WCM212 1 14907 1118275 −0.09380.5429 1.6532 1.2606 2 1 WCM212 1 1119400 145474295 −0.3189 0.19151.1419 1.1419 1 1 WCM212 1 145474325 249213967 −0.0023 0.6779 1.59981.5998 2 2 WCM212 10 226116 105107185 −0.3092 0.2073 2.3043 0.0048 2 0WCM212 10 105108455 105133335 −1.5166 −3.4838 NA NA NA NA WCM212 10105138095 135439016 −0.2747 0.263 2.3775 0.0224 2 0 WCM212 11 1930962946374 0.1309 0.8675 2.4388 1.2103 2 1 WCM212 11 2950322 208692340.0215 0.7123 1.9692 1.3077 2 1 WCM212 11 20869336 102393971 0.1150.8453 1.7966 1.7966 2 2 WCM212 11 102394175 134090538 0.2252 0.99761.9967 1.9967 2 2 WCM212 11 134095110 134605916 0.1703 0.9224 2.02881.7616 2 2 WCM212 12 148465 39046712 −0.0564 0.5986 1.5143 1.5143 2 2WCM212 12 39046800 46623349 0.4889 1.3461 3.47 1.6147 3 2 WCM212 1246633510 133810780 −0.1068 0.5234 1.4374 1.4374 1 1 WCM212 13 19041937115089411 −0.451 −0.0312 1.961 −0.0039 2 0 WCM212 14 19110343 449764050.0987 0.8224 1.7683 1.7683 2 2 WCM212 14 45333758 104245153 0.00430.6874 1.6104 1.6104 2 2 WCM212 14 104251302 107283274 0.1704 0.92241.911 1.8796 2 2 WCM212 15 20084088 41071399 −0.0391 0.6241 1.54121.5412 2 2 WCM212 15 41071816 73564881 −0.2461 0.3086 1.2385 1.2385 1 1WCM212 15 73566192 102514188 −0.1149 0.5113 1.4253 1.4253 1 1 WCM212 1664401 46532056 0.0882 0.8075 2.5667 0.9337 3 1 WCM212 16 4653406090260461 −0.3473 0.1448 1.1055 1.1055 1 1 WCM212 17 131595 21175998−0.2928 0.2339 2.3503 0.0017 2 0 WCM212 17 21201719 81187930 0.12230.8555 1.8094 1.8094 2 2 WCM212 18 47632 14124411 −0.0559 0.5993 1.52841.5016 2 2 WCM212 18 14132231 78005146 −0.223 0.345 1.2702 1.2702 1 1WCM212 19 105021 1037831 0.3322 1.1416 2.7337 1.6788 3 2 WCM212 191041340 24310554 −0.0741 0.5724 2.9618 0.0122 3 0 WCM212 19 2431077440197844 0.64 1.5376 3.799 2.0071 4 2 WCM212 19 40199806 41634029 1.292.3125 7.9045 2.0307 8 2 WCM212 19 41697297 59093645 −0.0144 0.66031.5804 1.5804 2 2 WCM212 2 41686 39998631 0.0651 0.7749 1.711 1.711 2 2WCM212 2 40339627 43986123 −0.4792 −0.0806 1.9225 −0.0312 2 0 WCM212 243989475 65245765 0.0393 0.7379 1.6677 1.6677 2 2 WCM212 2 6524806471753481 −0.4744 −0.0722 1.9095 −0.0071 2 0 WCM212 2 71755439 1284091270.0746 0.7883 1.7271 1.7271 2 2 WCM212 2 128409268 240984637 −0.02570.6437 1.5624 1.5624 2 2 WCM212 2 240984789 243036990 0.0538 0.75871.7668 1.617 2 2 WCM212 20 68427 10393154 0.4078 1.2411 2.3638 2.3638 22 WCM212 20 10393469 60739295 0.2426 1.0214 2.0298 2.0298 2 2 WCM212 2060747704 62934592 0.3514 1.167 2.2454 2.2454 2 2 WCM212 21 959027139947608 0.1048 0.8309 1.7789 1.7789 2 2 WCM212 21 40177325 42866524−0.4685 −0.0617 1.875 0.0413 2 0 WCM212 21 42870037 48084210 0.11960.8517 1.8046 1.8046 2 2 WCM212 22 16159031 17219250 −0.055 0.6007 NA NANA NA WCM212 22 17280746 28503098 0.1104 0.8388 2.6177 0.9594 3 1 WCM21222 28503344 51223730 −0.1184 0.506 1.8919 0.9484 2 1 WCM212 3 23949575469116 −0.12 0.5037 1.4178 1.4178 1 1 WCM212 3 75470091 1978968010.2418 1.0202 2.2952 1.7612 2 2 WCM212 4 53346 46042429 −0.4236 0.01611.0112 1.0112 1 1 WCM212 4 46043100 70261534 −0.1549 0.4506 1.36661.3666 1 1 WCM212 4 70261601 76957171 0.0826 0.7996 1.7406 1.7406 2 2WCM212 4 76997052 120528200 −0.2342 0.3274 1.2547 1.2547 1 1 WCM212 4120528327 184243528 −0.3522 0.1367 1.0994 1.0994 1 1 WCM212 4 184256418190878479 −0.6848 −0.4661 1.041 0.4068 1 0 WCM212 5 90697 524029160.4649 1.3152 2.5013 2.4756 3 2 WCM212 5 52404480 143855184 −0.4441−0.0192 1.9449 0.0287 2 0 WCM212 5 144577493 180687808 0.4094 1.24322.3673 2.3673 2 2 WCM212 6 203516 11306330 −0.5066 −0.1293 1.7794 0.04922 0 WCM212 6 11538569 27876763 0.0507 0.7543 1.6868 1.6868 2 2 WCM212 627879080 62757794 0.207 0.9728 1.9626 1.9626 2 2 WCM212 6 62887207170892821 0.0322 0.7278 1.6561 1.6561 2 2 WCM212 7 195606 637967440.2002 0.9635 1.974 1.9259 2 2 WCM212 7 63797256 128363212 0.0809 0.79731.7378 1.7378 2 2 WCM212 7 128364895 158937185 0.2196 0.99 2.0647 1.90752 2 WCM212 8 163527 35402086 −0.5623 −0.2307 0.8664 0.838 1 1 WCM212 835425681 125551423 0.4589 1.3076 2.4753 2.4753 2 2 WCM212 8 125555427125989339 2.585 3.7271 NA NA NA NA WCM212 8 125989637 144351632 0.51441.3789 2.6007 2.6007 3 3 WCM212 8 144357021 144407620 2.3154 3.4412 NANA NA NA WCM212 8 144411658 146279416 0.3996 1.2304 2.3463 2.3463 2 2WCM212 9 116873 12821387 −0.1467 0.463 1.473 1.2838 1 1 WCM212 912821770 37842209 0.1807 0.9367 1.9142 1.9142 2 2 WCM212 9 3785481839178322 0.0557 0.7614 NA NA NA NA WCM212 9 39355656 132576494 −0.16030.4422 1.3587 1.3587 1 1 WCM212 9 132580791 141107519 0.0697 0.78131.7187 1.7187 2 2 WCM212 X 2700162 68061897 0.1449 0.8871 NA NA NA NAWCM212 X 68381729 154493484 −0.077 0.568 NA NA NA NA WCM212_Z2_1 1 69590145115810 −0.6242 −0.0113 1.085 0.8995 1 1 WCM212_Z2_1 1 145209427249212557 −0.0932 0.5634 1.9618 0.9937 2 1 WCM212_Z2_1 10 225981135440105 −0.6197 −0.0062 1.9808 0.0106 2 0 WCM212_Z2_1 11 193150134856556 0.2525 0.9296 1.9207 1.8887 2 2 WCM212_Z2_1 12 148639133810926 −0.115 0.5402 1.962 0.9463 2 1 WCM212_Z2_1 13 19600515115089411 −0.6215 −0.0082 1.9869 0.0017 2 0 WCM212_Z2_1 14 19377727107283063 −0.1087 0.5469 1.9554 0.9665 2 1 WCM212_Z2_1 15 2017000341556373 −0.1363 0.5174 1.8935 0.9692 2 1 WCM212_Z2_1 15 4156280273076410 −0.6202 −0.0068 1.0194 0.9712 1 1 WCM212_Z2_1 15 73408967101427822 −0.1384 0.5151 1.8784 0.9799 2 1 WCM212_Z2_1 15 101432288102514214 0.2364 0.9126 2.0726 1.6922 2 2 WCM212_Z2_1 16 67604 47196555−0.1193 0.5355 1.9465 0.9525 2 1 WCM212_Z2_1 16 47252840 90233642−0.6327 −0.0205 1.0716 0.9002 1 1 WCM212_Z2_1 17 131595 21191381 −0.6827−0.0757 1.8908 0.0069 2 0 WCM212_Z2_1 17 21194852 81083455 0.2063 0.88091.859 1.8241 2 2 WCM212_Z2_1 18 48959 78005226 −0.0845 0.5727 1.98060.994 2 1 WCM212_Z2_1 19 281404 1041928 0.6196 1.3134 2.984 1.9865 3 2WCM212_Z2_1 19 1042104 24310723 −0.0543 0.6049 3.0434 −0.0017 3 0WCM212_Z2_1 19 29567134 40199954 1.1032 1.8132 5.1148 1.9136 5 2WCM212_Z2_1 19 40222033 41249826 2.1874 2.9187 13.2077 1.9159 13  2WCM212_Z2_1 19 41250094 41633847 1.7558 2.4805 NA NA NA NA WCM212_Z2_119 41699321 59083929 −0.1109 0.5445 1.9195 0.9975 2 1 WCM212_Z2_1 241613 39998733 0.2967 0.976 1.967 1.967 2 2 WCM212_Z2_1 2 4034253343973047 −0.6386 −0.0271 1.9601 0.0026 2 0 WCM212_Z2_1 2 4398078044446027 0.3357 1.0169 NA NA NA NA WCM212_Z2_1 2 44457576 652453480.2917 0.9707 1.9804 1.9392 2 2 WCM212_Z2_1 2 65245810 72359573 −0.6271−0.0144 1.9799 2.00E−04 2 0 WCM212_Z2_1 2 72359737 118577231 0.27 0.94791.9635 1.8946 2 2 WCM212_Z2_1 2 118578821 242946597 −0.0666 0.59182.0162 0.998 2 1 WCM212_Z2_1 20 68375 11904301 0.5784 1.2704 2.83681.988 3 2 WCM212_Z2_1 20 12990016 43399941 0.2914 0.9704 1.98 1.9388 2 2WCM212_Z2_1 20 43530369 62904866 0.5848 1.2772 2.8928 1.9544 3 2WCM212_Z2_1 21 9826230 39822803 0.1749 0.8478 1.8282 1.7712 2 2WCM212_Z2_1 21 39947601 42870093 −0.7515 −0.1518 1.8292 −0.029 2 0WCM212_Z2_1 21 43133046 48084210 0.1851 0.8586 1.8534 1.7731 2 2WCM212_Z2_1 22 16287470 28559401 0.2581 0.9355 2.8478 0.9772 3 1WCM212_Z2_1 22 28692190 51215153 −0.1184 0.5364 1.9307 0.9701 2 1WCM212_Z2_1 3 239347 75476978 −0.1314 0.5226 1.8864 0.9866 2 1WCM212_Z2_1 3 75478311 112643934 0.2076 0.8822 1.8801 1.8063 2 2WCM212_Z2_1 3 112647672 197894726 0.4944 1.1829 2.6968 1.8439 3 2WCM212_Z2_1 4 59331 17876703 −0.6728 −0.0648 1.0658 0.8464 1 1WCM212_Z2_1 4 17885400 23815522 −1.3699 −0.8576 NA NA NA NA WCM212_Z2_14 23815924 26241363 −0.5741 0.0438 NA NA NA NA WCM212_Z2_1 4 2627427430724790 −1.3496 −0.8338 NA NA NA NA WCM212_Z2_1 4 30725087 71062426−0.6242 −0.0112 1.0076 0.977 1 1 WCM212_Z2_1 4 71063722 120987875−0.1261 0.5283 1.9647 0.9198 2 1 WCM212_Z2_1 4 121616352 124235105−0.6188 −0.0052 NA NA NA NA WCM212_Z2_1 4 124323012 128584580 −0.12130.5334 NA NA NA NA WCM212_Z2_1 4 128590245 184368308 −0.5825 0.03461.0501 0.9984 1 1 WCM212_Z2_1 4 184368582 185350159 −1.3567 −0.8421 NANA NA NA WCM212_Z2_1 4 185550524 186097061 −0.4836 0.1427 NA NA NA NAWCM212_Z2_1 4 186111299 190426570 −1.4686 −0.9748 1.0388 −0.0211 1 0WCM212_Z2_1 5 140666 52405544 0.2868 0.9656 1.9959 1.9098 2 2WCM212_Z2_1 5 52778714 143853636 −0.6146 −7.00E−04 1.9859 0.0131 2 0WCM212_Z2_1 5 145144521 180687776 0.2819 0.9605 1.9562 1.9357 2 2WCM212_Z2_1 6 203475 11565979 −0.6182 −0.0046 1.9895 0.0041 2 0WCM212_Z2_1 6 11575661 170893415 0.2176 0.8928 1.8685 1.845 2 2WCM212_Z2_1 7 193222 158937400 0.3149 0.9951 2.0183 1.9681 2 2WCM212_Z2_1 8 190908 35650786 −0.6523 −0.0421 0.9873 0.9552 1 1WCM212_Z2_1 8 36641976 146279507 0.2723 0.9503 2.8747 0.9898 3 1WCM212_Z2_1 9 116902 69256890 0.2676 0.9454 1.952 1.8994 2 2 WCM212_Z2_19 71144493 132576451 −0.1083 0.5473 1.9309 0.9917 2 1 WCM212_Z2_1 9132581031 141111414 0.2607 0.9382 1.9161 1.9161 2 2 WCM212_Z2_1 X2700145 154509348 0.2483 0.9251 NA NA NA NA WCM213 1 14930 236093330.0663 0.2994 1.2306 1.2306 1 1 WCM213 1 23636234 156737969 −0.0097−0.155 0.8981 0.8981 1 1 WCM213 1 156752048 249213967 0.0872 0.40631.3253 1.3253 1 1 WCM213 10 225958 135438959 −0.0092 −0.1512 0.90050.9005 1 1 WCM213 11 193112 62334787 0.0062 −0.0496 0.9662 0.9662 1 1WCM213 11 62335042 65835438 −0.23 −5.1812 0.0276 0.0276 0 0 WCM213 1165836198 134605959 −0.01 −0.1572 0.8967 0.8967 1 1 WCM213 12 148576133810869 −0.0231 −0.2494 0.8412 0.8412 1 1 WCM213 13 19041994 115089411−0.0566 −0.5118 0.7014 0.7014 1 1 WCM213 14 19110251 107283270 −0.006−0.1298 0.9139 0.9139 1 1 WCM213 15 20084061 102514249 0.0099 −0.0260.9821 0.9821 1 1 WCM213 16 67256 90168697 0.0127 −0.008 0.9945 0.9945 11 WCM213 17 262900 81187853 −0.0131 −0.1784 0.8837 0.8837 1 1 WCM213 1847806 78005203 −0.0209 −0.2334 0.8506 0.8506 1 1 WCM213 19 10505059093645 −0.0374 −0.3562 0.7812 0.7812 1 1 WCM213 2 41612 243052762−0.0176 −0.2097 0.8647 0.8647 1 1 WCM213 20 68340 62934592 0.0378 0.14291.1041 1.1041 1 1 WCM213 21 9590301 48084196 0.036 0.1325 1.0962 1.09621 1 WCM213 22 16159060 51219090 0.023 0.0555 1.0392 1.0392 1 1 WCM213 3239524 121591830 −0.0048 −0.1215 0.9193 0.9193 1 1 WCM213 3 121605171140397288 0.1466 0.6795 1.6015 1.6015 2 2 WCM213 3 140401351 197896818−0.0346 −0.3343 0.7932 0.7932 1 1 WCM213 4 53377 190903980  6.00E−04−0.0859 0.9422 0.9422 1 1 WCM213 5 90647 55238586 0.051 0.2168 1.16221.1622 1 1 WCM213 5 55240490 145849065 −0.0528 −0.4796 0.7172 0.7172 1 1WCM213 5 145849345 180687854 0.0524 0.2249 1.1687 1.1687 1 1 WCM213 6203479 170892848 −0.0249 −0.2627 0.8336 0.8336 1 1 WCM213 7 193222158937072 0.0611 0.2717 1.2072 1.2072 1 1 WCM213 8 163527 65489024−0.0204 −0.2299 0.8527 0.8527 1 1 WCM213 8 65489135 145666371 0.15110.6986 1.623 1.623 2 2 WCM213 8 145667516 146279480 −0.0107 −0.1620.9921 0.7955 1 1 WCM213 9 116800 141107533 −9.00E−04 −0.0955 0.9360.936 1 1 WCM213 X 2700202 154493478 −0.0371 −0.354 NA NA NA NAWCM213_X1_1 1 721415 880916 0.317 NA NA NA NA NA WCM213_X1_1 1 88162710463163 −0.0117 NA NA NA NA NA WCM213_X1_1 1 10464227 70883666 −0.149NA NA NA NA NA WCM213_X1_1 1 70887343 102290624 0.004 NA NA NA NA NAWCM213_X1_1 1 102296279 120611454 −0.3643 NA NA NA NA NA WCM213_X1_1 1120611948 150913872 0.7462 NA NA NA NA NA WCM213_X1_1 1 150915083242042621 0.4759 NA NA NA NA NA WCM213_X1_1 1 242045259 249212373 0.6624NA NA NA NA NA WCM213_X1_1 10 255940 81700492 −0.0843 NA NA NA NA NAWCM213_X1_1 10 81701219 105203787 −0.5466 NA NA NA NA NA WCM213_X1_1 10105204367 135440117 −0.2389 NA NA NA NA NA WCM213_X1_1 11 19311259516849 −0.1067 NA NA NA NA NA WCM213_X1_1 11 59523088 65888527 −0.3477NA NA NA NA NA WCM213_X1_1 11 65960986 68177550 0.166 NA NA NA NA NAWCM213_X1_1 11 68178928 134180978 −0.117 NA NA NA NA NA WCM213_X1_1 11134182254 134856559 0.0839 NA NA NA NA NA WCM213_X1_1 12 148642110295384 −0.2751 NA NA NA NA NA WCM213_X1_1 12 110295991 133318071−0.0202 NA NA NA NA NA WCM213_X1_1 12 133318406 133810868 −0.2612 NA NANA NA NA WCM213_X1_1 13 19600515 115089411 −0.1374 NA NA NA NA NAWCM213_X1_1 14 19377698 73581029 −0.0709 NA NA NA NA NA WCM213_X1_1 1473614814 75142480 0.3656 NA NA NA NA NA WCM213_X1_1 14 75142987 752645650.1564 NA NA NA NA NA WCM213_X1_1 14 75264735 103355925 −0.1102 NA NA NANA NA WCM213_X1_1 14 103357737 107283087 0.1409 NA NA NA NA NAWCM213_X1_1 15 20170134 41030170 −0.1495 NA NA NA NA NA WCM213_X1_1 1541030715 60656628 −0.0244 NA NA NA NA NA WCM213_X1_1 15 60666686102517678 −0.1112 NA NA NA NA NA WCM213_X1_1 16 67604 2164652 −0.0975 NANA NA NA NA WCM213_X1_1 16 2166628 2321748 0.0867 NA NA NA NA NAWCM213_X1_1 16 2326679 21156619 0.1496 NA NA NA NA NA WCM213_X1_1 1621157383 87448043 0.0357 NA NA NA NA NA WCM213_X1_1 16 87448935 90162182−0.0381 NA NA NA NA NA WCM213_X1_1 17 131595 7230144 0.0217 NA NA NA NANA WCM213_X1_1 17 7230486 15848844 −0.1972 NA NA NA NA NA WCM213_X1_1 1715878276 16734839 −0.7701 NA NA NA NA NA WCM213_X1_1 17 1673564319607457 −0.2538 NA NA NA NA NA WCM213_X1_1 17 19607989 40629672 0.0992NA NA NA NA NA WCM213_X1_1 17 40630510 42295575 −0.2195 NA NA NA NA NAWCM213_X1_1 17 42327850 44954069 0.1555 NA NA NA NA NA WCM213_X1_1 1744962398 64800116 0.3046 NA NA NA NA NA WCM213_X1_1 17 64873552 810835260.1014 NA NA NA NA NA WCM213_X1_1 18 48202 33703547 0.1314 NA NA NA NANA WCM213_X1_1 18 33704532 78005215 −0.1502 NA NA NA NA NA WCM213_X1_119 281405 8842313 −0.2977 NA NA NA NA NA WCM213_X1_1 19 8931884 43441188−0.0778 NA NA NA NA NA WCM213_X1_1 19 43514159 43708392 −0.145 NA NA NANA NA WCM213_X1_1 19 43709006 59083968 0.2312 NA NA NA NA NA WCM213_X1_12 41612 33526713 −0.0085 NA NA NA NA NA WCM213_X1_1 2 33534529 75425728−0.2991 NA NA NA NA NA WCM213_X1_1 2 75425942 84869148 −0.1128 NA NA NANA NA WCM213_X1_1 2 84880445 209358277 0.0905 NA NA NA NA NA WCM213_X1_12 209436747 242946616 −0.2041 NA NA NA NA NA WCM213_X1_1 20 6836349219097 0.144 NA NA NA NA NA WCM213_X1_1 20 49219132 62863548 0.5424 NANA NA NA NA WCM213_X1_1 20 62867958 62904847 0.0143 NA NA NA NA NAWCM213_X1_1 21 9826225 40177454 0.1639 NA NA NA NA NA WCM213_X1_1 2140177902 43164295 −0.4651 NA NA NA NA NA WCM213_X1_1 21 4316598648084282 0.3015 NA NA NA NA NA WCM213_X1_1 22 16287446 51215142 −0.0118NA NA NA NA NA WCM213_X1_1 3 239431 93772078 −0.0504 NA NA NA NA NAWCM213_X1_1 3 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−0.1495 NA NA NA NA NA WCM213_Z13_1 1 226497483 2492124290.3001 NA NA NA NA NA WCM213_Z13_1 10 255871 81697868 −0.0208 NA NA NANA NA WCM213_Z13_1 10 81700493 105108750 −0.3724 NA NA NA NA NAWCM213_Z13_1 10 105110649 135440105 −0.0791 NA NA NA NA NA WCM213_Z13_111 193112 34378465 −0.1458 NA NA NA NA NA WCM213_Z13_1 11 3437858059480980 −0.0049 NA NA NA NA NA WCM213_Z13_1 11 59481155 65961018−0.2449 NA NA NA NA NA WCM213_Z13_1 11 65977871 69978074 0.0858 NA NA NANA NA WCM213_Z13_1 11 69995893 76076986 −0.1394 NA NA NA NA NAWCM213_Z13_1 11 76091814 83874546 0.1448 NA NA NA NA NA WCM213_Z13_1 1183877999 134856559 −0.1625 NA NA NA NA NA WCM213_Z13_1 12 148644 4162490.0655 NA NA NA NA NA WCM213_Z13_1 12 416977 14664562 −0.0417 NA NA NANA NA WCM213_Z13_1 12 14688651 68618970 −0.1765 NA NA NA NA NAWCM213_Z13_1 12 68619233 110246136 −0.0511 NA NA NA NA NA WCM213_Z13_112 110252458 111872722 0.1733 NA NA NA NA NA WCM213_Z13_1 12 111884608113496222 0.4112 NA NA NA NA NA WCM213_Z13_1 12 113515269 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6 203515 10529797 −0.2725 NA NA NA NA NA WCM213_Z13_1 610529956 10830846 −0.1236 NA NA NA NA NA WCM213_Z13_1 6 1087427218406327 0.1965 NA NA NA NA NA WCM213_Z13_1 6 18427820 28963248 −0.197NA NA NA NA NA WCM213_Z13_1 6 28963364 36564739 0.1187 NA NA NA NA NAWCM213_Z13_1 6 36566629 41900435 −0.1213 NA NA NA NA NA WCM213_Z13_1 641903783 49580247 0.1181 NA NA NA NA NA WCM213_Z13_1 6 49582512 74520803−0.0949 NA NA NA NA NA WCM213_Z13_1 6 74521964 80201400 −0.28 NA NA NANA NA WCM213_Z13_1 6 80202326 99374815 −0.2542 NA NA NA NA NAWCM213_Z13_1 6 99572563 118886989 −0.5112 NA NA NA NA NA WCM213_Z13_1 6118887303 170893407 −0.2006 NA NA NA NA NA WCM213_Z13_1 7 19345137136228 −0.0214 NA NA NA NA NA WCM213_Z13_1 7 37172789 37903060 0.5554NA NA NA NA NA WCM213_Z13_1 7 37905208 45108060 0.4152 NA NA NA NA NAWCM213_Z13_1 7 45109511 81335063 0.5599 NA NA NA NA NA WCM213_Z13_1 781335673 99375666 0.2733 NA NA NA NA NA WCM213_Z13_1 7 99377661110526661 0.4698 NA NA NA NA NA WCM213_Z13_1 7 110603137 158937375 0.3NA NA NA NA NA WCM213_Z13_1 8 190908 22675196 −0.6668 NA NA NA NA NAWCM213_Z13_1 8 22777766 37333471 −0.4215 NA NA NA NA NA WCM213_Z13_1 837374128 38775571 0.5906 NA NA NA NA NA WCM213_Z13_1 8 38793527 431571130.1777 NA NA NA NA NA WCM213_Z13_1 8 43171038 50449788 −0.1825 NA NA NANA NA WCM213_Z13_1 8 51306813 64100298 0.3216 NA NA NA NA NAWCM213_Z13_1 8 65286010 67547149 0.9455 NA NA NA NA NA WCM213_Z13_1 867547257 77896016 0.6605 NA NA NA NA NA WCM213_Z13_1 8 77896321 893401940.9933 NA NA NA NA NA WCM213_Z13_1 8 90770338 99468115 0.4532 NA NA NANA NA WCM213_Z13_1 8 99539049 102731537 0.0455 NA NA NA NA NAWCM213_Z13_1 8 102731825 103662579 0.8502 NA NA NA NA NA WCM213_Z13_1 8103663391 142264209 0.4141 NA NA NA NA NA WCM213_Z13_1 8 142264797146279480 0.5117 NA NA NA NA NA WCM213_Z13_1 9 17056 27055662 −0.106 NANA NA NA NA WCM213_Z13_1 9 27056372 69256883 0.1551 NA NA NA NA NAWCM213_Z13_1 9 71144547 113169030 −0.3184 NA NA NA NA NA WCM213_Z13_1 9113169442 132382629 −0.2021 NA NA NA NA NA WCM213_Z13_1 9 132395015133769178 −0.2765 NA NA NA NA NA WCM213_Z13_1 9 133779422 141111414−0.0939 NA NA NA NA NA WCM213_Z13_1 X 2700119 67431965 0.3733 NA NA NANA NA WCM213_Z13_1 X 67454405 154509348 −0.2057 NA NA NA NA NA WCM216 114930 899359 −0.0562 −0.1679 0.9533 0.827 1 1 WCM216 1 899571 355773850.0817 0.1216 1.0988 1.0771 1 1 WCM216 1 35577746 249213961 0.0023−0.0413 0.9718 0.9718 1 1 WCM216 10 225958 135438909 0.0245 0.00531.0037 1.0037 1 1 WCM216 11 128378 134605827 0.0143 −0.0161 0.98890.9889 1 1 WCM216 12 148567 133810704 0.0103 −0.0244 0.9832 0.9832 1 1WCM216 13 19042165 115089411 −0.0019 −0.0502 0.9658 0.9658 1 1 WCM216 1419110174 107283270 0.0016 −0.0428 0.9708 0.9708 1 1 WCM216 15 20083972102506257 0.03 0.0167 1.0116 1.0116 1 1 WCM216 16 83338 90168857 0.015−0.0147 0.9899 0.9899 1 1 WCM216 17 131595 81052551 0.0218 −4.00E−040.9998 0.9998 1 1 WCM216 18 47588 78005115 0.0035 −0.0387 0.9735 0.97351 1 WCM216 19 105021 59093696 0.0115 −0.0221 0.9848 0.9848 1 1 WCM216 241680 243037022 −0.0013 −0.0489 0.9666 0.9666 1 1 WCM216 20 6840662934541 0.0527 0.0633 1.0448 1.0448 1 1 WCM216 21 9590305 41559253−0.0469 −0.1474 0.9168 0.889 1 1 WCM216 21 41559927 47700514 0.12390.2047 1.1524 1.1524 1 1 WCM216 21 47703649 48084207 0.0062 −0.0331.0639 0.8908 1 1 WCM216 22 16159043 51223730 0.0746 0.1076 1.07741.0774 1 1 WCM216 3 239347 197896705 0.0049 −0.0359 0.9754 0.9754 1 1WCM216 4 53349 190882003 −0.0254 −0.1007 0.9326 0.9326 1 1 WCM216 590750 180687828 −0.0123 −0.0724 0.951 0.951 1 1 WCM216 6 203561170893411 −0.0032 −0.0531 0.9639 0.9639 1 1 WCM216 7 193189 1589373750.0163 −0.0119 0.998 0.9856 1 1 WCM216 8 163550 146279514 0.0062 −0.03320.9773 0.9773 1 1 WCM216 9 14822 111625219 −0.0143 −0.0767 0.9482 0.94821 1 WCM216 9 111625520 141015379 0.0775 0.1133 1.0817 1.0817 1 1 WCM2169 141015921 141107533 −0.1788 −0.4553 1.458 6.00E−04 1 0 WCM216 X2700202 154493589 −0.0648 −0.1872 NA NA NA NA WCM216_Z1_1 1 69569249212346 −0.006 NA NA NA NA NA WCM216_Z1_1 10 226016 135440108 −0.0158NA NA NA NA NA WCM216_Z1_1 11 193152 134856597 −0.0069 NA NA NA NA NAWCM216_Z1_1 12 148674 133810703 −0.0061 NA NA NA NA NA WCM216_Z1_1 1319600475 115089411 −0.0367 NA NA NA NA NA WCM216_Z1_1 14 19377703107283027 −0.0054 NA NA NA NA NA WCM216_Z1_1 15 20170029 102506273−0.0127 NA NA NA NA NA WCM216_Z1_1 16 97531 90162166 0.0013 NA NA NA NANA WCM216_Z1_1 17 131595 81083455 0.0052 NA NA NA NA NA WCM216_Z1_1 1848269 78005197 −0.0417 NA NA NA NA NA WCM216_Z1_1 19 281424 590839290.0086 NA NA NA NA NA WCM216_Z1_1 2 41613 242946607 −0.0089 NA NA NA NANA WCM216_Z1_1 20 68351 62904863 −0.0019 NA NA NA NA NA WCM216_Z1_1 219826207 48084281 −6.00E−04 NA NA NA NA NA WCM216_Z1_1 22 1628748051219138 0.0065 NA NA NA NA NA WCM216_Z1_1 3 239443 197896720 −0.0057 NANA NA NA NA WCM216_Z1_1 4 59331 190426502 −0.0268 NA NA NA NA NAWCM216_Z1_1 5 140532 180687803 −0.017 NA NA NA NA NA WCM216_Z1_1 6203510 170893407 −0.0179 NA NA NA NA NA WCM216_Z1_1 7 193265 158937185−0.0118 NA NA NA NA NA WCM216_Z1_1 8 190907 61482596 −0.0488 NA NA NA NANA WCM216_Z1_1 8 61484612 135621053 0.0357 NA NA NA NA NA WCM216_Z1_1 8135622763 146279544 −0.0539 NA NA NA NA NA WCM216_Z1_1 9 17066 141111414−0.0144 NA NA NA NA NA WCM216_Z1_1 X 2700147 154509348 −0.0478 NA NA NANA NA WCM218 1 14930 249213964 0.0263 0.1425 1.1038 1.1038 1 1 WCM218 10226116 135477891 0.0176 0.0797 1.0568 1.0568 1 1 WCM218 11 19313562300042 0.0336 0.1927 1.2369 1.0489 1 1 WCM218 11 62300434 66445317−0.129 −1.6995 0.3919 0.2239 0 0 WCM218 11 66453322 134605959 0.02420.127 1.092 1.092 1 1 WCM218 12 148513 133810769 0.0067 −0.0026 0.99820.9982 1 1 WCM218 13 19041965 115089411 −6.00E−04 −0.0598 0.9594 0.95941 1 WCM218 14 19110251 107283270 0.0069 −8.00E−04 0.9994 0.9994 1 1WCM218 15 20083896 102514188 0.0308 0.1736 1.1278 1.1278 1 1 WCM218 1667591 28931150 0.0152 0.0622 1.044 1.044 1 1 WCM218 16 28935787 46726503−0.1581 −2.5703 0.3536 −0.0169 0 0 WCM218 16 46727031 90260461 0.00880.0136 1.0094 1.0094 1 1 WCM218 17 131595 81187946  8.00E−04 −0.04860.9669 0.9669 1 1 WCM218 18 47654 78005197 0.0076 0.005 1.0034 1.0034 11 WCM218 19 105050 59093645 −0.0524 −0.5361 0.6896 0.6896 1 1 WCM218 241613 243037022 0.0068 −0.0013 0.9991 0.9991 1 1 WCM218 20 6844662934572 0.0357 0.2071 1.1543 1.1543 1 1 WCM218 21 9590311 480842140.0093 0.0173 1.0121 1.0121 1 1 WCM218 22 16159021 51223730 0.03220.1833 1.1355 1.1355 1 1 WCM218 3 239451 197896714 0.0094 0.0183 1.01281.0128 1 1 WCM218 4 53396 190903980 0.0146 0.0571 1.0404 1.0404 1 1WCM218 5 90751 180687804 −0.0014 −0.0661 0.9552 0.9552 1 1 WCM218 6203397 170892918 −3.00E−04 −0.0571 0.9612 0.9612 1 1 WCM218 7 193205158937011 0.012 0.038 1.0267 1.0267 1 1 WCM218 8 163476 146279529 0.00890.0146 1.0102 1.0102 1 1 WCM218 9 15879 141107515 0.0323 0.1843 1.13631.1363 1 1 WCM218 X 2700163 154493601 −0.0584 −0.6014 NA NA NA NAWCM218_Z11_1 1 69592 31187094 −0.4185 −1.0514 1.0263 −0.0613 1 0WCM218_Z11_1 1 31188089 145747046 0.0081 0.0962 1.085 1.0529 1 1WCM218_Z11_1 1 145748529 158605722 0.2868 0.639 2.0548 1.0597 2 1WCM218_Z11_1 1 158606463 205770144 0.2566 0.5846 1.9678 1.0315 2 1WCM218_Z11_1 1 205779231 227921639 0.2583 0.5877 2.2086 0.797 2 1WCM218_Z11_1 1 227922517 228363152 −0.0943 −0.1329 NA NA NA NAWCM218_Z11_1 1 228391808 249212241 0.0985 0.2834 2.4709 −0.0367 2 0WCM218_Z11_1 10 225981 23409768 −0.3891 −0.9503 0.9785 0.0565 1 0WCM218_Z11_1 10 23481591 75898098 0.0365 0.1565 1.3296 0.8996 1 1WCM218_Z11_1 10 75911036 135440081 −0.4467 −1.1536 0.9377 −0.0386 1 0WCM218_Z11_1 11 193102 134856536 −0.0601 −0.0541 0.9807 0.9457 1 1WCM218_Z11_1 12 148673 60162031 −0.0777 −0.0943 0.9648 0.9087 1 1WCM218_Z11_1 12 60165031 133810896 0.22 0.5174 1.925 0.9378 2 1WCM218_Z11_1 13 19600515 19755886 −0.4702 −1.243 NA NA NA NAWCM218_Z11_1 13 19759475 37679268 −0.1453 −0.2551 0.9162 0.7596 1 1WCM218_Z11_1 13 37804353 96261756 −0.3747 −0.9024 0.9954 0.0746 1 0WCM218_Z11_1 13 96263699 115089411 0.5032 1.0051 2.9404 1.0738 3 1WCM218_Z11_1 14 19377711 107283047 −0.0148 0.0466 1.0509 1.0148 1 1WCM218_Z11_1 15 20170150 102514154 0.0024 0.084 1.0828 1.0372 1 1WCM218_Z11_1 16 67604 68725783 −0.003 0.0723 1.0673 1.0355 1 1WCM218_Z11_1 16 68729264 68835716 −2.2104 NA NA NA NA NA WCM218_Z11_1 1668842395 79619821  8.00E−04 0.0805 1.0824 1.0323 1 1 WCM218_Z11_1 1679628419 90108931 −0.3757 −0.9057 1.0448 0.0228 1 0 WCM218_Z11_1 1690109662 90161584 −0.1172 −0.187 NA NA NA NA WCM218_Z11_1 17 13159513977759 −0.343 −0.8007 1.0662 0.0819 1 0 WCM218_Z11_1 17 1398024030771558 0.0014 0.0819 1.0995 1.0174 1 1 WCM218_Z11_1 17 3077400441961452 0.2828 0.6318 2.0429 1.0562 2 1 WCM218_Z11_1 17 4197574542829321 −0.3464 −0.8114 NA NA NA NA WCM218_Z11_1 17 42837130 428550820.4011 0.837 NA NA NA NA WCM218_Z11_1 17 42855228 79099738 0.345 0.74142.2158 1.1277 2 1 WCM218_Z11_1 17 79100235 80992962 0.5769 1.1218 2.2342.1184 2 2 WCM218_Z11_1 17 81006387 81083419 0.7421 1.3721 NA NA NA NAWCM218_Z11_1 18 48221 78005215 −0.0568 −0.0467 0.9966 0.9397 1 1WCM218_Z11_1 19 281404 7795248 −0.3702 −0.8876 1.131 −0.05 1 0WCM218_Z11_1 19 7795940 47589710 −0.0216 0.0319 1.0448 0.9999 1 1WCM218_Z11_1 19 47593410 49004797 −0.3788 −0.916 1.0539 0.0061 1 0WCM218_Z11_1 19 49005758 59083968 −0.0169 0.0421 1.0544 1.0048 1 1WCM218_Z11_1 2 41615 272203 0.0891 0.2645 NA NA NA NA WCM218_Z11_1 2275167 234763031 −0.0134 0.0498 1.0509 1.0193 1 1 WCM218_Z11_1 2234774887 242946597 −0.3842 −0.934 1.0227 0.0242 1 0 WCM218_Z11_1 2068351 62904848  2.00E−04 0.0792 1.0792 1.0336 1 1 WCM218_Z11_1 219826225 48084210 −0.0121 0.0527 1.0688 1.0056 1 1 WCM218_Z11_1 2217060359 51215120 −0.0154 0.0453 1.0567 1.0071 1 1 WCM218_Z11_1 3 23945133907993 −0.2561 −0.5446 0.9755 0.3956 1 0 WCM218_Z11_1 3 35723322190106199 0.0186 0.1186 1.0857 1.0857 1 1 WCM218_Z11_1 3 190120142197894712 −0.2846 −0.6255 1.0746 0.2217 1 0 WCM218_Z11_1 4 59361100479298 −0.0604 −0.0548 0.9802 0.9453 1 1 WCM218_Z11_1 4 100480481187542217 0.2107 0.5002 1.8336 0.9952 2 1 WCM218_Z11_1 4 187542394190426459 0.165 0.4137 NA NA NA NA WCM218_Z11_1 5 140663 148610209−0.0728 −0.0831 0.9614 0.9267 1 1 WCM218_Z11_1 5 148612820 1680968860.2079 0.495 1.8777 0.9409 2 1 WCM218_Z11_1 5 168098235 168195160 0.24880.5704 NA NA NA NA WCM218_Z11_1 5 168199876 180622668 −0.0497 −0.03062.0048 −0.0468 2 0 WCM218_Z11_1 5 180625186 180687808 0.0941 0.2747 NANA NA NA WCM218_Z11_1 6 203695 12122818 −0.4402 −1.1296 0.8164 0.0977 10 WCM218_Z11_1 6 12123218 64356570 −0.0556 −0.044 1.0051 0.9349 1 1WCM218_Z11_1 6 64390027 65300775 −0.4674 −1.2323 NA NA NA NAWCM218_Z11_1 6 65301167 93956647 −0.3915 −0.9585 1.0409 −0.0117 1 0WCM218_Z11_1 6 93965751 170893407 −0.0596 −0.053 0.9902 0.9377 1 1WCM218_Z11_1 7 193245 129765724 −0.0584 −0.0503 1.1517 0.7798 1 1WCM218_Z11_1 7 129769310 158937018 0.3952 0.827 2.0108 1.5373 2 2WCM218_Z11_1 8 190897 280879 0.4834 0.9731 NA NA NA NA WCM218_Z11_1 8328513 19276220 −0.0416 −0.0124 2.0938 −0.111 2 0 WCM218_Z11_1 819277858 35563468 −0.4454 −1.149 0.8859 0.0159 1 0 WCM218_Z11_1 835579745 67352400 −0.0979 −0.1412 0.977 0.8365 1 1 WCM218_Z11_1 867355054 146112284 0.2144 0.507 1.9392 0.903 2 1 WCM218_Z11_1 8146115037 146279529 0.0523 0.1893 NA NA NA NA WCM218_Z11_1 9 170588518143 −0.3488 −0.8188 1.041 0.0928 1 0 WCM218_Z11_1 9 8518395 38527602−0.0743 −0.0866 0.9872 0.8963 1 1 WCM218_Z11_1 9 38527860 1411114140.1734 0.4298 1.7813 0.9128 2 1 WCM218_Z11_1 X 2707711 65819596 −0.105−0.1581 NA NA NA NA WCM218_Z11_1 X 65822515 76938748 0.4655 0.9439 NA NANA NA WCM218_Z11_1 X 76939226 154509348 −0.1015 −0.1499 NA NA NA NAWCM218_Z3_1 1 69592 31186434 −0.4433 −0.8552 1.045 0.0606 1 0WCM218_Z3_1 1 31187146 146232669 −0.0344 0.0029 1.0111 0.9929 1 1WCM218_Z3_1 1 146398506 227348252 0.3067 0.573 1.9856 0.9895 2 1WCM218_Z3_1 1 227381561 228362451 0.0177 0.0962 NA NA NA NA WCM218_Z3_11 228362682 243809321 −0.0587 −0.0416 1.9846 −0.0414 2 0 WCM218_Z3_1 1243858900 249212243 −0.4994 −0.9987 1.0371 −0.0362 1 0 WCM218_Z3_1 10225952 3827207 −0.0655 −0.0541 0.9899 0.9365 1 1 WCM218_Z3_1 10 486721823303037 −0.5063 −1.0167 0.989 −5.00E−04  1 0 WCM218_Z3_1 10 2331954763441055 −0.0728 −0.0675 0.9879 0.9206 1 1 WCM218_Z3_1 10 6344581275863657 0.1074 0.251 1.2282 1.1518 1 1 WCM218_Z3_1 10 75865002 76158233−0.0925 −0.1045 NA NA NA NA WCM218_Z3_1 10 76285109 135440068 −0.4905−0.9751 1.0116 0.0058 1 0 WCM218_Z3_1 11 193127 66481170 −0.041 −0.00921.0136 0.9737 1 1 WCM218_Z3_1 11 66481812 69469088 0.3875 0.6962 2.10311.1374 2 1 WCM218_Z3_1 11 69469211 134856542 −0.0416 −0.0103 1.01830.9676 1 1 WCM218_Z3_1 12 148642 60173356 −0.0427 −0.0123 1.0657 0.91731 1 WCM218_Z3_1 12 62104199 133810869 0.3035 0.5679 1.9816 0.9832 2 1WCM218_Z3_1 13 19600371 32366149 −0.0398 −0.0068 1.2183 0.7722 1 1WCM218_Z3_1 13 32367046 34395385 −0.7409 −1.7505 NA NA NA NA WCM218_Z3_113 34398071 38145574 −0.1893 −0.2921 NA NA NA NA WCM218_Z3_1 13 3815193196264374 −0.5075 −1.0199 0.9757 0.0106 1 0 WCM218_Z3_1 13 96272196115089411 0.4104 0.7306 2.2638 1.0548 2 1 WCM218_Z3_1 14 1937772775138157 −0.0482 −0.0222 1.019 0.9504 1 1 WCM218_Z3_1 14 7513981175421875 −0.4981 −0.995 NA NA NA NA WCM218_Z3_1 14 75469723 107283210−0.0305 0.01 1.0289 0.9851 1 1 WCM218_Z3_1 15 20170150 102514154 −0.0384−0.0043 1.0206 0.9734 1 1 WCM218_Z3_1 16 67604 79245956 −0.0208 0.02741.0339 1.0045 1 1 WCM218_Z3_1 16 79619821 90233627 −0.4618 −0.90161.0483 0.0223 1 0 WCM218_Z3_1 17 131595 13400048 −0.4783 −0.9435 0.98030.0596 1 0 WCM218_Z3_1 17 13446846 30202424 −0.0106 0.0458 1.1322 0.93241 1 WCM218_Z3_1 17 30205278 41961469 0.3249 0.6011 1.9605 1.0732 2 1WCM218_Z3_1 17 41975714 42837180 −0.4728 −0.9294 NA NA NA NA WCM218_Z3_117 42847102 79106464 0.3285 0.6066 2.0517 0.9937 2 1 WCM218_Z3_1 1779107061 81083455 0.6407 1.0622 2.1317 2.0445 2 2 WCM218_Z3_1 18 4826667992954 −0.0516 −0.0284 0.9895 0.9715 1 1 WCM218_Z3_1 18 6799323278005206 −0.466 −0.9122 1.0037 0.059 1 0 WCM218_Z3_1 19 281483 7830099−0.4535 −0.8807 1.0604 0.0258 1 0 WCM218_Z3_1 19 7830571 47597859−0.0258 0.0185 1.0294 0.9965 1 1 WCM218_Z3_1 19 47615692 49001956−0.4852 −0.9614 1.0223 0.0048 1 0 WCM218_Z3_1 19 49002413 59083953−0.0292 0.0123 1.0177 0.9995 1 1 WCM218_Z3_1 2 41609 73989806 −0.0434−0.0136 1.0124 0.9689 1 1 WCM218_Z3_1 2 73993650 74466483 −0.4953−0.9877 NA NA NA NA WCM218_Z3_1 2 74469159 160604812 −0.0523 −0.02980.9957 0.9634 1 1 WCM218_Z3_1 2 160605188 161349869 −0.5083 −1.0221 NANA NA NA WCM218_Z3_1 2 161797513 234839347 −0.0625 −0.0485 0.9991 0.93481 1 WCM218_Z3_1 2 234846108 242946604 −0.4873 −0.9669 0.997 0.0262 1 0WCM218_Z3_1 20 68396 62904847 −0.0299 0.0111 1.0151 1.0004 1 1WCM218_Z3_1 21 9826203 48084277 −0.0405 −0.0081 1.0053 0.9835 1 1WCM218_Z3_1 22 16287481 51215137 −0.0227 0.0241 1.0278 1.0058 1 1WCM218_Z3_1 3 239350 197894713 −0.0417 −0.0104 1.0091 0.9765 1 1WCM218_Z3_1 4 59375 367639 0.131 0.2906 NA NA NA NA WCM218_Z3_1 4 420497100575735 −0.06 −0.0439 0.9789 0.9611 1 1 WCM218_Z3_1 4 100738152190426459 0.2743 0.5224 1.9188 0.9539 2 1 WCM218_Z3_1 5 140684 148521664−0.0491 −0.0239 0.998 0.9691 1 1 WCM218_Z3_1 5 148563110 1691270970.2827 0.5355 1.937 0.9619 2 1 WCM218_Z3_1 5 169129414 180687814 −0.0383−0.0041 1.9883 0.006 2 0 WCM218_Z3_1 6 203545 12089436 −0.2821 −0.48430.9632 0.4665 1 0 WCM218_Z3_1 6 12120127 58250780 −0.0412 −0.0095 1.01340.9735 1 1 WCM218_Z3_1 6 62284302 62757815 −0.2277 −0.3699 NA NA NA NAWCM218_Z3_1 6 62887108 93969182 −0.5103 −1.0275 0.9735 0.0076 1 0WCM218_Z3_1 6 93973575 170893408 −0.0646 −0.0524 0.9821 0.9465 1 1WCM218_Z3_1 7 193265 127031567 −0.0394 −0.0062 1.0175 0.9739 1 1WCM218_Z3_1 7 127222157 139026260 0.289 0.5453 1.974 0.9446 2 1WCM218_Z3_1 7 139030252 158937022 0.5603 0.949 1.9608 1.9003 2 2WCM218_Z3_1 8 190906 328513 0.0979 0.235 NA NA NA NA WCM218_Z3_1 8328616 19456843 0.0171 0.0951 2.164 −0.0278 2 0 WCM218_Z3_1 8 1967509636644853 −0.4757 −0.9369 1.0532 −0.0085 1 0 WCM218_Z3_1 8 3666155667422385 −0.0524 −0.03 1.0549 0.9039 1 1 WCM218_Z3_1 8 67425832146279544 0.3003 0.5629 1.934 1.0204 2 1 WCM218_Z3_1 9 17085 12695819−0.5077 −1.0204 0.9833 0.0026 1 0 WCM218_Z3_1 9 12698568 71155663−0.0579 −0.0401 1.0174 0.9278 1 1 WCM218_Z3_1 9 71395275 1411114140.2949 0.5545 1.926 1.0113 2 1 WCM218_Z3_1 X 2707708 65486503 −0.1034−0.1251 NA NA NA NA WCM218_Z3_1 X 65819332 78622701 0.5402 0.9204 NA NANA NA WCM218_Z3_1 X 79277892 154509348 −0.1042 −0.1265 NA NA NA NAWCM219 1 14896 249213458 0.0217 0.1472 1.1878 1.027 1 1 WCM219 10 225960135439016 0.016 0.0389 1.0874 0.9672 1 1 WCM219 11 193096 1346059060.0173 0.0646 2.1884 −0.0968 2 0 WCM219 12 148513 133810703 0.0072−0.1415 0.9663 0.8468 1 1 WCM219 13 19041994 115089411 0.0034 −0.22890.8731 0.8334 1 1 WCM219 14 19110183 107283266 0.0164 0.048 1.114 0.95371 1 WCM219 15 20083896 102516227 0.0346 0.3654 1.3897 1.1868 1 1 WCM21916 64400 90260461 0.0082 −0.1196 0.9802 0.8607 1 1 WCM219 17 13159581187855 0.0159 0.0368 1.0259 1.0259 1 1 WCM219 18 47581 78005279 0.0091−0.1005 1.0124 0.853 1 1 WCM219 19 105010 59093696 −0.0095 −0.56450.7549 0.5975 1 1 WCM219 2 41595 243037022 0.0059 −0.1711 0.8882 0.88821 1 WCM219 20 68340 62934592 0.0399 0.4459 1.464 1.2603 1 1 WCM219 219590311 48084170 0.0208 0.1294 1.134 1.0536 1 1 WCM219 22 1615906851223730 0.0529 0.6295 1.6497 1.4443 2 1 WCM219 3 239459 1978966830.0105 −0.0712 1.0316 0.872 1 1 WCM219 4 53422 190878508 −0.0048 −0.4330.7605 0.721 1 1 WCM219 5 90714 180687808 −0.0018 −0.3541 0.7824 0.78241 1 WCM219 6 203583 170892883 −0.0087 −0.5386 0.7081 0.6688 1 1 WCM219 7193245 158937357 0.0054 −0.1836 1.8149 −0.0539 2 0 WCM219 8 163470146279424 0.0035 −0.2253 0.8753 0.8356 1 1 WCM219 9 116800 1411075140.0329 0.3384 1.3657 1.163 1 1 WCM219 X 2700084 154507335 −0.1425 NA NANA NA NA WCM223 1 14930 249213964 0.02 0.1589 1.1165 1.1165 1 1 WCM22310 225995 135439051 0.0223 0.1761 1.1298 1.1298 1 1 WCM223 11 18017063884918 0.0103 0.0834 1.0763 1.0427 1 1 WCM223 11 63885182 65827316−0.177 −4.7292 0.0377 0.0377 0 0 WCM223 11 65828033 134605954 0.00640.0522 1.0368 1.0368 1 1 WCM223 12 148485 133810788 −0.0043 −0.03650.975 0.975 1 1 WCM223 13 19041937 115089411 −0.0032 −0.0272 0.98130.9813 1 1 WCM223 14 19110297 107283269 0.0017 0.0144 1.01 1.01 1 1WCM223 15 20083896 102506269 0.0285 0.2221 1.1664 1.1664 1 1 WCM223 1674427 90168828 −0.014 −0.1213 0.9194 0.9194 1 1 WCM223 17 13159581052545 0.0059 0.0482 1.034 1.034 1 1 WCM223 18 47610 78005146 0.00340.0283 1.0198 1.0198 1 1 WCM223 19 104935 59093696 −0.0465 −0.44270.7357 0.7357 1 1 WCM223 2 41670 243037103 0.0025 0.0205 1.0143 1.0143 11 WCM223 20 68299 62934541 0.0118 0.0956 1.0685 1.0685 1 1 WCM223 219590292 48084211 0.002 0.0165 1.0115 1.0115 1 1 WCM223 22 1615907951219089 0.0275 0.2144 1.1602 1.1602 1 1 WCM223 3 239443 1978968000.0021 0.0174 1.0121 1.0121 1 1 WCM223 4 53375 190904482 −0.0031 −0.02590.9822 0.9822 1 1 WCM223 5 90680 180687808  6.00E−04 0.0054 1.00371.0037 1 1 WCM223 6 203515 170892869 0.0026 0.0215 1.015 1.015 1 1WCM223 7 193189 158937018 −0.0069 −0.0582 0.9605 0.9605 1 1 WCM223 8163461 146279489 −0.0075 −0.0639 0.9567 0.9567 1 1 WCM223 9 116867141107535 0.0148 0.1193 1.0862 1.0862 1 1 WCM223 X 2700087 154493598−0.0839 −0.9181 NA NA NA NA WCM223_Z2_1 1 69594 17958926 −0.0067 −0.0820.9576 0.932 1 1 WCM223_Z2_1 1 17961381 32560384 −0.1532 −0.2487 0.94590.7374 1 1 WCM223_Z2_1 1 32566212 249212550 0.0218 −0.0498 1.0347 0.89741 1 WCM223_Z2_1 10 225952 135440086 −0.106 −0.1948 1.0163 0.7311 1 1WCM223_Z2_1 11 193146 36657634 0.0482 −0.0201 1.0794 0.893 1 1WCM223_Z2_1 11 36669589 49080617 −0.8175 −1.0426 0.871 0.0999 1 0WCM223_Z2_1 11 49089189 104034549 0.0349 −0.035 0.987 0.965 1 1WCM223_Z2_1 11 104757520 106856850 −0.8449 −1.0771 NA NA NA NAWCM223_Z2_1 11 107197755 134856574 0.039 −0.0304 0.9869 0.9714 1 1WCM223_Z2_1 12 148811 124497463 0.0607 −0.006 1.0877 0.9041 1 1WCM223_Z2_1 12 124796378 125396273 −0.7154 −0.9156 NA NA NA NAWCM223_Z2_1 12 125397541 133810842 0.0382 −0.0313 1.005 0.9521 1 1WCM223_Z2_1 13 19600515 40175311 0.0565 −0.0106 1.0049 0.9804 1 1WCM223_Z2_1 13 40229957 58299417 −0.7354 −0.9403 1.0465 −0.0043 1 0WCM223_Z2_1 13 60240829 72440384 0.1679 0.114 NA NA NA NA WCM223_Z2_1 1372440887 77663054 −0.7502 −0.9586 0.9964 0.0328 1 0 WCM223_Z2_1 1377664299 100295350 0.0768 0.0121 1.0265 0.9903 1 1 WCM223_Z2_1 13100511293 108518188 −0.8426 −1.0741 0.9771 −0.0272 1 0 WCM223_Z2_1 13108518377 115089411 0.1001 0.0383 1.058 0.9958 1 1 WCM223_Z2_1 1420201899 107283184 0.0662  2.00E−04 1.0642 0.9361 1 1 WCM223_Z2_1 1520170028 102389740 0.0731 0.008 1.1004 0.9107 1 1 WCM223_Z2_1 16 9746249672433 0.0585 −0.0084 1.0098 0.9785 1 1 WCM223_Z2_1 16 4967276184108282 −0.7631 −0.9747 1.0186 −9.00E−04  1 0 WCM223_Z2_1 16 8411540690233626 0.1144 0.0543 1.1092 0.9675 1 1 WCM223_Z2_1 17 131595 810834570.0574 −0.0096 1.0056 0.9811 1 1 WCM223_Z2_1 18 48235 78005160 0.0645−0.0017 1.01 0.9876 1 1 WCM223_Z2_1 19 281507 59083929 −0.1357 −0.22870.9746 0.7323 1 1 WCM223_Z2_1 2 41613 43015719 0.0676 0.0018 1.05970.9427 1 1 WCM223_Z2_1 2 43019611 45235872 −0.579 −0.7492 1.0613 0.12861 0 WCM223_Z2_1 2 45236148 114715029 0.079 0.0146 1.0249 0.9954 1 1WCM223_Z2_1 2 115200395 138425397 −0.7513 −0.96 1.0484 −0.0203 1 0WCM223_Z2_1 2 138434157 148653997 0.0289 −0.0418 1.0284 0.9145 1 1WCM223_Z2_1 2 148657382 162251649 −0.695 −0.8905 1.0798 −9.00E−04  1 0WCM223_Z2_1 2 162265348 163302810 0.1683 0.1145 NA NA NA NA WCM223_Z2_12 163360961 183291329 −0.7523 −0.9613 1.0316 −0.0044 1 0 WCM223_Z2_1 2183387026 242946597 0.0664  4.00E−04 1.0565 0.9441 1 1 WCM223_Z2_1 2068373 62904835 0.0657 −4.00E−04 1.0941 0.9054 1 1 WCM223_Z2_1 21 982623548084282 0.0691 0.0035 1.0159 0.9889 1 1 WCM223_Z2_1 22 1628744351215137 0.0427 −0.0262 0.9974 0.9665 1 1 WCM223_Z2_1 3 239459 758324830.0643 −0.0019 1.0548 0.9426 1 1 WCM223_Z2_1 3 75986643 89391019 −0.7013−0.8982 NA NA NA NA WCM223_Z2_1 3 89391220 98309560 0.0629 −0.00351.0368 0.9583 1 1 WCM223_Z2_1 3 98309871 99683234 −0.6816 −0.874 NA NANA NA WCM223_Z2_1 3 99860401 118649049 0.082 0.018 1.0262 0.9989 1 1WCM223_Z2_1 3 118753396 120347345 −0.7028 −0.9001 1.0753 −0.0036 1 0WCM223_Z2_1 3 120352070 197896714 0.0482 −0.02 1.0007 0.9718 1 1WCM223_Z2_1 4 59327 190426502 0.0698 0.0043 1.0154 0.9906 1 1WCM223_Z2_1 5 140632 71495575 0.0761 0.0113 1.0215 0.9943 1 1WCM223_Z2_1 5 71496025 77524025 −0.7166 −0.917 1.0685 −0.0093 1 0WCM223_Z2_1 5 77536725 96315010 0.0918 0.029 1.0592 0.9814 1 1WCM223_Z2_1 5 96315192 101816132 −0.5911 −0.7638 NA NA NA NA WCM223_Z2_15 101834232 102611706 −2.3815 −3.6014 NA NA NA NA WCM223_Z2_1 5102611934 111312435 −0.8076 −1.0302 NA NA NA NA WCM223_Z2_1 5 111479564112178437 −2.4942 −3.9015 NA NA NA NA WCM223_Z2_1 5 112178759 112927754−0.7545 −0.9639 1.0274 −0.0021 1 0 WCM223_Z2_1 5 113698579 1240805420.1064 0.0453 1.0654 0.9984 1 1 WCM223_Z2_1 5 125696083 126993282−0.8064 −1.0287 NA NA NA NA WCM223_Z2_1 5 127419805 151784397 0.0603−0.0064 1.0247 0.9665 1 1 WCM223_Z2_1 5 151784521 156887344 −0.807−1.0295 0.9985 −0.0187 1 0 WCM223_Z2_1 5 156887583 167489211 0.0651−0.001 1.0756 0.9229 1 1 WCM223_Z2_1 5 167517764 169186755 −0.8338−1.0631 0.9941 −0.0369 1 0 WCM223_Z2_1 5 169188534 180687804 0.0593−0.0075 1.0216 0.9679 1 1 WCM223_Z2_1 6 203545 70733547 0.0262 −0.04471.0318 0.9072 1 1 WCM223_Z2_1 6 70744183 100838345 −0.7825 −0.99881.0215 −0.0206 1 0 WCM223_Z2_1 6 100838569 170893450 0.0319 −0.03840.9924 0.9551 1 1 WCM223_Z2_1 7 193451 158937416 0.0558 −0.0115 1.08360.9006 1 1 WCM223_Z2_1 8 190900 146279527 0.0619 −0.0046 1.008 0.9856 11 WCM223_Z2_1 9 17066 141111414 0.0508 −0.017 0.9972 0.9794 1 1WCM223_Z2_1 X 2700146 154509348 −0.0286 −0.1068 NA NA NA NA WCM223_Z4_11 69569 46685865 0.0408 0.036 1.0339 1.0165 1 1 WCM223_Z4_1 1 4671424249711536 0.4907 0.5097 1.9459 0.9016 2 1 WCM223_Z4_1 1 50162959174769612 −0.0572 −0.0684 0.9537 0.9537 1 1 WCM223_Z4_1 1 174781061249212557 0.058 0.0542 1.0383 1.0383 1 1 WCM223_Z4_1 10 225960 1354401080.0502 0.046 1.0324 1.0324 1 1 WCM223_Z4_1 11 193146 36657651 0.05570.0518 1.0464 1.0266 1 1 WCM223_Z4_1 11 36669604 48511269 −0.8631−0.9484 0.9775 0.059 1 0 WCM223_Z4_1 11 48997230 104034537 0.0496 0.04531.0319 1.0319 1 1 WCM223_Z4_1 11 104757470 106856849 −0.9242 −1.01730.9855 0.0026 1 0 WCM223_Z4_1 11 107197725 134856597 0.029 0.0234 1.01631.0163 1 1 WCM223_Z4_1 12 148644 124497381 0.0566 0.0527 1.0416 1.0328 11 WCM223_Z4_1 12 124497466 125396262 −0.7638 −0.8373 NA NA NA NAWCM223_Z4_1 12 125397541 133810788 0.0424 0.0377 1.0461 1.0068 1 1WCM223_Z4_1 13 19600371 40175311 0.0686 0.0654 1.0586 1.0342 1 1WCM223_Z4_1 13 40229957 58299425 −0.8994 −0.9893 1.0111 −0.0037 1 0WCM223_Z4_1 13 60240829 72440887 −0.1664 −0.1852 NA NA NA NA WCM223_Z4_113 73284470 77661658 −0.942 −1.0373 1.0124 −0.0379 1 0 WCM223_Z4_1 1377663003 100295349 −0.0533 −0.0642 0.9697 0.9432 1 1 WCM223_Z4_1 13100511205 108183525 −0.9593 −1.0569 0.9407 0.0206 1 0 WCM223_Z4_1 13108518049 115089411 −0.0116 −0.0197 0.998 0.9749 1 1 WCM223_Z4_1 1419377733 107283183 −0.04 −0.0501 0.972 0.9597 1 1 WCM223_Z4_1 1520169982 102389740 −0.0439 −0.0542 0.9734 0.9529 1 1 WCM223_Z4_1 1697439 49672681 −0.036 −0.0458 0.9791 0.9584 1 1 WCM223_Z4_1 16 4976483784108301 −0.92 −1.0125 0.9931 −0.0017 1 0 WCM223_Z4_1 16 8411550290233642 −0.0184 −0.027 0.995 0.9679 1 1 WCM223_Z4_1 17 131595 81083561−0.0149 −0.0233 0.9882 0.9798 1 1 WCM223_Z4_1 18 48269 78005215 −0.0627−0.0743 0.962 0.9376 1 1 WCM223_Z4_1 19 281445 59083970 −0.1943 −0.21510.9919 0.731 1 1 WCM223_Z4_1 2 41609 114492232 −0.0478 −0.0583 0.96550.9553 1 1 WCM223_Z4_1 2 114493367 138727740 −0.9046 −0.9951 1.0095−0.0061 1 0 WCM223_Z4_1 2 138738916 147346315 −0.1442 −0.1614 0.90470.8836 1 1 WCM223_Z4_1 2 147596973 162251613 −0.958 −1.0555 0.9792−0.017 1 0 WCM223_Z4_1 2 162265398 163374493 −0.0113 −0.0195 NA NA NA NAWCM223_Z4_1 2 163393463 183291329 −0.9607 −1.0585 0.9626 −0.0024 1 0WCM223_Z4_1 2 183387026 242946597 −0.0524 −0.0632 0.9622 0.952 1 1WCM223_Z4_1 20 68397 62904890 −0.0143 −0.0227 0.9844 0.9844 1 1WCM223_Z4_1 21 9826235 35987113 −0.0729 −0.0851 0.9759 0.9095 1 1WCM223_Z4_1 21 36041973 42830468 −0.9395 −1.0346 0.964 0.0123 1 0WCM223_Z4_1 21 42838075 48084282 −0.0203 −0.0291 0.9978 0.9623 1 1WCM223_Z4_1 22 16287481 51215134 −0.0023 −0.0099 0.9932 0.9932 1 1WCM223_Z4_1 3 239472 75986730 −0.0338 −0.0434 0.9745 0.9662 1 1WCM223_Z4_1 3 77147269 89259670 −0.9195 −1.0119 NA NA NA NA WCM223_Z4_13 89390222 98312348 −0.0979 −0.1118 0.962 0.8888 1 1 WCM223_Z4_1 398451717 99683234 −0.9506 −1.047 NA NA NA NA WCM223_Z4_1 3 99860401118753415 −0.0602 −0.0716 0.9739 0.9292 1 1 WCM223_Z4_1 3 118865097120347292 −0.8865 −0.9747 0.9985 0.0192 1 0 WCM223_Z4_1 3 120352064197896720 −0.0411 −0.0513 0.9744 0.9558 1 1 WCM223_Z4_1 4 59334190426471 0.0382 0.0332 1.0309 1.0156 1 1 WCM223_Z4_1 5 140666 714995320.0461 0.0415 1.0401 1.0183 1 1 WCM223_Z4_1 5 71500934 77524037 −0.8401−0.9226 1.0764 −0.0212 1 0 WCM223_Z4_1 5 77536725 96253296 0.0191 0.01291.0347 0.9832 1 1 WCM223_Z4_1 5 96315004 101834442 −0.7876 −0.8639 NA NANA NA WCM223_Z4_1 5 102237108 102612076 −3.1008 −4.0691 NA NA NA NAWCM223_Z4_1 5 102612215 111311009 −0.8139 −0.8933 NA NA NA NAWCM223_Z4_1 5 111312435 112178381 −3.0827 −4.0319 NA NA NA NAWCM223_Z4_1 5 112178770 112927786 −0.8318 −0.9133 1.0461 0.0159 1 0WCM223_Z4_1 5 113698705 124080262 0.1019 0.1008 1.1121 1.0326 1 1WCM223_Z4_1 5 124080309 126993282 −0.8141 −0.8935 NA NA NA NAWCM223_Z4_1 5 127419802 151784655 0.0472 0.0427 1.0355 1.0246 1 1WCM223_Z4_1 5 152869386 156887202 −0.8435 −0.9264 1.079 −0.0267 1 0WCM223_Z4_1 5 156887583 167489255 0.0391 0.0341 1.0587 0.9891 1 1WCM223_Z4_1 5 167517646 169188527 −0.8062 −0.8847 1.1234 −0.0402 1 0WCM223_Z4_1 5 169230068 180687808 0.0332 0.0279 1.0293 1.0098 1 1WCM223_Z4_1 6 203542 70733547 0.0539 0.0498 1.0352 1.0352 1 1WCM223_Z4_1 6 70744192 100403928 −0.8417 −0.9244 1.0574 −0.0036 1 0WCM223_Z4_1 6 100838312 170893411 0.0462 0.0416 1.0325 1.026 1 1WCM223_Z4_1 7 193245 158937416 0.0477 0.0433 1.0359 1.025 1 1WCM223_Z4_1 8 190906 21608453 0.0752 0.0725 1.0694 1.0337 1 1WCM223_Z4_1 8 21766846 30335312 −0.8669 −0.9526 1.0339 −6.00E−04  1 0WCM223_Z4_1 8 30336893 146279498 0.0716 0.0686 1.0576 1.0398 1 1WCM223_Z4_1 9 17055 141111414 0.0502 0.0459 1.0323 1.0323 1 1WCM223_Z4_1 X 2700139 154509348 0.0209 0.0148 NA NA NA NA WCM243 1 149306221386 0.0113 0.2532 1.1918 1.1918 1 1 WCM243 1 6226299 109897022−0.1503 −0.6402 0.6416 0.6416 1 1 WCM243 1 109897983 214781971 0.14930.7763 1.7127 1.7127 2 2 WCM243 1 214787266 235902124 −0.0604 −0.08921.2266 0.6535 1 1 WCM243 1 235904395 249214018 0.1588 0.808 1.75081.7508 2 2 WCM243 10 226083 135438994 −0.037 0.0296 1.0207 1.0207 1 1WCM243 11 193096 9769562 0.012 0.2561 1.1942 1.1942 1 1 WCM243 119770622 93803559 0.0903 0.5696 1.4842 1.4842 1 1 WCM243 11 93806210134320516 −0.0792 −0.191 0.876 0.876 1 1 WCM243 12 148452 69145785−0.1835 −0.8994 0.5361 0.5361 1 1 WCM243 12 69152951 133345574 0.00940.2449 1.185 1.185 1 1 WCM243 12 133347659 133810794 −0.2109 −1.15010.4506 0.4506 0 0 WCM243 13 19041992 115089411 0.0952 0.5875 1.50271.5027 2 2 WCM243 14 19110343 107283169 0.0213 0.296 1.2277 1.2277 1 1WCM243 15 20083896 63986772 0.1258 0.6965 1.6205 1.6205 2 2 WCM243 1563987016 102304817 −0.1427 −0.5865 0.666 0.666 1 1 WCM243 15 102311872102506258 0.1378 0.7378 NA NA NA NA WCM243 16 74369 48218471 −0.053−0.0507 0.9655 0.9655 1 1 WCM243 16 48221117 81185425 −0.1975 −1.02220.5373 0.4474 1 0 WCM243 16 81187685 90260461 −0.161 −0.7192 0.60740.6074 1 1 WCM243 17 131595 8508157 −0.0552 −0.0622 1.9741 −0.0586 2 0WCM243 17 8526369 39791573 0.04 0.3741 2.5406 0.0515 3 0 WCM243 1739845329 81187853 −0.1442 −0.5968 0.6612 0.6612 1 1 WCM243 18 4769278005146 0.0282 0.3253 1.2529 1.2529 1 1 WCM243 19 105080 1277169−0.0567 −0.0698 1.2797 0.6259 1 1 WCM243 19 1278977 31767287 0.06850.4871 1.4017 1.4017 1 1 WCM243 19 31767676 43023375 −0.1845 −0.90780.533 0.533 1 1 WCM243 19 43025541 43920730 0.4938 1.702 3.7758 2.7313 43 WCM243 19 43922159 59093645 −0.1793 −0.8645 0.5492 0.5492 1 1 WCM243 241647 243037116 −0.1635 −0.7389 0.5992 0.5992 1 1 WCM243 20 6836342574625 −0.0024 0.1925 1.1427 1.1427 1 1 WCM243 20 42597482 629345720.3195 1.28 2.4284 2.4284 2 2 WCM243 21 9590301 48084253 −0.0988 −0.30370.8102 0.8102 1 1 WCM243 22 16159014 51216306 −0.0452 −0.0112 0.99220.9922 1 1 WCM243 3 239531 197894690 −0.0526 −0.0488 0.9667 0.9667 1 1WCM243 4 53364 190873327 −0.0929 −0.2686 0.8301 0.8301 1 1 WCM243 590647 52285275 −0.0219 0.1023 1.0735 1.0735 1 1 WCM243 5 52322635148377838 −0.19 −0.9557 0.5156 0.5156 1 1 WCM243 5 148381846 1806878300.0611 0.4584 1.374 1.374 1 1 WCM243 6 203475 170892848 −0.0671 −0.12460.9172 0.9172 1 1 WCM243 7 193253 158937018 0.1378 0.7379 1.7131 1.62242 2 WCM243 8 166429 146279383 0.0278 0.3234 1.2513 1.2513 1 1 WCM243 9116867 105768000 −0.1719 −0.8043 0.5727 0.5727 1 1 WCM243 9 106857798141013089 −0.0243 0.0909 1.5412 0.5889 2 1 WCM243 9 141014652 141107513−0.0408 0.0112 NA NA NA NA WCM243 X 2700151 154493340 −0.2346 −1.4029 NANA NA NA WCM243_X1_1 1 69603 878432 0.0032 0.6782 NA NA NA NAWCM243_X1_1 1 878700 15863120 −0.0419 0.6161 2.0352 1.0303 2 1WCM243_X1_1 1 15870980 50460823 −0.4439 0.0245 1.0589 0.9754 1 1WCM243_X1_1 1 50460995 53925184 −0.9393 −0.8603 0.9275 0.1741 1 0WCM243_X1_1 1 53925585 109940443 −0.4287 0.0485 1.1639 0.9045 1 1WCM243_X1_1 1 109944699 120611999 0.2419 0.9954 3.0286 0.9587 3 1WCM243_X1_1 1 143767833 214822081 0.4998 1.3212 2.9525 2.0451 3 2WCM243_X1_1 1 214825220 236175291 −0.0485 0.607 3.0405 0.0057 3 0WCM243_X1_1 1 236176739 249212366 0.5036 1.3259 2.9463 2.0676 3 2WCM243_X1_1 10 225980 135440086 −0.0515 0.6029 1.9926 1.0449 2 1WCM243_X1_1 11 193146 34511577 0.2751 1.0382 2.0854 2.022 2 2WCM243_X1_1 11 34515066 36596676 0.4591 1.2708 3.0791 1.7469 3 2WCM243_X1_1 11 36597061 48285558 0.5189 1.3448 3.9597 1.1202 4 1WCM243_X1_1 11 48285705 77594926 0.491 1.3104 3.0262 1.9342 3 2WCM243_X1_1 11 77595863 93400796 0.308 1.0805 2.212 2.0175 2 2WCM243_X1_1 11 93402856 134856523 −0.0573 0.5948 1.9906 1.0299 2 1WCM243_X1_1 12 148673 69265683 −0.4329 0.0419 1.0489 1.0101 1 1WCM243_X1_1 12 69279662 112893752 −0.0542 0.599 2.0885 0.9409 2 1WCM243_X1_1 12 112910815 133810926 0.2475 1.0026 2.0037 2.0037 2 2WCM243_X1_1 13 19600365 29291983 0.5171 1.3427 4.1198 0.9526 4 1WCM243_X1_1 13 29598959 54886136 0.251 1.0072 3.0021 1.0178 3 1WCM243_X1_1 13 55748673 97639984 0.487 1.3054 4.0775 0.8657 4 1WCM243_X1_1 13 97928639 115089411 0.1941 0.9333 2.7786 1.0407 3 1WCM243_X1_1 14 19377727 20770020 −0.03 0.6326 2.198 0.9026 2 1WCM243_X1_1 14 20774081 21359923 0.2851 1.0511 3.0614 1.0828 3 1WCM243_X1_1 14 21360144 38218418 −0.04 0.6188 2.0259 1.0452 2 1WCM243_X1_1 14 38220376 107283085 0.2486 1.004 2.0238 1.9874 2 2WCM243_X1_1 15 20170011 22382897 −0.0025 0.6704 2.5959 0.5871 3 1WCM243_X1_1 15 22383189 42680058 0.2343 0.9856 2.9301 1.0302 3 1WCM243_X1_1 15 42681250 43132576 −0.4096 0.0782 NA NA NA NA WCM243_X1_115 43164810 43483717 0.31 1.0829 NA NA NA NA WCM243_X1_1 15 4348498152622650 0.7091 1.5756 5.0143 0.9469 5 1 WCM243_X1_1 15 5262871963970465 0.2633 1.023 2.9359 1.1285 3 1 WCM243_X1_1 15 63972297102514214 −0.4405 0.03 1.132 0.91 1 1 WCM243_X1_1 16 67604 46508225−0.0424 0.6154 2.0194 1.0446 2 1 WCM243_X1_1 16 46509904 48212572 0.26391.0238 NA NA NA NA WCM243_X1_1 16 48218460 90233603 −0.4357 0.0375 2.030.0226 2 0 WCM243_X1_1 17 131595 4356483 0.2092 0.9529 3.8962 −0.0247 40 WCM243_X1_1 17 4381921 4925943 −0.0436 0.6137 3.0866 −0.0262 3 0WCM243_X1_1 17 4926882 7216124 0.1879 0.9251 3.8182 −0.0205 4 0WCM243_X1_1 17 7216586 7592579 −1.0079 −1.0057 1.0299 −0.0338 1 0WCM243_X1_1 17 7592957 17696270 −0.0515 0.6028 3.0223 0.015 3 0WCM243_X1_1 17 17696750 21191389 0.2324 0.9831 3.9639 −0.0104 4 0WCM243_X1_1 17 21194820 22023445 0.1154 0.8294 2.0985 1.4554 2 1WCM243_X1_1 17 25621441 40265724 0.2357 0.9874 3.9255 0.0398 4 0WCM243_X1_1 17 40266254 56060735 −0.0524 0.6016 3.0265 0.0083 3 0WCM243_X1_1 17 56082752 81083567 −0.4542 0.0082 1.9806 0.0308 2 0WCM243_X1_1 18 48190 78005164 0.2182 0.9647 1.9719 1.9313 2 2WCM243_X1_1 19 281503 32083868 0.2276 0.9769 2.8832 1.0534 3 1WCM243_X1_1 19 32843799 59083923 −0.462 −0.0041 1.1318 0.8625 1 1WCM243_X1_1 2 41612 44079913 −0.4181 0.0651 1.0723 1.02 1 1 WCM243_X1_12 44099168 47085320 −0.8972 −0.7746 NA NA NA NA WCM243_X1_1 2 47132711242946607 −0.4331 0.0415 1.0664 0.992 1 1 WCM243_X1_1 20 68397 26188912−0.0504 0.6043 2.0303 1.0102 2 1 WCM243_X1_1 20 29632632 39726959 0.25721.0152 2.1568 1.8855 2 2 WCM243_X1_1 20 39728812 42602040 −0.0191 0.6476NA NA NA NA WCM243_X1_1 20 42635393 62904861 0.8828 1.7812 4.9462 1.92795 2 WCM243_X1_1 21 9826225 39822803 −0.058 0.5938 1.9118 1.1067 2 1WCM243_X1_1 21 39947608 43133145 −0.4193 0.0632 2.073 0.0166 2 0WCM243_X1_1 21 43133829 44195395 0.0155 0.6949 2.0931 1.1445 2 1WCM243_X1_1 21 44270183 48056892 −0.4281 0.0495 2.0601 0.0097 2 0WCM243_X1_1 21 48063531 48084281 −0.1265 0.4977 NA NA NA NA WCM243_X1_122 16287478 21576160 0.2498 1.0057 2.0935 1.9223 2 2 WCM243_X1_1 2221799370 29759016 −0.0783 0.5656 2.0795 0.8805 2 1 WCM243_X1_1 2229815167 31795693 −0.4727 −0.0211 1.9292 0.0418 2 0 WCM243_X1_1 2231796610 51219138 −0.0739 0.5716 2.0212 0.9512 2 1 WCM243_X1_1 3 23952468055826 −0.0562 0.5963 2.0052 1.0186 2 1 WCM243_X1_1 3 6846653974351914 0.4053 1.2037 NA NA NA NA WCM243_X1_1 3 74384005 97311581−0.0816 0.5609 NA NA NA NA WCM243_X1_1 3 97329692 116163815 0.25571.0132 2.0732 1.9637 2 2 WCM243_X1_1 3 116569172 120976170 −0.03420.6268 2.1814 0.9068 2 1 WCM243_X1_1 3 120977904 125199137 −0.43820.0336 1.974 0.0732 2 0 WCM243_X1_1 3 125216198 197894713 −0.0477 0.60812.0015 1.047 2 1 WCM243_X1_1 4 59405 40440867 −0.4302 0.0462 1.06331.0018 1 1 WCM243_X1_1 4 40504083 49063839 −0.0353 0.6253 2.1623 0.92272 1 WCM243_X1_1 4 52709800 54880275 −0.9531 −0.8888 NA NA NA NAWCM243_X1_1 4 54915170 57976487 −0.4383 0.0334 1.1201 0.9268 1 1WCM243_X1_1 4 61788391 69434201 −0.9229 −0.8265 NA NA NA NA WCM243_X1_14 69696596 125591686 −0.0395 0.6195 2.0312 1.0415 2 1 WCM243_X1_1 4125591799 138453409 −0.4471 0.0195 NA NA NA NA WCM243_X1_1 4 139100419152498625 −0.0398 0.6191 3.1325 −0.0608 3 0 WCM243_X1_1 4 152499055156643299 −0.3277 0.2038 2.2352 0.0683 2 0 WCM243_X1_1 4 156651366156764911 −1.7778 −4.3452 NA NA NA NA WCM243_X1_1 4 157555881 159590915−0.3774 0.1281 NA NA NA NA WCM243_X1_1 4 159592912 178257420 −0.05720.595 2.874 0.1469 3 0 WCM243_X1_1 4 178260970 178911657 0.0321 0.7175NA NA NA NA WCM243_X1_1 4 183090470 186064618 −0.7729 −0.5354 1.37972.00E−04 1 0 WCM243_X1_1 4 186066098 190426570 −0.0689 0.5787 1.92011.0669 2 1 WCM243_X1_1 5 140532 52145311 −0.0417 0.6164 1.9338 1.1323 21 WCM243_X1_1 5 52157358 78938702 −0.4366 0.036 1.0446 1.0059 1 1WCM243_X1_1 5 78941013 79768623 −0.9167 −0.8138 NA NA NA NA WCM243_X1_15 79770520 83680163 −0.4066 0.083 1.1777 0.9406 1 1 WCM243_X1_1 585578660 112927811 −0.955 −0.8928 1.0531 0.024 1 0 WCM243_X1_1 5112929081 148045072 −0.4342 0.0399 1.0506 1.0054 1 1 WCM243_X1_1 5148206641 180687768 0.2452 0.9996 3.0006 0.9984 3 1 WCM243_X1_1 6 203546159420735 −0.0433 0.6142 2.0052 1.0563 2 1 WCM243_X1_1 6 159421004170893406 −0.4224 0.0583 2.0688 0.0136 2 0 WCM243_X1_1 7 193222 635299500.2434 0.9974 3.0118 0.981 3 1 WCM243_X1_1 7 63537737 100549579 0.48371.3014 4.0333 0.8959 4 1 WCM243_X1_1 7 100549873 100634157 0.5931 1.43563.4194 1.9905 3 2 WCM243_X1_1 7 100634374 158937185 0.4995 1.3209 3.97011.0265 4 1 WCM243_X1_1 8 190900 32621630 −0.0484 0.6072 2.0151 1.0315 21 WCM243_X1_1 8 33230211 146279483 0.2465 1.0014 2.0227 1.9812 2 2WCM243_X1_1 9 116836 12704701 −0.963 −0.9095 1.0452 0.0196 1 0WCM243_X1_1 9 12708079 105767269 −0.4227 0.0579 1.9984 0.0835 2 0WCM243_X1_1 9 105767545 141111414 −0.0546 0.5985 3.0356 −0.0073 3 0WCM243_X1_1 X 2707735 27999355 −0.4791 −0.0314 NA NA NA NA WCM243_X1_1 X28807508 57020905 0.2007 0.9419 NA NA NA NA WCM243_X1_1 X 5702124465486396 0.6779 1.5382 NA NA NA NA WCM243_X1_1 X 65817849 680604283.0388 4.1168 NA NA NA NA WCM243_X1_1 X 68381320 80001126 0.1948 0.9341NA NA NA NA WCM243_X1_1 X 80049168 154509348 −0.4666 −0.0113 NA NA NA NAWCM247 1 17483 249213973 −0.0369 −0.1679 0.8901 0.8901 1 1 WCM247 10226021 135477913 −0.0636 −0.9285 0.5254 0.5254 1 1 WCM247 11 193096134605849 0.0055 0.5699 1.4844 1.4844 1 1 WCM247 12 148474 133810710−0.0658 −1.0105 0.4964 0.4964 0 0 WCM247 13 19042005 115089411 −0.1043NA −0.0164 −0.0164 0 0 WCM247 14 19110245 22371472 −0.0242 0.0929 1.06651.0665 1 1 WCM247 14 22372638 22981823 0.5819 3.529 11.5437 11.5437 12 12  WCM247 14 22982965 107283270 −0.0212 0.1478 1.1079 1.1079 1 1 WCM24715 20083910 102506269 −8.00E−04 0.4794 1.3941 1.3941 1 1 WCM247 16 6442990168697 −0.0446 −0.3496 0.7848 0.7848 1 1 WCM247 17 131595 81187901−0.0997 −4.5411 0.043 0.043 0 0 WCM247 18 47609 78005240 −0.0302 −0.02380.9836 0.9836 1 1 WCM247 19 105041 59093696 −0.0175 0.2134 1.1594 1.15941 1 WCM247 2 41623 243052713 −0.0769 −1.5291 0.3465 0.3465 0 0 WCM247 2068319 62934592 −0.0247 0.0835 1.0596 1.0596 1 1 WCM247 21 959033448084177 −0.0557 −0.6578 0.6339 0.6339 1 1 WCM247 22 16159014 51216306−0.0521 −0.5524 0.6819 0.6819 1 1 WCM247 3 239495 197896740 −0.00670.3914 1.3116 1.3116 1 1 WCM247 4 53423 190878508 −0.0297 −0.0148 0.98980.9898 1 1 WCM247 5 90714 180687861 −0.0082 0.3683 1.2909 1.2909 1 1WCM247 6 203397 170892918 −0.0614 −0.8486 0.5553 0.5553 1 1 WCM247 7193245 330721 0.174 2.0076 NA NA NA NA WCM247 7 538249 27191872 −0.1025−7.1518 0.007 0.007 0 0 WCM247 7 27192556 158937074 0.0894 1.4387 2.71082.7108 3 3 WCM247 8 163474 146279480 0.0536 1.1233 2.1785 2.1785 2 2WCM247 9 14885 141071710 −0.022 0.1346 1.0978 1.0978 1 1 WCM247 X2700148 154493576 0.0177 0.7289 NA NA NA NA WCM247_Z9_1 1 721476 7886717−0.0382 −0.3994 1.0513 0.4651 1 0 WCM247_Z9_1 1 7887421 11172909 −0.4713−2.0315 0.3355 0.1537 0 0 WCM247_Z9_1 1 11174386 46088946 −0.0431−0.4122 1.0021 0.5008 1 1 WCM247_Z9_1 1 46089316 46120340 −0.2364−0.9887 NA NA NA NA WCM247_Z9_1 1 46120949 87597961 −0.4639 −1.98780.5101 −0.0059 1 0 WCM247_Z9_1 1 87598225 109479978 −0.2591 −1.06780.9614 −0.0072 1 0 WCM247_Z9_1 1 109482344 214781892 0.1314 0.00741.0386 0.9718 1 1 WCM247_Z9_1 1 214782135 243736289 −0.2586 −1.06590.9842 −0.0289 1 0 WCM247_Z9_1 1 243809291 249212354 0.167 0.0852 1.0861.0357 1 1 WCM247_Z9_1 10 225988 76928356 −0.2417 −1.0068 0.5166 0.47871 0 WCM247_Z9_1 10 76935848 135053292 −0.0487 −0.4271 1.0053 0.4823 1 0WCM247_Z9_1 10 135053476 135440108 −0.2645 −1.0871 NA NA NA NAWCM247_Z9_1 11 193112 65484441 0.1353 0.0161 1.0246 0.9978 1 1WCM247_Z9_1 11 65486119 134856536 0.2565 0.2713 1.2458 1.1681 1 1WCM247_Z9_1 12 148637 133810896 −0.0498 −0.4299 0.9859 0.4987 1 0WCM247_Z9_1 13 19600515 115089411 −0.2437 −1.0137 0.9762 0.0144 1 0WCM247_Z9_1 14 19377703 107283184 0.1302 0.0049 1.0034 1.0034 1 1WCM247_Z9_1 15 20170150 102506276 −0.0937 −0.549 1.1123 0.2547 1 0WCM247_Z9_1 16 66926 90233622 −0.0419 −0.409 1.0001 0.5062 1 1WCM247_Z9_1 17 131595 44117119 −0.2392 −0.9983 0.9933 0.0079 1 0WCM247_Z9_1 17 44128049 47656367 0.1394 0.0253 1.1543 0.8811 1 1WCM247_Z9_1 17 47656511 80136385 −0.2309 −0.9697 1.0287 −0.0075 1 0WCM247_Z9_1 17 80137041 81083567 0.1098 −0.0407 0.9919 0.9524 1 1WCM247_Z9_1 18 48220 22907639 0.1169 −0.0249 1.0116 0.9542 1 1WCM247_Z9_1 18 22930877 78005219 −0.0624 −0.4635 0.9083 0.5421 1 1WCM247_Z9_1 19 281483 42741075 0.1228 −0.0115 1.0142 0.9699 1 1WCM247_Z9_1 19 42744173 52468136 −0.2508 −1.0385 0.9859 −0.0122 1 0WCM247_Z9_1 19 52468520 59083968 0.1365 0.0187 1.0309 0.9952 1 1WCM247_Z9_1 2 41609 128015197 −0.2411 −1.0049 1.0076 −0.011 1 0WCM247_Z9_1 2 128016945 242946597 −0.0425 −0.4105 0.9992 0.5055 1 1WCM247_Z9_1 20 68351 1895842 −0.443 −1.8697 0.4606 0.0866 0 0WCM247_Z9_1 20 1896055 25397817 −0.0582 −0.4522 0.7681 0.6938 1 1WCM247_Z9_1 20 25398790 62904845 0.097 −0.0699 1.4377 0.4677 1 0WCM247_Z9_1 21 9907304 48084210 −0.0517 −0.4348 0.9949 0.4847 1 0WCM247_Z9_1 22 17060362 51219138 −0.2405 −1.0026 1.0568 −0.0586 1 0WCM247_Z9_1 3 239431 197894726 0.1189 −0.0202 0.9994 0.9729 1 1WCM247_Z9_1 4 59385 190426459 −0.0384 −0.3999 1.0034 0.5124 1 1WCM247_Z9_1 5 140480 107559900 0.1206 −0.0164 1.0152 0.9622 1 1WCM247_Z9_1 5 107684154 112222787 −0.244 −1.0149 NA NA NA NA WCM247_Z9_15 112227443 180687766 0.1238 −0.0093 1.0202 0.967 1 1 WCM247_Z9_1 6203577 170893409 −0.0461 −0.42 0.9937 0.5012 1 1 WCM247_Z9_1 7 19320524331286 −0.2441 −1.0149 1.0203 −0.0306 1 0 WCM247_Z9_1 7 2466332577584192 0.3003 0.3582 2.5589 0.0048 3 0 WCM247_Z9_1 7 77648671157208739 0.2901 0.3383 2.0127 0.5158 2 1 WCM247_Z9_1 7 157234015158937161 0.3558 0.4647 NA NA NA NA WCM247_Z9_1 8 190907 81605336 0.12910.0025 1.024 0.9795 1 1 WCM247_Z9_1 8 81733727 146279480 0.502 0.72912.2249 1.0903 2 1 WCM247_Z9_1 9 17110 20764960 −0.0184 −0.3482 1.56460.0065 2 0 WCM247_Z9_1 9 20770103 23693476 −0.6799 −4.4062 NA NA NA NAWCM247_Z9_1 9 23701514 141111414 −0.0297 −0.3773 1.4851 0.0547 1 0WCM247_Z9_1 X 2700140 154509348 0.0827 −0.1026 NA NA NA NA WCM252 114930 2408066 0.0597 0.0631 1.0462 1.0433 1 1 WCM252 1 2409892 11097930−0.5608 −0.8795 0.9874 0.0997 1 0 WCM252 1 11102891 183881247 0.03650.0312 1.0219 1.0219 1 1 WCM252 1 183885666 200012867 −0.6089 −0.96290.9496 0.0765 1 0 WCM252 1 200014657 249213961 0.0322 0.0252 1.01761.0176 1 1 WCM252 10 226021 135438935 0.0111 −0.0041 0.9972 0.9972 1 1WCM252 11 193045 70387547 0.0214 0.0103 1.0072 1.0072 1 1 WCM252 1170449957 81601884 −0.5284 −0.8243 1.0197 0.1099 1 0 WCM252 11 82444623103175488 −0.0097 −0.033 0.9774 0.9774 1 1 WCM252 11 103178529 110001824−0.5513 −0.8632 0.9984 0.1011 1 0 WCM252 11 110007492 132307150 0.04520.0431 1.0303 1.0303 1 1 WCM252 11 132399108 134184202 −0.5429 −0.84881.0066 0.104 1 0 WCM252 11 134188671 134605916 0.0839 0.0962 NA NA NA NAWCM252 12 148430 111319152 0.417 0.5337 1.8039 1.0913 2 1 WCM252 12111321916 133683261 −0.0238 −0.0528 1.8381 0.0901 2 0 WCM252 12133697006 133810703 0.5676 0.7222 2.0268 1.2726 2 1 WCM252 13 1904200443155462 0.0026 −0.0159 0.9891 0.9891 1 1 WCM252 13 43175059 115089411−0.575 −0.9039 0.9389 0.13 1 0 WCM252 14 19110187 107283270 0.01820.0058 1.004 1.004 1 1 WCM252 15 20083896 102516227 0.0353 0.0295 1.02071.0207 1 1 WCM252 16 67591 90168693 −0.0034 −0.0243 0.9833 0.9833 1 1WCM252 17 131595 3716289 −0.018 −0.0446 0.9696 0.9696 1 1 WCM252 173716581 16614960 −0.5885 −0.9273 1.0061 0.0456 1 0 WCM252 17 1662349756357410 0.0136 −5.00E−04 0.9996 0.9996 1 1 WCM252 17 56357750 56604390−0.4643 −0.7176 1.0797 0.1365 1 0 WCM252 17 56604562 81187930 0.01730.0045 1.0032 1.0032 1 1 WCM252 18 47808 8406478 0.0148 0.0011 1.00081.0008 1 1 WCM252 18 8609854 10871272 −0.6316 −1.0031 0.9162 0.0817 1 0WCM252 18 10871415 11874986 −0.2733 −0.4165 NA NA NA NA WCM252 1811876613 74968072 0.0167 0.0038 1.0026 1.0026 1 1 WCM252 18 7498070778005123 −0.4993 −0.7755 1.1009 0.0675 1 0 WCM252 19 105041 4675262−0.5641 −0.8851 1.0122 0.0707 1 0 WCM252 19 4676683 24345254 0.02410.014 1.0097 1.0097 1 1 WCM252 19 29213655 31769738 2.1061 2.468 NA NANA NA WCM252 19 31770009 33701820 −0.5519 −0.8641 0.9632 0.1356 1 0WCM252 19 33702121 34513619 2.1489 2.5138 NA NA NA NA WCM252 19 3458353038055958 −0.5754 −0.9046 0.969 0.0994 1 0 WCM252 19 38056225 383979092.1984 2.5666 10.3749 1.4735 10  1 WCM252 19 38572055 39384115 −0.5244−0.8176 1.0188 0.116 1 0 WCM252 19 39384471 41399799 2.4183 2.799812.897 1.0301 13  1 WCM252 19 41404212 48973910 −0.5396 −0.8433 1.02570.089 1 0 WCM252 19 48976609 59093696 0.0087 −0.0073 0.9949 0.9949 1 1WCM252 2 41614 61025160 −0.0065 −0.0285 0.9804 0.9804 1 1 WCM252 261025409 62739000 −0.6492 −1.0345 NA NA NA NA WCM252 2 62901154127821611 −0.0019 −0.0221 0.9848 0.9848 1 1 WCM252 2 127825802 128583801−0.5502 −0.8613 1.0549 0.046 1 0 WCM252 2 128587255 128947505 0.04530.0433 1.0305 1.0305 1 1 WCM252 2 129025896 131672145 −0.5855 −0.9221 NANA NA NA WCM252 2 131672309 179843346 0.0075 −0.009 0.9938 0.9938 1 1WCM252 2 179912073 193059229 −0.5673 −0.8906 1.0082 0.0706 1 0 WCM252 2193059496 219960128 0.0364 0.031 1.0217 1.0217 1 1 WCM252 2 219976528229035272 −0.5943 −0.9373 0.9231 0.1213 1 0 WCM252 2 229035294 2334390240.0461 0.0444 1.0312 1.0312 1 1 WCM252 2 233445900 238233373 −0.5092−0.7919 1.0395 0.1156 1 0 WCM252 2 238234260 243037022 0.0235 0.01311.0091 1.0091 1 1 WCM252 20 68446 62934592 0.0079 −0.0085 0.9941 0.99411 1 WCM252 21 9590292 39891572 −0.0324 −0.0648 0.956 0.956 1 1 WCM252 2139903359 42866713 −0.6276 −0.9959 0.8994 0.1035 1 0 WCM252 21 4287004948084142 0.0332 0.0266 1.0186 1.0186 1 1 WCM252 22 16159043 512237300.0107 −0.0047 0.9968 0.9968 1 1 WCM252 3 239524 44884660 0.026 0.01661.0116 1.0116 1 1 WCM252 3 44889548 90306304 −0.5739 −0.9019 0.99440.0759 1 0 WCM252 3 93593059 176769541 0.4419 0.5651 1.9466 1.0124 2 1WCM252 3 176771755 184429374 −0.0127 −0.0372 0.9746 0.9746 1 1 WCM252 3184542422 197896678 0.4523 0.5783 1.9843 1.0019 2 1 WCM252 4 533442097555 −0.033 −0.0657 0.9555 0.9555 1 1 WCM252 4 2129996 5969113 −0.432−0.6651 1.0486 0.2126 1 0 WCM252 4 5975428 190903980 −0.0016 −0.02170.985 0.985 1 1 WCM252 5 90750 45695959 0.0088 −0.0072 0.995 0.995 1 1WCM252 5 49694840 68541847 −0.5939 −0.9367 0.9771 0.0677 1 0 WCM252 568546612 118729017 −0.0013 −0.0213 0.9853 0.9853 1 1 WCM252 5 118792001132270597 −0.5725 −0.8996 0.9661 0.1059 1 0 WCM252 5 132272804 153374509 1.00E−04 −0.0194 0.9866 0.9866 1 1 WCM252 5 153377398 154346445 −0.5166−0.8045 NA NA NA NA WCM252 5 154393462 180687821 0.0291 0.0209 1.01461.0146 1 1 WCM252 6 203428 24353742 −0.0161 −0.042 0.9713 0.9713 1 1WCM252 6 24357648 26225341 −0.6319 −1.0036 0.9559 0.0416 1 0 WCM252 626225743 165809769 0.0182 0.0059 1.0041 1.0041 1 1 WCM252 6 165826966170892855 −0.6232 −0.9881 0.8971 0.1112 1 0 WCM252 7 193205 1474342−0.0905 −0.1473 0.9029 0.9029 1 1 WCM252 7 1474799 4218082 −0.4688−0.7251 1.078 0.1319 1 0 WCM252 7 4226333 7677510 −0.0181 −0.0448 0.96940.9694 1 1 WCM252 7 7678680 16505341 −0.6059 −0.9577 0.9604 0.0693 1 0WCM252 7 16566645 18166885 −1.6706 −4.5338 NA NA NA NA WCM252 7 1833006820706356 −0.6114 −0.9673 0.9382 0.0847 1 0 WCM252 7 20721116 538792900.0265 0.0173 1.0121 1.0121 1 1 WCM252 7 53879540 62708584 −0.6485−1.0334 0.9317 0.0454 1 0 WCM252 7 62752657 107303886 0.0089 −0.00710.9978 0.9923 1 1 WCM252 7 107312607 108524593 −0.5895 −0.929 NA NA NANA WCM252 7 109599655 154989982 0.0745 0.0834 1.0595 1.0595 1 1 WCM252 7155014996 158937161 −0.1936 −0.2971 1.1061 0.5216 1 1 WCM252 8 16348623160868 −0.0298 −0.0612 0.9584 0.9584 1 1 WCM252 8 23167191 28205909−0.5517 −0.8639 0.9914 0.1075 1 0 WCM252 8 28206254 48068897 0.0027−0.0157 0.9892 0.9892 1 1 WCM252 8 48069064 59361259 −0.6043 −0.95490.9683 0.0635 1 0 WCM252 8 59363647 60032851 −1.5944 −3.9082 0.1345−0.0013 0 0 WCM252 8 60882984 70476343 −0.5857 −0.9225 0.94 0.1152 1 0WCM252 8 70488148 146279431 0.0282 0.0197 1.0138 1.0138 1 1 WCM252 915902 33750592 −0.571 −0.8969 0.9472 0.1268 1 0 WCM252 9 3378458135555392 0.041 0.0374 1.0729 0.9795 1 1 WCM252 9 35555914 87636359−0.5571 −0.873 0.963 0.129 1 0 WCM252 9 88162019 141107525 0.0419 0.03851.0271 1.0271 1 1 WCM252 X 2700122 154493601 0.0354 0.0297 NA NA NA NAWCM252_Z3_1 1 721450 2341812 0.0125 0.0266 1.0464 0.9909 1 1 WCM252_Z3_11 2342303 11103002 −0.667 −1.0085 0.9964 −0.0023 1 0 WCM252_Z3_1 111103514 183895406 −0.0177 −0.0146 1.0008 0.979 1 1 WCM252_Z3_1 1183899402 198828264 −0.6713 −1.0159 1.0572 −0.0682 1 0 WCM252_Z3_1 1199997036 249212344 −0.0168 −0.0135 1.0029 0.9784 1 1 WCM252_Z3_1 10226016 135440108 −0.0194 −0.0171 0.9882 0.9882 1 1 WCM252_Z3_1 11 19311370349036 −0.0067  4.00E−04 1.014 0.9866 1 1 WCM252_Z3_1 11 7050596281601788 −0.6665 −1.0076 1.0108 −0.016 1 0 WCM252_Z3_1 11 82443590103229027 −0.0406 −0.0462 0.9805 0.9564 1 1 WCM252_Z3_1 11 103270422109294927 −0.6928 −1.0538 NA NA NA NA WCM252_Z3_1 11 109964156 132398997−0.0291 −0.0304 0.9859 0.9724 1 1 WCM252_Z3_1 11 132527171 134229035−0.5989 −0.8917 NA NA NA NA WCM252_Z3_1 11 134234253 134856626 −0.04−0.0455 NA NA NA NA WCM252_Z3_1 12 148642 111311714 0.4136 0.5496 1.98990.9375 2 1 WCM252_Z3_1 12 111317723 133502284 −0.0079 −0.0012 2.0205−0.0221 2 0 WCM252_Z3_1 12 133670042 133810703 0.4627 0.6108 NA NA NA NAWCM252_Z3_1 13 19600364 42891786 −0.0297 −0.0311 1.007 0.9503 1 1WCM252_Z3_1 13 42893359 115089411 −0.661 −0.9979 1.0117 −0.0103 1 0WCM252_Z3_1 14 19377727 107283063 −0.0103 −0.0045 1.0023 0.9914 1 1WCM252_Z3_1 15 20170145 102517667 −0.0171 −0.0139 1.0054 0.9755 1 1WCM252_Z3_1 16 67604 90162150 −0.0031 0.0053 1.0147 0.9927 1 1WCM252_Z3_1 17 131595 3680928 0.0133 0.0278 1.05 0.9889 1 1 WCM252_Z3_117 3704410 16594009 −0.6581 −0.9929 1.0233 −0.0183 1 0 WCM252_Z3_1 1716594048 56350247 −0.0106 −0.0049 1.0116 0.9816 1 1 WCM252_Z3_1 1756350921 56599428 −0.599 −0.8918 1.0079 0.07 1 0 WCM252_Z3_1 17 5660249681083561 0.0022 0.0126 1.0143 1.0033 1 1 WCM252_Z3_1 18 48341 83945520.0051 0.0165 1.0267 0.9963 1 1 WCM252_Z3_1 18 8406156 10871384 −0.6217−0.9303 1.0472 0.0023 1 0 WCM252_Z3_1 18 10979629 74980815 −0.021−0.0192 0.9868 0.9868 1 1 WCM252_Z3_1 18 76856583 78005199 −0.5668−0.8379 NA NA NA NA WCM252_Z3_1 19 281503 4660726 −0.6438 −0.9682 1.01950.0028 1 0 WCM252_Z3_1 19 4668644 24310661 −0.0085 −0.002 1.0054 0.99171 1 WCM252_Z3_1 19 29567134 31769483 2.9223 3.3313 NA NA NA NAWCM252_Z3_1 19 31769763 33702026 −0.6675 −1.0093 0.9934 2.00E−04 1 0WCM252_Z3_1 19 33702390 34513633 2.8041 3.2086 NA NA NA NA WCM252_Z3_119 34513852 38055827 −0.6926 −1.0533 0.9665 −0.0028 1 0 WCM252_Z3_1 1938056158 38388864 2.7631 3.1659 NA NA NA NA WCM252_Z3_1 19 3857234339382581 −0.6483 −0.9759 1.0143 0.0025 1 0 WCM252_Z3_1 19 3938456440275185 2.9418 3.3515 19.3875 1.0263 19  1 WCM252_Z3_1 19 4027646140978590 3.4077 3.8317 27.649 0.828 28  1 WCM252_Z3_1 19 4099365041404085 2.7532 3.1555 17.0498 0.7716 17  1 WCM252_Z3_1 19 4140596248968015 −0.6711 −1.0155 0.9848 0.0045 1 0 WCM252_Z3_1 19 4897326359083985 −0.0303 −0.0321 0.9888 0.9672 1 1 WCM252_Z3_1 2 41612 61019325−0.0306 −0.0325 0.9926 0.9629 1 1 WCM252_Z3_1 2 61020808 62738946−0.6591 −0.9947 NA NA NA NA WCM252_Z3_1 2 62934328 127826533 −0.0203−0.0182 1.0119 0.963 1 1 WCM252_Z3_1 2 127827580 131595261 −0.5579−0.8232 1.0822 0.0481 1 0 WCM252_Z3_1 2 131671631 179843334 −0.0030.0055 1.0175 0.9901 1 1 WCM252_Z3_1 2 179912030 196545161 −0.6648−1.0047 0.982 0.0148 1 0 WCM252_Z3_1 2 196545513 219959996 −0.0133−0.0086 1.0254 0.9627 1 1 WCM252_Z3_1 2 220011408 228993243 −0.6508−0.9803 1.0171 −0.0034 1 0 WCM252_Z3_1 2 228996781 233438805 −0.00250.0062 1.1005 0.9081 1 1 WCM252_Z3_1 2 233445763 237300993 −0.6493−0.9777 1.0274 −0.0118 1 0 WCM252_Z3_1 2 237349734 242946604 0.01050.0239 1.025 1.0084 1 1 WCM252_Z3_1 20 68375 62904847 −0.0123 −0.00721.0018 0.9882 1 1 WCM252_Z3_1 21 9826205 39817361 −0.0263 −0.0265 1.01160.9521 1 1 WCM252_Z3_1 21 39818741 43134216 −0.706 −1.0772 0.9617−0.0138 1 0 WCM252_Z3_1 21 43134276 48084282 −0.0237 −0.023 0.99770.9707 1 1 WCM252_Z3_1 22 16287467 51215142 −0.0182 −0.0153 1.00030.9785 1 1 WCM252_Z3_1 3 239405 44893778 −0.0037 0.0045 1.0031 1.0031 11 WCM252_Z3_1 3 44903385 89521693 −0.6605 −0.9972 0.9913 0.0107 1 0WCM252_Z3_1 3 89528644 176750860 0.4149 0.5512 1.9424 0.9882 2 1WCM252_Z3_1 3 176756215 184550501 0.0031 0.0138 1.0496 0.9696 1 1WCM252_Z3_1 3 184552483 197894719 0.4285 0.5682 1.9995 0.9658 2 1WCM252_Z3_1 4 59331 2087469 0.0108 0.0243 1.0267 1.0073 1 1 WCM252_Z3_14 2097647 2515531 −0.6307 −0.9457 NA NA NA NA WCM252_Z3_1 4 25980553088697 −0.0238 −0.0231 NA NA NA NA WCM252_Z3_1 4 3101043 5894571−0.6548 −0.9871 0.9233 0.0857 1 0 WCM252_Z3_1 4 5925054 190426570−0.0156 −0.0118 1.0068 0.9769 1 1 WCM252_Z3_1 5 140532 49699283 −0.0208−0.019 1.0018 0.972 1 1 WCM252_Z3_1 5 49706767 68550493 −0.6732 −1.01920.9699 0.0169 1 0 WCM252_Z3_1 5 68551401 118729066 −0.0275 −0.02810.9982 0.9631 1 1 WCM252_Z3_1 5 118788464 132270123 −0.6614 −0.99870.9382 0.0627 1 0 WCM252_Z3_1 5 132270461 153190635 −0.0155 −0.01160.992 0.992 1 1 WCM252_Z3_1 5 153372563 154336695 −0.645 −0.9702 NA NANA NA WCM252_Z3_1 5 154346250 180687803 0.0032 0.0139 1.0207 0.9986 1 1WCM252_Z3_1 6 203552 24357971 −0.0054 0.0023 1.018 0.9851 1 1WCM252_Z3_1 6 24403380 26056549 −0.6224 −0.9315 1.0608 −0.0122 1 0WCM252_Z3_1 6 26087705 165809845 −0.0123 −0.0073 1.0059 0.984 1 1WCM252_Z3_1 6 165827133 170893407 −0.6579 −0.9926 0.985 0.0201 1 0WCM252_Z3_1 7 193451 1276154 0.01 0.0233 1.1119 0.9206 1 1 WCM252_Z3_1 71473997 4218187 −0.6271 −0.9395 1.0339 0.0089 1 0 WCM252_Z3_1 7 42455157646687 0.0022 0.0126 1.0294 0.9881 1 1 WCM252_Z3_1 7 7676634 16503950−0.6108 −0.9117 0.9958 0.0673 1 0 WCM252_Z3_1 7 16505238 18330136−1.6571 −3.9082 NA NA NA NA WCM252_Z3_1 7 18498491 20698710 −0.6784−1.0284 NA NA NA NA WCM252_Z3_1 7 20706390 53104210 −0.0055 0.00211.0138 0.9891 1 1 WCM252_Z3_1 7 54610425 57529635 −0.6534 −0.9848 NA NANA NA WCM252_Z3_1 7 63529293 107303789 −0.013 −0.0082 1.0121 0.9766 1 1WCM252_Z3_1 7 107312675 108524568 −0.5946 −0.8844 NA NA NA NAWCM252_Z3_1 7 109599726 157060397 −0.0027 0.0059 1.0124 0.9959 1 1WCM252_Z3_1 7 157151328 158937022 −0.4036 −0.5762 NA NA NA NAWCM252_Z3_1 8 190907 23174487 −0.0066  5.00E−04 1.0154 0.9853 1 1WCM252_Z3_1 8 23177553 28047189 −0.6624 −1.0005 0.9608 0.0389 1 0WCM252_Z3_1 8 28186691 47759684 −0.008 −0.0014 1.0223 0.9757 1 1WCM252_Z3_1 8 47842465 59360111 −0.6326 −0.9489 1.0774 −0.0413 1 0WCM252_Z3_1 8 59404150 60031477 −1.7298 −4.469 NA NA NA NA WCM252_Z3_1 861121416 69730480 −0.6413 −0.9639 1.0254 −1.00E−04  1 0 WCM252_Z3_1 870476343 146279527 −0.0023 0.0064 1.0251 0.9838 1 1 WCM252_Z3_1 9 1707933676526 −0.6641 −1.0034 1.0105 −0.0128 1 0 WCM252_Z3_1 9 3379480935555075 −0.037 −0.0412 NA NA NA NA WCM252_Z3_1 9 35555520 88162058−0.6553 −0.988 0.9709 0.0374 1 0 WCM252_Z3_1 9 88190371 141111414−0.0108 −0.0052 1.0073 0.9855 1 1 WCM252_Z3_1 X 2700139 154509348 −0.055−0.0661 NA NA NA NA WCM253 1 17459 249213964 −0.0055 0.1827 1.135 1.1351 1 WCM253 10 225982 135477897 −0.0271 −0.0776 0.9476 0.9476 1 1 WCM25311 193096 62327358 −0.0107 0.1239 1.0897 1.0897 1 1 WCM253 11 6232779867377973 −0.1438 NA −0.0201 −0.0201 0 0 WCM253 11 67378574 134605959−0.01 0.1315 1.0954 1.0954 1 1 WCM253 12 148465 133810710 −0.0393−0.2474 0.8424 0.8424 1 1 WCM253 13 19041965 115089411 −0.0445 −0.32580.7979 0.7979 1 1 WCM253 14 19110239 107283270 −0.0288 −0.101 0.93240.9324 1 1 WCM253 15 20083896 102506282 −0.0163 0.0578 1.0409 1.0409 1 1WCM253 16 97550 90234899 −0.0377 −0.2236 0.8564 0.8564 1 1 WCM253 17131595 81052545 −0.037 −0.2147 0.8617 0.8617 1 1 WCM253 18 4759278005164 −0.0328 −0.1553 0.8979 0.8979 1 1 WCM253 19 105050 59093696−0.0397 −0.2529 0.8392 0.8392 1 1 WCM253 2 41620 243037116 −0.01840.0326 1.0229 1.0229 1 1 WCM253 20 68423 62934618 −0.0037 0.2024 1.15061.1506 1 1 WCM253 21 9590301 48084202 −0.0375 −0.2209 0.858 0.858 1 1WCM253 22 16159014 51219090 0.0019 0.2631 1.2001 1.2001 1 1 WCM253 3239349 197896700 −0.0178 0.0398 1.028 1.028 1 1 WCM253 4 53446 190903980−0.0256 −0.0588 0.9601 0.9601 1 1 WCM253 5 90784 180687828 −0.0223−0.0158 0.9891 0.9891 1 1 WCM253 6 203561 170892848 −0.0494 −0.40240.7566 0.7566 1 1 WCM253 7 193171 158937185 −0.0267 −0.0734 0.95040.9504 1 1 WCM253 8 163470 146279453 −0.0287 −0.099 0.9337 0.9337 1 1WCM253 9 73203 141107495 −0.0081 0.1537 1.1124 1.1124 1 1 WCM253 X2700163 154507335 −0.0385 −0.2355 NA NA NA NA WCM253_Z1_1 1 69569120468283 −0.1487 0.606 2.0585 0.9855 2 1 WCM253_Z1_1 1 120469231145682077 0.6058 1.6064 4.6306 1.4592 5 1 WCM253_Z1_1 1 145683579157653025 0.4115 1.3639 3.0346 2.1129 3 2 WCM253_Z1_1 1 157659649159750941 −0.0426 0.7579 2.0132 1.369 2 1 WCM253_Z1_1 1 159751148198703332 0.3478 1.2825 2.8704 1.9947 3 2 WCM253_Z1_1 1 198711139215781395 0.7002 1.7215 3.3537 3.2419 3 3 WCM253_Z1_1 1 215791431249212388 0.0699 0.9142 3.7779 −0.0088 4 0 WCM253_Z1_1 10 25587338679844 −0.5974 −0.1057 1.9104 −0.0517 2 0 WCM253_Z1_1 10 3914711973122353 0.1204 0.9829 2.0165 1.9364 2 2 WCM253_Z1_1 10 7315706689312198 −0.4828 0.0891 2.0925 0.0349 2 0 WCM253_Z1_1 10 8941974490580238 −1.5302 −2.681 NA NA NA NA WCM253_Z1_1 10 90582744 135440108−0.5154 0.0347 2.0439 0.0048 2 0 WCM253_Z1_1 11 193112 15263652 −0.21880.5027 1.8582 0.9755 2 1 WCM253_Z1_1 11 15267468 30928177 0.3723 1.31392.9632 2.0089 3 2 WCM253_Z1_1 11 30930590 47823386 0.125 0.9892 2.00651.9637 2 2 WCM253_Z1_1 11 47826104 48131610 0.4492 1.4116 NA NA NA NAWCM253_Z1_1 11 48134424 64981522 −0.1072 0.6659 2.0246 1.1485 2 1WCM253_Z1_1 11 64981837 73689104 −0.1489 0.6056 2.1223 0.9209 2 1WCM253_Z1_1 11 73689423 74054403 −0.0234 0.7849 NA NA NA NA WCM253_Z1_111 74056686 92087892 0.2326 1.1327 2.4092 1.976 2 2 WCM253_Z1_1 1192088270 103157068 −0.1668 0.5794 2.0678 0.9207 2 1 WCM253_Z1_1 11103158316 134856562 −0.5184 0.0296 2.0176 0.024 2 0 WCM253_Z1_1 12148811 1967752 0.2061 1.0977 2.1883 2.0919 2 2 WCM253_Z1_1 12 196933549434086 0.0681 0.9119 1.9098 1.8531 2 2 WCM253_Z1_1 12 4943434993881384 0.246 1.1502 2.2661 2.1729 2 2 WCM253_Z1_1 12 93898134133810874 −0.1736 0.5695 3.0027 −0.0347 3 0 WCM253_Z1_1 13 1960051530857822 −0.2317 0.4834 1.8396 0.9564 2 1 WCM253_Z1_1 13 3103562960348886 −0.9813 −0.8627 1.0379 0.0619 1 0 WCM253_Z1_1 13 60384944115089411 −0.1869 0.5499 1.9411 0.9868 2 1 WCM253_Z1_1 14 1937771631097471 0.6097 1.6112 4.1463 1.9638 4 2 WCM253_Z1_1 14 31099738107283203 0.523 1.5041 4.6903 0.9825 5 1 WCM253_Z1_1 15 2017012235275599 −0.1773 0.564 1.8131 1.1437 2 1 WCM253_Z1_1 15 3566439947873549 −0.504 0.0539 2.1281 −0.052 2 0 WCM253_Z1_1 15 4805207370961375 −0.1802 0.5598 1.9274 1.0207 2 1 WCM253_Z1_1 15 7096168981282019 −0.4989 0.0623 1.0737 1.0145 1 1 WCM253_Z1_1 15 8128981488727457 −0.2106 0.5149 1.9216 0.9361 2 1 WCM253_Z1_1 15 8879917490016029 −0.643 −0.1864 0.9339 0.8237 1 1 WCM253_Z1_1 15 90020057102506276 −0.1465 0.6091 2.0426 1.008 2 1 WCM253_Z1_1 16 97541 200435060.1467 1.0184 2.2133 1.8379 2 2 WCM253_Z1_1 16 20043735 49433056 −0.15880.5912 2.0744 0.9385 2 1 WCM253_Z1_1 16 49525190 70765429 −0.4584 0.12912.1757 0.0116 2 0 WCM253_Z1_1 16 70778474 74339202 0.145 1.0161 2.12571.9192 2 2 WCM253_Z1_1 16 74339594 90233622 −0.5194 0.028 2.0654 −0.02632 0 WCM253_Z1_1 17 131595 16285747 −0.5128 0.0392 2.0575 −0.0025 2 0WCM253_Z1_1 17 16321061 16344386 0.2253 1.123 NA NA NA NA WCM253_Z1_1 1716344726 19648426 0.1812 1.0645 2.1834 1.9995 2 2 WCM253_Z1_1 1719651682 26488217 −0.5117 0.0409 1.5907 0.4669 2 0 WCM253_Z1_1 1726490633 37341052 0.1624 1.0395 2.0995 2.0115 2 2 WCM253_Z1_1 1737341385 44827171 0.4232 1.3788 3.0783 2.1227 3 2 WCM253_Z1_1 1744828970 75398418 0.154 1.0282 3.0457 1.0332 3 1 WCM253_Z1_1 17 7539877480159616 −0.0334 0.7709 2.4556 0.9572 2 1 WCM253_Z1_1 17 8015966980320400 0.2077 1.0998 NA NA NA NA WCM253_Z1_1 17 80332251 810835670.8326 1.8803 6.4038 0.9594 6 1 WCM253_Z1_1 18 48236 53696076 0.04870.8852 1.8725 1.8216 2 2 WCM253_Z1_1 18 53723847 67992210 0.328 1.2572.5288 2.2511 3 2 WCM253_Z1_1 18 67992484 70532807 −0.0451 0.7544 NA NANA NA WCM253_Z1_1 18 71740779 78005226 −0.7282 −0.3426 1.5274 0.0498 2 0WCM253_Z1_1 19 281435 3805998 −0.1333 0.6283 2.1127 0.9789 2 1WCM253_Z1_1 19 3808876 16687318 −0.5369 −0.0015 1.1649 0.8329 1 1WCM253_Z1_1 19 16687574 17845156 0.6428 1.6517 5.1221 1.1622 5 1WCM253_Z1_1 19 17865979 18885764 0.0417 0.8755 2.3811 1.2883 2 1WCM253_Z1_1 19 18886579 43568748 −0.1659 0.5808 1.9535 1.0378 2 1WCM253_Z1_1 19 43570713 50391765 0.2197 1.1156 3.2113 1.1223 3 1WCM253_Z1_1 19 50393182 57839567 0.0282 0.8569 2.6256 0.9966 3 1WCM253_Z1_1 19 57839678 59083923 0.2112 1.1043 3.0632 1.2368 3 1WCM253_Z1_1 2 41609 97560812 0.1154 0.9761 1.9911 1.9432 2 2 WCM253_Z1_12 97568441 144525573 −0.2021 0.5275 1.9584 0.9244 2 1 WCM253_Z1_1 2144704631 148674856 0.1275 0.9926 NA NA NA NA WCM253_Z1_1 2 148676071170367093 0.4216 1.3767 2.6888 2.5045 3 3 WCM253_Z1_1 2 170367356206608039 0.0386 0.8713 2.8364 0.8221 3 1 WCM253_Z1_1 2 206608278242946607 −0.2273 0.49 2.8236 −0.0147 3 0 WCM253_Z1_1 20 68373 419927−0.4851 0.0852 1.1697 0.952 1 1 WCM253_Z1_1 20 420894 1963643 −1.0747−1.0837 0.8872 0.0565 1 0 WCM253_Z1_1 20 2082677 20349226 −0.486 0.08381.0879 1.0317 1 1 WCM253_Z1_1 20 20349746 30602830 −0.1685 0.577 1.98590.9976 2 1 WCM253_Z1_1 20 30605642 31873994 −0.5712 −0.0602 0.99550.9227 1 1 WCM253_Z1_1 20 31876576 33867903 −0.0192 0.7908 2.1836 1.27662 1 WCM253_Z1_1 20 33868618 35632100 0.4674 1.4345 NA NA NA NAWCM253_Z1_1 20 35635934 44351065 −0.1084 0.6642 1.6531 1.5163 2 2WCM253_Z1_1 20 44352620 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109195587132390687 0.3928 1.3401 2.893 2.1702 3 2 WCM253_Z1_1 3 132390911168542644 0.1379 1.0065 2.0766 1.9414 2 2 WCM253_Z1_1 3 168546991190578594 0.4257 1.3819 2.8835 2.3289 3 2 WCM253_Z1_1 3 190930341197894712 −0.0552 0.7401 2.0937 1.2469 2 1 WCM253_Z1_1 4 59345 3040147−0.5352 0.0013 1.1756 0.8262 1 1 WCM253_Z1_1 4 3042322 37633055 −0.8849−0.6531 0.9393 0.3325 1 0 WCM253_Z1_1 4 37636680 38829989 −0.2997 0.3803NA NA NA NA WCM253_Z1_1 4 38830234 155749212 −0.552 −0.0272 1.12720.8355 1 1 WCM253_Z1_1 4 156135228 190426570 −0.2257 0.4923 1.84170.9716 2 1 WCM253_Z1_1 5 140532 56170944 −0.0581 0.7361 2.2156 1.1156 21 WCM253_Z1_1 5 56171126 125696034 −0.4695 0.1109 1.2112 0.9486 1 1WCM253_Z1_1 5 125707167 180687812 −0.1981 0.5334 1.8951 0.9996 2 1WCM253_Z1_1 6 203624 3751682 −0.538 −0.0034 1.7406 0.2546 2 0WCM253_Z1_1 6 3850216 7585995 0.3164 1.242 2.7999 1.9308 3 2 WCM253_Z1_16 7590624 18130933 −0.2812 0.4086 1.5923 1.0625 2 1 WCM253_Z1_1 618132389 47846965 0.07 0.9144 1.9209 1.8487 2 2 WCM253_Z1_1 6 4784726257244780 −0.5177 0.0308 2.0601 −0.0169 2 0 WCM253_Z1_1 6 5724688472006097 −0.9151 −0.7171 0.8624 0.3542 1 0 WCM253_Z1_1 6 72006512136904711 −0.537 −0.0018 2.0048 −0.0073 2 0 WCM253_Z1_1 6 136913416160222208 −0.2431 0.4663 2.7375 0.0256 3 0 WCM253_Z1_1 6 160224313170893408 −0.5464 −0.0176 1.9588 0.0169 2 0 WCM253_Z1_1 7 193253 331348−0.12 0.6475 NA NA NA NA WCM253_Z1_1 7 539958 30665896 0.0549 0.89371.8885 1.8272 2 2 WCM253_Z1_1 7 30668260 43531763 −0.2352 0.4782 1.78341.0025 2 1 WCM253_Z1_1 7 43532712 64437406 0.0437 0.8783 1.8991 1.7775 22 WCM253_Z1_1 7 64437584 103808935 0.0744 0.9204 2.8189 0.9663 3 1WCM253_Z1_1 7 103824464 104731771 0.0245 0.8518 NA NA NA NA WCM253_Z1_17 104742021 158937400 −0.2323 0.4825 1.8365 0.9578 2 1 WCM253_Z1_1 8190897 12809667 −0.2698 0.426 1.7695 0.9174 2 1 WCM253_Z1_1 8 1284839942761326 −0.556 −0.034 1.9111 0.0423 2 0 WCM253_Z1_1 8 42780709 499877990.3867 1.3323 NA NA NA NA WCM253_Z1_1 8 50449716 55638922 0.8228 1.86875.8648 1.4395 6 1 WCM253_Z1_1 8 55647242 69243602 0.2471 1.1517 2.84881.5946 3 2 WCM253_Z1_1 8 69351868 82751929 0.4813 1.452 3.9161 1.5557 42 WCM253_Z1_1 8 82752126 134267581 0.2505 1.1561 2.7781 1.6789 3 2WCM253_Z1_1 8 134269104 146279472 −0.2017 0.528 2.8864 −0.0026 3 0WCM253_Z1_1 9 17056 1057249 0.0068 0.8272 2.0335 1.515 2 2 WCM253_Z1_1 92029140 19446231 0.2304 1.1298 2.566 1.8106 3 2 WCM253_Z1_1 9 1945044979326097 0.0085 0.8295 1.9724 1.5818 2 2 WCM253_Z1_1 9 79326270 82337885−0.3267 0.3387 NA NA NA NA WCM253_Z1_1 9 82339978 98242669 −0.8091−0.4987 1.4315 −0.016 1 0 WCM253_Z1_1 9 98244421 98783187 −0.5029 0.0557NA NA NA NA WCM253_Z1_1 9 98783369 133947012 −0.3076 0.3682 2.5874−0.0059 3 0 WCM253_Z1_1 9 133948049 141111414 −0.1929 0.541 3.0266−0.1166 3 0 WCM253_Z1_1 X 2700163 63410922 −0.0175 0.7932 NA NA NA NAWCM253_Z1_1 X 63411160 145109356 −0.557 −0.0357 NA NA NA NA WCM253_Z1_1X 147800748 154509348 0.0849 0.9348 NA NA NA NA WCM261 1 14860 2492139730.0349 NA NA NA NA NA WCM261 10 226106 135477898 0.0235 NA NA NA NA NAWCM261 11 193146 134605849 0.0169 NA NA NA NA NA WCM261 12 148388133810892 0.0029 NA NA NA NA NA WCM261 13 19041979 115089411 −0.0069 NANA NA NA NA WCM261 14 19110297 107283269 0.014 NA NA NA NA NA WCM261 1520083887 102515229 0.0363 NA NA NA NA NA WCM261 16 83338 90260461 0.0065NA NA NA NA NA WCM261 17 131595 81187849 0.026 NA NA NA NA NA WCM261 1847686 78005145 −0.004 NA NA NA NA NA WCM261 19 105010 59093696 −0.0067NA NA NA NA NA WCM261 2 41662 243037019 0.0094 NA NA NA NA NA WCM261 2068337 62934623 0.0462 NA NA NA NA NA WCM261 21 9590331 48084201 0.0142NA NA NA NA NA WCM261 22 16159046 51216331 0.0524 NA NA NA NA NA WCM2613 239431 197896700 0.0189 NA NA NA NA NA WCM261 4 53377 190903980 0.0088NA NA NA NA NA WCM261 5 90576 180687576 0.0022 NA NA NA NA NA WCM261 6203516 170892848 0.008 NA NA NA NA NA WCM261 7 195656 158937013−5.00E−04 NA NA NA NA NA WCM261 8 163470 146279529 0.0056 NA NA NA NA NAWCM261 9 14908 141107582 0.0292 NA NA NA NA NA WCM261 X 2700139154493406 −0.1254 NA NA NA NA NA WCM261_Z4_1 1 69640 145112428 −0.36560.1398 1.1263 1.0772 1 1 WCM261_Z4_1 1 145115810 190424021 0.1862 1.09783.2188 1.0619 3 1 WCM261_Z4_1 1 192128396 193121560 −0.8586 −1.1315 NANA NA NA WCM261_Z4_1 1 193149667 249212550 0.185 1.096 3.1726 1.1025 3 1WCM261_Z4_1 10 225958 135440086 −0.3527 0.1657 2.2014 0.042 2 0WCM261_Z4_1 11 193112 2161519 −0.3226 0.2254 1.6514 0.6868 2 1WCM261_Z4_1 11 2161950 102496036 −0.0504 0.7189 2.1841 1.1079 2 1WCM261_Z4_1 11 102554079 110697305 −0.324 0.2227 1.6648 0.669 2 1WCM261_Z4_1 11 111152166 134856626 0.1646 1.0648 2.1208 2.0629 2 2WCM261_Z4_1 12 148673 122626860 0.1714 1.0753 2.133 2.0813 2 2WCM261_Z4_1 12 122657189 133810703 −0.339 0.193 2.1423 0.144 2 0WCM261_Z4_1 13 19600365 32313777 0.3689 1.3683 4.1581 1.0052 4 1WCM261_Z4_1 13 32332471 39265108 0.0721 0.9199 2.9398 0.8442 3 1WCM261_Z4_1 13 39265305 39541159 0.346 1.3353 NA NA NA NA WCM261_Z4_1 1339542673 90883435 −0.7321 −0.7333 1.1497 0.0534 1 0 WCM261_Z4_1 1392003159 115089411 0.1684 1.0706 3.1591 1.0415 3 1 WCM261_Z4_1 1419377703 57099859 −0.0551 0.7111 2.1541 1.1201 2 1 WCM261_Z4_1 1457101660 82000024 −0.3627 0.1456 1.1397 1.0727 1 1 WCM261_Z4_1 1485995090 107283094 −0.069 0.6875 2.1308 1.0903 2 1 WCM261_Z4_1 1520170134 41988440 −0.734 −0.7386 1.1796 0.0191 1 0 WCM261_Z4_1 1541988711 102517662 −0.0805 0.6679 2.1158 1.0618 2 1 WCM261_Z4_1 16 9754046615932 −0.0576 0.7069 2.1788 1.0859 2 1 WCM261_Z4_1 16 4661743971884775 −0.371 0.1287 1.14 1.0467 1 1 WCM261_Z4_1 16 71884997 90233626−0.7056 −0.6582 1.1903 0.0771 1 0 WCM261_Z4_1 17 131595 81083567 −0.06690.6912 2.1219 1.1073 2 1 WCM261_Z4_1 18 48201 78005214 −0.3592 0.15262.1416 0.0815 2 0 WCM261_Z4_1 19 281506 21992341 −0.0677 0.6898 2.15571.0704 2 1 WCM261_Z4_1 19 21992542 48176995 −0.36 0.151 1.3274 0.8932 11 WCM261_Z4_1 19 48179138 59083953 0.1303 1.0116 2.9624 1.0699 3 1WCM261_Z4_1 2 41613 47797392 0.1571 1.0532 3.0905 1.0599 3 1 WCM261_Z4_12 47905398 70528091 −0.1267 0.588 3.0238 −0.0175 3 0 WCM261_Z4_1 270528601 106015995 −0.0913 0.6495 2.1537 0.9835 2 1 WCM261_Z4_1 2106471734 115991546 −0.4138 0.0404 1.9598 0.097 2 0 WCM261_Z4_1 2116066907 125669051 −0.0608 0.7014 1.9098 1.3425 2 1 WCM261_Z4_1 2125671800 157369859 −0.4031 0.0629 2.0763 0.0127 2 0 WCM261_Z4_1 2157406249 242946607 −0.1162 0.6064 2.0101 1.0348 2 1 WCM261_Z4_1 2068351 397883 0.0676 0.9126 NA NA NA NA WCM261_Z4_1 20 398171 256662110.2061 1.1281 2.2155 2.1559 2 2 WCM261_Z4_1 20 25666642 62904845 −0.04620.7261 2.1605 1.1479 2 1 WCM261_Z4_1 21 9826203 48084277 0.1601 1.05782.1362 2.0271 2 2 WCM261_Z4_1 22 16287449 51215124 −0.0639 0.6962 2.15891.0817 2 1 WCM261_Z4_1 3 239349 17550038 0.1808 1.0896 3.2448 1.0114 3 1WCM261_Z4_1 3 18055231 23258777 −0.4257 0.0155 NA NA NA NA WCM261_Z4_1 323312442 74316427 0.2051 1.1267 3.22 1.1471 3 1 WCM261_Z4_1 3 74334621197894719 0.3827 1.388 3.1677 2.0667 3 2 WCM261_Z4_1 4 59345 111542124−0.0529 0.7148 2.1314 1.1512 2 1 WCM261_Z4_1 4 111542366 133367616−0.3854 0.0993 2.1773 −0.0348 2 0 WCM261_Z4_1 4 133368196 138442573−1.3657 NA NA NA NA NA WCM261_Z4_1 4 138442795 138453409 −0.3506 0.1699NA NA NA NA WCM261_Z4_1 4 139100391 190426502 −0.0333 0.7477 2.20951.1486 2 1 WCM261_Z4_1 5 140532 31294164 −0.0421 0.7329 2.1976 1.1264 21 WCM261_Z4_1 5 31294357 49699122 0.1863 1.0981 3.0231 1.2582 3 1WCM261_Z4_1 5 49706767 53606301 −0.0963 0.6408 NA NA NA NA WCM261_Z4_1 553751868 90672527 −0.3797 0.1111 1.1264 1.0337 1 1 WCM261_Z4_1 590678654 112927740 −0.6583 −0.5304 1.1947 0.19 1 0 WCM261_Z4_1 5113698581 118850687 −0.2379 0.3874 1.4371 1.179 1 1 WCM261_Z4_1 5118860935 180687766 0.19 1.1037 3.2008 1.0972 3 1 WCM261_Z4_1 6 20350922570189 −0.3321 0.2068 1.1929 1.1153 1 1 WCM261_Z4_1 6 2257046468599049 −0.0722 0.6822 2.0854 1.1237 2 1 WCM261_Z4_1 6 6934881969945012 −0.457 −0.0517 NA NA NA NA WCM261_Z4_1 6 69949086 102516268−0.7447 −0.7697 1.1488 0.0243 1 0 WCM261_Z4_1 6 105177609 126332504−0.3639 0.1432 2.1288 0.0799 2 0 WCM261_Z4_1 6 126334135 170893406−0.0792 0.6701 2.1078 1.0746 2 1 WCM261_Z4_1 7 193205 8043669 −0.03860.7389 2.2813 1.0564 2 1 WCM261_Z4_1 7 8062198 57529304 0.2298 1.1642.2845 2.197 2 2 WCM261_Z4_1 7 57529644 110764849 0.3862 1.393 3.1482.1044 3 2 WCM261_Z4_1 7 111032062 113558694 0.1756 1.0817 NA NA NA NAWCM261_Z4_1 7 114066583 115624478 −1.3012 −4.7226 NA NA NA NAWCM261_Z4_1 7 115750875 154002623 0.205 1.1265 2.2297 2.137 2 2WCM261_Z4_1 7 154143361 156786875 −0.2749 0.3178 2.2649 0.2279 2 0WCM261_Z4_1 7 156798302 158937203 0.2307 1.1653 NA NA NA NA WCM261_Z4_18 190907 8239230 0.5603 1.6359 3.29 2.9257 3 3 WCM261_Z4_1 8 855990832621591 −0.0745 0.6782 3.1687 0.0317 3 0 WCM261_Z4_1 8 3323024457905962 0.5825 1.666 3.2336 3.1132 3 3 WCM261_Z4_1 8 59058907 652860100.1501 1.0424 NA NA NA NA WCM261_Z4_1 8 65290081 82752149 0.5804 1.66333.4079 2.9268 3 3 WCM261_Z4_1 8 85097244 87497188 −0.084 0.662 NA NA NANA WCM261_Z4_1 8 87498764 113812467 0.5501 1.6219 3.2629 2.8928 3 3WCM261_Z4_1 8 113841912 118184872 −0.0506 0.7188 NA NA NA NA WCM261_Z4_18 118533170 146279489 0.606 1.6979 3.2442 3.2442 3 3 WCM261_Z4_1 9 17074141111414 −0.0593 0.7041 2.1694 1.0888 2 1 WCM261_Z4_1 X 270014764141841 −0.3873 0.0954 NA NA NA NA WCM261_Z4_1 X 64196252 680496912.4189 3.8311 NA NA NA NA WCM261_Z4_1 X 68058523 109419611 0.1646 1.0647NA NA NA NA WCM261_Z4_1 X 109441769 109698481 −0.9619 −1.5272 NA NA NANA WCM261_Z4_1 X 109919491 154509348 0.1631 1.0624 NA NA NA NA WCM2_Z3_11 69592 109200198 −0.162 −0.0117 1.0128 0.9711 1 1 WCM2_Z3_1 1 109202492110527726 −0.4807 −0.909 1.1142 −0.049 1 0 WCM2_Z3_1 1 110551727205767885 −0.1618 −0.0112 1.0177 0.9668 1 1 WCM2_Z3_1 1 205768191216172264 −0.5283 −1.0821 1.0423 −0.0976 1 0 WCM2_Z3_1 1 216173794236208773 −0.1864 −0.0692 1.8646 0.0417 2 0 WCM2_Z3_1 1 236212176249212557 0.0352 0.413 1.5945 1.0684 2 1 WCM2_Z3_1 10 225988 293361−0.2338 −0.1853 NA NA NA NA WCM2_Z3_1 10 294457 82012599 0.0613 0.46461.913 0.847 2 1 WCM2_Z3_1 10 82013146 88466450 −0.108 0.1114 2.1220.0385 2 0 WCM2_Z3_1 10 88469733 135440108 −0.258 −0.2469 0.8796 0.80581 1 WCM2_Z3_1 11 193112 533360 0.2277 0.7747 2.567 0.8545 3 1 WCM2_Z3_111 533611 34654150 0.1449 0.6242 2.711 0.3716 3 0 WCM2_Z3_1 11 34668175134856523 0.0398 0.4221 1.8517 0.8281 2 1 WCM2_Z3_1 12 148674 98474650.1212 0.5797 1.9401 1.0489 2 1 WCM2_Z3_1 12 9871328 32137512 −0.213−0.1338 1.8398 −0.0169 2 0 WCM2_Z3_1 12 32137682 125263024 0.0967 0.53311.9905 0.9036 2 1 WCM2_Z3_1 12 125267352 133810703 −0.1952 −0.09051.8384 0.0401 2 0 WCM2_Z3_1 13 19600475 115089411 −0.2179 −0.1457 1.8515−0.0436 2 0 WCM2_Z3_1 14 19377703 59113147 0.2454 0.8058 2.1323 1.3639 21 WCM2_Z3_1 14 59113430 74439698 −0.1825 −0.06 1.9372 −0.0187 2 0WCM2_Z3_1 14 74440597 86089622 0.1144 0.5669 1.7508 1.2119 2 1 WCM2_Z3_114 86089790 95670564 0.2789 0.8642 2.8615 0.779 3 1 WCM2_Z3_1 1495670669 95875449 −0.0036 0.3344 NA NA NA NA WCM2_Z3_1 14 95875689105964244 0.5136 1.2486 2.824 1.9282 3 2 WCM2_Z3_1 14 105965102107283080 0.4259 1.1096 NA NA NA NA WCM2_Z3_1 15 20169912 102506276−0.1957 −0.0917 0.9633 0.9135 1 1 WCM2_Z3_1 16 66930 47007464 0.38531.0435 2.0782 2.0443 2 2 WCM2_Z3_1 16 47117174 90233626 −0.169 −0.02811.954 0.0075 2 0 WCM2_Z3_1 17 131595 3324660 −0.5106 −1.0161 0.92950.0595 1 0 WCM2_Z3_1 17 3324810 3979949 0.1305 0.5972 2.035 0.9905 2 1WCM2_Z3_1 17 3980179 4016096 0.0374 0.4173 NA NA NA NA WCM2_Z3_1 174017750 6330367 0.2149 0.7518 3.3842 −0.0165 3 0 WCM2_Z3_1 17 633182210618855 −0.1619 −0.0113 2.0746 −0.0902 2 0 WCM2_Z3_1 17 1062842211532835 −0.4752 −0.8897 NA NA NA NA WCM2_Z3_1 17 11535977 17398632−0.5832 −1.3034 0.708 0.1023 1 0 WCM2_Z3_1 17 17398840 81083567 −0.1577−0.0017 1.1755 0.8222 1 1 WCM2_Z3_1 18 48269 78005215 −0.1607 −0.00871.9125 0.0754 2 0 WCM2_Z3_1 19 281508 40366362 −0.1469 0.0234 2.0445−0.0118 2 0 WCM2_Z3_1 19 40367908 40373952 −1.4168 NA NA NA NA NAWCM2_Z3_1 19 40376653 59083953 −0.1233 0.0772 2.1452 −0.0353 2 0WCM2_Z3_1 2 41615 116573264 0.1135 0.5652 1.9452 1.0139 2 1 WCM2_Z3_1 2116593809 127413870 −0.2028 −0.1089 1.7631 0.0915 2 0 WCM2_Z3_1 2127414170 242946616 0.0996 0.5387 1.9666 0.9387 2 1 WCM2_Z3_1 20 6837360702744 0.148 0.63 1.9383 1.1568 2 1 WCM2_Z3_1 20 60704003 627380250.2915 0.8859 1.8956 1.8003 2 2 WCM2_Z3_1 20 62830252 62919090 0.08670.514 NA NA NA NA WCM2_Z3_1 21 9907304 48084277 −0.2033 −0.11 0.97610.877 1 1 WCM2_Z3_1 22 17063476 51215142 −0.155 0.0046 1.0218 0.9846 1 1WCM2_Z3_1 3 239398 197894712 0.0886 0.5176 1.9334 0.9298 2 1 WCM2_Z3_1 459345 36069616 0.1046 0.5482 1.8832 1.0413 2 1 WCM2_Z3_1 4 3606983352729651 −0.5238 −1.0653 0.9468 0.009 1 0 WCM2_Z3_1 4 52740547 1115435210.0702 0.482 1.8323 0.9611 2 1 WCM2_Z3_1 4 111553577 190426502 0.27250.8532 2.7304 0.8825 3 1 WCM2_Z3_1 5 140532 180687766 0.0651 0.47211.832 0.9422 2 1 WCM2_Z3_1 6 203695 47645620 0.0786 0.4983 1.9492 0.87592 1 WCM2_Z3_1 6 47646842 62284306 −0.2125 −0.1325 1.1696 0.6549 1 1WCM2_Z3_1 6 62390919 170893450 0.0257 0.394 1.8314 0.7967 2 1 WCM2_Z3_17 193436 299850 0.308 0.9142 NA NA NA NA WCM2_Z3_1 7 330227 711422620.3366 0.9626 1.975 1.9226 2 2 WCM2_Z3_1 7 71175907 158937400 0.10040.5403 1.8852 1.0234 2 1 WCM2_Z3_1 8 190908 29814844 −0.1212 0.08192.1598 −0.043 2 0 WCM2_Z3_1 8 29921417 48885436 0.2048 0.7336 2.25451.0711 2 1 WCM2_Z3_1 8 48887432 55612062 0.6175 1.4073 NA NA NA NAWCM2_Z3_1 8 55614082 59483449 1.0097 1.9617 NA NA NA NA WCM2_Z3_1 859484869 77775640 0.4688 1.1782 3.5943 0.9316 4 1 WCM2_Z3_1 8 7777588493329029 0.077 0.4951 1.538 1.2809 2 1 WCM2_Z3_1 8 93897050 1017277290.6764 1.4948 3.4895 2.1469 3 2 WCM2_Z3_1 8 101730409 103541605 1.10042.082 NA NA NA NA WCM2_Z3_1 8 103564040 104709502 −0.1715 −0.0339 NA NANA NA WCM2_Z3_1 8 104778567 110535519 0.4028 1.0721 2.1471 2.0579 2 2WCM2_Z3_1 8 110539186 117859924 −0.1439 0.0302 NA NA NA NA WCM2_Z3_1 8117861249 124798817 0.751 1.6032 NA NA NA NA WCM2_Z3_1 8 124799536127568900 0.1948 0.7156 NA NA NA NA WCM2_Z3_1 8 127569110 136657316−0.4889 −0.9377 0.9304 0.1137 1 0 WCM2_Z3_1 8 139144849 141745372 0.40831.081 NA NA NA NA WCM2_Z3_1 8 141749130 146279545 −0.472 −0.8789 1.03170.0559 1 0 WCM2_Z3_1 9 17116 7046917 −0.5677 −1.2383 0.884 −0.0362 1 0WCM2_Z3_1 9 7049148 88968021 −0.1546 0.0056 1.0435 0.9643 1 1 WCM2_Z3_19 89560852 141111414 0.1543 0.6416 2.1631 0.9569 2 1 WCM2_Z3_1 X 27077242836060 0.9315 1.856 NA NA NA NA WCM2_Z3_1 X 2836211 27999311 0.93961.867 NA NA NA NA WCM2_Z3_1 X 28807515 62885779 0.6368 1.4362 NA NA NANA WCM2_Z3_1 X 62898360 65428076 2.3608 3.5842 NA NA NA NA WCM2_Z3_1 X65474917 68381424 4.1876 5.5211 NA NA NA NA WCM2_Z3_1 X 68381748154509348 −0.2302 −0.1763 NA NA NA NA WCM341 1 14930 156811634 −0.18990.5685 1.9941 0.972 2 1 WCM341 1 156812249 190067028 0.0301 1.09133.1105 1.1508 3 1 WCM341 1 190067420 228473805 −0.129 0.7246 2.19371.1111 2 1 WCM341 1 228474437 248685768 −0.0285 0.9621 2.8098 1.0865 3 1WCM341 1 248737474 249214028 −0.24 0.4317 NA NA NA NA WCM341 10 2261075948533 −0.0418 0.932 2.0429 1.7729 2 2 WCM341 10 5951025 480255970.1238 1.2856 2.4379 2.4379 2 2 WCM341 10 48033087 56106120 0.51751.9895 3.9709 3.9709 4 4 WCM341 10 56129038 65928970 0.2837 1.59 3.04872.9723 3 3 WCM341 10 65929489 79397240 0.5372 2.0212 4.0593 4.0593 4 4WCM341 10 79492257 79589199 0.198 1.4307 NA NA NA NA WCM341 10 79590105101667847 −0.0316 0.9551 3.1584 0.7192 3 1 WCM341 10 101668679 135235510−0.2309 0.4571 1.9001 0.8455 2 1 WCM341 10 135235561 135477892 −0.06840.8706 NA NA NA NA WCM341 11 193112 65233857 0.1803 1.3967 2.633 2.633 33 WCM341 11 65265435 65273799 −0.9926 NA NA NA NA NA WCM341 11 6529265369063668 0.12 1.278 2.425 2.425 2 2 WCM341 11 69456225 71693951 1.52063.381 17.2626 3.573 17  4 WCM341 11 71698125 134605959 0.1887 1.41282.6625 2.6625 3 3 WCM341 12 148388 133810703 −0.0415 0.9327 1.90881.9088 2 2 WCM341 13 19041965 115089411 0.0285 1.0878 2.7293 1.5218 3 2WCM341 14 19110348 107283274 0.0921 1.2213 2.3316 2.3316 2 2 WCM341 1520083905 102506321 −0.0357 0.9459 1.9264 1.9264 2 2 WCM341 16 6442468264699 0.1762 1.3887 2.6185 2.6185 3 3 WCM341 16 68265322 90168857−0.3534 0.0864 2.2446 −0.1211 2 0 WCM341 17 263123 16046845 −0.3825−0.0119 2.0272 −0.0437 2 0 WCM341 17 16049839 71205554 −0.2091 0.51692.1447 0.7172 2 1 WCM341 17 71205854 80541988 −0.092 0.8148 1.83061.6876 2 2 WCM341 17 80543738 80684986 −0.215 0.5008 NA NA NA NA WCM34117 80696325 81187811 −0.2834 0.3058 2.2567 0.2156 2 0 WCM341 18 4771478005194 0.0481 1.1296 2.7999 1.576 3 2 WCM341 19 105021 42585292 0.01091.0496 2.6573 1.4825 3 1 WCM341 19 42585512 45010215 −0.1687 0.62391.7086 1.3735 2 1 WCM341 19 45015182 48249031 −0.0257 0.9686 2.59121.3225 3 1 WCM341 19 48250324 58928786 0.5261 2.0033 5.1716 2.8469 5 3WCM341 19 58929052 59093696 −0.1693 0.6224 NA NA NA NA WCM341 2 41662243037019 −0.2044 0.5296 2.1441 0.743 2 1 WCM341 20 68396 629346180.1518 1.3412 3.4502 1.6169 3 2 WCM341 21 9590301 48084207 −0.11740.7533 2.5785 0.7927 3 1 WCM341 22 16159079 51219138 0.0342 1.1 2.42821.8588 2 2 WCM341 3 239390 113655207 0.1324 1.3027 3.1845 1.7492 3 2WCM341 3 113656972 132075549 −0.5012 −0.474 1.4582 −0.0182 1 0 WCM341 3132075945 197896800 0.1357 1.3094 3.1977 1.7591 3 2 WCM341 4 5333439458051 −0.3611 0.0607 1.1024 0.9836 1 1 WCM341 4 39459154 39460535−1.6505 NA NA NA NA NA WCM341 4 39460797 122137704 −0.3403 0.1292 1.12911.0582 1 1 WCM341 4 122148526 128865030 −0.1355 0.7083 2.3687 0.8991 2 1WCM341 4 128865139 190903980 −0.3611 0.0609 1.092 0.9942 1 1 WCM341 590714 137759916 −0.2332 0.4506 1.9274 0.8058 2 1 WCM341 5 137760083140857380 −0.4037 −0.087 1.5822 0.3008 2 0 WCM341 5 140857868 180687812−0.2291 0.4622 1.9362 0.819 2 1 WCM341 6 203428 66115281 0.113 1.26382.862 1.9406 3 2 WCM341 6 66200400 170892877 −0.0537 0.9047 2.90030.8438 3 1 WCM341 7 193222 158937142 0.3403 1.6911 3.2291 3.2291 3 3WCM341 8 163527 29786035 0.1373 1.3126 3.9635 1.0042 4 1 WCM341 829786342 146279529 0.0563 1.147 4.406 0.023 4 0 WCM341 9 14903 20607890.246 1.521 2.923 2.8167 3 3 WCM341 9 2070400 36372494 0.332 1.67643.1963 3.1963 3 3 WCM341 9 36375867 69847116 −0.0088 1.0064 3.15430.8634 3 1 WCM341 9 69848036 141107539 0.294 1.6086 4.358 1.7411 4 2WCM341 X 2700090 63574833 0.1086 1.255 NA NA NA NA WCM341 X 6357600268062026 1.754 3.6641 NA NA NA NA WCM341 X 68381140 154493589 0.07641.1889 NA NA NA NA WCM341_X1_1_p2 1 69594 43149117 −0.1499 −0.93460.7984 0.2479 1 0 WCM341_X1_1_p2 1 43161872 118617164 −0.2548 −1.27420.6461 0.1808 1 0 WCM341_X1_1_p2 1 118624123 145561594 −0.1967 −1.07920.9169 0.0296 1 0 WCM341_X1_1_p2 1 145561750 158047869 −0.2375 −1.21420.6739 0.1882 1 0 WCM341_X1_1_p2 1 158054237 249212369 −0.08 −0.7350.9045 0.2971 1 0 WCM341_X1_1_p2 10 255922 3181071 −0.0896 −0.7613 NA NANA NA WCM341_X1_1_p2 10 3182988 48033075 0.0771 −0.3407 0.991 0.5883 1 1WCM341_X1_1_p2 10 48370643 79397279 0.3428 0.2139 1.1796 1.14 1 1WCM341_X1_1_p2 10 79552234 135440117 −0.0959 −0.7789 0.8702 0.2954 1 0WCM341_X1_1_p2 11 193112 134856534 0.1357 −0.2083 0.8846 0.8465 1 1WCM341_X1_1_p2 12 148639 133810703 −0.0222 −0.5822 0.8115 0.5244 1 1WCM341_X1_1_p2 13 19600515 115089411 0.001 −0.5235 0.9301 0.4613 1 0WCM341_X1_1_p2 14 19377689 107283055 −0.045 −0.6412 0.6715 0.6109 1 1WCM341_X1_1_p2 15 20170106 102506273 −0.1464 −0.9242 0.6602 0.3937 1 0WCM341_X1_1_p2 16 67604 68224794 0.0257 −0.4626 0.7522 0.6992 1 1WCM341_X1_1_p2 16 68225005 90233312 −0.3508 −1.6446 0.6518 −0.0122 1 0WCM341_X1_1_p2 17 131595 16330085 −0.3376 −1.5891 0.7045 −0.0398 1 0WCM341_X1_1_p2 17 16330769 80847561 −0.2189 −1.1514 0.6365 0.2638 1 0WCM341_X1_1_p2 17 80851476 81083561 −0.3874 −1.807 0.5405 0.0311 1 0WCM341_X1_1_p2 18 48220 78005215 −0.1033 −0.7995 0.7183 0.4308 1 0WCM341_X1_1_p2 19 281467 42621153 −0.0866 −0.7529 0.7797 0.4071 1 0WCM341_X1_1_p2 19 42621545 43699410 −0.36 −1.6841 NA NA NA NAWCM341_X1_1_p2 19 43708085 48202609 −0.0924 −0.7691 0.7512 0.4224 1 0WCM341_X1_1_p2 19 48204609 58944877 0.2655 0.0635 1.2703 0.8197 1 1WCM341_X1_1_p2 19 58945079 59083929 −0.0133 −0.5595 NA NA NA NAWCM341_X1_1_p2 2 41612 242946607 −0.2509 −1.2604 0.6405 0.1943 1 0WCM341_X1_1_p2 20 68396 62904863 0.074 −0.3477 1.111 0.4607 1 0WCM341_X1_1_p2 21 9826205 48084204 −0.1855 −1.0437 0.688 0.2821 1 0WCM341_X1_1_p2 22 17063496 51215137 −0.0462 −0.6445 0.8531 0.4263 1 0WCM341_X1_1_p2 3 239349 113684048 0.0042 −0.5157 0.9744 0.4245 1 0WCM341_X1_1_p2 3 113697110 132051081 −0.4952 −2.3938 0.4316 −0.051 0 0WCM341_X1_1_p2 3 132056357 197894713 0.0042 −0.5156 0.9257 0.4733 1 0WCM341_X1_1_p2 4 59326 190426459 −0.2529 −1.2673 0.5742 0.2567 1 0WCM341_X1_1_p2 5 140532 180687812 −0.1327 −0.8838 0.7572 0.3267 1 0WCM341_X1_1_p2 6 203510 68598936 0.0803 −0.3333 1.0121 0.5754 1 1WCM341_X1_1_p2 6 69348790 170852725 −0.0167 −0.5681 1.0827 0.2663 1 0WCM341_X1_1_p2 6 170855270 170892767 0.457 0.4235 NA NA NA NAWCM341_X1_1_p2 7 193222 158937013 0.3315 0.1924 1.1667 1.1186 1 1WCM341_X1_1_p2 8 190900 30040659 0.2092 −0.0511 1.5429 0.3875 2 0WCM341_X1_1_p2 8 30209634 146157248 0.1152 −0.2538 1.5829 0.0944 2 0WCM341_X1_1_p2 8 146157542 146279513 0.1947 −0.0813 NA NA NA NAWCM341_X1_1_p2 9 17055 36219880 0.3161 0.1629 1.1865 1.0526 1 1WCM341_X1_1_p2 9 36222887 140901323 0.2463 0.0249 1.5094 0.5255 2 1WCM341_X1_1_p2 9 140904475 141111414 0.2214 −0.0258 NA NA NA NAWCM341_X1_1_p2 X 2700151 65486388 0.1255 −0.2308 NA NA NA NAWCM341_X1_1_p2 X 65819482 68725979 3.2749 3.9778 NA NA NA NAWCM341_X1_1_p2 X 68748871 154509348 0.0991 −0.2901 NA NA NA NAWCM341_Z2_1 1 69635 157103911 −0.2593 −0.5891 0.9757 0.3538 1 0WCM341_Z2_1 1 157105454 183913347 −0.0336 −0.2569 1.292 0.3818 1 0WCM341_Z2_1 1 183914597 229738171 −0.2223 −0.5329 1.0133 0.369 1 0WCM341_Z2_1 1 229738236 248366749 −0.0152 −0.2309 1.3443 0.3599 1 0WCM341_Z2_1 1 248366980 249212373 0.0167 −0.1861 NA NA NA NA WCM341_Z2_110 255851 4884039 −0.1838 −0.4752 NA NA NA NA WCM341_Z2_1 10 488463647701275 0.0988 −0.0724 1.0956 0.8065 1 1 WCM341_Z2_1 10 4776932750667132 0.4265 0.3597 1.3126 1.2538 1 1 WCM341_Z2_1 10 5066844850678717 −1.0272 −2.0268 NA NA NA NA WCM341_Z2_1 10 50678858 788683130.52 0.4778 1.4118 1.3734 1 1 WCM341_Z2_1 10 78870062 79397279 0.0231−0.177 NA NA NA NA WCM341_Z2_1 10 79552256 106027158 −0.1221 −0.38431.2042 0.3281 1 0 WCM341_Z2_1 10 106028094 135440105 −0.4005 −0.81080.9958 0.1444 1 0 WCM341_Z2_1 11 193112 14246296 0.2467 0.1265 1.25760.9257 1 1 WCM341_Z2_1 11 14264916 19596868 0.6198 0.6017 2.009 1.026 21 WCM341_Z2_1 11 19735325 134856536 0.2019 0.0671 1.0616 1.0336 1 1WCM341_Z2_1 12 148811 133810703 −0.0524 −0.2837 0.9681 0.6749 1 1WCM341_Z2_1 13 19600515 115089411 0.1136 −0.0522 1.2776 0.6513 1 1WCM341_Z2_1 14 20201875 45711700 0.2692 0.1562 1.1378 1.0909 1 1WCM341_Z2_1 14 45712000 106361508 0.1291 −0.0311 0.9933 0.9641 1 1WCM341_Z2_1 14 106363825 107283063 0.249 0.1296 NA NA NA NA WCM341_Z2_115 20170117 102389747 −0.0617 −0.297 0.9829 0.645 1 1 WCM341_Z2_1 1667604 68217219 0.1987 0.0627 1.0626 1.0263 1 1 WCM341_Z2_1 16 6822491190233297 −0.513 −0.9973 0.9629 0.039 1 0 WCM341_Z2_1 17 131595 15973601−0.5134 −0.9981 0.965 0.0363 1 0 WCM341_Z2_1 17 15973823 74309955−0.2676 −0.6017 0.951 0.367 1 0 WCM341_Z2_1 17 74324870 80786553 −0.0781−0.3205 0.9529 0.6487 1 1 WCM341_Z2_1 17 80788219 81083561 −0.2913−0.6383 0.9615 0.3235 1 0 WCM341_Z2_1 18 48212 78005224 0.0082 −0.19791.0455 0.6981 1 1 WCM341_Z2_1 19 281445 42603965 0.0437 −0.1484 1.13290.6716 1 1 WCM341_Z2_1 19 42621152 42914965 −0.7954 −1.517 NA NA NA NAWCM341_Z2_1 19 42927572 48253479 0.0036 −0.2044 1.052 0.6838 1 1WCM341_Z2_1 19 48254331 58929052 0.634 0.6192 1.8531 1.219 2 1WCM341_Z2_1 19 58943692 59083951 −0.0439 −0.2715 NA NA NA NA WCM341_Z2_12 41620 242946597 −0.2574 −0.5861 0.9785 0.3538 1 0 WCM341_Z2_1 20 6837362904847 0.2753 0.1643 1.574 0.6672 2 1 WCM341_Z2_1 21 9826225 48084281−0.1307 −0.3968 1.1528 0.3663 1 0 WCM341_Z2_1 22 17063496 512151300.0705 −0.1113 1.2387 0.6129 1 1 WCM341_Z2_1 3 239472 113664267 0.220.0912 1.4747 0.6559 1 1 WCM341_Z2_1 3 113667680 131624150 −0.7761−1.4786 0.6983 0.0194 1 0 WCM341_Z2_1 3 131756412 197894719 0.24440.1235 1.4698 0.709 1 1 WCM341_Z2_1 4 59331 122687238 −0.4837 −0.94780.6828 0.354 1 0 WCM341_Z2_1 4 122687482 128996108 −0.1997 −0.499 1.0550.3603 1 0 WCM341_Z2_1 4 128999075 190426459 −0.4728 −0.9295 0.681 0.3691 0 WCM341_Z2_1 5 140532 180687812 −0.2629 −0.5945 0.9694 0.3551 1 0WCM341_Z2_1 6 203583 66014528 0.1134 −0.0524 1.288 0.6407 1 1WCM341_Z2_1 6 66042231 170892615 −0.0473 −0.2764 1.2871 0.3643 1 0WCM341_Z2_1 7 193205 158937161 0.5524 0.5183 1.5642 1.3003 2 1WCM341_Z2_1 8 190908 30510964 0.3667 0.2831 2.0087 0.4249 2 0WCM341_Z2_1 8 30537041 92088822 0.1887 0.0494 1.9913 0.0784 2 0WCM341_Z2_1 8 92090727 97307346 0.7705 0.7852 NA NA NA NA WCM341_Z2_1 897311955 146279481 0.1615 0.0128 1.9733 0.0445 2 0 WCM341_Z2_1 9 1705836170461 0.5139 0.4702 1.5885 1.1822 2 1 WCM341_Z2_1 9 36170642141111414 0.4121 0.3414 1.8965 0.6374 2 1 WCM341_Z2_1 X 2700148 654863780.2507 0.1318 NA NA NA NA WCM341_Z2_1 X 65819482 68725979 4.2131 4.4728NA NA NA NA WCM341_Z2_1 X 68748875 154509348 0.22 0.0912 NA NA NA NAWCM365 1 14930 16817454 −0.3978 0.0418 1.9956 0.0632 2 0 WCM365 116817690 17272777 −0.6134 −0.3473 1.449 0.1231 1 0 WCM365 1 17273325143391598 −0.4233 −0.0019 1.9634 0.0339 2 0 WCM365 1 143391861 1563511130.3119 1.1001 2.6485 1.639 3 2 WCM365 1 156351699 205538350 0.43571.2634 2.7069 2.0944 3 2 WCM365 1 205548875 225602998 0.3421 1.14052.2162 2.1928 2 2 WCM365 1 225605715 228873445 −0.1625 0.4223 2.6859−0.0058 3 0 WCM365 1 228879028 230933898 0.5168 1.3682 2.6112 2.5517 3 3WCM365 1 230972981 235491896 −0.2 0.3641 2.6185 −0.0443 3 0 WCM365 1235498675 249213464 0.523 1.3762 2.5957 2.5957 3 3 WCM365 10 22611835099886 −0.5124 −0.1591 1.7897 0.0015 2 0 WCM365 10 35103904 358969740.5731 1.4399 NA NA NA NA WCM365 10 35897346 65930362 0.2447 1.00952.0132 2.0132 2 2 WCM365 10 66473307 84625107 0.735 1.6421 4.171 2.07144 2 WCM365 10 84711187 89550252 −0.4238 −0.0028 2.0004 −0.0043 2 0WCM365 10 89552520 89728379 −1.8756 NA NA NA NA NA WCM365 10 90034829135477898 −0.413 0.0159 1.9828 0.0394 2 0 WCM365 11 193096 28930010.1509 0.8804 2.2564 1.4253 2 1 WCM365 11 2905000 36680581 0.0594 0.75131.6833 1.6833 2 2 WCM365 11 39882942 62286373 0.1896 0.9342 2.414 1.40752 1 WCM365 11 62286825 62652204 −0.1488 0.4433 NA NA NA NA WCM365 1162652779 66613043 0.1591 0.8919 1.8556 1.8556 2 2 WCM365 11 6661357568131420 0.9582 1.9124 5.5061 2.0229 6 2 WCM365 11 68133067 699971461.4475 2.4795 9.0365 2.1177 9 2 WCM365 11 69998546 71276632 1.13662.1228 6.5039 2.2067 7 2 WCM365 11 71276809 90602334 −0.0672 0.56661.889 1.0731 2 1 WCM365 11 92085375 107650507 0.1396 0.8647 1.821 1.8212 2 WCM365 11 107661831 109296234 −0.2182 0.3357 1.7744 0.7495 2 1WCM365 11 110001861 111431614 0.3328 1.1281 2.2089 2.1624 2 2 WCM365 11111473353 125525358 −0.4004 0.0375 1.9733 0.0793 2 0 WCM365 11 125542510134605853 −0.0099 0.6512 1.6646 1.4764 2 1 WCM365 12 148576 20903865−0.0874 0.5364 1.994 0.9067 2 1 WCM365 12 20905250 43887093 0.22580.9837 1.983 1.9722 2 2 WCM365 12 43895927 65641123 −0.0421 0.60381.5198 1.5198 2 2 WCM365 12 65641544 133733463 0.1823 0.924 1.93411.8607 2 2 WCM365 12 133758509 133810794 −0.0452 0.5993 NA NA NA NAWCM365 13 19042044 20660818 0.1325 0.8547 1.8616 1.7552 2 2 WCM365 1320715539 115089411 −0.3752 0.0802 2.0013 0.1131 2 0 WCM365 14 1911029738016880 0.1303 0.8517 2.4368 1.1724 2 1 WCM365 14 38019959 38680104−0.241 0.2996 NA NA NA NA WCM365 14 38680352 89154832 −0.421 0.00211.0014 1.0014 1 1 WCM365 14 89160728 97347512 −0.1357 0.4634 1.55971.198 2 1 WCM365 14 97410013 107283263 0.1927 0.9384 2.8141 1.0186 3 1WCM365 15 20083928 67008737 −0.1314 0.4699 1.9124 0.8578 2 1 WCM365 1567010033 69689748 −0.8674 −0.8829 1.1628 −0.0783 1 0 WCM365 15 69692440102506270 −0.0661 0.5683 1.891 1.0745 2 1 WCM365 16 64426 516805980.1383 0.8629 1.8187 1.8187 2 2 WCM365 16 52289317 90260461 −0.4357−0.0232 1.9406 0.0275 2 0 WCM365 17 131595 455063 0.3647 1.1704 NA NA NANA WCM365 17 456727 6900189 0.1641 0.8988 3.6507 0.0784 4 0 WCM365 176900362 10267863 −0.5209 −0.1746 1.7781 −0.006 2 0 WCM365 17 1029390825309007 0.1436 0.8702 1.8433 1.8126 2 2 WCM365 17 25621347 30821990−0.078 0.5506 1.6967 1.2327 2 1 WCM365 17 30921534 36093849 0.137 0.8611.9383 1.6944 2 2 WCM365 17 36099546 41180046 −0.0279 0.6247 1.54191.5419 2 2 WCM365 17 41180451 41296245 0.1477 0.876 NA NA NA NA WCM36517 41323203 42478819 −0.5168 −0.1672 1.8335 −0.0524 2 0 WCM365 1742483233 45886695 −0.1431 0.452 1.5667 1.1692 2 1 WCM365 17 4588809748918385 0.3738 1.1824 2.4791 2.06 2 2 WCM365 17 48939746 64001883−0.1269 0.4768 1.6519 1.1314 2 1 WCM365 17 64023624 73760724 0.16290.8972 1.8625 1.8625 2 2 WCM365 17 73761057 73805973 −0.9231 −1.0165 NANA NA NA WCM365 17 73806075 81187930 0.1535 0.884 1.8455 1.8455 2 2WCM365 18 47793 199244 0.2547 1.0231 NA NA NA NA WCM365 18 2030812674182 0.5629 1.4269 3.1222 2.2553 3 2 WCM365 18 2688513 3277944 1.05212.0238 NA NA NA NA WCM365 18 3447814 14147414 0.5877 1.4583 3.43192.0639 3 2 WCM365 18 14149969 24081139 0.1701 0.9071 1.9065 1.8441 2 2WCM365 18 24126753 67997305 −0.4097 0.0216 1.9995 0.0307 2 0 WCM365 1870204111 78005240 0.1266 0.8465 1.8359 1.7602 2 2 WCM365 19 1050213595522 −0.501 −0.1387 1.8013 0.0154 2 0 WCM365 19 3595794 40539980.3845 1.1965 2.4004 2.1833 2 2 WCM365 19 4054772 5592938 0.7179 1.6214.1703 1.9815 4 2 WCM365 19 5595369 10073478 0.3982 1.2145 2.5519 2.08913 2 WCM365 19 10077158 15752323 −0.112 0.4994 1.7685 1.0587 2 1 WCM36519 15752423 18499149 0.2144 0.9682 1.9564 1.9564 2 2 WCM365 19 1850283423542752 0.4159 1.2377 2.6079 2.1086 3 2 WCM365 19 23543100 391099750.1467 0.8746 1.8335 1.8335 2 2 WCM365 19 39111060 43262094 −0.507−0.1495 1.8055 −0.0023 2 0 WCM365 19 43262444 43544495 −1.6236 −5.2873NA NA NA NA WCM365 19 43568739 44896664 −0.4029 0.0332 2.014 0.0325 2 0WCM365 19 44901402 47030313 0.2977 1.0812 4.2769 −0.0454 4 0 WCM365 1947032047 50399231 0.0126 0.6839 3.2519 −0.0389 3 0 WCM365 19 5039933551430398 0.2421 1.006 3.8391 0.1776 4 0 WCM365 19 51430652 542656160.6193 1.4981 3.712 1.9375 4 2 WCM365 19 54291049 58437644 1.135 2.1216.5418 2.1579 7 2 WCM365 19 58437851 58992002 1.5873 2.6365 10.52271.914 11  2 WCM365 19 59009984 59093696 −0.2677 0.2569 NA NA NA NAWCM365 2 41583 84804515 −0.0343 0.6154 1.8004 1.2635 2 1 WCM365 284804548 88482514 0.3079 1.0947 2.2902 1.9813 2 2 WCM365 2 8848494597613616 −0.07 0.5625 1.5913 1.3624 2 1 WCM365 2 97617140 196619240−0.158 0.4293 1.5516 1.1416 2 1 WCM365 2 196620991 207395744 −0.03170.6191 1.9518 1.1201 2 1 WCM365 2 207406890 210010180 0.3133 1.10212.8902 1.4031 3 1 WCM365 2 210343638 243037004 −0.0273 0.6257 1.97141.1144 2 1 WCM365 20 68397 25667039 −0.4221  3.00E−04 1.9451 0.0553 2 0WCM365 20 25733312 47888117 0.235 0.9963 1.9949 1.9949 2 2 WCM365 2047892331 47905508 −0.9816 −1.1653 NA NA NA NA WCM365 20 4798870162934541 0.2712 1.0455 2.0641 2.0641 2 2 WCM365 21 9590305 39903442−0.3022 0.2012 1.1946 1.1047 1 1 WCM365 21 39906065 42870017 −0.7751−0.6759 1.2281 0.0238 1 0 WCM365 21 43133094 48084177 −0.2262 0.3231.2589 1.2431 1 1 WCM365 22 16159060 41734331 −0.4255 −0.0057 1.97660.0155 2 0 WCM365 22 41734486 42896725 −0.0976 0.5212 2.8947 −0.0245 3 0WCM365 22 42898736 51219089 −0.4112 0.0189 1.9739 0.0524 2 0 WCM365 3239524 85561088 −0.0884 0.535 1.8509 1.0469 2 1 WCM365 3 85757553118866376 0.0799 0.7806 1.7398 1.6959 2 2 WCM365 3 118867047 1977855150.1021 0.8119 2.3755 1.1356 2 1 WCM365 3 197785811 197896678 0.1310.8526 NA NA NA NA WCM365 4 53341 2438561 −0.0918 0.5298 2.9093 −0.02173 0 WCM365 4 2439900 2691258 0.013 0.6844 NA NA NA NA WCM365 4 269245421950259 0.1857 0.9288 2.7367 1.0706 3 1 WCM365 4 22389499 490637830.0348 0.7159 2.2342 1.0509 2 1 WCM365 4 49064001 49561719 −1.2987−2.2175 NA NA NA NA WCM365 4 49601562 54969875 0.0769 0.7763 NA NA NA NAWCM365 4 55125035 55606728 0.6479 1.534 NA NA NA NA WCM365 4 55946171190904468 0.0193 0.6936 2.2027 1.0319 2 1 WCM365 5 90784 181826 0.33741.1342 NA NA NA NA WCM365 5 182291 3599698 0.9204 1.8674 5.1704 2.1269 52 WCM365 5 3599857 52404485 0.3893 1.2028 2.3019 2.3019 2 2 WCM365 552404546 64538001 −0.3708 0.0876 1.0662 1.059 1 1 WCM365 5 6455648567593446 −0.0793 0.5486 1.8781 1.0471 2 1 WCM365 5 67593968 92919714−0.4203 0.0034 1.0024 1.0024 1 1 WCM365 5 92921032 96514921 −0.0970.5221 1.5246 1.3475 2 1 WCM365 5 96518765 131411722 −0.4121 0.01741.0122 1.0122 1 1 WCM365 5 131528316 133308560 −0.9314 −1.0371 1.0094−0.0348 1 0 WCM365 5 133309581 145872599 −0.3443 0.1319 1.1066 1.0848 11 WCM365 5 145878058 180687776 0.0485 0.7357 1.6699 1.6604 2 2 WCM365 6203546 22147301 −0.0165 0.6414 1.5987 1.521 2 2 WCM365 6 2228768526017582 0.2958 1.0786 2.112 2.112 2 2 WCM365 6 26017895 32139102 0.050.7378 1.8087 1.5265 2 2 WCM365 6 32146358 34835294 −0.411 0.0193 1.67380.3532 2 0 WCM365 6 34838640 57190745 −0.056 0.5832 1.896 1.1004 2 1WCM365 6 57244672 67859571 0.2333 0.994 2.3584 1.6251 2 2 WCM365 669345889 76624584 0.0119 0.6828 1.7264 1.4842 2 1 WCM365 6 7662563284935986 0.4609 1.2962 3.6514 1.2601 4 1 WCM365 6 85398259 170892873−0.1294 0.4731 1.3881 1.3881 1 1 WCM365 7 193222 933585 0.1209 0.83851.8635 1.7128 2 2 WCM365 7 935032 83758396 0.1955 0.9422 1.9214 1.9214 22 WCM365 7 83764092 158937161 0.114 0.8287 1.8061 1.7461 2 2 WCM365 8163470 35406923 −0.7423 −0.6061 1.3157 −0.0018 1 0 WCM365 8 3542569556652020 −0.2156 0.3397 2.5588 −0.0278 3 0 WCM365 8 56652748 907776090.4966 1.3423 2.7898 2.2813 3 2 WCM365 8 90782014 105601105 0.79341.7137 4.5013 2.0587 5 2 WCM365 8 106331156 125498283 0.5246 1.37812.935 2.2637 3 2 WCM365 8 125498510 132052217 0.9457 1.8976 5.15452.2975 5 2 WCM365 8 132052526 144621084 0.4981 1.3442 2.5814 2.4966 3 2WCM365 8 144621355 146279416 0.1303 0.8516 1.8349 1.7742 2 2 WCM365 9116924 9425617 −0.671 −0.4601 1.4685 −0.0146 1 0 WCM365 9 976688921482089 −0.2144 0.3417 2.4899 0.0445 2 0 WCM365 9 21512197 219676691.4355 2.4659 NA NA NA NA WCM365 9 21968126 22452130 −0.5336 −0.1977 NANA NA NA WCM365 9 23690357 34729468 1.0981 2.0778 5.3741 3.0693 5 3WCM365 9 34832762 38604943 0.6683 1.5595 2.9476 2.9476 3 3 WCM365 938607419 141107525 0.0514 0.7399 1.6701 1.6701 2 2 WCM365 X 270015644870323 0.1964 0.9435 NA NA NA NA WCM365 X 44879891 46584900 0.848 1.78NA NA NA NA WCM365 X 46696611 64628427 0.4003 1.2172 NA NA NA NA WCM365X 64708632 65835822 1.234 2.2358 NA NA NA NA WCM365 X 66765005 687489593.2585 4.4186 NA NA NA NA WCM365 X 68749585 154493598 0.1486 0.8773 NANA NA NA WCM365_Z2_1 1 721450 29651762 −0.569 0.0142 2.011 0.0088 2 0WCM365_Z2_1 1 29652118 32793189 −0.2981 0.3564 NA NA NA NA WCM365_Z2_1 132794689 120612034 −0.5851 −0.0066 1.9854 0.0054 2 0 WCM365_Z2_1 1144014068 225606973 0.4754 1.2633 2.8457 1.955 3 2 WCM365_Z2_1 1225609862 228786362 −0.1668 0.5168 2.8575 0.0039 3 0 WCM365_Z2_1 1228871682 230933950 1.2081 2.0658 NA NA NA NA WCM365_Z2_1 1 230937343235424048 −0.2235 0.4479 2.7674 −0.0393 3 0 WCM365_Z2_1 1 235498577235590541 1.0008 1.8425 NA NA NA NA WCM365_Z2_1 1 235594065 2419539291.2301 2.0893 5.8583 2.6523 6 3 WCM365_Z2_1 1 241958560 249212401 0.86131.6907 3.7818 2.6744 4 3 WCM365_Z2_1 10 255883 34985257 −0.6617 −0.1071.8612 −0.0042 2 0 WCM365_Z2_1 10 35103898 35930068 0.66 1.4692 NA NA NANA WCM365_Z2_1 10 35930331 49440168 0.1008 0.8345 1.8852 1.6812 2 2WCM365_Z2_1 10 49444555 54528022 0.335 1.1044 2.2651 2.0349 2 2WCM365_Z2_1 10 54528252 67829154 0.0883 0.8198 1.8333 1.697 2 2WCM365_Z2_1 10 67862924 84118519 0.5516 1.3486 3.0674 2.026 3 2WCM365_Z2_1 10 84498367 135440105 −0.5907 −0.0139 1.9766 0.0042 2 0WCM365_Z2_1 11 193146 107578641 0.2123 0.9638 1.9797 1.9212 2 2WCM365_Z2_1 11 107647302 111430956 −0.2405 0.4271 NA NA NA NAWCM365_Z2_1 11 111431184 125351473 −0.5496 0.0393 2.0396 0.0156 2 0WCM365_Z2_1 11 125359503 134241680 −0.1095 0.5857 1.9543 1.0473 2 1WCM365_Z2_1 11 134243650 134856603 0.0034 0.72 NA NA NA NA WCM365_Z2_112 148644 40715834 −0.1331 0.5573 1.9053 1.0378 2 1 WCM365_Z2_1 1240716260 49168253 −0.0369 0.6723 1.8547 1.3325 2 1 WCM365_Z2_1 1249168481 123035889 −0.1294 0.5618 1.9837 0.9685 2 1 WCM365_Z2_1 12123036236 133810935 0.1066 0.8412 2.6485 0.9345 3 1 WCM365_Z2_1 1319600515 80117742 −0.151 0.5358 1.9096 0.9899 2 1 WCM365_Z2_1 1380125186 115089411 −0.5973 −0.0226 1.9584 0.0105 2 0 WCM365_Z2_1 1419377692 23888815 0.1989 0.9484 1.952 1.9074 2 2 WCM365_Z2_1 14 23889048107283183 −0.1227 0.5699 1.9908 0.978 2 1 WCM365_Z2_1 15 2017004422489992 −0.8809 −0.4045 1.5735 −0.0626 2 0 WCM365_Z2_1 15 2283366465792946 −0.5863 −0.0082 1.9835 0.0052 2 0 WCM365_Z2_1 15 6580467866857697 −0.0904 0.6086 NA NA NA NA WCM365_Z2_1 15 66976341 69684016−1.2345 −0.9259 NA NA NA NA WCM365_Z2_1 15 69689537 102506276 −0.12890.5624 1.9615 0.9921 2 1 WCM365_Z2_1 16 67604 51185127 0.2365 0.99162.0067 1.9701 2 2 WCM365_Z2_1 16 52060303 90233297 −0.5822 −0.00291.9887 0.0073 2 0 WCM365_Z2_1 17 131595 6719251 0.3544 1.1264 4.36470.0016 4 0 WCM365_Z2_1 17 6722644 10267770 −0.4426 0.176 2.2711 −0.01162 0 WCM365_Z2_1 17 10293875 29902304 0.3285 1.0969 2.1926 2.0854 2 2WCM365_Z2_1 17 29902620 41277201 −0.0859 0.6139 1.9493 1.1116 2 1WCM365_Z2_1 17 41290786 42478676 −1.2331 −0.9237 1.0061 0.0482 1 0WCM365_Z2_1 17 42501781 49297776 −0.5807 −9.00E−04 1.0344 0.9644 1 1WCM365_Z2_1 17 49338241 59770797 −1.2554 −0.9587 1.0024 0.0266 1 0WCM365_Z2_1 17 59793382 63010673 −0.5706 0.0122 1.1457 0.8712 1 1WCM365_Z2_1 17 63049623 81083561 0.2496 1.0068 2.965 1.0539 3 1WCM365_Z2_1 18 48220 2674028 0.8911 1.7232 NA NA NA NA WCM365_Z2_1 182688626 3603996 1.5814 2.4624 NA NA NA NA WCM365_Z2_1 18 370847115006148 0.7621 1.582 3.8631 2.1246 4 2 WCM365_Z2_1 18 18531342 24081088−0.1336 0.5568 1.8337 1.1082 2 1 WCM365_Z2_1 18 24126843 70416282−0.5977 −0.0231 1.9617 0.0066 2 0 WCM365_Z2_1 18 70417525 73139433−0.1752 0.5065 1.9244 0.9169 2 1 WCM365_Z2_1 18 74074452 74980800 2.30293.2142 NA NA NA NA WCM365_Z2_1 18 76856549 78005199 −0.2696 0.3915 NA NANA NA WCM365_Z2_1 19 281508 3595923 −0.5379 0.0545 2.0842 −0.0072 2 0WCM365_Z2_1 19 3600000 4097323 0.257 1.0152 2.0746 1.9679 2 2WCM365_Z2_1 19 4099350 5262989 0.7544 1.5734 3.88 2.0723 4 2 WCM365_Z2_119 5265089 9971456 0.5304 1.3249 2.9314 2.079 3 2 WCM365_Z2_1 1910071227 36967452 −0.1161 0.5777 1.969 1.016 2 1 WCM365_Z2_1 19 3698064239218979 0.4979 1.2885 2.769 2.1165 3 2 WCM365_Z2_1 19 39219780 39989894−0.0862 0.6136 3.0681 −0.0079 3 0 WCM365_Z2_1 19 39991293 43269732−1.2455 −0.9432 1.0048 0.0354 1 0 WCM365_Z2_1 19 43341536 43530527−2.3115 −3.436 NA NA NA NA WCM365_Z2_1 19 43568732 43883177 −1.2802−0.9981 NA NA NA NA WCM365_Z2_1 19 43910667 51381789 −0.113 0.58152.9827 0.0101 3 0 WCM365_Z2_1 19 51385856 53383944 0.5054 1.297 2.98081.9336 3 2 WCM365_Z2_1 19 53384185 57640301 1.2757 2.138 6.8222 1.9809 72 WCM365_Z2_1 19 57640593 58806837 2.1821 3.0894 15.0401 1.9832 15  2WCM365_Z2_1 19 58846414 59083923 −0.54 0.0517 NA NA NA NA WCM365_Z2_1 241613 80529766 −0.1008 0.5962 1.948 1.0754 2 1 WCM365_Z2_1 2 8053002980773128 0.3849 1.1611 NA NA NA NA WCM365_Z2_1 2 80782965 971666140.2263 0.98 1.9974 1.9475 2 2 WCM365_Z2_1 2 97171003 155306936 0.47431.262 2.8056 1.9911 3 2 WCM365_Z2_1 2 155555473 242946604 −0.1593 0.52571.9786 0.9008 2 1 WCM365_Z2_1 20 68363 26188896 −0.6072 −0.0354 1.94560.0059 2 0 WCM365_Z2_1 20 29632632 62904848 0.2404 0.9962 2.0062 1.98322 2 WCM365_Z2_1 21 9907318 39822803 −0.1503 0.5366 1.8862 1.015 2 1WCM365_Z2_1 21 39947620 42870095 −0.6154 −0.0461 1.9975 −0.0605 2 0WCM365_Z2_1 21 43133055 48084277 −0.0958 0.6022 1.9485 1.0874 2 1WCM365_Z2_1 22 16287495 41676968 −0.5662 0.0178 2.0194 0.0055 2 0WCM365_Z2_1 22 41716687 42828268 −0.0652 0.6387 3.1156 −0.0018 3 0WCM365_Z2_1 22 42896695 51215152 −0.5661 0.018 2.017 0.0081 2 0WCM365_Z2_1 3 239350 71179680 −0.5562 0.0308 2.0342 0.0089 2 0WCM365_Z2_1 3 71247213 197894720 −0.1376 0.5519 1.9655 0.9666 2 1WCM365_Z2_1 4 59339 2464581 −0.5126 0.0869 2.1194 0.0048 2 0 WCM365_Z2_14 2498826 90874552 0.2958 1.0597 2.1178 2.0511 2 2 WCM365_Z2_1 491229611 93218685 −0.2963 0.3587 NA NA NA NA WCM365_Z2_1 4 93221978164533963 −0.1787 0.5023 1.8401 0.9928 2 1 WCM365_Z2_1 4 164534482190426502 −0.356 0.2847 1.4472 0.9891 1 1 WCM365_Z2_1 5 140644 52405546−0.0111 0.7029 1.9611 1.2945 2 1 WCM365_Z2_1 5 52778774 64625289 −0.616−0.047 1.0351 0.9008 1 1 WCM365_Z2_1 5 64747418 68411126 −0.1477 0.5397NA NA NA NA WCM365_Z2_1 5 68411965 131409786 −0.6148 −0.0453 0.98680.9513 1 1 WCM365_Z2_1 5 131410607 133304151 −1.2787 −0.9958 NA NA NA NAWCM365_Z2_1 5 133308513 143853561 −0.5751 0.0064 1.1673 0.8415 1 1WCM365_Z2_1 5 145176022 180687808 0.2061 0.9566 2.9284 0.9532 3 1WCM365_Z2_1 6 203552 367352 −0.1833 0.4968 NA NA NA NA WCM365_Z2_1 6393256 10557344 −1.2868 −1.0088 0.9561 0.0379 1 0 WCM365_Z2_1 6 1055753918572108 −0.183 0.4971 1.9227 0.9001 2 1 WCM365_Z2_1 6 19838198 255099251.1923 2.0488 6.4536 1.8219 6 2 WCM365_Z2_1 6 25510801 30782303 0.66851.4786 3.6323 1.9414 4 2 WCM365_Z2_1 6 30858815 32139228 0.2417 0.99772.107 1.8866 2 2 WCM365_Z2_1 6 32159158 32796751 −0.1903 0.4883 NA NA NANA WCM365_Z2_1 6 32800412 33756205 −0.554 0.0336 NA NA NA NA WCM365_Z2_16 33763331 36068017 −0.1319 0.5589 NA NA NA NA WCM365_Z2_1 6 3607535154254674 −0.5851 −0.0067 1.0407 0.9501 1 1 WCM365_Z2_1 6 5473531676751755 −0.1499 0.5371 1.8413 1.0609 2 1 WCM365_Z2_1 6 7678213884936092 0.4404 1.2238 3.6712 1 4 1 WCM365_Z2_1 6 85398382 170893424−0.1531 0.5333 1.9012 0.9933 2 1 WCM365_Z2_1 7 193222 71743764 0.19460.9434 1.943 1.903 2 2 WCM365_Z2_1 7 71868350 77045605 1.6884 2.57499.8504 2.0665 10  2 WCM365_Z2_1 7 77166921 158937046 0.2233 0.97652.0017 1.9337 2 2 WCM365_Z2_1 8 190900 32621527 −0.596 −0.0209 1.95020.0211 2 0 WCM365_Z2_1 8 33230198 56436496 0.2127 0.9643 3.8769 0.0253 40 WCM365_Z2_1 8 56656130 64099757 0.5648 1.3634 NA NA NA NA WCM365_Z2_18 64099940 113841912 1.0951 1.9443 5.6236 2.0735 6 2 WCM365_Z2_1 8113871381 144400207 1.2852 2.1482 5.7386 3.1268 6 3 WCM365_Z2_1 8144403485 146279481 0.556 1.3536 3.1235 1.9875 3 2 WCM365_Z2_1 9 1181138733796 −1.332 −1.0818 0.9567 −0.0118 1 0 WCM365_Z2_1 9 1269411421481664 −0.5857 −0.0074 1.991 −0.0012 2 0 WCM365_Z2_1 9 2151215021861975 1.9144 2.8113 NA NA NA NA WCM365_Z2_1 9 21931138 22451832−0.8298 −0.3337 NA NA NA NA WCM365_Z2_1 9 23692622 34723744 1.09471.9439 5.7465 1.9486 6 2 WCM365_Z2_1 9 34723935 43884984 0.5041 1.29552.9999 1.9095 3 2 WCM365_Z2_1 9 44870094 141111414 −0.1317 0.5591 1.92161.025 2 1 WCM365_Z2_1 X 2712619 44833908 −0.643 −0.0824 NA NA NA NAWCM365_Z2_1 X 44879891 51151372 1.7957 2.6874 NA NA NA NA WCM365_Z2_1 X51644748 65835798 0.7194 1.5349 NA NA NA NA WCM365_Z2_1 X 6676506067431965 5.5436 6.4959 NA NA NA NA WCM365_Z2_1 X 67454402 1545093480.1539 0.8963 NA NA NA NA WCM366 1 14930 249213961 0.0368 0.1832 1.13541.1354 1 1 WCM366 10 225979 135477891 0.0288 −0.0056 0.9961 0.9961 1 1WCM366 11 193112 134605916 0.0348 0.1386 1.2012 1.0004 1 1 WCM366 12148560 133810703 0.0173 −0.3263 0.7976 0.7976 1 1 WCM366 13 19041979115089411 0.022 −0.185 0.9543 0.805 1 1 WCM366 14 19110178 1072832690.0257 −0.084 0.9434 0.9434 1 1 WCM366 15 20083896 102506240 0.0410.2741 1.2093 1.2093 1 1 WCM366 16 64423 90260461 0.02 −0.2438 0.9190.77 1 1 WCM366 17 131595 81187906 0.0176 −0.3152 0.8038 0.8038 1 1WCM366 18 47610 78005135 0.0269 −0.0527 0.9641 0.9641 1 1 WCM366 19105080 59093696 −0.0334 NA −0.0579 −0.0579 0 0 WCM366 2 41463 2430527620.0164 −0.3539 0.7824 0.7824 1 1 WCM366 20 68299 62934617 0.0537 0.51811.4321 1.4321 1 1 WCM366 21 9590331 48084167 0.0275 −0.0388 1.04840.8986 1 1 WCM366 22 16159079 51219089 0.066 0.7224 1.6756 1.6243 2 2WCM366 3 239472 197896697 0.0288 −0.0048 0.9967 0.9967 1 1 WCM366 453334 190903980 0.0121 −0.4948 0.7097 0.7097 1 1 WCM366 5 90751180687861 0.0079 −0.6525 0.6362 0.6362 1 1 WCM366 6 203509 1708928480.0191 −0.2695 0.8296 0.8296 1 1 WCM366 7 193205 158937142 0.0103−0.5608 0.9247 0.4311 1 0 WCM366 8 163457 146279508 0.0215 −0.20040.8703 0.8703 1 1 WCM366 9 14822 141107582 0.0392 0.2359 1.1776 1.1776 11 WCM366 X 2700119 154509348 −0.0997 NA NA NA NA NA WCM366_X1_1 1 72147691447889 0.0667 −0.0108 0.9999 0.9853 1 1 WCM366_X1_1 1 9173164099470218 −0.4962 −0.9436 1.0607 −0.0209 1 0 WCM366_X1_1 1 99730124155018619 0.0644 −0.0142 1.0968 0.8836 1 1 WCM366_X1_1 1 155018860157811484 −0.5509 −1.0498 0.9608 0.0053 1 0 WCM366_X1_1 1 157963503249212244 0.0603 −0.0202 1.005 0.9672 1 1 WCM366_X1_1 10 255873 506034530.0721 −0.0028 1.0259 0.9701 1 1 WCM366_X1_1 10 50666859 88445446−0.5388 −1.026 0.9854 −0.0032 1 0 WCM366_X1_1 10 88446946 90537781−1.4777 −5.0095 NA NA NA NA WCM366_X1_1 10 90565762 135440108 −0.5127−0.9753 1.0031 0.0141 1 0 WCM366_X1_1 11 193112 134856563 0.0631 −0.0160.9992 0.9788 1 1 WCM366_X1_1 12 148675 133810703 0.0713 −0.0039 1.0090.9855 1 1 WCM366_X1_1 13 19600515 39622060 0.128 0.0787 1.0835 1.0286 11 WCM366_X1_1 13 39918139 109562474 −0.5388 −1.0261 1.0401 −0.058 1 0WCM366_X1_1 13 109610052 115089411 0.0812 0.0106 1.0458 0.969 1 1WCM366_X1_1 14 19377710 55655757 0.0479 −0.0386 0.9881 0.9592 1 1WCM366_X1_1 14 55817136 58678089 −0.5971 −1.1424 NA NA NA NA WCM366_X1_114 58680352 74083896 0.0625 −0.017 1.0218 0.9547 1 1 WCM366_X1_1 1474085999 93182528 −0.5276 −1.0042 0.9977 −6.00E−04  1 0 WCM366_X1_1 1493183771 107283203 0.0741  2.00E−04 1.0163 0.9839 1 1 WCM366_X1_1 1520169955 25496043 −0.4307 −0.8215 0.9939 0.1378 1 0 WCM366_X1_1 1525514932 102506276 0.0573 −0.0246 0.9991 0.9671 1 1 WCM366_X1_1 16 6695390161103 0.0769 0.0043 1.0148 0.9912 1 1 WCM366_X1_1 17 131595 54241980.0799 0.0086 1.0193 0.9927 1 1 WCM366_X1_1 17 5424989 8224276 −0.544−1.0361 1.0223 −0.0471 1 0 WCM366_X1_1 17 8243498 16351411 0.0876 0.01991.0451 0.9827 1 1 WCM366_X1_1 17 16365616 16665658 0.5029 0.5937 NA NANA NA WCM366_X1_1 17 16734836 17962196 0.053 −0.031 2.0151 −0.0575 2 0WCM366_X1_1 17 17965234 21191325 0.4549 0.5304 1.9575 0.9311 2 1WCM366_X1_1 17 21194843 31267828 0.057 −0.025 1.0468 0.9189 1 1WCM366_X1_1 17 31318958 34122377 −0.5313 −1.0114 0.9504 0.0417 1 0WCM366_X1_1 17 34182122 81083419 0.0745  8.00E−04 1.0123 0.9888 1 1WCM366_X1_1 18 48209 21492808 0.0687 −0.0078 1.0239 0.9653 1 1WCM366_X1_1 18 21494398 30351030 −0.5641 −1.0759 0.926 0.0227 1 0WCM366_X1_1 18 30353290 56587778 0.0598 −0.021 0.9929 0.9783 1 1WCM366_X1_1 18 56601821 78005214 −0.5358 −1.0201 1.0163 −0.0302 1 0WCM366_X1_1 19 281503 8212353 −0.523 −0.9953 0.9926 0.0107 1 0WCM366_X1_1 19 8316022 47551844 0.064 −0.0148 1.0073 0.9723 1 1WCM366_X1_1 19 47569690 48364615 −0.5442 −1.0367 NA NA NA NA WCM366_X1_119 48374796 59083968 0.0716 −0.0036 1.0107 0.9843 1 1 WCM366_X1_1 241623 242946607 0.0695 −0.0067 1.0042 0.9866 1 1 WCM366_X1_1 20 683736100088 −0.5292 −1.0072 1.0145 −0.0195 1 0 WCM366_X1_1 20 675090362384099 0.0664 −0.0112 1.0069 0.9777 1 1 WCM366_X1_1 20 6240710462904845 −0.5089 −0.968 1.0208 0.0017 1 0 WCM366_X1_1 21 990729739775468 0.0682 −0.0086 1.0277 0.9604 1 1 WCM366_X1_1 21 3979539842870081 −0.512 −0.974 0.9774 0.0408 1 0 WCM366_X1_1 21 4313307748084207 0.0737 −4.00E−04 1.0306 0.9688 1 1 WCM366_X1_1 22 1706348551215124 0.0709 −0.0046 1.0174 0.9763 1 1 WCM366_X1_1 3 239347 450773910.0816 0.0111 1.0181 0.9974 1 1 WCM366_X1_1 3 45127226 49828287 −0.5224−0.9941 1.0253 −0.0212 1 0 WCM366_X1_1 3 49828879 89521694 0.0658 −0.0121.0136 0.9698 1 1 WCM366_X1_1 3 89528644 102196386 −0.5023 −0.95530.9961 0.0354 1 0 WCM366_X1_1 3 105086318 137889032 0.064 −0.0147 1.02490.9548 1 1 WCM366_X1_1 3 137890526 139181115 0.5033 0.5943 NA NA NA NAWCM366_X1_1 3 139195237 189586486 0.0863 0.0181 1.0275 0.9978 1 1WCM366_X1_1 3 189587169 197894720 −0.5576 −1.063 0.9608 −0.0036 1 0WCM366_X1_1 4 59376 190426471 0.0714 −0.0038 1.0091 0.9856 1 1WCM366_X1_1 5 140526 180687800 0.0742  3.00E−04 1.0119 0.9884 1 1WCM366_X1_1 6 203535 72011510 0.0638 −0.015 1.0013 0.978 1 1 WCM366_X1_16 72086672 129465150 −0.2462 −0.4995 0.9888 0.4258 1 0 WCM366_X1_1 6129475727 170893415 0.0728 −0.0017 1.015 0.9827 1 1 WCM366_X1_1 7 193265158937400 0.0666 −0.0109 1.0042 0.9808 1 1 WCM366_X1_1 8 190906 9912088−0.5486 −1.0453 0.9755 −0.0064 1 0 WCM366_X1_1 8 10065365 10623169−1.4484 −4.5969 0.0649 0.0178 0 0 WCM366_X1_1 8 10645331 25902325 −0.521−0.9914 1.018 −0.012 1 0 WCM366_X1_1 8 26149344 27402010 −1.6289 NA NANA NA NA WCM366_X1_1 8 27455988 39525545 −0.4997 −0.9504 1.0303 0.0047 10 WCM366_X1_1 8 39534982 40683184 −1.596 NA NA NA NA NA WCM366_X1_1 841122763 67817527 −0.5399 −1.0281 1.0755 −0.0949 1 0 WCM366_X1_1 867831389 146279507 0.0668 −0.0106 0.9927 0.9927 1 1 WCM366_X1_1 9 17084916823 0.0539 −0.0297 NA NA NA NA WCM366_X1_1 9 968037 6255988 −0.5027−0.9561 1.0597 −0.0288 1 0 WCM366_X1_1 9 6328813 16020595 0.0467 −0.04031.0388 0.9061 1 1 WCM366_X1_1 9 16215239 19050060 −0.6584 −1.2704 NA NANA NA WCM366_X1_1 9 19050259 79635870 0.071 −0.0045 1.0233 0.9705 1 1WCM366_X1_1 9 79792635 89771644 −0.4696 −0.8935 NA NA NA NA WCM366_X1_19 90062823 113341692 0.0944 0.0298 1.0388 1.003 1 1 WCM366_X1_1 9113341804 119249760 −0.5307 −1.0102 0.9723 0.0207 1 0 WCM366_X1_1 9119380680 141111414 0.0792 0.0077 1.0186 0.9921 1 1 WCM366_X1_1 X2712639 154509348 0.0213 −0.0782 NA NA NA NA WCM369 1 14907 2492134200.0381 0.1251 1.0906 1.0906 1 1 WCM369 10 225982 135438959 0.0299 0.01331.0092 1.0092 1 1 WCM369 11 193096 62285788 0.0444 0.2053 1.1529 1.15291 1 WCM369 11 62285912 66099717 −0.0814 NA −0.0525 −0.0525 0 0 WCM369 1166100104 134605849 0.0378 0.1206 1.0872 1.0872 1 1 WCM369 12 148444133810886 0.0184 −0.1594 0.8954 0.8954 1 1 WCM369 13 19042044 1150894110.0269 −0.0298 0.9795 0.9795 1 1 WCM369 14 19110231 107283269 0.0231−0.0869 0.9415 0.9415 1 1 WCM369 15 20084061 102506264 0.0366 0.10461.0752 1.0752 1 1 WCM369 16 64400 90260461 0.0351 0.0842 1.0601 1.0601 11 WCM369 17 131595 81052609 0.0157 −0.2027 0.8689 0.8689 1 1 WCM369 1847790 78005160 0.0199 −0.1361 0.9099 0.9099 1 1 WCM369 19 10501059093696 −0.0018 −0.5189 0.6979 0.6979 1 1 WCM369 2 41662 2430370450.0126 −0.2545 0.8383 0.8383 1 1 WCM369 20 68446 62934541 0.0414 0.16821.1236 1.1236 1 1 WCM369 21 9590305 48084202 0.0115 −0.2719 0.82820.8282 1 1 WCM369 22 16158982 51219129 0.0615 0.4062 1.3252 1.3252 1 1WCM369 3 239436 197896818 0.022 −0.1028 0.9312 0.9312 1 1 WCM369 4 53336190878479 0.0215 −0.1108 0.9261 0.9261 1 1 WCM369 5 90680 1806878180.0104 −0.2912 0.8172 0.8172 1 1 WCM369 6 203374 170892848 0.0136−0.2367 0.8487 0.8487 1 1 WCM369 7 193245 158937161 0.0191 −0.1488 0.9020.902 1 1 WCM369 8 163432 146279472 0.0115 −0.2722 0.828 0.828 1 1WCM369 9 14859 141107519 0.0405 0.1567 1.1147 1.1147 1 1 WCM369 X2700202 154493585 −0.0845 NA NA NA NA NA WCM369_Z2_1 1 721415 930292340.0048 −0.0403 1.0157 0.9293 1 1 WCM369_Z2_1 1 93070905 120468032 −0.164−1.0132 0.9298 0.0612 1 0 WCM369_Z2_1 1 120468280 249212402 0.01770.0159 1.046 0.9762 1 1 WCM369_Z2_1 10 225979 108489811 −0.0068 −0.09280.9677 0.9077 1 1 WCM369_Z2_1 10 108536376 124713689 −0.1804 −1.14590.9345 −0.0307 1 0 WCM369_Z2_1 10 124740140 135440068 −0.0198 −0.15310.9375 0.8611 1 1 WCM369_Z2_1 11 193154 47862084 0.001 −0.0575 1.01260.9092 1 1 WCM369_Z2_1 11 47869483 63137597 −0.1618 −0.9962 1.0595−0.0568 1 0 WCM369_Z2_1 11 63137897 134856597 0.005 −0.0393 1.00770.9385 1 1 WCM369_Z2_1 12 148637 46325313 0.018 0.0174 1.0906 0.9337 1 1WCM369_Z2_1 12 46339070 56120500 0.182 0.62 1.6541 1.4196 2 1WCM369_Z2_1 12 56120950 72893328 0.4489 1.339 2.6533 2.4064 3 2WCM369_Z2_1 12 72936128 110969446 0.1431 0.4926 3.0807 −0.2667 3 0WCM369_Z2_1 12 110974890 133683077 0.3172 1.0121 2.9557 1.078 3 1WCM369_Z2_1 12 133696900 133810703 0.1838 0.6257 NA NA NA NA WCM369_Z2_113 19600159 36767768 −0.0327 −0.2151 0.9625 0.7605 1 1 WCM369_Z2_1 1336776080 73637987 −0.1838 −1.175 0.8712 0.0145 1 0 WCM369_Z2_1 1373649988 115089411 0.0037 −0.0454 1.0208 0.9172 1 1 WCM369_Z2_1 1419377710 107283034 0.0152 0.0053 1.0602 0.9471 1 1 WCM369_Z2_1 1520169971 102506273 0.0153 0.0055 1.3346 0.6731 1 1 WCM369_Z2_1 16 6760457953115 0.0331 0.0814 1.1198 0.9964 1 1 WCM369_Z2_1 16 5795430289620186 0.0315 0.0747 2.0609 0.0453 2 0 WCM369_Z2_1 16 8962093390162178 0.0378 0.1006 2.2302 −0.0858 2 0 WCM369_Z2_1 17 131595 17079880.0291 0.0646 1.0458 1.0458 1 1 WCM369_Z2_1 17 1715316 17991379 −0.1635−1.0093 1.0043 −0.0107 1 0 WCM369_Z2_1 17 17997248 81083419 0.027 0.05591.0878 0.9912 1 1 WCM369_Z2_1 18 48206 18547017 −0.0035 −0.0776 1.03780.8574 1 1 WCM369_Z2_1 18 18547759 44683862 0.1889 0.6419 1.7272 1.39352 1 WCM369_Z2_1 18 44693042 78005215 −0.1784 −1.1293 1.0317 −0.1174 1 0WCM369_Z2_1 19 281405 373513 −0.2561 −1.9559 NA NA NA NA WCM369_Z2_1 19374344 9268741 −0.1678 −1.0434 0.9835 −0.0131 1 0 WCM369_Z2_1 19 926958059083953 0.0117 −0.0099 1.0236 0.9628 1 1 WCM369_Z2_1 2 41623 249732−0.2823 −2.3754 NA NA NA NA WCM369_Z2_1 2 253112 219221890 0.009 −0.02171.0284 0.9417 1 1 WCM369_Z2_1 2 219222400 242946597 −0.1501 −0.90920.9826 0.0824 1 0 WCM369_Z2_1 20 68397 62904848 0.0188 0.0206 1.04060.9882 1 1 WCM369_Z2_1 21 9907318 48084210 −0.0319 −0.2114 0.9479 0.77951 1 WCM369_Z2_1 22 17060362 20044100 0.0633 0.2032 1.2907 1.0118 1 1WCM369_Z2_1 22 20044324 29932632 −0.1783 −1.1286 0.9787 −0.0639 1 0WCM369_Z2_1 22 29935409 43565703 0.0238 0.0421 1.1303 0.929 1 1WCM369_Z2_1 22 43565855 51215134 −0.1695 −1.0569 0.9133 0.048 1 0WCM369_Z2_1 3 239459 45715028 0.02 0.0257 1.0485 0.9874 1 1 WCM369_Z2_13 45715850 97503819 −0.1209 −0.7087 0.6673 0.5564 1 1 WCM369_Z2_1 397506924 132179158 0.0082 −0.0253 1.0086 0.9566 1 1 WCM369_Z2_1 3132179936 197894726 0.1542 0.5299 1.5396 1.348 2 1 WCM369_Z2_1 4 59434190426502 −0.0221 −0.1638 0.9393 0.846 1 1 WCM369_Z2_1 5 140657 52856504−0.0289 −0.1967 0.9148 0.8303 1 1 WCM369_Z2_1 5 52900714 74026175−0.2012 −1.3305 0.7684 0.0268 1 0 WCM369_Z2_1 5 74032597 180687812−0.0047 −0.083 0.9956 0.8926 1 1 WCM369_Z2_1 6 203510 170893407 −0.029−0.1972 0.9271 0.8174 1 1 WCM369_Z2_1 7 193222 158937375 0 −0.06180.9925 0.9236 1 1 WCM369_Z2_1 8 190907 17851057 0.0234 0.0405 1.21230.8447 1 1 WCM369_Z2_1 8 17863777 28827860 −0.1999 −1.3183 0.8059−0.0039 1 0 WCM369_Z2_1 8 28828030 146279508 −3.00E−04 −0.0634 1.02160.8924 1 1 WCM369_Z2_1 9 17083 141111414 −0.1918 −1.2445 1.0478 −0.20381 0 WCM369_Z2_1 X 2707688 2835964 0.1385 0.477 NA NA NA NA WCM369_Z2_1 X2836181 57934478 0.2665 0.8731 NA NA NA NA WCM369_Z2_1 X 5793542268060181 1.7467 3.4728 NA NA NA NA WCM369_Z2_1 X 68381640 154509348−0.0324 −0.2137 NA NA NA NA WCM4 1 14930 6160087 0.1301 NA NA NA NA NAWCM4 1 6161939 115400167 −0.1131 NA NA NA NA NA WCM4 1 115401180249213973 0.0886 NA NA NA NA NA WCM4 10 226116 42833224 −0.0794 NA NA NANA NA WCM4 10 42833380 88935651 0.0388 NA NA NA NA NA WCM4 10 88939943135477904 −0.096 NA NA NA NA NA WCM4 11 193062 47435995 −0.0247 NA NA NANA NA WCM4 11 47436351 75277858 −0.1362 NA NA NA NA NA WCM4 11 75279846134605954 0.0409 NA NA NA NA NA WCM4 12 148474 133810704 0.0289 NA NA NANA NA WCM4 13 19041994 115089411 −0.1285 NA NA NA NA NA WCM4 14 19110239107283263 0.0085 NA NA NA NA NA WCM4 15 20083910 102514200 −0.0356 NA NANA NA NA WCM4 16 64400 28992738 0.0524 NA NA NA NA NA WCM4 16 2899292490110967 −0.1169 NA NA NA NA NA WCM4 16 90113379 90260461 −0.0013 NA NANA NA NA WCM4 17 131595 15449101 −0.1304 NA NA NA NA NA WCM4 17 1545700080918962 −0.0071 NA NA NA NA NA WCM4 17 80923643 81187925 −0.4072 NA NANA NA NA WCM4 18 47725 78005199 −0.1024 NA NA NA NA NA WCM4 19 10502159093645 −0.0188 NA NA NA NA NA WCM4 2 41686 98744672 −0.1316 NA NA NANA NA WCM4 2 98750402 212295835 0.0037 NA NA NA NA NA WCM4 2 212295875243036990 −0.1127 NA NA NA NA NA WCM4 20 68413 62934592 0.0731 NA NA NANA NA WCM4 21 9590312 48084175 0.0154 NA NA NA NA NA WCM4 22 1615904451219090 −0.0573 NA NA NA NA NA WCM4 3 239495 134644799 0.0186 NA NA NANA NA WCM4 3 134652841 197896714 0.2308 NA NA NA NA NA WCM4 4 53345515522 −0.1528 NA NA NA NA NA WCM4 4 515682 77941804 −0.0128 NA NA NA NANA WCM4 4 77949963 190878508 −0.1558 NA NA NA NA NA WCM4 5 90750180687818 −0.0113 NA NA NA NA NA WCM4 6 203515 67069109 −0.0134 NA NA NANA NA WCM4 6 67859579 100957844 −0.1758 NA NA NA NA NA WCM4 6 100960563170892848 −0.0126 NA NA NA NA NA WCM4 7 193205 158937135 0.0066 NA NA NANA NA WCM4 8 163438 62366826 −0.0635 NA NA NA NA NA WCM4 8 62371063144621438 0.2659 NA NA NA NA NA WCM4 8 144623550 146279472 0.0303 NA NANA NA NA WCM4 9 14878 20995821 −0.1395 NA NA NA NA NA WCM4 9 21007152141107513 0.0419 NA NA NA NA NA WCM4 X 2700194 154493598 −0.0226 NA NANA NA NA WCM4_X1_1 1 721476 5624154 0.1793 1.2493 2.5103 2.2442 3 2WCM4_X1_1 1 5716339 114634694 −0.2199 0.0526 2.025 0.0492 2 0 WCM4_X1_11 114636419 117509908 0.0705 0.9813 2.4369 1.5115 2 2 WCM4_X1_1 1117516944 145115820 0.327 1.5728 4.762 1.1876 5 1 WCM4_X1_1 1 145209397160012078 0.0918 1.0361 2.8855 1.2159 3 1 WCM4_X1_1 1 160012313201176977 0.1963 1.2886 3.9462 0.9395 4 1 WCM4_X1_1 1 201177033249212393 0.2893 1.4938 3.7257 1.9069 4 2 WCM4_X1_1 10 225958 42907265−0.1018 0.4808 1.8973 0.8937 2 1 WCM4_X1_1 10 42916247 88973968 0.09051.0328 2.1294 1.9626 2 2 WCM4_X1_1 10 88975814 108924259 −0.2391 −0.0271.9521 0.0108 2 0 WCM4_X1_1 10 111625035 125805389 −0.07 0.5824 1.64191.3528 2 1 WCM4_X1_1 10 125805631 135440108 −0.2105 0.0902 1.9826 0.14632 0 WCM4_X1_1 11 193112 211203 0.011 0.8209 NA NA NA NA WCM4_X1_1 11212483 280464 −0.1155 0.4357 NA NA NA NA WCM4_X1_1 11 280767 48387559−0.0509 0.6412 2.1976 0.9216 2 1 WCM4_X1_1 11 48387833 67200098 −0.20740.1026 1.8794 0.268 2 0 WCM4_X1_1 11 67200513 75298409 −0.0739 0.572.9776 −0.0085 3 0 WCM4_X1_1 11 75298797 75851965 −0.1463 0.3301 NA NANA NA WCM4_X1_1 11 75852095 134856592 0.1753 1.2399 2.478 2.2458 2 2WCM4_X1_1 12 148811 10870701 0.3412 1.6018 4.0586 2.012 4 2 WCM4_X1_1 1210871730 27470922 0.2032 1.3042 2.6048 2.3342 3 2 WCM4_X1_1 12 2747228250291309 0.0549 0.9404 2.031 1.8072 2 2 WCM4_X1_1 12 50291799 133779971−0.0676 0.5898 1.9208 1.0892 2 1 WCM4_X1_1 12 133780228 133810735 0.16091.2058 NA NA NA NA WCM4_X1_1 13 19600515 31729729 0.0585 0.9499 1.98271.8807 2 2 WCM4_X1_1 13 31732966 115089411 −0.2362 −0.0149 1.9623 0.01712 0 WCM4_X1_1 14 19377711 55411144 0.0581 0.9489 1.9559 1.9049 2 2WCM4_X1_1 14 55422341 72932528 −0.1035 0.4755 1.7321 1.0486 2 1WCM4_X1_1 14 72936731 107283039 0.0666 0.9712 2.0066 1.9143 2 2WCM4_X1_1 15 20169960 30337272 −0.3626 −0.6413 1.437 −0.1547 1 0WCM4_X1_1 15 30384259 42162092 0.0457 0.9159 2.8469 0.9266 3 1 WCM4_X1_115 42162683 53997323 −0.0889 0.5226 1.5562 1.3169 2 1 WCM4_X1_1 1553998178 72050344 −0.209 0.096 1.899 0.2387 2 0 WCM4_X1_1 15 7205736872454350 −0.1687 0.2495 NA NA NA NA WCM4_X1_1 15 72454688 79586159−0.0629 0.6045 1.6938 1.347 2 1 WCM4_X1_1 15 79586361 102517678 −0.21390.0766 1.0883 1.0208 1 1 WCM4_X1_1 16 66926 48582018 0.0868 1.02342.0742 1.991 2 2 WCM4_X1_1 16 48585330 90233642 −0.2066 0.1057 2.03910.1129 2 0 WCM4_X1_1 17 131595 4458164 −0.0475 0.6514 2.954 0.1874 3 0WCM4_X1_1 17 4458515 15341453 −0.2231 0.0396 2.0051 0.0505 2 0 WCM4_X1_117 15343552 76554194 −0.0548 0.6291 2.0839 1.0093 2 1 WCM4_X1_1 1776556956 81083561 0.0981 1.0523 2.1681 1.9795 2 2 WCM4_X1_1 18 48245254318 −0.1582 0.2877 NA NA NA NA WCM4_X1_1 18 259240 23866185 −0.03270.6956 1.701 1.5382 2 2 WCM4_X1_1 18 23866440 78005226 −0.2385 −0.02451.9791 −0.0128 2 0 WCM4_X1_1 19 281439 24309994 −0.0509 0.641 2.14070.9781 2 1 WCM4_X1_1 19 24310193 59083953 0.0624 0.9602 1.9762 1.9149 22 WCM4_X1_1 2 41613 54587381 −0.2267 0.0245 1.8916 0.1427 2 0 WCM4_X1_12 54587596 68280249 −0.0047 0.7768 2.543 0.8838 3 1 WCM4_X1_1 2 6835247596859079 −0.1981 0.139 2.0144 0.1878 2 0 WCM4_X1_1 2 96860719 99136591−0.019 0.7357 NA NA NA NA WCM4_X1_1 2 99137194 116572392 0.1848 1.2623.5724 1.224 4 1 WCM4_X1_1 2 116573271 186610166 0.0373 0.8932 3.7965−0.082 4 0 WCM4_X1_1 2 186611497 187713816 −0.3782 −0.7367 NA NA NA NAWCM4_X1_1 2 188211116 189839262 −0.2186 0.0578 NA NA NA NA WCM4_X1_1 2189849556 213790998 −0.0849 0.5353 2.9078 −0.0094 3 0 WCM4_X1_1 2213872233 232894702 −0.2213 0.0468 1.9821 0.0839 2 0 WCM4_X1_1 2232952213 242946616 −0.3799 −0.7472 1.2053 −0.0137 1 0 WCM4_X1_1 2068396 30115358 0.188 1.2693 3.8158 1.005 4 1 WCM4_X1_1 20 3012612262904848 0.0906 1.0332 3.9649 0.1281 4 0 WCM4_X1_1 21 9826207 163402890.3148 1.5473 5.5291 0.3165 6 0 WCM4_X1_1 21 16340513 41137780 −0.10090.4839 1.855 0.942 2 1 WCM4_X1_1 21 41142950 48084207 0.0719 0.985 2.1441.8147 2 2 WCM4_X1_1 22 16287439 17443751 0.0854 1.0199 NA NA NA NAWCM4_X1_1 22 17444668 24086864 0.0745 0.9918 2.133 1.8443 2 2 WCM4_X1_122 24087185 51215124 −0.2025 0.1216 2.1133 0.0626 2 0 WCM4_X1_1 3 239390121303785 −0.0633 0.6033 2.0065 1.0318 2 1 WCM4_X1_1 3 121304902123550262 0.1949 1.2852 3.7933 1.081 4 1 WCM4_X1_1 3 123616390 134977951−0.0833 0.5406 1.5655 1.3437 2 1 WCM4_X1_1 3 135720431 197894726 0.47941.8714 5.3857 1.932 5 2 WCM4_X1_1 4 59376 338183 −0.0823 0.5436 NA NA NANA WCM4_X1_1 4 343982 77676328 0.0753 0.9938 2.0224 1.9605 2 2 WCM4_X1_14 77677694 190426459 −0.2501 −0.0742 1.9543 −0.0546 2 0 WCM4_X1_1 5140608 9063206 0.4565 1.8284 4.304 2.7991 4 3 WCM4_X1_1 5 906664845645434 0.1661 1.2182 2.7881 1.8652 3 2 WCM4_X1_1 5 45695803 180687766−0.0831 0.5413 1.8897 1.0208 2 1 WCM4_X1_1 6 203624 395927 0.0394 0.899NA NA NA NA WCM4_X1_1 6 397251 33140341 −0.089 0.5224 1.8138 1.0589 2 1WCM4_X1_1 6 33141291 66205190 0.0677 0.9741 1.9645 1.9645 2 2 WCM4_X1_16 68598968 107389972 −0.2472 −0.0617 1.8656 0.0507 2 0 WCM4_X1_1 6107390452 108370490 −0.0208 0.7304 NA NA NA NA WCM4_X1_1 6 108372400158735083 0.0594 0.9523 1.9911 1.8788 2 2 WCM4_X1_1 6 158834126170893406 −0.0701 0.582 2.0658 0.9279 2 1 WCM4_X1_1 7 193245 11415429−0.0567 0.6233 1.9546 1.1262 2 1 WCM4_X1_1 7 11416258 90675228 0.10081.0589 2.1359 2.0309 2 2 WCM4_X1_1 7 90708790 95664996 0.3872 1.69434.7218 1.7508 5 2 WCM4_X1_1 7 95668664 100674493 0.0857 1.0206 2.461.5975 2 2 WCM4_X1_1 7 100674969 158937074 −0.063 0.6042 2.0169 1.0233 21 WCM4_X1_1 8 190897 17270785 0.0605 0.9551 2.0358 1.8418 2 2 WCM4_X1_18 17396380 38028519 −0.2298 0.0121 1.9812 0.0356 2 0 WCM4_X1_1 838029513 61765560 0.0321 0.8792 1.9895 1.6892 2 2 WCM4_X1_1 8 6176594465527696 0.3593 1.6386 NA NA NA NA WCM4_X1_1 8 65528414 141449204 0.57952.0528 6.3147 1.9837 6 2 WCM4_X1_1 8 141461185 143999086 0.4292 1.77644.441 2.4105 4 2 WCM4_X1_1 8 144063784 146279507 0.1039 1.0667 2.09472.0947 2 2 WCM4_X1_1 9 17066 21409188 −0.1418 0.3458 2.5134 0.0284 3 0WCM4_X1_1 9 21409656 141006951 0.0671 0.9726 2.0085 1.9162 2 2 WCM4_X1_19 141008884 141111414 −0.1567 0.2932 NA NA NA NA WCM4_X1_1 X 27001256069337 0.4826 1.8773 NA NA NA NA WCM4_X1_1 X 6301987 64137723 0.04220.9066 NA NA NA NA WCM4_X1_1 X 64138973 67273525 0.711 2.2772 NA NA NANA WCM4_X1_1 X 67283750 154509348 0.0233 0.8552 NA NA NA NA WCM6 1 174681635601 0.0695 NA NA NA NA NA WCM6 1 1644760 83451726 −0.035 NA NA NA NANA WCM6 1 83568637 86907151 0.0049 NA NA NA NA NA WCM6 1 86909567145290346 0.0037 NA NA NA NA NA WCM6 1 145293515 249213973 −0.0046 NA NANA NA NA WCM6 10 226107 26355872 −0.0325 NA NA NA NA NA WCM6 10 2635762535320431 −0.0181 NA NA NA NA NA WCM6 10 35321414 135438976 −0.0199 NA NANA NA NA WCM6 11 193096 134605610 −0.0463 NA NA NA NA NA WCM6 12 14844472288678 −0.0531 NA NA NA NA NA WCM6 12 72289843 105568239 −0.0589 NA NANA NA NA WCM6 12 105569748 133810794 −0.0687 NA NA NA NA NA WCM6 1319041992 115070216 −0.0442 NA NA NA NA NA WCM6 14 19110297 107283263−0.0482 NA NA NA NA NA WCM6 15 20083928 102506284 −0.0279 NA NA NA NA NAWCM6 16 67688 90260461 −0.0528 NA NA NA NA NA WCM6 17 131595 81187935−0.0473 NA NA NA NA NA WCM6 18 47823 78005135 −0.05 NA NA NA NA NA WCM619 105021 59093533 −0.0412 NA NA NA NA NA WCM6 2 41614 243037022 −0.0358NA NA NA NA NA WCM6 20 68413 62934572 −0.0542 NA NA NA NA NA WCM6 219590301 48084211 −0.0267 NA NA NA NA NA WCM6 22 16159021 51215098−0.0693 NA NA NA NA NA WCM6 3 361557 197894726 −0.0154 NA NA NA NA NAWCM6 4 53379 190874234 −0.0123 NA NA NA NA NA WCM6 5 90697 180687824−0.0351 NA NA NA NA NA WCM6 6 203397 13601066 −0.0438 NA NA NA NA NAWCM6 6 13604710 34950511 −0.0703 NA NA NA NA NA WCM6 6 34951233170892883 −0.0386 NA NA NA NA NA WCM6 7 193222 158937072 −0.0422 NA NANA NA NA WCM6 8 163474 146279349 −0.002 NA NA NA NA NA WCM6 9 116841141107533 −0.0089 NA NA NA NA NA WCM6 X 2700194 154493484 −0.1863 NA NANA NA NA WCM63 1 14907 249213206 0.0131 0.1289 1.0935 1.0935 1 1 WCM6310 225988 135438960 −0.0101 −0.021 0.9856 0.9856 1 1 WCM63 11 193096134605906 −0.0186 −0.0794 0.9464 0.9464 1 1 WCM63 12 148567 133810712−2.00E−04 0.0448 1.0315 1.0315 1 1 WCM63 13 19041979 115089411 −0.0753−0.5315 0.6919 0.6919 1 1 WCM63 14 19110343 107283274 −0.0036 0.02231.0156 1.0156 1 1 WCM63 15 20083905 102513459 −0.0343 −0.1923 0.87520.8752 1 1 WCM63 16 66881 310757 −0.1359 −1.2176 0.8263 0.0337 1 0 WCM6316 311469 50134196 0.0548 0.3695 1.2919 1.2919 1 1 WCM63 16 5013433490168697 −0.0833 −0.6065 0.6568 0.6568 1 1 WCM63 17 131595 811879350.0021 0.0596 1.0422 1.0422 1 1 WCM63 18 47654 78005150 −0.0078 −0.00540.9963 0.9963 1 1 WCM63 19 105069 59093696 −0.0521 −0.3314 0.7948 0.79481 1 WCM63 2 41602 243037003 −0.0181 −0.0759 0.9488 0.9488 1 1 WCM63 2068346 62934541 0.0145 0.1378 1.1003 1.1003 1 1 WCM63 21 9590314 48084170−0.0025 0.0295 1.0206 1.0206 1 1 WCM63 22 16159068 51219089 0.00750.0943 1.0675 1.0675 1 1 WCM63 3 239524 197896800 0.055 0.3706 1.29281.2928 1 1 WCM63 4 53364 52729266 0.0212 0.1781 1.1314 1.1314 1 1 WCM634 52729812 82366788 0.2959 1.3546 2.6477 2.4668 3 2 WCM63 4 82366976190878479 −0.0136 −0.0447 0.9695 0.9695 1 1 WCM63 5 90784 443104920.0703 0.4512 1.3672 1.3672 1 1 WCM63 5 44388482 140866319 −0.0876−0.6492 0.6376 0.6376 1 1 WCM63 5 140866565 180687776 0.0175 0.15621.1144 1.1144 1 1 WCM63 6 203475 170892918 −0.0226 −0.1076 0.9281 0.92811 1 WCM63 7 193265 158937022 0.0452 0.317 1.2458 1.2458 1 1 WCM63 8163432 37607152 −0.1036 −0.8149 0.6121 0.5248 1 1 WCM63 8 37607377146003567 0.1243 0.7093 1.635 1.635 2 2 WCM63 8 146005648 146279416−0.175 −1.9032 NA NA NA NA WCM63 9 116804 141107525 0.0128 0.1271 1.09211.0921 1 1 WCM63 X 2700141 154493590 −0.2258 −4.0144 NA NA NA NAWCM63_X1_1 1 69603 11169379 0.0999 NA NA NA NA NA WCM63_X1_1 1 1116977643315345 −0.0839 NA NA NA NA NA WCM63_X1_1 1 43316408 174606535 0.1084NA NA NA NA NA WCM63_X1_1 1 174652731 249212550 −0.0447 NA NA NA NA NAWCM63_X1_1 10 226021 135440086 −0.0495 NA NA NA NA NA WCM63_X1_1 11193146 134856523 −0.0543 NA NA NA NA NA WCM63_X1_1 12 148644 133810703−0.0561 NA NA NA NA NA WCM63_X1_1 13 19600515 115089411 0.027 NA NA NANA NA WCM63_X1_1 14 19377726 107283210 0.1078 NA NA NA NA NA WCM63_X1_115 20170150 102517660 0.0854 NA NA NA NA NA WCM63_X1_1 16 66953 901621660.0955 NA NA NA NA NA WCM63_X1_1 17 131595 81083507 0.1009 NA NA NA NANA WCM63_X1_1 18 48236 78005215 0.0916 NA NA NA NA NA WCM63_X1_1 19281535 59083953 0.0623 NA NA NA NA NA WCM63_X1_1 2 41612 2429466070.0916 NA NA NA NA NA WCM63_X1_1 20 68363 62904932 0.0883 NA NA NA NA NAWCM63_X1_1 21 9907319 48084282 0.1182 NA NA NA NA NA WCM63_X1_1 2216287491 51215107 0.074 NA NA NA NA NA WCM63_X1_1 3 239347 1978947200.1278 NA NA NA NA NA WCM63_X1_1 4 59327 190426502 −0.0175 NA NA NA NANA WCM63_X1_1 5 140532 180687768 −0.0564 NA NA NA NA NA WCM63_X1_1 6203577 170893389 −0.0536 NA NA NA NA NA WCM63_X1_1 7 193436 158937416−0.0506 NA NA NA NA NA WCM63_X1_1 8 190897 146279434 −0.0324 NA NA NA NANA WCM63_X1_1 9 116846 141111414 −0.0704 NA NA NA NA NA WCM63_X1_1 X2707709 154509348 −0.1085 NA NA NA NA NA WCM63_Z1_1 1 69569 119444015−0.5313 −0.0115 1.0108 0.9733 1 1 WCM63_Z1_1 1 119466151 1876108710.1372 0.7158 2.3052 0.9795 2 1 WCM63_Z1_1 1 190067283 202532025 −0.5489−0.031 1.0005 0.9569 1 1 WCM63_Z1_1 1 202533582 214209028 −0.0092 0.55891.9833 0.963 2 1 WCM63_Z1_1 1 214454687 249212420 −0.5702 −0.0548 0.97780.9477 1 1 WCM63_Z1_1 10 226016 135440081 −0.5616 −0.0452 0.9778 0.96051 1 WCM63_Z1_1 11 193127 43419010 −0.4779 0.0479 1.1207 0.9467 1 1WCM63_Z1_1 11 43419535 48286316 −0.0803 0.4823 2.8115 −0.0176 3 0WCM63_Z1_1 11 48327935 65625613 0.3382 0.9294 2.7672 1.0418 3 1WCM63_Z1_1 11 65625903 71139887 0.6443 1.2515 2.847 1.9149 3 2WCM63_Z1_1 11 71146195 107300116 0.3379 0.9291 2.7968 1.0114 3 1WCM63_Z1_1 11 107304401 126969232 −0.1717 0.3834 2.618 −0.0092 3 0WCM63_Z1_1 11 128332391 134856563 0.6312 1.2378 2.4522 2.2645 2 2WCM63_Z1_1 12 148642 45108506 0.555 1.1578 2.6224 1.8401 3 2 WCM63_Z1_112 45168521 133810703 −0.0332 0.5331 1.9285 0.9656 2 1 WCM63_Z1_1 1319600515 30854220 −0.3051 0.2381 1.6879 0.6709 2 1 WCM63_Z1_1 1330857848 88329795 −0.7767 −0.2872 1.6524 −0.0134 2 0 WCM63_Z1_1 1388329996 115089411 −0.3603 0.1775 1.6488 0.613 2 1 WCM63_Z1_1 1419377710 39787206 0.0238 0.5944 2.0026 1.0171 2 1 WCM63_Z1_1 14 3978841764009521 0.3376 0.9287 1.9238 1.8835 2 2 WCM63_Z1_1 14 64065707 94510964−0.4862 0.0386 2.0572 −0.003 2 0 WCM63_Z1_1 14 94512109 107283027 0.04330.6153 2.0494 1.0143 2 1 WCM63_Z1_1 15 20170150 102517667 −0.5243−0.0036 1.0696 0.9254 1 1 WCM63_Z1_1 16 66926 50245357 0.5427 1.1453.4563 0.9666 3 1 WCM63_Z1_1 16 50250068 53738108 −0.4434 0.086 1.20450.9184 1 1 WCM63_Z1_1 16 53844066 67919945 −1.3215 −0.9245 1.0564−0.0027 1 0 WCM63_Z1_1 16 67942698 68849468 −0.4845 0.0405 2.0621−0.0051 2 0 WCM63_Z1_1 16 68853266 74447514 0.0584 0.6315 1.9592 1.13912 1 WCM63_Z1_1 16 74452059 90162163 −0.7075 −0.2088 1.7333 −0.0027 2 0WCM63_Z1_1 17 131595 8090556 −0.0227 0.5444 1.9528 0.964 2 1 WCM63_Z1_117 8092612 81083455 0.3817 0.9754 1.9703 1.962 2 2 WCM63_Z1_1 18 4820923865917 −0.1168 0.4429 1.8372 0.8814 2 1 WCM63_Z1_1 18 2386634678005224 −0.5546 −0.0374 1.2957 0.6531 1 1 WCM63_Z1_1 19 281503 590839230.0139 0.5837 1.9865 1.0109 2 1 WCM63_Z1_1 2 41612 11341155 0.15320.7328 1.7647 1.559 2 2 WCM63_Z1_1 2 11341482 17692196 −0.7778 −0.28841.0439 0.5938 1 1 WCM63_Z1_1 2 17696573 17888572 0.6026 1.2079 NA NA NANA WCM63_Z1_1 2 17889918 26863417 0.818 1.4328 3.8944 1.5051 4 2WCM63_Z1_1 2 26864126 47596234 0.5156 1.1165 2.9203 1.416 3 1 WCM63_Z1_12 47596923 67630744 −0.0999 0.4611 1.8541 0.899 2 1 WCM63_Z1_1 267630982 74275496 −0.5087 0.0136 1.0274 0.9916 1 1 WCM63_Z1_1 2 7430071774757554 0.0221 0.5925 NA NA NA NA WCM63_Z1_1 2 74757804 80874991 0.58841.1929 NA NA NA NA WCM63_Z1_1 2 84517973 96858129 0.2781 0.8657 1.86471.7797 2 2 WCM63_Z1_1 2 96859034 116497429 0.6012 1.2063 2.7864 1.8286 32 WCM63_Z1_1 2 116503691 125671779 −0.5346 −0.0151 1.9857 −0.0065 2 0WCM63_Z1_1 2 127413867 141533723 −1.4031 −1.024 0.9903 −0.0068 1 0WCM63_Z1_1 2 141571257 142237986 0.0405 0.6123 NA NA NA NA WCM63_Z1_1 2142567961 174131113 0.2498 0.8357 2.6397 0.9297 3 1 WCM63_Z1_1 2174131421 242946604 −0.0226 0.5445 1.934 0.9829 2 1 WCM63_Z1_1 20 6839662904932 0.3719 0.9651 1.9521 1.9521 2 2 WCM63_Z1_1 21 9907313 48084282−0.0663 0.4974 1.8624 0.9609 2 1 WCM63_Z1_1 22 16287437 51215152 0.00450.5736 1.9776 0.9988 2 1 WCM63_Z1_1 3 239377 15686250 −0.5122 0.00981.0214 0.9923 1 1 WCM63_Z1_1 3 15686532 21706501 −0.0648 0.499 1.9040.9224 2 1 WCM63_Z1_1 3 21792384 33183909 −0.4154 0.1169 1.1848 0.984 11 WCM63_Z1_1 3 33194345 49298205 0.0172 0.5873 2.0059 0.999 2 1WCM63_Z1_1 3 49298375 56600990 −0.4996 0.0237 1.0493 0.9839 1 1WCM63_Z1_1 3 56603355 62118332 −0.0058 0.5626 1.9358 1.018 2 1WCM63_Z1_1 3 62142766 66428224 0.4881 1.0876 NA NA NA NA WCM63_Z1_1 366430811 97888405 0.7136 1.3239 3.4003 1.6067 3 2 WCM63_Z1_1 3 97888572116163765 0.3188 0.9089 1.9194 1.8358 2 2 WCM63_Z1_1 3 116569172132036371 −0.0748 0.4882 1.9492 0.8562 2 1 WCM63_Z1_1 3 132051162167183428 0.5384 1.1405 3.4968 0.9124 3 1 WCM63_Z1_1 3 167184936197894726 0.8185 1.4333 4.4833 0.918 4 1 WCM63_Z1_1 4 59327 49063852−0.5442 −0.0259 1.0599 0.9046 1 1 WCM63_Z1_1 4 52709800 69056991 0.68211.291 3.8053 1.0886 4 1 WCM63_Z1_1 4 69094507 82355821 0.9277 1.54693.8469 1.9968 4 2 WCM63_Z1_1 4 82362035 83277787 0.6239 1.2302 NA NA NANA WCM63_Z1_1 4 83278007 130023828 0.0405 0.6123 1.7255 1.3319 2 1WCM63_Z1_1 4 130030652 135121668 −2.4686 −2.4987 NA NA NA NA WCM63_Z1_14 135122024 143007392 −0.9161 −0.4465 1.4858 −0.0182 1 0 WCM63_Z1_1 4143029296 189026071 −0.3476 0.1914 1.3812 0.9025 1 1 WCM63_Z1_1 4189026391 190426502 −0.056 0.5085 NA NA NA NA WCM63_Z1_1 5 14053245695884 −0.4434 0.086 1.2385 0.8844 1 1 WCM63_Z1_1 5 49698142 66480250−1.4152 −1.0388 0.9674 0.0061 1 0 WCM63_Z1_1 5 66481790 82406916 −0.5682−0.0525 0.9943 0.9341 1 1 WCM63_Z1_1 5 82491672 110730437 −1.335 −0.94091.0669 −0.0252 1 0 WCM63_Z1_1 5 110784859 112102072 −3.2003 −4.0035 NANA NA NA WCM63_Z1_1 5 112102961 115230851 −1.3602 −0.9716 1.0055 0.01431 0 WCM63_Z1_1 5 115238635 115249078 0.2105 0.7939 NA NA NA NAWCM63_Z1_1 5 115297939 130721295 −1.3196 −0.9222 1.0368 0.0186 1 0WCM63_Z1_1 5 130726741 180687776 −0.5071 0.0155 1.0209 1.0007 1 1WCM63_Z1_1 6 203479 393152 0.4715 1.0702 NA NA NA NA WCM63_Z1_1 6 39484718572091 0.3236 0.9139 1.9261 1.8423 2 2 WCM63_Z1_1 6 19838312 84573910−0.0491 0.5159 1.8891 0.9707 2 1 WCM63_Z1_1 6 84618797 88346163 −0.6576−0.1526 NA NA NA NA WCM63_Z1_1 6 88360928 170893408 −0.099 0.4621 1.82260.9324 2 1 WCM63_Z1_1 7 193245 57529304 0.5785 1.1826 2.6603 1.8793 3 2WCM63_Z1_1 7 57529628 158937400 −0.0796 0.483 1.8458 0.9496 2 1WCM63_Z1_1 8 190907 37593994 0.228 0.8125 3.5117 9.00E−04 4 0 WCM63_Z1_18 37595535 37632892 1.3761 2.0098 NA NA NA NA WCM63_Z1_1 8 3763353343197370 0.8718 1.4888 3.2646 2.3485 3 2 WCM63_Z1_1 8 47752739 523257671.5551 2.1935 NA NA NA NA WCM63_Z1_1 8 52336239 59720311 0.7191 1.32974.9805 0.0464 5 0 WCM63_Z1_1 8 59720741 92212918 1.1924 1.8207 5.23421.831 5 2 WCM63_Z1_1 8 92219027 98289897 0.9191 1.5379 4.8965 0.9109 5 1WCM63_Z1_1 8 98656803 110255528 1.5198 2.1573 4.5521 4.3692 5 4WCM63_Z1_1 8 110283353 116426487 1.1007 1.726 5.1409 1.4754 5 1WCM63_Z1_1 8 116426675 146279527 0.7817 1.395 5.2614 −0.0015 5 0WCM63_Z1_1 9 116846 84528514 −0.2083 0.3436 1.5615 0.9764 2 1 WCM63_Z1_19 84529352 141111414 −0.0611 0.503 1.8894 0.9449 2 1 WCM63_Z1_1 X2707715 22292191 −0.6009 −0.0891 NA NA NA NA WCM63_Z1_1 X 2229225927765165 0.3187 0.9088 NA NA NA NA WCM63_Z1_1 X 27765759 48801499 −0.645−0.1384 NA NA NA NA WCM63_Z1_1 X 48814257 50378620 0.4123 1.0077 NA NANA NA WCM63_Z1_1 X 50556923 154509348 −0.5951 −0.0826 NA NA NA NAWCM63_Z19_1 1 69590 249212401  6.00E−04 0.058 1.4412 0.6409 1 1WCM63_Z19_1 10 226048 135440080 −0.0276 NA −0.4023 −1.3834 0 −1 WCM63_Z19_1 11 193106 134856603 −0.0251 NA −0.0366 −1.4124 0 −1 WCM63_Z19_1 12 148674 133810703 −0.0278 NA −0.2203 −1.5936 0 −2 WCM63_Z19_1 13 19600515 115089411 −0.025 NA 0.5628 −1.9926 1 −2 WCM63_Z19_1 14 19377701 107283210 −5.00E−04 −0.0482 2.0668 −0.1325 2 0WCM63_Z19_1 15 20170150 102517639 0.0019 0.1791 1.8331 0.4312 2 0WCM63_Z19_1 16 66966 90162169 0.0358 1.8113 3.5095 3.5095 4 4WCM63_Z19_1 17 131595 81083455 0.0395 1.916 4.4933 3.0545 4 3WCM63_Z19_1 18 48236 78005210 −0.0155 NA 0.523 −0.6641 1 −1  WCM63_Z19_119 281403 59083968 0.0482 2.1368 5.0182 3.7774 5 4 WCM63_Z19_1 2 41615242946589 −5.00E−04 −0.046 1.1685 0.7686 1 1 WCM63_Z19_1 20 6835162904925 0.0292 1.6078 3.0479 3.0479 3 3 WCM63_Z19_1 21 9907283 48084277−0.011 −2.0575 1.1334 −0.6529 1 −1  WCM63_Z19_1 22 16287434 512151520.0247 1.4459 3.3347 2.114 3 2 WCM63_Z19_1 3 239436 197894719 0.01230.8926 2.3608 1.3522 2 1 WCM63_Z19_1 4 59345 190426502 −0.0301 NA−0.2828 −1.8498 0 −2  WCM63_Z19_1 5 140532 180687800 −0.0246 NA −0.1992−1.1823 0 −1  WCM63_Z19_1 6 203509 170893411 −0.0382 NA −0.836 −2.3941−1  −2  WCM63_Z19_1 7 193451 158937416 −0.0298 NA −0.3609 −1.7322 0 −2 WCM63_Z19_1 8 190907 146279481 −0.02 NA 0.2134 −0.97 0 −1  WCM63_Z19_1 9116938 141111414 −0.0328 NA −0.76 −1.7375 −1  −2  WCM63_Z19_1 X 2707716154509348 −0.0797 NA NA NA NA NA WCM63_Z19_2 1 69649 84640739 −0.18060.6087 2.082 0.9678 2 1 WCM63_Z19_2 1 84641480 104114376 −0.6114 −0.01142.0881 −0.1038 2 0 WCM63_Z19_2 1 104114732 111217270 −0.1438 0.65832.1835 0.9728 2 1 WCM63_Z19_2 1 111434093 117307165 −0.4918 0.16942.1207 0.1284 2 0 WCM63_Z19_2 1 117311331 119427530 −0.2246 0.54881.9212 1.0046 2 1 WCM63_Z19_2 1 119427687 120387120 0.1875 1.0871 NA NANA NA WCM63_Z19_2 1 120436981 186329455 0.411 1.3621 3.1459 1.9955 3 2WCM63_Z19_2 1 186329951 202406993 0.1041 0.9818 2.0428 1.9071 2 2WCM63_Z19_2 1 202407199 205211164 0.4284 1.3833 3.1278 2.0893 3 2WCM63_Z19_2 1 205215773 214209123 0.1215 1.0039 2.0309 1.98 2 2WCM63_Z19_2 1 214454711 249212402 −0.2259 0.547 1.9509 0.9712 2 1WCM63_Z19_2 10 226021 135440080 −0.21 0.5687 2.0351 0.9313 2 1WCM63_Z19_2 11 193112 36614397 −0.2175 0.5586 2.0279 0.9177 2 1WCM63_Z19_2 11 36614835 48286303 −0.5658 0.0585 2.1505 −0.0677 2 0WCM63_Z19_2 11 48327975 59834432 −0.1571 0.6403 2.0284 1.0889 2 1WCM63_Z19_2 11 59837097 65547781 0.1284 1.0127 2.0407 1.9947 2 2WCM63_Z19_2 11 65547974 71155945 0.6307 1.6239 4.1575 2.0068 4 2WCM63_Z19_2 11 71164394 93463117 0.1448 1.0335 2.0832 2.0108 2 2WCM63_Z19_2 11 93463415 107299831 −0.1836 0.6046 1.9283 1.1129 2 1WCM63_Z19_2 11 107300172 126969289 −0.6102 −0.0095 2.0673 −0.0804 2 0WCM63_Z19_2 11 128332352 134856604 0.1521 1.0427 2.1172 2.0029 2 2WCM63_Z19_2 12 148675 43793017 0.1014 0.9785 1.9929 1.9478 2 2WCM63_Z19_2 12 43817588 50867846 −0.2038 0.5772 2.0422 0.9417 2 1WCM63_Z19_2 12 50869561 67197936 0.0282 0.8845 1.8771 1.8151 2 2WCM63_Z19_2 12 67663563 106848421 −0.235 0.5346 1.8896 1.0074 2 1WCM63_Z19_2 12 106851001 108642092 −0.1285 0.6787 NA NA NA NAWCM63_Z19_2 12 108675125 111760276 0.3994 1.3482 3.2337 1.8581 3 2WCM63_Z19_2 12 111772250 116406796 −0.2247 0.5487 1.943 0.9825 2 1WCM63_Z19_2 12 116408538 121471337 0.3657 1.3072 2.6072 2.3421 3 2WCM63_Z19_2 12 121471525 122763598 0.0464 0.908 1.9586 1.7944 2 2WCM63_Z19_2 12 122773055 123968766 −0.1835 0.6047 2.1076 0.9338 2 1WCM63_Z19_2 12 123969764 124821696 0.2169 1.124 2.2882 2.0707 2 2WCM63_Z19_2 12 124824663 132391447 −0.1955 0.5884 2.0815 0.9257 2 1WCM63_Z19_2 12 132392049 133810703 0.1388 1.0259 2.0902 1.9821 2 2WCM63_Z19_2 13 19600515 30854269 −0.2197 0.5555 1.8974 1.042 2 1WCM63_Z19_2 13 30857900 88329759 −0.6282 −0.0374 2.0274 −0.0785 2 0WCM63_Z19_2 13 88330022 115089411 −0.1542 0.6443 2.1304 0.9956 2 1WCM63_Z19_2 14 19377718 34993982 0.0998 0.9763 2.0226 1.9123 2 2WCM63_Z19_2 14 34998655 107283080 −0.2069 0.573 2.0063 0.9689 2 1WCM63_Z19_2 15 20170150 22382897 −0.6885 −0.132 1.4524 0.3728 1 0WCM63_Z19_2 15 22383189 34380331 −0.1777 0.6126 2.079 0.9791 2 1WCM63_Z19_2 15 34382621 102517646 −0.5589 0.0689 1.1109 0.987 1 1WCM63_Z19_2 16 66955 27353498 0.4571 1.4178 4.2544 1.0891 4 1WCM63_Z19_2 16 27356242 50250077 0.679 1.6805 4.4559 1.955 4 2WCM63_Z19_2 16 50251538 53738097 0.16 1.0526 2.1396 2.009 2 2WCM63_Z19_2 16 53844114 69602441 −0.5505 0.0816 2.1614 −0.0451 2 0WCM63_Z19_2 16 69660405 73177675 0.2376 1.1497 2.2352 2.2021 2 2WCM63_Z19_2 16 73517324 90162177 −0.5355 0.1043 2.1543 −0.0044 2 0WCM63_Z19_2 17 131595 25636295 −0.1238 0.685 2.1271 1.0883 2 1WCM63_Z19_2 17 25639382 81083419 0.1933 1.0944 2.1352 2.1352 2 2WCM63_Z19_2 18 48209 225134 −0.0837 0.7383 NA NA NA NA WCM63_Z19_2 18225400 12785819 0.1943 1.0956 2.236 2.0381 2 2 WCM63_Z19_2 18 1278812778005210 −0.1593 0.6374 2.0665 1.0446 2 1 WCM63_Z19_2 19 281491 59083951−0.1253 0.683 2.1522 1.0588 2 1 WCM63_Z19_2 2 41615 11315092 0.14561.0344 3.1503 0.9464 3 1 WCM63_Z19_2 2 11317937 16745309 −1.0517 −0.76221.1085 0.0707 1 0 WCM63_Z19_2 2 16746986 17888615 −0.1346 0.6706 NA NANA NA WCM63_Z19_2 2 17889918 44104808 0.1393 1.0264 2.073 2.0009 2 2WCM63_Z19_2 2 44105051 68365887 −0.2757 0.4785 1.9033 0.8833 2 1WCM63_Z19_2 2 68368831 72707874 −0.5652 0.0594 2.1104 −0.0264 2 0WCM63_Z19_2 2 72719504 74328649 −1.1239 −0.9035 1.0464 0.0227 1 0WCM63_Z19_2 2 74328895 74777384 −0.5224 0.1238 NA NA NA NA WCM63_Z19_2 274779681 84954858 −0.1757 0.6153 NA NA NA NA WCM63_Z19_2 2 84960570116497383 0.1157 0.9966 2.2741 1.7166 2 2 WCM63_Z19_2 2 116503691125669078 −0.5285 0.1147 2.1236 0.0419 2 0 WCM63_Z19_2 2 125671671141625760 −1.1424 −0.9411 1.0717 −0.03 1 0 WCM63_Z19_2 2 141641548242946607 −0.1733 0.6186 2.1015 0.9692 2 1 WCM63_Z19_2 20 68396 29632635−0.5587 0.0693 1.0682 1.0301 1 1 WCM63_Z19_2 20 29845473 62904925 0.22241.1308 2.2035 2.1762 2 2 WCM63_Z19_2 21 9907291 48084277 0.1621 1.05532.1121 2.0441 2 2 WCM63_Z19_2 22 16287488 51215120 −0.1523 0.6469 2.10241.0292 2 1 WCM63_Z19_2 3 239459 15686776 −0.1242 0.6844 2.0855 1.1286 21 WCM63_Z19_2 3 15686992 33617733 0.1478 1.0372 2.6403 1.4642 3 1WCM63_Z19_2 3 33618724 42632410 0.4508 1.4103 3.1725 2.1432 3 2WCM63_Z19_2 3 42633050 49294426 0.1807 1.0786 3.2014 1.0227 3 1WCM63_Z19_2 3 49294675 56653467 −0.527 0.1169 1.1299 1.039 1 1WCM63_Z19_2 3 56653845 73432623 0.1017 0.9787 2.9242 1.0172 3 1WCM63_Z19_2 3 73432984 121217381 0.4254 1.3796 3.1547 2.0492 3 2WCM63_Z19_2 3 121229015 121339424 0.1169 0.9981 NA NA NA NA WCM63_Z19_23 121340285 129152975 0.6982 1.703 3.2899 3.2216 3 3 WCM63_Z19_2 3129155463 197894713 0.8149 1.8381 4.0155 3.1351 4 3 WCM63_Z19_2 4 5943449019314 0.1582 1.0503 2.1257 2.0161 2 2 WCM63_Z19_2 4 49030719 823778901.1132 2.1763 7.8334 1.2067 8 1 WCM63_Z19_2 4 82378764 133368267 −0.22980.5417 1.9841 0.9272 2 1 WCM63_Z19_2 4 134071300 143045743 −1.1842−1.0273 NA NA NA NA WCM63_Z19_2 4 143067127 153245499 0.5018 1.47134.829 0.7165 5 1 WCM63_Z19_2 4 153247278 178911632 −0.134 0.6714 2.09341.0918 2 1 WCM63_Z19_2 4 183090524 189060715 −0.6223 −0.0282 1.03230.929 1 1 WCM63_Z19_2 4 189061024 190426502 −0.4171 0.2785 NA NA NA NAWCM63_Z19_2 5 140532 45695818 0.167 1.0614 2.3495 1.8244 2 2 WCM63_Z19_25 49698128 66492459 −0.651 −0.0728 1.892 0.0096 2 0 WCM63_Z19_2 567494070 82360047 0.0381 0.8973 1.8985 1.8265 2 2 WCM63_Z19_2 5 82360839130762977 −0.615 −0.0168 2.0419 −0.0651 2 0 WCM63_Z19_2 5 130764604180687803 0.1132 0.9934 2.0061 1.9757 2 2 WCM63_Z19_2 6 203535 3933080.5438 1.5213 NA NA NA NA WCM63_Z19_2 6 394889 19838425 0.2066 1.11112.4839 1.8363 2 2 WCM63_Z19_2 6 19838843 84618750 −0.1938 0.5907 2.02740.9847 2 1 WCM63_Z19_2 6 84624165 88346138 −0.7325 −0.2027 NA NA NA NAWCM63_Z19_2 6 88360921 170893411 −0.2115 0.5667 1.972 0.9904 2 1WCM63_Z19_2 7 193245 57510008 0.3264 1.2593 3.8657 0.9218 4 1WCM63_Z19_2 7 57522211 158937400 0.0373 0.8963 2.0437 1.6789 2 2WCM63_Z19_2 8 190908 37456103 −0.643 −0.0604 1.9743 −0.0563 2 0WCM63_Z19_2 8 37553685 59720303 0.5358 1.5118 4.2585 1.4447 4 1WCM63_Z19_2 8 59720709 103301755 0.6887 1.6919 3.8338 2.6277 4 3WCM63_Z19_2 8 103305906 146279416 0.3626 1.3034 3.9443 0.9919 4 1WCM63_Z19_2 9 116867 28888930 −0.2032 0.5779 2.0615 0.924 2 1WCM63_Z19_2 9 32384732 38411484 0.1338 1.0195 2.0682 1.9861 2 2WCM63_Z19_2 9 38413346 141111414 −0.2067 0.5732 2.0045 0.9711 2 1WCM63_Z19_2 X 2707682 22291762 −0.6149 −0.0166 NA NA NA NA WCM63_Z19_2 X22291972 27765205 0.0855 0.9581 NA NA NA NA WCM63_Z19_2 X 27765657100105218 −0.584 0.0308 NA NA NA NA WCM63_Z19_2 X 100106293 1545093480.0616 0.9275 NA NA NA NA WCM63_Z2_1 1 69590 120491704 −0.2811 −0.39731.0145 0.5041 1 1 WCM63_Z2_1 1 120510178 249212557 0.0801 −0.0095 0.99770.9892 1 1 WCM63_Z2_1 10 226016 9281413 −0.7952 −0.9643 1.0278 −0.0027 10 WCM63_Z2_1 10 11047400 13167995 −0.3225 −0.4422 0.9607 0.5112 1 1WCM63_Z2_1 10 13169898 17641339 −0.787 −0.9551 1.0178 0.0138 1 0WCM63_Z2_1 10 17686365 23257397 −0.357 −0.4798 0.9272 0.507 1 1WCM63_Z2_1 10 23270419 28527518 0.0693 −0.0209 1.0412 0.93 1 1WCM63_Z2_1 10 28822523 30336727 −0.2485 −0.362 0.9608 0.5954 1 1WCM63_Z2_1 10 30602783 35896538 −0.6863 −0.8424 1.0935 0.0219 1 0WCM63_Z2_1 10 35896983 56424006 0.045 −0.0469 1 0.936 1 1 WCM63_Z2_1 1057359710 59064251 −0.9505 −1.1402 NA NA NA NA WCM63_Z2_1 10 59956189135440117 0.0743 −0.0156 0.9903 0.9882 1 1 WCM63_Z2_1 11 193144 52554440.1984 0.1161 1.2307 0.9369 1 1 WCM63_Z2_1 11 5263449 40137779 0.0642−0.0264 0.9881 0.9756 1 1 WCM63_Z2_1 11 42210168 49221910 −0.8134−0.9848 0.9424 0.0682 1 0 WCM63_Z2_1 11 49597890 107300165 0.0931 0.00441.0126 0.9934 1 1 WCM63_Z2_1 11 107304361 126968472 −0.8167 −0.98841.0083 −2.00E−04  1 0 WCM63_Z2_1 11 126969289 134856562 0.0929 0.00411.0359 0.9698 1 1 WCM63_Z2_1 12 148674 133810703 0.0831 −0.0062 0.99990.9914 1 1 WCM63_Z2_1 13 19600515 30829619 −0.3055 −0.4237 0.9373 0.55371 1 WCM63_Z2_1 13 30854358 92101017 −0.8846 −1.0652 0.9682 −0.0124 1 0WCM63_Z2_1 13 92345691 115089411 −0.3406 −0.4619 0.9425 0.5096 1 1WCM63_Z2_1 14 19377723 107283213 0.0634 −0.0273 0.9876 0.975 1 1WCM63_Z2_1 15 20170150 102517666 −0.2953 −0.4127 1.0063 0.4961 1 0WCM63_Z2_1 16 66953 1251963 0.416 0.3456 2.0327 0.5087 2 1 WCM63_Z2_1 161252259 33965573 0.6385 0.5784 1.982 1.0043 2 1 WCM63_Z2_1 16 3425680849672214 1.0441 0.999 2.9885 1.0086 3 1 WCM63_Z2_1 16 49672520 536753010.0586 −0.0324 1.0216 0.9341 1 1 WCM63_Z2_1 16 53679551 69496362 −0.8187−0.9907 1.0164 −0.01 1 0 WCM63_Z2_1 16 69602425 69788812 1.008 0.9618 NANA NA NA WCM63_Z2_1 16 69820970 73177676 0.1092 0.0215 1.0323 0.9977 1 1WCM63_Z2_1 16 73517324 90162135 −0.7838 −0.9515 1.0278 0.0065 1 0WCM63_Z2_1 17 131595 21188249 −0.2707 −0.386 1.0123 0.5182 1 1WCM63_Z2_1 17 21191346 25975908 0.0024 −0.0923 1.0763 0.7998 1 1WCM63_Z2_1 17 25981805 47121328 0.1821 0.0989 1.0823 1.0596 1 1WCM63_Z2_1 17 47122370 81083507 0.037 −0.0554 0.9767 0.948 1 1WCM63_Z2_1 18 48236 78005210 0.0489 −0.0427 0.9832 0.9584 1 1 WCM63_Z2_119 281535 59083951 −0.2654 −0.3803 1.0262 0.5103 1 1 WCM63_Z2_1 2 4162390199107 −0.3065 −0.4248 0.9843 0.5055 1 1 WCM63_Z2_1 2 90229327115919809 0.0633 −0.0274 1.0042 0.9582 1 1 WCM63_Z2_1 2 115991546125671840 −0.8239 −0.9965 0.9996 0.0028 1 0 WCM63_Z2_1 2 127413862141641404 −1.6692 −1.9963 0.5029 −0.0016 1 0 WCM63_Z2_1 2 141660586242946607 −0.3253 −0.4453 0.9707 0.4981 1 0 WCM63_Z2_1 20 68396 23967150−0.3028 −0.4209 0.9926 0.5013 1 1 WCM63_Z2_1 20 24523899 30467693 0.32590.2508 1.2412 1.1384 1 1 WCM63_Z2_1 20 30475042 32026712 0.6007 0.53891.9185 0.9872 2 1 WCM63_Z2_1 20 32031205 37121690 0.2395 0.1596 1.18431.0497 1 1 WCM63_Z2_1 20 37126150 62904847 −0.2916 −0.4087 0.9911 0.51551 1 WCM63_Z2_1 21 9907291 48084282 0.1114 0.0238 1.0383 0.995 1 1WCM63_Z2_1 22 16287451 51215134 −0.2511 −0.3648 1.0228 0.5303 1 1WCM63_Z2_1 3 239390 24164472 0.3821 0.3099 1.4847 0.9946 1 1 WCM63_Z2_13 24168987 49095364 0.0869 −0.0022 1.0038 0.9931 1 1 WCM63_Z2_1 349114160 49695542 −0.2181 −0.3291 NA NA NA NA WCM63_Z2_1 3 4969809189528638 0.082 −0.0075 1.016 0.9737 1 1 WCM63_Z2_1 3 93595842 1320362980.6037 0.5421 1.9258 0.9864 2 1 WCM63_Z2_1 3 132051167 132441155 1.2781.2398 NA NA NA NA WCM63_Z2_1 3 133098837 197894713 0.5941 0.5321 1.90350.9885 2 1 WCM63_Z2_1 4 59331 49040138 0.0674 −0.0229 0.9926 0.9758 1 1WCM63_Z2_1 4 49046800 82380654 1.274 1.2357 3.6998 1.0101 4 1 WCM63_Z2_14 83276547 133367616 0.0293 −0.0636 0.9712 0.9426 1 1 WCM63_Z2_1 4133368235 135121501 −3.4541 −5.1881 NA NA NA NA WCM63_Z2_1 4 135121842142949975 −0.8319 −1.0056 1.0049 −0.0088 1 0 WCM63_Z2_1 4 142951306190426502 0.027 −0.066 0.9685 0.942 1 1 WCM63_Z2_1 5 140532 160676630.6083 0.5469 1.9259 0.9959 2 1 WCM63_Z2_1 5 16067862 17275364 0.0369−0.0555 NA NA NA NA WCM63_Z2_1 5 17275799 45695896 0.5996 0.5378 1.94580.9577 2 1 WCM63_Z2_1 5 49698142 66492459 −0.8603 −1.0376 0.9758 −0.00161 0 WCM63_Z2_1 5 67494070 82373138 0.05 −0.0416 0.9933 0.9499 1 1WCM63_Z2_1 5 82406983 110462504 −0.8434 −1.0186 0.9802 0.007 1 0WCM63_Z2_1 5 110560257 112043485 −3.335 −4.8248 NA NA NA NA WCM63_Z2_1 5112090601 130764860 −0.8345 −1.0085 0.9878 0.0063 1 0 WCM63_Z2_1 5130766415 180687808 0.0721 −0.018 0.9928 0.9823 1 1 WCM63_Z2_1 6 20351612296255 −0.2763 −0.392 0.9784 0.5457 1 1 WCM63_Z2_1 6 12934068 185720910.1849 0.1018 1.114 1.0322 1 1 WCM63_Z2_1 6 19838288 56323827 −0.2829−0.3992 1.0032 0.5133 1 1 WCM63_Z2_1 6 56324990 66205172 0.0352 −0.05730.9857 0.9365 1 1 WCM63_Z2_1 6 68598997 84573919 −0.3888 −0.5144 0.94990.4503 1 0 WCM63_Z2_1 6 84618756 88331194 −0.8149 −0.9864 NA NA NA NAWCM63_Z2_1 6 88346168 119238820 −0.3156 −0.4347 0.9456 0.5341 1 1WCM63_Z2_1 6 119243243 119399331 −1.5824 −1.8881 NA NA NA NA WCM63_Z2_16 119501086 170893437 −0.3255 −0.4455 0.9435 0.5252 1 1 WCM63_Z2_1 7193222 64254947 0.6135 0.5523 1.9836 0.9492 2 1 WCM63_Z2_1 7 64275300158937416 0.0605 −0.0303 1.0689 0.8895 1 1 WCM63_Z2_1 8 190906 37456103−0.8111 −0.9821 1.0124 0 1 0 WCM63_Z2_1 8 37553685 80523432 0.6602 0.6011.9973 1.0363 2 1 WCM63_Z2_1 8 80549097 126194478 0.4327 0.3631 1.49141.081 1 1 WCM63_Z2_1 8 126369507 146279511 0.1865 0.1035 1.5604 0.5883 21 WCM63_Z2_1 9 116887 141111414 0.0788 −0.0109 0.9999 0.9851 1 1WCM63_Z2_1 X 2707716 46309907 −0.8601 −1.0375 NA NA NA NA WCM63_Z2_1 X46322675 154509348 0.5647 0.5013 NA NA NA NA WCM677 1 14907 59243590.1387 0.1862 1.1519 1.1236 1 1 WCM677 1 5924444 16455987 −0.3927−0.9602 1.0169 0.0111 1 0 WCM677 1 16456656 18024350 −0.3157 −0.75930.9173 0.2642 1 0 WCM677 1 18149510 18962716 −0.3886 −0.949 NA NA NA NAWCM677 1 18965426 145457631 0.0368 −4.00E−04 0.9997 0.9997 1 1 WCM677 1145457926 156623141 0.3975 0.6188 1.9329 1.1383 2 1 WCM677 1 156626132160264666 0.0778 0.076 1.1085 0.9998 1 1 WCM677 1 160265672 2492134640.3888 0.6051 1.9184 1.1238 2 1 WCM677 10 226104 135438994 0.0333−0.0069 0.9952 0.9952 1 1 WCM677 11 193096 103814416 0.0434 0.01211.0198 0.9971 1 1 WCM677 11 103818411 126870418 −0.4221 −1.0416 0.95250.0191 1 0 WCM677 11 126873592 134605906 0.0162 −0.0396 0.999 0.9469 1 1WCM677 12 148388 9748018 0.0113 −0.0489 1.0056 0.9277 1 1 WCM677 129750669 15834157 −0.433 −1.0727 0.9604 −0.0095 1 0 WCM677 12 15835855133810869 0.0392 0.0042 1.0029 1.0029 1 1 WCM677 13 19042004 410328530.005 −0.0611 0.9586 0.9586 1 1 WCM677 13 41034618 70535607 −0.4914−1.2469 0.9145 −0.0718 1 0 WCM677 13 70549818 115089411 0.0045 −0.0620.9579 0.9579 1 1 WCM677 14 19110194 107283270 0.0432 0.0118 1.00821.0082 1 1 WCM677 15 20083896 102514214 −0.1726 −0.4249 0.9211 0.5687 11 WCM677 16 64396 25712440 0.0555 0.0346 1.0511 0.9976 1 1 WCM677 1625719928 32402223 −0.5158 −1.324 0.8419 −0.043 1 0 WCM677 16 3241642948675332 −0.0371 −0.1431 1.2623 0.5489 1 1 WCM677 16 48686063 61935280−0.4145 −1.0204 0.9883 −0.0023 1 0 WCM677 16 62055230 70177614 0.06040.0439 1.075 0.9868 1 1 WCM677 16 70180141 90260461 −0.4092 −1.00550.969 0.0272 1 0 WCM677 17 131595 81187813 0.0394 0.0046 1.0032 1.0032 11 WCM677 18 47661 78005110 0.0086 −0.054 1.9179 0.0086 2 0 WCM677 19105050 59093645 0.0208 −0.0308 0.9789 0.9789 1 1 WCM677 2 41612116601843 0.0151 −0.0416 0.9716 0.9716 1 1 WCM677 2 118572355 148657339−0.4584 −1.1466 0.8894 0.014 1 0 WCM677 2 148657490 162567121 0.004−0.0628 0.9666 0.9482 1 1 WCM677 2 162627444 189447071 −0.2264 −0.54550.7606 0.6097 1 1 WCM677 2 189447335 218577646 −0.0021 −0.0747 0.94950.9495 1 1 WCM677 2 218604181 242814884 −0.4191 −1.0334 0.9562 0.0209 10 WCM677 2 242815059 243037013 −0.4061 −0.997 NA NA NA NA WCM677 2068299 62934617 −0.1562 −0.3894 1.0308 0.4961 1 0 WCM677 21 959031148084175 0.0371  1.00E−04 1.0001 1.0001 1 1 WCM677 22 16159014 51219089−0.3764 −0.9161 1.0485 0.0114 1 0 WCM677 3 239436 97634601 −0.0818−0.233 0.87 0.8317 1 1 WCM677 3 97643140 118913289 −0.4474 −1.11430.9029 0.0209 1 0 WCM677 3 118917943 197896801 0.2851 0.4372 1.596 1.1122 1 WCM677 4 53344 117220900 0.012 −0.0476 0.9676 0.9676 1 1 WCM677 4118004865 138149449 −0.5255 −1.3555 0.8495 −0.0678 1 0 WCM677 4138440988 190904482 −0.0182 −0.1061 0.9291 0.9291 1 1 WCM677 5 905761443182 −0.0028 −0.0759 1.2369 0.6605 1 1 WCM677 5 1461779 26906284−0.2205 −0.5321 0.8683 0.5148 1 1 WCM677 5 26906844 180687830 0.0272−0.0185 0.9873 0.9873 1 1 WCM677 6 203588 80411756 −0.1962 −0.47720.9784 0.4583 1 0 WCM677 6 80412040 93967201 −0.4928 −1.2513 0.9075−0.0674 1 0 WCM677 6 93967851 170892873 −0.2247 −0.5417 0.9419 0.432 1 0WCM677 7 193245 5545157 0.1547 0.2146 1.2096 1.1113 1 1 WCM677 7 5553263127231302  5.00E−04 −0.0696 0.9713 0.9345 1 1 WCM677 7 127231699158937074 0.0696 0.061 1.0663 1.02 1 1 WCM677 8 163438 43415878 −0.1982−0.4817 1.4454 −0.0132 1 0 WCM677 8 47886108 51705393 0.9305 1.3886 NANA NA NA WCM677 8 52232487 65496220 0.6003 0.927 3.7721 0.0305 4 0WCM677 8 65509349 146279472 0.9945 1.4736 3.9497 1.6047 4 2 WCM677 914903 103348297 0.0128 −0.0459 0.9687 0.9687 1 1 WCM677 9 103348634112711585 −0.4354 −1.0796 0.9723 −0.0259 1 0 WCM677 9 112713081141107526 0.1174 0.1482 1.1082 1.1082 1 1 WCM677 X 2700087 154493609−0.0944 −0.2588 NA NA NA NA WCM677_Z12_1 1 721476 3809495 0.0788 0.03511.0402 1.0091 1 1 WCM677_Z12_1 1 3816745 18962771 −0.8752 −0.9322 1.04756.00E−04 1 0 WCM677_Z12_1 1 19018405 55538462 0.0897 0.0461 1.03251.0325 1 1 WCM677_Z12_1 1 55539559 109649631 −0.033 −0.0778 0.96 0.93511 1 WCM677_Z12_1 1 109650634 145109583 0.0585 0.0146 1.0459 0.9745 1 1WCM677_Z12_1 1 145112393 156568810 0.6574 0.6185 2.0498 1.0206 2 1WCM677_Z12_1 1 156571224 160254843 0.061 0.0172 1.0294 0.9946 1 1WCM677_Z12_1 1 160259952 249212424 0.6143 0.575 1.9771 1.0023 2 1WCM677_Z12_1 10 225981 135440105 0.0408 −0.0033 0.9977 0.9977 1 1WCM677_Z12_1 11 193105 103720698 0.0678 0.024 1.0168 1.0168 1 1WCM677_Z12_1 11 103780503 126969252 −0.8998 −0.9573 1.0296 4.00E−04 1 0WCM677_Z12_1 11 128332328 134856563 0.0708 0.0271 1.0324 1.0056 1 1WCM677_Z12_1 12 148639 7061279 0.0958 0.0523 1.0683 1.0055 1 1WCM677_Z12_1 12 7064121 7633746 −0.1005 −0.146 NA NA NA NA WCM677_Z12_112 7635291 8090973 −0.9807 −1.0399 NA NA NA NA WCM677_Z12_1 12 81924528925987 0.0478 0.0038 NA NA NA NA WCM677_Z12_1 12 8930225 9087059−0.9416 −1 NA NA NA NA WCM677_Z12_1 12 9087727 9465276 0.0099 −0.0345 NANA NA NA WCM677_Z12_1 12 9571404 15835885 −0.9617 −1.0204 0.991 −0.00511 0 WCM677_Z12_1 12 16035709 59313789 0.0661 0.0223 1.0248 1.0063 1 1WCM677_Z12_1 12 59917206 103670968 −0.0301 −0.0749 0.9619 0.9369 1 1WCM677_Z12_1 12 103695973 133810896 0.0699 0.0262 1.0224 1.0142 1 1WCM677_Z12_1 13 19600515 40362474 0.0066 −0.0378 0.987 0.9614 1 1WCM677_Z12_1 13 41133777 70549835 −0.9596 −1.0184 0.9874 0 1 0WCM677_Z12_1 13 70681400 115089411 0.0107 −0.0336 1.0066 0.9474 1 1WCM677_Z12_1 14 19377712 107283068 0.0429 −0.0011 0.9992 0.9992 1 1WCM677_Z12_1 15 20170094 24922202 −0.3099 −0.3579 0.8554 0.7052 1 1WCM677_Z12_1 15 24922401 102517659 −0.3641 −0.4128 1.0001 0.5022 1 1WCM677_Z12_1 16 67604 26147480 0.0803 0.0367 1.032 1.0196 1 1WCM677_Z12_1 16 27078221 32013471 −0.899 −0.9565 1.0281 0.0025 1 0WCM677_Z12_1 16 32077496 48643772 −0.0066 −0.0511 0.9993 0.931 1 1WCM677_Z12_1 16 49193569 61935359 −0.9052 −0.9628 1.0257 4.00E−04 1 0WCM677_Z12_1 16 62055118 70191029 0.082 0.0383 1.0601 0.9937 1 1WCM677_Z12_1 16 70211274 90233642 −0.9144 −0.9722 1.0192 3.00E−04 1 0WCM677_Z12_1 17 131595 81083567 0.071 0.0272 1.0191 1.0191 1 1WCM677_Z12_1 18 48236 78005164 0.0178 −0.0265 1.9638 −2.00E−04  2 0WCM677_Z12_1 19 281506 59083985 0.0703 0.0265 1.0186 1.0186 1 1WCM677_Z12_1 2 41623 11802360 0.0136 −0.0307 0.9958 0.9622 1 1WCM677_Z12_1 2 11809731 11853913 −0.9499 −1.0084 NA NA NA NAWCM677_Z12_1 2 11905676 116599858 0.0241 −0.0201 0.9912 0.9812 1 1WCM677_Z12_1 2 118572384 144765060 −0.9324 −0.9906 1.0064 2.00E−04 1 0WCM677_Z12_1 2 144899623 145274873 −0.8509 −0.9075 NA NA NA NAWCM677_Z12_1 2 147345768 162274748 0.0221 −0.0221 1.0137 0.956 1 1WCM677_Z12_1 2 162275474 188332522 −0.4062 −0.4555 0.9629 0.4956 1 0WCM677_Z12_1 2 188343519 207814400 −0.0099 −0.0545 0.9736 0.9522 1 1WCM677_Z12_1 2 207820276 208485372 −1.0382 −1.0986 NA NA NA NAWCM677_Z12_1 2 208486581 218604265 0.0267 −0.0175 1.0109 0.965 1 1WCM677_Z12_1 2 218620846 242946597 −0.9099 −0.9677 1.0223 3.00E−04 1 0WCM677_Z12_1 20 68406 33080396 −0.3338 −0.3821 1.0254 0.5092 1 1WCM677_Z12_1 20 33092196 33442624 −1.5882 −1.6632 NA NA NA NAWCM677_Z12_1 20 33444677 49508567 −0.2335 −0.2806 1.0875 0.5591 1 1WCM677_Z12_1 20 49509045 62904932 −0.3449 −0.3934 1.0113 0.5114 1 1WCM677_Z12_1 21 9907284 48084253 0.0421 −0.0019 1.0118 0.9856 1 1WCM677_Z12_1 22 16287438 51215152 −0.8702 −0.9271 1.0565 −0.0047 1 0WCM677_Z12_1 3 239347 89462368 −0.3454 −0.3939 1.021 0.5012 1 1WCM677_Z12_1 3 89468375 97655642 0.1867 0.1441 NA NA NA NA WCM677_Z12_13 97660104 118878762 −0.9723 −1.0313 0.9781 4.00E−04 1 0 WCM677_Z12_1 3118905598 197894726 0.3397 0.2984 1.4703 0.9892 1 1 WCM677_Z12_1 4 59448117220900 0.0079 −0.0365 0.9819 0.9681 1 1 WCM677_Z12_1 4 118005455135122163 −0.9915 −1.0509 0.9631 0.0022 1 0 WCM677_Z12_1 4 138442430190426502 −0.0135 −0.0581 0.9702 0.9508 1 1 WCM677_Z12_1 5 14068424535261 −0.3359 −0.3843 0.985 0.5472 1 1 WCM677_Z12_1 5 24535917180687773 0.029 −0.0152 0.9895 0.9895 1 1 WCM677_Z12_1 6 203466 80383517−0.3638 −0.4126 1.0078 0.4947 1 0 WCM677_Z12_1 6 80406233 93953228−0.9481 −1.0066 0.9929 0.0026 1 0 WCM677_Z12_1 6 93955019 170893415−0.4042 −0.4535 0.9923 0.4682 1 0 WCM677_Z12_1 7 193254 158937416 0.035−0.0091 0.9997 0.9877 1 1 WCM677_Z12_1 8 190906 43212026 −0.36 −0.40871.5091 −0.0025 2 0 WCM677_Z12_1 8 47752739 51465616 1.3758 1.3406 NA NANA NA WCM677_Z12_1 8 51571163 65493792 0.9672 0.9301 3.8017 0.0091 4 0WCM677_Z12_1 8 65494220 146279508 1.4489 1.414 3.855 1.4744 4 1WCM677_Z12_1 9 17055 8733822 −0.0054 −0.0499 0.9962 0.9357 1 1WCM677_Z12_1 9 12694196 14102457 −1.0131 −1.073 NA NA NA NA WCM677_Z12_19 14113017 103348634 0.032 −0.0121 1.0027 0.9806 1 1 WCM677_Z12_1 9104032203 112969805 −0.9519 −1.0105 0.9927 0 1 0 WCM677_Z12_1 9113006466 141111414 0.0897 0.0462 1.0325 1.0325 1 1 WCM677_Z12_1 X2707734 154509348 −0.0086 −0.0532 NA NA NA NA WCM677_Z16_1 1 7214763809556 0.0839 0.0411 1.0405 1.0172 1 1 WCM677_Z16_1 1 3816750 19018405−0.8529 −0.9359 1.0426 0.0028 1 0 WCM677_Z16_1 1 19027206 555516980.0831 0.0403 1.0283 1.0283 1 1 WCM677_Z16_1 1 55555377 115537573−0.0084 −0.0541 0.9732 0.9533 1 1 WCM677_Z16_1 1 115576128 1452093600.0716 0.0284 1.229 0.8108 1 1 WCM677_Z16_1 1 145281644 156568810 0.65460.6259 2.072 1.0143 2 1 WCM677_Z16_1 1 156571231 160254880 0.0648 0.02141.0651 0.9647 1 1 WCM677_Z16_1 1 160259961 249212369 0.6016 0.57182.0007 0.972 2 1 WCM677_Z16_1 10 225982 135440090 0.0468 0.0029 1.0021.002 1 1 WCM677_Z16_1 11 193152 103327019 0.0702 0.027 1.0252 1.0126 11 WCM677_Z16_1 11 103339332 126969249 −0.8867 −0.9717 1.0178 0.0021 1 0WCM677_Z16_1 11 128332268 134856563 0.0611 0.0176 1.0321 0.9925 1 1WCM677_Z16_1 12 148674 7632561 0.0786 0.0356 1.0345 1.0155 1 1WCM677_Z16_1 12 7633843 8192567 −0.9475 −1.0363 NA NA NA NA WCM677_Z16_112 8192707 9462943 −0.0417 −0.0884 1.1183 0.7628 1 1 WCM677_Z16_1 129465477 15835866 −0.9165 −1.0033 1.0117 −0.014 1 0 WCM677_Z16_1 1216035708 133810703 0.054 0.0103 1.0113 1.003 1 1 WCM677_Z16_1 1319600515 40362489 −0.0071 −0.0527 0.9751 0.9532 1 1 WCM677_Z16_1 1341133852 70535554 −0.9324 −1.0202 0.9982 −0.0121 1 0 WCM677_Z16_1 1370549886 115089411 0.0046 −0.0407 0.9863 0.9582 1 1 WCM677_Z16_1 1419377718 107283047 0.0409 −0.0031 0.9978 0.9978 1 1 WCM677_Z16_1 1520170161 102517646 −0.3452 −0.403 1.0105 0.502 1 1 WCM677_Z16_1 16 6760426147482 0.0653 0.022 1.0216 1.0091 1 1 WCM677_Z16_1 16 2707828232077460 −0.8848 −0.9696 1.0181 0.0032 1 0 WCM677_Z16_1 16 3248646548643776 −0.0115 −0.0573 0.9988 0.9234 1 1 WCM677_Z16_1 16 4919360661935339 −0.8763 −0.9606 1.0232 0.0045 1 0 WCM677_Z16_1 16 6205529870191029 0.0609 0.0175 1.0445 0.9798 1 1 WCM677_Z16_1 16 7021126790233642 −0.8956 −0.9812 1.0064 0.0067 1 0 WCM677_Z16_1 17 13159581083561 0.0684 0.0252 1.0176 1.0176 1 1 WCM677_Z16_1 18 48245 780052140.0159 −0.029 1.9608 −6.00E−04  2 0 WCM677_Z16_1 19 281468 59083988 0.070.0268 1.0188 1.0188 1 1 WCM677_Z16_1 2 41613 116599874 0.0384 −0.00580.996 0.996 1 1 WCM677_Z16_1 2 118572386 144765043 −0.9213 −1.00841.0082 −0.014 1 0 WCM677_Z16_1 2 144899623 147345771 −0.8197 −0.9007 NANA NA NA WCM677_Z16_1 2 147345885 162274748 0.0458 0.0019 1.0178 0.98481 1 WCM677_Z16_1 2 162275518 188343531 −0.4046 −0.465 0.9602 0.4888 1 0WCM677_Z16_1 2 188349537 218604289 −0.0063 −0.0519 0.9756 0.9537 1 1WCM677_Z16_1 2 218620799 242946616 −0.8829 −0.9677 1.0259 −0.0033 1 0WCM677_Z16_1 20 68363 33068922 −0.3396 −0.3973 1.009 0.5096 1 1WCM677_Z16_1 20 33077167 33433156 −1.5817 −1.7219 NA NA NA NAWCM677_Z16_1 20 33437829 62904866 −0.2791 −0.3344 1.0618 0.5245 1 1WCM677_Z16_1 21 9907297 48084277 0.039 −0.0051 1.0067 0.9862 1 1WCM677_Z16_1 22 16287440 51215123 −0.8491 −0.9319 1.0515 −0.0032 1 0WCM677_Z16_1 3 239347 89521623 −0.3387 −0.3964 1.0152 0.5044 1 1WCM677_Z16_1 3 89528647 97634486 0.3279 0.2918 NA NA NA NA WCM677_Z16_13 97655712 118878762 −0.9479 −1.0367 0.9872 −0.0123 1 0 WCM677_Z16_1 3118905654 197894720 0.3353 0.2995 1.4653 0.996 1 1 WCM677_Z16_1 4 59326117220891 −0.0018 −0.0472 0.9728 0.9628 1 1 WCM677_Z16_1 4 118005534135122230 −0.98 −1.0708 0.9572 −0.0051 1 0 WCM677_Z16_1 4 138442299190426502 −0.0157 −0.0615 0.9671 0.9493 1 1 WCM677_Z16_1 5 14057424537589 −0.3561 −0.4144 0.9824 0.5183 1 1 WCM677_Z16_1 5 24593417180687808 0.0379 −0.0063 0.9957 0.9957 1 1 WCM677_Z16_1 6 20347980382863 −0.3564 −0.4148 0.9985 0.5018 1 1 WCM677_Z16_1 6 8038350592231446 −0.9321 −1.0199 0.9942 −0.0079 1 0 WCM677_Z16_1 6 93953208170893450 −0.3874 −0.447 0.9797 0.4874 1 0 WCM677_Z16_1 7 193205158937375 0.0405 −0.0036 1.0016 0.9934 1 1 WCM677_Z16_1 8 19090643211989 −0.3484 −0.4064 1.5085 5.00E−04 2 0 WCM677_Z16_1 8 4775273051465616 1.3941 1.377 NA NA NA NA WCM677_Z16_1 8 51571204 652917930.9578 0.9345 3.8146 0.0079 4 0 WCM677_Z16_1 8 65489068 146279511 1.43281.4162 3.8971 1.4404 4 1 WCM677_Z16_1 9 17086 8733822 −0.0048 −0.05030.9757 0.9558 1 1 WCM677_Z16_1 9 12694040 14088211 −0.8624 −0.9459 NA NANA NA WCM677_Z16_1 9 14102437 103348634 0.0374 −0.0068 1.0035 0.9871 1 1WCM677_Z16_1 9 104032275 112969691 −0.8876 −0.9727 0.9949 0.0242 1 0WCM677_Z16_1 9 113006477 141111414 0.0857 0.043 1.0345 1.026 1 1WCM677_Z16_1 X 2707711 154509348 −0.0164 −0.0623 NA NA NA NA WCM677_Z3_11 721415 3809482 0.0784 0.0509 1.0519 1.0199 1 1 WCM677_Z3_1 1 381674518962795 −0.8736 −0.9419 1.0439 −0.0028 1 0 WCM677_Z3_1 1 1901840565852599 0.0511 0.0227 1.018 1.0138 1 1 WCM677_Z3_1 1 65854024 109294896−0.0478 −0.0793 0.9632 0.9299 1 1 WCM677_Z3_1 1 109295707 1452093670.0198 −0.0095 1.0938 0.893 1 1 WCM677_Z3_1 1 145281677 156568810 0.61290.5987 1.9841 1.0446 2 1 WCM677_Z3_1 1 156571231 160254854 0.0136−0.0158 1.0227 0.9554 1 1 WCM677_Z3_1 1 160259952 249212366 0.577 0.5621.9557 0.997 2 1 WCM677_Z3_1 10 225980 135440080 0.0295  5.00E−04 1.00860.9921 1 1 WCM677_Z3_1 11 193114 103720705 0.0273 −0.0018 1.006 0.9916 11 WCM677_Z3_1 11 103780446 126969303 −0.8987 −0.9685 1.0253 −0.0033 1 0WCM677_Z3_1 11 128332323 134856556 0.0592 0.0311 1.0945 0.9492 1 1WCM677_Z3_1 12 148637 7083589 0.0636 0.0357 1.0694 0.9807 1 1WCM677_Z3_1 12 7169203 7633645 −0.076 −0.1084 NA NA NA NA WCM677_Z3_1 127635307 8090972 −0.9211 −0.9923 NA NA NA NA WCM677_Z3_1 12 81925298926151 0.0886 0.0614 NA NA NA NA WCM677_Z3_1 12 8930196 9087060 −0.9105−0.981 NA NA NA NA WCM677_Z3_1 12 9087720 9355174 0.1525 0.1272 NA NA NANA WCM677_Z3_1 12 9356505 15835878 −0.9227 −0.994 1.0127 −0.0085 1 0WCM677_Z3_1 12 16035736 22208202 0.0277 −0.0013 1.031 0.9671 1 1WCM677_Z3_1 12 22211613 80714467 0.1311 0.1051 1.0922 1.059 1 1WCM677_Z3_1 12 80717554 133810880 −0.007 −0.0371 0.9837 0.9656 1 1WCM677_Z3_1 13 19600515 40362473 −3.00E−04 −0.0302 1.0055 0.953 1 1WCM677_Z3_1 13 41133678 70549848 −0.9451 −1.0177 1.0009 −0.0131 1 0WCM677_Z3_1 13 70681397 115089411 0.0016 −0.0283 1.0069 0.9543 1 1WCM677_Z3_1 14 19377710 107283026 0.0351 0.0063 1.0168 0.9919 1 1WCM677_Z3_1 15 20170126 102517641 −0.3649 −0.408 1.0016 0.5057 1 1WCM677_Z3_1 16 67604 25268368 0.0671 0.0392 1.0403 1.0149 1 1WCM677_Z3_1 16 25704145 32077496 −0.8958 −0.9654 1.034 −0.0097 1 0WCM677_Z3_1 16 32486609 48643776 −0.0057 −0.0357 1.0057 0.9453 1 1WCM677_Z3_1 16 49193515 61935339 −0.9206 −0.9917 1.0014 0.0043 1 0WCM677_Z3_1 16 62055296 70211314 0.0622 0.0342 1.0599 0.9881 1 1WCM677_Z3_1 16 70255159 90233627 −0.879 −0.9476 1.0404 −0.0035 1 0WCM677_Z3_1 17 131595 81083561 0.0488 0.0204 1.0215 1.0069 1 1WCM677_Z3_1 18 48238 78005189 −0.0098 −0.04 1.9561 −0.0109 2 0WCM677_Z3_1 19 281483 59083968 0.0509 0.0225 1.0231 1.0084 1 1WCM677_Z3_1 2 41615 116599829 0.0346 0.0058 1.0164 0.9916 1 1WCM677_Z3_1 2 118572427 144728285 −0.9389 −1.0112 1.0069 −0.0146 1 0WCM677_Z3_1 2 144764822 162567212 −0.0187 −0.0492 0.9755 0.9575 1 1WCM677_Z3_1 2 162627523 189348168 −0.653 −0.7092 1.001 0.2222 1 0WCM677_Z3_1 2 189387510 207655376  9.00E−04 −0.029 0.9942 0.9659 1 1WCM677_Z3_1 2 207656454 208485406 −0.9835 −1.0586 NA NA NA NAWCM677_Z3_1 2 208486582 218620790 −2.00E−04 −0.0302 1.0258 0.9328 1 1WCM677_Z3_1 2 218669266 242946607 −0.8713 −0.9395 1.0456 −0.0028 1 0WCM677_Z3_1 20 68375 33080396 −0.3343 −0.3762 1.0462 0.4948 1 0WCM677_Z3_1 20 33092171 33370089 −1.6804 −1.8144 NA NA NA NA WCM677_Z3_120 33433156 62904925 −0.2786 −0.3183 1.0811 0.523 1 1 WCM677_Z3_1 219907283 48084204 0.039 0.0103 1.0217 0.9926 1 1 WCM677_Z3_1 22 1628743451215120 −0.7392 −0.7999 1.1495 −7.00E−04  1 0 WCM677_Z3_1 3 23934789521717 −0.0931 −0.126 0.9988 0.8339 1 1 WCM677_Z3_1 3 8952864797634521 0.5268 0.5107 NA NA NA NA WCM677_Z3_1 3 97655660 118878762−0.9462 −1.019 0.9895 −0.0026 1 0 WCM677_Z3_1 3 118905658 1978947130.4834 0.4664 1.7857 0.9777 2 1 WCM677_Z3_1 4 59339 25678199 −0.0034−0.0335 0.9841 0.97 1 1 WCM677_Z3_1 4 25678266 114081521 −0.0697 −0.10180.9405 0.9232 1 1 WCM677_Z3_1 4 114095568 117220900 −0.1023 −0.1356 NANA NA NA WCM677_Z3_1 4 118005531 135122158 −1.0546 −1.1344 0.9323−0.0212 1 0 WCM677_Z3_1 4 138442211 190426502 −0.0545 −0.0861 0.95080.9333 1 1 WCM677_Z3_1 5 140657 24593503 −0.3577 −0.4005 0.9965 0.5187 11 WCM677_Z3_1 5 26881462 118580165 −0.012 −0.0423 0.9771 0.9651 1 1WCM677_Z3_1 5 118582886 180660174 0.1081 0.0814 1.069 1.0472 1 1WCM677_Z3_1 5 180660694 180687773 0.0045 −0.0252 NA NA NA NA WCM677_Z3_16 203509 80515697 −0.6156 −0.6699 0.9985 0.2586 1 0 WCM677_Z3_1 680580038 96999725 −0.9418 −1.0142 0.9901 1.00E−04 1 0 WCM677_Z3_1 697000464 170893458 −0.6989 −0.7574 0.9439 0.2392 1 0 WCM677_Z3_1 7193265 158937375 0.0151 −0.0144 0.9962 0.984 1 1 WCM677_Z3_1 8 19090043212026 −0.3422 −0.3844 1.5392 −0.007 2 0 WCM677_Z3_1 8 4775273951465632 1.3866 1.3845 NA NA NA NA WCM677_Z3_1 8 51571179 665177700.9506 0.9425 3.8355 0.0081 4 0 WCM677_Z3_1 8 66525522 146279513 1.42571.4241 3.9051 1.462 4 1 WCM677_Z3_1 9 17091 8733811 −0.0559 −0.08760.9965 0.8857 1 1 WCM677_Z3_1 9 12694039 14088265 −0.9131 −0.9838 NA NANA NA WCM677_Z3_1 9 14102421 103348634 −0.0149 −0.0453 0.9871 0.9511 1 1WCM677_Z3_1 9 104032333 112969726 −0.7696 −0.8319 1.1426 −0.0191 1 0WCM677_Z3_1 9 113006461 141111414 0.1631 0.138 1.1128 1.088 1 1WCM677_Z3_1 X 2707734 154509348 −0.0288 −0.0596 NA NA NA NA WCM677_Z6_11 721476 3809552 0.0476 0.0551 1.0536 1.0243 1 1 WCM677_Z6_1 1 381674119027200 −0.9219 −0.9278 1.0507 6.00E−04 1 0 WCM677_Z6_1 1 1902964259250977 0.0373 0.0448 1.0378 1.0253 1 1 WCM677_Z6_1 1 59359386109655251 −0.0714 −0.065 0.9694 0.9424 1 1 WCM677_Z6_1 1 109656269145209435 0.0105 0.0177 1.0338 0.9909 1 1 WCM677_Z6_1 1 145281646156571231 0.6024 0.6144 2.0287 1.0332 2 1 WCM677_Z6_1 1 156593281160254868 0.0184 0.0257 1.018 1.018 1 1 WCM677_Z6_1 1 160259944249212354 0.5727 0.5845 1.9795 1.0194 2 1 WCM677_Z6_1 10 225995135440068 −0.007 0 1 1 1 1 WCM677_Z6_1 11 193097 103720705 −0.0269−0.0202 0.9931 0.9792 1 1 WCM677_Z6_1 11 103780506 126969289 −0.9559−0.9625 1.026 4.00E−04 1 0 WCM677_Z6_1 11 128332337 134856534 0.06660.0743 1.0869 1.0189 1 1 WCM677_Z6_1 12 148639 7083589 0.0776 0.08541.0707 1.0514 1 1 WCM677_Z6_1 12 7169192 7254681 −0.8726 −0.8776 NA NANA NA WCM677_Z6_1 12 7261027 7633814 0.0817 0.0896 NA NA NA NAWCM677_Z6_1 12 7635293 8090972 −1.0235 −1.0315 NA NA NA NA WCM677_Z6_112 8192440 8926171 0.2656 0.2751 NA NA NA NA WCM677_Z6_1 12 89302119087060 −0.9452 −0.9516 NA NA NA NA WCM677_Z6_1 12 9087756 94654770.3167 0.3266 NA NA NA NA WCM677_Z6_1 12 9571646 15835870 −0.9846−0.9918 1.0004 0.0053 1 0 WCM677_Z6_1 12 16035659 44194268 0.254 0.26351.3916 1.0091 1 1 WCM677_Z6_1 12 44196100 62954390 0.3685 0.3788 1.54661.0539 2 1 WCM677_Z6_1 12 62954589 81537013 0.2601 0.2695 1.4376 0.97321 1 WCM677_Z6_1 12 81545846 133810752 −0.006 0.001 1.0048 0.9967 1 1WCM677_Z6_1 13 19600515 40362474 −0.041 −0.0343 0.9982 0.9548 1 1WCM677_Z6_1 13 41133678 70535533 −1.0047 −1.0123 0.9915 0 1 0WCM677_Z6_1 13 70549848 115089411 −0.0074 −4.00E−04 0.9997 0.9997 1 1WCM677_Z6_1 14 19377712 107283220 0.0051 0.0122 1.0146 1.0024 1 1WCM677_Z6_1 15 20169971 22836062 −0.1741 −0.1689 1.055 0.724 1 1WCM677_Z6_1 15 22840319 102517678 −0.4076 −0.4052 0.9992 0.511 1 1WCM677_Z6_1 16 67604 26147212 0.0325 0.0399 1.0312 1.025 1 1 WCM677_Z6_116 26147555 32013471 −0.9459 −0.9523 1.0332 4.00E−04 1 0 WCM677_Z6_1 1632077421 48643763 −0.061 −0.0546 1.0115 0.9142 1 1 WCM677_Z6_1 1649193498 61935339 −0.973 −0.98 1.0137 2.00E−04 1 0 WCM677_Z6_1 1662055278 70211314 0.0314 0.0388 1.0407 1.0137 1 1 WCM677_Z6_1 1670255159 90233627 −0.937 −0.9432 1.0396 5.00E−04 1 0 WCM677_Z6_1 17131595 81083567 0.0229 0.0302 1.0211 1.0211 1 1 WCM677_Z6_1 18 4821278005226 −0.0264 −0.0196 1.9632 0.0098 2 0 WCM677_Z6_1 19 28148359083953 0.0268 0.0341 1.0281 1.0198 1 1 WCM677_Z6_1 2 41620 116594134−0.0132 −0.0062 0.9977 0.9937 1 1 WCM677_Z6_1 2 116598375 144765061−0.9811 −0.9882 1.008 2.00E−04 1 0 WCM677_Z6_1 2 144899623 145274888−0.8782 −0.8833 NA NA NA NA WCM677_Z6_1 2 147345584 162735643 −0.0317−0.0249 1.0007 0.965 1 1 WCM677_Z6_1 2 162738892 188368391 −0.4472−0.4454 0.9764 0.4924 1 0 WCM677_Z6_1 2 189162253 218604247 −0.0325−0.0258 0.9962 0.9684 1 1 WCM677_Z6_1 2 218620823 242946616 −0.9394−0.9457 1.0378 5.00E−04 1 0 WCM677_Z6_1 20 68363 31024207 −0.4049−0.4025 0.9996 0.5135 1 1 WCM677_Z6_1 20 31024365 33080320 −0.2518−0.2475 1.1083 0.5764 1 1 WCM677_Z6_1 20 33092186 33370041 −1.7601−1.7881 NA NA NA NA WCM677_Z6_1 20 33433156 49209602 −0.2759 −0.27191.0823 0.5742 1 1 WCM677_Z6_1 20 49211093 62904890 −0.3783 −0.3756 1.0480.4936 1 0 WCM677_Z6_1 21 9907315 48084281 −0.0021 0.0049 1.0166 0.99021 1 WCM677_Z6_1 22 16287434 51215153 −0.8994 −0.9049 1.0673 8.00E−04 1 0WCM677_Z6_1 3 239347 89521706 −6.00E−04 0.0065 1.0045 1.0045 1 1WCM677_Z6_1 3 89528647 97634562 0.4945 0.5057 NA NA NA NA WCM677_Z6_1 397655629 118865581 −0.996 −1.0035 0.996 0.0016 1 0 WCM677_Z6_1 3118865801 197894719 0.5405 0.5521 1.9386 0.9938 2 1 WCM677_Z6_1 4 59326117220889 −0.0371 −0.0304 0.987 0.9712 1 1 WCM677_Z6_1 4 118005455135122261 −1.0232 −1.0312 0.9767 0.0019 1 0 WCM677_Z6_1 4 138442426190426502 −0.0588 −0.0523 0.9771 0.9517 1 1 WCM677_Z6_1 5 14044324535387 −0.3982 −0.3957 1.0004 0.5198 1 1 WCM677_Z6_1 5 2453591450124177 −0.0705 −0.0641 0.9797 0.9333 1 1 WCM677_Z6_1 5 50125752109178078 −0.2123 −0.2076 0.9492 0.7828 1 1 WCM677_Z6_1 5 109181596109941012 0.0245 0.0319 NA NA NA NA WCM677_Z6_1 5 109941963 110843043−0.3157 −0.3122 NA NA NA NA WCM677_Z6_1 5 111013692 154396803 0.18380.1926 1.5095 0.7762 2 1 WCM677_Z6_1 5 154397060 155771579 −1.3383−1.3535 NA NA NA NA WCM677_Z6_1 5 155820806 166711862 0.1386 0.1471.4782 0.7363 1 1 WCM677_Z6_1 5 166802355 180687800 0.3229 0.3329 1.49191.0272 1 1 WCM677_Z6_1 6 203545 80515673 −0.4116 −0.4093 0.9987 0.5073 11 WCM677_Z6_1 6 80579988 93973575 −1.0211 −1.0291 0.9782 0.0019 1 0WCM677_Z6_1 6 93974399 170893408 −0.4497 −0.4479 0.9739 0.4923 1 0WCM677_Z6_1 7 193451 158937375 −0.0137 −0.0068 1.0044 0.9863 1 1WCM677_Z6_1 8 190907 43211989 −0.4112 −0.4089 1.5089 −0.0025 2 0WCM677_Z6_1 8 47752745 51442765 1.3358 1.3516 NA NA NA NA WCM677_Z6_1 851449236 66517768 0.9343 0.9483 3.8498 0.0093 4 0 WCM677_Z6_1 8 66525552146279472 1.4106 1.4267 3.8998 1.4767 4 1 WCM677_Z6_1 9 17068 8733822−0.0617 −0.0553 0.9702 0.9546 1 1 WCM677_Z6_1 9 12694158 14088237 −1.034−1.0422 NA NA NA NA WCM677_Z6_1 9 14102457 103348634 −0.0182 −0.01131.0082 0.9762 1 1 WCM677_Z6_1 9 104032309 112969854 −0.4994 −0.49831.4102 0.0057 1 0 WCM677_Z6_1 9 113006491 141111414 0.3648 0.3751 1.54011.0538 2 1 WCM677_Z6_1 X 2707708 154509348 −0.0588 −0.0523 NA NA NA NAWCM677_Z7_1 1 721415 3816741 0.0389 0.0605 1.0513 1.0344 1 1 WCM677_Z7_11 4715508 18962797 −0.9259 −0.9177 1.0527 0.0061 1 0 WCM677_Z7_1 119018405 60299887 0.0165 0.0379 1.0349 1.0183 1 1 WCM677_Z7_1 1 60301047109486557 −0.1033 −0.0831 0.9516 0.9364 1 1 WCM677_Z7_1 1 109493049145209396 −0.0159 0.0052 1.0827 0.9245 1 1 WCM677_Z7_1 1 145281653156571231 0.5828 0.6088 2.0039 1.046 2 1 WCM677_Z7_1 1 156593337160260395 0.0068 0.0281 1.0372 1.0022 1 1 WCM677_Z7_1 1 160261169249212342 0.5421 0.5678 1.9732 0.9913 2 1 WCM677_Z7_1 10 225960135440117 −0.0237 −0.0027 0.9981 0.9981 1 1 WCM677_Z7_1 11 193112103720705 −0.0513 −0.0306 0.9889 0.9691 1 1 WCM677_Z7_1 11 103780446126969303 −0.9667 −0.9593 1.023 0.0056 1 0 WCM677_Z7_1 11 128332453134856626 0.0213 0.0427 1.0987 0.9614 1 1 WCM677_Z7_1 12 148673 70835890.0282 0.0497 1.0497 1.0204 1 1 WCM677_Z7_1 12 7169149 7254681 −0.853−0.8434 NA NA NA NA WCM677_Z7_1 12 7261012 7633833 −0.0231 −0.0021 NA NANA NA WCM677_Z7_1 12 7635291 8192527 −1.0501 −1.0443 NA NA NA NAWCM677_Z7_1 12 8192718 8925979 0.3169 0.3409 NA NA NA NA WCM677_Z7_1 128930225 9087059 −0.8465 −0.8368 NA NA NA NA WCM677_Z7_1 12 90877279465477 0.3275 0.3517 NA NA NA NA WCM677_Z7_1 12 9571416 15835878−1.0046 −0.9979 1.0013 1.00E−04 1 0 WCM677_Z7_1 12 16035656 480735470.2358 0.2592 1.4623 0.9313 1 1 WCM677_Z7_1 12 48075570 62946748 0.3450.3693 1.5235 1.06 2 1 WCM677_Z7_1 12 62949801 81102650 0.2452 0.26871.4489 0.9605 1 1 WCM677_Z7_1 12 81110946 133810855 −0.0092 0.01191.0113 1.0052 1 1 WCM677_Z7_1 13 19600515 40362489 −0.0708 −0.05030.9872 0.9443 1 1 WCM677_Z7_1 13 41133803 70535457 −1.0136 −1.0071 0.9930.0021 1 0 WCM677_Z7_1 13 70549886 115089411 −0.0535 −0.0328 0.99820.9568 1 1 WCM677_Z7_1 14 19377718 107283019 −0.0083 0.0128 1.00891.0089 1 1 WCM677_Z7_1 15 20170045 102517639 −0.4209 −0.4046 1.00580.5051 1 1 WCM677_Z7_1 16 67604 26147480 0.0243 0.0458 1.0395 1.0249 1 1WCM677_Z7_1 16 27078366 32013455 −0.9525 −0.9448 1.0327 0.0063 1 0WCM677_Z7_1 16 32077430 48643740 −0.0621 −0.0415 1.0158 0.9275 1 1WCM677_Z7_1 16 49193569 61935266 −0.9383 −0.9303 1.0489 6.00E−04 1 0WCM677_Z7_1 16 61935359 70211272 0.0337 0.0553 1.0391 1.0391 1 1WCM677_Z7_1 16 70255159 90233626 −0.9354 −0.9273 1.0457 0.006 1 0WCM677_Z7_1 17 131595 81083567 0.019 0.0404 1.0284 1.0284 1 1WCM677_Z7_1 18 48221 78005226 −0.0445 −0.0238 1.9675 −2.00E−04  2 0WCM677_Z7_1 19 281498 59083923 0.0227 0.0441 1.0352 1.0269 1 1WCM677_Z7_1 2 41614 116599858 −0.0328 −0.0119 1.0018 0.9817 1 1WCM677_Z7_1 2 118572428 144765055 −0.9926 −0.9857 1.0041 0.0059 1 0WCM677_Z7_1 2 144899591 147345860 −0.8787 −0.8696 NA NA NA NAWCM677_Z7_1 2 147346233 162567212 −0.0518 −0.0311 1.0044 0.953 1 1WCM677_Z7_1 2 162627511 189393878 −0.4759 −0.4603 0.9686 0.4851 1 0WCM677_Z7_1 2 189405938 218604233 −0.0679 −0.0474 0.9804 0.955 1 1WCM677_Z7_1 2 218620799 242946607 −0.956 −0.9483 1.036 5.00E−04 1 0WCM677_Z7_1 20 68406 33077679 −0.3884 −0.3716 1.0313 0.5145 1 1WCM677_Z7_1 20 33080320 33433235 −1.7355 −1.7481 NA NA NA NA WCM677_Z7_120 33437999 62904835 −0.3336 −0.3161 1.0562 0.5503 1 1 WCM677_Z7_1 219907301 48084210 −0.0069 0.0142 1.0181 1.0018 1 1 WCM677_Z7_1 2216287443 51215123 −0.6417 −0.6286 1.2906 0.003 1 0 WCM677_Z7_1 3 23934789499501 −0.0101 0.011 1.0077 1.0077 1 1 WCM677_Z7_1 3 89521648 976345360.4572 0.4823 NA NA NA NA WCM677_Z7_1 3 97655739 118878762 −1.045−1.0391 0.9704 0.0028 1 0 WCM677_Z7_1 3 118905658 197894713 0.52060.5462 1.941 0.9794 2 1 WCM677_Z7_1 4 59434 117220900 −0.0528 −0.03210.978 0.978 1 1 WCM677_Z7_1 4 118005573 135122340 −1.0805 −1.0754 0.9495−4.00E−04  1 0 WCM677_Z7_1 4 138442422 190426502 −0.0739 −0.0534 0.97240.9549 1 1 WCM677_Z7_1 5 140683 24537589 −0.4312 −0.415 0.9993 0.5007 11 WCM677_Z7_1 5 24593567 111496834 −0.0769 −0.0565 0.9771 0.946 1 1WCM677_Z7_1 5 111497290 180687803 0.2939 0.3177 1.5065 0.9863 2 1WCM677_Z7_1 6 203515 80201426 −0.4281 −0.4118 0.9817 0.5216 1 1WCM677_Z7_1 6 80203460 97001314 −0.9741 −0.9668 1.0198 0.0035 1 0WCM677_Z7_1 6 97051521 170893406 −0.4795 −0.464 0.9676 0.4824 1 0WCM677_Z7_1 7 193265 158937416 −0.0272 −0.0063 1.0027 0.9886 1 1WCM677_Z7_1 8 190908 43211998 −0.428 −0.4117 1.4983 0.0051 1 0WCM677_Z7_1 8 47752730 51465616 1.2928 1.3225 NA NA NA NA WCM677_Z7_1 851571151 66517769 0.9117 0.9397 3.827 0.0092 4 0 WCM677_Z7_1 8 66525560146279529 1.3912 1.4213 3.9041 1.4523 4 1 WCM677_Z7_1 9 17091 8733816−0.0472 −0.0265 1.0076 0.956 1 1 WCM677_Z7_1 9 12694081 14088237 −0.9355−0.9274 NA NA NA NA WCM677_Z7_1 9 14102457 103348634 −0.0288 −0.00791.0026 0.9865 1 1 WCM677_Z7_1 9 104032333 113013157 −0.5335 −0.51881.3905 0.0055 1 0 WCM677_Z7_1 9 113013683 141111414 0.3409 0.3651 1.52941.0465 2 1 WCM677_Z7_1 X 2707724 154509348 −0.0679 −0.0473 NA NA NA NAWCM677_Z9_1 1 721439 3809475 0.0581 0.0658 1.0635 1.0297 1 1 WCM677_Z9_11 3816750 18962816 −0.9563 −0.9629 1.0257 4.00E−04 1 0 WCM677_Z9_1 119018405 55551640 0.0149 0.0221 1.0155 1.0155 1 1 WCM677_Z9_1 1 55555353109159012 −0.0857 −0.0795 0.9627 0.9301 1 1 WCM677_Z9_1 1 109167290145115810 −0.0038 0.0033 1.1055 0.899 1 1 WCM677_Z9_1 1 145209432156568212 0.5853 0.5972 2.0153 1.0102 2 1 WCM677_Z9_1 1 156568774160254868 0.0149 0.0221 1.0319 0.999 1 1 WCM677_Z9_1 1 160259957249212373 0.5623 0.5741 1.9803 0.9971 2 1 WCM677_Z9_1 10 225995135440068 −0.0113 −0.0043 0.997 0.997 1 1 WCM677_Z9_1 11 193124103327014 0.0014 0.0085 1.0099 1.0018 1 1 WCM677_Z9_1 11 103339409126969232 −0.956 −0.9626 1.0259 4.00E−04 1 0 WCM677_Z9_1 11 128332352134856626 0.0132 0.0204 1.0409 0.9876 1 1 WCM677_Z9_1 12 148674 76325620.0389 0.0463 1.0504 1.0149 1 1 WCM677_Z9_1 12 7633843 8090972 −1.0598−1.0686 NA NA NA NA WCM677_Z9_1 12 8192459 8926041 0.2845 0.2941 NA NANA NA WCM677_Z9_1 12 8930225 9087073 −0.9295 −0.9356 NA NA NA NAWCM677_Z9_1 12 9087727 9465276 0.3365 0.3466 NA NA NA NA WCM677_Z9_1 129571646 15835866 −0.959 −0.9656 1.0227 0.0014 1 0 WCM677_Z9_1 1216035648 48073545 0.2598 0.2693 1.4859 0.9245 1 1 WCM677_Z9_1 1248075570 62946748 0.3628 0.3731 1.5026 1.0876 2 1 WCM677_Z9_1 1262949801 81101832 0.2671 0.2766 1.4422 0.9805 1 1 WCM677_Z9_1 1281102375 133810842 −0.0172 −0.0103 0.9929 0.9929 1 1 WCM677_Z9_1 1319600515 40362474 −0.0474 −0.0409 0.9799 0.9642 1 1 WCM677_Z9_1 1341133892 70535555 −1.0087 −1.0164 0.9887 0 1 0 WCM677_Z9_1 13 70549887115089411 −0.023 −0.0162 0.9928 0.9848 1 1 WCM677_Z9_1 14 19377726107283213 0.0027 0.0098 1.0068 1.0068 1 1 WCM677_Z9_1 15 20170006102517642 −0.4198 −0.4176 0.9937 0.5036 1 1 WCM677_Z9_1 16 6760427078374 0.0252 0.0325 1.03 1.0156 1 1 WCM677_Z9_1 16 27078548 32013471−0.9702 −0.9771 1.0158 3.00E−04 1 0 WCM677_Z9_1 16 32077478 48643776−0.0645 −0.058 0.9877 0.9334 1 1 WCM677_Z9_1 16 49193569 61935111−0.9608 −0.9675 1.0224 3.00E−04 1 0 WCM677_Z9_1 16 61935339 702112900.0416 0.049 1.0513 1.0179 1 1 WCM677_Z9_1 16 70255159 90233627 −0.9529−0.9594 1.0281 4.00E−04 1 0 WCM677_Z9_1 17 131595 81083561 0.0146 0.02181.0152 1.0152 1 1 WCM677_Z9_1 18 48203 78005199 −0.0266 −0.0198 1.9729−1.00E−04  2 0 WCM677_Z9_1 19 281415 59083985 0.0041 0.0112 1.01181.0037 1 1 WCM677_Z9_1 2 41612 116573267 −0.0156 −0.0087 1.001 0.987 1 1WCM677_Z9_1 2 116593754 145271267 −0.9766 −0.9836 1.0112 2.00E−04 1 0WCM677_Z9_1 2 145274869 162567203 −0.0351 −0.0284 1.0043 0.9568 1 1WCM677_Z9_1 2 162627550 188211112 −0.4407 −0.4388 0.9898 0.4857 1 0WCM677_Z9_1 2 188216855 207656422 −0.0345 −0.0278 1.0166 0.9453 1 1WCM677_Z9_1 2 207814367 208485372 −1.0114 −1.0191 NA NA NA NAWCM677_Z9_1 2 208486562 218604289 −0.0296 −0.0228 1.0211 0.9475 1 1WCM677_Z9_1 2 218620790 242946616 −0.9368 −0.943 1.0398 5.00E−04 1 0WCM677_Z9_1 20 68351 31383283 −0.4083 −0.406 1.0086 0.5008 1 1WCM677_Z9_1 20 31383484 33077692 −0.2456 −0.2412 NA NA NA NA WCM677_Z9_120 33080320 33370121 −1.7932 −1.8224 NA NA NA NA WCM677_Z9_1 20 3343329449621339 −0.2992 −0.2954 1.0714 0.5583 1 1 WCM677_Z9_1 20 4962631462904863 −0.3824 −0.3798 1.0247 0.5124 1 1 WCM677_Z9_1 21 990731848084282 −0.0056 0.0014 1.0101 0.9919 1 1 WCM677_Z9_1 22 1628743951215115 −0.5432 −0.5428 1.3691 0.0038 1 0 WCM677_Z9_1 3 239347 97634561−2.00E−04 0.0068 1.0088 1.0007 1 1 WCM677_Z9_1 3 97655720 118865604−0.991 −0.9983 1.0011 1.00E−04 1 0 WCM677_Z9_1 3 118865801 1978947260.5416 0.5532 1.9549 0.9798 2 1 WCM677_Z9_1 4 59326 117220908 −0.0334−0.0267 0.9817 0.9817 1 1 WCM677_Z9_1 4 118005614 135122242 −1.0209−1.0289 0.9803 −1.00E−04  1 0 WCM677_Z9_1 4 138442429 190426502 −0.0625−0.0561 0.9697 0.9541 1 1 WCM677_Z9_1 5 140436 24593567 −0.4014 −0.3990.9759 0.5409 1 1 WCM677_Z9_1 5 26881275 110843047 −0.0569 −0.05050.9783 0.9529 1 1 WCM677_Z9_1 5 111013695 180687776 0.312 0.3219 1.49691.003 1 1 WCM677_Z9_1 6 203542 80222917 −0.4018 −0.3994 1.0101 0.5062 11 WCM677_Z9_1 6 80223223 92231400 −0.992 −0.9994 1.0003 1.00E−04 1 0WCM677_Z9_1 6 93953172 170893438 −0.46 −0.4584 0.9713 0.4843 1 0WCM677_Z9_1 7 193265 158937416 −0.0045 0.0025 1.0078 0.9957 1 1WCM677_Z9_1 8 190908 43212019 −0.4114 −0.4091 1.5086 −0.0025 2 0WCM677_Z9_1 8 47752745 51465617 1.3881 1.4041 NA NA NA NA WCM677_Z9_1 851571149 65509244 0.9353 0.9492 3.8524 0.0093 4 0 WCM677_Z9_1 8 65517340146279489 1.411 1.427 3.917 1.4609 4 1 WCM677_Z9_1 9 17116 8733795−0.0505 −0.044 1.0278 0.9121 1 1 WCM677_Z9_1 9 12694236 14088271 −1.0484−1.0569 NA NA NA NA WCM677_Z9_1 9 14102457 103348634 −0.0107 −0.00371.0126 0.9823 1 1 WCM677_Z9_1 9 104032203 112969822 −0.4759 −0.47461.4349 0.0045 1 0 WCM677_Z9_1 9 113006491 141111414 0.3449 0.355 1.51881.0392 2 1 WCM677_Z9_1 X 2707711 154509348 −0.0567 −0.0502 NA NA NA NAWCM6_Z5_1 1 809582 51180660 −0.2943 0.6039 2.014 1.0257 2 1 WCM6_Z5_1 151210433 62299351 0.0701 0.9916 2.9941 0.9827 3 1 WCM6_Z5_1 1 6232178272748079 0.3301 1.2649 2.8431 1.9631 3 2 WCM6_Z5_1 1 74492587 104163135−0.8472  9.00E−04 1.9634 0.0379 2 0 WCM6_Z5_1 1 107599703 2492123410.3592 1.2953 2.9469 1.9618 3 2 WCM6_Z5_1 10 255895 8115989 −0.8853−0.0415 1.8562 0.087 2 0 WCM6_Z5_1 10 11060033 18331789 1.0374 1.99786.2188 1.769 6 2 WCM6_Z5_1 10 18430123 18803448 0.6107 1.5573 NA NA NANA WCM6_Z5_1 10 18803989 18962937 0.3624 1.2987 NA NA NA NA WCM6_Z5_1 1018964170 21435454 −0.7912 0.063 NA NA NA NA WCM6_Z5_1 10 2146133822856835 0.3448 1.2803 NA NA NA NA WCM6_Z5_1 10 22862202 28908551 0.6361.5835 4.0101 1.9837 4 2 WCM6_Z5_1 10 28966936 38650270 −0.8943 −0.05161.8956 0.0341 2 0 WCM6_Z5_1 10 38654529 46962074 0.3743 1.3111 2.80272.1598 3 2 WCM6_Z5_1 10 46963813 49687666 −0.7215 0.1399 NA NA NA NAWCM6_Z5_1 10 49791169 53059393 0.2041 1.1328 NA NA NA NA WCM6_Z5_1 1053227568 61122203 −0.5523 0.325 NA NA NA NA WCM6_Z5_1 10 6141261464575610 0.1842 1.1119 NA NA NA NA WCM6_Z5_1 10 64893248 69106445−0.7002 0.1633 NA NA NA NA WCM6_Z5_1 10 69281686 70405593 0.5914 1.53723.8243 1.9802 4 2 WCM6_Z5_1 10 70406062 71921623 0.0653 0.9866 2.11961.8434 2 2 WCM6_Z5_1 10 71964679 75277538 0.6375 1.585 3.8931 2.1072 4 2WCM6_Z5_1 10 75279549 82369257 1.2772 2.2438 7.4413 2.0315 7 2 WCM6_Z5_110 83635291 88260290 0.0998 1.0231 NA NA NA NA WCM6_Z5_1 10 88277518135440062 −0.8439 0.0045 1.9481 0.0583 2 0 WCM6_Z5_1 11 193112 65268919−0.3324 0.563 1.9586 0.996 2 1 WCM6_Z5_1 11 65269375 78467874 0.06270.9839 1.9966 1.959 2 2 WCM6_Z5_1 11 78481998 134257515 −0.3208 0.57541.9849 0.9953 2 1 WCM6_Z5_1 12 283766 78583891 0.0379 0.9576 1.95441.9298 2 2 WCM6_Z5_1 12 78591073 81839440 −0.3757 0.5164 2.0408 0.82 2 1WCM6_Z5_1 12 81851545 114793866 0.0339 0.9534 1.9712 1.9016 2 2WCM6_Z5_1 12 114804034 115120914 −0.9246 −0.0853 NA NA NA NA WCM6_Z5_112 116399206 133779169 0.0559 0.9766 1.9928 1.9429 2 2 WCM6_Z5_1 1319747994 24243145 1.07 2.0314 7.3547 0.8211 7 1 WCM6_Z5_1 13 2430455041949696 −0.3365 0.5586 1.9353 1.0103 2 1 WCM6_Z5_1 13 42032482 75860900−1.5814 −0.8437 1.0411 0.0733 1 0 WCM6_Z5_1 13 75863089 115089411−0.3248 0.5711 1.944 1.0274 2 1 WCM6_Z5_1 14 19377685 107283026 0.04040.9602 1.96 1.9312 2 2 WCM6_Z5_1 15 20170045 40510711 −0.7084 0.15441.2978 0.9281 1 1 WCM6_Z5_1 15 40512943 40920783 −1.5851 −0.8482 NA NANA NA WCM6_Z5_1 15 40921518 43426191 −0.6971 0.1667 1.3815 0.8634 1 1WCM6_Z5_1 15 43426454 43940187 −1.4988 −0.7453 1.0891 0.104 1 0WCM6_Z5_1 15 43988604 102514154 −0.7073 0.1555 1.2583 0.9693 1 1WCM6_Z5_1 16 79914 11370138 0.0429 0.9629 1.974 1.9246 2 2 WCM6_Z5_1 1611374866 12142278 −0.8772 −0.0325 NA NA NA NA WCM6_Z5_1 16 1214586018903605 −8.00E−04 0.9167 1.9237 1.8518 2 2 WCM6_Z5_1 16 1902045819562544 −0.8397 0.0092 NA NA NA NA WCM6_Z5_1 16 19576164 20781523−3.2602 −3.3564 NA NA NA NA WCM6_Z5_1 16 20787375 21128601 −0.75690.1009 NA NA NA NA WCM6_Z5_1 16 21132099 57007445 0.057 0.9778 1.98611.9528 2 2 WCM6_Z5_1 16 57012086 90161530 −0.8239 0.0268 1.9983 0.0392 20 WCM6_Z5_1 17 131595 19186977 −0.3352 0.56 1.9325 1.0161 2 1 WCM6_Z5_117 19188994 81052298 0.3371 1.2722 2.8802 1.9504 3 2 WCM6_Z5_1 18 4766957026471 −0.8323 0.0174 1.1031 0.9212 1 1 WCM6_Z5_1 18 57103214 78005224−1.5838 −0.8466 1.0712 0.041 1 0 WCM6_Z5_1 19 281534 1506220 0.00840.9264 1.9408 1.8603 2 2 WCM6_Z5_1 19 1506286 3028766 −0.7736 0.08242.0696 0.048 2 0 WCM6_Z5_1 19 3053838 3118983 −3.0698 −2.9762 NA NA NANA WCM6_Z5_1 19 3136470 4366925 −0.7922 0.0619 2.0786 0.009 2 0WCM6_Z5_1 19 4402786 17750672 0.058 0.9789 1.9876 1.9543 2 2 WCM6_Z5_119 17751398 17932138 −0.8689 −0.0232 NA NA NA NA WCM6_Z5_1 19 1793758842636501 0.0381 0.9579 1.9733 1.9116 2 2 WCM6_Z5_1 19 42703764 48018114−0.8439 0.0045 1.9781 0.0282 2 0 WCM6_Z5_1 19 48176904 59082615 0.04030.9601 1.9661 1.9249 2 2 WCM6_Z5_1 2 41602 33811712 −0.3057 0.59171.9536 1.0604 2 1 WCM6_Z5_1 2 33813495 80846314 −0.8254 0.0251 1.16770.8674 1 1 WCM6_Z5_1 2 80874686 125504906 −0.3278 0.5679 1.962 1.0027 21 WCM6_Z5_1 2 125521391 144709545 −0.8101 0.0421 1.138 0.9212 1 1WCM6_Z5_1 2 144710346 242815257 −0.3123 0.5846 1.9941 1.0051 2 1WCM6_Z5_1 20 68413 947801 0.058 0.9789 2.0147 1.9272 2 2 WCM6_Z5_1 20948665 23967268 −0.2462 0.6554 2.1552 0.995 2 1 WCM6_Z5_1 20 2452378162904982 0.1061 1.0296 2.0673 2.0157 2 2 WCM6_Z5_1 21 10862853 480842810.0299 0.9492 1.9512 1.9104 2 2 WCM6_Z5_1 22 16287704 51215123 −0.77550.0803 2.0725 0.0419 2 0 WCM6_Z5_1 3 361501 96533521 0.6032 1.54953.9175 1.9366 4 2 WCM6_Z5_1 3 96533819 98311874 0.9653 1.9237 4.12193.4658 4 3 WCM6_Z5_1 3 98312138 140140107 0.5919 1.5377 3.889 1.9176 4 2WCM6_Z5_1 3 140167508 140284912 −0.6298 0.2406 NA NA NA NA WCM6_Z5_1 3140397256 197847250 0.5823 1.5277 3.8715 1.8952 4 2 WCM6_Z5_1 4 53361166418697 0.0421 0.9621 1.9625 1.9337 2 2 WCM6_Z5_1 4 166795070169602489 0.5216 1.4647 NA NA NA NA WCM6_Z5_1 4 169604196 1890683900.0611 0.9822 2.0151 1.9358 2 2 WCM6_Z5_1 5 140568 83550040 −0.34260.552 1.9866 0.9456 2 1 WCM6_Z5_1 5 83680098 98195745 −0.8613 −0.01481.9684 0.0111 2 0 WCM6_Z5_1 5 98209377 108168579 −2.9332 −2.7299 NA NANA NA WCM6_Z5_1 5 108203574 122012328 −0.8485 −6.00E−04 1.9526 0.0466 20 WCM6_Z5_1 5 122110904 151230962 −0.3179 0.5785 1.9506 1.036 2 1WCM6_Z5_1 5 151234644 161580404 −0.816 0.0355 1.9565 0.0934 2 0WCM6_Z5_1 5 162866423 169812455 −0.3955 0.4951 2.0951 0.7236 2 1WCM6_Z5_1 5 169931570 180687824 0.0522 0.9727 1.9895 1.9356 2 2WCM6_Z5_1 6 292582 57512678 0.0495 0.9699 1.9918 1.9256 2 2 WCM6_Z5_1 662390958 102483365 −0.8242 0.0264 2.0103 0.0267 2 0 WCM6_Z5_1 6102483435 129571329 −1.5713 −0.8317 1.0848 0.039 1 0 WCM6_Z5_1 6129573432 138734011 −0.3215 0.5747 1.8959 1.0828 2 1 WCM6_Z5_1 6139094822 170893408 0.0383 0.958 1.9632 1.9221 2 2 WCM6_Z5_1 7 19371728610032 0.357 1.293 2.8884 2.0124 3 2 WCM6_Z5_1 7 28725796 39612224−0.8555 −0.0083 1.957 0.0315 2 0 WCM6_Z5_1 7 39726346 76071147 0.35821.2943 2.9729 1.9321 3 2 WCM6_Z5_1 7 76109950 82595650 1.3846 2.35367.2571 2.9646 7 3 WCM6_Z5_1 7 82763817 87856203 −0.3344 0.5609 2.94880.0015 3 0 WCM6_Z5_1 7 87908920 158937416 0.0561 0.9768 2.8809 1.0553 31 WCM6_Z5_1 8 190928 1514009 0.1715 1.0985 NA NA NA NA WCM6_Z5_1 81574933 3611497 0.0373 0.957 NA NA NA NA WCM6_Z5_1 8 3855632 33354233−0.8141 0.0376 2.0263 0.0265 2 0 WCM6_Z5_1 8 33356074 33454885 −0.74910.1095 NA NA NA NA WCM6_Z5_1 8 35406917 40011362 0.1185 1.0427 2.21851.9015 2 2 WCM6_Z5_1 8 40389730 42857247 −0.6946 0.1695 2.201 0.0483 2 0WCM6_Z5_1 8 42862997 146279472 1.2828 2.2495 7.3585 2.1517 7 2 WCM6_Z5_19 17044 71152313 0.0428 0.9628 1.9739 1.9244 2 2 WCM6_Z5_1 9 71155621141071320 0.3502 1.2859 2.9074 1.9692 3 2 WCM6_Z5_1 X 2707687 579365410.5524 1.4967 NA NA NA NA WCM6_Z5_1 X 62898360 69282554 1.5282 2.5002 NANA NA NA WCM6_Z5_1 X 69282680 154509348 0.5528 1.4971 NA NA NA NA WCM7 114930 1149126 0.0356 0.155 1.3231 0.9038 1 1 WCM7 1 1149559 145475378−0.1576 −0.9167 0.6153 0.4441 1 0 WCM7 1 145487375 249214028 0.05090.2182 1.1633 1.1633 1 1 WCM7 10 226048 55943305 0.0295 0.1295 1.09391.0939 1 1 WCM7 10 55943429 96466633 −0.1856 −1.1479 0.5112 0.3913 1 0WCM7 10 96466720 135477891 0.0499 0.2142 1.16 1.16 1 1 WCM7 11 193096134605916 0.0509 0.2183 1.1633 1.1633 1 1 WCM7 12 148468 1338108680.0361 0.1571 1.115 1.115 1 1 WCM7 13 19042044 115089411 −0.1923 −1.20830.5123 0.3532 1 0 WCM7 14 19110239 107283274 0.0291 0.1276 1.0925 1.09251 1 WCM7 15 20083896 102515245 −0.1566 −0.9092 0.614 0.4509 1 0 WCM7 1666894 304514 −0.1045 −0.5513 NA NA NA NA WCM7 16 304684 50248191 0.03530.1539 1.1126 1.1126 1 1 WCM7 16 50250043 90260461 −0.1578 −0.91890.6104 0.4474 1 0 WCM7 17 131595 81187839 0.021 0.093 1.0666 1.0666 1 1WCM7 18 47824 23969850 0.0185 0.0822 1.0586 1.0586 1 1 WCM7 18 2397002774593283 −0.1749 −1.0558 0.5575 0.4045 1 0 WCM7 18 74611127 78005281−0.0644 −0.3191 0.8015 0.8015 1 1 WCM7 19 105041 59093696 0.0422 0.18251.1349 1.1349 1 1 WCM7 2 41583 243037022 0.038 0.1654 2.2415 0.0014 2 0WCM7 20 68337 62934592 0.0419 0.1813 1.1339 1.1339 1 1 WCM7 21 959031148084201 −0.0149 −0.0688 0.9534 0.9534 1 1 WCM7 22 16159068 51219129−0.1497 −0.8572 0.6381 0.466 1 0 WCM7 3 239531 131254111 0.0441 0.19041.1411 1.1411 1 1 WCM7 3 131261473 197896660 0.2049 0.76 1.6935 1.6935 22 WCM7 4 53378 40763142 −0.1887 −1.1752 0.5226 0.3631 1 0 WCM7 440776459 190904471 0.0101 0.0451 1.0318 1.0318 1 1 WCM7 5 90714 524043120.1678 0.6421 1.5606 1.5606 2 2 WCM7 5 52404546 133996832 −0.0597−0.2937 1.4395 0.1922 1 0 WCM7 5 133997136 180687821 0.1527 0.592 1.50741.5074 2 2 WCM7 6 203542 63939127 0.0296 0.1298 1.0941 1.0941 1 1 WCM7 663939458 170892848 −0.1832 −1.1267 0.538 0.3779 1 0 WCM7 7 195638158937022 0.2098 0.7752 1.7115 1.7115 2 2 WCM7 8 163476 36642059 −0.1584−0.923 0.6089 0.446 1 0 WCM7 8 36644852 48689573 0.0347 0.1516 1.11081.1108 1 1 WCM7 8 48690265 125339650 0.2148 0.7905 1.7297 1.7297 2 2WCM7 8 125342947 145737040 0.0917 0.3767 1.2984 1.2984 1 1 WCM7 8145737286 146279332 −0.0114 −0.0524 1.0726 0.8561 1 1 WCM7 9 1590815267878 0.0475 0.2044 1.1522 1.1522 1 1 WCM7 9 15307171 27949716−0.1449 −0.8221 0.652 0.4793 1 0 WCM7 9 27949961 141107539 0.0505 0.21671.1621 1.1621 1 1 WCM7 X 2700084 154493601 0.048 0.2063 NA NA NA NAWCM73 1 17483 249213964 0.0272 0.8473 1.7992 1.7992 2 2 WCM73 10 225914135438935 0 0.2175 1.1627 1.1627 1 1 WCM73 11 193096 134605906 0.00830.4386 1.3553 1.3553 1 1 WCM73 12 148417 133810752 −1.00E−04 0.21461.1603 1.1603 1 1 WCM73 13 19041979 115089411 −0.0258 −0.8169 0.56760.5676 1 1 WCM73 14 19110239 107283263 −0.0532 NA −0.0496 −0.0496 0 0WCM73 15 20083896 102514227 0.0306 0.91 1.879 1.879 2 2 WCM73 16 6760490168701 −0.0286 −0.9847 0.5053 0.5053 1 1 WCM73 17 131595 81187925 2.00E−04 0.2232 1.1673 1.1673 1 1 WCM73 18 47684 78005224 −0.0611 NA−0.2263 −0.2263 0 0 WCM73 19 104963 59093645 −0.0304 −1.1122 0.46260.4626 0 0 WCM73 2 41509 243036990 0.0075 0.4195 1.3375 1.3375 1 1 WCM7320 68373 62934623 0.014 0.575 1.4897 1.4897 1 1 WCM73 21 959031148084136 0.0079 0.4288 1.3461 1.3461 1 1 WCM73 22 16159016 512190900.0081 0.4326 1.3497 1.3497 1 1 WCM73 3 239530 197896818 −0.0026 0.1411.1027 1.1027 1 1 WCM73 4 53363 190903980 −0.0106 −0.126 0.9164 0.9164 11 WCM73 5 90697 180687818 −0.0218 −0.6023 0.6587 0.6587 1 1 WCM73 6203369 170892848 −0.0217 −0.5953 0.6619 0.6619 1 1 WCM73 7 193253158937011 −0.0089 −0.066 0.9553 0.9553 1 1 WCM73 8 163476 146279423−0.0283 −0.9661 0.5119 0.5119 1 1 WCM73 9 14884 141107514 0.0089 0.45471.3705 1.3705 1 1 WCM73 X 2700189 154493484 −0.2189 NA NA NA NA NAWCM73_X1_1 1 69590 26644555 0.0166 0.0272 1.0449 0.9931 1 1 WCM73_X1_1 126646717 27744862 −0.2484 −0.8983 NA NA NA NA WCM73_X1_1 1 27745553249212420 0.0199 0.0366 1.043 1.0084 1 1 WCM73_X1_1 10 225958 1354401080.0091 0.0059 1.0041 1.0041 1 1 WCM73_X1_1 11 193127 2016825 0.03620.0819 1.6095 0.5074 2 1 WCM73_X1_1 11 2017128 3381034 −0.1958 −0.67720.8016 0.4491 1 0 WCM73_X1_1 11 3381337 134856603 0.0272 0.0568 1.04021.0402 1 1 WCM73_X1_1 12 148811 133810842 0.0239 0.0478 1.0424 1.025 1 1WCM73_X1_1 13 19600364 115089411 −0.0157 −0.0657 1.0061 0.9049 1 1WCM73_X1_1 14 19377716 55903285 0.0072  7.00E−04 1.0319 0.9691 1 1WCM73_X1_1 14 55903640 79117616 −0.2514 −0.912 1.0569 0.006 1 0WCM73_X1_1 14 79175749 107283091 −0.0147 −0.0627 1.0081 0.9068 1 1WCM73_X1_1 15 20170036 102517666 −0.0596 −0.1992 0.9011 0.841 1 1WCM73_X1_1 16 67604 50060368 0.02 0.0369 1.0259 1.0259 1 1 WCM73_X1_1 1650063666 55559524 −0.2502 −0.9065 1.1694 −0.1024 1 0 WCM73_X1_1 1655562359 79633459 0.023 0.0452 1.0578 1.0058 1 1 WCM73_X1_1 16 7963379790233622 −0.2105 −0.7366 1.0203 0.1799 1 0 WCM73_X1_1 17 131595 81083567−0.0011 −0.0231 1.0097 0.9585 1 1 WCM73_X1_1 18 48224 78005224 −0.2295−0.8162 1.0578 0.0781 1 0 WCM73_X1_1 19 281507 1149368 0.0352 0.07921.0943 1.0186 1 1 WCM73_X1_1 19 1154193 3902518 −0.1405 −0.4692 1.07830.3664 1 0 WCM73_X1_1 19 3905633 11364354 0.0201 0.0371 1.0433 1.0087 11 WCM73_X1_1 19 11373088 13054676 −0.274 −1.0166 1.0045 −0.016 1 0WCM73_X1_1 19 13056799 59083929 −0.0246 −0.0922 0.9661 0.9101 1 1WCM73_X1_1 2 41613 1312299 −0.1101 −0.3635 NA NA NA NA WCM73_X1_1 21320143 96781886  2.00E−04 −0.0196 0.9865 0.9865 1 1 WCM73_X1_1 296789787 232790241 −7.00E−04 −0.0221 1.9112 0.0583 2 0 WCM73_X1_1 2232879652 233995353 −0.4741 −2.3971 NA NA NA NA WCM73_X1_1 2 233995535242946607 −6.00E−04 −0.0218 1.9315 0.0386 2 0 WCM73_X1_1 20 6835162904835 −0.005 −0.0347 1.0074 0.9451 1 1 WCM73_X1_1 21 9907279 48084277−0.0933 −0.3075 0.848 0.7681 1 1 WCM73_X1_1 22 16287431 51219138 −0.0177−0.0718 0.9711 0.9318 1 1 WCM73_X1_1 3 239347 141644446 0.0263 0.05451.0559 1.0211 1 1 WCM73_X1_1 3 141671431 146303867 −0.2568 −0.9362 NA NANA NA WCM73_X1_1 3 146307533 197894712 0.0256 0.0524 1.0717 1.0023 1 1WCM73_X1_1 4 59331 190426502 −0.0286 −0.1042 0.9526 0.908 1 1 WCM73_X1_15 140560 54252345 0.0252 0.0513 1.1056 0.9667 1 1 WCM73_X1_1 5 5425358179949874 −0.1838 −0.6302 1.0716 0.2205 1 0 WCM73_X1_1 5 79950403180687773 0.0276 0.0581 1.0643 1.0179 1 1 WCM73_X1_1 6 203699 170893661−0.0185 −0.0742 0.9667 0.9331 1 1 WCM73_X1_1 7 193253 149133916 0.01790.0309 1.0648 0.9784 1 1 WCM73_X1_1 7 149148163 155604655 −0.2271−0.8056 1.0774 0.0668 1 0 WCM73_X1_1 7 155748043 158937142 0.0226 0.0441.0858 0.9761 1 1 WCM73_X1_1 8 190900 24251645 −0.2372 −0.849 1.1317−0.0214 1 0 WCM73_X1_1 8 24253290 28420320 0.011 0.0115 1.0567 0.9593 11 WCM73_X1_1 8 28573760 104417045 −0.0504 −0.1705 0.9379 0.8391 1 1WCM73_X1_1 8 104420009 146279489 0.0323 0.071 1.0766 1.0243 1 1WCM73_X1_1 9 17055 134385788 0.0259 0.0533 1.055 1.0203 1 1 WCM73_X1_1 9134386759 137309131 −0.2653 −0.9757 1.0573 −0.0403 1 0 WCM73_X1_1 9137313635 141111414 0.0059 −0.0031 1.0264 0.9693 1 1 WCM73_X1_1 X2707682 154509348 −0.0081 −0.0434 NA NA NA NA WCM78 1 14930 898735−0.089 −0.477 NA NA NA NA WCM78 1 898872 16804753 0.0787 0.4527 1.36861.3686 1 1 WCM78 1 16804965 150040828 −0.041 −0.1568 0.897 0.897 1 1WCM78 1 150044243 152127631 0.4244 1.5718 4.3279 1.6177 4 2 WCM78 1152127741 249213973 −0.0212 −0.0407 0.9722 0.9722 1 1 WCM78 10 225914106153158 −0.0554 −0.2467 0.8428 0.8428 1 1 WCM78 10 106153254 1354389550.0995 0.5406 1.4546 1.4546 1 1 WCM78 11 193096 62291779 0.0111 0.1341.103 1.0917 1 1 WCM78 11 62292063 62678147 −0.2651 −3.1533 0.16840.0564 0 0 WCM78 11 62678512 134320624 0.0403 0.2787 1.2131 1.2131 1 1WCM78 12 148444 310983 0.0868 0.4874 NA NA NA NA WCM78 12 31202131254752 0.2886 1.1995 2.2965 2.2965 2 2 WCM78 12 31255238 571461220.0547 0.3461 1.2711 1.2711 1 1 WCM78 12 57167649 62768361 0.3208 1.29343.46 1.4421 3 1 WCM78 12 62775413 116413409 0.1037 0.5581 1.4723 1.47231 1 WCM78 12 116418505 122208890 0.4356 1.5999 4.4576 1.605 4 2 WCM78 12122209503 133810703 −0.066 −0.3158 0.9534 0.6533 1 1 WCM78 13 19042044109282133 −0.0264 −0.0702 0.9525 0.9525 1 1 WCM78 13 109311775 1113401170.3559 1.3917 2.6239 2.6239 3 3 WCM78 13 111340386 115089411 0.00310.0928 1.0664 1.0664 1 1 WCM78 14 19110378 22038268 −0.0431 −0.16990.8889 0.8889 1 1 WCM78 14 22038456 24114450 0.3544 1.3876 3.8571 1.37564 1 WCM78 14 24403717 107283266 0.0037 0.0955 1.0684 1.0684 1 1 WCM78 1520083896 102506273 0.017 0.1644 1.1207 1.1207 1 1 WCM78 16 64423 740365−0.0166 −0.0148 1.0841 0.8955 1 1 WCM78 16 742668 2474346 0.1551 0.75761.8281 1.5533 2 2 WCM78 16 2474680 90168855 −0.0344 −0.1173 0.92190.9219 1 1 WCM78 17 131595 6913781 −0.0544 −0.2406 0.8464 0.8464 1 1WCM78 17 6915497 8132135 −0.3084 NA 0.0061 −0.0573 0 0 WCM78 17 813248981187834 0.0096 0.1264 1.0916 1.0916 1 1 WCM78 18 47804 78005210 0.00420.0985 1.0707 1.0707 1 1 WCM78 19 105021 2901091 −0.1677 −1.1887 0.53860.3388 1 0 WCM78 19 2915598 5215310 0.1654 0.7955 1.742 1.7294 2 2 WCM7819 5215558 50453416 −0.0295 −0.0883 0.9406 0.9406 1 1 WCM78 19 5045517752505036 0.26 1.1123 3.1292 1.1946 3 1 WCM78 19 52505463 59093645−0.0488 −0.2051 0.8675 0.8675 1 1 WCM78 2 41662 3628529 −0.0984 −0.54760.6842 0.6842 1 1 WCM78 2 3651221 204736155 0.0057 0.1064 1.0765 1.07651 1 WCM78 2 204737487 243037022 −0.1058 −0.6049 0.6575 0.6575 1 1 WCM7820 68336 62934572 −0.0554 −0.247 0.8427 0.8427 1 1 WCM78 21 959027148084214 −0.017 −0.0169 0.9883 0.9883 1 1 WCM78 22 16159005 51219138−0.0123 0.0094 1.0066 1.0066 1 1 WCM78 3 239524 65940205 0.004 0.09711.0697 1.0697 1 1 WCM78 3 66017711 69435184 0.4374 1.6046 3.4437 2.63853 3 WCM78 3 69788724 197896683 −0.0061 0.0434 1.0305 1.0305 1 1 WCM78 453418 70823000 −0.0333 −0.1109 0.926 0.926 1 1 WCM78 4 70823265 748538900.2043 0.9316 2.0431 1.7717 2 2 WCM78 4 74861637 190904482 −0.0369−0.1319 0.9126 0.9126 1 1 WCM78 5 90680 180687803 −0.031 −0.0971 0.93490.9349 1 1 WCM78 6 203535 27806861 −0.0602 −0.2779 0.8248 0.8248 1 1WCM78 6 27809368 32007956 0.1912 0.8868 3.0404 0.6578 3 1 WCM78 632016415 144869844 0.0236 0.1976 1.1468 1.1468 1 1 WCM78 6 144870019148872433 0.1797 0.8467 2.2241 1.3727 2 1 WCM78 6 148872898 170892848−0.0862 −0.456 0.729 0.729 1 1 WCM78 7 193222 30066104 0.1529 0.74971.6814 1.6814 2 2 WCM78 7 30084684 33014377 0.4277 1.5803 4.522 1.4584 51 WCM78 7 33014963 49951754 0.1465 0.7257 1.6599 1.6475 2 2 WCM78 749952114 148113783 0.0175 0.1667 1.1282 1.1168 1 1 WCM78 7 148114529151064006 0.3048 1.2473 2.5611 2.1869 3 2 WCM78 7 151064228 158937227−0.1296 −0.8056 0.8285 0.3157 1 0 WCM78 8 163470 99208130 −0.0094 0.02541.0178 1.0178 1 1 WCM78 8 99215285 126163426 0.1389 0.6969 1.6211 1.62112 2 WCM78 8 126194510 128098838 0.0054 0.1046 NA NA NA NA WCM78 8128428061 146003567 0.3996 1.5082 3.8806 1.8085 4 2 WCM78 8 146005624146279431 0.1378 0.6928 2.32 0.9128 2 1 WCM78 9 14887 141107545 −0.00690.0391 1.0275 1.0275 1 1 WCM78 X 2700151 11072078 −0.0392 −0.1456 NA NANA NA WCM78 X 11072297 29414436 0.3165 1.281 NA NA NA NA WCM78 X29417363 133304174 −0.0265 −0.0707 NA NA NA NA WCM78 X 133372863134126394 0.7069 2.202 NA NA NA NA WCM78 X 134155927 154493585 −0.0652−0.3108 NA NA NA NA WCM78_Z1_1 1 721439 878434 −0.0261 0.148 NA NA NA NAWCM78_Z1_1 1 878716 2938265 0.2213 0.5018 1.8889 0.943 2 1 WCM78_Z1_1 12938692 16578147 0.0481 0.2569 1.4012 0.9887 1 1 WCM78_Z1_1 1 1657886329652156 −0.1607 −0.0568 0.9794 0.9434 1 1 WCM78_Z1_1 1 2969623035579769 0.0981 0.3289 1.554 0.9582 2 1 WCM78_Z1_1 1 35580079 39466695−0.1556 −0.049 1.1216 0.8116 1 1 WCM78_Z1_1 1 39469068 40211140 0.18250.4481 NA NA NA NA WCM78_Z1_1 1 40214692 65068566 −0.1462 −0.0344 1.00070.9522 1 1 WCM78_Z1_1 1 65095077 67891937 0.224 0.5055 NA NA NA NAWCM78_Z1_1 1 67895918 116380979 −0.1388 −0.0228 1.0148 0.9539 1 1WCM78_Z1_1 1 116519280 118166515 0.2828 0.586 2.011 0.9912 2 1WCM78_Z1_1 1 118413224 149877566 −0.077 0.0716 1.3831 0.7187 1 1WCM78_Z1_1 1 149878293 152129173 0.9724 1.46 4.7742 0.728 5 1 WCM78_Z1_11 152129428 154698440 −0.1665 −0.0659 0.9897 0.921 1 1 WCM78_Z1_1 1154709546 155172907 0.2163 0.495 NA NA NA NA WCM78_Z1_1 1 155173301196197439 −0.1074 0.0255 1.052 0.9836 1 1 WCM78_Z1_1 1 196205140203472834 0.0844 0.3093 1.5093 0.9689 2 1 WCM78_Z1_1 1 203652473204588916 0.4525 0.812 NA NA NA NA WCM78_Z1_1 1 204589072 2077581760.0284 0.2283 1.3116 1.0312 1 1 WCM78_Z1_1 1 207760874 211093346 −0.2016−0.1212 0.9967 0.8421 1 1 WCM78_Z1_1 1 211192166 212798977 0.2027 0.4761NA NA NA NA WCM78_Z1_1 1 212799330 241094033 −0.2047 −0.126 0.93230.9003 1 1 WCM78_Z1_1 1 241099999 243327896 0.165 0.4235 NA NA NA NAWCM78_Z1_1 1 243328842 249212434 −0.1909 −0.1043 0.9508 0.9097 1 1WCM78_Z1_1 10 225952 19612972 −0.4025 −0.4542 0.9696 0.4902 1 0WCM78_Z1_1 10 19616498 69792546 −0.1308 −0.0105 1.0142 0.9713 1 1WCM78_Z1_1 10 69793903 70922249 0.2354 0.5213 NA NA NA NA WCM78_Z1_1 1070925853 106960956 −0.1444 −0.0315 0.983 0.9739 1 1 WCM78_Z1_1 10106970952 107022174 0.0544 0.266 NA NA NA NA WCM78_Z1_1 10 108337227119302836 0.2792 0.5812 1.7768 1.2153 2 1 WCM78_Z1_1 10 119303155135346340 0.0502 0.2599 1.3744 1.0203 1 1 WCM78_Z1_1 10 135347380135440090 −0.0345 0.1355 NA NA NA NA WCM78_Z1_1 11 193127 2016741−0.1689 −0.0696 1.2154 0.6904 1 1 WCM78_Z1_1 11 2017122 2591932 0.24750.5379 NA NA NA NA WCM78_Z1_1 11 2592619 4621764 −0.0813 0.0652 1.12860.9638 1 1 WCM78_Z1_1 11 4622015 5323171 0.2988 0.6078 2.1034 0.9444 2 1WCM78_Z1_1 11 5344907 46625353 −0.1367 −0.0196 1.0094 0.9637 1 1WCM78_Z1_1 11 46637197 48328695 0.3661 0.6981 NA NA NA NA WCM78_Z1_1 1148346681 63766449 −0.1393 −0.0236 1.0096 0.9579 1 1 WCM78_Z1_1 1163766819 66481851 0.2482 0.5388 1.9545 0.951 2 1 WCM78_Z1_1 11 6648281467399334 0.6682 1.088 NA NA NA NA WCM78_Z1_1 11 67399798 69063384 0.26320.5593 NA NA NA NA WCM78_Z1_1 11 69063594 75152243 −0.1596 −0.05520.9955 0.9294 1 1 WCM78_Z1_1 11 75152805 88924375 0.3157 0.6306 2.0951.0015 2 1 WCM78_Z1_1 11 88925201 116629800 −0.1465 −0.0348 1.017 0.93531 1 WCM78_Z1_1 11 116631510 119340576 0.3018 0.6118 1.9457 1.1107 2 1WCM78_Z1_1 11 119369420 134856556 −0.1131 0.0168 1.0489 0.9745 1 1WCM78_Z1_1 12 148639 14019098 0.4356 0.7899 2.4024 1.0556 2 1 WCM78_Z1_112 14576917 19671645 0.9662 1.4526 4.0866 1.3876 4 1 WCM78_Z1_1 1220522359 34182559 0.4111 0.7578 2.2527 1.1291 2 1 WCM78_Z1_1 12 3871069757106677 −0.0103 0.1714 1.1627 1.0895 1 1 WCM78_Z1_1 12 5710697260173262 0.419 0.7682 2.0954 1.3109 2 1 WCM78_Z1_1 12 62104181 69646914−8.00E−04 0.1855 1.226 1.0484 1 1 WCM78_Z1_1 12 69650492 77216256 0.37180.7057 2.1103 1.1515 2 1 WCM78_Z1_1 12 77222173 93175790 −0.0124 0.16831.1985 1.0489 1 1 WCM78_Z1_1 12 93181739 95771114 0.3807 0.7176 NA NA NANA WCM78_Z1_1 12 95774646 115801955 −0.005 0.1792 1.1573 1.1072 1 1WCM78_Z1_1 12 116399156 121341672 0.7824 1.2296 3.1784 1.5117 3 2WCM78_Z1_1 12 121416650 122265949 0.3894 0.7291 2.8742 0.441 3 0WCM78_Z1_1 12 122268091 133810703 −0.3537 −0.3704 1.0229 0.5243 1 1WCM78_Z1_1 13 19600371 30003017 −0.1011 0.0351 1.0621 0.9871 1 1WCM78_Z1_1 13 30014128 33316780 0.1833 0.4492 1.569 1.1616 2 1WCM78_Z1_1 13 33327642 44456410 −0.1313 −0.0113 1.0427 0.9417 1 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WCM78_Z1_1 16 67604 836829 −0.1665 −0.0659 1.01210.8986 1 1 WCM78_Z1_1 16 837073 2880797 0.2446 0.534 1.9326 0.9632 2 1WCM78_Z1_1 16 2881928 8722958 −0.1754 −0.0799 0.964 0.9283 1 1WCM78_Z1_1 16 8729124 11991733 0.1245 0.3665 1.3477 1.2307 1 1WCM78_Z1_1 16 12008872 33965562 −0.1432 −0.0297 1.0055 0.9538 1 1WCM78_Z1_1 16 34257013 48296699 0.1829 0.4485 NA NA NA NA WCM78_Z1_1 1648304001 48596287 0.0024 0.1901 NA NA NA NA WCM78_Z1_1 16 4864372054509664 −0.3651 −0.3899 1.1316 0.3948 1 0 WCM78_Z1_1 16 5469122384922841 −0.0325 0.1385 1.1319 1.0696 1 1 WCM78_Z1_1 16 8494022485392987 0.0388 0.2434 NA NA NA NA WCM78_Z1_1 16 85646998 888704600.3205 0.637 1.8775 1.2327 2 1 WCM78_Z1_1 16 88871202 90233626 0.03720.241 1.2713 1.0924 1 1 WCM78_Z1_1 17 131595 3794004 −0.1293 −0.00821.0541 0.9346 1 1 WCM78_Z1_1 17 3801316 4012978 −0.7687 −1.1663 0.88250.0087 1 0 WCM78_Z1_1 17 4015997 6703366 −0.1452 −0.0328 0.9927 0.9624 11 WCM78_Z1_1 17 6704132 8065671 −0.7254 −1.0722 0.9968 −0.0456 1 0WCM78_Z1_1 17 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51547037−0.155 −0.0479 1.1149 0.8198 1 1 WCM78_Z1_1 6 51586814 65622528 0.1090.3444 1.5662 0.9731 2 1 WCM78_Z1_1 6 65655779 107040160 −0.131 −0.01071.0462 0.939 1 1 WCM78_Z1_1 6 107050770 119623239 0.2427 0.5313 1.8341.0564 2 1 WCM78_Z1_1 6 119628098 128294933 −0.1456 −0.0334 1.04230.9119 1 1 WCM78_Z1_1 6 128297866 130762903 0.4837 0.8527 NA NA NA NAWCM78_Z1_1 6 131148737 137815297 −0.1412 −0.0266 1.0015 0.962 1 1WCM78_Z1_1 6 138192536 147704045 0.1013 0.3335 1.4345 1.0856 1 1WCM78_Z1_1 6 147830073 166952263 −0.1378 −0.0213 1.0021 0.9686 1 1WCM78_Z1_1 6 167040508 170893409 −0.679 −0.975 0.9842 0.0333 1 0WCM78_Z1_1 7 193451 3188637 0.5618 0.9533 2.8123 1.0602 3 1 WCM78_Z1_1 73197867 30029844 0.2568 0.5506 1.9494 0.9799 2 1 WCM78_Z1_1 7 3005447533384197 0.8429 1.3038 NA NA NA NA WCM78_Z1_1 7 33385839 49815105 0.06480.2811 1.4817 0.9486 1 1 WCM78_Z1_1 7 49815390 65439658 −0.1703 −0.07191.0005 0.9022 1 1 WCM78_Z1_1 7 65440053 79833065 0.1841 0.4503 1.77580.9568 2 1 WCM78_Z1_1 7 79840350 94043586 −0.1707 −0.0725 1.0225 0.87951 1 WCM78_Z1_1 7 94044543 100839424 0.0296 0.23 1.4142 0.9316 1 1WCM78_Z1_1 7 100839496 103848322 0.2322 0.5169 1.7479 1.1138 2 1WCM78_Z1_1 7 103969576 123143356 −0.065 0.0897 1.194 0.9344 1 1WCM78_Z1_1 7 123152035 135421928 0.2466 0.5366 1.8166 1.0846 2 1WCM78_Z1_1 7 135433327 147092792 −0.1455 −0.0333 0.9878 0.9666 1 1WCM78_Z1_1 7 147183104 148724945 0.4585 0.8199 NA NA NA NA WCM78_Z1_1 7148725458 150028027 0.7052 1.1342 2.3316 2.0582 2 2 WCM78_Z1_1 7150034173 151970797 0.4513 0.8105 2.6409 0.8667 3 1 WCM78_Z1_1 7152007133 158937066 −0.6469 −0.9099 1.0879 −0.0235 1 0 WCM78_Z1_1 8190908 4277512 −0.1567 −0.0506 0.9986 0.9324 1 1 WCM78_Z1_1 8 44949968749985 0.3125 0.6262 1.8954 1.1917 2 1 WCM78_Z1_1 8 8750407 54155419−0.1174 0.0102 1.038 0.9762 1 1 WCM78_Z1_1 8 54163541 69017590 0.07420.2946 1.373 1.08 1 1 WCM78_Z1_1 8 69018574 76476328 0.397 0.7392 2.14831.1901 2 1 WCM78_Z1_1 8 77616345 100654723 0.0924 0.3208 1.3062 1.1918 11 WCM78_Z1_1 8 100711890 103663925 0.8344 1.2934 NA NA NA NA WCM78_Z1_18 103664206 122626403 0.0972 0.3275 1.4468 1.063 1 1 WCM78_Z1_1 8122626551 132998459 0.4564 0.8172 2.5464 0.9775 3 1 WCM78_Z1_1 8132999908 134225367 0.7034 1.1319 NA NA NA NA WCM78_Z1_1 8 134232996136657349 1.7178 2.3151 NA NA NA NA WCM78_Z1_1 8 139144868 1443779830.7408 1.1784 3.6501 0.8764 4 1 WCM78_Z1_1 8 144378283 145806310 0.97621.4645 3.9272 1.5921 4 2 WCM78_Z1_1 8 145806491 146279472 0.7062 1.13543.4414 0.9523 3 1 WCM78_Z1_1 9 17060 2039814 −0.1805 −0.0878 1.06520.8167 1 1 WCM78_Z1_1 9 2047452 5535038 0.2434 0.5322 NA NA NA NAWCM78_Z1_1 9 5549588 12709175 −0.1079 0.0246 NA NA NA NA WCM78_Z1_1 912775909 16253063 0.2996 0.6088 NA NA NA NA WCM78_Z1_1 9 1641933432784197 −0.1317 −0.0119 1.0163 0.9673 1 1 WCM78_Z1_1 9 3278464035107517 0.2383 0.5253 1.8446 1.0338 2 1 WCM78_Z1_1 9 35107765 36276966−0.0884 0.0544 1.0526 1.0242 1 1 WCM78_Z1_1 9 36339787 38622116 0.25410.5469 NA NA NA NA WCM78_Z1_1 9 39078450 77277434 −0.1594 −0.0549 1.01520.9101 1 1 WCM78_Z1_1 9 77280458 86281347 0.154 0.4081 1.4706 1.1833 1 1WCM78_Z1_1 9 86292711 100698451 −0.1462 −0.0343 1.0144 0.9386 1 1WCM78_Z1_1 9 100700351 104433034 0.2026 0.476 1.5259 1.2558 2 1WCM78_Z1_1 9 104433235 141111414 −0.153 −0.0449 0.9829 0.9558 1 1WCM78_Z1_1 X 2707724 11130205 −0.1616 −0.0582 NA NA NA NA WCM78_Z1_1 X11136454 27999373 0.7075 1.1371 NA NA NA NA WCM78_Z1_1 X 2880751541206927 −0.2364 −0.1767 NA NA NA NA WCM78_Z1_1 X 41307160 484359080.4223 0.7724 NA NA NA NA WCM78_Z1_1 X 48542706 65486378 0.0827 0.3068NA NA NA NA WCM78_Z1_1 X 65819524 67944205 1.6731 2.2654 NA NA NA NAWCM78_Z1_1 X 68049652 127186187 −0.2133 −0.1397 NA NA NA NA WCM78_Z1_1 X128582347 134305059 0.1188 0.3584 NA NA NA NA WCM78_Z1_1 X 134655007154509348 −0.1786 −0.0849 NA NA NA NA WCM7_Tissue 1 14716 16254698−0.6288 −0.9144 1.049 0.0121 1 0 WCM7_Tissue 1 16255132 17087465 −0.5107−0.7372 0.8786 0.3212 1 0 WCM7_Tissue 1 17248521 37967613 −0.646 −0.94081.0614 −0.0195 1 0 WCM7_Tissue 1 37975029 39318120 −0.0412 −0.09061.0759 0.8024 1 1 WCM7_Tissue 1 39321475 144679970 −0.5849 −0.84761.0969 0.0145 1 0 WCM7_Tissue 1 144811819 249212558 0.0546 0.0327 1.12340.9224 1 1 WCM7_Tissue 10 226016 39006437 −0.0017 −0.0394 0.9956 0.95041 1 WCM7_Tissue 10 39011230 44866798 −0.5584 −0.808 NA NA NA NAWCM7_Tissue 10 44868828 54531331 0.0427 0.0176 1.2388 0.7858 1 1WCM7_Tissue 10 55566646 96602719 −0.6222 −0.9044 1.0494 0.0192 1 0WCM7_Tissue 10 96609769 135477937 0.0793 0.0642 1.0946 0.9964 1 1WCM7_Tissue 11 193096 134257494 0.0516 0.029 1.1453 0.8953 1 1WCM7_Tissue 12 247582 109042588 0.0636 0.0442 1.0469 1.0154 1 1WCM7_Tissue 12 109046120 123201311 −0.1332 −0.2114 0.882 0.8454 1 1WCM7_Tissue 12 123213956 133779351  3.00E−04 −0.0369 0.9999 0.9496 1 1WCM7_Tissue 13 19240930 115089411 −0.6332 −0.9212 1.0514 0.0047 1 0WCM7_Tissue 14 19377775 107283088 0.0603 0.04 1.0713 0.9849 1 1WCM7_Tissue 15 20169986 22709666 −0.2867 −0.4188 1.0808 0.4153 1 0WCM7_Tissue 15 22782337 102516473 −0.6345 −0.9231 1.0495 0.0053 1 0WCM7_Tissue 16 64456 50136324 −0.0246 −0.069 1.062 0.8446 1 1WCM7_Tissue 16 50245309 90162517 −0.6791 −0.9922 1.0285 −0.0231 1 0WCM7_Tissue 17 131595 81188087 0.0285 −7.00E−04 1.0969 0.9021 1 1WCM7_Tissue 18 47725 24056669 0.0552 0.0336 1.1489 0.8982 1 1WCM7_Tissue 18 24081044 74154807 −0.6652 −0.9706 1.0214 −8.00E−04  1 0WCM7_Tissue 18 74536282 78005194 0.0572 0.036 1.0841 0.9665 1 1WCM7_Tissue 19 110724 2901016 −0.0152 −0.0569 1.1006 0.8221 1 1WCM7_Tissue 19 2915494 19627096 −0.1373 −0.2169 0.8958 0.825 1 1WCM7_Tissue 19 19637074 59082684 −0.0366 −0.0847 1.0373 0.8486 1 1WCM7_Tissue 2 41609 66795846 0.0845 0.0707 2.1214 −0.0209 2 0WCM7_Tissue 2 66796154 69769730 0.5967 0.6943 NA NA NA NA WCM7_Tissue 269771644 176856991 0.082 0.0676 2.1041 −0.0081 2 0 WCM7_Tissue 2176860268 179621460 0.3921 0.4509 NA NA NA NA WCM7_Tissue 2 179622318243037091 0.078 0.0626 2.0988 −0.0101 2 0 WCM7_Tissue 20 68415 629589090.0011 −0.0359 1.0245 0.9264 1 1 WCM7_Tissue 21 9590334 48084177 0.05120.0284 1.0407 0.999 1 1 WCM7_Tissue 22 16255891 51216417 −0.6664 −0.97241.0195 −2.00E−04  1 0 WCM7_Tissue 3 361470 132051063 0.0709 0.05341.0589 1.0166 1 1 WCM7_Tissue 3 132056349 197847562 0.4994 0.5794 1.95261.036 2 1 WCM7_Tissue 4 53403 40440902 −0.6109 −0.887 1.0714 0.01 1 0WCM7_Tissue 4 40752866 164466928 0.0418 0.0164 1.027 0.9959 1 1WCM7_Tissue 4 164507052 177650817 −0.5864 −0.8499 1.1406 −0.031 1 0WCM7_Tissue 4 177713345 190947521 0.0935 0.0822 1.0841 1.0332 1 1WCM7_Tissue 5 140532 52398000 0.5392 0.6266 1.9968 1.0911 2 1WCM7_Tissue 5 52402932 132073106 0.0952 0.0843 2.1367 −0.0163 2 0WCM7_Tissue 5 132084132 180687821 0.5096 0.5915 1.9415 1.0721 2 1WCM7_Tissue 6 292536 64423298 0.0927 0.0812 1.1637 0.952 1 1 WCM7_Tissue6 66044947 170892772 −0.648 −0.9439 1.0322 0.0074 1 0 WCM7_Tissue 7195638 158935160 0.4968 0.5763 1.9183 1.0637 2 1 WCM7_Tissue 8 16353636644900 −0.6564 −0.9569 1.0629 −0.0325 1 0 WCM7_Tissue 8 3666153848114334 −0.0072 −0.0466 1.0395 0.897 1 1 WCM7_Tissue 8 48508535128972936 0.5001 0.5802 1.9678 1.0224 2 1 WCM7_Tissue 8 129021111146279513 0.0921 0.0804 1.1913 0.9234 1 1 WCM7_Tissue 9 14885 154472800.0195 −0.0122 1.0094 0.9737 1 1 WCM7_Tissue 9 15453096 28888864 −0.7082−1.0378 1.0232 −0.049 1 0 WCM7_Tissue 9 29999669 141071668 0.0579 0.0371.1385 0.9135 1 1 WCM7_Tissue X 2700146 154493585 −0.0194 −0.0624 NA NANA NA WCM80 1 14907 9995562 0.0513 0.0268 1.0245 1.013 1 1 WCM80 19996718 11189787 −0.4499 −1.1218 0.9119 0.0072 1 0 WCM80 1 11190646226175904 0.0436 0.0124 1.0087 1.0087 1 1 WCM80 1 226176043 227954677−0.4296 −1.0632 0.9346 0.0225 1 0 WCM80 1 227958225 249214018 0.0410.0076 1.0053 1.0053 1 1 WCM80 10 225938 135439027 0.0273 −0.0184 0.98730.9873 1 1 WCM80 11 193096 33881135 0.0865 0.0919 1.0658 1.0658 1 1WCM80 11 33886338 48347429 −0.4206 −1.0374 0.8087 0.1657 1 0 WCM80 1148366958 124135655 0.0336 −0.0065 0.9955 0.9955 1 1 WCM80 11 124179835125366605 −0.3855 −0.9405 1.0602 −0.0182 1 0 WCM80 11 125442373134605906 0.0379 0.0017 1.0012 1.0012 1 1 WCM80 12 148388 1041602930.0258 −0.0213 0.9854 0.9854 1 1 WCM80 12 104167656 108418514 −0.4349−1.0782 0.8505 0.0968 1 0 WCM80 12 108589691 110945998 0.0316 −0.01030.9929 0.9929 1 1 WCM80 12 110950705 112159518 −0.4313 −1.0678 NA NA NANA WCM80 12 112165777 124172706  9.00E−04 −0.0688 0.9534 0.9534 1 1WCM80 12 124175056 125591689 −0.461 −1.1545 0.9235 −0.0251 1 0 WCM80 12125591849 133810703 0.0656 0.0535 1.0378 1.0378 1 1 WCM80 13 1904199433020568 −0.0058 −0.0819 0.9448 0.9448 1 1 WCM80 13 33054686 76111751−0.4875 −1.2349 0.8315 0.0183 1 0 WCM80 13 76124003 115089411 −0.0217−0.1128 0.9339 0.9158 1 1 WCM80 14 19110297 107283263 0.0262 −0.02040.9859 0.9859 1 1 WCM80 15 20083928 27017924 0.4217 0.6569 2.1112 1.04212 1 WCM80 15 27018841 45879748 −0.4707 −1.1837 0.8888 −0.0083 1 0 WCM8015 45884450 102515248 0.0582 0.0398 1.0279 1.0279 1 1 WCM80 16 6690850106594 0.034 −0.0058 0.996 0.996 1 1 WCM80 16 50109478 66620997−0.4279 −1.0582 0.904 0.0564 1 0 WCM80 16 66621996 81744842 0.0192−0.0337 0.9769 0.9769 1 1 WCM80 16 81745317 90128849 −0.3805 −0.9271 0.80.2519 1 0 WCM80 16 90130039 90168857 0.0696 0.0609 NA NA NA NA WCM80 17131595 81187930 0.0369 −2.00E−04 0.9998 0.9998 1 1 WCM80 18 4768078005267 0.0122 −0.0471 0.9679 0.9679 1 1 WCM80 19 105021 590936960.0639 0.0504 1.0355 1.0355 1 1 WCM80 2 41658 211542575 0.0225 −0.02740.9812 0.9812 1 1 WCM80 2 212240652 217366164 −0.3564 −0.8633 0.98640.113 1 0 WCM80 2 217443557 243037103 0.0355 −0.0028 0.998 0.998 1 1WCM80 20 68299 62934572 0.0452 0.0154 1.0107 1.0107 1 1 WCM80 21 959030548084189 0.006 −0.0591 0.9654 0.9543 1 1 WCM80 22 16159016 175283940.5175 0.8037 NA NA NA NA WCM80 22 17577957 20290883 −0.4152 −1.02240.9777 0.0069 1 0 WCM80 22 20291208 51223730 0.0592 0.0415 1.0292 1.02921 1 WCM80 3 239390 197896724 0.0306 −0.0122 0.9916 0.9916 1 1 WCM80 453377 174253209 0.0132 −0.0453 0.9691 0.9691 1 1 WCM80 4 174254091190904482 −0.5256 −1.3559 0.8378 −0.0564 1 0 WCM80 5 90647 1806878040.0264 −0.02 0.9862 0.9862 1 1 WCM80 6 203397 170892848 0.0153 −0.04120.9719 0.9719 1 1 WCM80 7 193265 158937161 0.0203 −0.0316 0.9783 0.97831 1 WCM80 8 163457 2092641 −0.4777 −1.2047 0.9529 −0.0852 1 0 WCM80 82092921 3919229 0.4394 0.6843 1.9187 1.2952 2 1 WCM80 8 4255373 42911666−0.4847 −1.2261 0.848 0.0069 1 0 WCM80 8 42914223 146279434 0.379 0.58951.8324 1.1771 2 1 WCM80 9 14880 3012996 0.0024 −0.0661 1.8947 0.0158 2 0WCM80 9 3014100 4703077 −0.9891 −4.6541 0.1166 −0.0372 0 0 WCM80 94706214 8507472 0.0289 −0.0152 2.0102 −0.0312 2 0 WCM80 9 8517899141107533 0.03 −0.0132 0.9909 0.9909 1 1 WCM80 X 2700110 154493609−0.0598 −0.1884 NA NA NA NA WCM80_Z1_1 1 69590 9932071 0.0291 0.02181.0489 0.9816 1 1 WCM80_Z1_1 1 9990413 11204736 −0.5711 −0.9523 1.02210.0115 1 0 WCM80_Z1_1 1 11205053 226128842 0.0138 −3.00E−04 1.01140.9882 1 1 WCM80_Z1_1 1 226173146 227968259 −0.6038 −1.0141 0.991−7.00E−04  1 0 WCM80_Z1_1 1 228003508 249212366 0.0031 −0.0158 1.0020.9761 1 1 WCM80_Z1_1 10 225981 135440105 0.0163 0.0034 1.0125 0.9922 11 WCM80_Z1_1 11 193124 33902990 0.0118 −0.0032 1.0152 0.9804 1 1WCM80_Z1_1 11 34073997 48328644 −0.5589 −0.9296 1.0317 0.0184 1 0WCM80_Z1_1 11 48346822 124135662 0.0091 −0.0071 1.0081 0.9821 1 1WCM80_Z1_1 11 124179835 125366466 −0.539 −0.8929 1.0937 −0.0166 1 0WCM80_Z1_1 11 125366680 134856536 0.0117 −0.0034 1.0309 0.9644 1 1WCM80_Z1_1 12 148642 104151962 0.0093 −0.0067 1.0517 0.939 1 1WCM80_Z1_1 12 104153004 104492158 −0.5435 −0.9012 NA NA NA NA WCM80_Z1_112 104495751 105467741 −0.0386 −0.0768 NA NA NA NA WCM80_Z1_1 12105501594 108589662 −0.5318 −0.8797 1.0111 0.0759 1 0 WCM80_Z1_1 12108589886 110956484 0.0189 0.007 1.0296 0.9802 1 1 WCM80_Z1_1 12110957663 112035573 −0.571 −0.952 NA NA NA NA WCM80_Z1_1 12 112036794113624746 0.0179 0.0056 1.0984 0.9095 1 1 WCM80_Z1_1 12 113629230114841579 −0.5818 −0.9723 NA NA NA NA WCM80_Z1_1 12 115109666 1242093320.0094 −0.0067 1.0532 0.9376 1 1 WCM80_Z1_1 12 124210786 125619355−0.5642 −0.9394 1.068 −0.0251 1 0 WCM80_Z1_1 12 125621409 1338107030.0127 −0.0018 1.0161 0.9814 1 1 WCM80_Z1_1 13 19600371 33091980 0.01830.0062 1.0319 0.9767 1 1 WCM80_Z1_1 13 33095529 76055820 −0.5996 −1.0060.9791 0.0167 1 0 WCM80_Z1_1 13 76101983 115089411 −0.0015 −0.02241.0046 0.9645 1 1 WCM80_Z1_1 14 19377733 107283210 0.0109 −0.0045 1.00410.9897 1 1 WCM80_Z1_1 15 20170057 27018858 0.4307 0.5708 2.0657 0.905 21 WCM80_Z1_1 15 27114425 45059946 −0.5745 −0.9586 1.0437 −0.0146 1 0WCM80_Z1_1 15 45249116 45492969 −1.6963 NA NA NA NA NA WCM80_Z1_1 1545544449 45782955 −0.6003 −1.0074 NA NA NA NA WCM80_Z1_1 15 45803456102517641 0.0058 −0.012 1.0062 0.9773 1 1 WCM80_Z1_1 16 67604 498565920.0274 0.0193 1.0252 1.0018 1 1 WCM80_Z1_1 16 50059580 66647013 −0.5861−0.9805 1.0327 −0.019 1 0 WCM80_Z1_1 16 66651247 81743404 0.0183 0.00631.0276 0.9811 1 1 WCM80_Z1_1 16 81816733 90162178 −0.5679 −0.9464 0.81710.2207 1 0 WCM80_Z1_1 17 131595 81083567 0.0146  9.00E−04 1.0383 0.963 11 WCM80_Z1_1 18 48206 78005215 0.0557 0.0601 1.0724 1.0127 1 1WCM80_Z1_1 19 281422 59083985 0.0146  8.00E−04 1.0513 0.9498 1 1WCM80_Z1_1 2 41609 215878343 0.0055 −0.0123 1.003 0.98 1 1 WCM80_Z1_1 2215880324 217366061 −0.5923 −0.9921 NA NA NA NA WCM80_Z1_1 2 217498633242946607 0.0207 0.0097 1.0257 0.9878 1 1 WCM80_Z1_1 20 68406 629191180.0222 0.0119 1.02 0.9966 1 1 WCM80_Z1_1 21 9907291 48084204 −0.0088−0.0332 0.9958 0.9587 1 1 WCM80_Z1_1 22 16287449 17488945 0.3694 0.4904NA NA NA NA WCM80_Z1_1 22 17566091 20255183 −0.5528 −0.9182 1.01740.0409 1 0 WCM80_Z1_1 22 20302698 51215137 0.0279 0.0201 1.0711 0.957 11 WCM80_Z1_1 3 239350 197894712 0.0068 −0.0104 1.0029 0.9827 1 1WCM80_Z1_1 4 59390 174312482 −4.00E−04 −0.0209 0.9986 0.9727 1 1WCM80_Z1_1 4 174448142 190873327 −0.6063 −1.0188 0.9658 0.0212 1 0WCM80_Z1_1 5 140532 180687808 0.0055 −0.0123 1.0059 0.9771 1 1WCM80_Z1_1 6 203695 170893450 0.0014 −0.0183 0.9989 0.9759 1 1WCM80_Z1_1 7 193451 158937375 0.0121 −0.0028 1.0096 0.9865 1 1WCM80_Z1_1 8 190907 2092866 −0.6092 −1.0243 NA NA NA NA WCM80_Z1_1 82796235 3889551 0.3922 0.5205 NA NA NA NA WCM80_Z1_1 8 4277559 42873514−0.5705 −0.9512 1.0333 0.0011 1 0 WCM80_Z1_1 8 42911680 87242373 0.41930.5559 1.9806 0.9595 2 1 WCM80_Z1_1 8 87386317 90802584 −7.00E−04−0.0214 NA NA NA NA WCM80_Z1_1 8 90921923 146279480 0.4222 0.5598 1.96830.9797 2 1 WCM80_Z1_1 9 17110 2838500 −0.0278 −0.061 1.9511 −0.034 2 0WCM80_Z1_1 9 3225187 4544670 −1.675 −12.1435 NA NA NA NA WCM80_Z1_1 94561454 4646492 0.0543 0.0581 NA NA NA NA WCM80_Z1_1 9 4656051 4701874−1.3652 −3.2124 NA NA NA NA WCM80_Z1_1 9 4706022 8525041 −0.0147 −0.0418NA NA NA NA WCM80_Z1_1 9 8526630 141111414 0.0139 −1.00E−04 1.00570.9941 1 1 WCM80_Z1_1 X 2700119 154509348 −0.0264 −0.0589 NA NA NA NAWCM89 1 14930 249214028 0.0328 NA NA NA NA NA WCM89 10 226021 1354779130.0274 NA NA NA NA NA WCM89 11 193096 134605916 0.0252 NA NA NA NA NAWCM89 12 148480 133810703 0.0102 NA NA NA NA NA WCM89 13 19041994115089411 0.0198 NA NA NA NA NA WCM89 14 19110178 107283266 0.0235 NA NANA NA NA WCM89 15 20083896 102506257 0.0403 NA NA NA NA NA WCM89 1666905 90168857 0.0216 NA NA NA NA NA WCM89 17 131595 81187845 0.0256 NANA NA NA NA WCM89 18 47738 78005205 0.0162 NA NA NA NA NA WCM89 19105080 59093696 0.0042 NA NA NA NA NA WCM89 2 41602 243037022 0.0216 NANA NA NA NA WCM89 20 68346 270236 0.0386 NA NA NA NA NA WCM89 20 271168278806 −1.4078 NA NA NA NA NA WCM89 20 278983 62934617 0.0425 NA NA NANA NA WCM89 21 9590314 48084204 0.0192 NA NA NA NA NA WCM89 22 1615906051223730 0.0617 NA NA NA NA NA WCM89 3 239531 197896705 0.0309 NA NA NANA NA WCM89 4 53345 190878479 0.0148 NA NA NA NA NA WCM89 5 90684180687847 0.0158 NA NA NA NA NA WCM89 6 203369 170892854 0.0112 NA NA NANA NA WCM89 7 193254 158937161 0.0078 NA NA NA NA NA WCM89 8 163438146279489 0.0106 NA NA NA NA NA WCM89 9 14893 141107582 0.0332 NA NA NANA NA WCM89 X 2700166 154493598 −0.1228 NA NA NA NA NA WCM89_X1_1 169590 38005914 −0.0279 −0.2393 0.9142 0.7802 1 1 WCM89_X1_1 1 3800625638463196 −0.699 −1.5195 0.6559 0.0417 1 0 WCM89_X1_1 1 38463504 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WCM89_X1_1 12 93897959 123694661 −0.0864 −0.3331.1052 0.4826 1 0 WCM89_X1_1 12 123699304 133810703 −0.3162 −0.72621.2035 0.0055 1 0 WCM89_X1_1 13 19600515 115089411 −0.3999 −0.88190.6193 0.4661 1 0 WCM89_X1_1 14 19377692 107283184 0.1228 −0.0077 0.99910.9902 1 1 WCM89_X1_1 15 20170123 102506284 0.1239 −0.0062 1.0062 0.98531 1 WCM89_X1_1 16 67604 33020784 0.3636 0.3389 1.5055 1.024 2 1WCM89_X1_1 16 33500782 90162133 −0.1072 −0.3668 1.0265 0.5244 1 1WCM89_X1_1 17 131595 20483882 −0.4152 −0.9114 1.0387 0.0247 1 0WCM89_X1_1 17 20798992 81083455 0.1509 0.034 1.0314 1.0162 1 1WCM89_X1_1 18 49007 7034508 −0.0951 −0.3472 0.9817 0.5905 1 1 WCM89_X1_118 7036028 13387727 0.2845 0.2278 1.878 0.464 2 0 WCM89_X1_1 18 1343827419751474 −0.5299 −1.1411 NA NA NA NA WCM89_X1_1 18 19752089 286480630.2611 0.1945 1.8678 0.4208 2 0 WCM89_X1_1 18 28648310 78005210 −0.1696−0.4704 0.9076 0.536 1 1 WCM89_X1_1 19 281435 59083951 0.1124 −0.02330.9869 0.981 1 1 WCM89_X1_1 2 41613 286163 −0.0245 −0.234 NA NA NA 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WCM89_X1_1 5 140559 1806877760.0384 −0.1359 0.9213 0.8989 1 1 WCM89_X1_1 6 203552 7727404 −0.6648−1.4384 0.5663 0.1717 1 0 WCM89_X1_1 6 7727750 170893438 −0.1689 −0.46910.9702 0.4745 1 0 WCM89_X1_1 7 193222 39649510 0.0603 −0.1023 0.95010.913 1 1 WCM89_X1_1 7 39726338 158937416 −0.1982 −0.5187 0.9527 0.44321 0 WCM89_X1_1 8 190897 17924739 −0.2095 −0.5381 0.9674 0.4099 1 0WCM89_X1_1 8 17927304 28420497 −0.9267 −2.1459 0.476 −0.0241 0 0WCM89_X1_1 8 28573703 48874714 −0.2359 −0.5837 0.9155 0.4191 1 0WCM89_X1_1 8 48874963 66619386 0.367 0.3436 1.3535 1.1844 1 1 WCM89_X1_18 66620187 86027716 0.8716 1.0047 3.1161 0.8969 3 1 WCM89_X1_1 886035738 92407324 0.4433 0.4485 1.7584 0.9709 2 1 WCM89_X1_1 8 92972719114627743 −0.1154 −0.3802 1.0709 0.4657 1 0 WCM89_X1_1 8 116426335143602208 0.2541 0.1844 1.4328 0.8399 1 1 WCM89_X1_1 8 143603425146279423 −0.345 −0.7789 0.814 0.3516 1 0 WCM89_X1_1 9 17066 19378494−0.4428 −0.9648 1.0288 −0.0042 1 0 WCM89_X1_1 9 19378751 71152348 0.1131−0.0223 1.0039 0.9655 1 1 WCM89_X1_1 9 71155503 86414206 −0.5354 −1.15250.8588 0.0408 1 0 WCM89_X1_1 9 86421335 141111414 0.0343 −0.1422 0.91170.9005 1 1 WCM89_X1_1 X 2707716 19027799 0.0057 −0.1865 NA NA NA NAWCM89_X1_1 X 19032163 48791818 −0.4677 −1.0143 NA NA NA NA WCM89_X1_1 X48792099 63410086 0.1762 0.0713 NA NA NA NA WCM89_X1_1 X 6341055569282985 1.7947 2.0862 NA NA NA NA WCM89_X1_1 X 69353804 1545093480.1597 0.0471 NA NA NA NA WCM89_Z1_1 1 69594 917492 0.0777 0.2591 NA NANA NA WCM89_Z1_1 1 935081 37980309 −0.0466 −0.0455 1.0804 0.8575 1 1WCM89_Z1_1 1 38003554 38463504 −0.405 −1.2804 0.9491 −0.1257 1 0WCM89_Z1_1 1 38463706 85136473 −0.0251 0.01 1.0429 0.971 1 1 WCM89_Z1_11 85136884 249212366 0.1218 0.359 1.3167 1.2484 1 1 WCM89_Z1_1 10 22597985901313 0.0503 0.1952 1.1558 1.1341 1 1 WCM89_Z1_1 10 85902478111629778 −0.3054 −0.8546 1.1056 4.00E−04 1 0 WCM89_Z1_1 10 111630651135440105 0.0194 0.121 1.1114 1.0636 1 1 WCM89_Z1_1 11 193112 1348565590.047 0.1874 1.1549 1.1225 1 1 WCM89_Z1_1 12 148644 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WCM89_Z1_1 2 8822985 105941610.213 0.5541 NA NA NA NA WCM89_Z1_1 2 10595578 60688446 −0.1788 −0.42050.8003 0.694 1 1 WCM89_Z1_1 2 60688928 62934335 0.1741 0.4725 2.48260.2925 2 0 WCM89_Z1_1 2 62998533 96942672 −0.1733 −0.4037 0.7954 0.71651 1 WCM89_Z1_1 2 96942929 96992374 0.0781 0.26 NA NA NA NA WCM89_Z1_1 296992814 152127328 −0.0145 0.0368 1.0673 0.9844 1 1 WCM89_Z1_1 2152128190 242946616 0.1089 0.3301 1.5279 0.9863 2 1 WCM89_Z1_1 20 6837362904845 −0.0364 −0.0192 0.997 0.9766 1 1 WCM89_Z1_1 21 9907301 398228030.0547 0.2057 1.2157 1.0907 1 1 WCM89_Z1_1 21 39947586 43133829 −0.2935−0.8099 0.9952 0.1457 1 0 WCM89_Z1_1 21 43134212 48084204 0.0491 0.19231.24 1.0451 1 1 WCM89_Z1_1 22 16287509 51215120 0.0429 0.1775 1.14171.1202 1 1 WCM89_Z1_1 3 239459 67054185 0.0543 0.2047 1.1524 1.1524 1 1WCM89_Z1_1 3 67054451 74548852 −0.323 −0.9232 1.0544 3.00E−04 1 0WCM89_Z1_1 3 75263631 197896714 0.0488 0.1917 1.1448 1.1394 1 1WCM89_Z1_1 4 59394 102712108 0.0063 0.0889 1.0688 1.0583 1 1 WCM89_Z1_14 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143695144 145171114 0.1001 0.3105 1.9832 0.497 2 0WCM89_Z1_1 8 145218743 146279489 −0.1492 −0.3308 NA NA NA NA WCM89_Z1_19 17055 19352622 −0.3083 −0.8658 1.1171 −0.0196 1 0 WCM89_Z1_1 919357090 71152177 0.066 0.2321 1.232 1.117 1 1 WCM89_Z1_1 9 7115554986322524 −0.3105 −0.8744 1.1467 −0.0557 1 0 WCM89_Z1_1 9 86327752141111414 0.0601 0.2182 1.1769 1.1497 1 1 WCM89_Z1_1 X 2707682 19663526−0.0076 0.0542 NA NA NA NA WCM89_Z1_1 X 19666174 48435411 −0.3597−1.0746 NA NA NA NA WCM89_Z1_1 X 48435890 62926275 0.0744 0.2516 NA NANA NA WCM89_Z1_1 X 63005022 65427997 0.5097 1.1115 NA NA NA NAWCM89_Z1_1 X 65474912 69282771 1.9692 3.1176 NA NA NA NA WCM89_Z1_1 X69353859 154509348 0.0749 0.2529 NA NA NA NA WCM89_Z12_1 1 69603249212402 −0.0649 −0.0022 1.0278 0.9693 1 1 WCM89_Z12_1 10 225988135440081 −0.0724 −0.0206 0.9979 0.9737 1 1 WCM89_Z12_1 11 193112134856592 −0.0666 −0.0064 1.0175 0.9737 1 1 WCM89_Z12_1 12 148811133810703 −0.0576 0.0155 1.0353 0.9863 1 1 WCM89_Z12_1 13 19600515115089411 −0.0729 −0.0219 1.0165 0.9534 1 1 WCM89_Z12_1 14 19377701107283210 −0.0696 −0.0137 1.1314 0.8496 1 1 WCM89_Z12_1 15 20170057102506273 −0.068 −0.0097 1.0273 0.9592 1 1 WCM89_Z12_1 16 67604 90233627−0.0628 0.0029 1.0264 0.9776 1 1 WCM89_Z12_1 17 131595 81083507 −0.0679−0.0095 1.0129 0.974 1 1 WCM89_Z12_1 18 49046 78005210 −0.0835 −0.04810.9865 0.948 1 1 WCM89_Z12_1 19 281499 59083923 −0.0409 0.0557 1.06411.0145 1 1 WCM89_Z12_1 2 41623 242946616 −0.0669 −0.0071 1.0073 0.9829 11 WCM89_Z12_1 20 68375 62904861 −0.0705 −0.0159 1.0133 0.9647 1 1WCM89_Z12_1 21 9907316 48084214 −0.0975 −0.0832 0.9869 0.9011 1 1WCM89_Z12_1 22 16287479 51215134 −0.0794 −0.0379 1.0006 0.9475 1 1WCM89_Z12_1 3 239431 197896714 −0.0752 −0.0275 0.9908 0.9714 1 1WCM89_Z12_1 4 59389 190426502 −0.0727 −0.0214 1.0022 0.9683 1 1WCM89_Z12_1 5 140515 180687768 −0.0515 0.0304 1.0434 0.9991 1 1WCM89_Z12_1 6 203615 170893454 −0.068 −0.0098 1.0224 0.9641 1 1WCM89_Z12_1 7 193205 158937400 −0.0643 −7.00E−04 1.019 0.98 1 1WCM89_Z12_1 8 190908 4851906 −0.0263 0.0902 NA NA NA NA WCM89_Z12_1 86266883 27650185 −0.361 −0.8724 1.0962 −0.0037 1 0 WCM89_Z12_1 827657086 146279511 −0.0708 −0.0167 1.0152 0.9618 1 1 WCM89_Z12_1 9 17058141111414 −0.059 0.0122 1.0403 0.9767 1 1 WCM89_Z12_1 X 2707700154509348 −0.0289 0.0841 NA NA NA NA WCM89_Z17_1 1 69610 249212348−0.0424 0.0679 1.1654 0.931 1 1 WCM89_Z17_1 10 225981 85909909 −0.02580.1079 1.1009 1.0545 1 1 WCM89_Z17_1 10 85910582 111639975 −0.3721−0.9222 1.0448 0.0106 1 0 WCM89_Z17_1 10 111640659 135440108 −0.1009−0.0786 1.0106 0.8834 1 1 WCM89_Z17_1 11 193112 294119 −0.1405 −0.18311.4141 0.3475 1 0 WCM89_Z17_1 11 294453 2683222 −0.3069 −0.6864 0.97780.265 1 0 WCM89_Z17_1 11 2790078 134856562 −0.0328 0.0912 1.0729 1.05761 1 WCM89_Z17_1 12 148675 16347371 −0.3313 −0.7714 1.1303 0.0415 1 0WCM89_Z17_1 12 16369897 123714910 −0.1291 −0.1526 1.0628 0.7365 1 1WCM89_Z17_1 12 123738311 133810703 −0.4298 −1.1577 0.9392 −0.0427 1 0WCM89_Z17_1 13 19600515 115089411 −0.1298 −0.1545 0.9392 0.8577 1 1WCM89_Z17_1 14 19377692 107283027 −0.1525 −0.2159 1.0404 0.6816 1 1WCM89_Z17_1 15 20170003 102506282 −0.0888 −0.0473 0.9998 0.9356 1 1WCM89_Z17_1 16 67604 815266 −0.1473 −0.2015 0.9858 0.7535 1 1WCM89_Z17_1 16 815560 49315259 −0.0794 −0.0236 1.0161 0.9515 1 1WCM89_Z17_1 16 49407998 90233627 −0.2291 −0.4365 1.0479 0.43 1 0WCM89_Z17_1 17 131595 20363675 −0.3606 −0.8786 1.0324 0.0554 1 0WCM89_Z17_1 17 20483308 80789885 −0.0907 −0.0523 0.9965 0.9324 1 1WCM89_Z17_1 17 80790093 81083455 −0.3406 −0.8049 NA NA NA NA WCM89_Z17_118 49005 78005214 −0.1723 −0.2707 1.0851 0.5727 1 1 WCM89_Z17_1 19281491 15166802 −0.1113 −0.1056 0.9683 0.8906 1 1 WCM89_Z17_1 1915198024 15198606 −1.9732 NA NA NA NA NA WCM89_Z17_1 19 1519875159083953 −0.043 0.0667 1.2154 0.8792 1 1 WCM89_Z17_1 2 41614 127447856−0.0695 0.0013 1.0234 0.9784 1 1 WCM89_Z17_1 2 127451505 2253466460.1149 0.4243 1.5948 1.089 2 1 WCM89_Z17_1 2 225360672 242946616 −0.0887−0.0473 1.0171 0.9184 1 1 WCM89_Z17_1 20 68406 62904881 −0.0829 −0.03230.9952 0.9605 1 1 WCM89_Z17_1 21 9907297 48084226 −0.16 −0.2366 1.01790.6797 1 1 WCM89_Z17_1 22 16287467 51215120 −0.1505 −0.2105 0.8855 0.8431 1 WCM89_Z17_1 3 239350 197896711 −0.0232 0.1144 1.0877 1.0773 1 1WCM89_Z17_1 4 59375 190426502 −0.0763 −0.0157 1.0215 0.9568 1 1WCM89_Z17_1 5 140559 180687773 −0.0555 0.0359 1.0479 1.0025 1 1WCM89_Z17_1 6 203515 170893427 −0.1869 −0.3121 0.8331 0.7778 1 1WCM89_Z17_1 7 193451 158937375 −0.0611 0.0222 1.0381 0.9929 1 1WCM89_Z17_1 8 190906 17924729 0.0047 0.18 1.1355 1.1302 1 1 WCM89_Z17_18 17927313 29035028 −0.3258 −0.752 1.1843 0.0033 1 0 WCM89_Z17_1 829037644 146279489 −0.0209 0.1198 1.1151 1.0582 1 1 WCM89_Z17_1 9 1706619360389 −0.2928 −0.6386 1.0108 0.2738 1 0 WCM89_Z17_1 9 1936189836170952 −0.0322 0.0928 1.1537 0.9791 1 1 WCM89_Z17_1 9 3617120086243114 −0.2417 −0.475 1.1323 0.3067 1 0 WCM89_Z17_1 9 86243799126133804 −0.018 0.1267 1.1203 1.0633 1 1 WCM89_Z17_1 9 126134542141111414 −0.2806 −0.5986 0.8483 0.4724 1 0 WCM89_Z17_1 X 2707700154509348 0.0027 0.1754 NA NA NA NA WCM89_ZLN1_1 1 69592 249212366−0.0556 0.0555 1.0579 1.0205 1 1 WCM89_ZLN1_1 10 225960 85904745 −0.03530.1073 1.0772 1.0772 1 1 WCM89_ZLN1_1 10 85908571 111879244 −0.3211−0.7605 0.9636 0.217 1 0 WCM89_ZLN1_1 10 111881962 135440090 −0.181−0.2916 0.8586 0.7754 1 1 WCM89_ZLN1_1 11 193112 134856592 −0.05840.0485 1.0555 1.0129 1 1 WCM89_ZLN1_1 12 148674 14650619 −0.2948 −0.66361.0002 0.2625 1 0 WCM89_ZLN1_1 12 14650954 77440011 −0.143 −0.18051.1288 0.636 1 1 WCM89_ZLN1_1 12 77440093 94658921 0.1288 0.4891 1.58261.2245 2 1 WCM89_ZLN1_1 12 94671859 123787393 −0.1774 −0.281 0.85740.7887 1 1 WCM89_ZLN1_1 12 123789135 133810703 −0.394 −1.0562 0.94990.0119 1 0 WCM89_ZLN1_1 13 19600515 115089411 −0.1122 −0.0945 0.98030.893 1 1 WCM89_ZLN1_1 14 19377712 107283019 −0.0644 0.033 1.0444 1.00191 1 WCM89_ZLN1_1 15 20170019 102506284 −0.1184 −0.1116 0.9486 0.9026 1 1WCM89_ZLN1_1 16 67604 90233622 −0.1427 −0.1799 1.0739 0.6917 1 1WCM89_ZLN1_1 17 131595 21201719 −0.3258 −0.7782 1.0327 0.1335 1 0WCM89_ZLN1_1 17 21202237 80992927 −0.0663 0.028 1.0434 0.9957 1 1WCM89_ZLN1_1 17 81006348 81083455 −0.2889 −0.6428 NA NA NA NAWCM89_ZLN1_1 18 49021 78005226 −0.0428 0.0884 1.0632 1.0632 1 1WCM89_ZLN1_1 19 281430 59083951 −0.0873 −0.0272 1.1041 0.8585 1 1WCM89_ZLN1_1 2 41614 98429177 −0.0901 −0.0347 1.177 0.7754 1 1WCM89_ZLN1_1 2 98430495 235404927 0.0553 0.3251 1.2527 1.2527 1 1WCM89_ZLN1_1 2 235405215 242946616 −0.0603 0.0434 1.0811 0.98 1 1WCM89_ZLN1_1 20 68351 62904848 −0.0921 −0.0401 0.9882 0.957 1 1WCM89_ZLN1_1 21 9907291 48084207 −0.0938 −0.0445 1.2063 0.7329 1 1WCM89_ZLN1_1 22 16287488 51215157 −0.1085 −0.0843 0.9844 0.902 1 1WCM89_ZLN1_1 3 239398 197896720 −0.0145 0.1591 1.1358 1.0973 1 1WCM89_ZLN1_1 4 59361 190426502 −0.0483 0.0742 1.0528 1.0528 1 1WCM89_ZLN1_1 5 140448 180687804 −0.0333 0.1122 1.1107 1.051 1 1WCM89_ZLN1_1 6 203535 170893415 −0.1467 −0.1913 1.1115 0.6401 1 1WCM89_ZLN1_1 7 193451 158937416 −0.0849 −0.0208 1.0145 0.9569 1 1WCM89_ZLN1_1 8 190897 18257624 −0.1265 −0.134 0.952 0.8706 1 1WCM89_ZLN1_1 8 18257854 28409255 −0.5041 −1.6184 0.5077 0.1437 1 0WCM89_ZLN1_1 8 28413362 52258494 −0.2541 −0.5228 0.8078 0.5843 1 1WCM89_ZLN1_1 8 52284523 67509770 −0.047 0.0777 1.0768 1.0338 1 1WCM89_ZLN1_1 8 67511377 81471724 0.2396 0.7188 2.2391 1.0526 2 1WCM89_ZLN1_1 8 81471908 142498652 −0.0506 0.0685 1.0647 1.0325 1 1WCM89_ZLN1_1 8 142504986 146279507 −0.2726 −0.5857 0.9605 0.3722 1 0WCM89_ZLN1_1 9 17053 271651 0.086 0.3949 NA NA NA NA WCM89_ZLN1_1 9286593 18950895 −0.2877 −0.6386 1.1244 0.1603 1 0 WCM89_ZLN1_1 919032907 141111414 −0.1063 −0.0783 0.9755 0.9188 1 1 WCM89_ZLN1_1 X2707687 154509348 0.0051 0.2067 NA NA NA NA WCM9 1 14907 2492139640.0563 0.1877 1.1389 1.1389 1 1 WCM9 10 225960 135477937 0.0359 0.11211.0808 1.0808 1 1 WCM9 11 193065 62301149 0.0867 0.2953 1.2271 1.2271 11 WCM9 11 62301560 70332804 −0.067 −0.322 0.8 0.8 1 1 WCM9 11 70333178134605906 0.0508 0.1677 1.1233 1.1233 1 1 WCM9 12 148465 1338107030.0077 0.0029 1.002 1.002 1 1 WCM9 13 19041965 115089411 −0.0486 −0.23650.8488 0.8488 1 1 WCM9 14 19110239 107283269 0.006 −0.0039 0.9973 0.99731 1 WCM9 15 20083887 102515226 0.0612 0.2056 1.1531 1.1531 1 1 WCM9 1664430 90168680 −0.0152 −0.0909 0.9389 0.9389 1 1 WCM9 17 131595 811879250.0052 −0.0073 0.9949 0.9949 1 1 WCM9 18 47609 78005164 0.0021 −0.01970.9864 0.9864 1 1 WCM9 19 105021 8992978 −0.0859 −0.4139 0.7506 0.7506 11 WCM9 19 8993501 9204307 0.6002 1.6014 3.1792 2.8895 3 3 WCM9 199204568 43093154 −0.0361 −0.1807 0.8823 0.8823 1 1 WCM9 19 4309380743858051 0.6533 1.7051 3.4421 3.079 3 3 WCM9 19 43858556 59093696−0.0226 −0.1223 0.9187 0.9187 1 1 WCM9 2 41647 243037091 0.0192 0.04821.0339 1.0339 1 1 WCM9 20 68375 62959285 0.0329 0.1008 1.0724 1.0724 1 1WCM9 21 9590305 48084201 −0.0323 −0.1643 0.8924 0.8924 1 1 WCM9 2216159043 51223730 0.0577 0.1928 1.143 1.143 1 1 WCM9 3 239339 1978966560.0421 0.1356 1.0985 1.0985 1 1 WCM9 4 53446 190903980 −0.0039 −0.04410.9699 0.9699 1 1 WCM9 5 90537 140086191 −9.00E−04 −0.0318 0.9782 0.97821 1 WCM9 5 140166824 140812117 −0.4111 NA −0.0064 −0.0064 0 0 WCM9 5140812420 180687821 0.032 0.0976 1.07 1.07 1 1 WCM9 6 203546 170892877−0.0041 −0.0448 0.9694 0.9694 1 1 WCM9 7 193189 158937142 −0.0018−0.0357 0.9756 0.9756 1 1 WCM9 8 163527 146279384 −0.0111 −0.0739 0.950.95 1 1 WCM9 9 14822 141107545 0.0458 0.1494 1.1091 1.1091 1 1 WCM9 X2700148 154507335 0.0182 0.0443 NA NA NA NA WCM90 1 14907 1149078 0.01450.0662 1.0597 1.0343 1 1 WCM90 1 1149480 1458176 −0.1143 −0.366 0.87170.6802 1 1 WCM90 1 1458275 154744489 −0.0806 −0.2437 0.8446 0.8446 1 1WCM90 1 154744852 156956017 0.0789 0.2529 1.1916 1.1916 1 1 WCM90 1156957597 159785345 −0.0394 −0.1036 1.4074 0.454 1 0 WCM90 1 159785453198288709 −0.1433 −0.4775 1.3096 0.1268 1 0 WCM90 1 198492696 2492139640.0834 0.2657 1.2022 1.2022 1 1 WCM90 10 225982 135477891 −0.0763−0.2288 1.5384 0.1683 2 0 WCM90 11 193201 134605906 0.0203 0.0837 1.05971.0597 1 1 WCM90 12 148576 121603118 0.0293 0.1107 1.0797 1.0797 1 1WCM90 12 121603856 133810703 −0.1651 −0.5657 0.8969 0.4544 1 0 WCM90 1319041994 19751794 −0.0119 −0.0153 1.6746 0.3042 2 0 WCM90 13 1975239264413947 −0.0321 −0.0799 1.8767 0.0156 2 0 WCM90 13 64415622 115089411−0.1973 −0.704 1.0165 0.2113 1 0 WCM90 14 19110374 107283269 −0.0626−0.1814 0.8819 0.8819 1 1 WCM90 15 20083896 102514159 −0.1002 −0.31390.8045 0.8045 1 1 WCM90 16 67570 90260461 0.1226 0.3716 1.2938 1.2938 11 WCM90 17 131595 21030347 −0.2271 −0.8421 0.8449 0.2708 1 0 WCM90 1721075425 81187855 0.0033 0.0319 1.0224 1.0224 1 1 WCM90 18 4779078005150 −0.0149 −0.025 0.9828 0.9828 1 1 WCM90 19 104937 24116208−0.0221 −0.0478 0.9674 0.9674 1 1 WCM90 19 24116307 38946014 0.27690.7482 1.7482 1.6113 2 2 WCM90 19 38946182 49639242 −0.2136 −0.77810.946 0.2202 1 0 WCM90 19 49639948 57176482 0.3253 0.8555 2.4625 1.15632 1 WCM90 19 57176561 59093645 −0.083 −0.2522 0.8396 0.8396 1 1 WCM90 241670 118579684 0.0211 0.0862 1.0616 1.0616 1 1 WCM90 2 118582099166536072 −0.2042 −0.735 1.0315 0.1701 1 0 WCM90 2 166536619 2430370220.0763 0.2457 1.1857 1.1857 1 1 WCM90 20 68342 62934541 0.3128 0.82831.7756 1.7756 2 2 WCM90 21 9590314 48084201 −0.0553 −0.1567 0.89710.8971 1 1 WCM90 22 16159060 51219129 −0.014 −0.0219 0.9849 0.9849 1 1WCM90 3 239495 197896711 0.0379 0.136 1.0989 1.0989 1 1 WCM90 4 53469139140567 0.0284 0.1079 1.0777 1.0777 1 1 WCM90 4 139144360 1456560890.3399 0.8872 2.1595 1.5395 2 2 WCM90 4 145658878 190904471 0.05480.1848 1.1367 1.1367 1 1 WCM90 5 90697 21519594 −0.0243 −0.0548 0.96270.9627 1 1 WCM90 5 21734225 39721117 0.5234 1.2561 3.5574 1.2195 4 1WCM90 5 40681132 83525707 0.011 0.0554 1.0391 1.0391 1 1 WCM90 583549800 121767643 −0.21 −0.7616 1.0486 0.131 1 0 WCM90 5 121776301145583269 −0.0037 0.0101 1.007 1.007 1 1 WCM90 5 145598650 1538545570.1914 0.5466 1.4786 1.4427 1 1 WCM90 5 153854872 180687776 0.02290.0913 1.0653 1.0653 1 1 WCM90 6 203552 170892873 −0.0775 −0.233 1.56510.1367 2 0 WCM90 7 193254 20662947 0.2229 0.6227 1.9393 1.1403 2 1 WCM907 20666193 21985462 −0.2836 −1.1366 0.6793 0.2304 1 0 WCM90 7 22158277158937011 0.1256 0.3794 1.3145 1.2871 1 1 WCM90 8 163457 34181068−0.2508 −0.9596 0.662 0.3664 1 0 WCM90 8 34181122 43415879 0.4098 1.03323.223 0.8702 3 1 WCM90 8 47886271 52284471 −0.0075 −0.0016 NA NA NA NAWCM90 8 52287263 65495642 −0.1854 −0.6517 1.0397 0.2333 1 0 WCM90 865496059 146279508 0.0011 0.0251 1.0175 1.0175 1 1 WCM90 9 1485293976289 −0.092 −0.2842 0.8212 0.8212 1 1 WCM90 9 93976659 1204765910.0163 0.0716 1.0509 1.0509 1 1 WCM90 9 120476758 141107582 −0.1129−0.3608 0.7817 0.7759 1 1 WCM90 X 2700084 23899036 −0.1539 −0.5198 NA NANA NA WCM90 X 23928470 34150150 0.5292 1.267 NA NA NA NA WCM90 X34150365 64141724 0.0234 0.093 NA NA NA NA WCM90 X 64628306 693974921.2896 2.4729 NA NA NA NA WCM90 X 69419206 154493590 0.0489 0.1681 NA NANA NA WCM90_Z1_1 1 69649 152883866 −0.2031 0.58 1.9661 1.0236 2 1WCM90_Z1_1 1 152883967 153113093 1.0344 2.038 NA NA NA NA WCM90_Z1_1 1153122578 154680706 −0.2072 0.5748 NA NA NA NA WCM90_Z1_1 1 154685997155152403 0.2568 1.1487 NA NA NA NA WCM90_Z1_1 1 155154608 1556294610.6238 1.577 NA NA NA NA WCM90_Z1_1 1 155629741 157014097 0.1281 0.99372.0469 1.9356 2 2 WCM90_Z1_1 1 157062679 158943539 −0.6247 0.0108 1.94380.0712 2 0 WCM90_Z1_1 1 158984557 159785367 0.1674 1.0414 NA NA NA NAWCM90_Z1_1 1 159796728 198288550 −0.6066 0.0366 1.9767 0.0746 2 0WCM90_Z1_1 1 198492609 249212346 0.1837 1.061 2.1116 2.0613 2 2WCM90_Z1_1 10 225980 135440108 −0.2166 0.5627 2.8814 0.0726 3 0WCM90_Z1_1 11 193105 51412327 −0.2117 0.569 1.8812 1.0858 2 1 WCM90_Z1_111 51515549 82874879 0.0939 0.9521 1.9347 1.9347 2 2 WCM90_Z1_1 1182875318 134856563 −0.206 0.5764 1.9787 1.0035 2 1 WCM90_Z1_1 12 148811121660769 −0.0846 0.7309 1.9186 1.4007 2 1 WCM90_Z1_1 12 121660819133254263 −0.5721 0.0852 2.0245 0.0972 2 0 WCM90_Z1_1 12 133256215133810703 0.0077 0.846 2.1248 1.4703 2 1 WCM90_Z1_1 13 19600475 63745832−0.1709 0.6213 2.9781 0.0986 3 0 WCM90_Z1_1 13 66540556 115089411−0.5764 0.0792 2.0439 0.0689 2 0 WCM90_Z1_1 14 19377692 107283183−0.0516 0.7723 1.7315 1.6845 2 2 WCM90_Z1_1 15 20170150 52179801 −0.53570.136 1.1844 1.0133 1 1 WCM90_Z1_1 15 52181305 102517662 −0.1803 0.60931.9828 1.0683 2 1 WCM90_Z1_1 16 67604 90233627 0.3683 1.2807 2.92981.9294 3 2 WCM90_Z1_1 17 131595 535990 −0.7536 −0.1766 NA NA NA NAWCM90_Z1_1 17 556546 21092139 −0.6016 0.0436 1.9836 0.0778 2 0WCM90_Z1_1 17 21094369 21826154 −0.6865 −0.0782 1.2417 0.6528 1 1WCM90_Z1_1 17 22023461 30469681 0.0923 0.9501 1.9721 1.8919 2 2WCM90_Z1_1 17 30498088 32483536 −0.626 0.009 NA NA NA NA WCM90_Z1_1 1732582389 36104713 0.0869 0.9435 2.0032 1.8433 2 2 WCM90_Z1_1 17 3610480337791860 −0.6012 0.0442 NA NA NA NA WCM90_Z1_1 17 37809842 810834550.0884 0.9454 1.9445 1.9068 2 2 WCM90_Z1_1 18 48221 28611071 0.24351.1328 2.2557 2.1299 2 2 WCM90_Z1_1 18 28612171 78005224 0.0205 0.86191.8512 1.7838 2 2 WCM90_Z1_1 19 281498 1997375 −0.5693 0.0891 1.1950.9324 1 1 WCM90_Z1_1 19 2015394 4117620 0.042 0.8884 2.6763 1.0258 3 1WCM90_Z1_1 19 4153746 9091804 −0.5509 0.1149 1.1131 1.0527 1 1WCM90_Z1_1 19 9203936 10169300 −0.2004 0.5836 1.8879 1.1093 2 1WCM90_Z1_1 19 10169651 10362937 0.3178 1.2211 NA NA NA NA WCM90_Z1_1 1910363335 10690481 −0.5122 0.1686 NA NA NA NA WCM90_Z1_1 19 1069200017004032 −0.1998 0.5843 1.856 1.1427 2 1 WCM90_Z1_1 19 17004058 17015357−0.392 0.3322 NA NA NA NA WCM90_Z1_1 19 17017878 23836108 0.0475 0.89521.9011 1.8187 2 2 WCM90_Z1_1 19 23836322 35258308 0.5398 1.4806 3.57282.0083 4 2 WCM90_Z1_1 19 35260442 36582353 0.8601 1.8443 5.3352 1.8464 52 WCM90_Z1_1 19 36583658 38943505 0.7184 1.6847 4.6648 1.7647 5 2WCM90_Z1_1 19 38946094 49622216 −0.6582 −0.0372 1.9062 0.0429 2 0WCM90_Z1_1 19 49631250 57089394 0.8602 1.8444 5.428 1.7541 5 2WCM90_Z1_1 19 57089812 59083988 0.0625 0.9136 1.9253 1.8421 2 2WCM90_Z1_1 2 41613 60773427 0.1208 0.9849 1.996 1.9623 2 2 WCM90_Z1_1 260983613 61713061 −0.5858 0.066 NA NA NA NA WCM90_Z1_1 2 61715313116599804 0.0993 0.9586 1.9435 1.9435 2 2 WCM90_Z1_1 2 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122139280 −0.6289 0.0048 1.937 0.0697 2 0WCM90_Z1_1 5 122143973 141059972 0.0777 0.9322 1.9619 1.8544 2 2WCM90_Z1_1 5 141233942 154065351 0.3209 1.2249 2.838 1.8367 3 2WCM90_Z1_1 5 154092647 170395289 −0.2083 0.5734 1.812 1.1641 2 1WCM90_Z1_1 5 170395724 179071866 0.3697 1.2824 2.7872 2.0777 3 2WCM90_Z1_1 5 179078329 180687769 −0.2074 0.5746 1.8728 1.1057 2 1WCM90_Z1_1 6 203588 367352 0.2031 1.0844 NA NA NA NA WCM90_Z1_1 6 39332375994343 −0.183 0.6059 2.9595 0.0844 3 0 WCM90_Z1_1 6 76005656 105850757−0.308 0.4437 2.6121 0.108 3 0 WCM90_Z1_1 6 106536118 170893408 −0.01020.8238 3.4806 0.0595 3 0 WCM90_Z1_1 7 193451 15240972 0.4051 1.32393.946 1.0609 4 1 WCM90_Z1_1 7 15346160 20449577 0.1963 1.0762 NA NA NANA WCM90_Z1_1 7 20662957 22162118 −1.0665 −0.6696 NA NA NA NA WCM90_Z1_17 22165242 38783060 0.233 1.1202 3.1263 1.2214 3 1 WCM90_Z1_1 7 3878518738869884 −0.9957 −0.5524 NA NA NA NA WCM90_Z1_1 7 38870816 559857590.1901 1.0688 3.1511 1.0442 3 1 WCM90_Z1_1 7 55990881 117365164 0.47721.4081 2.7001 2.6076 3 3 WCM90_Z1_1 7 117368316 158937400 0.1437 1.01272.0568 1.9786 2 2 WCM90_Z1_1 8 190906 33454845 −0.9825 −0.531 1.2670.1172 1 0 WCM90_Z1_1 8 35406847 43211967 0.9549 1.9499 6.4432 1.284 6 1WCM90_Z1_1 8 47752739 50449716 −0.0271 0.8028 NA NA NA NA WCM90_Z1_1 851306797 65528834 −0.4915 0.1971 2.2394 0.0534 2 0 WCM90_Z1_1 8 65536969146279510 −0.025 0.8054 2.2264 1.2689 2 1 WCM90_Z1_1 9 17075 141111414−0.2245 0.5525 1.8495 1.0838 2 1 WCM90_Z1_1 X 2707709 8993583 0.04520.8923 NA NA NA NA WCM90_Z1_1 X 8996004 23892569 −0.5551 0.109 NA NA NANA WCM90_Z1_1 X 23897107 29417325 0.4638 1.3924 NA NA NA NA WCM90_Z1_1 X29592467 33229421 1.4519 2.4929 NA NA NA NA WCM90_Z1_1 X 3414818664196239 0.0418 0.8881 NA NA NA NA WCM90_Z1_1 X 64708914 69397495 2.26063.3479 NA NA NA NA WCM90_Z1_1 X 69419206 154509348 0.0568 0.9066 NA NANA NA WCM90_Z19_1 1 69634 157014097 0.0018 0.0292 1.0372 1.0037 1 1WCM90_Z19_1 1 157062614 198700746 −0.2376 −0.9781 1.0616 −0.0463 1 0WCM90_Z19_1 1 198701436 249212341 −0.0066 0.0012 1.0009 1.0009 1 1WCM90_Z19_1 10 225979 135440080 −0.0044 0.0086 2.0311 −0.0192 2 0WCM90_Z19_1 11 193097 134856626 −0.0958 −0.3199 1.124 0.4783 1 0WCM90_Z19_1 12 148675 121659917 0.0085 0.0511 1.0562 1.0158 1 1WCM90_Z19_1 12 121660769 133254282 −0.2072 −0.816 1.1193 0.0168 1 0WCM90_Z19_1 12 133256218 133810703 0.0705 0.2435 1.3668 1.001 1 1WCM90_Z19_1 13 19600515 63745832 −0.1018 −0.3436 1.7401 −0.164 2 0WCM90_Z19_1 13 66540556 115089411 −0.2587 −1.1003 0.8948 0.0381 1 0WCM90_Z19_1 14 19377727 107283091 −0.0015 0.0182 1.0361 0.9893 1 1WCM90_Z19_1 15 20170150 102517678 −0.0556 −0.1687 0.9251 0.8542 1 1WCM90_Z19_1 16 67604 90233626 0.1494 0.4663 1.4299 1.3333 1 1WCM90_Z19_1 17 131595 25628910 −0.2045 −0.8019 1.0649 0.0823 1 0WCM90_Z19_1 17 25630569 36099545 0.0321 0.1264 1.1498 1.0333 1 1WCM90_Z19_1 17 36104698 37785430 −0.2331 −0.9532 NA NA NA NA WCM90_Z19_117 37785802 81083419 0.0407 0.1532 1.1465 1.0776 1 1 WCM90_Z19_1 1848235 2954511 −0.1735 −0.6512 1.3199 −0.0464 1 0 WCM90_Z19_1 18 296070833555048 0.0588 0.2086 1.2253 1.0858 1 1 WCM90_Z19_1 18 3355753478005224 −0.1356 −0.4825 1.2767 0.1547 1 0 WCM90_Z19_1 19 28153424309552 −0.0137 −0.0225 1.0177 0.9514 1 1 WCM90_Z19_1 19 2430978238943459 0.291 0.8194 2.7114 0.8181 3 1 WCM90_Z19_1 19 38945965 49622280−0.2785 −1.2236 0.8148 0.0416 1 0 WCM90_Z19_1 19 49631346 570363810.3691 0.9947 3.1996 0.7857 3 1 WCM90_Z19_1 19 57036653 59083968 −0.0217−0.0498 1.0222 0.91 1 1 WCM90_Z19_1 2 41613 114715011 0.0067 0.04511.0486 1.015 1 1 WCM90_Z19_1 2 115200374 166771711 −0.2426 −1.00631.0442 −0.0486 1 0 WCM90_Z19_1 2 166773971 183902737 −0.0055 0.00491.0034 1.0034 1 1 WCM90_Z19_1 2 183943812 242813150 0.1332 0.4225 1.3881.2925 1 1 WCM90_Z19_1 2 242814009 242946607 −0.1962 −0.7604 NA NA NA NAWCM90_Z19_1 20 68406 62904861 0.3788 1.0158 2.022 2.022 2 2 WCM90_Z19_121 9907313 48084282 −0.0061 0.0029 1.0621 0.942 1 1 WCM90_Z19_1 2217063496 51219138 −0.0775 −0.2498 0.8728 0.8093 1 1 WCM90_Z19_1 3 239347197894726 0.0092 0.0533 1.0376 1.0376 1 1 WCM90_Z19_1 4 59404 190426459−0.0155 −0.0286 1.0135 0.9472 1 1 WCM90_Z19_1 5 140579 83362279−1.00E−04 0.023 1.0395 0.9926 1 1 WCM90_Z19_1 5 83402477 122426238−0.2786 −1.2243 0.9471 −0.0911 1 0 WCM90_Z19_1 5 122435582 1455229870.0211 0.0916 1.1369 0.9942 1 1 WCM90_Z19_1 5 145524050 154092578 0.21860.6456 1.7631 1.3656 2 1 WCM90_Z19_1 5 154135401 170395343 0.0183 0.08251.1742 0.9435 1 1 WCM90_Z19_1 5 170395731 179229105 0.2476 0.7167 2.02121.2656 2 1 WCM90_Z19_1 5 179248027 180687776 −0.0166 −0.0323 1.05730.8984 1 1 WCM90_Z19_1 6 203588 170893438 −0.118 −0.4089 1.5403 −0.03392 0 WCM90_Z19_1 7 193245 11441553 0.1959 0.5883 1.6224 1.3845 2 1WCM90_Z19_1 7 11446060 40027425 0.0193 0.0859 1.1496 0.9731 1 1WCM90_Z19_1 7 40027611 103824602 0.202 0.6036 2.0628 0.9763 2 1WCM90_Z19_1 7 103828827 126249446 −0.0283 −0.0721 1.0859 0.8166 1 1WCM90_Z19_1 7 126341876 129690318 0.2201 0.6492 1.8492 1.2874 2 1WCM90_Z19_1 7 129691167 137597573 −0.0217 −0.0496 1.1411 0.7913 1 1WCM90_Z19_1 7 137600739 158937400 0.2065 0.6152 2.0806 0.9829 2 1WCM90_Z19_1 8 190907 51314769 0.0314 0.1241 1.1514 1.0282 1 1WCM90_Z19_1 8 51351139 65536982 −0.2489 −1.0426 1.0041 −0.0332 1 0WCM90_Z19_1 8 66439766 146279507 0.0233 0.0987 1.0708 1.0708 1 1WCM90_Z19_1 9 17086 1051973 −0.3758 −2.0109 0.4082 0.0881 0 0WCM90_Z19_1 9 1053739 6814636 −0.1192 −0.4139 0.9572 0.544 1 1WCM90_Z19_1 9 6849614 28863675 −0.3277 −1.5751 0.5064 0.1648 1 0WCM90_Z19_1 9 32384732 38595673 −0.1149 −0.3964 0.834 0.6855 1 1WCM90_Z19_1 9 38596201 79118585 −0.3913 −2.1812 0.4989 −0.0579 0 0WCM90_Z19_1 9 79234286 110249505 −0.1509 −0.5487 0.9702 0.397 1 0WCM90_Z19_1 9 110249584 122004387 −0.3756 −2.0086 0.3156 0.1814 0 0WCM90_Z19_1 9 122011331 134889825 −0.0891 −0.2941 0.8974 0.7337 1 1WCM90_Z19_1 9 134949107 141111414 −0.3234 −1.5411 0.4427 0.2446 0 0WCM90_Z19_1 X 2707711 154509348 −0.0358 −0.0985 NA NA NA NA WCM90_Z21_11 69635 152883816 −0.3165 −0.3909 1.0094 0.516 1 1 WCM90_Z21_1 1152883957 153113025 0.9887 1.1283 NA NA NA NA WCM90_Z21_1 1 153122393154698473 −0.318 −0.3927 NA NA NA NA WCM90_Z21_1 1 154728827 1556295350.4515 0.5288 1.657 1.2286 2 1 WCM90_Z21_1 1 155629762 156628006 −0.0036−0.0044 NA NA NA NA WCM90_Z21_1 1 156628475 157014097 0.2968 0.3507 NANA NA NA WCM90_Z21_1 1 157062657 158943505 −0.6737 −0.8612 1.0739 0.02711 0 WCM90_Z21_1 1 158984681 159785346 0.3159 0.3728 NA NA NA NAWCM90_Z21_1 1 159796693 198288563 −0.7477 −0.9638 1.0422 −0.0168 1 0WCM90_Z21_1 1 198492616 249212434 0.2689 0.3183 1.4602 1.0334 1 1WCM90_Z21_1 10 225981 135440081 −0.3268 −0.4039 1.5214 −0.0098 2 0WCM90_Z21_1 11 193097 134856556 −0.0039 −0.0047 1.004 0.9896 1 1WCM90_Z21_1 12 148675 34179683 −0.02 −0.0242 0.9858 0.981 1 1WCM90_Z21_1 12 34182559 41582590 0.4564 0.5343 1.893 1.0036 2 1WCM90_Z21_1 12 41582881 46756340 0.054 0.0649 1.0998 0.9922 1 1WCM90_Z21_1 12 46756890 48240146 0.4203 0.4932 NA NA NA NA WCM90_Z21_112 48240461 50500104 −0.0055 −0.0067 1.0482 0.9426 1 1 WCM90_Z21_1 1250500746 52470833 0.4357 0.5107 1.9413 0.9082 2 1 WCM90_Z21_1 1252565235 52914037 0.8261 0.9495 2.7385 1.1237 3 1 WCM90_Z21_1 1252938364 54350229 0.4906 0.5734 1.9975 0.9784 2 1 WCM90_Z21_1 1254367154 57843532 −0.0289 −0.0349 0.995 0.9572 1 1 WCM90_Z21_1 1257843737 71077926 0.5331 0.6217 2.0861 0.9912 2 1 WCM90_Z21_1 1271078517 85285862 −0.0343 −0.0414 1.0188 0.9247 1 1 WCM90_Z21_1 1285408291 96422886 0.5256 0.6131 2.1955 0.8635 2 1 WCM90_Z21_1 1296429295 98850629 −0.0422 −0.051 NA NA NA NA WCM90_Z21_1 12 98880948111052034 0.4927 0.5758 2.0449 0.9361 2 1 WCM90_Z21_1 12 111057639112844686 0.8018 0.9226 NA NA NA NA WCM90_Z21_1 12 112846128 1188522360.4366 0.5117 1.8399 1.0116 2 1 WCM90_Z21_1 12 119419708 121660770−0.0206 −0.0248 1.0221 0.9438 1 1 WCM90_Z21_1 12 121660838 123110771−0.7222 −0.9282 1.0616 −0.0106 1 0 WCM90_Z21_1 12 123186730 1332527580.0079 0.0096 2.0073 0.006 2 0 WCM90_Z21_1 12 133253159 133810703 0.50710.5921 2.0828 0.9321 2 1 WCM90_Z21_1 13 19600475 63745832 −0.2965−0.3656 1.5335 0.0188 2 0 WCM90_Z21_1 13 66540556 115089411 −0.7471−0.963 1.0262 −2.00E−04  1 0 WCM90_Z21_1 14 19377727 107283197 −0.1298−0.1579 0.9822 0.8104 1 1 WCM90_Z21_1 15 20170150 102517666 −0.3218−0.3976 1.0088 0.5095 1 1 WCM90_Z21_1 16 67604 1004554 0.4095 0.48071.8195 0.9714 2 1 WCM90_Z21_1 16 1004658 3724437 0.2111 0.2508 1.38230.9974 1 1 WCM90_Z21_1 16 3725395 50138915 0.3968 0.4662 1.7637 0.9991 21 WCM90_Z21_1 16 50186890 90233622 0.1028 0.1229 1.2429 0.935 1 1WCM90_Z21_1 17 131595 21208370 −0.7526 −0.9706 1.0188 0.0019 1 0WCM90_Z21_1 17 21215537 30469651 0.0176 0.0211 1.0465 0.983 1 1WCM90_Z21_1 17 30498106 32483427 −0.6863 −0.8786 NA NA NA NA WCM90_Z21_117 32582389 36104728 0.0224 0.0269 1.0947 0.943 1 1 WCM90_Z21_1 1736104800 37809839 −0.7965 −1.0325 NA NA NA NA WCM90_Z21_1 17 3781328581083419 0.0159 0.0191 1.0341 0.9926 1 1 WCM90_Z21_1 18 48206 780051990.0086 0.0103 1.0278 0.9866 1 1 WCM90_Z21_1 19 281405 1997366 −0.2703−0.3325 1.0479 0.5404 1 1 WCM90_Z21_1 19 2015393 4117566 0.2506 0.2971.3963 1.0608 1 1 WCM90_Z21_1 19 4153748 9091814 −0.3252 −0.402 0.99150.5222 1 1 WCM90_Z21_1 19 9204111 10166375 0.0478 0.0574 1.0717 1.0094 11 WCM90_Z21_1 19 10169265 10362938 0.5585 0.6504 NA NA NA NA WCM90_Z21_119 10363286 10394239 0.0565 0.0678 NA NA NA NA WCM90_Z21_1 19 1039445210685607 −0.359 −0.445 NA NA NA NA WCM90_Z21_1 19 10687990 24310734−0.0013 −0.0015 1.0158 0.9821 1 1 WCM90_Z21_1 19 29567134 305064550.8262 0.9496 NA NA NA NA WCM90_Z21_1 19 30934584 35256531 0.5011 0.58531.9675 1.0331 2 1 WCM90_Z21_1 19 35258264 36582353 0.8431 0.9683 2.97880.9342 3 1 WCM90_Z21_1 19 36583651 38056745 0.5212 0.6081 1.915 1.1335 21 WCM90_Z21_1 19 38057059 38943512 0.8629 0.9902 2.9681 1.0047 3 1WCM90_Z21_1 19 38946112 49631306 −0.7833 −1.0139 0.9999 −0.0095 1 0WCM90_Z21_1 19 49631653 57132937 0.8682 0.996 2.982 1.007 3 1WCM90_Z21_1 19 57133421 59083923 0.0064 0.0077 1.0054 1.0054 1 1WCM90_Z21_1 2 41620 60773167 0.0261 0.0314 1.0318 1.0122 1 1 WCM90_Z21_12 60773434 61715377 −0.7316 −0.9413 NA NA NA NA WCM90_Z21_1 2 61715763116599847 0.0191 0.023 1.0307 1.0014 1 1 WCM90_Z21_1 2 118572371166605395 −0.7438 −0.9583 1.0385 −0.0091 1 0 WCM90_Z21_1 2 166606327242946604 0.0337 0.0405 1.0383 1.0186 1 1 WCM90_Z21_1 20 68406 373567640.8223 0.9453 1.9256 1.9256 2 2 WCM90_Z21_1 20 37356993 48894078 0.68860.7966 1.9408 1.5331 2 2 WCM90_Z21_1 20 48894756 49199249 0.8618 0.989NA NA NA NA WCM90_Z21_1 20 49202351 62904845 1.007 1.1483 2.294 2.139 22 WCM90_Z21_1 21 9907301 48084210 −0.0285 −0.0344 0.9906 0.9623 1 1WCM90_Z21_1 22 17063496 51219138 −0.1132 −0.1376 0.9247 0.8935 1 1WCM90_Z21_1 3 239347 85984969 0.0155 0.0187 1.0203 1.0057 1 1WCM90_Z21_1 3 86010733 197894726 0.2486 0.2947 1.4585 0.9947 1 1WCM90_Z21_1 4 59331 126428439 0.0146 0.0176 1.0123 1.0123 1 1WCM90_Z21_1 4 128544639 130032843 −0.7809 −1.0105 NA NA NA NAWCM90_Z21_1 4 133357010 190426459 −0.0017 −0.0021 1.0286 0.9685 1 1WCM90_Z21_1 5 140560 26915966 −0.3162 −0.3905 0.9477 0.578 1 1WCM90_Z21_1 5 26916024 35702306 0.8106 0.9323 2.8191 0.9976 3 1WCM90_Z21_1 5 35704684 39394363 1.2252 1.3851 4.0934 1.1303 4 1WCM90_Z21_1 5 40681254 50137815 −0.3649 −0.4525 0.9179 0.5437 1 1WCM90_Z21_1 5 50679527 82849325 0.0155 0.0186 1.0313 0.9947 1 1WCM90_Z21_1 5 82850775 121799209 −0.7467 −0.9623 1.0396 −0.0131 1 0WCM90_Z21_1 5 122131040 141059944 0.0196 0.0236 1.058 0.975 1 1WCM90_Z21_1 5 141233873 154065351 0.2714 0.3212 1.4414 1.0575 1 1WCM90_Z21_1 5 154092634 170395475 −0.3084 −0.3806 1.0104 0.5259 1 1WCM90_Z21_1 5 170395724 179079306 0.2957 0.3495 1.5107 1.0375 2 1WCM90_Z21_1 5 179105658 180687773 −0.2876 −0.3542 1.0113 0.5533 1 1WCM90_Z21_1 6 203542 74533254 −0.2958 −0.3647 1.55 0.0032 2 0WCM90_Z21_1 6 74537868 105850763 −0.7 −0.8975 1.0767 −0.0031 1 0WCM90_Z21_1 6 106536255 170893411 −0.2969 −0.366 1.5488 0.0031 2 0WCM90_Z21_1 7 193451 20449251 0.5614 0.6537 2.1474 0.9989 2 1WCM90_Z21_1 7 20449551 21985424 −0.7559 −0.9752 NA NA NA NA WCM90_Z21_17 22162085 38783051 0.3823 0.4495 1.7079 1.0232 2 1 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WCM90_Z21_1 X 9621705 23899036 −0.7767−1.0046 NA NA NA NA WCM90_Z21_1 X 23933912 29417279 0.4557 0.5336 NA NANA NA WCM90_Z21_1 X 29592467 33229421 2.1223 2.3336 NA NA NA NAWCM90_Z21_1 X 34148248 64196239 −0.0306 −0.0369 NA NA NA NA WCM90_Z21_1X 64708855 69397504 3.2113 3.4534 NA NA NA NA WCM90_Z21_1 X 69419227154509348 −0.0265 −0.032 NA NA NA NA WCM90_Z25_1 1 69569 157014089−0.088 NA NA NA NA NA WCM90_Z25_1 1 157062660 198262160 −0.2206 NA NA NANA NA WCM90_Z25_1 1 198288614 249212373 −0.0849 NA NA NA NA NAWCM90_Z25_1 10 225989 135440105 −0.0347 NA NA NA NA NA WCM90_Z25_1 11193102 134856592 −0.0836 NA NA NA NA NA WCM90_Z25_1 12 148644 1216668680.0269 NA NA NA NA NA WCM90_Z25_1 12 121670294 133254258 −0.1948 NA NANA NA NA WCM90_Z25_1 12 133256230 133810703 0.0154 NA NA NA NA NAWCM90_Z25_1 13 19600475 61988094 −0.0994 NA NA NA NA NA WCM90_Z25_1 1361989235 115028480 −0.2218 NA NA NA NA NA WCM90_Z25_1 13 115030714115089411 −0.1064 NA NA NA NA NA WCM90_Z25_1 14 19377733 1072830960.0227 NA NA NA NA NA WCM90_Z25_1 15 20170150 102517667 −0.0177 NA NA NANA NA WCM90_Z25_1 16 67604 90233622 0.1282 NA NA NA NA NA WCM90_Z25_1 17131595 25637146 −0.1972 NA NA NA NA NA WCM90_Z25_1 17 25639374 363581240.0131 NA NA NA NA NA WCM90_Z25_1 17 36358956 37785473 −0.2225 NA NA NANA NA WCM90_Z25_1 17 37785806 81083419 0.0372 NA NA NA NA NA WCM90_Z25_118 48241 2960731 −0.1678 NA NA NA NA NA WCM90_Z25_1 18 2982674 332896600.0462 NA NA NA NA NA WCM90_Z25_1 18 33484800 78005210 −0.1224 NA NA NANA NA WCM90_Z25_1 19 281403 24309680 −0.0722 NA NA NA NA NA WCM90_Z25_119 24310032 38943505 0.2351 NA NA NA NA NA WCM90_Z25_1 19 3894598849631284 −0.3473 NA NA NA NA NA WCM90_Z25_1 19 49631641 57134012 0.3238NA NA NA NA NA WCM90_Z25_1 19 57157110 59083985 −0.0744 NA NA NA NA NAWCM90_Z25_1 2 41620 114709329 0.0251 NA NA NA NA NA WCM90_Z25_1 2114713215 166611485 −0.2117 NA NA NA NA NA WCM90_Z25_1 2 166613648187625926 0.0237 NA NA NA NA NA WCM90_Z25_1 2 187626338 242946607 0.1441NA NA NA NA NA WCM90_Z25_1 20 68373 62904925 0.2777 NA NA NA NA NAWCM90_Z25_1 21 9907280 48084210 0.0203 NA NA NA NA NA WCM90_Z25_1 2217063431 51219138 −0.0854 NA NA NA NA NA WCM90_Z25_1 3 239347 1978947200.017 NA NA NA NA NA WCM90_Z25_1 4 59388 190426471 0.0026 NA NA NA NA NAWCM90_Z25_1 5 140627 83402577 0.0115 NA NA NA NA NA WCM90_Z25_1 583433096 121786790 −0.2443 NA NA NA NA NA WCM90_Z25_1 5 121787002141024595 0.0318 NA NA NA NA NA WCM90_Z25_1 5 141024710 153857077 0.2211NA NA NA NA NA WCM90_Z25_1 5 153857407 170834720 0.0606 NA NA NA NA NAWCM90_Z25_1 5 170837557 179079332 0.2535 NA NA NA NA NA WCM90_Z25_1 5179105616 180687766 −0.0144 NA NA NA NA NA WCM90_Z25_1 6 203509170893450 −0.0972 NA NA NA NA NA WCM90_Z25_1 7 193253 20449362 0.2074 NANA NA NA NA WCM90_Z25_1 7 20449607 22179676 −0.199 NA NA NA NA NAWCM90_Z25_1 7 22184676 26893772 0.2315 NA NA NA NA NA WCM90_Z25_1 726903991 39046460 −0.0224 NA NA NA NA NA WCM90_Z25_1 7 39125461103828761 0.2196 NA NA NA NA NA WCM90_Z25_1 7 103835685 124533800−0.0303 NA NA NA NA NA WCM90_Z25_1 7 126079219 129663496 0.2531 NA NA NANA NA WCM90_Z25_1 7 129664312 137588758 −0.001 NA NA NA NA NAWCM90_Z25_1 7 137590592 158937400 0.2236 NA NA NA NA NA WCM90_Z25_1 8190900 50449806 0.0852 NA NA NA NA NA WCM90_Z25_1 8 51306825 66439640−0.2181 NA NA NA NA NA WCM90_Z25_1 8 66516719 146279508 0.0805 NA NA NANA NA WCM90_Z25_1 9 17086 745226 −0.3743 NA NA NA NA NA WCM90_Z25_1 9842048 38543273 −0.1386 NA NA NA NA NA WCM90_Z25_1 9 38572051 79118447−0.3657 NA NA NA NA NA WCM90_Z25_1 9 79118585 111617184 −0.1266 NA NA NANA NA WCM90_Z25_1 9 111617341 121929811 −0.3428 NA NA NA NA NAWCM90_Z25_1 9 121930197 134473918 −0.0793 NA NA NA NA NA WCM90_Z25_1 9134477459 141111414 −0.3054 NA NA NA NA NA WCM90_Z25_1 X 2707688154509348 −0.0107 NA NA NA NA NA WCM90_Z29_1 1 69603 154687414 −0.10160.613 2.0458 1.0131 2 1 WCM90_Z29_1 1 154698431 155152376 0.1867 1.34 NANA NA NA WCM90_Z29_1 1 155154668 155629629 0.4475 1.859 NA NA NA NAWCM90_Z29_1 1 155629743 157014113 0.0606 1.0485 2.2609 1.8757 2 2WCM90_Z29_1 1 157062685 198700804 −0.2817 −0.0031 2.0173 −0.0216 2 0WCM90_Z29_1 1 198701643 249212388 0.0547 1.0342 2.0479 2.0479 2 2WCM90_Z29_1 10 225952 135440086 −0.1201 0.5577 3.0594 −0.1156 3 0WCM90_Z29_1 11 193097 2016846 −0.1464 0.4762 2.423 0.3592 2 0WCM90_Z29_1 11 2017122 49229962 −0.2359 0.1722 1.1722 1.0814 1 1WCM90_Z29_1 11 49598081 61404455 −0.1289 0.5306 2.1245 0.7645 2 1WCM90_Z29_1 11 61404866 82880683 0.0819 1.1002 2.1593 2.1284 2 2WCM90_Z29_1 11 82880850 82938815 −0.2558 0.0981 NA NA NA NA WCM90_Z29_111 82947489 96124759 −0.0955 0.6311 2.2265 0.871 2 1 WCM90_Z29_1 1196124891 134856563 −0.2776 0.0134 2.0959 −0.0772 2 0 WCM90_Z29_1 12148644 121666646 0.0616 1.0509 2.1226 2.0212 2 2 WCM90_Z29_1 12121666868 133254274 −0.2595 0.084 2.1236 −0.0038 2 0 WCM90_Z29_1 12133256221 133810703 0.1253 1.2022 2.656 1.9457 3 2 WCM90_Z29_1 1319600475 115089411 −0.2244 0.2141 2.3081 0.0118 2 0 WCM90_Z29_1 1419377710 107283210 0.0474 1.0161 2.0727 1.9723 2 2 WCM90_Z29_1 1520170150 52258248 −0.2943 −0.0542 1.0344 0.8918 1 1 WCM90_Z29_1 1552258698 102517662 −0.1527 0.4562 1.8135 0.9304 2 1 WCM90_Z29_1 16 67604114934 0.148 1.2539 NA NA NA NA WCM90_Z29_1 16 115009 25258035 0.20851.3872 2.6831 2.5483 3 3 WCM90_Z29_1 16 25258450 90233622 0.1251 1.20173.0421 1.5581 3 2 WCM90_Z29_1 17 131595 21201719 −0.2694 0.0458 2.1129−0.0484 2 0 WCM90_Z29_1 17 21202191 36357236 0.0469 1.0147 2.1861 1.85472 2 WCM90_Z29_1 17 36358127 37785806 −0.2821 −0.0045 NA NA NA NAWCM90_Z29_1 17 37786257 81083419 0.0655 1.0605 2.1314 2.0399 2 2WCM90_Z29_1 18 48216 78005226 −0.0271 0.8233 1.8553 1.6836 2 2WCM90_Z29_1 19 281499 1990074 −0.232 0.1865 1.2414 1.0345 1 1WCM90_Z29_1 19 1990752 4171129 0.0555 1.036 3.192 0.9091 3 1 WCM90_Z29_119 4171445 9325126 −0.2677 0.0521 1.1054 0.9682 1 1 WCM90_Z29_1 199325252 17015340 −0.0727 0.6969 2.134 1.1081 2 1 WCM90_Z29_1 19 1701787821560270 0.0755 1.0847 2.2592 1.9827 2 2 WCM90_Z29_1 19 2158005124309712 −0.062 0.7273 2.554 0.757 3 1 WCM90_Z29_1 19 24310032 389435030.449 1.8617 5.3593 1.9095 5 2 WCM90_Z29_1 19 38945906 49631692 −0.2812−8.00E−04 1.9913 0.0076 2 0 WCM90_Z29_1 19 49632212 57157157 0.53672.018 6.1089 1.9916 6 2 WCM90_Z29_1 19 57158960 59083988 0.0673 1.06482.1989 1.985 2 2 WCM90_Z29_1 2 41609 60687690 0.0591 1.0449 2.06322.0632 2 2 WCM90_Z29_1 2 60687959 61715389 −0.1999 0.3 NA NA NA NAWCM90_Z29_1 2 61715779 116593770 0.0538 1.032 2.1154 1.9742 2 2WCM90_Z29_1 2 116594117 166535708 −0.2574 0.0921 2.1759 −0.0441 2 0WCM90_Z29_1 2 166535918 242946607 0.0474 1.016 2.0524 1.9922 2 2WCM90_Z29_1 20 68397 62904890 0.5009 1.9551 3.8773 3.8773 4 4WCM90_Z29_1 21 9907291 48084277 −0.1123 0.5812 2.0176 0.9745 2 1WCM90_Z29_1 22 17063485 51219138 −0.0803 0.6754 2.0889 1.1051 2 1WCM90_Z29_1 3 239347 197894712 0.0471 1.0152 2.0512 1.991 2 2WCM90_Z29_1 4 59390 126411214 0.033 0.98 2.0072 1.9376 2 2 WCM90_Z29_1 4126411401 130032843 −0.2902 −0.0375 NA NA NA NA WCM90_Z29_1 4 133357020190426459 0.0436 1.0067 2.0794 1.9391 2 2 WCM90_Z29_1 5 140443 31294351−0.1401 0.496 1.4853 1.3353 1 1 WCM90_Z29_1 5 31297501 40681254 0.63932.1922 7.1209 2.0188 7 2 WCM90_Z29_1 5 40681530 83433096 0.0054 0.90951.976 1.7808 2 2 WCM90_Z29_1 5 83476228 122139220 −0.2905 −0.0386 1.87160.0756 2 0 WCM90_Z29_1 5 122143973 154065352 0.096 1.1338 2.2724 2.11652 2 WCM90_Z29_1 5 154092631 170380610 −0.0967 0.6276 1.8041 1.2859 2 1WCM90_Z29_1 5 170395368 179079358 0.1961 1.3604 2.8014 2.3337 3 2WCM90_Z29_1 5 179105614 180687776 −0.133 0.518 2.0924 0.7716 2 1WCM90_Z29_1 6 203615 57046862 −0.0966 0.6279 3.1225 −0.0319 3 0WCM90_Z29_1 6 57048783 106536261 −0.266 0.0588 1.9752 0.108 2 0WCM90_Z29_1 6 106543515 170893454 −0.1269 0.5367 3.0218 −0.1204 3 0WCM90_Z29_1 7 193222 14620521 0.4437 1.852 6.2739 0.9462 6 1 WCM90_Z29_17 14622748 20449617 0.2317 1.4366 NA NA NA NA WCM90_Z29_1 7 2066296121985409 −0.4412 −0.787 NA NA NA NA WCM90_Z29_1 7 22162090 1178769350.1663 1.2949 3.9262 0.9812 4 1 WCM90_Z29_1 7 117880031 158937375−0.1186 0.5622 1.9331 1.0199 2 1 WCM90_Z29_1 8 190908 33454982 −0.4785−1.035 1.0008 −0.0247 1 0 WCM90_Z29_1 8 35406923 43172516 0.4657 1.89216.0072 1.4164 6 1 WCM90_Z29_1 8 43173764 49987801 −0.062 0.7272 NA NA NANA WCM90_Z29_1 8 50449807 66439647 −0.2834 −0.0097 1.8798 0.1068 2 0WCM90_Z29_1 8 66516809 146279529 −0.0978 0.6242 1.9909 1.0918 2 1WCM90_Z29_1 9 17116 39078450 −0.1211 0.5547 2.1347 0.803 2 1 WCM90_Z29_19 39086729 141111414 −0.2656 0.0603 1.0872 0.9982 1 1 WCM90_Z29_1 X2707694 5811191 −0.0546 0.748 NA NA NA NA WCM90_Z29_1 X 5811678 23892572−0.2988 −0.0727 NA NA NA NA WCM90_Z29_1 X 23897107 29417278 0.251 1.4768NA NA NA NA WCM90_Z29_1 X 29592467 33229421 0.9459 2.6695 NA NA NA NAWCM90_Z29_1 X 34148186 64196239 0.0178 0.9415 NA NA NA NA WCM90_Z29_1 X64708913 69397514 1.7398 3.7259 NA NA NA NA WCM90_Z29_1 X 69419145154509348 −0.0033 0.8867 NA NA NA NA WCM91 1 15922 249213973 −0.0095 NANA NA NA NA WCM91 10 225958 135438943 −0.025 NA NA NA NA NA WCM91 11193096 134605959 −0.0225 NA NA NA NA NA WCM91 12 148468 133810788−0.0415 NA NA NA NA NA WCM91 13 19041937 115089411 −0.0409 NA NA NA NANA WCM91 14 19110239 107283213 −0.0406 NA NA NA NA NA WCM91 15 20083921102506257 0.0053 NA NA NA NA NA WCM91 16 67619 90260461 −0.0319 NA NA NANA NA WCM91 17 263028 81052545 −0.0344 NA NA NA NA NA WCM91 18 4773278005203 −0.0585 NA NA NA NA NA WCM91 19 105021 59093696 −0.0166 NA NANA NA NA WCM91 2 41612 243037103 −0.0208 NA NA NA NA NA WCM91 20 6834262934592 −0.0214 NA NA NA NA NA WCM91 21 9590271 48084175 −0.022 NA NANA NA NA WCM91 22 16159060 51219129 −0.0221 NA NA NA NA NA WCM91 3361470 197896800 −0.0239 NA NA NA NA NA WCM91 4 53403 190873327 −0.0231NA NA NA NA NA WCM91 5 90696 180687610 −0.0343 NA NA NA NA NA WCM91 6203535 170892854 −0.0356 NA NA NA NA NA WCM91 7 193222 158937104 −0.0247NA NA NA NA NA WCM91 8 166443 146279528 −0.0398 NA NA NA NA NA WCM91 9116931 141071668 −0.0092 NA NA NA NA NA WCM91 X 2700162 154493562−0.2438 NA NA NA NA NA WCM91_Z1_1 1 69603 9780597 0.0604 0.8091 2.49461.0097 2 1 WCM91_Z1_1 1 9780843 111964236 −0.1309 0.5784 1.9863 1 2 1WCM91_Z1_1 1 111965553 112991698 −0.5314 0.0709 NA NA NA NA WCM91_Z1_1 1112997110 116932317 −0.1402 0.567 1.9623 1.0005 2 1 WCM91_Z1_1 1116932921 116952766 −0.0259 0.7058 NA NA NA NA WCM91_Z1_1 1 117037377117603156 0.7842 1.6374 NA NA NA NA WCM91_Z1_1 1 117605058 1176222381.6651 2.5873 NA NA NA NA WCM91_Z1_1 1 117624586 118574329 0.9974 1.8716NA NA NA NA WCM91_Z1_1 1 118579398 118727707 0.8975 1.7623 NA NA NA NAWCM91_Z1_1 1 119427406 145096591 −0.1059 0.6089 NA NA NA NA WCM91_Z1_1 1145103947 151079544 0.8043 1.6595 4.5597 1.7587 5 2 WCM91_Z1_1 1151089888 152331302 1.1707 2.0597 6.3392 1.9989 6 2 WCM91_Z1_1 1152382077 152957970 −0.4309 0.2019 NA NA NA NA WCM91_Z1_1 1 152975619154243372 0.3234 1.1172 2.3219 2.0166 2 2 WCM91_Z1_1 1 154246028155162235 1.1087 1.9927 6.0457 1.9138 6 2 WCM91_Z1_1 1 155162615170959088 −0.402 0.2391 1.9855 0.375 2 0 WCM91_Z1_1 1 170961433174210796 0.1892 0.9612 1.9925 1.9013 2 2 WCM91_Z1_1 1 174219725178442258 −0.4483 0.1794 2.1526 0.1123 2 0 WCM91_Z1_1 1 178482329205689741 0.2137 0.9899 1.986 1.986 2 2 WCM91_Z1_1 1 205696890 207200892−0.5563 0.0381 2.0876 −0.0341 2 0 WCM91_Z1_1 1 207222546 2076533940.1785 0.9487 NA NA NA NA WCM91_Z1_1 1 207669702 207975820 −0.5982−0.0177 NA NA NA NA WCM91_Z1_1 1 207990748 213445936 0.214 0.9902 2.01891.954 2 2 WCM91_Z1_1 1 214170086 249212558 0.6289 1.4643 3.4954 2.0233 32 WCM91_Z1_1 10 226016 15902237 −0.5865 −0.002 1.0199 0.9773 1 1WCM91_Z1_1 10 16526397 17243618 −1.2683 −1.0088 0.9661 0.0278 1 0WCM91_Z1_1 10 17271587 50386260 −0.1087 0.6055 2.0204 1.0225 2 1WCM91_Z1_1 10 50396343 50740980 −0.6589 −0.0994 NA NA NA NA WCM91_Z1_110 50818812 60966553 0.2302 1.0091 2.0972 1.9283 2 2 WCM91_Z1_1 1060994064 61122227 −0.6964 −0.1505 NA NA NA NA WCM91_Z1_1 10 6141253888681437 0.2203 0.9975 2.0082 1.9849 2 2 WCM91_Z1_1 10 88683169 90122360−0.6158 −0.0412 NA NA NA NA WCM91_Z1_1 10 90332716 93558531 0.24731.0291 2.0407 2.0407 2 2 WCM91_Z1_1 10 93572874 95072891 −0.5851−2.00E−04 NA NA NA NA WCM91_Z1_1 10 95076498 135440081 −0.1244 0.58642.0152 0.9877 2 1 WCM91_Z1_1 11 193146 62886468 −0.1295 0.5801 2.00330.9867 2 1 WCM91_Z1_1 11 62886727 85367358 0.2085 0.9838 1.9777 1.9777 22 WCM91_Z1_1 11 85373391 134856597 0.205 0.9797 2.998 0.9462 3 1WCM91_Z1_1 12 148674 20896242 −0.2701 0.4062 2.6653 −0.0149 3 0WCM91_Z1_1 12 20903659 26231979 0.7914 1.6454 3.329 2.9275 3 3WCM91_Z1_1 12 26274965 76796498 −0.276 0.3988 2.6201 0.0168 3 0WCM91_Z1_1 12 76804371 121758193 0.4026 1.2082 2.3475 2.2735 2 2WCM91_Z1_1 12 122064924 122962804 −0.0276 0.7038 2.3018 0.9558 2 1WCM91_Z1_1 12 122964798 133810751 0.4006 1.2059 2.5734 2.0401 3 2WCM91_Z1_1 13 19600515 70681598 −0.5663 0.0248 2.0587 −0.024 2 0WCM91_Z1_1 13 72014808 72255975 −2.4292 −4.7173 NA NA NA NA WCM91_Z1_113 72440256 94938655 −0.5947 −0.013 1.9975 −0.0155 2 0 WCM91_Z1_1 1394958373 95735530 −2.3566 −4.1283 NA NA NA NA WCM91_Z1_1 13 95768240115089411 −0.5753 0.0129 2.0264 −0.0085 2 0 WCM91_Z1_1 14 19377703107283210 −0.2907 0.3803 1.6319 0.9714 2 1 WCM91_Z1_1 15 2017015083358196 −0.1374 0.5704 1.974 0.9958 2 1 WCM91_Z1_1 15 83378388 83561552−1.1962 −0.8902 NA NA NA NA WCM91_Z1_1 15 83657568 102506284 −0.13080.5785 1.9646 1.0221 2 1 WCM91_Z1_1 16 67604 90233299 0.0994 0.85542.6321 0.9865 3 1 WCM91_Z1_1 17 131595 6733672 0.1908 0.963 1.94941.9494 2 2 WCM91_Z1_1 17 6888795 8633488 −0.5848  2.00E−04 2.0229−0.0226 2 0 WCM91_Z1_1 17 8638480 10447278 0.2272 1.0056 2.0335 1.982 22 WCM91_Z1_1 17 10448738 19748662 −0.5948 −0.0131 1.9802 0.0017 2 0WCM91_Z1_1 17 19752713 43176872 0.2179 0.9948 2.0114 1.9742 2 2WCM91_Z1_1 17 43180331 44632740 −0.7355 −0.2045 NA NA NA NA WCM91_Z1_117 44770430 65212042 0.2098 0.9853 2.0075 1.952 2 2 WCM91_Z1_1 1765214766 81083419 −0.1301 0.5794 1.9767 1.0117 2 1 WCM91_Z1_1 18 4820078005224 −0.5714 0.0181 2.0409 −0.0157 2 0 WCM91_Z1_1 19 281424 8455333−0.5975 −0.0167 1.9997 −0.0227 2 0 WCM91_Z1_1 19 8464856 59083970 0.20120.9752 1.9774 1.9544 2 2 WCM91_Z1_1 2 41612 56603065 −0.1228 0.58831.9865 1.0204 2 1 WCM91_Z1_1 2 56611401 58468432 −1.264 −1.0017 NA NA NANA WCM91_Z1_1 2 60614577 240500560 −0.1229 0.5882 1.9974 1.0093 2 1WCM91_Z1_1 2 240504712 242946607 −0.4034 0.2373 1.9984 0.3592 2 0WCM91_Z1_1 20 68375 2517926 0.1827 0.9536 2.0207 1.8527 2 2 WCM91_Z1_120 2539274 3585650 −0.6148 −0.0399 1.951 −0.0055 2 0 WCM91_Z1_1 203605206 62904925 0.2062 0.9811 1.9739 1.9739 2 2 WCM91_Z1_1 21 982620748084253 −0.1426 0.5641 2.0039 0.953 2 1 WCM91_Z1_1 22 16287443 51219138−0.1652 0.5364 1.9498 0.9509 2 1 WCM91_Z1_1 3 239398 71161716 0.21960.9967 1.9954 1.9954 2 2 WCM91_Z1_1 3 71179670 73432800 −0.6262 −0.0552NA NA NA NA WCM91_Z1_1 3 73433185 197896720 0.217 0.9937 1.9983 1.9843 22 WCM91_Z1_1 4 59326 25235857 −0.1373 0.5706 1.9652 1.005 2 1 WCM91_Z1_14 25254012 57976479 −1.211 −0.9143 1.0636 −0.0024 1 0 WCM91_Z1_1 461788378 159165453 −0.1328 0.576 2.0106 0.9709 2 1 WCM91_Z1_1 4159174637 190426570 −1.2 −0.8964 1.0709 0.0036 1 0 WCM91_Z1_1 5 14066653467650 0.2119 0.9877 2.0016 1.9645 2 2 WCM91_Z1_1 5 53606277 54737696−0.6402 −0.0741 NA NA NA NA WCM91_Z1_1 5 54763765 58021848 −2.4768−5.2683 NA NA NA NA WCM91_Z1_1 5 58120955 150257586 −0.5666 0.02452.0502 −0.016 2 0 WCM91_Z1_1 5 150275227 150566946 0.6439 1.4811 NA NANA NA WCM91_Z1_1 5 150578592 180687776 0.1919 0.9644 1.9604 1.9421 2 2WCM91_Z1_1 6 203515 109563427 −0.1509 0.5539 1.9419 0.9943 2 1WCM91_Z1_1 6 109575770 170892772 0.2016 0.9757 1.9666 1.9666 2 2WCM91_Z1_1 7 193205 14758296 0.224 1.0019 2.026 1.9793 2 2 WCM91_Z1_1 714775720 22170598 −0.5154 0.092 2.1111 0.0207 2 0 WCM91_Z1_1 7 2217574396747098 0.2079 0.9831 1.9929 1.9605 2 2 WCM91_Z1_1 7 96810356 105148851−0.1228 0.5883 1.9664 1.0406 2 1 WCM91_Z1_1 7 105172804 111634284 0.20640.9813 NA NA NA NA WCM91_Z1_1 7 111638506 111982645 −0.6741 −0.1202 NANA NA NA WCM91_Z1_1 7 112090747 158937011 0.2102 0.9858 1.9804 1.9804 22 WCM91_Z1_1 8 190900 37689026 −0.5831 0.0025 2.0164 −0.0129 2 0WCM91_Z1_1 8 37690607 146279416 0.6365 1.4729 3.5841 1.9674 4 2WCM91_Z1_1 9 116832 131115438 0.0011 0.7383 1.9605 1.376 2 1 WCM91_Z1_19 131115784 136550376 −0.9933 −0.5749 1.3575 −0.0149 1 0 WCM91_Z1_1 9136555629 141111414 0.0181 0.7587 2.0038 1.38 2 1 WCM91_Z1_1 X 270014720081599 0.9618 1.8328 NA NA NA NA WCM91_Z1_1 X 20134945 57936542 0.74021.5885 NA NA NA NA WCM91_Z1_1 X 62898360 65486458 1.4266 2.3343 NA NA NANA WCM91_Z1_1 X 65819524 66943685 3.3069 4.2824 NA NA NA NA WCM91_Z1_1 X67268291 154509348 −0.6037 −0.0251 NA NA NA NA WCM9_X1_1 1 72145059042563 −0.0131 0.8658 2.6238 1.021 3 1 WCM9_X1_1 1 59042734 79357292−0.4094 −0.785 1.2246 −0.0639 1 0 WCM9_X1_1 1 79358827 249212366 −0.01010.8741 2.5271 1.1387 3 1 WCM9_X1_1 10 243934 135440117 −0.0196 0.84732.4425 1.1557 2 1 WCM9_X1_1 11 193127 123886681 −0.0051 0.8882 2.54231.1595 3 1 WCM9_X1_1 11 123887066 134856592 −0.1544 0.4222 2.5073 0.17273 0 WCM9_X1_1 12 148642 111072571 0.1822 1.3629 2.5897 2.5542 3 3WCM9_X1_1 12 111074280 115120975 −0.2067 0.2301 1.9867 0.3592 2 0WCM9_X1_1 12 115801948 133779951 0.0043 0.9146 2.2723 1.4978 2 1WCM9_X1_1 12 133780309 133810703 −0.0539 0.7469 NA NA NA NA WCM9_X1_1 1319600147 48833056 0.2849 1.5891 3.2185 2.7989 3 3 WCM9_X1_1 13 48835315115089411 −0.2093 0.22 2.3696 −0.0401 2 0 WCM9_X1_1 14 19377701 218408470.098 1.1611 2.7165 1.756 3 2 WCM9_X1_1 14 21851781 78398036 0.15321.2952 2.4541 2.4541 2 2 WCM9_X1_1 14 78399592 107283019  7.00E−040.9046 2.4201 1.3239 2 1 WCM9_X1_1 15 20170019 102514159 −0.0187 0.84992.441 1.1638 2 1 WCM9_X1_1 16 66930 18903638 0.0131 0.9389 2.5646 1.26953 1 WCM9_X1_1 16 18908268 90086249 0.1559 1.3016 2.5289 2.401 3 2WCM9_X1_1 16 90086471 90233294 −0.0086 0.8786 2.6736 1.0036 3 1WCM9_X1_1 17 131595 10555851 −0.2049 0.2371 2.4551 −0.0978 2 0 WCM9_X1_117 10558376 30981567 −0.0014 0.8987 2.5628 1.166 3 1 WCM9_X1_1 1730986163 34948538 −0.2208 0.1749 2.5212 −0.2634 3 0 WCM9_X1_1 1734951424 36552222 0.1723 1.3399 NA NA NA NA WCM9_X1_1 17 3670404538991032 −0.2308 0.1349 2.823 −0.627 3 −1  WCM9_X1_1 17 3899147639634674 0.0283 0.9802 NA NA NA NA WCM9_X1_1 17 39635231 46265278 0.24751.5089 2.9265 2.7655 3 3 WCM9_X1_1 17 46266848 49365936 0.042 1.0172.2386 1.8089 2 2 WCM9_X1_1 17 49371340 58711271 −0.1965 0.2692 2.571−0.1608 3 0 WCM9_X1_1 17 58725437 60837229 0.1193 1.2135 NA NA NA NAWCM9_X1_1 17 60879042 64225437 0.4313 1.8825 4.8621 2.5124 5 3 WCM9_X1_117 64299011 65103522 −0.141 0.4686 NA NA NA NA WCM9_X1_1 17 6510378481083507 −0.2073 0.228 2.4411 −0.0986 2 0 WCM9_X1_1 18 48224 580797−0.1594 0.4047 NA NA NA NA WCM9_X1_1 18 617996 29340380 −0.0031 0.8942.254 1.4627 2 1 WCM9_X1_1 18 29340529 46448256 −0.3787 −0.5889 1.32690.0028 1 0 WCM9_X1_1 18 46468946 67231807 −0.1966 0.2686 1.3048 1.1045 11 WCM9_X1_1 18 67266700 78005194 −0.3498 −0.4228 1.0244 0.4676 1 0WCM9_X1_1 19 281433 59083951 −0.0199 0.8463 2.5286 1.0672 3 1 WCM9_X1_12 41615 242946616 −0.0151 0.8601 2.4038 1.2266 2 1 WCM9_X1_1 20 6837562904848 0.1573 1.3047 2.5285 2.4122 3 2 WCM9_X1_1 21 9826207 48084210−0.2375 0.1077 1.1439 1.0111 1 1 WCM9_X1_1 22 17060362 40364102 −0.20240.2468 1.2501 1.1231 1 1 WCM9_X1_1 22 40365458 51159824 −0.0296 0.81842.4075 1.1194 2 1 WCM9_X1_1 22 51160242 51215157 −0.2172 0.1894 NA NA NANA WCM9_X1_1 3 239405 52437893 −0.147 0.448 2.74 −0.0118 3 0 WCM9_X1_1 352438553 54880461 −0.4438 −1.0355 0.7602 0.2155 1 0 WCM9_X1_1 3 5490562097499470 0.0298 0.9843 3.6562 0.3006 4 0 WCM9_X1_1 3 97503887 1218104670.1096 1.1899 3.7505 0.8121 4 1 WCM9_X1_1 3 121822524 141164413 0.34081.7048 3.3127 3.207 3 3 WCM9_X1_1 3 141164729 142561804 0.1723 1.33994.1363 0.9263 4 1 WCM9_X1_1 3 142562146 164059210 0.0121 0.9362 3.9706−0.1437 4 0 WCM9_X1_1 3 164697153 185826295 0.3327 1.6883 3.4002 3.04543 3 WCM9_X1_1 3 185867924 197896714 −0.0182 0.8513 3.427 0.1813 3 0WCM9_X1_1 4 59331 190396288 −0.2011 0.2517 2.4477 −0.0666 2 0 WCM9_X1_15 140636 180687814 −0.0091 0.877 2.2824 1.3907 2 1 WCM9_X1_1 6 20358325554247 −0.1641 0.388 2.3516 0.2655 2 0 WCM9_X1_1 6 25557017 84233628−0.0067 0.8839 2.3076 1.3832 2 1 WCM9_X1_1 6 84233831 151674270 −0.18520.3114 2.4753 0.0066 2 0 WCM9_X1_1 6 151674506 170156857 −0.0212 0.84272.2972 1.2895 2 1 WCM9_X1_1 6 170159096 170893454 −0.1009 0.6013 NA NANA NA WCM9_X1_1 7 193253 26192171 0.1248 1.227 2.3806 2.301 2 2WCM9_X1_1 7 26192678 158937142 −0.0096 0.8757 2.4827 1.187 2 1 WCM9_X1_18 190897 146279423 −0.0112 0.8711 2.6471 1.0112 3 1 WCM9_X1_1 9 1706624545256 −0.1616 0.3967 2.5618 0.0711 3 0 WCM9_X1_1 9 24545500 134312107−0.0174 0.8535 2.4151 1.1986 2 1 WCM9_X1_1 9 134314386 134393686 −0.13420.4917 NA NA NA NA WCM9_X1_1 9 134393862 141006877 0.1689 1.3319 2.64642.3883 3 2 WCM9_X1_1 9 141008931 141111414 −0.0345 0.8042 NA NA NA NAWCM9_X1_1 X 2707709 64744479 0.3486 1.7205 NA NA NA NA WCM9_X1_1 X64744852 75003338 0.7277 2.4039 NA NA NA NA WCM9_X1_1 X 75003567154509348 0.1223 1.2211 NA NA NA NA WCM9_Z3-1 1 762142 59364783 −0.3745−0.6037 0.673 0.6431 1 1 WCM9_Z3-1 1 59787350 77987517 −0.4113 −0.69821.1045 0.1282 1 0 WCM9_Z3-1 1 78024284 249212550 −0.1789 −0.1538 1.04320.7546 1 1 WCM9_Z3-1 10 243934 135381766 −0.0753 0.0569 1.0402 1.0402 11 WCM9_Z3-1 11 193144 134257738 −0.0527 0.1009 1.0828 1.0621 1 1WCM9_Z3-1 12 283817 133810703 −0.2954 −0.4122 0.762 0.741 1 1 WCM9_Z3-113 19601055 115089411 −0.3174 −0.4639 1.2443 0.2058 1 0 WCM9_Z3-1 1420201798 65453785 −0.0075 0.187 1.1384 1.1384 1 1 WCM9_Z3-1 14 6547102178028803 −0.4964 −0.9331 0.8544 0.1931 1 0 WCM9_Z3-1 14 78036835107283068 −0.0532 0.0998 1.0965 1.0468 1 1 WCM9_Z3-1 15 20170053102389740 −0.1163 −0.0246 0.993 0.9732 1 1 WCM9_Z3-1 16 97558 90160840−0.1476 −0.0886 0.9404 0.9404 1 1 WCM9_Z3-1 17 131595 81083455 −0.517−0.994 1.0128 −0.0086 1 0 WCM9_Z3-1 18 48202 78005214 −0.0696 0.0681.0544 1.0421 1 1 WCM9_Z3-1 19 281435 59083970 −0.3677 −0.5867 0.92070.411 1 0 WCM9_Z3-1 2 41620 179394802 −0.1042 −4.00E−04 1.1517 0.8478 11 WCM9_Z3-1 2 179395151 179635158 0.9601 1.6699 3.1819 3.1819 3 3WCM9_Z3-1 2 179635550 242946607 −0.0354 0.134 1.0973 1.0973 1 1WCM9_Z3-1 20 68375 62904932 −0.1522 −0.0981 1.1199 0.7485 1 1 WCM9_Z3-121 9826203 48084226 −0.244 −0.295 0.8278 0.8024 1 1 WCM9_Z3-1 2217060362 51214211 −0.5339 −1.045 0.6836 0.2857 1 0 WCM9_Z3-1 3 23944354930848 −0.4193 −0.7193 1.1619 0.0528 1 0 WCM9_Z3-1 3 54933874148877862 −0.0052 0.1913 1.1418 1.1418 1 1 WCM9_Z3-1 3 148880004151171249 −0.2709 −0.3556 1.4087 0.1544 1 0 WCM9_Z3-1 3 151171439196460733 −0.0814 0.0449 1.0621 1.0011 1 1 WCM9_Z3-1 3 196528821197762833 −0.333 −0.5013 NA NA NA NA WCM9_Z3-1 4 59405 190395617 −0.1563−0.1066 1.1467 0.7108 1 1 WCM9_Z3-1 5 140532 180687769 −0.0243 0.15531.1137 1.1137 1 1 WCM9_Z3-1 6 203516 87967574 −0.0025 0.1964 1.14581.1458 1 1 WCM9_Z3-1 6 87967696 151917713 −0.4131 −0.7031 1.1679 0.06061 0 WCM9_Z3-1 6 151936677 170893438 −0.1731 −0.1416 0.9198 0.8931 1 1WCM9_Z3-1 7 193205 158937158 −0.076 0.0554 1.0453 1.033 1 1 WCM9_Z3-1 8190897 444591 0.3895 0.8606 NA NA NA NA WCM9_Z3-1 8 494742 47842983−0.1523 −0.0982 1.7059 0.1625 2 0 WCM9_Z3-1 8 48102450 146279507 0.43470.9301 1.9054 1.9054 2 2 WCM9_Z3-1 9 214625 21409282 −0.3713 −0.59571.0871 0.2363 1 0 WCM9_Z3-1 9 21409551 140995594 −0.2192 −0.2404 0.84650.8465 1 1 WCM9_Z3-1 9 141000211 141071248 −1.5361 NA NA NA NA NAWCM9_Z3-1 X 2707688 154509348 −0.1724 −0.1401 NA NA NA NA

(v) Tumor Ploidy and Tumor Content Assessment

To assess tumor ploidy and tumor content (estimation of cfDNA tumorfraction, ctDNA) from plasma DNA samples, an extended version of CLONETwas used (Prandi and Demichelis (2019) Curr Protoc Bioinformatics67:e81), a tool developed to deal with highly heterogeneous tissuesamples. It now embeds a refined mathematical approach for local tumorcontent estimation (TC) (Prandi and Demichelis (2019) Curr ProtocBioinformatics 67:e81) to further increase the performance incomputation time and in the ability to detect somatic aberrations in lowTC samples. Specifically, a new method for the calculation of CLONET βvalues (i.e., the percentage of reads from cells harboring two alleles)was implemented and used in this work. For each segment S, previouslyidentified, the corresponding β value was compute with the followingformula:

β=max{i|W(d>D _(i))}+(max{i|W(d<D _(i))}−min{i|W(d>D _(i))})*P

where

P=(median(d)−min(d)/(max(d)−min(d))

and W(d>D_(i)) is the Mann-Whitney statistics (using significance cutoffat 1%) comparing the mirrored AF distribution distribution of allinformative SNPs in segment S (i.e., SNPs with heterozygous genotype ingermline patient's sample) and the reference distribution D_(i)simulating a mono-allelic deletion with β=i(were i∈[0,1]) and AF noiseestimated from the germline patient's samples at SNPs positions. Theextended CLONET pipeline was applied to estimate TC and ploidy of allcfDNA and tumor tissue samples. CLONET analysis estimated tumor contentfor 55 out of 69 plasma samples (80% of the total): 30 samples withtumor content >=20% (43% of the total), 43 samples with tumorcontent >=10% (62% of the total) and 12 samples with tumor content <10%.Manual inspection of the somatic copy number profiles of the remaining15 samples indicate low or absent tumor signal. Ploidy estimates wereavailable for 68 samples with 12 samples having a ploidy >=2.5. Fortumor tissue samples, CLONET analysis estimated tumor content for 90 outof 98 samples: 85 samples with tumor content >=20% (87% of the total),87 samples with tumor content >=10% and 1 samples with tumor content<10%. Ploidy estimates were available for 96 samples with 34 sampleshaving a ploidy >=2.5. CLONET allele-specific somatic copy numberprofiles were computed for all plasma and tissue samples at gene-levelresolution, using a gene model consisting of 19,027 genes (Table 3).

(vi) Detection of Somatic Single Nucleotide Variants

To identify and characterize somatic single-nucleotide variants (SNVs)in WES captured regions, MuTect (Cibulskis et al. (2013) Nat Biotechnol31:213-219) was run on BAM files and read duplicates were removed usingPicard (available on the World Wide Web atbroadinstitute.github.io/picard). Putative somatic SNVs were nominatedas genomic positions called by MuTect and having in the plasma/tumorsample a depth of

alternative base, and having in the matched normal sample an allelicfraction <0.01. Oncotator (Ramos et al. (2015) Hum Mutat 36:E2423-2429)was finally used to annotate retained SNVs with variant- andgene-centric information relevant to cancer. Complete annotated list ofcalled missense SNVs is available in Table 4.

TABLE 4 Non-Synonymous SNVs Data Allelic Allelic Coverage fractionCoverage Fraction in in in in tumor/ tumor/ Chr Position Ref. Alt. HugoProtein normal control plasma plasma (hg19) (hg19) base base SymbolChange sample sample sample sample Sample Type 1 183093931 C A LAMC1p.T856N 0 36 0.150685 73 WCM0 Plasma 1 241753378 C T KMO p.A388V 0 380.282353 85 WCM0 Plasma 13 48923137 G T RB1 p.W195C 0 42 0.413462 104WCM0 Plasma 14 38061334 G A FOXA1 p.R219C 0 31 0.223881 67 WCM0 Plasma18 50918073 C A DCC p.T835N 0 34 0.171429 70 WCM0 Plasma 19 16472591 G AEPS15L1 p.S862F 0 44 0.205882 136 WCM0 Plasma 3 186281967 C T TBCCD1p.R51H 0 38 0.35 100 WCM0 Plasma 5 121413104 G T LOX p.P193T 0 470.097345 113 WCM0 Plasma 6 136681140 C G MAP7 p.R611S 0 37 0.087912 91WCM0 Plasma 9 131860587 C G CRAT p.K423N 0 36 0.190476 63 WCM0 Plasma 1145562588 G C ANKRD35 p.G759A 0 215 0.100629 159 WCM0_LM1 Tissue 115528985 A T UBQLN3 p.L602I 0 243 0.231707 164 WCM0_LM1 Tissue 1174904293 G A SLCO2B1 p.R369H 0 276 0.502164 231 WCM0_LM1 Tissue 1183093931 C A LAMC1 p.T856N 0 317 0.514124 354 WCM0_LM1 Tissue 1194532860 C A AMOTL1 p.D168E 0 542 0.241791 670 WCM0_LM1 Tissue 12108685719 C G CMKLR1 p.D341H 0 304 0.563636 275 WCM0_LM1 Tissue 1241753378 C T KMO p.A388V 0 232 0.411552 277 WCM0_LM1 Tissue 12 6495257C G LTBR p.H166Q 0 199 0.285714 63 WCM0_LM1 Tissue 13 48923137 G T RB1p.W195C 0 266 0.875817 153 WCM0_LM1 Tissue 14 38061334 G A FOXA1 p.R219C0 560 0.427914 652 WCM0_LM1 Tissue 14 93117957 A T RIN3 p.Q188L 0 2710.261062 226 WCM0_LM1 Tissue 15 78893807 C A CHRNA3 p.E393* 0 5980.463196 557 WCM0_LM1 Tissue 17 10209870 T C MYH13 p.E1791G 0 1530.068323 161 WCM0_LM1 Tissue 17 28769407 A G CPD p.E771G 0 152 0.675373268 WCM0_LM1 Tissue 1 75693493 A C SLC44A5 p.S301R 0 505 0.544029 829WCM0_LM1 Tissue 17 76130640 A T TMC8 p.K328* 0.008696 230 0.49 200WCM0_LM1 Tissue 17 80887372 C T TBCD p.S996L 0 416 0.207675 443 WCM0_LM1Tissue 18 50918073 C A DCC p.T835N 0 761 0.423002 513 WCM0_LM1 Tissue 1911617019 G A ECSIT p.Q426* 0 103 0.371179 229 WCM0_LM1 Tissue 1916040379 C G CYP4F11 p.L77F 0 344 0.307818 614 WCM0_LM1 Tissue 1916472591 G A EPS15L1 p.S862F 0 90 0.451977 177 WCM0_LM1 Tissue 1919313184 G A NR2C2AP p.H87Y 0 318 0.272861 678 WCM0_LM1 Tissue 1922847655 G A ZNF492 p.C395Y 0 44 0.122222 90 WCM0_LM1 Tissue 1 9305367 AC H6PD p.E125A 0 604 0.311178 331 WCM0_LM1 Tissue 19 40380382 C A FCGBPp.G3645C 0 33 0.090909 33 WCM0_LM1 Tissue 19 48643373 G C LIG1 p.N314K 077 0.1375 80 WCM0_LM1 Tissue 19 50029305 C G FCGRT p.L343V 0 9760.054455 606 WCM0_LM1 Tissue 19 51189522 T A SHANK1 p.H850L 0 4530.287781 622 WCM0_LM1 Tissue 19 56370147 T G NLRP4 p.F463C 0 5470.121437 807 WCM0_LM1 Tissue 19 5843818 G T FUT3 p.Q345K 0 37 0.0625 48WCM0_LM1 Tissue 20 47865195 G A ZNFX1 p.R1456C 0 493 0.514477 449WCM0_LM1 Tissue 20 60882854 G A ADRM1 p.V276I 0 474 0.482684 462WCM0_LM1 Tissue 22 21153533 G A PI4KA p.R560* 0 102 0.097561 41 WCM0_LM1Tissue 3 186281967 C T TBCCD1 p.R51H 0 368 0.486216 399 WCM0_LM1 Tissue4 134073066 C T PCDH10 p.P591S 0 428 0.101504 532 WCM0_LM1 Tissue 5121413104 G T LOX p.P193T 0 533 0.232782 726 WCM0_LM1 Tissue 6 108492701G A NR2E1 p.R22H 0 182 0.431373 153 WCM0_LM1 Tissue 6 110567235 A GMETTL24 p.S339P 0.001751 571 0.506156 731 WCM0_LM1 Tissue 6 136681140 CG MAP7 p.R611S 0 311 0.216912 272 WCM0_LM1 Tissue 6 24716433 C G C6orf62p.E83D 0 231 0.193676 253 WCM0_LM1 Tissue 7 141619105 G T OR9A4 p.V144L0 493 0.48595 605 WCM0_LM1 Tissue 7 142574254 G C TRPV6 p.D223E 0 3500.152542 413 WCM0_LM1 Tissue 8 22165564 G A PIWIL2 p.R555H 0 74 0.91525459 WCM0_LM1 Tissue 9 131860587 C G CRAT p.K423N 0 365 0.247387 287WCM0_LM1 Tissue 9 135139691 A G SETX p.S2657P 0.001193 838 0.056805 845WCM0_LM1 Tissue 9 139902948 C A ABCA2 p.E2398* 0 251 0.25 192 WCM0_LM1Tissue X 135291473 C T FHL1 p.R254C 0 31 0.979592 49 WCM0_LM1 Tissue X96369830 C T DIAPH2 p.L819F 0 282 0.465046 329 WCM0_LM1 Tissue 11119170354 G A CBL p.E862K 0 631 0.083086 674 WCM0_LM2 Tissue 11 26725464C A SLC5A12 p.A186S 0 88 0.067568 74 WCM0_LM2 Tissue 1 145562588 G CANKRD35 p.G759A 0 215 0.156463 147 WCM0_LM2 Tissue 11 4615558 G T OR52I1p.S97I 0 81 0.071429 42 WCM0_LM2 Tissue 11 6024189 C A OR56A4 p.V64F 0176 0.050505 99 WCM0_LM2 Tissue 11 74904293 G A SLCO2B1 p.R369H 0 2760.526923 260 WCM0_LM2 Tissue 1 183093931 C A LAMC1 p.T856N 0 3170.334694 245 WCM0_LM2 Tissue 11 94532860 C A AMOTL1 p.D168E 0 5420.239598 697 WCM0_LM2 Tissue 12 108685719 C G CMKLR1 p.D341H 0 3040.508929 224 WCM0_LM2 Tissue 1 241753378 C T KMO p.A388V 0 232 0.336788193 WCM0_LM2 Tissue 13 48923137 G T RB1 p.W195C 0 266 0.9375 112WCM0_LM2 Tissue 14 38061334 G A FOXA1 p.R219C 0 560 0.503949 633WCM0_LM2 Tissue 14 93117957 A T RIN3 p.Q188L 0 271 0.252033 246 WCM0_LM2Tissue 15 78893807 C A CHRNA3 p.E393* 0 598 0.486957 575 WCM0_LM2 Tissue16 29755841 C A C16orf54 p.E144D 0 98 0.067797 59 WCM0_LM2 Tissue 1668056205 C T DDX28 p.D301N 0 663 0.052326 344 WCM0_LM2 Tissue 1728769407 A G CPD p.E771G 0 152 0.692661 218 WCM0_LM2 Tissue 1 75693493 AC SLC44A5 p.S301R 0 505 0.496656 598 WCM0_LM2 Tissue 17 57153068 C ATRIM37 p.K208N 0 116 0.051948 77 WCM0_LM2 Tissue 17 76130640 A T TMC8p.K328* 0.008696 230 0.471264 174 WCM0_LM2 Tissue 17 80887372 C T TBCDp.S996L 0 416 0.237179 468 WCM0_LM2 Tissue 18 50918073 C A DCC p.T835N 0761 0.424036 441 WCM0_LM2 Tissue 19 11617019 G A ECSIT p.Q426* 0 1030.252747 182 WCM0_LM2 Tissue 19 16040379 C G CYP4F11 p.L77F 0 3440.283582 536 WCM0_LM2 Tissue 19 16472591 G A EPS15L1 p.S862F 0 900.341346 208 WCM0_LM2 Tissue 19 19313184 G A NR2C2AP p.H87Y 0 3180.225962 624 WCM0_LM2 Tissue 19 22847655 G A ZNF492 p.C395Y 0 440.255319 47 WCM0_LM2 Tissue 1 9305367 A C H6PD p.E125A 0 604 0.267956362 WCM0_LM2 Tissue 19 48643373 G C LIG1 p.N314K 0 77 0.146667 75WCM0_LM2 Tissue 19 51189522 T A SHANK1 p.H850L 0 453 0.342908 557WCM0_LM2 Tissue 19 56370147 T G NLRP4 p.F463C 0 547 0.178344 628WCM0_LM2 Tissue 19 5843871 C T FUT3 p.R327Q 0 39 0.069767 43 WCM0_LM2Tissue 20 47865195 G A ZNFX1 p.R1456C 0 493 0.488281 512 WCM0_LM2 Tissue20 60882854 G A ADRM1 p.V276I 0 474 0.505929 506 WCM0_LM2 Tissue 2131415089 G T POTEJ p.R919L 0 91 0.054348 92 WCM0_LM2 Tissue 3 186281967C T TBCCD1 p.R51H 0 368 0.428571 427 WCM0_LM2 Tissue 5 121413104 G T LOXp.P193T 0 533 0.250382 655 WCM0_LM2 Tissue 6 108492701 G A NR2E1 p.R22H0 182 0.536585 164 WCM0_LM2 Tissue 6 110567235 A G METTL24 p.S339P0.001751 571 0.484892 695 WCM0_LM2 Tissue 6 136681140 C G MAP7 p.R611S 0311 0.291304 230 WCM0_LM2 Tissue 6 24716433 C G C6orf62 p.E83D 0 2310.263374 243 WCM0_LM2 Tissue 6 32012994 C G TNXB p.M3572I 0 44 0.09756141 WCM0_LM2 Tissue 7 141619105 G T OR9A4 p.V144L 0 493 0.484603 617WCM0_LM2 Tissue 7 150674998 G A KCNH2 p.P2S 0 49 0.08 50 WCM0_LM2 Tissue7 4876021 G C RADIL p.L251V 0 43 0.071429 42 WCM0_LM2 Tissue 8 22165564G A PIWIL2 p.R555H 0 74 1 38 WCM0_LM2 Tissue 9 131860587 C G CRATp.K423N 0 365 0.212963 324 WCM0_LM2 Tissue 9 139902948 C A ABCA2p.E2398* 0 251 0.220149 268 WCM0_LM2 Tissue X 135291473 C T FHL1 p.R254C0 31 0.96875 64 WCM0_LM2 Tissue X 96369830 C T DIAPH2 p.L819F 0 2820.474903 259 WCM0_LM2 Tissue 10 31134360 C T ZNF438 p.E673K 0 9650.43131 626 WCMO_PM1 Tissue 10 89118177 C A NUTM2D p.A52D 0 55 0.0638347 WCMO_PM1 Tissue 11 55890099 C A OR8H3 p.A84E 0 76 0.058824 51WCMO_PM1 Tissue 1 156012692 C A UBQLN4 p.S380I 0 142 0.05618 89 WCMO_PM1Tissue 11 74904293 G A SLCO2B1 p.R369H 0 276 0.430303 330 WCMO_PM1Tissue 1 241753378 C T KMO p.A388V 0 232 0.422311 251 WCMO_PM1 Tissue 1348923137 G T RB1 p.W195C 0 266 0.944444 126 WCMO_PM1 Tissue 14 38061334G A FOXA1 p.R219C 0 560 0.623639 643 WCMO_PM1 Tissue 1 46105974 C AGPBP1L1 p.G218* 0 253 0.20649 339 WCMO_PM1 Tissue 15 78893807 C A CHRNA3p.E393* 0 598 0.333333 456 WCMO_PM1 Tissue 17 10558268 G C MYH3 p.C38W 01106 0.20547 1426 WCMO_PM1 Tissue 17 10558269 C T MYH3 p.C38Y 0 10950.20736 1413 WCMO_PM1 Tissue 17 28769407 A G CPD p.E771G 0 152 0.61674227 WCMO_PM1 Tissue 1 75693493 A C SLC44A5 p.S301R 0 505 0.46849 841WCMO_PM1 Tissue 17 76130640 A T TMC8 p.K328* 0.008696 230 0.477387 199WCMO_PM1 Tissue 1 92801974 C G RPAP2 p.R537G 0 163 0.455556 90 WCM0_PM1Tissue 19 51189522 T A SHANK1 p.H850L 0 453 0.44086 465 WCM0_PM1 Tissue20 47865195 G A ZNFX1 p.R1456C 0 493 0.539286 560 WCM0_PM1 Tissue 2060882854 G A ADRM1 p.V276I 0 474 0.483146 623 WCM0_PM1 Tissue 2145993661 G T KRTAP10-4 p.S9I 0 74 0.072727 55 WCM0_PM1 Tissue 3186281967 C T TBCCD1 p.R51H 0 368 0.458774 473 WCM0_PM1 Tissue 358121847 C G FLNB p.R1605G 0 460 0.083004 253 WCM0_PM1 Tissue 6108492701 G A NR2E1 p.R22H 0 182 0.440171 234 WCM0_PM1 Tissue 6110567235 A G METTL24 p.S339P 0.001751 571 0.469697 792 WCM0_PM1 Tissue6 136681140 C G MAP7 p.R611S 0 311 0.206704 358 WCM0_PM1 Tissue 7141619105 G T OR9A4 p.V144L 0 493 0.491329 692 WCM0_PM1 Tissue 8121823950 G C SNTB1 p.A45G 0 113 0.25641 117 WCM0_PM1 Tissue 8 121823951C T SNTB1 p.A45T 0.008929 112 0.25641 117 WCM0_PM1 Tissue 8 22165564 G APIWIL2 p.R555H 0 74 0.934426 61 WCM0_PM1 Tissue X 135291473 C T FHL1p.R254C 0 31 0.964286 56 WCM0_PM1 Tissue 10 31134360 C T ZNF438 p.E673K0 965 0.503425 584 WCM0_PM2 Tissue 11 64119018 G T CCDC88B p.S1010I 0 810.066667 45 WCM0_PM2 Tissue 11 74904293 G A SLCO2B1 p.R369H 0 2760.53125 224 WCM0_PM2 Tissue 1 241753378 C T KMO p.A388V 0 232 0.495763236 WCM0_PM2 Tissue 13 48923137 G T RB1 p.W195C 0 266 0.96988 166WCM0_PM2 Tissue 1 36642105 G A MAP7D1 p.G386S 0.008333 120 0.058252 103WCM0_PM2 Tissue 14 38061334 G A FOXA1 p.R219C 0 560 0.705769 520WCM0_PM2 Tissue 15 78893807 C A CHRNA3 p.E393* 0 598 0.291284 436WCM0_PM2 Tissue 17 10558268 G C MYH3 p.C38W 0 1106 0.220508 1102WCM0_PM2 Tissue 17 10558269 C T MYH3 p.C38Y 0 1095 0.224565 1091WCM0_PM2 Tissue 17 28769407 A G CPD p.E771G 0 152 0.618257 241 WCM0_PM2Tissue 17 39383010 C A KRTAP9-2 p.T35K 0 57 0.078947 38 WCM0_PM2 Tissue17 39389012 G A KRTAP9-3 p.G87R 0 71 0.081967 61 WCM0_PM2 Tissue 175693493 A C SLC44A5 p.S301R 0 505 0.489388 801 WCM0_PM2 Tissue 1757941135 C A TUBD1 p.Q383H 0 185 0.064103 78 WCM0_PM2 Tissue 17 76130640A T TMC8 p.K328* 0.008696 230 0.469072 194 WCM0_PM2 Tissue 18 29340528 GT SLC25A52 p.H33N 0 36 0.068182 44 WCM0_PM2 Tissue 1 92801974 C G RPAP2p.R537G 0 163 0.44 100 WCM0_PM2 Tissue 19 41383141 C T CYP2A7 p.R372H 0303 0.126761 355 WCM0_PM2 Tissue 19 51189522 T A SHANK1 p.H850L 0 4530.421659 434 WCM0_PM2 Tissue 20 47865195 G A ZNFX1 p.R1456C 0 4930.474041 443 WCM0_PM2 Tissue 20 60882854 G A ADRM1 p.V276I 0 4740.469828 464 WCM0_PM2 Tissue 3 186281967 C T TBCCD1 p.R51H 0 3680.498818 423 WCM0_PM2 Tissue 6 108492701 G A NR2E1 p.R22H 0 182 0.407609184 WCM0_PM2 Tissue 6 110567235 A G METTL24 p.S339P 0.001751 5710.491803 671 WCM0_PM2 Tissue 6 136681140 C G MAP7 p.R611S 0 311 0.266106357 WCM0_PM2 Tissue 7 141619105 G T OR9A4 p.V144L 0 493 0.463636 660WCM0_PM2 Tissue 7 38433732 G A AMPH p.A494V 0 628 0.079893 751 WCM0_PM2Tissue 8 22165564 G A PIWIL2 p.R555H 0 74 0.970588 34 WCM0_PM2 Tissue 842940369 T A FNTA p.S362T 0 94 0.082645 121 WCM0_PM2 Tissue X 135291473C T FHL1 p.R254C 0 31 0.974359 39 WCM0_PM2 Tissue 10 31134360 C T ZNF438p.E673K 0 965 0.279528 762 WCM0_T24 Tissue 11 105923958 C T KBTBD3p.W486* 0 313 0.052036 442 WCM0_T24 Tissue 11 74904293 G A SLCO2B1p.R369H 0 276 0.523466 277 WCM0_T24 Tissue 12 110290404 C A GLTP p.E196*0 67 0.09375 32 WCM0_T24 Tissue 1 241753378 C T KMO p.A388V 0 2320.434164 281 WCM0_T24 Tissue 13 48923137 G T RB1 p.W195C 0 266 0.84492187 WCM0_T24 Tissue 14 38061334 G A FOXA1 p.R219C 0 560 0.545455 649WCM0_T24 Tissue 15 101605608 C A LRRK1 p.P1656T 0 432 0.079186 442WCM0_T24 Tissue 15 78893807 C A CHRNA3 p.E393* 0 598 0.344231 520WCM0_T24 Tissue 17 10558268 G C MYH3 p.C38W 0 1106 0.154589 1242WCM0_T24 Tissue 17 10558269 C T MYH3 p.C38Y 0 1095 0.15154 1234 WCM0_T24Tissue 17 11515065 C G DNAH9 p.A291G 0 120 0.074074 135 WCM0_T24 Tissue17 28769407 A G CPD p.E771G 0 152 0.600823 243 WCM0_T24 Tissue 1739778650 T C KRT17 p.N210S 0 52 0.06383 47 WCM0_T24 Tissue 1 75693493 AC SLC44A5 p.S301R 0 505 0.45814 860 WCM0_T24 Tissue 17 76130640 A T TMC8p.K328* 0.008696 230 0.478448 232 WCM0_T24 Tissue 1 92801974 C G RPAP2p.R537G 0 163 0.21875 96 WCM0_T24 Tissue 19 51189522 T A SHANK1 p.H850L0 453 0.380457 481 WCM0_T24 Tissue 20 42969923 G A R3HDML p.V117M 0 5040.083164 493 WCM0_T24 Tissue 20 47865195 G A ZNFX1 p.R1456C 0 4930.489362 517 WCM0_T24 Tissue 20 60882854 G A ADRM1 p.V276I 0 4740.474766 535 WCM0_T24 Tissue 2 103125390 C T SLC9A4 p.R496C 0 1220.12987 154 WCM0_T24 Tissue 2 128471433 T A WDR33 p.D1011V 0 7110.231183 372 WCM0_T24 Tissue 21 46117138 C A KRTAP10-12 p.L8M 0 590.055556 54 WCM0_T24 Tissue 3 186281967 C T TBCCD1 p.R51H 0 368 0.39759415 WCM0_T24 Tissue 3 23960890 C A RPL15 p.S171R 0 86 0.056604 53WCM0_T24 Tissue 3 50338477 G A HYAL1 p.A311V 0 119 0.055556 54 WCM0_T24Tissue 3 52817058 C T ITIH1 p.S339L 0 461 0.12 350 WCM0_T24 Tissue 6108492701 G A NR2E1 p.R22H 0 182 0.432692 208 WCM0_T24 Tissue 6110567235 A G METTL24 p.S339P 0.001751 571 0.485577 832 WCM0_T24 Tissue6 136681140 C G MAP7 p.R611S 0 311 0.22963 405 WCM0_T24 Tissue 6143486255 G A AIG1 p.D112N 0 296 0.054054 407 WCM0_T24 Tissue 6 34499489G A PACSIN1 p.D384N 0 247 0.099631 271 WCM0_T24 Tissue 7 141619105 G TOR9A4 p.V144L 0 493 0.472477 654 WCM0_T24 Tissue 8 22165564 G A PIWIL2p.R555H 0 74 0.88 50 WCM0_T24 Tissue 9 73027843 G A KLF9 p.P146L 0 2830.056522 230 WCM0_T24 Tissue X 135291473 C T FHL1 p.R254C 0 31 0.88372143 WCM0_T24 Tissue 10 23257326 G T ARMC3 p.G275V 0 161 0.338983 59WCM0_T5 Tissue 10 92616897 T A HTR7 p.I178F 0 367 0.163934 244 WCM0_T5Tissue 1 117122376 T C IGSF3 p.Y991C 0 692 0.133772 456 WCM0_T5 Tissue11 74904293 G A SLCO2B1 p.R369H 0 276 0.439331 239 WCM0_T5 Tissue 1220863884 C T C1orf115 p.A47V 0 85 0.196078 51 WCM0_T5 Tissue 1241753378 C T KMO p.A388V 0 232 0.412451 257 WCM0_T5 Tissue 13 48923137G T RB1 p.W195C 0 266 0.948718 156 WCM0_T5 Tissue 14 24644791 G T REC8p.E168* 0.001883 531 0.227273 1386 WCM0_T5 Tissue 14 38061334 G A FOXA1p.R219C 0 560 0.601887 530 WCM0_T5 Tissue 15 78893807 C A CHRNA3 p.E393*0 598 0.487319 552 WCM0_T5 Tissue 16 65005535 C G CDH11 p.S530T 0 3080.488987 227 WCM0_T5 Tissue 16 681269 C G WFIKKN1 p.P6A 0 220 0.06666775 WCM0_T5 Tissue 17 18566133 G T ZNF286B p.S229* 0 36 0.085714 35WCM0_T5 Tissue 17 28769407 A G CPD p.E771G 0 152 0.65 260 WCM0_T5 Tissue1 75693493 A C SLC44A5 p.S301R 0 505 0.492976 783 WCM0_T5 Tissue 1776130640 A T TMC8 p.K328* 0.008696 230 0.49162 179 WCM0_T5 Tissue 1951189522 T A SHANK1 p.H850L 0 453 0.419565 460 WCM0_T5 Tissue 2047865195 G A ZNFX1 p.R1456C 0 493 0.533835 399 WCM0_T5 Tissue 2060882854 G A ADRM1 p.V276I 0 474 0.521415 537 WCM0_T5 Tissue 2 110372320A C SOWAHC p.E85A 0 215 0.08642 162 WCM0_T5 Tissue 3 186281967 C TTBCCD1 p.R51H 0 368 0.414286 350 WCM0_T5 Tissue 4 160268015 C A RAPGEF2p.Q1032K 0 470 0.116114 422 WCM0_T5 Tissue 4 57367953 A C SRP72 p.K648Q0 195 0.097701 174 WCM0_T5 Tissue 5 136973004 C A KLHL3 p.V434L 0 1130.168919 148 WCM0_T5 Tissue 5 148427526 T A SH3TC2 p.S60C 0 72 0.132743113 WCM0_T5 Tissue 5 21760693 G T CDH12 p.P536Q 0 159 0.164894 188WCM0_T5 Tissue 5 40945369 A G C7 p.T213A 0 342 0.1125 400 WCM0_T5 Tissue6 108492701 G A NR2E1 p.R22H 0 182 0.648438 128 WCM0_T5 Tissue 6110567235 A G METTL24 p.S339P 0.001751 571 0.309122 592 WCM0_T5 Tissue 7141619105 G T OR9A4 p.V144L 0 493 0.519947 752 WCM0_T5 Tissue 8 22165564G A PIWIL2 p.R555H 0 74 0.979592 49 WCM0_T5 Tissue X 117577634 C G WDR44p.F832L 0 99 0.050505 99 WCM0_T5 Tissue X 135291473 C T FHL1 p.R254C 031 0.970588 34 WCM0_T5 Tissue X 26157715 G C MAGEB18 p.G205R 0 1060.180451 133 WCM0_T5 Tissue X 37026700 C T FAM47C p.R73C 0 66 0.48101379 WCM0_T5 Tissue 10 47669242 C T ANTXRL p.T247M 0 40 0.135593 59 WCM1Plasma 10 5139715 T A AKR1C3 p.Y114* 0 64 0.104651 86 WCM1 Plasma 112008048 T A PLOD1 p.L31H 0 59 0.267442 86 WCM1 Plasma 13 58208319 G TPCDH17 p.A547S 0 41 0.209302 43 WCM1 Plasma 15 28412883 C A HERC2p.D3502Y 0 54 0.177215 79 WCM1 Plasma 15 93563245 G T CHD2 p.R1637L 0 580.0625 64 WCM1 Plasma 16 58557296 C A CNOT1 p.A2299S 0 65 0.073171 82WCM1 Plasma 1 70728464 T C ANKRD13C p.D521G 0 33 0.061538 65 WCM1 Plasma17 19318461 G A RNF112 p.A413T 0 45 0.122449 49 WCM1 Plasma 17 72588241C T C17orf77 p.A19V 0 32 0.113924 79 WCM1 Plasma 18 28923489 A C DSG1p.E588D 0 70 0.219298 114 WCM1 Plasma 20 36625323 G T TTI1 p.D942E 0 490.059701 67 WCM1 Plasma 2 187523882 C T ITGAV p.P613S 0 55 0.223881 67WCM1 Plasma 4 164066996 T G NAF1 p.N219H 0 89 0.163934 122 WCM1 Plasma 455152038 G A PDGFRA p.V824I 0 56 0.239437 71 WCM1 Plasma 4 57244443 G TAASDH p.A180E 0 55 0.112903 62 WCM1 Plasma 5 5486894 C T KIAA0947p.S2194L 0 78 0.201835 109 WCM1 Plasma 7 117359625 T C CTTNBP2 p.D1526G0 43 0.129412 85 WCM1 Plasma 7 128409148 A G CALU p.D292G 0 55 0.15384678 WCM1 Plasma 8 125115401 A T FER1L6 p.N1714Y 0 60 0.136842 95 WCM1Plasma 8 95142932 G A CDH17 p.R774W 0 60 0.233645 107 WCM1 Plasma 914155884 C T NFIB p.E209K 0 69 0.229167 96 WCM1 Plasma X 144904175 T CSLITRK2 p.Y78H 0 43 0.202532 79 WCM1 Plasma 15 43748441 A C TP53BP1p.S784A 0 35 0.055556 72 WCM10 Plasma 16 58608985 G T CNOT1 p.L585I 0 670.056338 71 WCM10 Plasma 10 102782018 C A PDZD7 p.G223C 0 237 0.284916179 WCM10_Z1-1 Tissue 10 105128125 G A TAF5 p.V127M 0 88 0.092105 76WCM10_Z1-1 Tissue 10 105194032 C T PDCD11 p.R1198W 0 151 0.354839 124WCM10_Z1-1 Tissue 10 105207219 G A CALHM2 p.A221V 0 100 0.253165 79WCM10_Z1-1 Tissue 10 105331300 G A NEURL p.G124S 0 141 0.318182 132WCM10_Z1-1 Tissue 10 105831807 G A COL17A1 p.A149V 0 308 0.326923 312WCM10_Z1-1 Tissue 10 105889913 G A WDR96 p.A1661V 0 178 0.058824 170WCM10_Z1-1 Tissue 10 115612923 C T DCLRE1A p.E7K 0 79 0.314286 105WCM10_Z1-1 Tissue 10 118443350 C T HSPA12A p.V263I 0 81 0.30137 73WCM10_Z1-1 Tissue 10 12162822 G A DHTKD1 p.A899T 0 108 0.324324 74WCM10_Z1-1 Tissue 10 124753459 C T IKZF5 p.C366Y 0 104 0.059406 101WCM10_Z1-1 Tissue 10 129902969 G A MKI67 p.R2379* 0 538 0.336163 589WCM10_Z1-1 Tissue 10 129906317 T C MKI67 p.T1263A 0 418 0.356968 409WCM10_Z1-1 Tissue 10 131640410 C T EBF3 p.V448M 0 124 0.37069 116WCM10_Z1-1 Tissue 10 17891729 A G MRC1L1 p.I404V 0 94 0.758242 91WCM10_Z1-1 Tissue 10 23633673 A G C10orf67 p.Y12H 0 72 0.254545 55WCM10_Z1-1 Tissue 10 30317629 G A KIAA1462 p.P483L 0 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p.R706W 0 520.431034 58 WCM10_Z1-1 Tissue X 153196242 G A NAA10 p.R149W 0 390.594595 37 WCM10_Z1-1 Tissue X 153543623 C A TKTL1 p.S322Y 0 780.063291 79 WCM10_Z1-1 Tissue X 24227134 C A ZFX p.P404H 0 81 0.10256478 WCM10_Z1-1 Tissue X 37586937 G A XK p.R186H 0 76 0.717949 78WCM10_Z1-1 Tissue X 48839662 C T GRIPAP1 p.R488H 0 112 0.080808 99WCM10_Z1-1 Tissue X 49035644 C T PRICKLE3 p.V174M 0 81 0.629032 62WCM10_Z1-1 Tissue X 53970674 G A PHF8 p.R884C 0 104 0.681159 138WCM10_Z1-1 Tissue X 69478490 G A P2RY4 p.R329C 0 114 0.65625 96WCM10_Z1-1 Tissue X 70643034 C T TAF1 p.A1506V 0 77 0.616667 60WCM10_Z1-1 Tissue X 75649389 G A MAGEE1 p.V356I 0 157 0.694118 170WCM10_Z1-1 Tissue 11 19170770 G T ZDHHC13 p.Q137H 0 39 0.357143 98WCM119 Plasma 1 232568026 G A SIPA1L2 p.P1408L 0 50 0.255319 94 WCM119Plasma 12 75601178 C G KCNC2 p.A196P 0 33 0.337662 77 WCM119 Plasma 1717699855 G A RAI1 p.R1198K 0 41 0.096774 62 WCM119 Plasma 17 38510644 GA RARA p.A300T 0 37 0.4 55 WCM119 Plasma 17 60040181 G C MED13 p.L1666V0 47 0.211765 85 WCM119 Plasma 18 77896514 T C ADNP2 p.I1073T 0 560.442623 61 WCM119 Plasma 20 47569385 G A AREGEF2 p.M189I 0 38 0.48809584 WCM119 Plasma 2 183088628 G T PDE1A p.H263N 0 56 0.307692 91 WCM119Plasma 22 20800753 C T KLHL22 p.G506R 0 38 0.366337 101 WCM119 Plasma 3148756856 G C HLTF p.R926G 0 57 0.326316 95 WCM119 Plasma 3 56675432 G CFAM208A p.S855C 0 61 0.348624 109 WCM119 Plasma 8 4494994 A T CSMD1p.C58S 0 45 0.148649 74 WCM119 Plasma 9 113243636 A T SVEP1 p.L751I 0 520.310345 87 WCM119 Plasma 10 17905650 G A MRC1L1 p.E581K 0 34 0.54054137 WCM119_Z6_1 Tissue 11 8111755 G T TUB p.S77I 0 50 0.051724 58WCM119_Z6_1 Tissue 1 203134607 T C ADORA1 p.V187A 0 46 0.150943 53WCM119_Z6_1 Tissue 12 57485590 T C NAB2 p.F256L 0 73 0.246914 81WCM119_Z6_1 Tissue 17 38279626 G T MSL1 p.R254I 0 142 0.594828 232WCM119_Z6_1 Tissue 17 60040181 G C MED13 p.L1666V 0 56 0.208333 48WCM119_Z6_1 Tissue 19 55447768 G A NLRP7 p.R721W 0 55 0.164384 73WCM119_Z6_1 Tissue 1 95699815 C T RWDD3 p.S10L 0 41 0.219512 41WCM119_Z6_1 Tissue 19 6222644 C T MLLT1 p.E200K 0 109 0.246269 134WCM119_Z6_1 Tissue 21 43166878 C T RIPK4 p.E243K 0 149 0.083333 132WCM119_Z6_1 Tissue 22 42089894 G A C22orf46 p.R215H 0 72 0.057692 52WCM119_Z6_1 Tissue 3 121353250 C T HCLS1 p.R236H 0 64 0.269231 52WCM119_Z6_1 Tissue 3 130116596 G C COL6A5 p.L1246F 0 116 0.064748 139WCM119_Z6_1 Tissue 3 148756856 G C HLTF p.R926G 0 117 0.326531 147WCM119_Z6_1 Tissue 3 56675432 G C FAM208A p.S855C 0 99 0.363636 88WCM119_Z6_1 Tissue 5 124080030 A C ZNF608 p.L218R 0 32 0.5 34WCM119_Z6_1 Tissue 6 155154029 G A SCAF8 p.V1106I 0 83 0.109756 82WCM119_Z6_1 Tissue 7 117431424 G A CTTNBP2 p.P609L 0 173 0.259459 185WCM119_Z6_1 Tissue 7 15725552 G A MEOX2 p.A159V 0 56 0.190476 42WCM119_Z6_1 Tissue 7 54617755 G A VSTM2A p.V176I 0 106 0.502674 187WCM119_Z6_1 Tissue 8 113420582 G T CSMD3 p.P1857Q 0 59 0.322917 96WCM119_Z6_1 Tissue 8 1497307 C T DLGAP2 p.R150C 0 99 0.206186 97WCM119_Z6_1 Tissue 8 4494994 A T CSMD1 p.C58S 0 69 0.144144 111WCM119_Z6_1 Tissue 15 43783909 C G TP53BP1 p.S105T 0 54 0.075949 79WCM121 Plasma 15 43783910 T C TP53BP1 p.S105G 0 54 0.076923 78 WCM121Plasma 1 144918897 C T PDE4DIP p.R430Q 0 45 0.111111 36 WCM121_Z1_1Tissue 12 122252481 C T SETD1B p.T787M 0 103 0.273684 95 WCM121_Z1_1Tissue 12 22013982 C A ABCC9 p.A783S 0 42 0.202703 74 WCM121_Z1_1 Tissue1 235972899 C A LYST p.G407* 0 206 0.184211 190 WCM121_Z1_1 Tissue 1321306151 C T N6AMT2 p.E113K 0 111 0.109589 73 WCM121_Z1_1 Tissue 1324876763 C T SPATA13 p.P604L 0 141 0.117188 128 WCM121_Z1_1 Tissue 132797822 A G HDAC1 p.K451E 0 43 0.220588 68 WCM121_Z1_1 Tissue 1574290754 G T PML p.G180V 0 85 0.380952 63 WCM121_Z1_1 Tissue 19 39667297T G PAK4 p.V476G 0 125 0.223684 152 WCM121_Z1_1 Tissue 19 40520343 A TZNF546 p.E389V 0 66 0.168831 77 WCM121_Z1_1 Tissue 2 128380840 G A MYO7Bp.V1211I 0 111 0.135922 103 WCM121_Z1_1 Tissue 21 47969722 G A DIP2Ap.R854Q 0 203 0.138776 245 WCM121_Z1_1 Tissue 2 234738282 G A MROH2Ap.R1488H 0 57 0.170455 88 WCM121_Z1_1 Tissue 2 65299398 G C CEP68p.G390R 0 227 0.5 182 WCM121_Z1_1 Tissue 3 197670800 T C IQCG p.E44G 088 0.394231 104 WCM121_Z1_1 Tissue 3 39230287 A G XIRP1 p.L217P 0 2130.156951 223 WCM121_Z1_1 Tissue 3 52883823 G A TMEM110 p.R138C 0 1230.189655 116 WCM121_Z1_1 Tissue 4 39448474 G C KLB p.G710R 0 46 0.26415153 WCM121_Z1_1 Tissue 4 84374518 G C HELQ p.T293S 0 98 0.342593 108WCM121_Z1_1 Tissue 9 133961040 C A LAMC3 p.A1387E 0 72 0.081081 74WCM121_Z1_1 Tissue 9 26923260 G A PLAA p.H319Y 0 36 0.159091 44WCM121_Z1_1 Tissue 9 36110059 A C RECK p.D624A 0 191 0.14359 195WCM121_Z1_1 Tissue 9 84605740 C A SPATA31D1 p.H119N 0 57 0.128205 39WCM121_Z1_1 Tissue 10 27702774 C T PTCHD3 p.A136T 0 66 0.368421 57WCM124_X1_3 Tissue 10 7285660 T C SFMBT2 p.N327S 0 37 0.258065 31WCM124_X1_3 Tissue 11 6478162 G A TRIMS p.P265L 0 122 0.490066 151WCM124_X1_3 Tissue 11 76751319 G A B3GNT6 p.G242S 0 50 0.082192 73WCM124_X1_3 Tissue 1 186043891 C T HMCN1 p.H2720Y 0 37 0.220339 59WCM124_X1_3 Tissue 11 87882847 G T RAB38 p.A160E 0 227 0.067511 237WCM124_X1_3 Tissue 1 215821900 G T USH2A p.P4851H 0 71 0.193548 124WCM124_X1_3 Tissue 12 52467672 G T C12orf44 p.V80F 0 103 0.090164 122WCM124_X1_3 Tissue 1 27690551 G A MAP3K6 p.R241W 0 67 0.256757 74WCM124_X1_3 Tissue 13 27333336 A C GPR12 p.F210C 0 106 0.405882 170WCM124_X1_3 Tissue 14 96783585 C T ATG2B p.R1036H 0 100 0.275 80WCM124_X1_3 Tissue 1 53793511 T C LRP8 p.Q25R 0 42 0.083333 48WCM124_X1_3 Tissue 15 85189436 G A WDR73 p.R166W 0 155 0.433071 127WCM124_X1_3 Tissue 16 57496641 C T POLR2C p.P2L 0 42 0.424242 33WCM124_X1_3 Tissue 17 27064987 T G NEKS p.V347G 0 51 0.166667 66WCM124_X1_3 Tissue 17 37922387 G A IKZF3 p.R396C 0 163 0.108808 193WCM124_X1_3 Tissue 17 40065910 T C ACLY p.D130G 0 189 0.108974 156WCM124_X1_3 Tissue 17 71197854 C T COG1 p.Q630* 0 124 0.26875 160WCM124_X1_3 Tissue 19 45656197 C T NKPD1 p.A278T 0 33 0.444444 36WCM124_X1_3 Tissue 19 6230663 G C MLLT1 p.P113R 0 34 0.36 100WCM124_X1_3 Tissue 2 111395672 G T BUB1 p.H1043N 0 39 0.142857 42WCM124_X1_3 Tissue 5 141334958 G A PCDH12 p.P820L 0 157 0.384615 130WCM124_X1_3 Tissue 6 159636090 C T FNDC1 p.R192W 0 71 0.352113 71WCM124_X1_3 Tissue 6 97001230 A C UFL1 p.T746P 0 48 0.382979 47WCM124_X1_3 Tissue 7 106509446 C A PIK3CG p.Y480* 0 101 0.338462 65WCM124_X1_3 Tissue 9 129458674 G A LMX1B p.V385M 0 176 0.154839 310WCM124_X1_3 Tissue 10 95326847 G T FFAR4 p.V124F 0 196 0.738889 180PM12_Z10_1 Tissue 11 12029948 G A DKK3 p.T61M 0 75 0.131579 38PM12_Z10_1 Tissue 11 17546056 G T USH1C p.P234H 0 139 0.06701 194PM12_Z10_1 Tissue 1 118535220 T C SPAG17 p.I1744V 0 263 0.126354 277PM12_Z10_1 Tissue 1 118579497 T A SPAG17 p.D1110V 0 61 0.126582 79PM12_Z10_1 Tissue 1 158047834 G A KIRREL p.E86K 0 203 0.268012 347PM12_Z10_1 Tissue 11 71944012 C T INPPL1 p.R649* 0 164 0.052083 96PM12_Z10_1 Tissue 1 175957441 C G RFWD2 p.G652A 0 79 0.157658 222PM12_Z10_1 Tissue 1 204948171 G C NFASC p.G651A 0 103 0.06414 343PM12_Z10_1 Tissue 12 123459815 C T OGFOD2 p.A6V 0 70 0.487179 39PM12_Z10_1 Tissue 1 227077810 A T PSEN2 p.I288L 0 140 0.192893 197PM12_Z10_1 Tissue 1 228482627 C G OBSCN p.L3848V 0.002342 427 0.358607488 PM12_Z10_1 Tissue 12 42717823 G C ZCRB1 p.R28G 0 110 0.191011 89PM12_Z10_1 Tissue 13 25281512 G A ATP12A p.G812R 0 44 0.073171 41PM12_Z10_1 Tissue 15 31619458 C G KLF13 p.L15V 0 74 0.322222 90PM12_Z10_1 Tissue 1 53236935 C G ZYG11B p.T147S 0 55 0.307692 39PM12_Z10_1 Tissue 1 53323317 G A ZYG11A p.A302T 0 179 0.085227 176PM12_Z10_1 Tissue 1 62738884 G T KANK4 p.P631Q 0 62 0.0625 48 PM12_Z10_1Tissue 16 30777502 G T RNF40 p.E338* 0 155 0.141553 219 PM12_Z10_1Tissue 17 2323445 C G METTL16 p.R503T 0 149 0.285714 98 PM12_Z10_1Tissue 17 76993090 G T CANT1 p.D205E 0 255 0.11215 214 PM12_Z10_1 Tissue19 35829124 A T CD22 p.S347C 0 216 0.116071 224 PM12_Z10_1 Tissue 1938704297 G A DPF1 p.T316I 0 117 0.149254 67 PM12_Z10_1 Tissue 2040052263 G T CHD6 p.T1475N 0 40 0.462963 54 PM12_Z10_1 Tissue 2044997585 G A ELMO2 p.S636F 0 121 0.078125 128 PM12_Z10_1 Tissue 2108924898 T C SULT1C2 p.I304T 0 131 0.159292 113 PM12_Z10_1 Tissue 2113479447 G A NT5DC4 p.D22N 0 91 0.343284 67 PM12_Z10_1 Tissue 2149854985 A C KIF5C p.E724D 0 150 0.103448 145 PM12_Z10_1 Tissue 2152406251 G C NEB p.L4949V 0 131 0.513369 187 PM12_Z10_1 Tissue 215608610 T A NBAS p.R591S 0 157 0.429577 142 PM12_Z10_1 Tissue 2190315633 A C WDR75 p.Y74S 0 61 0.152 125 PM12_Z10_1 Tissue 2 209138323G T PIKFYVE p.G63V 0 166 0.055556 234 PM12_Z10_1 Tissue 2 239257426 G ATRAF3IP1 p.G435D 0 77 0.107692 65 PM12_Z10_1 Tissue 2 242683147 G AD2HGDH p.G201R 0 140 0.0625 80 PM12_Z10_1 Tissue 2 286134 G T FAM150Bp.T126N 0 52 0.450549 91 PM12_Z10_1 Tissue 2 9083337 A T MBOAT2 p.I93K 044 0.35 40 PM12_Z10_1 Tissue 3 122631875 G T SEMA5B p.T847N 0 40 0.5471753 PM12_Z10_1 Tissue 3 165547604 A T BCHE p.D406E 0 138 0.071942 139PM12_Z10_1 Tissue 3 69242846 C T FRMD4B p.R556Q 0 83 0.090909 66PM12_Z10_1 Tissue 4 109663687 T C ETNPPL p.M485V 0 111 0.377953 127PM12_Z10_1 Tissue 4 68930433 C T TMPRSS11F p.V329I 0 53 0.050955 157PM12_Z10_1 Tissue 5 121487959 C T ZNF474 p.P92S 0 148 0.081818 110PM12_Z10_1 Tissue 5 1244730 G A SLC6A18 p.D502N 0 149 0.64557 79PM12_Z10_1 Tissue 5 140475710 G A PCDHB2 p.V446I 0 135 0.130081 123PM12_Z10_1 Tissue 5 140857128 G A PCDHGC3 p.W482* 0 86 0.060606 66PM12_Z10_1 Tissue 5 166711927 A G TENM2 p.S29G 0 67 0.1625 80 PM12_Z10_1Tissue 5 53815095 T C SNX18 p.M438T 0 305 0.377581 339 PM12_Z10_1 Tissue6 90402844 C T MDN1 p.R3302Q 0 35 0.06383 47 PM12_Z10_1 Tissue 7151873569 T G KMT2C p.N2990T 0 237 0.051672 329 PM12_Z10_1 Tissue 736338762 G A EEPD1 p.G553S 0 56 0.068182 44 PM12_Z10_1 Tissue 7 94989397G A PON3 p.T318I 0 49 0.089552 67 PM12_Z10_1 Tissue 8 142367144 G CGPR20 p.P294A 0 147 0.262948 251 PM12_Z10_1 Tissue 9 113192211 T G SVEP1p.K1868N 0 92 0.414286 140 PM12_Z10_1 Tissue 9 13206032 G T MPDZ p.Q453K0 53 0.107143 56 PM12_Z10_1 Tissue 9 139311463 A C PMPCA p.K232Q 0 1310.358974 156 PM12_Z10_1 Tissue X 16170596 G C GRPR p.S328T 0 93 0.066667120 PM12_Z10_1 Tissue 10 124380665 G A DMBT1 p.V1664M 0 89 0.14433 97WCM131 Plasma 10 13325796 T C PHYH p.E241G 0 79 0.117647 85 WCM131Plasma 10 134750473 C T TTC40 p.M249I 0 41 0.133333 60 WCM131 Plasma 10134895273 G A GPR123 p.V306M 0 42 0.176471 68 WCM131 Plasma 10 25465161A G GPR158 p.E271G 0 36 0.132075 53 WCM131 Plasma 10 50025396 G A WDFY4p.R1816Q 0 42 0.126984 63 WCM131 Plasma 10 5498098 G A NET1 p.V416I 0 490.179104 67 WCM131 Plasma 10 82012967 G T AL359195.1 p.C162F 0 33 0.0850 WCM131 Plasma 10 82013119 G A AL359195.1 p.G213S 0 45 0.210526 76WCM131 Plasma 10 82187167 G A FAM213A p.R164Q 0 72 0.163462 104 WCM131Plasma 11 100820663 G A ARHGAP42 p.A380T 0 70 0.076923 91 WCM131 Plasma11 103006228 T A DYNC2H1 p.F737Y 0 46 0.095238 63 WCM131 Plasma 11104912206 G A CARD16 p.P172L 0 60 0.150685 73 WCM131 Plasma 11 113639557C T ZW10 p.E80K 0 56 0.220588 68 WCM131 Plasma 11 11374269 A G CSNK2A3p.I133T 0 62 0.15625 96 WCM131 Plasma 11 114401611 A G NXPE1 p.L40S 0 310.1 60 WCM131 Plasma 11 114550423 T G NXPE2 p.L24R 0 56 0.075 80 WCM131Plasma 11 114568942 T C NXPE2 p.V103A 0 57 0.197183 71 WCM131 Plasma 11118362527 C T KMT2A p.R1627W 0 45 0.178571 56 WCM131 Plasma 1 111998809A G ATP5F1 p.M109V 0 33 0.166667 60 WCM131 Plasma 11 120041110 T AAP000679.2 p.L198Q 0 36 0.12 50 WCM131 Plasma 11 123676829 G C OR6M1p.P77A 0 45 0.133333 90 WCM131 Plasma 11 124056566 G A OR10D3 p.R197K 035 0.15873 63 WCM131 Plasma 11 124056732 T G OR10D3 p.Y252* 0 420.135593 59 WCM131 Plasma 11 124056787 G A OR10D3 p.V271M 0 35 0.18965558 WCM131 Plasma 1 113265772 C T FAM19A3 p.P84S 0 33 0.075472 53 WCM131Plasma 1 117619377 C G TTF2 p.P502R 0 35 0.197183 71 WCM131 Plasma 1117629855 C T OTOG p.S1402L 0 37 0.076923 65 WCM131 Plasma 11 43428757 AG TTC17 p.I611V 0 31 0.212766 47 WCM131 Plasma 11 48387186 A G OR4C5p.F278L 0 72 0.094118 85 WCM131 Plasma 11 49974261 T C OR4C13 p.M96T 051 0.138889 72 WCM131 Plasma 1 151638469 G A SNX27 p.V323M 0 70 0.13953586 WCM131 Plasma 1 160917793 G A ITLN2 p.R251W 0 51 0.151899 79 WCM131Plasma 11 62863518 A G SLC22A24 p.S339P 0 32 0.104478 67 WCM131 Plasma11 66358007 C T CCDC87 p.R827H 0 37 0.090909 55 WCM131 Plasma 1171118840 G A FMO6P p.V257I 0 59 0.055556 72 WCM131 Plasma 11 73020965 CA ARHGEF17 p.L428M 0 31 0.134615 52 WCM131 Plasma 1 173873176 C ASERPINC1 p.A416S 0 43 0.089286 56 WCM131 Plasma 11 74203308 T A LIPT2p.T190S 0 43 0.112903 62 WCM131 Plasma 11 75439104 C T MOGAT2 p.Q189* 031 0.173333 75 WCM131 Plasma 11 7818410 C T OR5P2 p.R27Q 0 38 0.125 80WCM131 Plasma 11 92088067 A G FAT3 p.N930S 0 53 0.180556 72 WCM131Plasma 11 93457532 C G KIAA1731 p.D2103E 0 36 0.183333 60 WCM131 Plasma11 93458848 C G KIAA1731 p.A2117G 0 41 0.134328 67 WCM131 Plasma 120640926 T C VWA5B1 p.I135T 0 33 0.116667 60 WCM131 Plasma 12 101016068G A GAS2L3 p.E222K 0 61 0.132353 68 WCM131 Plasma 12 101016071 G AGAS2L3 p.D223N 0 61 0.136364 66 WCM131 Plasma 12 113384741 A G OAS3p.D277G 0 43 0.168831 77 WCM131 Plasma 12 129153986 G A TMEM132C p.V444I0 54 0.202247 89 WCM131 Plasma 1 212988440 T A TATDN3 p.V256E 0 360.101695 59 WCM131 Plasma 12 13061554 G A GPRC5A p.R124Q 0 42 0.19512282 WCM131 Plasma 12 130923011 C T RIMBP2 p.A502T 0 40 0.139535 43 WCM131Plasma 12 132401575 C T ULK1 p.T717M 0 58 0.157895 76 WCM131 Plasma 1225565015 T C DNAH14 p.L3088P 0 31 0.298246 57 WCM131 Plasma 1 225569241T G DNAH14 p.F3236C 0 58 0.242857 70 WCM131 Plasma 12 40821867 G A MUC19p.V206I 0 50 0.193182 88 WCM131 Plasma 12 40832161 T C MUC19 p.I567T 049 0.230769 65 WCM131 Plasma 12 40835734 C G MUC19 p.I694M 0 61 0.14942587 WCM131 Plasma 12 40838216 T C MUC19 p.V909A 0 45 0.189655 58 WCM131Plasma 12 50744119 G A FAM186A p.H2166Y 0 32 0.0625 64 WCM131 Plasma 1250754563 T G FAM186A p.K187Q 0 36 0.095238 63 WCM131 Plasma 12 53162813C A KRT76 p.S534I 0 36 0.20339 59 WCM131 Plasma 12 7252566 C T C1RLp.A183T 0 33 0.173913 46 WCM131 Plasma 12 80899901 C A PTPRQ p.Q787K 053 0.095238 84 WCM131 Plasma 1 28208868 C T THEMIS2 p.R345W 0 490.195402 87 WCM131 Plasma 12 96934699 A G C12orf55 p.T671A 0 43 0.14814854 WCM131 Plasma 12 97023939 A T C12orf55 p.N1391I 0 55 0.1125 80 WCM131Plasma 12 97024355 A C C12orf55 p.R1414S 0 62 0.162791 86 WCM131 Plasma12 97186242 C A C12orf55 p.P2939T 0 63 0.157303 89 WCM131 Plasma 13103384712 G A CCDC168 p.T1483M 0 56 0.179775 89 WCM131 Plasma 13112278413 C T RP11-65D24.2 p.P24L 0 37 0.142857 63 WCM131 Plasma 1330829740 C G KATNAL1 p.Q112H 0 35 0.085106 47 WCM131 Plasma 13 32799081C T FRY p.A1643V 0 46 0.1 70 WCM131 Plasma 13 36886481 C T SPG20 p.M539I0 51 0.111111 81 WCM131 Plasma 13 60485919 A G DIAPH3 p.F773L 0 310.213115 61 WCM131 Plasma 13 99462473 C T DOCK9 p.D1735N 0 37 0.14 50WCM131 Plasma 14 100795151 C T SLC25A47 p.S139L 0 31 0.108108 37 WCM131Plasma 14 21498871 C G TPPP2 p.T44R 0 32 0.142857 49 WCM131 Plasma 1423102882 C A OR6J1 p.V279L 0 31 0.075472 53 WCM131 Plasma 14 51368610 AG ABHD12B p.I282V 0 68 0.15942 69 WCM131 Plasma 14 59988324 C T CCDC175p.S689N 0 54 0.183333 60 WCM131 Plasma 1 49119120 A G AGBL4 p.I243T 0 400.2 65 WCM131 Plasma 15 23609550 G T GOLGA8S p.E470* 0 55 0.159091 44WCM131 Plasma 1 52747414 G A ZFYVE9 p.C984Y 0 33 0.147541 61 WCM131Plasma 1 53329820 T G ZYG11A p.H439Q 0 43 0.105263 57 WCM131 Plasma 1533445701 A G FMN1 p.L472P 0 31 0.177419 62 WCM131 Plasma 15 33446947 A CFMN1 p.S57A 0 38 0.114286 70 WCM131 Plasma 15 42342824 T G PLA2G4Ep.E26D 0 53 0.073529 68 WCM131 Plasma 15 43783909 C G TP53BP1 p.S105T 050 0.087719 57 WCM131 Plasma 15 43783910 T C TP53BP1 p.S105G 0 490.089286 56 WCM131 Plasma 1 57349308 C T C8A p.S270L 0 44 0.118421 76WCM131 Plasma 15 81214459 G A KIAA1199 p.R728Q 0 53 0.098765 81 WCM131Plasma 16 14345779 G A MKL2 p.A811T 0 33 0.137931 58 WCM131 Plasma 161484528 G A CCDC154 p.R636C 0 31 0.111111 72 WCM131 Plasma 16 2161666 GA PKD1 p.P1168S 0 51 0.148649 74 WCM131 Plasma 16 30772988 C T C16orf93p.A28T 0 56 0.152542 59 WCM131 Plasma 16 4787917 G T C16orf71 p.W82C 031 0.146341 41 WCM131 Plasma 16 67314790 C T PLEKHG4 p.R201W 0 31 0.1560 WCM131 Plasma 16 80584435 A C DYNLRB2 p.I91L 0 44 0.118421 76 WCM131Plasma 16 85144059 G C FAM92B p.Q10E 0 37 0.21875 64 WCM131 Plasma 1718881605 C A FAM83G p.Q458H 0 45 0.145161 62 WCM131 Plasma 17 26822793 GA SLC13A2 p.V477M 0 33 0.203125 64 WCM131 Plasma 17 39538524 C T KRT34p.C34Y 0 36 0.114286 70 WCM131 Plasma 17 4058094 C T CYB5D2 p.P173L 0 420.181818 66 WCM131 Plasma 17 48606459 G C MYCBPAP p.L921F 0 52 0.06756874 WCM131 Plasma 17 55184494 G T AKAP1 p.A557S 0 31 0.121951 41 WCM131Plasma 17 6023854 G A WSCD1 p.R534H 0 75 0.223684 76 WCM131 Plasma 1766039102 T C KPNA2 p.M218T 0 68 0.162162 74 WCM131 Plasma 17 74470523 GA RHBDF2 p.R495W 0 35 0.227273 66 WCM131 Plasma 17 76454668 C G DNAH17p.R3314T 0 36 0.130435 46 WCM131 Plasma 17 80401897 G A C17orf62 p.P183S0 43 0.115385 78 WCM131 Plasma 18 13096186 A G CEP192 p.D1550G 0 330.160714 56 WCM131 Plasma 18 44773382 A T SKOR2 p.C725S 0 32 0.09375 32WCM131 Plasma 18 72021145 T A C18orf63 p.F548Y 0 44 0.169811 53 WCM131Plasma 19 1535205 G C PLK5 p.G323R 0 35 0.137931 58 WCM131 Plasma 191650226 C A TCF3 p.A8S 0 69 0.097561 82 WCM131 Plasma 19 19162980 A GARMC6 p.K277E 0 39 0.222222 63 WCM131 Plasma 19 19427258 G A SUGP1p.A60V 0 44 0.071429 42 WCM131 Plasma 19 37482151 A G ZNF568 p.D96G 0 490.057143 70 WCM131 Plasma 19 37487632 G A ZNF568 p.A283T 0 32 0.12 50WCM131 Plasma 19 37488299 A G ZNF568 p.E505G 0 32 0.183333 60 WCM131Plasma 19 37488472 C G ZNF568 p.P563A 0 47 0.115942 69 WCM131 Plasma 1937488481 G C ZNF568 p.G566R 0 48 0.121212 66 WCM131 Plasma 19 40978640 GA SPTBN4 p.A38T 0 37 0.139535 43 WCM131 Plasma 19 44153202 A G PLAURp.I283T 0 33 0.210526 57 WCM131 Plasma 19 52097261 C G AC018755.1p.R105P 0 40 0.142857 35 WCM131 Plasma 19 53643919 C T ZNF347 p.R721H 061 0.179775 89 WCM131 Plasma 19 58352806 T C ZNF587B p.V255A 0 760.293478 92 WCM131 Plasma 19 58353003 G A ZNF587B p.A321T 0 72 0.26436887 WCM131 Plasma 19 6468102 C T DENND1C p.D607N 0 42 0.070175 57 WCM131Plasma 19 7711198 C T STXBP2 p.R474C 0 43 0.131579 76 WCM131 Plasma 199407205 G A ZNF699 p.S292L 0 32 0.098361 61 WCM131 Plasma 19 9801365 T GZNF812 p.T272P 0 41 0.09434 53 WCM131 Plasma 20 1210647 T C RAD21L1p.C90R 0 34 0.173077 52 WCM131 Plasma 20 1224774 A C RAD21L1 p.H423P 043 0.12963 54 WCM131 Plasma 20 31466534 C T EFCAB8 p.R118C 0 48 0.10769265 WCM131 Plasma 20 56796445 C T ANKRD60 p.V226M 0 38 0.203704 54 WCM131Plasma 20 61522352 C G DIDO1 p.Q1167H 0 54 0.149425 87 WCM131 Plasma 2102642617 T C IL1R2 p.I311T 0 50 0.1 70 WCM131 Plasma 2 10959475 G CPDIA6 p.P34A 0 43 0.206897 58 WCM131 Plasma 2 113480339 G A NT5DC4p.R147H 0 48 0.12069 58 WCM131 Plasma 2 121223274 C T FLJ14816 p.C138Y 032 0.294118 68 WCM131 Plasma 2 1320143 C T SNTG2 p.T495M 0 45 0.20833372 WCM131 Plasma 2 167108386 G A SCN9A p.R1121W 0 52 0.178947 95 WCM131Plasma 2 170034424 T C LRP2 p.R3428G 0 44 0.115942 69 WCM131 Plasma 2170488368 T A PPIG p.F285Y 0 38 0.054054 74 WCM131 Plasma 2 172379099 CT CYBRD1 p.S15L 0 44 0.153846 65 WCM131 Plasma 2 175318530 C G GPR155p.C604S 0 58 0.1125 80 WCM131 Plasma 2 179665289 C T TTN p.R139Q 0 390.085714 70 WCM131 Plasma 2 179751485 T G CCDC141 p.Q507H 0 38 0.12121266 WCM131 Plasma 2 186668935 A G FSIP2 p.M4968V 0 48 0.130435 92 WCM131Plasma 22 18209989 G A BCL2L13 p.E383K 0 35 0.071429 42 WCM131 Plasma 2221330818 G A AIFM3 p.G341S 0 41 0.104478 67 WCM131 Plasma 22 25291215 GA SGSM1 p.R715H 0 31 0.066667 60 WCM131 Plasma 22 29138301 A G HSCBp.Y73C 0 73 0.083333 72 WCM131 Plasma 2 231865090 T C SPATA3 p.I104T 032 0.097561 41 WCM131 Plasma 22 32113233 C T PRR14L p.E198K 0 45 0.12556 WCM131 Plasma 22 37398201 C A TEX33 p.A56S 0 50 0.136364 88 WCM131Plasma 2 238289980 G C COL6A3 p.T492S 0 31 0.142857 56 WCM131 Plasma 2239003414 C T FAM227A p.R369Q 0 36 0.203125 64 WCM131 Plasma 22 41513682A G EP300 p.I196V 0 43 0.117647 51 WCM131 Plasma 2 242606080 G A ATG4Bp.V187I 0 33 0.108696 46 WCM131 Plasma 2 25013348 T G PTRHD1 p.I119L 060 0.166667 84 WCM131 Plasma 2 32733203 G A BIRC6 p.R3286Q 0 69 0.15555690 WCM131 Plasma 2 36706700 A C CRIM1 p.H412P 0 32 0.128205 39 WCM131Plasma 2 44174907 T C LRPPRC p.H643R 0 46 0.174603 63 WCM131 Plasma 3112732817 A C C3orf17 p.F108L 0 48 0.168831 77 WCM131 Plasma 3 131442345T C CPNE4 p.H102R 0 35 0.094595 74 WCM131 Plasma 3 132242405 G A DNAJC13p.V1970M 0 51 0.135135 74 WCM131 Plasma 3 132424634 C T NPHP3 p.A434T 063 0.086957 69 WCM131 Plasma 3 149485521 T C ANKUB1 p.M310V 0 430.169231 65 WCM131 Plasma 3 20042834 C T PP2D1 p.A260T 0 34 0.138462 65WCM131 Plasma 3 36899394 C T TRANK1 p.V563M 0 43 0.130435 69 WCM131Plasma 3 49847804 C T UBA7 p.V509M 0 32 0.121951 41 WCM131 Plasma 357414097 T A DNAH12 p.K1754N 0 71 0.209877 81 WCM131 Plasma 3 67411166 AG SUCLG2 p.Y404H 0 52 0.111111 54 WCM131 Plasma 3 98235681 A G CLDND1p.I195T 0 38 0.086957 69 WCM131 Plasma 4 100575711 C T RP11- p.R32Q 0 630.153846 78 WCM131 Plasma 766F14.2 4 104084352 T C CENPE p.Q595R 0 410.1 80 WCM131 Plasma 4 114458513 G T CAMK2D p.D167E 0 39 0.1 60 WCM131Plasma 4 135121601 C T PABPC4L p.V192I 0 56 0.297872 47 WCM131 Plasma 4141383121 A T RP11- p.L242M 0 74 0.130435 92 WCM131 Plasma 542P2.1 4152203391 G A PRSS48 p.V103I 0 48 0.164179 67 WCM131 Plasma 4 17690072 TC FAM184B p.Q524R 0 40 0.131868 91 WCM131 Plasma 4 20619178 C T SLIT2p.A1418V 0 44 0.173913 69 WCM131 Plasma 4 2460546 G A RP11- p.A165T 0 390.152174 46 WCM131 Plasma 503N18.3 4 26487482 T C CCKAR p.I135V 0 460.153846 65 WCM131 Plasma 4 3189510 T C HTT p.C1708R 0 42 0.151515 66WCM131 Plasma 4 438189 G A ZNF721 p.P11S 0 40 0.096154 52 WCM131 Plasma4 48851970 G A OCIAD1 p.C83Y 0 56 0.138462 65 WCM131 Plasma 4 79291115 AT FRAS1 p.D949V 0 48 0.152941 85 WCM131 Plasma 4 83776079 G A SEC31Ap.P662L 0 75 0.093023 86 WCM131 Plasma 5 112175240 G C APC p.E1317Q 0 330.137931 58 WCM131 Plasma 5 140755929 C G PCDHGA6 p.T760S 0 45 0.11111163 WCM131 Plasma 5 149006768 A G ARHGEF37 p.I532V 0 45 0.145833 48WCM131 Plasma 5 157102159 G A C5orf52 p.R91Q 0 90 0.17 100 WCM131 Plasma5 32088073 A G PDZD2 p.I1507V 0 50 0.060606 66 WCM131 Plasma 5 36052004A T UGT3A2 p.F93L 0 65 0.130435 69 WCM131 Plasma 5 43245944 G A NIM1p.D23N 0 34 0.150943 53 WCM131 Plasma 5 55237432 A C IL6ST p.D745E 0 570.152941 85 WCM131 Plasma 5 74066543 A G NSA2 p.K144E 0 37 0.111111 54WCM131 Plasma 5 74066544 A C NSA2 p.K144T 0 36 0.115385 52 WCM131 Plasma5 74442964 T C ANKRD31 p.R758G 0 38 0.177419 62 WCM131 Plasma 5 86703952A T CCNH p.S122R 0 44 0.092308 65 WCM131 Plasma 5 93987532 C A ANKRD32p.S288R 0 52 0.109375 64 WCM131 Plasma 6 131540832 A C AKAP7 p.E245A 049 0.133333 75 WCM131 Plasma 6 167585654 G A TCP10L2 p.A8T 0 40 0.21311561 WCM131 Plasma 6 27277665 G A POM121L2 p.P762L 0 35 0.169492 59 WCM131Plasma 6 28964347 C T ZNF311 p.M144I 0 32 0.207547 53 WCM131 Plasma 638029537 C T ZFAND3 p.P94L 0 50 0.160494 81 WCM131 Plasma 6 49479750 T CGLYATL3 p.M16T 0 45 0.173913 46 WCM131 Plasma 6 49489397 C A GLYATL3p.A118D 0 57 0.162162 74 WCM131 Plasma 6 53385691 C T GCLC p.G111R 0 500.162162 74 WCM131 Plasma 6 64694354 C T EYS p.R2326Q 0 56 0.227273 88WCM131 Plasma 6 65301217 G A EYS p.R1515W 0 43 0.064516 62 WCM131 Plasma6 65301679 T C EYS p.I1361V 0 38 0.101695 59 WCM131 Plasma 6 65303100 TC EYS p.I1263V 0 71 0.116279 86 WCM131 Plasma 6 74183172 C T MTO1p.T207M 0 58 0.098765 81 WCM131 Plasma 6 74528127 A G CD109 p.R1310G 049 0.12 75 WCM131 Plasma 6 90660390 C T BACH2 p.A479T 0 47 0.123077 65WCM131 Plasma 7 121733190 G A AASS p.P560S 0 38 0.151515 33 WCM131Plasma 7 12406989 C G VWDE p.K964N 0 66 0.151515 99 WCM131 Plasma 7141838362 C G RP11- p.F327L 0 50 0.264368 87 WCM131 Plasma 1220K2.2 7144094613 G T NOBOX p.P599H 0 34 0.209302 43 WCM131 Plasma 7 150932381 TG CHPF2 p.F171V 0 33 0.159091 44 WCM131 Plasma 7 150932382 T C CHPF2p.F171S 0 33 0.162791 43 WCM131 Plasma 7 45124286 A G NACAD p.V498A 0 450.115385 78 WCM131 Plasma 7 87053289 G A ABCB4 p.T715I 0 33 0.149254 67WCM131 Plasma 7 87822541 G A ADAM22 p.R896Q 0 36 0.089552 67 WCM131Plasma 7 91779971 T G LRRD1 p.I719L 0 48 0.2 60 WCM131 Plasma 7 99145678C G FAM200A p.R118P 0 31 0.189189 37 WCM131 Plasma 8 103851047 T G AZIN1p.K125T 0 49 0.103448 58 WCM131 Plasma 8 120103453 A G COLEC10 p.K96E 033 0.111111 63 WCM131 Plasma 8 133092138 G A HHLA1 p.P251L 0 51 0.32812564 WCM131 Plasma 8 17143907 A T VPS37A p.M389L 0 34 0.262295 61 WCM131Plasma 8 17170887 T A MTMR7 p.M297L 0 31 0.207547 53 WCM131 Plasma 823150878 T G R3HCC1 p.L403R 0 32 0.135135 37 WCM131 Plasma 8 70476314 AG SULF1 p.Q35R 0 50 0.1 60 WCM131 Plasma 8 90936893 T A OSGIN2 p.D217E 032 0.12963 54 WCM131 Plasma 9 100405634 G A NCBP1 p.V125M 0 48 0.08823568 WCM131 Plasma 9 116346651 G A RGS3 p.G987S 0 44 0.207547 53 WCM131Plasma 9 134314416 A G PRRC2B p.Q146R 0 45 0.171053 76 WCM131 Plasma 934726671 G A FAM205A p.T189M 0 39 0.193548 62 WCM131 Plasma 9 37888096 TC SLC25A51 p.H151R 0 45 0.115942 69 WCM131 Plasma 9 38615698 C TANKRD18A p.E130K 0 74 0.125 96 WCM131 Plasma 9 5358304 T C PLGRKTp.M127V 0 42 0.081633 49 WCM131 Plasma 9 96312954 A G FAM120A p.D752G 041 0.130435 69 WCM131 Plasma 10 124380665 G A DMBT1 p.V1664M 0 1410.408163 98 WCM131_Z1_1 Tissue 10 12940543 C A CCDC3 p.R229L 0 1060.120301 133 WCM131_Z1_1 Tissue 10 13325796 T C PHYH p.E241G 0 710.636364 66 WCM131_Z1_1 Tissue 10 30915154 T C LYZL2 p.T106A 0 990.367925 106 WCM131_Z1_1 Tissue 10 47669277 C G ANTXRL p.P259A 0 820.383333 60 WCM131_Z1_1 Tissue 10 50013402 T C WDFY4 p.S1528P 0 820.392857 84 WCM131_Z1_1 Tissue 10 50025396 G A WDFY4 p.R1816Q 0 1670.389262 149 WCM131_Z1_1 Tissue 10 50339754 G T FAM170B p.D252E 0 3800.362319 207 WCM131_Z1_1 Tissue 10 50339962 A T FAM170B p.L183Q 0 1560.405405 111 WCM131_Z1_1 Tissue 10 5498098 G A NET1 p.V416I 0 530.604651 43 WCM131_Z1_1 Tissue 10 6533711 G A PRKCQ p.P242S 0.009346 1070.213836 159 WCM131_Z1_1 Tissue 10 76994877 C T COMTD1 p.V130M 0 340.543478 46 WCM131_Z1_1 Tissue 10 92677567 A T ANKRD1 p.H158Q 0 1020.352941 119 WCM131_Z1_1 Tissue 10 94659361 G A EXOC6 p.E140K 0 36 0.1540 WCM131_Z1_1 Tissue 1 103381192 C A COL11A1 p.V1271L 0 48 0.545455 33WCM131_Z1_1 Tissue 11 113639557 C T ZW10 p.E80K 0 106 0.625 88WCM131_Z1_1 Tissue 11 116633658 C T BUD13 p.R216K 0 78 0.451613 31WCM131_Z1_1 Tissue 11 123600380 C T ZNF202 p.A186T 0 113 0.732394 71WCM131_Z1_1 Tissue 11 123676829 G C OR6M1 p.P77A 0 144 0.118644 59WCM131_Z1_1 Tissue 11 124056566 G A OR10D3 p.R197K 0 94 0.111111 63WCM131_Z1_1 Tissue 11 17393644 A G NCR3LG1 p.H317R 0 272 0.403941 203WCM131_Z1_1 Tissue 11 17629855 C T OTOG p.S1402L 0 197 0.238806 67WCM131_Z1_1 Tissue 11 49974261 T C OR4C13 p.M96T 0 73 0.5 38 WCM131_Z1_1Tissue 1 151638469 G A SNX27 p.V323M 0 57 0.178571 84 WCM131_Z1_1 Tissue1 152059754 G A TCHHL1 p.P135L 0 109 0.608295 217 WCM131_Z1_1 Tissue 115322790 G T OR51B4 p.Y129* 0 52 0.512821 39 WCM131_Z1_1 Tissue 1155872925 T G OR8H2 p.M136R 0 147 0.183673 98 WCM131_Z1_1 Tissue 115653623 T G TRIM34 p.L21R 0 127 0.38961 77 WCM131_Z1_1 Tissue 1156594952 C T HAPLN2 p.R267* 0 107 0.151899 79 WCM131_Z1_1 Tissue 1157080394 A C TNKS1BP1 p.Y590D 0 212 0.39823 113 WCM131_Z1_1 Tissue 115708540 A G FHAD1 p.I1325V 0 64 0.563636 55 WCM131_Z1_1 Tissue 1158368948 G T OR10T2 p.F103L 0 203 0.285124 242 WCM131_Z1_1 Tissue 1160718227 C G SLAMF7 p.S100* 0 154 0.11215 107 WCM131_Z1_1 Tissue 1160917793 G A ITLN2 p.R251W 0 93 0.15 100 WCM131_Z1_1 Tissue 11 62886800G C SLC22A24 p.R172G 0 168 0.33945 109 WCM131_Z1_1 Tissue 11 65620182 CT SNX32 p.R332W 0 84 0.383562 73 WCM131_Z1_1 Tissue 11 6569896 G A DNHD1p.V2374M 0 72 0.803571 56 WCM131_Z1_1 Tissue 11 66358007 C T CCDC87p.R827H 0 67 0.474576 59 WCM131_Z1_1 Tissue 11 66472775 G A SPTBN2p.R658W 0 35 0.342857 35 WCM131_Z1_1 Tissue 11 66638660 C T PC p.V166I 067 0.292308 65 WCM131_Z1_1 Tissue 11 7022448 T C ZNF214 p.M156V 0 1680.392593 135 WCM131_Z1_1 Tissue 1 171112490 C T FMO6P p.Q105* 0 90 0.5250 WCM131_Z1_1 Tissue 11 74203308 T A LIPT2 p.T190S 0 132 0.339623 106WCM131_Z1_1 Tissue 11 7818410 C T OR5P2 p.R27Q 0 102 0.325843 89WCM131_Z1_1 Tissue 1 179544941 G A NPHS2 p.P20L 0 131 0.4 70 WCM131_Z1_1Tissue 1 182369105 C T TEDDM1 p.M172I 0 58 0.285714 63 WCM131_Z1_1Tissue 1 183201936 C T LAMC2 p.L722F 0 114 0.198347 121 WCM131_Z1_1Tissue 11 93457532 C G KIAA1731 p.D2103E 0 230 0.565657 99 WCM131_Z1_1Tissue 11 93458848 C G KIAA1731 p.A2117G 0 64 0.162162 37 WCM131_Z1_1Tissue 11 95561083 G A CEP57 p.G340D 0 48 0.548387 31 WCM131_Z1_1 Tissue1 197889142 C T LHX9 p.A72V 0 52 0.131579 38 WCM131_Z1_1 Tissue 121009189 T G KIF17 p.E807A 0 86 0.09375 64 WCM131_Z1_1 Tissue 12104461767 C T HCFC2 p.P119S 0 53 0.295455 44 WCM131_Z1_1 Tissue 12113384741 A G OAS3 p.D277G 0 114 0.342105 76 WCM131_Z1_1 Tissue 12128900005 G A TMEM132C p.V272I 0 75 0.447368 76 WCM131_Z1_1 Tissue 12129153986 G A TMEM132C p.V444I 0 34 0.484848 33 WCM131_Z1_1 Tissue 1212939892 G A APOLD1 p.R49Q 0 34 0.711111 45 WCM131_Z1_1 Tissue 1212988440 T A TATDN3 p.V256E 0 128 0.064 125 WCM131_Z1_1 Tissue 1213061554 G A GPRC5A p.R124Q 0 100 0.565217 115 WCM131_Z1_1 Tissue 12132401575 C T ULK1 p.T717M 0 183 0.458065 155 WCM131_Z1_1 Tissue 12132589038 A G EP400NL p.D158G 0 59 0.086957 46 WCM131_Z1_1 Tissue 12133803551 G C ANHX p.S230C 0 138 0.481481 108 WCM131_Z1_1 Tissue 1237754229 C A RYR2 p.T1366N 0 138 0.390244 82 WCM131_Z1_1 Tissue 1238053787 G A ZP4 p.T50M 0 124 0.6625 80 WCM131_Z1_1 Tissue 12 40835734C G MUC19 p.I694M 0 54 0.435484 62 WCM131_Z1_1 Tissue 12 50744119 G AFAM186A p.H2166Y 0 101 0.27907 86 WCM131_Z1_1 Tissue 12 5155046 G AKCNA5 p.R578K 0 52 0.638095 105 WCM131_Z1_1 Tissue 12 53685589 G C ESPL1p.R1879P 0 144 0.195652 92 WCM131_Z1_1 Tissue 12 6566837 C G TAPBPLp.D277E 0 123 0.15534 206 WCM131_Z1_1 Tissue 12 65857067 G A MSRB3p.A182T 0 71 0.5 58 WCM131_Z1_1 Tissue 12 70351684 C A MYRFL p.L845M 053 0.285714 42 WCM131_Z1_1 Tissue 12 7252566 C T C1RL p.A183T 0 3630.677054 353 WCM131_Z1_1 Tissue 12 80655852 T C OTOGL p.C656R 0 1710.615385 65 WCM131_Z1_1 Tissue 12 80899901 C A PTPRQ p.Q787K 0 52 0.3540 WCM131_Z1_1 Tissue 12 81627216 C G ACSS3 p.A562G 0 62 0.19403 67WCM131_Z1_1 Tissue 12 96131658 C G NTN4 p.G284R 0 106 0.307692 104WCM131_Z1_1 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0.109091 110WCM131_Z2_1 Tissue 12 97023939 A T C12orf55 p.N1391I 0 107 0.184 125WCM131_Z2_1 Tissue 13 103384712 G A CCDC168 p.T1483M 0 129 0.088 125WCM131_Z2_1 Tissue 13 103388015 C G CCDC168 p.G382A 0 257 0.071111 225WCM131_Z2_1 Tissue 13 112278413 C T RP11- p.P24L 0 74 0.2 65 WCM131_Z2_1Tissue 65D24.2 13 113731372 G A MCF2L p.V533M 0 63 0.2 70 WCM131_Z2_1Tissue 13 25367445 G A RNF17 p.D401N 0 113 0.173913 69 WCM131_Z2_1Tissue 13 29246531 G C POMP p.G107A 0 60 0.173913 46 WCM131_Z2_1 Tissue13 36764114 G A SOHLH2 p.L204F 0 101 0.214286 126 WCM131_Z2_1 Tissue 1336886481 C T SPG20 p.M539I 0 171 0.193103 145 WCM131_Z2_1 Tissue 1360485919 A G DIAPH3 p.F773L 0 49 0.232558 43 WCM131_Z2_1 Tissue 136557401 A G ADPRHL2 p.Y164C 0 81 0.2 50 WCM131_Z2_1 Tissue 1 39799329 GT MACF1 p.E2362* 0 144 0.123188 138 WCM131_Z2_1 Tissue 1 39799330 A GMACF1 p.E2362G 0 144 0.123188 138 WCM131_Z2_1 Tissue 13 99738554 G ADOCK9 p.R18W 0 44 0.172414 58 WCM131_Z2_1 Tissue 14 100795151 C TSLC25A47 p.S139L 0 93 0.053571 56 WCM131_Z2_1 Tissue 14 21899631 C TCHD8 p.V58M 0.006289 159 0.282258 124 WCM131_Z2_1 Tissue 14 23102704 G TOR6J1 p.P338Q 0 134 0.159664 119 WCM131_Z2_1 Tissue 14 23102882 C AOR6J1 p.V279L 0 102 0.222222 117 WCM131_Z2_1 Tissue 14 23102896 A GOR6J1 p.L274S 0 227 0.188341 223 WCM131_Z2_1 Tissue 14 23102969 G AOR6J1 p.P250S 0 129 0.188525 122 WCM131_Z2_1 Tissue 1 43240963 T GC1orf50 p.I166M 0 124 0.16 100 WCM131_Z2_1 Tissue 1 43903355 A T SZT2p.Y2070F 0 139 0.157534 146 WCM131_Z2_1 Tissue 14 61180321 G A SIX4p.S717L 0 97 0.156627 83 WCM131_Z2_1 Tissue 14 77948908 C G ISM2 p.A244P0 165 0.198864 176 WCM131_Z2_1 Tissue 1 49119120 A G AGBL4 p.I243T 0 960.186667 75 WCM131_Z2_1 Tissue 14 92040673 C T AL133373.1 p.G95E 0 810.21978 91 WCM131_Z2_1 Tissue 1 52747414 G A ZFYVE9 p.C984Y 0 630.090909 44 WCM131_Z2_1 Tissue 15 29418520 C T FAM189A1 p.R393H 0 550.181818 55 WCM131_Z2_1 Tissue 15 29418574 T C FAM189A1 p.H375R 0 650.333333 60 WCM131_Z2_1 Tissue 1 53329820 T G ZYG11A p.H439Q 0 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Tissue 18 46146079 A GCTIF p.D48G 0 57 0.15 40 WCM131_Z2_1 Tissue 18 47812423 G T CXXC1p.S143Y 0 148 0.216561 157 WCM131_Z2_1 Tissue 18 5890777 T A TMEM200Cp.E429V 0 42 0.319149 47 WCM131_Z2_1 Tissue 18 72021145 T A C18orf63p.F548Y 0 89 0.245902 122 WCM131_Z2_1 Tissue 19 11350560 C T C19orf80p.R83W 0 65 0.196078 51 WCM131_Z2_1 Tissue 19 14029592 C T CC2D1Ap.S327L 0 31 0.186047 43 WCM131_Z2_1 Tissue 19 14743808 A C EMR3 p.F523C0 91 0.15625 64 WCM131_Z2_1 Tissue 19 1533972 C G PLK5 p.L253V 0 980.306667 75 WCM131_Z2_1 Tissue 19 1535205 G C PLK5 p.G323R 0 76 0.3013773 WCM131_Z2_1 Tissue 19 1650226 C A TCF3 p.A8S 0 160 0.111111 135WCM131_Z2_1 Tissue 19 1754193 C G ONECUT3 p.L178V 0 45 0.142857 42WCM131_Z2_1 Tissue 19 19162980 A G ARMC6 p.K277E 0 257 0.124464 233WCM131_Z2_1 Tissue 19 19746315 G A GMIP p.A490V 0 39 0.157895 38WCM131_Z2_1 Tissue 19 22497445 G A ZNF729 p.C409Y 0 107 0.108434 83WCM131_Z2_1 Tissue 19 32844888 C G ZNF507 p.I384M 0 46 0.128205 39WCM131_Z2_1 Tissue 19 37487975 G A ZNF568 p.R397H 0 174 0.207692 130WCM131_Z2_1 Tissue 19 38861424 A T CATSPERG p.M1158L 0 127 0.197368 76WCM131_Z2_1 Tissue 19 40978640 G A SPTBN4 p.A38T 0 89 0.22449 98WCM131_Z2_1 Tissue 19 4283173 C T SHD p.R176W 0 48 0.081081 37WCM131_Z2_1 Tissue 19 52097261 C G AC018755.1 p.R105P 0 58 0.107143 56WCM131_Z2_1 Tissue 19 52570714 C G ZNF841 p.V25L 0 56 0.381818 55WCM131_Z2_1 Tissue 19 52888245 A G ZNF880 p.K471R 0 91 0.40625 128WCM131_Z2_1 Tissue 19 53643919 C T ZNF347 p.R721H 0 80 0.458824 85WCM131_Z2_1 Tissue 19 56028918 C T SSC5D p.P1092L 0 33 0.146341 41WCM131_Z2_1 Tissue 19 56544053 C T NLRP5 p.Q785* 0 31 0.26087 46WCM131_Z2_1 Tissue 19 56717333 C A ZSCAN5C p.S17R 0 167 0.063107 206WCM131_Z2_1 Tissue 19 57335912 C T PEG3 p.G38S 0 164 0.125 184WCM131_Z2_1 Tissue 19 58352806 T C ZNF587B p.V255A 0 54 0.512821 39WCM131_Z2_1 Tissue 19 58353003 G A ZNF587B p.A321T 0 42 0.461538 78WCM131_Z2_1 Tissue 19 6468102 C T DENND1C p.D607N 0 83 0.090909 66WCM131_Z2_1 Tissue 19 7711198 C T STXBP2 p.R474C 0 80 0.105263 95WCM131_Z2_1 Tissue 19 8953449 G T MBD3L1 p.S32I 0 175 0.148387 155WCM131_Z2_1 Tissue 19 9407205 G A ZNF699 p.S292L 0.006494 154 0.132743113 WCM131_Z2_1 Tissue 20 1224774 A C RAD21L1 p.H423P 0 111 0.166667 54WCM131_Z2_1 Tissue 20 52645167 C A BCAS1 p.V163F 0 52 0.222222 45WCM131_Z2_1 Tissue 20 56796445 C T ANKRD60 p.V226M 0 106 0.17094 117WCM131_Z2_1 Tissue 20 61522352 C G DIDO1 p.Q1167H 0 88 0.105263 95WCM131_Z2_1 Tissue 2 102642617 T C IL1R2 p.I311T 0 173 0.25 144WCM131_Z2_1 Tissue 2 10959475 G C PDIA6 p.P34A 0 146 0.236025 161WCM131_Z2_1 Tissue 2 113480339 G A NT5DC4 p.R147H 0 191 0.198718 156WCM131_Z2_1 Tissue 2 121223274 C T FLJ14816 p.C138Y 0 55 0.365385 52WCM131_Z2_1 Tissue 21 28296469 G A ADAMTS5 p.T899M 0 71 0.083333 72WCM131_Z2_1 Tissue 2 128408826 G A GPR17 p.V201M 0 76 0.237288 59WCM131_Z2_1 Tissue 2 1320143 C T SNTG2 p.T495M 0 80 0.598039 102WCM131_Z2_1 Tissue 21 44841593 C T SIK1 p.D142N 0 119 0.201493 134WCM131_Z2_1 Tissue 21 47421284 G A COL6A1 p.R647Q 0 193 0.163636 165WCM131_Z2_1 Tissue 2 152515620 G T NEB p.Q2012K 0 107 0.188976 127WCM131_Z2_1 Tissue 2 15534469 A G NBAS p.S1047P 0 191 0.127451 204WCM131_Z2_1 Tissue 2 1652072 C A PXDN p.Q1160H 0 152 0.136126 191WCM131_Z2_1 Tissue 2 167108386 G A SCN9A p.R1121W 0 176 0.186047 129WCM131_Z2_1 Tissue 2 170034424 T C LRP2 p.R3428G 0 85 0.181818 66WCM131_Z2_1 Tissue 2 170488368 T A PPIG p.F285Y 0 46 0.275862 58WCM131_Z2_1 Tissue 2 173292556 G T ITGA6 p.A14S 0 33 0.081081 37WCM131_Z2_1 Tissue 2 179665289 C T TTN p.R139Q 0 180 0.190722 194WCM131_Z2_1 Tissue 2 186659184 C A FSIP2 p.Q2441K 0 41 0.142857 56WCM131_Z2_1 Tissue 2 19553475 G A OSR1 p.P31L 0 240 0.163743 171WCM131_Z2_1 Tissue 2 196619105 T C DNAH7 p.Y3907C 0 49 0.266667 60WCM131_Z2_1 Tissue 2 207310189 T G ADAM23 p.S125A 0 86 0.242105 95WCM131_Z2_1 Tissue 2 215646030 C T BARD1 p.D190N 0 103 0.153846 130WCM131_Z2_1 Tissue 2 220479221 C T STK11IP p.S941F 0 78 0.108434 83WCM131_Z2_1 Tissue 22 21330818 G A AIFM3 p.G341S 0 123 0.165414 133WCM131_Z2_1 Tissue 22 22892382 A T PRAME p.V240E 0 176 0.202247 178WCM131_Z2_1 Tissue 2 228131783 C G COL4A3 p.H495D 0 186 0.139073 151WCM131_Z2_1 Tissue 22 31008882 G A TCN2 p.G94S 0 126 0.275591 127WCM131_Z2_1 Tissue 2 231865090 T C SPATA3 p.I104T 0 71 0.073529 68WCM131_Z2_1 Tissue 22 32081748 C A PRR14L p.G2074V 0 164 0.171875 192WCM131_Z2_1 Tissue 22 32113233 C T PRR14L p.E198K 0 111 0.156863 102WCM131_Z2_1 Tissue 2 238289984 C G COL6A3 p.D491H 0 82 0.146067 89WCM131_Z2_1 Tissue 22 39003414 C T FAM227A p.R369Q 0 167 0.20438 137WCM131_Z2_1 Tissue 2 239133980 C T AC016757.3 p.G99R 0 69 0.162162 74WCM131_Z2_1 Tissue 2 239134138 A C AC016757.3 p.V46G 0 86 0.161616 99WCM131_Z2_1 Tissue 2 240036889 C A HDAC4 p.G546W 0 110 0.138298 94WCM131_Z2_1 Tissue 2 240702099 G A AC093802.1 p.R50H 0 72 0.147059 68WCM131_Z2_1 Tissue 2 241872597 A G AC104809.3 p.Q328R 0 48 0.145833 48WCM131_Z2_1 Tissue 2 24222717 A T UBXN2A p.R254* 0 92 0.128571 70WCM131_Z2_1 Tissue 2 242606080 G A ATG4B p.V187I 0 49 0.128205 39WCM131_Z2_1 Tissue 2 25013348 T G PTRHD1 p.I119L 0 212 0.192513 187WCM131_Z2_1 Tissue 2 31609376 G A XDH p.R233C 0 88 0.184466 103WCM131_Z2_1 Tissue 2 32733203 G A BIRC6 p.R3286Q 0 124 0.230216 139WCM131_Z2_1 Tissue 2 40392088 T A SLC8A1 p.E692V 0 96 0.1875 80WCM131_Z2_1 Tissue 2 73491590 C T FBXO41 p.R541H 0 74 0.142857 49WCM131_Z2_1 Tissue 2 79254251 G T REG3G p.S96I 0 128 0.144068 118WCM131_Z2_1 Tissue 3 112732817 A C C3orf17 p.F108L 0 38 0.1875 48WCM131_Z2_1 Tissue 3 130098272 A G COL6A5 p.I227V 0 184 0.152174 184WCM131_Z2_1 Tissue 3 132242405 G A DNAJC13 p.V1970M 0 66 0.089888 89WCM131_Z2_1 Tissue 3 13413399 C T NUP210 p.S574N 0 37 0.066667 60WCM131_Z2_1 Tissue 3 149485521 T C ANKUB1 p.M310V 0 138 0.151079 139WCM131_Z2_1 Tissue 3 36899394 C T TRANK1 p.V563M 0 167 0.172932 133WCM131_Z2_1 Tissue 4 100570681 T A RP11- p.M1709L 0 157 0.164179 134WCM131_Z2_1 Tissue 766F14.2 4 100571001 T C RP11- p.Q1602R 0 1290.145631 103 WCM131_Z2_1 Tissue 766F14.2 4 100575711 C T RP11- p.R32Q 0159 0.144509 173 WCM131_Z2_1 Tissue 766F14.2 4 114458513 G T CAMK2Dp.D167E 0 185 0.168831 154 WCM131_Z2_1 Tissue 4 126238008 A T FAT4p.S148C 0 54 0.093023 43 WCM131_Z2_1 Tissue 4 126371478 A G FAT4p.S3103G 0 193 0.118012 161 WCM131_Z2_1 Tissue 4 135121066 T G PABPC4Lp.H370P 0 141 0.4 120 WCM131_Z2_1 Tissue 4 135121601 C T PABPC4L p.V192I0 58 0.301205 83 WCM131_Z2_1 Tissue 4 152203391 G A PRSS48 p.V103I 0 1110.346154 104 WCM131_Z2_1 Tissue 4 154557562 C T KIAA0922 p.T1555M 0 800.168317 101 WCM131_Z2_1 Tissue 4 15516409 C A CC2D2A p.A266E 0 790.236364 55 WCM131_Z2_1 Tissue 4 17690072 T C FAM184B p.Q524R 0 1690.119403 134 WCM131_Z2_1 Tissue 4 20619178 C T SLIT2 p.A1418V 0.005155194 0.193182 176 WCM131_Z2_1 Tissue 4 3263138 G A MSANTD1 p.R282Q 0 1110.116667 60 WCM131_Z2_1 Tissue 4 527677 T C PIGG p.I881T 0 237 0.189076238 WCM131_Z2_1 Tissue 4 54967809 C A GSX2 p.T212K 0 93 0.19403 67WCM131_Z2_1 Tissue 4 70391429 G A UGT2B4 p.H7Y 0 92 0.236559 93WCM131_Z2_1 Tissue 4 77192868 G A FAM47E p.E273K 0 211 0.388889 180WCM131_Z2_1 Tissue 4 79291115 A T FRAS1 p.D949V 0 105 0.190083 121WCM131_Z2_1 Tissue 5 102894627 A G NUDT12 p.L250P 0 60 0.061224 49WCM131_Z2_1 Tissue 5 112175240 G C APC p.E1317Q 0 79 0.192308 52WCM131_Z2_1 Tissue 5 127744469 G A FBN2 p.P326S 0 105 0.194175 103WCM131_Z2_1 Tissue 5 135258105 G A LECT2 p.P103L 0 188 0.413333 150WCM131_Z2_1 Tissue 5 138730407 C T PROB1 p.G122S 0 72 0.15942 69WCM131_Z2_1 Tissue 5 140047844 G A WDR55 p.E73K 0 96 0.106667 75WCM131_Z2_1 Tissue 5 140581704 A T PCDHB11 p.N786I 0 87 0.15 100WCM131_Z2_1 Tissue 5 141019693 T A RELL2 p.V237E 0 90 0.078947 76WCM131_Z2_1 Tissue 5 141019695 C T RELL2 p.Q238* 0 105 0.1 80WCM131_Z2_1 Tissue 5 171201499 G C CTB-78H18.1 p.G97A 0 93 0.072289 83WCM131_Z2_1 Tissue 5 23976115 G A C5orf17 p.V84I 0.009852 203 0.365854123 WCM131_Z2_1 Tissue 5 32088073 A G PDZD2 p.I1507V 0 80 0.081395 86WCM131_Z2_1 Tissue 5 36052004 A T UGT3A2 p.F93L 0 114 0.211538 104WCM131_Z2_1 Tissue 5 43245944 G A NIM1 p.D23N 0 108 0.165138 109WCM131_Z2_1 Tissue 5 55237432 A C IL6ST p.D745E 0 74 0.234043 94WCM131_Z2_1 Tissue 5 60840045 T A ZSWIM6 p.H1183Q 0 168 0.152047 171WCM131_Z2_1 Tissue 5 71494208 G A MAP1B p.V1676M 0 92 0.13 100WCM131_Z2_1 Tissue 5 86703952 A T CCNH p.S122R 0 59 0.181818 44WCM131_Z2_1 Tissue 5 93753017 C T KIAA0825 p.A851T 0 149 0.203593 167WCM131_Z2_1 Tissue 5 93987532 C A ANKRD32 p.S288R 0 145 0.137097 124WCM131_Z2_1 Tissue 6 100390957 C T MCHR2 p.R152Q 0 116 0.197368 76WCM131_Z2_1 Tissue 6 111912730 C A TRAF3IP2 p.R196L 0 37 0.075 40WCM131_Z2_1 Tissue 6 119137147 T C MCM9 p.T758A 0 93 0.261364 88WCM131_Z2_1 Tissue 6 135323972 C T HBS1L p.V147I 0 94 0.072289 83WCM131_Z2_1 Tissue 6 13711281 G C RANBP9 p.R153G 0 130 0.12 125WCM131_Z2_1 Tissue 6 159420722 G T RSPH3 p.P96H 0 38 0.138889 36WCM131_Z2_1 Tissue 6 166308065 G C SDIM1 p.S30C 0 101 0.148387 155WCM131_Z2_1 Tissue 6 167356509 G C RNASET2 p.F110L 0 32 0.162162 37WCM131_Z2_1 Tissue 6 27278020 C A POM121L2 p.G644C 0 153 0.218978 137WCM131_Z2_1 Tissue 6 27279632 C A POM121L2 p.W106C 0 192 0.108108 148WCM131_Z2_1 Tissue 6 28297279 C T ZSCAN31 p.R61Q 0 135 0.253846 130WCM131_Z2_1 Tissue 6 28964347 C T ZNF311 p.M144I 0 41 0.113208 53WCM131_Z2_1 Tissue 6 30139794 C T TRIM15 p.Q356* 0 67 0.214286 70WCM131_Z2_1 Tissue 6 43336946 G T ZNF318 p.P53Q 0 46 0.130435 46WCM131_Z2_1 Tissue 6 46977400 C T GPR110 p.V591M 0 82 0.2625 80WCM131_Z2_1 Tissue 6 49479750 T C GLYATL3 p.M16T 0 109 0.130435 92WCM131_Z2_1 Tissue 6 49489397 C A GLYATL3 p.A118D 0 93 0.136364 66WCM131_Z2_1 Tissue 6 52141987 G A MCM3 p.S348F 0 174 0.240506 158WCM131_Z2_1 Tissue 6 5999364 C T NRN1 p.D92N 0 112 0.15 120 WCM131_Z2_1Tissue 6 65300143 G C EYS p.L1873V 0 74 0.107143 56 WCM131_Z2_1 Tissue 665301217 G A EYS p.R1515W 0 126 0.172414 58 WCM131_Z2_1 Tissue 665301408 A G EYS p.I1451T 0 98 0.116883 77 WCM131_Z2_1 Tissue 6 65301679T C EYS p.I1361V 0 32 0.129032 31 WCM131_Z2_1 Tissue 6 74183172 C T MTO1p.T207M 0 110 0.126437 87 WCM131_Z2_1 Tissue 6 84896142 C T KIAA1009p.E437K 0 67 0.089552 67 WCM131_Z2_1 Tissue 6 97246455 T C GPR63 p.M385V0 75 0.130952 84 WCM131_Z2_1 Tissue 7 100636383 G A MUC12 p.V990I 0 1130.138614 101 WCM131_Z2_1 Tissue 7 100678784 G T MUC17 p.D1363Y 0 600.12069 58 WCM131_Z2_1 Tissue 7 100678785 A T MUC17 p.D1363V 0 590.12069 58 WCM131_Z2_1 Tissue 7 116340262 A G MET p.N375S 0 72 0.23809563 WCM131_Z2_1 Tissue 7 141838362 C G RP11- p.F327L 0 81 0.268293 82WCM131_Z2_1 Tissue 1220K2.2 7 144094613 G T NOBOX p.P599H 0.006098 1640.205298 151 WCM131_Z2_1 Tissue 7 14622701 C T DGKB p.V500M 0 350.069767 43 WCM131_Z2_1 Tissue 7 150932381 T G CHPF2 p.F171V 0 1370.128205 78 WCM131_Z2_1 Tissue 7 150932382 T C CHPF2 p.F171S 0 1370.128205 78 WCM131_Z2_1 Tissue 7 150934469 C T CHPF2 p.R341W 0 850.21978 91 WCM131_Z2_1 Tissue 7 31692357 C T CCDC129 p.P1017S 0 1220.210526 114 WCM131_Z2_1 Tissue 7 45122324 C A NACAD p.C1152F 0 370.151515 33 WCM131_Z2_1 Tissue 7 45122464 A C NACAD p.D1105E 0 660.222222 72 WCM131_Z2_1 Tissue 7 45124286 A G NACAD p.V498A 0 1210.222222 99 WCM131_Z2_1 Tissue 7 48685105 C G ABCA13 p.I5058M 0 1780.162162 111 WCM131_Z2_1 Tissue 7 86469006 G A GRM3 p.V726I 0 620.090909 33 WCM131_Z2_1 Tissue 7 87053289 G A ABCB4 p.T715I 0 570.254545 55 WCM131_Z2_1 Tissue 7 91779971 T G LRRD1 p.I719L 0 49 0.14 50WCM131_Z2_1 Tissue 7 99145678 C G FAM200A p.R118P 0 58 0.264151 53WCM131_Z2_1 Tissue 8 105511570 C G LRP12 p.K150N 0 208 0.130631 222WCM131_Z2_1 Tissue 8 119945239 G T TNFRSF11B p.R111S 0 121 0.151899 79WCM131_Z2_1 Tissue 8 120103453 A G COLEC10 p.K96E 0 96 0.147287 129WCM131_Z2_1 Tissue 8 126194399 A G NSMCE2 p.K107E 0 40 0.196721 61WCM131_Z2_1 Tissue 8 145141025 G T GPAA1 p.K621N 0 87 0.251908 131WCM131_Z2_1 Tissue 8 17170887 T A MTMR7 p.M297L 0 107 0.109375 128WCM131_Z2_1 Tissue 8 23147564 G A R3HCC1 p.R185K 0 143 0.103226 155WCM131_Z2_1 Tissue 8 23150878 T G R3HCC1 p.L403R 0 142 0.129496 139WCM131_Z2_1 Tissue 8 70476314 A G SULF1 p.Q35R 0 54 0.138889 36WCM131_Z2_1 Tissue 9 100405634 G A NCBP1 p.V125M 0 94 0.164835 91WCM131_Z2_1 Tissue 9 123287277 G A CDK5RAP2 p.T360I 0 249 0.142857 252WCM131_Z2_1 Tissue 9 125377540 C T OR1Q1 p.P175L 0 167 0.147826 115WCM131_Z2_1 Tissue 9 133305911 G A HMCN2 p.R566H 0 301 0.147766 291WCM131_Z2_1 Tissue 9 134314416 A G PRRC2B p.Q146R 0 78 0.227273 88WCM131_Z2_1 Tissue 9 137801702 G A FCN1 p.A308V 0 110 0.105691 123WCM131_Z2_1 Tissue 9 18706950 G A ADAMTSL1 p.E594K 0 167 0.202899 138WCM131_Z2_1 Tissue 9 34978079 G A KIAA1045 p.A392T 0 52 0.25 72WCM131_Z2_1 Tissue 9 5358304 T C PLGRKT p.M127V 0 61 0.1875 64WCM131_Z2_1 Tissue 9 80043927 A C GNA14 p.S207A 0 32 0.176471 34WCM131_Z2_1 Tissue 9 96312954 A G FAM120A p.D752G 0 118 0.185484 124WCM131_Z2_1 Tissue X 128924982 C A SASH3 p.P123T 0 39 0.157895 57WCM131_Z2_1 Tissue X 152772527 A G BGN p.I265V 0 42 0.484848 33WCM131_Z2_1 Tissue X 19398315 C T MAP3K15 p.G838S 0 118 0.364706 85WCM131_Z2_1 Tissue X 27766045 A G DCAF8L2 p.T345A 0 74 0.3625 80WCM131_Z2_1 Tissue X 65253352 C T VSIG4 p.V126M 0 104 0.208791 91WCM131_Z2_1 Tissue X 8501076 C T KAL1 p.R668H 0 47 0.0625 48 WCM131_Z2_1Tissue 15 43712787 T C TP53BP1 p.D1461G 0 31 0.113208 53 WCM139 Plasma 1110022072 G T SYPL2 p.G241* 0 86 0.308824 68 WCM139_Z3_1 Tissue 11102565721 C G MMP27 p.R337T 0 160 0.363322 289 WCM139_Z3_1 Tissue 11119149311 G A CBL p.G440D 0 106 0.368932 103 WCM139_Z3_1 Tissue 1117632357 C T OTOG p.A1849V 0 45 0.468085 47 WCM139_Z3_1 Tissue 1158906898 A G PYHIN1 p.I66M 0 56 0.347222 72 WCM139_Z3_1 Tissue 116199609 C T SPEN p.R128C 0 106 0.377551 98 WCM139_Z3_1 Tissue 1213906693 T G GRIN2B p.I190L 0 43 0.373134 67 WCM139_Z3_1 Tissue 1223988456 G A TP53BP2 p.P428S 0 92 0.247863 117 WCM139_Z3_1 Tissue 1228459740 A T CCDC91 p.K111N 0 53 0.296296 54 WCM139_Z3_1 Tissue 122927541 C G EPHA8 p.R897G 0 76 0.353535 99 WCM139_Z3_1 Tissue 1 2435432G A PLCH2 p.A1011T 0 69 0.333333 90 WCM139_Z3_1 Tissue 12 50284851 G TFAIM2 p.P161T 0 80 0.394366 71 WCM139_Z3_1 Tissue 1 35370585 C T DLGAP3p.D134N 0 184 0.331776 214 WCM139_Z3_1 Tissue 14 20216486 G T OR4Q3p.K300N 0 79 0.122222 90 WCM139_Z3_1 Tissue 14 20825801 G A PARP2p.G533R 0 40 0.319149 47 WCM139_Z3_1 Tissue 16 1420262 G A UNKL p.P482L0 79 0.058824 68 WCM139_Z3_1 Tissue 16 4475898 T A DNAJA3 p.S6T 0 1310.414634 123 WCM139_Z3_1 Tissue 16 68338031 T G SLC7A6OS p.K192N 0 1380.385057 174 WCM139_Z3_1 Tissue 17 37627173 C G CDK12 p.S363* 0 960.550459 109 WCM139_Z3_1 Tissue 17 37676268 G A CDK12 p.R1008Q 0 1040.386598 194 WCM139_Z3_1 Tissue 17 53848473 A G PCTP p.Y89C 0 700.432432 74 WCM139_Z3_1 Tissue 17 65919104 G C BPTF p.E2028D 0 2120.335878 131 WCM139_Z3_1 Tissue 17 74383123 G A SPHK1 p.R204H 0 420.315068 73 WCM139_Z3_1 Tissue 18 74154470 T C ZNF516 p.S181G 0 840.228571 70 WCM139_Z3_1 Tissue 19 2834054 A G ZNF554 p.E274G 0 760.432432 74 WCM139_Z3_1 Tissue 19 36223914 G A KMT2B p.S2155N 0 1190.366667 120 WCM139_Z3_1 Tissue 20 48522659 G A SPATA2 p.R354W 0 770.308511 94 WCM139_Z3_1 Tissue 21 30380741 T A RWDD2B p.N90I 0 910.254386 114 WCM139_Z3_1 Tissue 2 210769634 T C UNC80 p.L1510P 0 490.789474 38 WCM139_Z3_1 Tissue 2 73829384 G C ALMS1 p.V4062L 0 1730.323308 133 WCM139_Z3_1 Tissue 3 180364927 C A CCDC39 p.K489N 0 930.072289 83 WCM139_Z3_1 Tissue 3 195486003 T A MUC4 p.E757V 0 208 0.2443307 WCM139_Z3_1 Tissue 3 33626356 C T CLASP2 p.V710M 0 62 0.276596 47WCM139_Z3_1 Tissue 3 55043418 C G CACNA2D3 p.F941L 0 117 0.366412 131WCM139_Z3_1 Tissue 5 96322326 C G LNPEP p.F361L 0 68 0.267857 56WCM139_Z3_1 Tissue 6 36930927 C T PI16 p.T270M 0 53 0.247312 93WCM139_Z3_1 Tissue 7 114619628 G C MDFIC p.K95N 0 289 0.290698 344WCM139_Z3_1 Tissue 8 88885353 G T DCAF4L2 p.Q283K 0 80 0.417722 79WCM139_Z3_1 Tissue 8 97258618 G A MTERFD1 p.P248S 0 40 0.116883 77WCM139_Z3_1 Tissue 9 100675731 G A C9orf156 p.R121C 0 63 0.347826 69WCM139_Z3_1 Tissue X 108628499 G A GUCY2F p.A990V 0 44 0.818182 88WCM139_Z3_1 Tissue 18 2544212 G A METTL4 p.H419Y 0 46 0.090909 99 WCM142Plasma 19 55568026 A G RDH13 p.I112T 0 35 0.163265 98 WCM142 Plasma 7138793787 G T ZC3HAV1 p.N97K 0 36 0.073171 41 WCM142 Plasma 7 31378621 GA NEUROD6 p.R88* 0 38 0.139785 93 WCM142 Plasma 10 115535591 T A PLEKHS1p.Y333N 0 86 0.285714 56 WCM14-TP1 Plasma 10 28884782 C T WAC p.T244M 051 0.157895 38 WCM14-TP1 Plasma 10 89692871 G T PTEN p.V119F 0 730.560976 41 WCM14-TP1 Plasma 1 115469139 A T SYCP1 p.K627N 0 1070.585185 135 WCM14-TP1 Plasma 1 197019880 G C F13B p.S562C 0 72 0.16304392 WCM14-TP1 Plasma 1 197020006 G A F13B p.S520F 0 33 0.1 40 WCM14-TP1Plasma 1 241797444 T A CHML p.E542V 0 77 0.323529 68 WCM14-TP1 Plasma 124411081 G A MYOM3 p.T616I 0 73 0.568965 58 WCM14-TP1 Plasma 15101602818 C T LRRK1 p.P1613S 0 69 0.171429 35 WCM14-TP1 Plasma 1671674330 G A MARVELD3 p.M211I 0 109 0.452381 42 WCM14-TP1 Plasma 1690130121 G A PRDM7 p.T136M 0 76 0.348485 66 WCM14-TP1 Plasma 19 44890819G A ZNF285 p.H530Y 0 71 0.194444 72 WCM14-TP1 Plasma 20 45867667 C TZMYND8 p.V814M 0 110 0.1875 48 WCM14-TP1 Plasma 2 206036978 G C PARD3Bp.G555A 0 52 0.192308 52 WCM14-TP1 Plasma 22 41318352 G T XPNPEP3p.Q357H 0 79 0.085714 35 WCM14-TP1 Plasma 3 185332407 G A SENP2 p.R330H0 83 0.193548 62 WCM14-TP1 Plasma 3 89259166 C G EPHA3 p.R104G 0 560.225 40 WCM14-TP1 Plasma 4 46737038 C A COX7B2 p.A58S 0 84 0.186441 59WCM14-TP1 Plasma 5 150075168 G A RBM22 p.R216W 0 79 0.234375 64WCM14-TP1 Plasma 6 29012859 C T OR2W1 p.A32T 0 69 0.148649 74 WCM14-TP1Plasma 6 70490440 C T LMBRD1 p.A85T 0 80 0.230769 65 WCM14-TP1 Plasma 7111503433 T A DOCK4 p.N823I 0 38 0.536585 41 WCM14-TP1 Plasma 7 92244482T C CDK6 p.Q318R 0 47 0.108108 37 WCM14-TP1 Plasma 8 85717033 G T RALYLp.V121F 0 172 0.502825 177 WCM14-TP1 Plasma 10 115535591 T A PLEKHS1p.Y333N 0 86 0.22973 74 WCM14-TP2 Plasma 10 134664698 G A TTC40 p.Q1896*0 61 0.078947 38 WCM14-TP2 Plasma 10 28884782 C T WAC p.T244M 0 510.189189 74 WCM14-TP2 Plasma 10 89692871 G T PTEN p.V119F 0 73 0.4489849 WCM14-TP2 Plasma 1 115469139 A T SYCP1 p.K627N 0 107 0.46729 107WCM14-TP2 Plasma 11 5537603 G T UBQLNL p.D23E 0 40 0.130435 46 WCM14-TP2Plasma 11 62782337 C T SLC22A8 p.A32T 0 41 0.068966 58 WCM14-TP2 Plasma1 197019880 G C F13B p.S562C 0 72 0.154639 97 WCM14-TP2 Plasma 1197020006 G A F13B p.S520F 0 33 0.113636 44 WCM14-TP2 Plasma 1 197026575G T F13B p.P276T 0 52 0.12 100 WCM14-TP2 Plasma 1 202287490 C T LGR6p.R687* 0 46 0.205882 34 WCM14-TP2 Plasma 1 241797444 T A CHML p.E542V 077 0.426829 82 WCM14-TP2 Plasma 1 24411081 G A MYOM3 p.T616I 0 730.394737 76 WCM14-TP2 Plasma 15 101602818 C T LRRK1 p.P1613S 0 690.292683 41 WCM14-TP2 Plasma 15 50866653 T A TRPM7 p.Y1709F 0 370.096774 31 WCM14-TP2 Plasma 16 46962846 G T GPT2 p.K503N 0 41 0.09090933 WCM14-TP2 Plasma 16 71674330 G A MARVELD3 p.M211I 0 109 0.268293 82WCM14-TP2 Plasma 16 90130121 G A PRDM7 p.T136M 0 76 0.253333 75WCM14-TP2 Plasma 17 43473626 C T ARHGAP27 p.R733H 0 72 0.069767 43WCM14-TP2 Plasma 17 71418463 C T SDK2 p.D670N 0 47 0.1875 32 WCM14-TP2Plasma 18 14748612 A T ANKRD30B p.N65I 0 58 0.21875 32 WCM14-TP2 Plasma1 8418696 C T RERE p.R1300H 0 89 0.26087 46 WCM14-TP2 Plasma 18 60017090G T TNFRSF11A p.C68F 0 101 0.054348 92 WCM14-TP2 Plasma 19 44890819 G AZNF285 p.H530Y 0 71 0.21875 96 WCM14-TP2 Plasma 19 50045998 G A RCN3p.D290N 0 59 0.071429 42 WCM14-TP2 Plasma 20 2572966 G A TMC2 p.G282D 052 0.069767 43 WCM14-TP2 Plasma 20 33971877 G T UQCC1 p.D63E 0 590.061224 49 WCM14-TP2 Plasma 20 35173396 G A MYL9 p.A37T 0 55 0.07692339 WCM14-TP2 Plasma 20 45867667 C T ZMYND8 p.V814M 0 110 0.197368 76WCM14-TP2 Plasma 2 206036978 G C PARD3B p.G555A 0 52 0.183099 71WCM14-TP2 Plasma 3 185332407 G A SENP2 p.R330H 0 83 0.162162 74WCM14-TP2 Plasma 3 89259166 C G EPHA3 p.R104G 0 56 0.113636 44 WCM14-TP2Plasma 4 46737038 C A COX7B2 p.A58S 0 84 0.15493 71 WCM14-TP2 Plasma 5140793488 C T PCDHGA10 p.P249L 0 41 0.170732 41 WCM14-TP2 Plasma 5150075168 G A RBM22 p.R216W 0 79 0.202703 74 WCM14-TP2 Plasma 6 29012859C T OR2W1 p.A32T 0 69 0.209877 81 WCM14-TP2 Plasma 6 47681812 G T GPR115p.R277S 0 39 0.411765 34 WCM14-TP2 Plasma 6 70490440 C T LMBRD1 p.A85T 080 0.168675 83 WCM14-TP2 Plasma 7 111503433 T A DOCK4 p.N823I 0 380.451613 62 WCM14-TP2 Plasma 7 92244482 T C CDK6 p.Q318R 0 47 0.13461552 WCM14-TP2 Plasma 8 145745719 G A LRRC14 p.V143I 0 63 0.076923 39WCM14-TP2 Plasma 8 85717033 G T RALYL p.V121F 0 172 0.425926 162WCM14-TP2 Plasma X 100749082 G C ARMCX4 p.G1836R 0 41 0.205882 34WCM14-TP2 Plasma X 144904892 G T SLITRK2 p.V317L 0 54 0.483871 31WCM14-TP2 Plasma X 37265509 A G PRRG1 p.R3G 0 46 0.064516 62 WCM14-TP2Plasma 10 115535591 T A PLEKHS1 p.Y333N 0 86 0.19802 101 WCM14-TP3Plasma 10 28884782 C T WAC p.T244M 0 51 0.076923 65 WCM14-TP3 Plasma 1089692871 G T PTEN p.V119F 0 73 0.327273 55 WCM14-TP3 Plasma 1 166819116C A POGK p.R434S 0 57 0.066667 45 WCM14-TP3 Plasma 1 197019880 G C F13Bp.S562C 0 72 0.075472 106 WCM14-TP3 Plasma 1 197020006 G A F13B p.S520F0 33 0.071429 56 WCM14-TP3 Plasma 1 197026575 G T F13B p.P276T 0 520.09434 106 WCM14-TP3 Plasma 1 241797444 T A CHML p.E542V 0 77 0.28972107 WCM14-TP3 Plasma 1 24411081 G A MYOM3 p.T616I 0 73 0.259259 81WCM14-TP3 Plasma 1 29475181 C T SRSF4 p.R409H 0 34 0.083333 36 WCM14-TP3Plasma 15 101602818 C T LRRK1 p.P1613S 0 69 0.174603 63 WCM14-TP3 Plasma15 65425308 T C PDCD7 p.E271G 0 76 0.151515 33 WCM14-TP3 Plasma 1671674330 G A MARVELD3 p.M211I 0 109 0.190476 84 WCM14-TP3 Plasma 1690130121 G A PRDM7 p.T136M 0 76 0.282353 85 WCM14-TP3 Plasma 17 71418463C T SDK2 p.D670N 0 47 0.15625 32 WCM14-TP3 Plasma 18 14748612 A TANKRD30B p.N65I 0 58 0.15 40 WCM14-TP3 Plasma 1 8418696 C T REREp.R1300H 0 89 0.159091 44 WCM14-TP3 Plasma 19 44890819 G A ZNF285p.H530Y 0 71 0.065421 107 WCM14-TP3 Plasma 20 45867667 C T ZMYND8p.V814M 0 110 0.111111 90 WCM14-TP3 Plasma 3 185332407 G A SENP2 p.R330H0 83 0.15534 103 WCM14-TP3 Plasma 3 89259166 C G EPHA3 p.R104G 0 560.112903 62 WCM14-TP3 Plasma 4 46737038 C A COX7B2 p.A58S 0 84 0.20481983 WCM14-TP3 Plasma 5 140793488 C T PCDHGA10 p.P249L 0 41 0.130435 46WCM14-TP3 Plasma 5 150075168 G A RBM22 p.R216W 0 79 0.11236 89 WCM14-TP3Plasma 6 29012859 C T OR2W1 p.A32T 0 69 0.139785 93 WCM14-TP3 Plasma 634100922 G T GRM4 p.Q118K 0 42 0.081081 37 WCM14-TP3 Plasma 6 47681812 GT GPR115 p.R277S 0 39 0.323529 34 WCM14-TP3 Plasma 6 70490440 C T LMBRD1p.A85T 0 80 0.144231 104 WCM14-TP3 Plasma 7 111503433 T A DOCK4 p.N823I0 38 0.327869 61 WCM14-TP3 Plasma X 49075190 G T CACNA1F p.T924K 0 460.071429 56 WCM14-TP3 Plasma 10 115535591 T A PLEKHS1 p.Y333N 0 860.34375 96 WCM14-TP4 Plasma 10 28884782 C T WAC p.T244M 0 51 0.180328 61WCM14-TP4 Plasma 10 89692871 G T PTEN p.V119F 0 73 0.682927 41 WCM14-TP4Plasma 1 115469139 A T SYCP1 p.K627N 0 107 0.469027 113 WCM14-TP4 Plasma11 40137316 C T LRRC4C p.R176Q 0 40 0.098039 51 WCM14-TP4 Plasma 1197019880 G C F13B p.S562C 0 72 0.163636 110 WCM14-TP4 Plasma 1197026575 G T F13B p.P276T 0 52 0.107527 93 WCM14-TP4 Plasma 1 202287490C T LGR6 p.R687* 0 46 0.142857 49 WCM14-TP4 Plasma 1 241797444 T A CHMLp.E542V 0 77 0.488372 86 WCM14-TP4 Plasma 1 24411081 G A MYOM3 p.T616I 073 0.561798 89 WCM14-TP4 Plasma 15 101602818 C T LRRK1 p.P1613S 0 690.469697 66 WCM14-TP4 Plasma 16 71674330 G A MARVELD3 p.M211I 0 1090.455556 90 WCM14-TP4 Plasma 16 76587357 G A RP11- p.G15D 0 49 0.08 50WCM14-TP4 Plasma 58C22.1 16 90130121 G A PRDM7 p.T136M 0 76 0.246914 81WCM14-TP4 Plasma 17 71418463 C T SDK2 p.D670N 0 47 0.16 50 WCM14-TP4Plasma 18 14748612 A T ANKRD30B p.N65I 0 58 0.179487 39 WCM14-TP4 Plasma1 8418696 C T RERE p.R1300H 0 89 0.15873 63 WCM14-TP4 Plasma 19 38573514G A SIPA1L3 p.E437K 0 36 0.472222 36 WCM14-TP4 Plasma 19 44890819 G AZNF285 p.H530Y 0 71 0.206186 97 WCM14-TP4 Plasma 20 45867667 C T ZMYND8p.V814M 0 110 0.323232 99 WCM14-TP4 Plasma 2 206036978 G C PARD3Bp.G555A 0 52 0.202899 69 WCM14-TP4 Plasma 3 185332407 G A SENP2 p.R330H0 83 0.137255 102 WCM14-TP4 Plasma 3 89259166 C G EPHA3 p.R104G 0 560.195652 46 WCM14-TP4 Plasma 4 46737038 C A COX7B2 p.A58S 0 84 0.14285770 WCM14-TP4 Plasma 5 140712178 G A PCDHGA1 p.V643M 0 45 0.272727 33WCM14-TP4 Plasma 5 140793488 C T PCDHGA10 p.P249L 0 41 0.095238 42WCM14-TP4 Plasma 5 150075168 G A RBM22 p.R216W 0 79 0.157895 76WCM14-TP4 Plasma 6 29012859 C T OR2W1 p.A32T 0 69 0.214286 98 WCM14-TP4Plasma 6 47681812 G T GPR115 p.R277S 0 39 0.487805 41 WCM14-TP4 Plasma 670490440 C T LMBRD1 p.A85T 0 80 0.277108 83 WCM14-TP4 Plasma 7 111503433T A DOCK4 p.N823I 0 38 0.571429 63 WCM14-TP4 Plasma 7 92244482 T C CDK6p.Q318R 0 47 0.103448 58 WCM14-TP4 Plasma 7 98649843 G C SMURF 1 p.L236V0 68 0.069307 101 WCM14-TP4 Plasma 8 85717033 G T RALYL p.V121F 0 1720.666667 180 WCM14-TP4 Plasma X 37265509 A G PRRG1 p.R3G 0 46 0.1 80WCM14-TP4 Plasma 10 115535591 T A PLEKHS1 p.Y333N 0 87 0.186667 75WCM14_x1_1 Tissue 10 89692871 G T PTEN p.V119F 0 117 0.49505 101WCM14_x1_1 Tissue 1 115469139 A T SYCP1 p.K627N 0 116 0.348485 66WCM14_x1_1 Tissue 11 40137316 C T LRRC4C p.R176Q 0 143 0.171875 128WCM14_x1_1 Tissue 11 5537603 G T UBQLNL p.D23E 0 122 0.310078 129WCM14_x1_1 Tissue 1 241797444 T A CHML p.E542V 0 177 0.283133 166WCM14_x1_1 Tissue 1 24411081 G A MYOM3 p.T616I 0 103 0.454545 66WCM14_x1_1 Tissue 15 101602818 C T LRRK1 p.P1613S 0 180 0.269608 204WCM14_x1_1 Tissue 16 71674330 G A MARVELD3 p.M211I 0 70 0.402778 72WCM14_x1_1 Tissue 17 71418463 C T SDK2 p.D670N 0 185 0.169697 165WCM14_x1_1 Tissue 18 14748612 A T ANKRD30B p.N65I 0 118 0.204918 122WCM14_x1_1 Tissue 1 8418696 C T RERE p.R1300H 0 133 0.169118 136WCM14_x1_1 Tissue 19 38573514 G A SIPA1L3 p.E437K 0 199 0.274611 193WCM14_x1_1 Tissue 19 50251660 G A TSKS p.R156W 0 95 0.067961 103WCM14_x1_1 Tissue 20 45867667 C T ZMYND8 p.V814M 0 155 0.097744 133WCM14_x1_1 Tissue 21 33036109 A T SOD1 p.N27Y 0 109 0.058824 102WCM14_x1_1 Tissue 2 202899559 C A FZD7 p.N63K 0 98 0.365854 82WCM14_x1_1 Tissue 2 206036978 G C PARD3B p.G555A 0 126 0.064935 154WCM14_x1_1 Tissue 3 185332407 G A SENP2 p.R330H 0 63 0.060241 83WCM14_x1_1 Tissue 3 49689777 C T BSN p.R930C 0 165 0.092437 119WCM14_x1_1 Tissue 4 46737038 C A COX7B2 p.A58S 0 154 0.145455 110WCM14_x1_1 Tissue 5 140712178 G A PCDHGA1 p.V643M 0 34 0.193548 31WCM14_x1_1 Tissue 5 154179454 G T LARP1 p.R446L 0 167 0.6 120 WCM14_x1_1Tissue 6 110567307 G A METTL24 p.R315W 0 81 0.134146 82 WCM14_x1_1Tissue 6 47681812 G T GPR115 p.R277S 0 111 0.431193 109 WCM14_x1_1Tissue 6 70490440 C T LMBRD1 p.A85T 0 56 0.326531 49 WCM14_x1_1 Tissue 7111503433 T A DOCK4 p.N823I 0 165 0.451923 208 WCM14_x1_1 Tissue 885717033 G T RALYL p.V121F 0 59 0.59375 64 WCM14_x1_1 Tissue 9 116132001C T BSPRY p.A263V 0 348 0.441065 263 WCM14_x1_1 Tissue 9 140151472 T CNELFB p.F188S 0 79 0.192308 52 WCM14_x1_1 Tissue 10 122626092 G T WDR11p.V336F 0 62 0.071429 42 WCM14_Z11_1 Tissue 1 110085766 C T GPR61 p.S41L0 43 0.06383 47 WCM14_Z11_1 Tissue 11 117859166 C A IL10RA p.T46K 0 450.069767 43 WCM14_Z11_1 Tissue 11 126144826 G C FOXRED1 p.E181Q 0 1490.093264 193 WCM14_Z11_1 Tissue 1 11579538 G T PTCHD2 p.L672F 0 360.06383 47 WCM14_Z11_1 Tissue 11 27395538 C A LGR4 p.G413W 0 152 0.0638394 WCM14_Z11_1 Tissue 11 40137316 C T LRRC4C p.R176Q 0 91 0.173913 69WCM14_Z11_1 Tissue 1 145597026 G T POLR3C p.R367S 0 55 0.065217 46WCM14_Z11_1 Tissue 1 154000038 G T NUP210L p.C1297* 0 71 0.061224 49WCM14_Z11_1 Tissue 11 606594 C A PHRF1 p.A536E 0 51 0.086957 69WCM14_Z11_1 Tissue 1 197020006 G A F13B p.S520F 0 74 0.139535 43WCM14_Z11_1 Tissue 1 197404691 C A CRB1 p.T1233N 0 52 0.075 40WCM14_Z11_1 Tissue 1 202287490 C T LGR6 p.R687* 0 108 0.338912 239WCM14_Z11_1 Tissue 1 211544765 C A TRAF5 p.T351K 0 102 0.088889 45WCM14_Z11_1 Tissue 1 233397844 G T PCNXL2 p.R143S 0 112 0.079208 101WCM14_Z11_1 Tissue 1 241797444 T A CHML p.E542V 0 73 0.653061 49WCM14_Z11_1 Tissue 12 55759028 C A OR6C75 p.T45N 0 45 0.068182 44WCM14_Z11_1 Tissue 1 28793176 C A PHACTR4 p.S240R 0 44 0.085714 35WCM14_Z11_1 Tissue 13 32929413 G C BRCA2 p.E2475Q 0 53 0.096774 31WCM14_Z11_1 Tissue 13 98642748 C A IPO5 p.A209D 0 96 0.139535 43WCM14_Z11_1 Tissue 14 58975407 G T KIAA0586 p.A1420S 0 64 0.066667 45WCM14_Z11_1 Tissue 15 101602818 C T LRRK1 p.P1613S 0 151 0.32381 105WCM14_Z11_1 Tissue 15 28431864 C A HERC2 p.C2895F 0 106 0.054545 55WCM14_Z11_1 Tissue 15 31200443 G T FAN1 p.A453S 0.008 125 0.136364 44WCM14_Z11_1 Tissue 15 42529758 C A TMEM87A p.W247L 0 156 0.068966 87WCM14_Z11_1 Tissue 15 43552639 A G TGM5 p.F50S 0 80 0.133333 45WCM14_Z11_1 Tissue 15 62147094 G C VPS13C p.Y3712* 0 60 0.081081 37WCM14_Z11_1 Tissue 15 89173466 G A AEN p.D307N 0 58 0.0625 48WCM14_Z11_1 Tissue 15 91478812 G T UNC45A p.E30D 0 168 0.061538 130WCM14_Z11_1 Tissue 1 6522098 G A TNFRSF25 p.P294L 0 149 0.050847 177WCM14_Z11_1 Tissue 16 57261319 G T RSPRY1 p.W409C 0 76 0.06 50WCM14_Z11_1 Tissue 16 71674330 G A MARVELD3 p.M211I 0 133 0.495726 117WCM14_Z11_1 Tissue 16 85813414 C A EMC8 p.R178L 0 73 0.055556 72WCM14_Z11_1 Tissue 16 90130121 G A PRDM7 p.T136M 0 58 0.409091 66WCM14_Z11_1 Tissue 17 456623 C T VPS53 p.S595N 0 36 0.096774 31WCM14_Z11_1 Tissue 17 57760498 G T CLTC p.A1306S 0 66 0.090909 33WCM14_Z11_1 Tissue 17 71418463 C T SDK2 p.D670N 0 257 0.182109 313WCM14_Z11_1 Tissue 18 14748612 A T ANKRD30B p.N65I 0 219 0.209184 196WCM14_Z11_1 Tissue 18 25573549 G C CDH2 p.P358R 0 154 0.063492 126WCM14_Z11_1 Tissue 18 32825672 C A ZNF397 p.H335N 0 104 0.12 50WCM14_Z11_1 Tissue 19 1430265 C A DAZAP1 p.P259T 0 33 0.071429 42WCM14_Z11_1 Tissue 19 2271949 G T OAZ1 p.D154Y 0 46 0.073171 41WCM14_Z11_1 Tissue 19 38573514 G A SIPA1L3 p.E437K 0 186 0.220588 204WCM14_Z11_1 Tissue 19 38774407 G T SPINT2 p.E83* 0 98 0.070588 85WCM14_Z11_1 Tissue 1 94342137 G T DNTTIP2 p.Q452K 0 69 0.081081 37WCM14_Z11_1 Tissue 19 44890819 G A ZNF285 p.H530Y 0 74 0.266667 60WCM14_Z11_1 Tissue 19 519070 G A TPGS1 p.E174K 0 80 0.153846 52WCM14_Z11_1 Tissue 19 53454264 C A ZNF816 p.R255I 0 68 0.149254 67WCM14_Z11_1 Tissue 19 58232136 G T ZNF671 p.L440I 0 97 0.097087 103WCM14_Z11_1 Tissue 2 113504004 C A CKAP2L p.G584V 0 74 0.089552 67WCM14_Z11_1 Tissue 2 160879272 G T PLA2R1 p.H400N 0 106 0.073171 82WCM14_Z11_1 Tissue 2 175202132 C A SP9 p.S440Y 0 50 0.065574 61WCM14_Z11_1 Tissue 2 202899559 C A FZD7 p.N63K 0 232 0.300412 243WCM14_Z11_1 Tissue 2 204304825 G T RAPH1 p.L1030I 0 47 0.073171 41WCM14_Z11_1 Tissue 2 206036978 G C PARD3B p.G555A 0 194 0.144279 201WCM14_Z11_1 Tissue 2 210809782 C A UNC80 p.A2287D 0 102 0.125 40WCM14_Z11_1 Tissue 22 30409424 C T MTMR3 p.S466L 0.007092 282 0.074236229 WCM14_Z11_1 Tissue 22 45741402 C A SMC1B p.V1182F 0 38 0.09375 32WCM14_Z11_1 Tissue 3 130714923 C A ATP2C1 p.N698K 0 84 0.061538 65WCM14_Z11_1 Tissue 3 13896130 G A WNT7A p.R157C 0 73 0.083333 108WCM14_Z11_1 Tissue 3 142430743 G T PLS1 p.G595V 0 130 0.054054 74WCM14_Z11_1 Tissue 3 185332407 G A SENP2 p.R330H 0 71 0.19084 131WCM14_Z11_1 Tissue 4 183664431 G T TENM3 p.C1163F 0 65 0.058824 68WCM14_Z11_1 Tissue 4 83745728 G T SEC31A p.L1131I 0 69 0.072464 69WCM14_Z11_1 Tissue 5 133537696 C A PPP2CA p.R110L 0 37 0.078947 38WCM14_Z11_1 Tissue 5 140712178 G A PCDHGA1 p.V643M 0 60 0.279412 68WCM14_Z11_1 Tissue 5 140793488 C T PCDHGA10 p.P249L 0 157 0.253521 142WCM14_Z11_1 Tissue 5 154179454 G T LARP1 p.R446L 0.009524 105 0.770833144 WCM14_Z11_1 Tissue 6 110567307 G A METTL24 p.R315W 0 105 0.216216 74WCM14_Z11_1 Tissue 6 170594410 C A DLL1 p.G322C 0 133 0.074766 107WCM14_Z11_1 Tissue 6 170597383 C T DLL1 p.G205E 0 95 0.102564 78WCM14_Z11_1 Tissue 6 34385294 G T RPS10 p.P163T 0 35 0.09375 32WCM14_Z11_1 Tissue 6 47626738 G T GPR111 p.L39F 0 114 0.088889 90WCM14_Z11_1 Tissue 6 47681812 G T GPR115 p.R277S 0 148 0.456522 92WCM14_Z11_1 Tissue 6 70490440 C T LMBRD1 p.A85T 0 53 0.261905 42WCM14_Z11_1 Tissue 6 72943521 G T RIMS1 p.R575L 0 52 0.193548 31WCM14_Z11_1 Tissue 7 111503433 T A DOCK4 p.N823I 0 179 0.40107 187WCM14_Z11_1 Tissue 7 122811922 G T SLC13A1 p.L89I 0 61 0.055556 54WCM14_Z11_1 Tissue 7 135095294 G T CNOT4 p.N264K 0 58 0.061224 49WCM14_Z11_1 Tissue 7 91870391 C A KRIT1 p.G60C 0 86 0.057471 87WCM14_Z11_1 Tissue 7 92244482 T C CDK6 p.Q318R 0 43 0.197368 76WCM14_Z11_1 Tissue 8 101271292 C T RNF19A p.G670E 0 33 0.056604 53WCM14_Z11_1 Tissue 9 107380437 G T OR13C9 p.H17N 0 45 0.09375 32WCM14_Z11_1 Tissue 9 114986244 G T PTBP3 p.L516I 0 107 0.057143 70WCM14_Z11_1 Tissue 9 130210212 G A RPL12 p.R146C 0 54 0.082192 73WCM14_Z11_1 Tissue 9 140151472 T C NELFB p.F188S 0 180 0.568075 213WCM14_Z11_1 Tissue 9 32481395 G T DDX58 p.D527E 0 58 0.090909 33WCM14_Z11_1 Tissue 9 95148521 G A OGN p.L230F 0 85 0.055556 54WCM14_Z11_1 Tissue X 129267363 G T AIFM1 p.A458D 0 51 0.090909 33WCM14_Z11_1 Tissue X 144904892 G T SLITRK2 p.V317L 0 35 0.454545 44WCM14_Z11_1 Tissue 12 129190265 C T TMEM132C p.R918W 0 33 0.102564 78WCM15 Plasma 12 20833108 C T PDE3A p.S1110L 0 32 0.153846 52 WCM15Plasma 1 233275531 G T PCNXL2 p.Y1196* 0 44 0.141026 78 WCM15 Plasma 1543748441 A C TP53BP1 p.S784A 0 33 0.054795 73 WCM15 Plasma 16 89245906 GA CDH15 p.R42H 0 43 0.1625 80 WCM15 Plasma 17 7576865 A C TP53 p.Y327* 037 0.304762 105 WCM15 Plasma 19 51021577 C T LRRC4B p.G465S 0 360.234375 64 WCM15 Plasma 19 56011593 C T SSC5D p.R706* 0 36 0.123596 89WCM15 Plasma 3 66463436 T C LRIG1 p.D217G 0 31 0.068493 73 WCM15 Plasma7 23213848 T A KLHL7 p.F564L 0 47 0.225352 71 WCM15 Plasma 8 17065500 AG ZDHHC2 p.H210R 0 41 0.126984 63 WCM15 Plasma 9 37745439 C T FRMPD1p.P1137L 0 33 0.075 40 WCM15 Plasma 9 75406899 G A TMC1 p.W441* 0 320.075472 53 WCM15 Plasma 10 28272878 G T ARMC4 p.P238Q 0 48 0.050633 79WCM154 Plasma 11 120291549 C T ARHGEF12 p.S96F 0 44 0.191781 73 WCM154Plasma 11 73796788 G C C2CD3 p.S1262C 0 50 0.189873 79 WCM154 Plasma 1178776035 G A TENM4 p.R81W 0 42 0.351351 74 WCM154 Plasma 1 201982147 G TELF3 p.G224V 0 47 0.202247 89 WCM154 Plasma 1 209803163 C T LAMB3p.E351K 0 61 0.366337 101 WCM154 Plasma 1 214791953 C T CENPF p.Q133* 040 0.354545 110 WCM154 Plasma 14 35565817 T G PPP2R3C p.K262T 0 630.142857 112 WCM154 Plasma 14 38061334 G T FOXA1 p.R219S 0 40 0.28 75WCM154 Plasma 14 96178685 C T TCL1A p.V57I 0 46 0.302083 96 WCM154Plasma 15 75108835 G A LMAN1L p.G133D 0 44 0.060606 66 WCM154 Plasma 2179468729 C T TTN p.V16588M 0 70 0.111111 90 WCM154 Plasma 2 201485940 GT AOX1 p.E658* 0 42 0.054795 73 WCM154 Plasma 22 24896175 C G UPB1p.P69A 0 31 0.319149 47 WCM154 Plasma 2 86707345 C T KDM3A p.S791L 0 330.328767 73 WCM154 Plasma 4 103553339 A G MANBA p.F839L 0 35 0.2 60WCM154 Plasma 4 3318546 G A RGS12 p.D217N 0 45 0.184615 65 WCM154 Plasma4 47954625 G A CNGA1 p.R32* 0 45 0.206186 97 WCM154 Plasma 5 33947380 GA SLC45A2 p.P419L 0 62 0.325 120 WCM154 Plasma 6 138200015 G T TNFAIP3p.C478F 0 46 0.384615 78 WCM154 Plasma 6 36867354 A T C6orf89 p.K45M 046 0.244898 98 WCM154 Plasma 7 100552671 G T MUC3A p.E474D 0 33 0.2 85WCM154 Plasma 7 55902249 C G 14-Sep p.D197H 0 53 0.198113 106 WCM154Plasma 11 73796788 G C C2CD3 p.S1262C 0 331 0.836653 251 WCM154_Z1_1Tissue 1 201982147 G T ELF3 p.G224V 0 193 0.375 256 WCM154_Z1_1 Tissue 1206652374 C T IKBKE p.L361F 0 91 0.316327 98 WCM154_Z1_1 Tissue 1209803163 C T LAMB3 p.E351K 0 102 0.358209 134 WCM154_Z1_1 Tissue 1214791953 C T CENPF p.Q133* 0 65 0.45 80 WCM154_Z1_1 Tissue 1 3548141 GA WRAP73 p.R377C 0 71 0.135135 37 WCM154_Z1_1 Tissue 14 35565817 T GPPP2R3C p.K262T 0 251 0.352273 176 WCM154_Z1_1 Tissue 14 38061334 G TFOXA1 p.R219S 0 32 0.4375 32 WCM154_Z1_1 Tissue 14 96178685 C T TCL1Ap.V57I 0 76 0.276316 76 WCM154_Z1_1 Tissue 16 10274172 C T GRIN2A p.A33T0 67 0.486842 76 WCM154_Z1_1 Tissue 19 9047229 C A MUC16 p.G11468W 0 760.180723 83 WCM154_Z1_1 Tissue 21 31709709 C A KRTAP27-1 p.R93M 0 600.27907 43 WCM154_Z1_1 Tissue 2 204320216 G A RAPH1 p.R416C 0 104 0.07580 WCM154_Z1_1 Tissue 2 86707345 C T KDM3A p.S791L 0 94 0.85 80WCM154_Z1_1 Tissue 3 107491938 G A BBX p.S457N 0 60 0.19 100 WCM154_Z1_1Tissue 3 153994032 G T DHX36 p.D985E 0 35 0.085714 35 WCM154_Z1_1 Tissue3 19574999 A G KCNH8 p.H911R 0 39 0.314286 35 WCM154_Z1_1 Tissue 348698327 G T CELSR3 p.H581N 0 57 0.571429 42 WCM154_Z1_1 Tissue 4103553339 A G MANBA p.F839L 0 239 0.302521 119 WCM154_Z1_1 Tissue 43318546 G A RGS12 p.D217N 0 151 0.409524 105 WCM154_Z1_1 Tissue 5176882751 T G PRR7 p.C152G 0 129 0.190283 247 WCM154_Z1_1 Tissue 533947380 G A SLC45A2 p.P419L 0 193 0.254902 357 WCM154_Z1_1 Tissue 6138200015 G T TNFAIP3 p.C478F 0 79 0.448276 87 WCM154_Z1_1 Tissue 650683084 C G TFAP2D p.Q99E 0 95 0.295238 105 WCM154_Z1_1 Tissue 7140373613 G C ADCK2 p.E161D 0 125 0.129032 93 WCM154_Z1_1 Tissue 10127520099 G T BCCIP p.K174N 0 42 0.255556 90 WCM155 Plasma 10 49667892 CT ARHGAP22 p.R165Q 0 44 0.807229 83 WCM155 Plasma 1 110033675 C TATXN7L2 p.S497F 0 40 0.260274 73 WCM155 Plasma 11 120337925 G A ARHGEF12p.C921Y 0 53 0.221154 104 WCM155 Plasma 11 20078159 G A NAV2 p.A1662T 035 0.148649 74 WCM155 Plasma 12 131466566 C T GPR133 p.R150W 0 320.810345 58 WCM155 Plasma 12 41966358 G A PDZRN4 p.D593N 0 33 0.394231104 WCM155 Plasma 14 63860559 G C PPP2R5E p.S276R 0 34 0.195652 92WCM155 Plasma 16 76523715 G A CNTNAP4 p.R675H 0 41 0.78481 79 WCM155Plasma 19 41072213 A G SPTBN4 p.K2095R 0 55 0.055556 126 WCM155 Plasma19 41072216 C G SPTBN4 p.A2096G 0 59 0.054688 128 WCM155 Plasma 1951020884 C T LRRC4B p.E696K 0 42 0.318182 66 WCM155 Plasma 2 160082208 CT TANC1 p.A1274V 0 55 0.377778 90 WCM155 Plasma 2 179535859 G T TTNp.P11382T 0 73 0.295082 122 WCM155 Plasma 2 202025453 G C CFLAR p.E364D0 40 0.283951 81 WCM155 Plasma 3 100275801 G A TMEM45A p.A130T 0 370.291262 103 WCM155 Plasma 3 14183242 C T TMEM43 p.L384F 0 47 0.169492118 WCM155 Plasma 5 149263008 G A PDE6A p.R707W 0 43 0.325 120 WCM155Plasma 5 66406010 C T MAST4 p.R481W 0 58 0.211268 142 WCM155 Plasma 7150439339 T G GIMAP5 p.C38G 0 33 0.147368 95 WCM155 Plasma 10 127520099G T BCCIP p.K174N 0 149 0.366013 153 WCM155_Z1_1 Tissue 10 49667892 C TARHGAP22 p.R165Q 0 211 1 129 WCM155_Z1_1 Tissue 1 110033675 C T ATXN7L2p.S497F 0 150 0.066667 180 WCM155_Z1_1 Tissue 1 115282345 T C CSDE1p.Y56C 0 98 0.273438 128 WCM155_Z1_1 Tissue 11 20078159 G A NAV2p.A1662T 0 107 0.388889 108 WCM155_Z1_1 Tissue 12 131466566 C T GPR133p.R150W 0 51 0.979592 49 WCM155_Z1_1 Tissue 1 216737678 T C ESRRGp.I249V 0 169 0.280193 207 WCM155_Z1_1 Tissue 12 41966358 G A PDZRN4p.D593N 0 223 0.508816 397 WCM155_Z1_1 Tissue 1 40703445 A G RLFp.D1024G 0 136 0.201754 228 WCM155_Z1_1 Tissue 14 38218349 G A TTC6p.V857I 0 123 0.680556 216 WCM155_Z1_1 Tissue 15 42146271 G T SPTBN5p.Q3251K 0 173 0.075 80 WCM155_Z1_1 Tissue 17 10532978 G A MYH3 p.A1911V0 60 0.594937 79 WCM155_Z1_1 Tissue 19 2245540 G A SF3A2 p.R114H 0 1220.068966 116 WCM155_Z1_1 Tissue 19 51020884 C T LRRC4B p.E696K 0 1380.439024 123 WCM155_Z1_1 Tissue 19 9088753 A T MUC16 p.I1021N 0 1920.62439 205 WCM155_Z1_1 Tissue 20 31291834 C A COMMD7 p.V173L 0 750.370787 89 WCM155_Z1_1 Tissue 20 47265971 C G PREX1 p.G1058R 0 500.183673 49 WCM155_Z1_1 Tissue 2 141707904 T A LRP1B p.R1012S 0 1550.333333 87 WCM155_Z1_1 Tissue 2 241680699 C A KIF1A p.E1145* 0 1540.52381 84 WCM155_Z1_1 Tissue 3 148880630 C T HPS3 p.P816S 0 52 0.5 40WCM155_Z1_1 Tissue 3 9953155 G T IL17RE p.M367I 0 68 0.061224 49WCM155_Z1_1 Tissue 5 149263008 G A PDE6A p.R707W 0 153 0.341615 161WCM155_Z1_1 Tissue 5 66406010 C T MAST4 p.R481W 0 80 0.313953 86WCM155_Z1_1 Tissue 7 150439339 T G GIMAP5 p.C38G 0 231 0.195946 296WCM155_Z1_1 Tissue 7 31378317 A G NEUROD6 p.L189P 0 88 0.315068 73WCM155_Z1_1 Tissue 7 6465708 C A DAGLB p.G323C 0 65 0.095238 63WCM155_Z1_1 Tissue 8 146002914 C T ZNF34 p.R91Q 0 101 0.547826 115WCM155_Z1_1 Tissue X 110492205 C A CAPN6 p.M413I 0 55 0.4375 48WCM155_Z1_1 Tissue 10 127520099 G T BCCIP p.K174N 0 149 0.227758 281WCM155_Z2_1 Tissue 10 49667892 C T ARHGAP22 p.R165Q 0 211 0.771739 184WCM155_Z2_1 Tissue 11 100558491 G T ARHGAP42 p.E28* 0 44 0.083333 36WCM155_Z2_1 Tissue 11 111590677 G A SIK2 p.R482Q 0 49 0.096774 62WCM155_Z2_1 Tissue 1 115282345 T C CSDE1 p.Y56C 0 98 0.236641 131WCM155_Z2_1 Tissue 11 20078159 G A NAV2 p.A1662T 0 107 0.134146 82WCM155_Z2_1 Tissue 11 56345191 A G OR5M10 p.S3P 0 53 0.369565 46WCM155_Z2_1 Tissue 1 216737678 T C ESRRG p.I249V 0 169 0.390244 246WCM155_Z2_1 Tissue 12 41966358 G A PDZRN4 p.D593N 0 223 0.443662 568WCM155_Z2_1 Tissue 12 6701583 C T CHD4 p.R975H 0 31 0.080645 62WCM155_Z2_1 Tissue 1 40703445 A G RLF p.D1024G 0 136 0.250784 319WCM155_Z2_1 Tissue 14 38218349 G A TTC6 p.V857I 0 123 0.47541 61WCM155_Z2_1 Tissue 16 1476220 T C C16orf91 p.R135G 0 59 0.070175 57WCM155_Z2_1 Tissue 16 27788943 G A KIAA0556 p.D1522N 0 91 0.081633 49WCM155_Z2_1 Tissue 16 31504801 G A C16orf58 p.R335C 0 74 0.052632 152WCM155_Z2_1 Tissue 17 10532978 G A MYH3 p.A1911V 0 60 0.444444 126WCM155_Z2_1 Tissue 17 41166132 C T IFI35 p.S226L 0 41 0.363636 44WCM155_Z2_1 Tissue 18 2599039 T C NDC80 p.Y415H 0 66 0.555556 72WCM155_Z2_1 Tissue 19 51020884 C T LRRC4B p.E696K 0 138 0.242236 161WCM155_Z2_1 Tissue 19 9088753 A T MUC16 p.I1021N 0 192 0.513089 191WCM155_Z2_1 Tissue 19 9089011 G C MUC16 p.A935G 0 94 0.52381 63WCM155_Z2_1 Tissue 20 31291834 C A COMMD7 p.V173L 0 75 0.245614 57WCM155_Z2_1 Tissue 2 141707904 T A LRP1B p.R1012S 0 155 0.22335 197WCM155_Z2_1 Tissue 2 160082208 C T TANC1 p.A1274V 0 167 0.553957 139WCM155_Z2_1 Tissue 2 166740465 G A TTC21B p.R1175* 0 47 0.103448 58WCM155_Z2_1 Tissue 22 40055853 C T CACNA1I p.A867V 0 141 0.105263 76WCM155_Z2_1 Tissue 2 241680699 C A KIF1A p.E1145* 0 154 0.26087 92WCM155_Z2_1 Tissue 3 100275801 G A TMEM45A p.A130T 0 69 0.242857 70WCM155_Z2_1 Tissue 3 179371120 G T USP13 p.R36L 0 33 0.067416 89WCM155_Z2_1 Tissue 4 71554576 C A UTP3 p.A61D 0 45 0.086207 58WCM155_Z2_1 Tissue 5 149263008 G A PDE6A p.R707W 0 153 0.289017 173WCM155_Z2_1 Tissue 5 161115966 G A GABRA6 p.M79I 0 169 0.248705 193WCM155_Z2_1 Tissue 5 66406010 C T MAST4 p.R481W 0 80 0.166667 72WCM155_Z2_1 Tissue 7 150439339 T G GIMAP5 p.C38G 0 231 0.284672 411WCM155_Z2_1 Tissue 7 31378317 A G NEUROD6 p.L189P 0 88 0.16129 93WCM155_Z2_1 Tissue 8 146002914 C T ZNF34 p.R91Q 0 101 0.314685 143WCM155_Z2_1 Tissue X 110492205 C A CAPN6 p.M413I 0 55 0.28169 71WCM155_Z2_1 Tissue 11 65984211 C T PACS1 p.R315W 0 31 0.136364 66 WCM156Plasma 11 7960298 A C OR10A3 p.M257R 0 32 0.084507 71 WCM156 Plasma 2224898163 T A UPB1 p.C116S 0 33 0.108696 46 WCM156 Plasma 2 64682532 G ALGALSL p.V31M 0 34 0.071429 42 WCM156 Plasma 6 32183057 G A NOTCH4p.P656L 0 31 0.06 50 WCM156 Plasma 6 74063875 A T DPPA5 p.V25E 0 310.056338 71 WCM156 Plasma 10 47000144 C A GPRIN2 p.P422T 0 204 0.144186215 WCM156_Z5_1 Tissue 10 61835487 C T ANK3 p.G1718R 0 108 0.320513 78WCM156_Z5_1 Tissue 11 17741636 C T MYOD1 p.R103C 0 57 0.2 40 WCM156_Z5_1Tissue 1 1268053 T G TAS1R3 p.V381G 0 63 0.364865 74 WCM156_Z5_1 Tissue11 46916329 G A LRP4 p.R451W 0 94 0.159574 94 WCM156_Z5_1 Tissue 1176255526 A T C11orf30 p.Q978L 0 67 0.268293 41 WCM156_Z5_1 Tissue 117960298 A C OR10A3 p.M257R 0 95 0.1875 112 WCM156_Z5_1 Tissue 1235972382 T C LYST p.N579S 0 147 0.19209 177 WCM156_Z5_1 Tissue 1257858962 C A GLI1 p.P153H 0 154 0.051813 193 WCM156_Z5_1 Tissue 1295927279 C T USP44 p.E252K 0 34 0.255814 43 WCM156_Z5_1 Tissue 1346718638 G A LCP1 p.R398W 0 90 0.092308 65 WCM156_Z5_1 Tissue 1589386693 G C ACAN p.A289P 0 40 0.226415 53 WCM156_Z5_1 Tissue 1631388172 G T ITGAX p.G854V 0 178 0.20904 177 WCM156_Z5_1 Tissue 1658314519 G C PRSS54 p.S266C 0 188 0.143713 167 WCM156_Z5_1 Tissue 1726902206 T G ALDOC p.K87Q 0 204 0.263959 197 WCM156_Z5_1 Tissue 1751063816 G T C17orf112 p.E20D 0 134 0.120482 166 WCM156_Z5_1 Tissue 177247261 G C ACAP1 p.E219Q 0 184 0.291667 144 WCM156_Z5_1 Tissue 177577505 T G TP53 p.D259A 0 127 0.346457 127 WCM156_Z5_1 Tissue 1 7880612C G PER3 p.I615M 0 65 0.418182 55 WCM156_Z5_1 Tissue 18 50994287 A T DCCp.S1215C 0 197 0.308824 204 WCM156_Z5_1 Tissue 19 36581409 G A WDR62p.G674E 0 112 0.11 100 WCM156_Z5_1 Tissue 19 37368472 G A ZNF345 p.R247Q0 72 0.188679 53 WCM156_Z5_1 Tissue 19 41008803 A T SPTBN4 p.E442V 0 1270.256198 121 WCM156_Z5_1 Tissue 19 46974024 C A PNMAL1 p.G90V 0 2000.297468 158 WCM156_Z5_1 Tissue 19 51560004 T G KLK13 p.N225T 0 1710.195652 138 WCM156_Z5_1 Tissue 19 56090128 G T ZNF579 p.S293Y 0 540.115385 52 WCM156_Z5_1 Tissue 19 57985004 T C ZNF772 p.S370G 0 1280.287879 198 WCM156_Z5_1 Tissue 20 3673226 G T SIGLEC1 p.C1324* 0 1300.26087 92 WCM156_Z5_1 Tissue 21 30699104 T A BACH1 p.L320H 0 910.290323 93 WCM156_Z5_1 Tissue 2 191862655 C G STAT1 p.E238Q 0 68 0.3 80WCM156_Z5_1 Tissue 22 24898163 T A UPB1 p.C116S 0 110 0.234043 94WCM156_Z5_1 Tissue 22 30769717 G T CCDC157 p.E489D 0 106 0.073394 109WCM156_Z5_1 Tissue 2 232137734 A G ARMC9 p.D426G 0 239 0.169811 265WCM156_Z5_1 Tissue 22 41077031 G T MCHR1 p.G123V 0 107 0.283951 81WCM156_Z5_1 Tissue 2 27447269 G A CAD p.G389R 0 161 0.291005 189WCM156_Z5_1 Tissue 3 11059028 G A SLC6A1 p.R44Q 0 121 0.256944 144WCM156_Z5_1 Tissue 3 170716017 T A SLC2A2 p.N447Y 0 37 0.217391 46WCM156_Z5_1 Tissue 3 180337072 A G CCDC39 p.I747T 0 67 0.27027 37WCM156_Z5_1 Tissue 3 196541356 G A PAK2 p.E324K 0 104 0.289474 76WCM156_Z5_1 Tissue 3 4718403 A C ITPR1 p.E947A 0 129 0.119658 117WCM156_Z5_1 Tissue 3 69134338 A C ARL6IP5 p.Y47S 0 48 0.410256 39WCM156_Z5_1 Tissue 4 123164219 T G KIAA1109 p.S1580A 0 119 0.163265 98WCM156_Z5_1 Tissue 4 55593428 T A KIT p.F529I 0 81 0.264368 87WCM156_Z5_1 Tissue 4 8229765 C G SH3TC1 p.Q782E 0 51 0.169014 71WCM156_Z5_1 Tissue 7 103205909 A G RELN p.F1676L 0 69 0.223684 76WCM156_Z5_1 Tissue 7 150439456 A C GIMAP5 p.K77Q 0 87 0.158273 139WCM156_Z5_1 Tissue 7 36450221 A T ANLN p.I399F 0 130 0.261261 111WCM156_Z5_1 Tissue 8 121209117 G T COL14A1 p.R175I 0 105 0.152778 144WCM156_Z5_1 Tissue 8 88218228 C G CNBD1 p.H147D 0 139 0.216 125WCM156_Z5_1 Tissue 8 94146540 G A C8orf87 p.Q97* 0 84 0.169231 130WCM156_Z5_1 Tissue 9 139730224 A C RABL6 p.N246H 0 141 0.194286 175WCM156_Z5_1 Tissue 9 71395309 C A FAM122A p.P77T 0 43 0.078947 38WCM156_Z5_1 Tissue 9 71628527 A T PRKACG p.L161H 0 79 0.148936 94WCM156_Z5_1 Tissue 9 90343258 C T CTSL p.P115S 0 64 0.296296 54WCM156_Z5_1 Tissue X 40514221 G C MED14 p.P1355R 0 51 0.227273 44WCM156_Z5_1 Tissue 12 132325175 G T MMP17 p.M160I 0 32 0.050633 79WCM158 Plasma 15 43749223 C G TP53BP1 p.S523T 0 58 0.060241 83 WCM158Plasma 15 43749224 T C TP53BP1 p.S523G 0 59 0.059524 84 WCM158 Plasma 1740706506 C T HSD17B1 p.T208M 0 42 0.071429 56 WCM158 Plasma 17 4098298 GT ANKFY1 p.H449Q 0 31 0.054795 73 WCM158 Plasma 2 234581202 C T UGT1A9p.R208W 0 40 0.078431 51 WCM158 Plasma 9 130540902 G T SH2D3C p.T2K 0 360.060606 66 WCM158 Plasma X 37027959 C G FAM47C p.D492E 0 39 0.054795 73WCM158 Plasma 1 103404628 G A COL11A1 p.P1134L 0 76 0.169811 53WCM158_X1_1 Tissue 11 1993910 T G MRPL23 p.V140G 0 163 0.238095 189WCM158_X1_1 Tissue 1 153516257 T C S100A4 p.D95G 0 200 0.205882 238WCM158_X1_1 Tissue 11 6789770 A G OR2AG2 p.V140A 0 126 0.196429 112WCM158_X1_1 Tissue 1 181701707 C T CACNA1E p.R829* 0 82 0.086207 116WCM158_X1_1 Tissue 1 182500016 A G RGSL1 p.I779V 0 93 0.284615 130WCM158_X1_1 Tissue 1 186934669 C T PLA2G4A p.L570F 0 118 0.141593 113WCM158_X1_1 Tissue 11 94349694 C A PIWIL4 p.T660N 0 42 0.08 50WCM158_X1_1 Tissue 1 217783692 T A GPATCH2 p.K357* 0 72 0.346154 78WCM158_X1_1 Tissue 13 101266669 G T TMTC4 p.R599S 0 66 0.071429 42WCM158_X1_1 Tissue 1 45271330 C T PLK3 p.R641W 0 91 0.325843 89WCM158_X1_1 Tissue 14 65246451 C G SPTB p.D1489H 0 46 0.392157 51WCM158_X1_1 Tissue 15 63008544 C A TLN2 p.N883K 0 46 0.096774 31WCM158_X1_1 Tissue 16 602629 C T CAPN15 p.P921L 0 40 0.25 32 WCM158_X1_1Tissue 16 61687934 C T CDH8 p.V660I 0 92 0.32 50 WCM158_X1_1 Tissue 1739182914 C T KRTAP1-5 p.R165H 0 179 0.202899 207 WCM158_X1_1 Tissue 1747696426 A C SPOP p.F133V 0 130 0.226415 106 WCM158_X1_1 Tissue 1748941097 G C TOB1 p.I94M 0 36 0.242424 33 WCM158_X1_1 Tissue 17 73488775C T KIAA0195 p.S606F 0 186 0.221519 158 WCM158_X1_1 Tissue 17 8408097 TG MYH10 p.K1141Q 0 167 0.416 125 WCM158_X1_1 Tissue 19 20117462 T GZNF682 p.K283N 0 69 0.160714 56 WCM158_X1_1 Tissue 19 2767654 C A SGTAp.G44V 0 64 0.241379 58 WCM158_X1_1 Tissue 20 4771204 G A RASSF2 p.R144C0 41 0.159091 44 WCM158_X1_1 Tissue 2 110373058 C T SOWAHC p.P331L 0 1100.06383 94 WCM158_X1_1 Tissue 3 101086714 G A SENP7 p.S313F 0 70 0.5243982 WCM158_X1_1 Tissue 3 131101026 G A NUDT16 p.R92H 0 95 0.244898 98WCM158_X1_1 Tissue 3 64589750 C G ADAMTS9 p.G1199R 0 57 0.081967 61WCM158_X1_1 Tissue 5 140552589 A G PCDHB7 p.E58G 0 128 0.290323 93WCM158_X1_1 Tissue 5 176894484 C T DBN1 p.V159M 0 103 0.21978 91WCM158_X1_1 Tissue 6 43306314 C A ZNF318 p.D1808Y 0 133 0.103774 106WCM158_X1_1 Tissue 7 5427854 C A TNRC18 p.R534L 0 60 0.1 60 WCM158_X1_1Tissue 8 36661568 C A KCNU1 p.S113R 0 40 0.078947 38 WCM158_X1_1 Tissue9 116151886 C T ALAD p.R236Q 0 62 0.304348 92 WCM158_X1_1 Tissue X127186074 C T ACTRT1 p.V38I 0 47 0.225806 31 WCM158_X1_1 Tissue X1409310 G T CSF2RA p.G185V 0 47 0.065217 46 WCM158_X1_1 Tissue 1109649197 G T C1orf194 p.N133K 0 34 0.157895 38 WCM15_Z1_1 Tissue 1159811056 A T PLAC1L p.N60I 0 62 0.145161 62 WCM15_Z1_1 Tissue 1166039635 C T FAM78B p.R210Q 0 216 0.450199 251 WCM15_Z1_1 Tissue 1181702034 C T CACNA1E p.R938W 0 173 0.42 200 WCM15_Z1_1 Tissue 12121947572 T A KDM2B p.K482M 0 131 0.122093 172 WCM15_Z1_1 Tissue 1222005053 C T ABCC9 p.R916Q 0 62 0.493151 73 WCM15_Z1_1 Tissue 1 22332229C T CELA3A p.P101L 0 145 0.138158 152 WCM15_Z1_1 Tissue 1 233275531 G TPCNXL2 p.Y1196* 0 104 0.481132 106 WCM15_Z1_1 Tissue 1 245019208 C THNRNPU p.G722E 0 41 0.491525 59 WCM15_Z1_1 Tissue 12 57437688 C A MYO1Ap.E282* 0 342 0.488722 399 WCM15_Z1_1 Tissue 13 61986159 C A PCDH20p.K691N 0 321 0.058511 188 WCM15_Z1_1 Tissue 15 62232878 T A VPS13Cp.M1857L 0 117 0.150943 106 WCM15_Z1_1 Tissue 17 3661050 T C ITGAEp.T324A 0 91 0.127273 110 WCM15_Z1_1 Tissue 17 7576865 A C TP53 p.Y327*0 131 0.965 200 WCM15_Z1_1 Tissue 19 1119989 C T SBNO2 p.A395T 0 144 0.5112 WCM15_Z1_1 Tissue 19 2272982 C T OAZ1 p.R188* 0 200 0.412698 189WCM15_Z1_1 Tissue 19 31039968 C A ZNF536 p.L1148M 0 193 0.082781 302WCM15_Z1_1 Tissue 19 36268761 C T ARHGAP33 p.A47V 0 160 0.297619 336WCM15_Z1_1 Tissue 19 51021577 C T LRRC4B p.G465S 0 140 0.628141 199WCM15_Z1_1 Tissue 20 25456818 C T NINL p.E1037K 0 231 0.926554 177WCM15_Z1_1 Tissue 20 30072003 G A REM1 p.E223K 0 62 0.111111 72WCM15_Z1_1 Tissue 20 33565758 T A MYH7B p.L26M 0 37 0.12766 47WCM15_Z1_1 Tissue 2 17998038 G A MSGN1 p.G85S 0 66 0.541667 72WCM15_Z1_1 Tissue 2 45601 C T FAM110C p.R262Q 0 87 0.631579 95WCM15_Z1_1 Tissue 2 55439884 G C CLHC1 p.Q142E 0 109 0.125 64 WCM15_Z1_1Tissue 3 100949982 C A IMPG2 p.V1081L 0 96 0.183333 120 WCM15_Z1_1Tissue 5 150885539 G T FAT2 p.P4213T 0 105 0.661692 201 WCM15_Z1_1Tissue 5 179200970 G T MAML1 p.A715S 0 109 0.118012 161 WCM15_Z1_1Tissue 5 79031784 A C CMYA5 p.N2399T 0 109 0.376344 93 WCM15_Z1_1 Tissue6 116837044 C A FAM26E p.S274R 0 151 0.104294 163 WCM15_Z1_1 Tissue 632781509 C A HLA-DOB p.A249S 0 36 0.106383 47 WCM15_Z1_1 Tissue 643271913 C A SLC22A7 p.T508N 0 109 0.077465 142 WCM15_Z1_1 Tissue 723213848 T A KLHL7 p.F564L 0 125 0.463087 149 WCM15_Z1_1 Tissue 8131848611 G T ADCY8 p.L863M 0 67 0.471698 53 WCM15_Z1_1 Tissue 817065500 A G ZDHHC2 p.H210R 0 127 0.957747 71 WCM15_Z1_1 Tissue 895161094 A G CDH17 p.L602P 0 81 0.104651 86 WCM15_Z1_1 Tissue 9 17366668A T CNTLN p.K647M 0 114 0.051948 77 WCM15_Z1_1 Tissue 9 75406899 G ATMC1 p.W441* 0 216 0.880597 67 WCM15_Z1_1 Tissue X 12725014 G C FRMPD4p.V423L 0 32 0.104348 115 WCM15_Z1_1 Tissue 11 103908356 G C DDI1p.S269T 0 47 0.209677 62 WCM160 Plasma 11 10820640 C A EIF4G2 p.V853L 031 0.068182 44 WCM160 Plasma 12 123187305 A T HCAR2 p.L176M 0 360.088889 45 WCM160 Plasma 1 23337579 G A C1orf234 p.R61W 0 37 0.21739169 WCM160 Plasma 12 9241818 G T A2M p.F916L 0 64 0.058824 119 WCM160Plasma 14 20344468 G T OR4K2 p.L14F 0 81 0.056604 106 WCM160 Plasma 1420871890 G A TEP1 p.R396C 0 51 0.0625 64 WCM160 Plasma 16 10524584 A GATF7IP2 p.E36G 0 63 0.290323 93 WCM160 Plasma 16 22132374 C A VWA3Ap.P401Q 0 35 0.064516 93 WCM160 Plasma 19 51132652 G A SYT3 p.R394W 0 330.12963 54 WCM160 Plasma 2 145157153 T C ZEB2 p.N534S 0 42 0.098592 71WCM160 Plasma 2 61233705 A C PUS10 p.L152R 0 55 0.135417 96 WCM160Plasma 4 126373323 G A FAT4 p.G3718S 0 76 0.064516 93 WCM160 Plasma 446973232 C G GABRA4 p.V248L 0 62 0.075269 93 WCM160 Plasma 5 140626723 CT PCDHB15 p.A526V 0 62 0.056338 71 WCM160 Plasma 7 47332452 G C TNS3p.P1275R 0 41 0.076923 65 WCM160 Plasma 7 63726554 G T ZNF679 p.K181N 075 0.072917 96 WCM160 Plasma 7 77797283 G T MAGI2 p.A849D 0 58 0.06741689 WCM160 Plasma 9 135801105 C T TSC1 p.E78K 0 33 0.103896 77 WCM160Plasma X 142718057 G A SLITRK4 p.H290Y 0 45 0.117647 68 WCM160 Plasma X32867862 G C DMD p.L57V 0 62 0.150538 93 WCM160 Plasma 4 37448316 G TKIAA1239 p.R1569L 0 73 0.067797 59 WCM160_X1_1 Tissue 6 56857309 G ABEND6 p.R85Q 0 65 0.065934 91 WCM160_X1_1 Tissue 11 103908356 G C DDI1p.S269T 0 61 0.209677 62 WCM160_Z7_1 Tissue 11 55944544 G T OR5J2p.G151C 0 309 0.109467 338 WCM160_Z7_1 Tissue 1 179077074 C G ABL2p.V1110L 0 268 0.098684 304 WCM160_Z7_1 Tissue 1 201751699 G A NAV1p.G687R 0 92 0.269231 156 WCM160_Z7_1 Tissue 12 122966631 G A ZCCHC8p.R246W 0 116 0.067416 89 WCM160_Z7_1 Tissue 12 123187305 A T HCAR2p.L176M 0 159 0.107843 102 WCM160_Z7_1 Tissue 12 50642451 C A LIMA1p.K28N 0 94 0.109589 73 WCM160_Z7_1 Tissue 12 97137219 T C C12orf55p.V2420A 0 173 0.0875 240 WCM160_Z7_1 Tissue 13 79942892 G T RBM26p.P290T 0 82 0.082192 73 WCM160_Z7_1 Tissue 16 10524584 A G ATF7IP2p.E36G 0 32 0.392157 51 WCM160_Z7_1 Tissue 16 89346220 C T ANKRD11p.V2244I 0 71 0.0625 96 WCM160_Z7_1 Tissue 19 36515422 G A CLIP3 p.A265V0 92 0.096491 114 WCM160_Z7_1 Tissue 19 51132652 G A SYT3 p.R394W 0 1000.154639 97 WCM160_Z7_1 Tissue 19 56702288 C A ZSCAN5B p.Q219H 0 58 0.1250 WCM160_Z7_1 Tissue 19 9061843 C A MUC16 p.E8535* 0 92 0.206186 97WCM160_Z7_1 Tissue 2 239072961 C T FAM132B p.R283C 0 47 0.168421 95WCM160_Z7_1 Tissue 2 61233705 A C PUS10 p.L152R 0 60 0.196078 51WCM160_Z7_1 Tissue 3 179399759 G A USP13 p.V88I 0 114 0.085938 128WCM160_Z7_1 Tissue 3 64666930 C T ADAMTS9 p.R209H 0 163 0.090395 177WCM160_Z7_1 Tissue 4 185697802 C A ACSL1 p.V198F 0 63 0.405797 69WCM160_Z7_1 Tissue 4 46973232 C G GABRA4 p.V248L 0 92 0.129771 131WCM160_Z7_1 Tissue 7 47332452 G C TNS3 p.P1275R 0 128 0.056497 177WCM160_Z7_1 Tissue 7 88965559 C G ZNF804B p.S1088* 0 46 0.150685 73WCM160_Z7_1 Tissue 8 42024806 G C AP3M2 p.V310L 0 49 0.082949 217WCM160_Z7_1 Tissue X 142121979 A G SPANXN4 p.K83E 0 55 0.135593 59WCM160_Z7_1 Tissue X 142718057 G A SLITRK4 p.H290Y 0 48 0.183673 49WCM160_Z7_1 Tissue 10 55582535 C T PCDH15 p.E1651K 0 71 0.09 100 WCM161Plasma 12 121435460 G T HNF1A p.S498I 0 36 0.066667 60 WCM161 Plasma 1285279766 C A SLC6A15 p.R124I 0 50 0.058824 85 WCM161 Plasma 1 32502610 CT KHDRBS1 p.R291W 0 54 0.121951 82 WCM161 Plasma 13 46701794 C T LCP1p.E606K 0 62 0.561224 98 WCM161 Plasma 13 46701796 A C LCP1 p.V605G 0 620.565657 99 WCM161 Plasma 1 38288331 G C MTF1 p.S410C 0 33 0.063492 63WCM161 Plasma 14 31581741 C A HECTD1 p.L2053F 0 37 0.097222 72 WCM161Plasma 15 55912280 C T PRTG p.R1128Q 0 72 0.130435 115 WCM161 Plasma 1563419792 G A LACTB p.D286N 0 46 0.069444 72 WCM161 Plasma 15 90169242 CT TICRR p.P1851L 0 45 0.058252 103 WCM161 Plasma 17 10316027 T C MYH8p.Y389C 0 53 0.118421 76 WCM161 Plasma 17 58040371 C T RNFT1 p.V111I 034 0.109375 64 WCM161 Plasma 17 7578265 A G TP53 p.I195T 0 59 0.40506379 WCM161 Plasma 17 79914822 C T NOTUM p.R275H 0 53 0.075758 66 WCM161Plasma 18 25589803 G A CDH2 p.R194W 0 46 0.090909 88 WCM161 Plasma 185395676 C T EPB41L3 p.V1002M 0 59 0.462963 108 WCM161 Plasma 19 13054391A G CALR p.N334S 0 46 0.2 50 WCM161 Plasma 19 54301601 G T NLRP12p.H941Q 0 52 0.169231 65 WCM161 Plasma 21 46330230 G A ITGB2 p.S39L 0 640.054054 74 WCM161 Plasma 3 128204654 C T GATA2 p.G263R 0 33 0.288462 52WCM161 Plasma 4 100572577 G A RP11- p.R1077C 0 52 0.059406 101 WCM161Plasma 766F14.2 5 37370969 G T NUP155 p.D37E 0 47 0.078947 38 WCM161Plasma 6 56472225 G A DST p.P2190S 0 52 0.2 70 WCM161 Plasma 6 88853727C A CNR1 p.D423Y 0 34 0.147059 68 WCM161 Plasma 7 151810392 G A GALNT11p.R381Q 0 73 0.111111 108 WCM161 Plasma X 151123553 G A GABRE p.R381C 060 0.135593 118 WCM161 Plasma 10 55582535 C T PCDH15 p.E1651K 0 420.405405 37 WCM161_Z1_1 Tissue 1 156811514 C T INSRR p.R1157H 0 690.484211 95 WCM161_Z1_1 Tissue 11 6422647 G A APBB1 p.R506W 0 1530.087432 183 WCM161_Z1_1 Tissue 11 76371084 C T LRRC32 p.R518Q 0 390.151515 66 WCM161_Z1_1 Tissue 12 120572361 C T GCN1L1 p.R2393H 0 1010.271605 81 WCM161_Z1_1 Tissue 13 46701794 C T LCP1 p.E606K 0.007752 2580.821149 766 WCM161_Z1_1 Tissue 13 46701796 A C LCP1 p.V605G 0.007843255 0.821382 767 WCM161_Z1_1 Tissue 13 67801938 C A PCDH9 p.R212I 0 1070.103448 58 WCM161_Z1_1 Tissue 1 38288331 G C MTF1 p.S410C 0 99 0.162580 WCM161_Z1_1 Tissue 14 24686398 T A NEDD8 p.I61F 0 104 0.198758 161WCM161_Z1_1 Tissue 14 45414997 T G KLHL28 p.K45N 0 108 0.111111 108WCM161_Z1_1 Tissue 14 92560158 C G ATXN3 p.L84F 0 69 0.087912 91WCM161_Z1_1 Tissue 15 74489709 T C STRA6 p.D79G 0 106 0.524272 103WCM161_Z1_1 Tissue 15 90169242 C T TICRR p.P1851L 0 95 0.390244 41WCM161_Z1_1 Tissue 16 3706746 G T DNASE1 p.R143L 0 95 0.192053 151WCM161_Z1_1 Tissue 16 57503661 G A POLR2C p.V143M 0 64 0.184466 103WCM161_Z1_1 Tissue 17 7578265 A G TP53 p.I195T 0 199 0.782313 147WCM161_Z1_1 Tissue 17 79914822 C T NOTUM p.R275H 0 150 0.339394 165WCM161_Z1_1 Tissue 18 5395676 C T EPB41L3 p.V1002M 0 198 0.450777 193WCM161_Z1_1 Tissue 19 50804981 C T MYH14 p.R1804W 0 36 0.28125 32WCM161_Z1_1 Tissue 19 51215331 C T SHANK1 p.R278H 0 93 0.26 50WCM161_Z1_1 Tissue 19 54301601 G T NLRP12 p.H941Q 0 143 0.417722 79WCM161_Z1_1 Tissue 2 186669449 T A FSIP2 p.L5139Q 0 65 0.644444 45WCM161_Z1_1 Tissue 2 54858230 C T SPTBN1 p.Q1016* 0 106 0.152542 118WCM161_Z1_1 Tissue 3 128204654 C T GATA2 p.G263R 0 63 0.471698 53WCM161_Z1_1 Tissue 3 49698303 C T BSN p.R3009C 0 135 0.053476 187WCM161_Z1_1 Tissue 3 57827029 C T SLMAP p.T117I 0 56 0.153846 78WCM161_Z1_1 Tissue 3 77147468 G A ROBO2 p.R122Q 0 219 0.144876 283WCM161_Z1_1 Tissue 3 97590787 C A CRYBG3 p.T250N 0 216 0.061584 341WCM161_Z1_1 Tissue 6 39271778 C T KCNK17 p.A215T 0 70 0.25 80WCM161_Z1_1 Tissue 6 88853727 C A CNR1 p.D423Y 0 53 0.263889 72WCM161_Z1_1 Tissue 7 4285392 G C SDK1 p.E2112D 0 81 0.317829 129WCM161_Z1_1 Tissue 7 87046777 C T ABCB4 p.G845S 0 155 0.11828 186WCM161_Z1_1 Tissue 9 140267385 C T EXD3 p.R145H 0 154 0.161137 211WCM161_Z1_1 Tissue 9 35043107 G A C9orf131 p.V161M 0 102 0.401235 162WCM161_Z1_1 Tissue 11 62295576 G A AHNAK p.L2105F 0 38 0.083333 36WCM161_Z15_1 Tissue 1 32502610 C T KHDRBS1 p.R291W 0 129 0.292929 99WCM161_Z15_1 Tissue 13 38211227 G A TRPC4 p.T916M 0 45 0.137931 116WCM161_Z15_1 Tissue 13 46701796 A C LCP1 p.V605G 0.007843 255 0.465347202 WCM161_Z15_1 Tissue 15 63419792 G A LACTB p.D286N 0 99 0.330435 115WCM161_Z15_1 Tissue 1 77528726 G A ST6GALNAC5 p.M282I 0 53 0.329114 79WCM161_Z15_1 Tissue 17 7578265 A G TP53 p.I195T 0 199 0.991525 118WCM161_Z15_1 Tissue 18 25589803 G A CDH2 p.R194W 0 246 0.276923 195WCM161_Z15_1 Tissue 19 54301601 G T NLRP12 p.H941Q 0 143 0.596154 52WCM161_Z15_1 Tissue 20 57428418 C A GNAS p.A33D 0 67 0.204545 44WCM161_Z15_1 Tissue 2 186669449 T A FSIP2 p.L5139Q 0 65 0.262295 61WCM161_Z15_1 Tissue 2 32474933 C T NLRC4 p.R667Q 0 64 0.258824 85WCM161_Z15_1 Tissue 2 54858230 C T SPTBN1 p.Q1016* 0 106 0.829787 47WCM161_Z15_1 Tissue 3 128204654 C T GATA2 p.G263R 0 63 0.540541 37WCM161_Z15_1 Tissue 4 100572577 G A RP11- p.R1077C 0 63 0.21831 142WCM161_Z15_1 Tissue 766F14.2 6 88853727 C A CNR1 p.D423Y 0 53 0.375 48WCM161_Z15_1 Tissue 8 118849393 G A EXT1 p.P337L 0 155 0.119048 168WCM161_Z15_1 Tissue 9 35043107 G A C9orf131 p.V161M 0 102 0.497041 169WCM161_Z15_1 Tissue 10 55582535 C T PCDH15 p.E1651K 0 42 0.26 50WCM161_Z6_1 Tissue 11 76371084 C T LRRC32 p.R518Q 0 39 0.136364 66WCM161_Z6_1 Tissue 1 201179977 G A IGFN1 p.G1986S 0 34 0.125 56WCM161_Z6_1 Tissue 12 120572361 C T GCN1L1 p.R2393H 0 101 0.15625 96WCM161_Z6_1 Tissue 13 46701794 C T LCP1 p.E606K 0.007752 258 0.769366568 WCM161_Z6_1 Tissue 13 46701796 A C LCP1 p.V605G 0.007843 2550.768014 569 WCM161_Z6_1 Tissue 1 38288331 G C MTF1 p.S410C 0 990.072727 110 WCM161_Z6_1 Tissue 14 24686398 T A NEDD8 p.I61F 0 1040.067308 104 WCM161_Z6_1 Tissue 14 24801858 G A ADCY4 p.A130V 0 390.102564 39 WCM161_Z6_1 Tissue 15 74489709 T C STRA6 p.D79G 0 1060.297297 111 WCM161_Z6_1 Tissue 15 90169242 C T TICRR p.P1851L 0 950.141026 78 WCM161_Z6_1 Tissue 16 57503661 G A POLR2C p.V143M 0 640.108434 83 WCM161_Z6_1 Tissue 17 7578265 A G TP53 p.I195T 0 1990.557692 208 WCM161_Z6_1 Tissue 17 79914822 C T NOTUM p.R275H 0 1500.07971 138 WCM161_Z6_1 Tissue 2 186669449 T A FSIP2 p.L5139Q 0 650.322034 59 WCM161_Z6_1 Tissue 2 54858230 C T SPTBN1 p.Q1016* 0 1060.142857 91 WCM161_Z6_1 Tissue 3 123385148 C T MYLK p.R1250H 0 380.078431 51 WCM161_Z6_1 Tissue 3 128204654 C T GATA2 p.G263R 0 630.401709 117 WCM161_Z6_1 Tissue 3 51431267 G T RBM15B p.E813* 0 620.337349 83 WCM161_Z6_1 Tissue 5 23509657 C T PRDM9 p.R50C 0 34 0.075 40WCM161_Z6_1 Tissue 6 39271778 C T KCNK17 p.A215T 0 70 0.240506 79WCM161_Z6_1 Tissue 7 151810392 G A GALNT11 p.R381Q 0 81 0.084746 59WCM161_Z6_1 Tissue 7 4285392 G C SDK1 p.E2112D 0 81 0.07362 163WCM161_Z6_1 Tissue 8 77766195 A C ZFHX4 p.E2346D 0 46 0.142857 98WCM161_Z6_1 Tissue 9 140267385 C T EXD3 p.R145H 0 154 0.148936 235WCM161_Z6_1 Tissue 9 35043107 G A C9orf131 p.V161M 0 102 0.310345 145WCM161_Z6_1 Tissue X 79281236 G A TBX22 p.R198H 0 57 0.090909 66WCM161_Z6_1 Tissue 1 16890515 C A NBPF1 p.V1115L 0 104 0.055901 161WCM162 Plasma 1 169679606 T C SELL p.K32R 0 38 0.637255 102 WCM162Plasma 12 13232864 A G KIAA1467 p.Q595R 0 40 0.223214 112 WCM162 Plasma12 57871258 C T ARHGAP9 p.R247H 0 31 0.255319 94 WCM162 Plasma 1453112919 G C ERO1L p.F433L 0 51 0.063636 110 WCM162 Plasma 14 73464896 CA ZFYVE1 p.G204V 0 39 0.265487 113 WCM162 Plasma 16 51175796 G A SALL1p.L113F 0 52 0.323529 136 WCM162 Plasma 17 42463069 G T ITGA2B p.Q142K 040 0.505376 93 WCM162 Plasma 18 12122424 G A ANKRD62 p.V455I 0 400.239437 71 WCM162 Plasma 2 177016375 C T HOXD4 p.S5L 0 46 0.051471 136WCM162 Plasma 2 234106805 C A INPP5D p.P908T 0 33 0.068627 102 WCM162Plasma 2 88828747 C T TEX37 p.R100C 0 40 0.054054 111 WCM162 Plasma 3134338044 C T KY p.R219Q 0 33 0.33 100 WCM162 Plasma 4 20535275 C TSLIT2 p.T590M 0 49 0.33913 115 WCM162 Plasma 4 36134981 C G ARAP2p.L1098F 0 38 0.173469 98 WCM162 Plasma 7 4304776 G T SDK1 p.E2134D 0 530.461078 167 WCM162 Plasma 8 143994104 C A CYP11B2 p.A414S 0 43 0.088496113 WCM162 Plasma 9 35649960 G C SIT1 p.S159C 0 40 0.151316 152 WCM162Plasma 11 118375359 A G KMT2A p.I2915V 0 83 0.362069 58 WCM162_Z1_1Tissue 1 169679606 T C SELL p.K32R 0 80 0.883333 60 WCM162_Z1_1 Tissue 1182443421 A G RGSL1 p.N392S 0 210 0.176471 170 WCM162_Z1_1 Tissue 118643323 G A TRIM66 p.R866* 0 68 0.385965 57 WCM162_Z1_1 Tissue 1201042709 G C CACNA1S p.P709A 0 76 0.260274 73 WCM162_Z1_1 Tissue 1210342624 G A TMEM52B p.R146H 0 159 0.238095 147 WCM162_Z1_1 Tissue 1213232864 A G KIAA1467 p.Q595R 0 91 0.591837 49 WCM162_Z1_1 Tissue 1494962975 A G SERPINA12 p.W214R 0 81 0.5 78 WCM162_Z1_1 Tissue 1499977099 C T CCNK p.R575W 0 61 0.104651 86 WCM162_Z1_1 Tissue 1531664300 C T KLF13 p.T222M 0 66 0.069767 43 WCM162_Z1_1 Tissue 162814185 C G SRRM2 p.S1219C 0 117 0.185484 124 WCM162_Z1_1 Tissue 16293582 C A ICMT p.A136S 0 57 0.065217 46 WCM162_Z1_1 Tissue 17 42463069G T ITGA2B p.Q142K 0 105 0.8 80 WCM162_Z1_1 Tissue 17 46608005 C A HOXB1p.A88S 0.009524 105 0.132353 136 WCM162_Z1_1 Tissue 17 79171676 T C AZI1p.S498G 0 104 0.354286 175 WCM162_Z1_1 Tissue 1 91405745 T C ZNF644p.K389R 0 162 0.112782 266 WCM162_Z1_1 Tissue 19 49686118 C T TRPM4p.A516V 0 42 0.288462 52 WCM162_Z1_1 Tissue 19 52909857 G T ZNF528p.D78Y 0 97 0.113924 79 WCM162_Z1_1 Tissue 19 5456584 G T ZNRF4 p.S361I0 61 0.123077 65 WCM162_Z1_1 Tissue 2 179482934 C T TTN p.E14110K 0 750.294872 78 WCM162_Z1_1 Tissue 22 38017651 A G GGA1 p.H186R 0 1700.229358 109 WCM162_Z1_1 Tissue 2 37473249 G C NDUFAF7 p.E283Q 0 560.209302 43 WCM162_Z1_1 Tissue 3 134338044 C T KY p.R219Q 0 184 0.156863102 WCM162_Z1_1 Tissue 3 45972765 A C FYCO1 p.V1350G 0 43 0.368421 38WCM162_Z1_1 Tissue 4 1360144 G A UVSSA p.D405N 0 52 0.179487 39WCM162_Z1_1 Tissue 4 185681621 G C ACSL1 p.H558D 0 63 0.282051 39WCM162_Z1_1 Tissue 4 20535275 C T SLIT2 p.T590M 0 69 0.27027 74WCM162_Z1_1 Tissue 4 36134981 C G ARAP2 p.L1098F 0 131 0.138614 101WCM162_Z1_1 Tissue 4 4204201 G A OTOP1 p.T235I 0 148 0.186275 102WCM162_Z1_1 Tissue 4 42467008 T C ATP8A1 p.N804D 0 159 0.34 100WCM162_Z1_1 Tissue 5 140773380 C T PCDHGA8 p.L334F 0 88 0.395833 48WCM162_Z1_1 Tissue 5 149500792 C T PDGFRB p.G813D 0 37 0.205882 34WCM162_Z1_1 Tissue 5 180472533 C G BTNL9 p.S15W 0 137 0.5 74 WCM162_Z1_1Tissue 5 482835 C T SLC9A3 p.R395H 0 318 0.339768 259 WCM162_Z1_1 Tissue5 63894231 G C RGS7BP p.R217S 0 84 0.087719 57 WCM162_Z1_1 Tissue 6100055043 C A PRDM13 p.P45T 0 139 0.148148 297 WCM162_Z1_1 Tissue 67230926 C G RREB1 p.P865R 0 104 0.116883 77 WCM162_Z1_1 Tissue 7121651490 C T PTPRZ1 p.T797M 0 150 0.09901 202 WCM162_Z1_1 Tissue 7148802170 G T ZNF425 p.Q265K 0 55 0.305882 85 WCM162_Z1_1 Tissue 731120231 G T ADCYAP1R1 p.W90L 0 76 0.186275 102 WCM162_Z1_1 Tissue 74304776 G T SDK1 p.E2134D 0 197 0.561856 194 WCM162_Z1_1 Tissue 8133141609 G T KCNQ3 p.T840K 0 35 0.058824 51 WCM162_Z1_1 Tissue 877617806 A G ZFHX4 p.I495V 0 93 0.45283 53 WCM162_Z1_1 Tissue 9100086128 C G CCDC180 p.F621L 0 185 0.366667 150 WCM162_Z1_1 Tissue 9113308556 C G SVEP1 p.S268T 0 97 0.054054 74 WCM162_Z1_1 Tissue 935649960 G C SIT1 p.S159C 0 76 0.20438 137 WCM162_Z1_1 Tissue 11 8643323G A TRIM66 p.R866* 0 68 0.059524 84 WCM162_Z9_1 Tissue 13 25882008 G TNUPL1 p.A58S 0 113 0.074766 107 WCM162_Z9_1 Tissue 13 39264439 A T FREM2p.E986D 0 35 0.096774 31 WCM162_Z9_1 Tissue 14 94962975 A G SERPINA12p.W214R 0 81 0.103448 87 WCM162_Z9_1 Tissue 17 42463069 G T ITGA2Bp.Q142K 0 105 0.178082 73 WCM162_Z9_1 Tissue 17 46608005 C A HOXB1p.A88S 0.009524 105 0.056604 106 WCM162_Z9_1 Tissue 18 28587094 T C DSC3p.D556G 0 62 0.06 50 WCM162_Z9_1 Tissue 19 12297713 G A ZNF136 p.G174R 056 0.140351 57 WCM162_Z9_1 Tissue 19 57176325 C T ZNF835 p.R81Q 0 1250.07438 121 WCM162_Z9_1 Tissue 2 102505261 A T MAP4K4 p.Y1167F 0 2180.055276 199 WCM162_Z9_1 Tissue 21 47402557 T G COL6A1 p.V36G 0 650.114286 70 WCM162_Z9_1 Tissue 2 3691060 C T COLEC11 p.R119C 0 720.057692 52 WCM162_Z9_1 Tissue 4 36134981 C G ARAP2 p.L1098F 0 1310.096491 114 WCM162_Z9_1 Tissue 7 4304776 G T SDK1 p.E2134D 0 1970.215596 218 WCM162_Z9_1 Tissue 9 100086128 C G CCDC180 p.F621L 0 1850.050847 177 WCM162_Z9_1 Tissue 13 48919317 T C RB1 p.L161P 0 600.342105 38 WCM163 Plasma 16 83813639 C G CDH13 p.P583R 0 70 0.327869 61WCM163 Plasma 17 41960701 G A MPP2 p.T82M 0 66 0.145833 96 WCM163 Plasma19 12059500 A C ZNF700 p.T221P 0 74 0.409524 105 WCM163 Plasma 1947844555 G A C5AR2 p.V167M 0 50 0.08 50 WCM163 Plasma 22 24562733 G TCABIN1 p.A1712S 0 60 0.306122 49 WCM163 Plasma 4 119252962 C G PRSS12p.E294Q 0 50 0.175439 57 WCM163 Plasma 4 144826647 A G GYPE p.I5T 0 580.223404 94 WCM163 Plasma 5 40937708 T G C7 p.F161L 0 74 0.137931 87WCM163 Plasma 7 79082393 C T MAGI2 p.V82M 0 77 0.168224 107 WCM163Plasma 8 3141672 A T CSMD1 p.F1384I 0 42 0.351852 54 WCM163 Plasma 1157068506 G A TNKS1BP1 p.R1661C 0 73 0.142857 42 WCM163_Z7_1 Tissue 1163258367 G A HRASLS5 p.P47L 0 171 0.342657 143 WCM163_Z7_1 Tissue 1342273224 C A VWA8 p.V1183F 0 43 0.935484 31 WCM163_Z7_1 Tissue 153675828 G A CPT2 p.R161Q 0 54 0.942857 35 WCM163_Z7_1 Tissue 1542028541 A G MGA p.N1360S 0 82 0.308642 81 WCM163_Z7_1 Tissue 1 62237255G A INADL p.S226N 0 78 0.222222 135 WCM163_Z7_1 Tissue 16 85015495 C TZDHHC7 p.E141K 0 88 0.088235 34 WCM163_Z7_1 Tissue 18 76754200 G A SALL3p.V737M 0 53 0.254902 51 WCM163_Z7_1 Tissue 19 12059500 A C ZNF700p.T221P 0 62 0.4375 96 WCM163_Z7_1 Tissue 19 19767554 A C ATP13A1p.L333R 0 83 0.31068 103 WCM163_Z7_1 Tissue 19 47844555 G A C5AR2p.V167M 0 71 0.425532 47 WCM163_Z7_1 Tissue 2 160637506 G A CD302 p.A61V0 68 0.395833 48 WCM163_Z7_1 Tissue 22 44579216 C A PARVG p.P3T 0 930.054545 55 WCM163_Z7_1 Tissue 3 32180154 C A GPD1L p.H101N 0 550.319149 47 WCM163_Z7_1 Tissue 4 119252962 C G PRSS12 p.E294Q 0 1220.090909 77 WCM163_Z7_1 Tissue 4 13606068 T A BOD1L1 p.N819I 0 780.191176 68 WCM163_Z7_1 Tissue 5 160047538 C A ATP10B p.E744D 0 1450.505435 184 WCM163_Z7_1 Tissue 5 173359456 G A CPEB4 p.R404H 0 980.248227 141 WCM163_Z7_1 Tissue 5 176304669 C T UNC5A p.R534C 0 600.265823 79 WCM163_Z7_1 Tissue 7 141424950 C T WEE2 p.P449L 0 1990.311881 202 WCM163_Z7_1 Tissue 7 94176475 G C CASD1 p.L567F 0 310.333333 39 WCM163_Z7_1 Tissue 8 3141672 A T CSMD1 p.F1384I 0 680.432836 67 WCM163_Z7_1 Tissue X 152845721 G A ATP2B3 p.G1210R 0 320.944444 36 WCM163_Z7_1 Tissue X 26212507 C A MAGEB6 p.Q182K 0 350.055556 54 WCM163_Z7_1 Tissue X 71895976 C A PHKA1 p.D188Y 0 530.076923 78 WCM163_Z7_1 Tissue 1 112031565 T C ADORA3 p.Y180C 0 380.096774 62 WCM164 Plasma 12 72092752 A G TMEM19 p.Y237C 0 41 0.09638683 WCM164 Plasma 17 7577574 T C TP53 p.Y236C 0 33 0.109375 64 WCM164Plasma 10 135086499 G A ADAM8 p.R200C 0 64 0.098039 51 WCM164_X1_1Tissue 10 27324385 G T ANKRD26 p.S998R 0 64 0.12381 105 WCM164_X1_1Tissue 1 22816663 G T ZBTB40 p.L74F 0 52 0.090909 33 WCM164_X1_1 Tissue12 49176698 C T ADCY6 p.A174T 0 55 0.180556 72 WCM164_X1_1 Tissue 128083127 T C SLC2A3 p.S208G 0 165 0.07027 185 WCM164_X1_1 Tissue 13114778646 T C RASA3 p.N495S 0 120 0.463415 123 WCM164_X1_1 Tissue 13114778664 G A RASA3 p.P489L 0 109 0.478261 115 WCM164_X1_1 Tissue 13115009458 C G CDC16 p.T254S 0 108 0.139241 79 WCM164_X1_1 Tissue 14101010278 G A BEGAIN p.R90C 0 103 0.325397 126 WCM164_X1_1 Tissue 143777674 G A TIE1 p.S501N 0 190 0.375 168 WCM164_X1_1 Tissue 17 7577574T C TP53 p.Y236C 0 195 0.517442 172 WCM164_X1_1 Tissue 20 55027649 G TCASS4 p.E473* 0 198 0.165217 115 WCM164_X1_1 Tissue 2 158412656 T CACVR1C p.K165E 0 32 0.135135 37 WCM164_X1_1 Tissue 2 33623439 G A LTBP1p.E1665K 0 48 0.326531 49 WCM164_X1_1 Tissue 5 72469209 C A TMEM174p.L47M 0 191 0.116279 172 WCM164_X1_1 Tissue 6 91278290 G T MAP3K7p.A95D 0 61 0.153846 91 WCM164_X1_1 Tissue 7 150839597 C T AGAP3 p.L386F0 96 0.150685 146 WCM164_X1_1 Tissue 7 76029752 C T SRCRB4D p.R109Q 0 500.142857 49 WCM164_X1_1 Tissue 9 123903763 T G CNTRL p.V863G 0 1260.179012 162 WCM164_X1_1 Tissue X 139587119 G T SOX3 p.A36D 0 39 0.2 40WCM164_X1_1 Tissue 15 43712787 T C TP53BP1 p.D1461G 0 33 0.090909 55WCM169 Plasma 15 43748917 C G TP53BP1 p.S625T 0 33 0.105263 57 WCM169Plasma 15 43748918 T C TP53BP1 p.S625G 0 32 0.105263 57 WCM169 Plasma 1543783909 C G TP53BP1 p.S105T 0 53 0.090909 77 WCM169 Plasma 15 43783910T C TP53BP1 p.S105G 0 53 0.090909 77 WCM169 Plasma 11 128842742 C AARHGAP32 p.R1206L 0 58 0.096774 31 WCM169_X1_1 Tissue 11 55563663 G TOR5D14 p.C211F 0 67 0.052632 57 WCM169_X1_1 Tissue 11 66083529 G T CD248p.Q324K 0 98 0.078947 76 WCM169_X1_1 Tissue 12 113303281 G T RPH3Ap.C98F 0 77 0.065217 92 WCM169_X1_1 Tissue 12 54448685 C A HOXC4 p.T164N0 126 0.061224 49 WCM169_X1_1 Tissue 14 102661325 G T WDR20 p.Q100H 0 590.081081 37 WCM169_X1_1 Tissue 14 103336598 G T TRAF3 p.K20N 0 700.073171 82 WCM169_X1_1 Tissue 16 15729680 C A KIAA0430 p.G222C 0 1220.067416 89 WCM169_X1_1 Tissue 19 15302421 C T NOTCH3 p.A284T 0 580.084507 71 WCM169_X1_1 Tissue 19 17722640 C A UNC13A p.G1528V 0 1370.054795 146 WCM169_X1_1 Tissue 19 6697381 C A C3 p.G924C 0 72 0.08 75WCM169_X1_1 Tissue 3 12422946 G T PPARG p.A146S 0 155 0.0625 64WCM169_X1_1 Tissue 3 152163110 G T MBNL1 p.E197* 0 56 0.061224 49WCM169_X1_1 Tissue 3 184039299 G T EIF4G1 p.E309D 0 88 0.096774 31WCM169_X1_1 Tissue 5 141331076 G T PCDH12 p.A987D 0 126 0.070175 114WCM169_X1_1 Tissue 7 100817863 C A NAT16 p.G76C 0 50 0.077922 77WCM169_X1_1 Tissue 7 148801389 G A ZNF425 p.P525L 0 57 0.0625 48WCM169_X1_1 Tissue 7 44149644 G A AEBP1 p.R394H 0 101 0.117647 51WCM169_X1_1 Tissue X 12701695 G A FRMPD4 p.G188S 0 101 0.052174 115WCM169_X1_1 Tissue 19 58564971 G A ZSCAN1 p.R260H 0 32 0.092105 76WCM170 Plasma 7 94047838 G A COL1A2 p.G667S 0 33 0.074074 81 WCM170Plasma 9 32633273 C T TAF1L p.A769T 0 34 0.06383 94 WCM170 Plasma 10101823439 C T CPN1 p.G268D 0 60 0.081081 37 WCM170_Z1_1 Tissue 1048413661 C T GDF2 p.V403I 0 128 0.191489 94 WCM170_Z1_1 Tissue 106258698 G C PFKFB3 p.E132D 0 242 0.238281 256 WCM170_Z1_1 Tissue 1075562812 G A NDST2 p.R781C 0 76 0.333333 108 WCM170_Z1_1 Tissue 115679397 G A FHAD1 p.E805K 0 199 0.115385 182 WCM170_Z1_1 Tissue 116150467 G T OR56B3P p.D210Y 0 243 0.137725 167 WCM170_Z1_1 Tissue 1172558877 G A SUCO p.G879E 0 60 0.06 50 WCM170_Z1_1 Tissue 1 179521762 TG NPHS2 p.E283D 0 126 0.181034 116 WCM170_Z1_1 Tissue 1 20416368 C TPLA2G5 p.A91V 0 191 0.16129 155 WCM170_Z1_1 Tissue 1 223983752 G ATP53BP2 p.P830L 0 86 0.302083 96 WCM170_Z1_1 Tissue 12 27916182 G TMANSC4 p.T171K 0 117 0.090909 88 WCM170_Z1_1 Tissue 12 56992988 G ABAZ2A p.S1778L 0 112 0.117978 178 WCM170_Z1_1 Tissue 14 102506595 T GDYNC1H1 p.F3905V 0 179 0.18797 133 WCM170_Z1_1 Tissue 16 20492232 G AACSM2A p.V500I 0 38 0.297297 37 WCM170_Z1_1 Tissue 1 62593744 C T INADLp.A1715V 0 167 0.056452 124 WCM170_Z1_1 Tissue 19 58564971 G A ZSCAN1p.R260H 0 187 0.166667 126 WCM170_Z1_1 Tissue 21 27102057 C T ATP5Jp.V17I 0 228 0.191489 141 WCM170_Z1_1 Tissue 2 229890413 C T PID1p.G230R 0 70 0.244275 131 WCM170_Z1_1 Tissue 3 127358327 G T PODXL2p.E104* 0 157 0.178571 140 WCM170_Z1_1 Tissue 4 159782540 G T FNIP2p.V399L 0 87 0.050847 59 WCM170_Z1_1 Tissue 4 39347026 T A RFC1 p.D68V 098 0.078125 64 WCM170_Z1_1 Tissue 5 134060701 C A SEC24A p.Q1067K 0 790.083333 72 WCM170_Z1_1 Tissue 7 150695718 C A NOS3 p.Q256K 0 2210.386139 202 WCM170_Z1_1 Tissue 7 57529622 G T ZNF716 p.M485I 0 1260.157895 133 WCM170_Z1_1 Tissue 7 73280028 C T WBSCR28 p.T208I 0 1280.142857 161 WCM170_Z1_1 Tissue 9 127316832 G A NR6A1 p.R54W 0 56 0.062548 WCM170_Z1_1 Tissue 9 32633273 C T TAF1L p.A769T 0 63 0.083333 48WCM170_Z1_1 Tissue 10 48413661 C T GDF2 p.V403I 0 128 0.32287 223WCM170_Z16_1 Tissue 10 75562812 G A NDST2 p.R781C 0 76 0.197674 172WCM170_Z16_1 Tissue 11 112101358 G T PTS p.A66S 0 61 0.068182 44WCM170_Z16_1 Tissue 1 15679397 G A FHAD1 P.E805K 0 199 0.366492 191WCM170_Z16_1 Tissue 11 6150467 G T OR56B3P p.D210Y 0 243 0.412556 223WCM170_Z16_1 Tissue 12 111884588 C G SH2B3 p.S255C 0 50 0.389474 95WCM170_Z16_1 Tissue 12 132549292 C T EP400 p.P2841L 0 104 0.230263 152WCM170_Z16_1 Tissue 1 223983752 G A TP53BP2 p.P830L 0 86 0.357143 98WCM170_Z16_1 Tissue 12 50232759 G C BCDIN3D p.P92A 0 48 0.274194 62WCM170_Z16_1 Tissue 12 56992988 G A BAZ2A p.S1778L 0 112 0.305164 213WCM170_Z16_1 Tissue 15 43476731 T A TMEM62 p.S627T 0 184 0.131579 114WCM170_Z16_1 Tissue 16 20492232 G A ACSM2A p.V500I 0 38 0.402985 67WCM170_Z16_1 Tissue 16 67680412 G T RLTPR p.S153I 0 73 0.086957 69WCM170_Z16_1 Tissue 18 21708929 C A TTC39C p.N500K 0 60 0.74359 39WCM170_Z16_1 Tissue 19 18170889 G T IL12RB1 p.Q600K 0 160 0.348 250WCM170_Z16_1 Tissue 19 58564971 G A ZSCAN1 p.R260H 0 187 0.371951 164WCM170_Z16_1 Tissue 20 36767844 C G TGM2 p.D438H 0 263 0.231707 492WCM170_Z16_1 Tissue 21 27102057 C T ATP5J p.V17I 0 228 0.358621 145WCM170_Z16_1 Tissue 2 186656538 C T FSIP2 p.P1559S 0 106 0.479167 48WCM170_Z16_1 Tissue 2 229890413 C T PID1 p.G230R 0 70 0.429577 142WCM170_Z16_1 Tissue 2 29295516 G A C2orf71 p.Q538* 0 51 0.053571 56WCM170_Z16_1 Tissue 3 127358327 G T PODXL2 p.E104* 0 157 0.406417 187WCM170_Z16_1 Tissue 3 44684647 G C ZNF197 p.E675D 0 44 0.390244 41WCM170_Z16_1 Tissue 5 52183702 G T ITGA1 p.V277F 0 98 0.0625 48WCM170_Z16_1 Tissue 7 150695718 C A NOS3 p.Q256K 0 221 0.354545 220WCM170_Z16_1 Tissue 7 57529622 G T ZNF716 p.M485I 0 126 0.354839 124WCM170_Z16_1 Tissue 9 32633273 C T TAF1L p.A769T 0 63 0.39726 73WCM170_Z16_1 Tissue 10 1038445 C A GTPBP4 p.T22K 0 48 0.06383 47WCM172_X1_1 Tissue 1 11562050 C T PTCHD2 p.S334L 0 90 0.148649 74WCM172_X1_1 Tissue 1 152127702 C T RPTN p.G625R 0 110 0.275449 167WCM172_X1_1 Tissue 11 64806238 G A SNX15 p.A287T 0 275 0.248062 258WCM172_X1_1 Tissue 12 109853384 G A MYO1H p.R513Q 0 144 0.382199 191WCM172_X1_1 Tissue 1 224477260 G C NVL P.P501A 0 62 0.102941 68WCM172_X1_1 Tissue 1 230904957 C T CAPN9 p.T246M 0 88 0.521739 92WCM172_X1_1 Tissue 1 27684918 C T MAP3K6 p.R923Q 0 170 0.296053 152WCM172_X1_1 Tissue 14 32903012 G A AKAP6 p.V105I 0 99 0.235294 119WCM172_X1_1 Tissue 16 2134329 G A TSC2 p.R1369Q 0 35 0.054545 55WCM172_X1_1 Tissue 16 9009316 G A USP7 p.R325C 0 80 0.066667 90WCM172_X1_1 Tissue 19 49110516 G A SPACA4 p.R94H 0 80 0.063492 63WCM172_X1_1 Tissue 2 32419022 C T SLC30A6 p.R156W 0 47 0.065217 46WCM172_X1_1 Tissue 2 9607902 T G CPSF3 p.L618R 0 111 0.058824 119WCM172_X1_1 Tissue 3 132363723 G T ACAD11 p.P56Q 0 62 0.070423 71WCM172_X1_1 Tissue 3 44853755 G T KIF15 p.E751* 0 246 0.272388 268WCM172_X1_1 Tissue 6 112462693 A C LAMA4 p.Y894D 0 60 0.418605 43WCM172_X1_1 Tissue 6 33177715 G T RING1 p.R88L 0 51 0.306452 62WCM172_X1_1 Tissue 6 42974348 C T PPP2R5D p.R85* 0 130 0.21229 179WCM172_X1_1 Tissue 6 75912454 A C COL12A1 p.S19A 0 179 0.364641 181WCM172_X1_1 Tissue 9 94486196 G T ROR2 p.S860R 0 235 0.310714 280WCM172_X1_1 Tissue 10 38121401 G T ZNF248 p.D294E 0 172 0.20202 99WCM172_X2_1 Tissue 1 11562050 C T PTCHD2 p.S334L 0 90 0.371795 78WCM172_X2_1 Tissue 1 152127702 C T RPTN p.G625R 0 110 0.581818 55WCM172_X2_1 Tissue 11 64806238 G A SNX15 p.A287T 0 275 0.392265 181WCM172_X2_1 Tissue 11 76892428 G C MYO7A p.E899D 0 208 0.070796 113WCM172_X2_1 Tissue 12 109853384 G A MYO1H p.R513Q 0 144 0.420455 88WCM172_X2_1 Tissue 1 224477260 G C NVL p.P501A 0 62 0.326531 49WCM172_X2_1 Tissue 1 230904957 C T CAPN9 p.T246M 0 88 0.892473 93WCM172_X2_1 Tissue 12 49440489 G A KMT2D p.R1441C 0 118 0.061224 49WCM172_X2_1 Tissue 12 57559911 C T LRP1 p.R906W 0 58 0.070175 57WCM172_X2_1 Tissue 1 27684918 C T MAP3K6 p.R923Q 0 170 0.561224 98WCM172_X2_1 Tissue 14 32903012 G A AKAP6 p.V105I 0 99 0.333333 81WCM172_X2_1 Tissue 14 76437953 A T TGFB3 p.L154* 0 31 0.091837 98WCM172_X2_1 Tissue 18 19116140 C T ESCO1 p.E684K 0 39 0.066667 45WCM172_X2_1 Tissue 2 37513372 C G PRKD3 p.Q286H 0 73 0.210526 76WCM172_X2_1 Tissue 3 44853755 G T KIF15 p.E751* 0 246 0.320611 262WCM172_X2_1 Tissue 6 112462693 A C LAMA4 p.Y894D 0 60 0.666667 36WCM172_X2_1 Tissue 6 136599171 C T BCLAF1 p.R283Q 0 218 0.180645 155WCM172_X2_1 Tissue 6 33177715 G T RING1 p.R88L 0 51 0.315789 76WCM172_X2_1 Tissue 6 42974348 C T PPP2R5D p.R85* 0 130 0.363636 99WCM172_X2_1 Tissue 6 75912454 A C COL12A1 p.S19A 0 179 0.430303 165WCM172_X2_1 Tissue 7 100682877 C A MUC17 p.A2727D 0 232 0.069124 217WCM172_X2_1 Tissue 7 16815999 T A TSPAN13 p.F76Y 0 68 0.072464 69WCM172_X2_1 Tissue 9 94486196 G T ROR2 p.S860R 0 235 0.52459 305WCM172_X2_1 Tissue 11 108160489 G T ATM p.R1466L 0 36 0.088889 45 WCM176Plasma 11 108224582 A G ATM p.T2921A 0 44 0.061224 49 WCM176 Plasma 1161123830 G T UFC1 p.V15L 0 50 0.096774 31 WCM176 Plasma 12 11061365 G ATAS2R13 p.S178L 0 42 0.085714 35 WCM176 Plasma 14 93940602 G A UNC79p.R104Q 0 53 0.078947 38 WCM176 Plasma 15 43712787 T C TP53BP1 p.D1461G0 35 0.371429 35 WCM176 Plasma 15 43748441 A C TP53BP1 p.S784A 0 390.075 40 WCM176 Plasma 15 43749164 T C TP53BP1 p.T543A 0 40 0.157895 38WCM176 Plasma 15 43749223 C G TP53BP1 p.S523T 0 43 0.093023 43 WCM176Plasma 15 43749224 T C TP53BP1 p.S523G 0 44 0.090909 44 WCM176 Plasma 1543769827 T C TP53BP1 p.T302A 0 72 0.16 50 WCM176 Plasma 15 43769897 C ATP53BP1 p.Q278H 0 50 0.153846 52 WCM176 Plasma 15 90129030 G T TICRRp.R423L 0 35 0.078947 38 WCM176 Plasma 17 73045382 G T KCTD2 p.R136L 045 0.090909 33 WCM176 Plasma 19 46916046 C T CCDC8 p.V8I 0 35 0.08108137 WCM176 Plasma 22 28195045 C A MN1 p.G496V 0 49 0.090909 33 WCM176Plasma 3 136035879 G T PCCB p.V355F 0 58 0.071429 42 WCM176 Plasma 3172232713 C T TNFSF10 p.E70K 0 33 0.071429 42 WCM176 Plasma 5 140202861C T PCDHA5 p.R501C 0 67 0.088235 34 WCM176 Plasma 9 78965788 C G PCSK5p.L1644V 0 42 0.096774 31 WCM176 Plasma 11 66373322 T G CCS p.L274R 0211 0.35533 197 WCM176_Z1_1 Tissue 12 131488739 G A GPR133 p.V385M 0 640.08642 81 WCM176_Z1_1 Tissue 12 65085348 G C RASSF3 p.E186Q 0 1340.361905 105 WCM176_Z1_1 Tissue 15 75890986 A G SNUPN p.Y266H 0 1780.443662 142 WCM176_Z1_1 Tissue 19 1428920 G A DAZAP1 p.R209Q 0 1980.542484 153 WCM176_Z1_1 Tissue 22 24698332 A G SPECC1L p.T45A 0 2820.398524 271 WCM176_Z1_1 Tissue 3 184144447 C T RP11- p.P37L 0 690.416667 48 WCM176_Z1_1 Tissue 433C9.2 5 40959677 C T C7 p.T539M 0 1000.398305 118 WCM176_Z1_1 Tissue 6 43410876 G A ABCC10 p.A799T 0 830.392157 102 WCM176_Z1_1 Tissue 9 134361525 C T PRRC2B p.R1938W 0 4140.41623 382 WCM176_Z1_1 Tissue 10 103296387 G T BTRC p.R518S 0 730.055046 109 WCM183 Plasma 10 104174846 C T PSD p.D300N 0 44 0.152174 92WCM183 Plasma 10 111860436 G A ADD3 p.V9M 0 48 0.401869 107 WCM183Plasma 10 17373496 T G ST8SIA6 p.N145H 0 62 0.067416 89 WCM183 Plasma 1048388191 T G RBP3 p.Q896P 0 39 0.234375 64 WCM183 Plasma 10 93244314 T GHECTD2 p.I291S 0 69 0.121951 123 WCM183 Plasma 11 1651119 C T KRTAP5-5p.R17C 0 43 0.055556 90 WCM183 Plasma 11 46897468 C T LRP4 p.G1196R 0 570.361111 108 WCM183 Plasma 11 47370035 G A MYBPC3 p.R238C 0 31 0.30120583 WCM183 Plasma 1 151239806 A G PSMD4 p.E374G 0 42 0.173077 104 WCM183Plasma 1 151372091 G A PSMB4 p.G10R 0 35 0.333333 51 WCM183 Plasma 1156916546 C G ARHGEF11 p.V828L 0 37 0.305085 59 WCM183 Plasma 1162384796 A G B3GAT3 p.V94A 0 40 0.22973 74 WCM183 Plasma 11 69518088 T GFGF19 p.K93Q 0 54 0.053191 94 WCM183 Plasma 1 176526160 T A PAPPA2p.S234R 0 54 0.25 100 WCM183 Plasma 11 94759539 C G KDM4E p.P273R 0 370.058252 103 WCM183 Plasma 12 110760817 G T ATP2A2 p.D162Y 0 49 0.386139101 WCM183 Plasma 12 133398588 C T GOLGA3 p.V43I 0 34 0.178571 84 WCM183Plasma 1 230827164 G A COG2 p.V657M 0 35 0.356322 87 WCM183 Plasma 1235643456 A G B3GALNT2 p.F189L 0 54 0.15 100 WCM183 Plasma 1 237777529 GT RYR2 p.G1701C 0 41 0.194915 118 WCM183 Plasma 1 238050757 C G ZP4p.D220H 0 42 0.122449 98 WCM183 Plasma 1 247059181 G C AHCTF1 p.S557C 060 0.179245 106 WCM183 Plasma 12 52162740 A G SCN8A p.Q998R 0 500.121739 115 WCM183 Plasma 12 57111005 C G NACA p.A1437P 0 39 0.18032861 WCM183 Plasma 12 77424091 C G E2F7 p.K468N 0 36 0.113402 97 WCM183Plasma 13 25275019 G A ATP12A p.V614M 0 75 0.569231 130 WCM183 Plasma 138155549 T C C1orf109 p.T2A 0 42 0.272727 55 WCM183 Plasma 1 45278702 AC BTBD19 p.E150A 0 36 0.173077 52 WCM183 Plasma 14 66208947 G A FUT8p.R516Q 0 64 0.642105 95 WCM183 Plasma 14 73822431 C A NUMB p.R10I 0 470.275362 69 WCM183 Plasma 14 75248260 A C YLPM1 p.N505T 0 40 0.128571 70WCM183 Plasma 14 75515587 G T MLH3 p.L258I 0 39 0.053333 75 WCM183Plasma 14 75515589 C T MLH3 p.R257K 0 40 0.054054 74 WCM183 Plasma 1477722884 G A TMEM63C p.V746M 0 34 0.556962 79 WCM183 Plasma 14 94582169C T IFI27 p.A55V 0 49 0.241379 87 WCM183 Plasma 15 71184269 G T THAP10p.L115I 0 54 0.337209 86 WCM183 Plasma 15 83456043 G C FSD2 p.H34D 0 400.216495 97 WCM183 Plasma 16 68289728 T C PLA2G15 p.Y188H 0 45 0.37878866 WCM183 Plasma 16 9857926 G A GRIN2A p.R1159C 0 61 0.255556 90 WCM183Plasma 1 70502205 C T LRRC7 p.S691L 0 43 0.267606 71 WCM183 Plasma 172275545 G A SGSM2 p.G502S 0 84 0.32 125 WCM183 Plasma 17 47696688 T CSPOP p.Y87C 0 34 0.417722 79 WCM183 Plasma 17 49270329 C A MBTD1 p.D502Y0 66 0.311927 109 WCM183 Plasma 17 56332315 C A LPO p.L417M 0 310.141304 92 WCM183 Plasma 17 67092782 A T ABCA6 p.I1094N 0 93 0.186207145 WCM183 Plasma 17 7133223 C G DVL2 p.R187P 0 34 0.20339 59 WCM183Plasma 17 74163840 C A RNF157 p.S112I 0 54 0.225 120 WCM183 Plasma 1776424614 C T DNAH17 p.E4189K 0 31 0.272727 88 WCM183 Plasma 17 8791542 AT PIK3R5 p.V521D 0 58 0.289474 76 WCM183 Plasma 18 210454 T C USP14p.S432P 0 54 0.214286 84 WCM183 Plasma 18 51052995 C G DCC p.L1374V 0 360.235294 85 WCM183 Plasma 1 86909572 C T CLCA2 p.Q531* 0 66 0.2 100WCM183 Plasma 19 12126943 T C ZNF433 p.T247A 0 78 0.369748 119 WCM183Plasma 19 16006322 C T CYP4F2 p.A113T 0 32 0.238095 84 WCM183 Plasma 1917379781 G A BABAM1 p.A56T 0 81 0.346154 104 WCM183 Plasma 19 5595407 CG SAPB2 p.Q628H 0 40 0.213115 61 WCM183 Plasma 19 56126233 C T ZNF865p.R417C 0 32 0.1875 32 WCM183 Plasma 19 9068625 C T MUC16 p.R6274H 0 560.333333 108 WCM183 Plasma 20 168682 C G DEFB128 p.E43Q 0 67 0.153846130 WCM183 Plasma 20 2297755 G C TGM3 p.W237C 0 48 0.160377 106 WCM183Plasma 20 2845674 C G VPS16 p.Y659* 0 56 0.153153 111 WCM183 Plasma 2035207220 C G TGIF2 p.L15V 0 32 0.257576 66 WCM183 Plasma 20 3683989 G TSIGLEC1 p.Y361* 0 33 0.461538 91 WCM183 Plasma 20 42223432 C A IFT52p.L32I 0 57 0.142857 105 WCM183 Plasma 20 43090836 C A C20orf62 p.V68F 032 0.283951 81 WCM183 Plasma 21 19642347 C T IMPRSS15 p.R1000H 0 680.240876 137 WCM183 Plasma 21 19726056 G T IMPRSS15 p.N335K 0 740.119403 134 WCM183 Plasma 2 144460998 C A ARHGAP15 p.D383E 0 430.051948 77 WCM183 Plasma 2 160621143 A C 7-Mar p.N672H 0 68 0.11215 107WCM183 Plasma 2 190557142 C G ANKAR p.Q401E 0 50 0.445946 74 WCM183Plasma 2 198540059 C G RFTN2 p.D42H 0 55 0.197802 91 WCM183 Plasma 2206036971 G C PARD3B p.V553L 0 52 0.350515 97 WCM183 Plasma 2 207615712G T MDH1B p.A333D 0 81 0.534483 116 WCM183 Plasma 2 228882435 C G SPHKAPp.K1045N 0 33 0.3 60 WCM183 Plasma 2 27800725 G C C2orf16 p.G429A 0 340.266667 105 WCM183 Plasma 2 32693143 C T BIRC6 p.A1915V 0 47 0.072727110 WCM183 Plasma 2 68364558 C T WDR92 p.S214N 0 51 0.057143 105 WCM183Plasma 2 71744167 C T DYSF p.R302W 0 58 0.539823 113 WCM183 Plasma 299256375 A T MGAT4A p.H406Q 0 31 0.1875 80 WCM183 Plasma 3 118913124 G AUPK1B p.R176Q 0 51 0.542056 107 WCM183 Plasma 3 121187218 A T POLQp.M2260K 0 59 0.063636 110 WCM183 Plasma 3 121212330 G T POLQ p.F839L 089 0.172662 139 WCM183 Plasma 3 121415555 A G GOLGB1 p.L1267S 0 610.145631 103 WCM183 Plasma 3 167039938 T C ZBBX p.Y317C 0 59 0.234043141 WCM183 Plasma 3 190936699 C G OSTN p.S89C 0 52 0.109375 128 WCM183Plasma 3 27465595 T C SLC4A7 p.K391R 0 45 0.113636 88 WCM183 Plasma 331725217 C A OSBPL10 p.E545D 0 47 0.164948 97 WCM183 Plasma 3 52821094 AC ITIH1 p.T623P 0 35 0.315068 73 WCM183 Plasma 3 93603590 G C PROS1p.Q492E 0 51 0.126126 111 WCM183 Plasma 4 16597439 C T LDB2 p.D99N 0 610.050505 99 WCM183 Plasma 4 40824024 G C APBB2 p.S658C 0 48 0.294737 95WCM183 Plasma 4 74283848 C T ALB p.T341M 0 49 0.35 80 WCM183 Plasma 5148998522 G C ARHGEF37 p.D271H 0 43 0.156627 83 WCM183 Plasma 5159996528 T A ATP10B p.T1305S 0 47 0.295652 115 WCM183 Plasma 5 35910017A G CAPSL p.F159S 0 65 0.184466 103 WCM183 Plasma 5 76330271 G T AGGF1p.R80L 0 50 0.329787 94 WCM183 Plasma 5 79837548 T C FAM151B p.L243P 062 0.218182 110 WCM183 Plasma 5 94253672 C T MCTP1 p.G427S 0 41 0.27941268 WCM183 Plasma 6 102376391 G A GRIK2 p.A657T 0 63 0.35 100 WCM183Plasma 6 121655438 C T TBC1D32 p.D47N 0 67 0.150685 73 WCM183 Plasma 6129634205 G C LAMA2 p.C1125S 0 35 0.108434 83 WCM183 Plasma 6 152652697G A SYNE1 p.P4375S 0 44 0.181818 121 WCM183 Plasma 6 56504349 T G DSTp.T709P 0 36 0.2 90 WCM183 Plasma 6 7605635 T C SNRNP48 p.I241T 0 530.1875 112 WCM183 Plasma 7 100636331 C G MUC12 p.S972R 0 77 0.144 125WCM183 Plasma 7 100678290 G C MUC17 p.S1198T 0 49 0.19084 131 WCM183Plasma 7 107718670 G T LAMB4 p.S660Y 0 43 0.277108 83 WCM183 Plasma 7117227838 G A CFTR p.G544S 0 55 0.549451 91 WCM183 Plasma 7 117235010 CA CFTR p.S839R 0 39 0.306306 111 WCM183 Plasma 7 142961754 G A GSTK1p.V90M 0 56 0.113043 115 WCM183 Plasma 7 150553798 C G AOC1 p.Y80* 0 560.396825 126 WCM183 Plasma 8 100821613 T A VPS13B p.I2676N 0 74 0.149701167 WCM183 Plasma 8 118541004 A G MED30 p.K98E 0 77 0.051613 155 WCM183Plasma 8 124998311 G C FER1L6 p.V472L 0 62 0.11194 134 WCM183 Plasma 8143846118 T A LYNX1 p.M101L 0 54 0.113333 150 WCM183 Plasma 8 146156387T A ZNF16 p.T596S 0 65 0.113333 150 WCM183 Plasma 8 2857600 C A CSMD1p.G2696C 0 40 0.263158 57 WCM183 Plasma 9 109689821 A T ZNF462 p.I1210F0 47 0.206897 87 WCM183 Plasma 9 116930056 T G COL27A1 p.F74C 0 600.17037 135 WCM183 Plasma 9 124929180 G A MORN5 p.G61R 0 31 0.311828 93WCM183 Plasma 9 95078261 G A NOL8 p.P216S 0 52 0.459854 137 WCM183Plasma 9 98221932 G A PTCH1 p.P946L 0 56 0.231481 108 WCM183 Plasma 998643423 A C ERCC6L2 p.K118Q 0 59 0.565574 122 WCM183 Plasma X 26212711G A MAGEB6 p.V250I 0 51 0.578125 64 WCM183 Plasma 10 103919727 G T NOLC1p.A312S 0 85 0.155844 77 WCM183_Z4_1 Tissue 10 104174846 C T PSD p.D300N0.008333 120 0.23741 139 WCM183_Z4_1 Tissue 10 1230887 C T ADARB2p.A653T 0 155 0.5 90 WCM183_Z4_1 Tissue 10 48388191 T G RBP3 p.Q896P 0128 0.457627 59 WCM183_Z4_1 Tissue 10 73572594 G C CDH23 p.E3199Q 0 1940.195122 205 WCM183_Z4_1 Tissue 11 46897468 C T LRP4 p.G1196R 0 2060.46087 115 WCM183_Z4_1 Tissue 11 47370035 G A MYBPC3 p.R238C 0 960.2625 80 WCM183_Z4_1 Tissue 1 151239806 A G PSMD4 p.E374G 0 2830.238095 252 WCM183_Z4_1 Tissue 1 151372091 G A PSMB4 p.G10R 0 1260.587156 109 WCM183_Z4_1 Tissue 11 63059031 A G SLC22A10 p.Y141C 0 710.204082 98 WCM183_Z4_1 Tissue 11 64121627 G A CCDC88B p.E1362K 0 1690.318182 220 WCM183_Z4_1 Tissue 1 176526160 T A PAPPA2 p.S234R 0 690.194444 108 WCM183_Z4_1 Tissue 12 110760817 G T ATP2A2 p.D162Y 0 1410.194286 175 WCM183_Z4_1 Tissue 12 113826415 A G PLBD2 p.K585R 0 2010.789474 190 WCM183_Z4_1 Tissue 12 122750898 G T VPS33A p.R20S 0 52 0.0650 WCM183_Z4_1 Tissue 12 133398588 C T GOLGA3 p.V43I 0 55 0.265306 49WCM183_Z4_1 Tissue 1 230827164 G A COG2 p.V657M 0 53 0.480769 52WCM183_Z4_1 Tissue 12 32134263 G C KIAA1551 p.R125T 0 141 0.192308 130WCM183_Z4_1 Tissue 1 237777529 G T RYR2 p.G1701C 0 216 0.269663 267WCM183_Z4_1 Tissue 1 238050757 C G ZP4 p.D220H 0.009346 107 0.188976 127WCM183_Z4_1 Tissue 1 247059181 G C AHCTF1 p.S557C 0 56 0.113636 44WCM183_Z4_1 Tissue 12 52162740 A G SCN8A p.Q998R 0 355 0.226257 358WCM183_Z4_1 Tissue 12 57111005 C G NACA p.A1437P 0 154 0.165714 175WCM183_Z4_1 Tissue 12 57619421 C T NXPH4 p.P273L 0 107 0.346154 78WCM183_Z4_1 Tissue 12 66786226 C G GRIP1 p.G724R 0 171 0.266304 184WCM183_Z4_1 Tissue 12 69090622 T G NUP107 p.F158V 0 157 0.225806 124WCM183_Z4_1 Tissue 12 7354909 C T PEX5 p.Q239* 0 133 0.158333 120WCM183_Z4_1 Tissue 12 77424091 C G E2F7 p.K468N 0 50 0.353846 65WCM183_Z4_1 Tissue 13 25275019 G A ATP12A p.V614M 0 111 0.509804 102WCM183_Z4_1 Tissue 14 27064727 G A NOVA1 p.P57S 0 97 0.136 125WCM183_Z4_1 Tissue 14 33147602 G T AKAP6 p.S939I 0 52 0.06 50WCM183_Z4_1 Tissue 14 66208947 G A FUT8 p.R516Q 0 145 0.712963 108WCM183_Z4_1 Tissue 14 70925489 G A ADAM21 p.V425I 0 53 0.333333 36WCM183_Z4_1 Tissue 14 73822431 C A NUMB p.R10I 0 82 0.481481 54WCM183_Z4_1 Tissue 14 75248260 A C YLPM1 p.N505T 0 86 0.160714 56WCM183_Z4_1 Tissue 15 71184269 G T THAP10 p.L115I 0 81 0.947368 57WCM183_Z4_1 Tissue 16 20360281 C A UMOD p.E114D 0 46 0.266667 45WCM183_Z4_1 Tissue 16 66919683 C T PDP2 p.P499L 0 107 0.357143 56WCM183_Z4_1 Tissue 16 68289728 T C PLA2G15 p.Y188H 0 219 0.471264 87WCM183_Z4_1 Tissue 16 74640905 G C GLG1 p.L30V 0 70 0.297297 37WCM183_Z4_1 Tissue 16 9857926 G A GRIN2A p.R1159C 0 43 0.235294 34WCM183_Z4_1 Tissue 17 28530317 C T SLC6A4 p.R564Q 0 52 0.149254 67WCM183_Z4_1 Tissue 17 33495121 C A UNC45B p.A398D 0 71 0.428571 49WCM183_Z4_1 Tissue 17 4449158 C G MYBBP1A p.S635T 0 179 0.254386 114WCM183_Z4_1 Tissue 17 47696688 T C SPOP p.Y87C 0 40 0.30303 66WCM183_Z4_1 Tissue 17 49270329 C A MBTD1 p.D502Y 0 147 0.608108 148WCM183_Z4_1 Tissue 17 56332315 C A LPO p.L417M 0 127 0.196078 153WCM183_Z4_1 Tissue 17 62553818 G C SMURF2 p.H447D 0 93 0.124031 129WCM183_Z4_1 Tissue 17 74382357 C A SPHK1 p.D73E 0 108 0.495495 111WCM183_Z4_1 Tissue 17 76455115 C A DNAH17 p.E3272* 0 36 0.53125 32WCM183_Z4_1 Tissue 1 86909572 C T CLCA2 p.Q531* 0 106 0.411765 51WCM183_Z4_1 Tissue 19 16006322 C T CYP4F2 p.A113T 0 78 0.142857 63WCM183_Z4_1 Tissue 19 17379781 G A BABAM1 p.A56T 0 115 0.146789 109WCM183_Z4_1 Tissue 19 36051436 C A ATP4A p.G206C 0 129 0.214286 126WCM183_Z4_1 Tissue 19 36351555 C T KIRREL2 p.A305V 0 131 0.206667 150WCM183_Z4_1 Tissue 19 48806005 G A CCDC114 p.R359C 0 156 0.235714 140WCM183_Z4_1 Tissue 19 52658531 C A ZNF836 p.G802V 0 71 0.372093 43WCM183_Z4_1 Tissue 19 55696926 C G PTPRH p.M1002I 0 318 0.257812 256WCM183_Z4_1 Tissue 19 7509218 G C ARHGEF18 p.D309H 0 31 0.25 32WCM183_Z4_1 Tissue 19 9019996 A G MUC16 p.L12500P 0 116 0.207921 101WCM183_Z4_1 Tissue 19 9068625 C T MUC16 p.R6274H 0 209 0.242236 161WCM183_Z4_1 Tissue 20 168682 C G DEFB128 p.E43Q 0 43 0.166667 36WCM183_Z4_1 Tissue 20 2297755 G C TGM3 p.W237C 0 69 0.130435 69WCM183_Z4_1 Tissue 20 35207220 C G TGIF2 p.L15V 0 58 0.489583 96WCM183_Z4_1 Tissue 20 3683989 G T SIGLEC1 p.Y361* 0 213 0.393782 193WCM183_Z4_1 Tissue 20 37182550 A G RALGAPB p.Q1068R 0 80 0.179487 78WCM183_Z4_1 Tissue 20 42223432 C A IFT52 p.L32I 0 140 0.094488 127WCM183_Z4_1 Tissue 20 43090836 C A C20orf62 p.V68F 0 58 0.22449 49WCM183_Z4_1 Tissue 20 4680111 G T PRNP p.G82V 0 68 0.070175 57WCM183_Z4_1 Tissue 20 61288042 C T SLCO4A1 p.S79L 0 59 0.235294 68WCM183_Z4_1 Tissue 2 160621143 A C 7-Mar p.N672H 0 74 0.215686 51WCM183_Z4_1 Tissue 2 1795677 C T MYT1L p.E1175K 0 77 0.155556 45WCM183_Z4_1 Tissue 2 1795679 A G MYT1L p.L1174P 0 77 0.155556 45WCM183_Z4_1 Tissue 2 190557142 C G ANKAR p.Q401E 0 120 0.320988 81WCM183_Z4_1 Tissue 2 197171902 C A HECW2 p.A881S 0 53 0.2 60 WCM183_Z4_1Tissue 2 206036971 G C PARD3B p.V553L 0 67 0.181818 66 WCM183_Z4_1Tissue 2 207615712 G T MDH1B p.A333D 0 89 0.491071 112 WCM183_Z4_1Tissue 22 26348303 C T MYO18B p.R1963* 0 179 0.254658 161 WCM183_Z4_1Tissue 22 26688483 C T SEZ6L p.A69V 0 47 0.183673 49 WCM183_Z4_1 Tissue22 46792553 C T CELSR1 p.G1931D 0 105 0.306667 75 WCM183_Z4_1 Tissue 232693143 C T BIRC6 p.A1915V 0 65 0.236842 76 WCM183_Z4_1 Tissue 271744167 C T DYSF p.R302W 0 210 0.554054 222 WCM183_Z4_1 Tissue 3121415555 A G GOLGB1 p.L1267S 0 45 0.25 36 WCM183_Z4_1 Tissue 3 93603590G C PROS1 p.Q492E 0 70 0.258621 58 WCM183_Z4_1 Tissue 4 134073075 G TPCDH10 p.A594S 0 31 0.648649 37 WCM183_Z4_1 Tissue 4 40824024 G C APBB2p.S658C 0 71 0.36 50 WCM183_Z4_1 Tissue 4 53525295 G T USP46 p.S8Y 0 1170.183099 142 WCM183_Z4_1 Tissue 4 71099764 G T FDCSP p.G40W 0 660.445946 74 WCM183_Z4_1 Tissue 4 74283848 C T ALB p.T341M 0 101 0.41836798 WCM183_Z4_1 Tissue 5 1293872 G A TERT p.R377C 0 72 0.111111 36WCM183_Z4_1 Tissue 5 137727446 G A KDM3B p.A709T 0 144 0.463415 123WCM183_Z4_1 Tissue 5 159996528 T A ATP10B p.T1305S 0 188 0.232068 237WCM183_Z4_1 Tissue 5 34808752 A T RAI14 p.K148I 0 228 0.257353 272WCM183_Z4_1 Tissue 5 35910017 A G CAPSL p.F159S 0 35 0.176471 34WCM183_Z4_1 Tissue 5 76342409 G T AGGF1 p.E370* 0 138 0.554622 119WCM183_Z4_1 Tissue 5 79837548 T C FAM151B p.L243P 0 85 0.35 40WCM183_Z4_1 Tissue 6 121655438 C T TBC1D32 p.D47N 0 137 0.181818 143WCM183_Z4_1 Tissue 6 129634205 G C LAMA2 p.C1125S 0 255 0.190476 252WCM183_Z4_1 Tissue 6 46518129 G A CYP39A1 p.R462* 0 86 0.124031 129WCM183_Z4_1 Tissue 7 100636331 C G MUC12 p.S972R 0 128 0.167883 137WCM183_Z4_1 Tissue 7 100678290 G C MUC17 p.S1198T 0 171 0.260606 165WCM183_Z4_1 Tissue 7 107718670 G T LAMB4 p.S660Y 0 124 0.373832 107WCM183_Z4_1 Tissue 7 117235010 C A CFTR p.S839R 0 151 0.234043 94WCM183_Z4_1 Tissue 7 142961754 G A GSTK1 p.V90M 0 147 0.314286 105WCM183_Z4_1 Tissue 7 150553798 C G AOC1 p.Y80* 0 183 0.276923 130WCM183_Z4_1 Tissue 7 50680445 A T GRB10 p.L396H 0 192 0.124498 249WCM183_Z4_1 Tissue 7 88966340 G C ZNF804B p.L1348F 0 37 0.179104 67WCM183_Z4_1 Tissue 8 118541004 A G MED30 p.K98E 0 48 0.116883 154WCM183_Z4_1 Tissue 8 2857600 C A CSMD1 p.G2696C 0 133 0.609756 123WCM183_Z4_1 Tissue 9 109689821 A T ZNF462 p.I1210F 0 144 0.187879 165WCM183_Z4_1 Tissue 9 116930056 T G COL27A1 p.F74C 0 236 0.090361 166WCM183_Z4_1 Tissue 9 124929180 G A MORN5 p.G61R 0 51 0.440678 59WCM183_Z4_1 Tissue 9 135277689 T G TTF1 p.K174Q 0 43 0.659091 44WCM183_Z4_1 Tissue 9 6007411 C A KIAA2026 p.G126V 0 55 0.09375 32WCM183_Z4_1 Tissue X 26212711 G A MAGEB6 p.V250I 0 98 0.923077 39WCM183_Z4_1 Tissue 1 103412502 C G COL11A1 p.G1060A 0 33 0.060403 149WCM185 Plasma 1 103412502 C G COL11A1 p.G1060A 0 33 0.1 100 WCM185-TP1Plasma 15 53049924 C T ONECUT1 p.R409H 0 32 0.211538 52 WCM185-TP1Plasma 2 96557455 T A ANKRD36C p.N939Y 0 44 0.078947 152 WCM185-TP1Plasma 8 91837017 A G NECAB1 p.H66R 0 36 0.2 100 WCM185-TP1 Plasma 1103412502 C G COL11A1 p.G1060A 0 33 0.368852 122 WCM185-TP2 Plasma 112819361 G T C1orf158 p.R115L 0 34 0.086957 46 WCM185-TP2 Plasma 1185418516 C T SYTL2 p.V687I 0 39 0.256637 113 WCM185-TP2 Plasma 1553049924 C T ONECUT1 p.R409H 0 32 0.254545 55 WCM185-TP2 Plasma 296557455 T A ANKRD36C p.N939Y 0 44 0.063694 157 WCM185-TP2 Plasma 891837017 A G NECAB1 p.H66R 0 36 0.267857 112 WCM185-TP2 Plasma 1103412502 C G COL11A1 p.G1060A 0 33 0.401869 107 WCM185-TP3 Plasma 1185418516 C T SYTL2 p.V687I 0 39 0.230769 117 WCM185-TP3 Plasma 1553049924 C T ONECUT1 p.R409H 0 32 0.326923 52 WCM185-TP3 Plasma 296557455 T A ANKRD36C p.N939Y 0 44 0.070423 142 WCM185-TP3 Plasma 891837017 A G NECAB1 p.H66R 0 36 0.301075 93 WCM185-TP3 Plasma 1553049924 C T ONECUT1 p.R409H 0 32 0.104478 67 WCM185-TP4 Plasma 296557455 T A ANKRD36C p.N939Y 0 44 0.077922 154 WCM185-TP4 Plasma 4169189013 G T DDX60 p.Q970K 0 34 0.052632 76 WCM185-TP4 Plasma 10108371773 G A SORCS1 p.R977W 0 99 0.084507 71 WCM185_X1_1 Tissue 1087966267 C A GRID1 p.R125L 0 31 0.081081 37 WCM185_X1_1 Tissue 1131327201 T C DCDC1 p.T239A 0 151 0.081967 122 WCM185_X1_1 Tissue 1156914912 C T ARHGEF11 p.V924I 0 37 0.151515 33 WCM185_X1_1 Tissue 1164335269 C A SLC22A11 p.N419K 0 103 0.098361 61 WCM185_X1_1 Tissue 1205129365 C A DSTYK p.G661V 0 82 0.076923 78 WCM185_X1_1 Tissue 12130648167 C A FZD10 p.A227E 0 74 0.096774 62 WCM185_X1_1 Tissue 1553049924 C T ONECUT1 p.R409H 0 75 0.129032 31 WCM185_X1_1 Tissue 1675688215 G T TERF2IP p.V239L 0 51 0.068182 44 WCM185_X1_1 Tissue 1711572819 C T DNAH9 p.R1021W 0 121 0.065217 46 WCM185_X1_1 Tissue 1747696643 A C SPOP p.F102C 0 96 0.072727 110 WCM185_X1_1 Tissue 1952919239 G T ZNF528 p.R378S 0 68 0.130435 46 WCM185_X1_1 Tissue 2172928495 C A METAP1D p.S85R 0 77 0.065217 46 WCM185_X1_1 Tissue 2176958096 G A HOXD13 p.G160R 0 88 0.072165 97 WCM185_X1_1 Tissue 271650878 G T ZNF638 p.E1412* 0 56 0.088889 45 WCM185_X1_1 Tissue 48442605 G T TRMT44 p.G19V 0 109 0.057971 138 WCM185_X1_1 Tissue 5113698689 C A KCNN2 p.H73N 0 62 0.086957 69 WCM185_X1_1 Tissue 624718813 G T C6orf62 p.D28E 0 80 0.06383 47 WCM185_X1_1 Tissue 7102079481 C A ORAI2 p.Y26* 0 52 0.096774 31 WCM185_X1_1 Tissue 9139889462 C T CLIC3 p.E158K 0 71 0.125 32 WCM185_X1_1 Tissue X 12903734G T TLR7 p.C36F 0 121 0.125 48 WCM185_X1_1 Tissue 10 25887500 A G GPR158p.N982S 0 232 0.403433 233 WCM185_Z1_1 Tissue 1 103412502 C G COL11A1p.G1060A 0 85 0.368794 141 WCM185_Z1_1 Tissue 1 208207879 G T PLXNA2p.P1608H 0 41 0.061224 49 WCM185_Z1_1 Tissue 15 32460211 G A CHRNA7p.R354H 0 35 0.354839 31 WCM185_Z1_1 Tissue 15 53049924 C T ONECUT1p.R409H 0 75 0.397959 98 WCM185_Z1_1 Tissue 15 70345681 C G TLE3 p.C623S0 88 0.39 100 WCM185_Z1_1 Tissue 17 47696643 A C SPOP p.F102C 0 96 0.408125 WCM185_Z1_1 Tissue 22 32012774 C T SFI1 p.P1115L 0 121 0.386364 176WCM185_Z1_1 Tissue 2 71650878 G T ZNF638 p.E1412* 0 56 0.344262 61WCM185_Z1_1 Tissue 5 82833515 G A VCAN p.A1565T 0 106 0.318966 116WCM185_Z1_1 Tissue 6 53519871 C T KLHL31 p.R67Q 0 206 0.294964 278WCM185_Z1_1 Tissue 8 67926691 T G PPP1R42 p.N89T 0 37 0.21875 32WCM185_Z1_1 Tissue 8 91837017 A G NECAB1 p.H66R 0 87 0.344828 58WCM185_Z1_1 Tissue 15 72645482 C T HEXA p.R166H 0 44 0.097561 82 WCM192Plasma 20 9624840 G A PAK7 p.T46M 0 34 0.051948 77 WCM192 Plasma 2190660510 G A PMS1 p.D50N 0 41 0.084337 83 WCM192 Plasma 6 20212428 C TMBOAT1 p.R13H 0 37 0.053333 75 WCM192 Plasma 9 94172733 C T NFIL3 p.R95Q0 42 0.136364 66 WCM192 Plasma 10 100190955 G A HPS1 p.R201W 0 860.169492 59 WCM192_X1_1 Tissue 10 128193341 G A C10orf90 p.T143M 0 1160.054545 110 WCM192_X1_1 Tissue 10 22498209 A G EBLN1 p.M235T 0 1050.102564 39 WCM192_X1_1 Tissue 10 22498468 C T EBLN1 p.G149R 0 870.065217 92 WCM192_X1_1 Tissue 10 97444321 C T TCTN3 p.G344R 0 920.109589 73 WCM192_X1_1 Tissue 10 97453433 G A TCTN3 p.A75V 0 520.093023 43 WCM192_X1_1 Tissue 11 1080487 G A MUC2 p.A377T 0 1220.068063 191 WCM192_X1_1 Tissue 11 129245968 G T BARX2 p.G13V 0 620.358209 67 WCM192_X1_1 Tissue 1 119927488 C G HAO2 p.R125G 0 1180.294118 34 WCM192_X1_1 Tissue 1 1361641 C T TMEM88B p.P45L 0 320.173077 52 WCM192_X1_1 Tissue 11 4608076 C T OR52I2 p.L12F 0 35 0.17540 WCM192_X1_1 Tissue 1 1500277 G A SSU72 p.R34* 0 54 0.516129 31WCM192_X1_1 Tissue 1 151140732 G A SCNM1 p.E171K 0 149 0.105263 152WCM192_X1_1 Tissue 1 156567904 G A GPATCH4 p.Q91* 0 142 0.387097 93WCM192_X1_1 Tissue 1 161145823 A G B4GALT3 p.C10R 0 154 0.066667 225WCM192_X1_1 Tissue 11 8662516 T C TRIM66 p.H324R 0 64 0.1 40 WCM192_X1_1Tissue 11 9087449 C T SCUBE2 p.R280Q 0 74 0.088235 34 WCM192_X1_1 Tissue1 201176651 C T IGFN1 p.T877M 0 252 0.053628 317 WCM192_X1_1 Tissue 1201181994 A G IGFN1 p.D2658G 0 364 0.077406 478 WCM192_X1_1 Tissue 1202097559 G A GPR37L1 p.G441R 0 64 0.115385 52 WCM192_X1_1 Tissue 120417135 C G PLA2G5 p.R123G 0 173 0.067633 207 WCM192_X1_1 Tissue 1211956765 C T LPGAT1 p.W178* 0 59 0.068493 73 WCM192_X1_1 Tissue 1222487045 C T ST8SIA1 p.C41Y 0 203 0.089286 112 WCM192_X1_1 Tissue 123280424 G T LACTBL1 p.N251K 0 50 0.244444 45 WCM192_X1_1 Tissue 1232941142 G A MAP10 p.G125S 0 120 0.057471 87 WCM192_X1_1 Tissue 124718079 C A STPG1 p.S54I 0 81 0.06 150 WCM192_X1_1 Tissue 12 49918501 GA SPATS2 p.R383Q 0 70 0.119048 42 WCM192_X1_1 Tissue 12 50727811 C TFAM186A p.M2193I 0 84 0.133333 45 WCM192_X1_1 Tissue 12 70351684 C AMYRFL p.L845M 0 41 0.118644 59 WCM192_X1_1 Tissue 12 8043659 C T SLC2A14p.R22Q 0 50 0.117647 34 WCM192_X1_1 Tissue 13 32910749 T A BRCA2 p.F753I0 56 0.4 50 WCM192_X1_1 Tissue 14 20404046 C G OR4K1 p.S74C 0 630.096774 62 WCM192_X1_1 Tissue 14 21542698 C T ARHGEF40 p.T270M 0 780.10989 91 WCM192_X1_1 Tissue 14 24771514 A G NOP9 p.R343G 0 57 0.1 50WCM192_X1_1 Tissue 1 47139103 C T TEX38 p.A199V 0 174 0.072289 166WCM192_X1_1 Tissue 1 48241061 G A TRABD2B p.P377L 0 32 0.131579 38WCM192_X1_1 Tissue 1 49511311 C T AGBL4 p.S180N 0 58 0.088235 34WCM192_X1_1 Tissue 14 99983489 G A CCDC85C p.S336L 0 245 0.056338 213WCM192_X1_1 Tissue 15 45658378 G A GATM p.R282C 0 37 0.354839 31WCM192_X1_1 Tissue 15 79750690 G A KIAA1024 p.R734H 0 130 0.051546 97WCM192_X1_1 Tissue 1 5934559 A C NPHP4 p.F1068C 0 92 0.0625 48WCM192_X1_1 Tissue 15 93749883 G A AC112693.2 p.R154Q 0 338 0.060086 233WCM192_X1_1 Tissue 16 4625274 A G C16orf96 p.I265V 0 176 0.069959 243WCM192_X1_1 Tissue 16 46771923 T C MYLK3 p.Q234R 0 39 0.1875 32WCM192_X1_1 Tissue 16 58079165 G A MMP15 p.G609R 0 133 0.213333 75WCM192_X1_1 Tissue 16 66792714 T C CCDC79 p.Q653R 0 90 0.080645 124WCM192_X1_1 Tissue 16 75728368 A G AC025287.1 p.M150T 0 162 0.078947 114WCM192_X1_1 Tissue 16 77246517 C A SYCE1L p.P210T 0 42 0.142857 42WCM192_X1_1 Tissue 16 824442 C T MSLNL p.S249N 0 112 0.394366 142WCM192_X1_1 Tissue 16 84497316 A C ATP2C2 p.Q940P 0 110 0.065934 91WCM192_X1_1 Tissue 16 88501971 T A ZNF469 p.L2670Q 0 139 0.119718 142WCM192_X1_1 Tissue 16 88803124 T C PIEZO1 p.R407G 0 66 0.1875 48WCM192_X1_1 Tissue 17 11881792 G T ZNF18 p.H378N 0 38 0.081633 49WCM192_X1_1 Tissue 17 17250197 G A NT5M p.R208H 0 77 0.090909 66WCM192_X1_1 Tissue 17 19861701 C T AKAP10 p.R168Q 0 81 0.394737 76WCM192_X1_1 Tissue 17 33805180 G C SLFN12L p.A373G 0 157 0.086614 127WCM192_X1_1 Tissue 17 37319065 C T ARL5C p.V52M 0 149 0.19917 241WCM192_X1_1 Tissue 17 37319103 T C ARL5C p.N39S 0 81 0.195804 143WCM192_X1_1 Tissue 17 39186168 A C KRTAP1-4 p.S55A 0 35 0.050847 59WCM192_X1_1 Tissue 17 42981499 C T FAM187A p.T101I 0 115 0.07362 163WCM192_X1_1 Tissue 17 42982288 A G FAM187A p.H364R 0 50 0.105263 38WCM192_X1_1 Tissue 17 71452153 A G SDK2 p.V124A 0 104 0.097222 72WCM192_X1_1 Tissue 17 72368641 G A GPR142 p.D431N 0 128 0.057325 157WCM192_X1_1 Tissue 17 73602081 G A MYO15B p.R207H 0 83 0.060606 99WCM192_X1_1 Tissue 17 7577515 T G TP53 p.T256P 0 114 0.447368 152WCM192_X1_1 Tissue 17 76490147 C T DNAH17 p.V2122I 0 68 0.08547 117WCM192_X1_1 Tissue 18 21484014 G A LAMA3 p.A2146T 0 111 0.057377 122WCM192_X1_1 Tissue 18 28659828 G A DSC2 p.L550F 0 64 0.121212 66WCM192_X1_1 Tissue 18 51813694 A G POLI p.I371V 0 73 0.065574 61WCM192_X1_1 Tissue 18 71740791 C G FBXO15 p.V480L 0 81 0.075758 66WCM192_X1_1 Tissue 18 72021145 T A C18orf63 p.F548Y 0 131 0.051813 193WCM192_X1_1 Tissue 19 1533972 C G PLK5 p.L253V 0 90 0.097222 72WCM192_X1_1 Tissue 19 1535205 G C PLK5 p.G323R 0 125 0.053191 94WCM192_X1_1 Tissue 19 16860493 A T NWD1 p.K347M 0 179 0.064885 262WCM192_X1_1 Tissue 1 91840949 C A HFM1 p.A551S 0 60 0.085714 35WCM192_X1_1 Tissue 19 18780018 C T KLHL26 p.A604V 0 54 0.073684 95WCM192_X1_1 Tissue 19 37488299 A G ZNF568 p.E505G 0 136 0.08 150WCM192_X1_1 Tissue 19 37488472 C G ZNF568 p.P563A 0 101 0.053191 94WCM192_X1_1 Tissue 19 37488481 G C ZNF568 p.G566R 0 102 0.052632 95WCM192_X1_1 Tissue 19 38160916 C T ZNF781 p.R45H 0 34 0.512821 39WCM192_X1_1 Tissue 19 38377773 G A WDR87 p.R2141W 0 95 0.061069 131WCM192_X1_1 Tissue 19 38997475 G A RYR1 p.G2900E 0 195 0.114478 297WCM192_X1_1 Tissue 19 6040238 G T RFX2 p.T92N 0 83 0.126316 95WCM192_X1_1 Tissue 20 18296291 G A ZNF133 p.G266R 0 69 0.066667 60WCM192_X1_1 Tissue 20 31196431 T C RP11- p.L117P 0 94 0.055556 108WCM192_X1_1 Tissue 410N8.4 20 33345053 C T NCOA6 p.G500R 0 107 0.07594979 WCM192_X1_1 Tissue 2 163124030 C T IFIH1 p.D953N 0 45 0.146341 41WCM192_X1_1 Tissue 2 179914640 G A CCDC141 p.A10V 0 221 0.070352 199WCM192_X1_1 Tissue 2 190660510 G A PMS1 p.D50N 0 50 0.348485 66WCM192_X1_1 Tissue 22 18835298 T C AC008132.13 p.V285A 0 50 0.050633 79WCM192_X1_1 Tissue 2 228566904 T G SLC19A3 p.K44T 0 56 0.105263 38WCM192_X1_1 Tissue 22 31521404 G A INPP5J p.A227T 0 104 0.100559 179WCM192_X1_1 Tissue 2 239133980 C T AC016757.3 p.G99R 0 72 0.290323 62WCM192_X1_1 Tissue 22 41631282 T C CHADL p.Q710R 0 196 0.055249 181WCM192_X1_1 Tissue 2 27930837 C T AC074091.13 p.G66R 0 150 0.19469 113WCM192_X1_1 Tissue 2 54197829 C A PSME4 p.E31D 0 54 0.076923 91WCM192_X1_1 Tissue 2 69046366 A T ARHGAP25 p.K371M 0 203 0.074324 148WCM192_X1_1 Tissue 2 97633267 G C FAM178B p.P390A 0 48 0.069444 72WCM192_X1_1 Tissue 3 113010544 C T WDR52 p.V1809I 0 109 0.088889 90WCM192_X1_1 Tissue 3 113045325 G A WDR52 p.R1495W 0 142 0.123077 65WCM192_X1_1 Tissue 3 113049270 T A WDR52 p.K1287N 0 79 0.206897 87WCM192_X1_1 Tissue 3 126071216 G C KLF15 p.P184A 0 159 0.073394 109WCM192_X1_1 Tissue 3 130113771 G A COL6A5 p.D1011N 0 80 0.083333 96WCM192_X1_1 Tissue 3 138739355 C T PRR23B p.G50E 0 55 0.117647 85WCM192_X1_1 Tissue 3 142840685 C T CHST2 p.R343C 0 38 0.5 74 WCM192_X1_1Tissue 3 196311106 G T FBXO45 p.V260F 0 100 0.326923 52 WCM192_X1_1Tissue 3 20042834 C T PP2D1 p.A260T 0 123 0.065217 46 WCM192_X1_1 Tissue3 42700517 G C ZBTB47 p.G224R 0 151 0.112782 133 WCM192_X1_1 Tissue 342700518 G T ZBTB47 p.G224V 0 151 0.112782 133 WCM192_X1_1 Tissue 353126396 C A RFT1 p.A483S 0 94 0.069652 201 WCM192_X1_1 Tissue 356716922 T G FAM208A p.Q38P 0 60 0.114286 70 WCM192_X1_1 Tissue 39896259 T A TTLL3 p.M312K 0 74 0.080645 62 WCM192_X1_1 Tissue 4114277956 G A ANK2 p.E2728K 0 57 0.857143 35 WCM192_X1_1 Tissue 4122681487 T C TMEM155 p.T119A 0 192 0.082707 133 WCM192_X1_1 Tissue 413606303 C A BOD1L1 p.V741L 0 99 0.050955 157 WCM192_X1_1 Tissue 4146567227 G A MMAA p.G218R 0 95 0.092105 76 WCM192_X1_1 Tissue 4155410650 T C DCHS2 p.T620A 0 83 0.138889 72 WCM192_X1_1 Tissue 4155410667 G A DCHS2 p.A614V 0 82 0.140845 71 WCM192_X1_1 Tissue 424801834 C G SOD3 p.R231G 0 60 0.189189 74 WCM192_X1_1 Tissue 4 25915957G A SMIM20 p.A8T 0 70 0.078652 89 WCM192_X1_1 Tissue 4 36310065 G ADTHD1 p.R557Q 0 92 0.055556 126 WCM192_X1_1 Tissue 4 52938246 G ASPATA18 p.D228N 0 311 0.411594 345 WCM192_X1_1 Tissue 4 74019788 T AANKRD17 p.D348V 0 84 0.067416 89 WCM192_X1_1 Tissue 5 134724624 C TH2AFY p.E54K 0 112 0.142373 295 WCM192_X1_1 Tissue 5 137765595 G A KDM3Bp.A1612T 0 140 0.604651 172 WCM192_X1_1 Tissue 5 149406271 C T HMGXB3p.A488V 0 123 0.10084 119 WCM192_X1_1 Tissue 5 151775064 C G NMUR2p.S298T 0 180 0.13308 263 WCM192_X1_1 Tissue 5 167645814 C T TENM2p.R1640W 0 120 0.094737 95 WCM192_X1_1 Tissue 5 180278091 T C ZFP62p.N135S 0 117 0.057971 69 WCM192_X1_1 Tissue 5 6746450 G A PAPD7 p.G207S0 113 0.414062 128 WCM192_X1_1 Tissue 5 93987532 C A ANKRD32 p.S288R 081 0.196078 51 WCM192_X1_1 Tissue 6 101215163 A G ASCC3 p.F485S 0 1080.058824 85 WCM192_X1_1 Tissue 6 131148737 G A SMLR1 p.V62M 0 560.059701 67 WCM192_X1_1 Tissue 6 18171684 G A KDM1B p.G170S 0 560.073171 41 WCM192_X1_1 Tissue 6 30995532 T C MUC22 p.M775T 0 570.066667 45 WCM192_X1_1 Tissue 6 31526225 G A NFKBIL1 p.G328E 0 570.157143 70 WCM192_X1_1 Tissue 6 49485266 C A GLYATL3 p.Q104K 0 1420.057554 139 WCM192_X1_1 Tissue 6 656256 C T HUS1B p.R230Q 0 1190.064935 77 WCM192_X1_1 Tissue 6 73843172 C T KCNQ5 p.R426C 0 490.516129 31 WCM192_X1_1 Tissue 7 102098253 A C ALKBH4 p.I166S 0 570.055556 54 WCM192_X1_1 Tissue 7 12376811 A C VWDE p.F1485C 0 1160.105263 38 WCM192_X1_1 Tissue 7 12428803 G A VWDE p.S142F 0 1880.106061 132 WCM192_X1_1 Tissue 7 127999645 C T PRRT4 p.R134Q 0 820.077922 154 WCM192_X1_1 Tissue 7 141759668 T A MGAM p.S1321T 0 1020.083333 120 WCM192_X1_1 Tissue 7 141759669 C G MGAM p.S1321C 0 1020.083333 120 WCM192_X1_1 Tissue 7 46729069 A G AC011294.3 p.C83R 0 890.121212 66 WCM192_X1_1 Tissue 8 12957852 C T DLC1 p.R665H 0 1320.051095 137 WCM192_X1_1 Tissue 8 61768636 C T CHD7 p.P2347S 0 1420.053398 206 WCM192_X1_1 Tissue 9 271638 C T DOCK8 p.A22V 0 144 0.111111108 WCM192_X1_1 Tissue 9 33572347 T C ANKRD18B p.F1009L 0 66 0.140625 64WCM192_X1_1 Tissue 9 94172733 C T NFIL3 p.R95Q 0 130 0.306533 199WCM192_X1_1 Tissue X 27766045 A G DCAF8L2 p.T345A 0 96 0.081818 110WCM192_X1_1 Tissue 11 129245968 G T BARX2 p.G13V 0 62 0.135802 81WCM192_Z1_1 Tissue 11 134856546 A T AP003062.1 p.N385I 0 137 0.240741108 WCM192_Z1_1 Tissue 1 22816907 G T ZBTB40 p.E156* 0 46 0.14 50WCM192_Z1_1 Tissue 13 32910749 T A BRCA2 p.F753I 0 56 0.3125 48WCM192_Z1_1 Tissue 13 58298857 G A PCDH17 p.R970H 0 52 0.071429 42WCM192_Z1_1 Tissue 14 75989058 C G BATF p.S11R 0 39 0.095238 42WCM192_Z1_1 Tissue 16 11272248 G T CLEC16A p.V955F 0 79 0.116505 103WCM192_Z1_1 Tissue 16 824442 C T MSLNL p.S249N 0 112 0.185185 81WCM192_Z1_1 Tissue 17 19861701 C T AKAP10 p.R168Q 0 81 0.272727 88WCM192_Z1_1 Tissue 17 7577515 T G TP53 p.T256P 0 114 0.268116 138WCM192_Z1_1 Tissue 1 91404282 C T ZNF644 p.E877K 0 60 0.111111 72WCM192_Z1_1 Tissue 19 38160916 C T ZNF781 p.R45H 0 34 0.407407 54WCM192_Z1_1 Tissue 2 190660510 G A PMS1 p.D50N 0 50 0.297297 37WCM192_Z1_1 Tissue 3 142840685 C T CHST2 p.R343C 0 38 0.54717 53WCM192_Z1_1 Tissue 3 196311106 G T FBXO45 p.V260F 0 100 0.180851 94WCM192_Z1_1 Tissue 4 114277956 G A ANK2 p.E2728K 0 57 0.4 45 WCM192_Z1_1Tissue 4 52938246 G A SPATA18 p.D228N 0 311 0.084444 225 WCM192_Z1_1Tissue 5 137765595 G A KDM3B p.A1612T 0 140 0.294643 112 WCM192_Z1_1Tissue 6 73843172 C T KCNQ5 p.R426C 0 49 0.25 52 WCM192_Z1_1 Tissue 8133083719 T C HHLA1 p.K446R 0 103 0.068376 117 WCM192_Z1_1 Tissue 994172733 C T NFIL3 p.R95Q 0 130 0.27027 148 WCM192_Z1_1 Tissue 12105550563 G T KIAA1033 p.A940S 0 34 0.059701 67 WCM195 Plasma 4151408923 C T LRBA p.R2182H 0 62 0.052632 95 WCM195 Plasma 10 60124595 TC UBE2D1 p.I88T 0 158 0.985714 70 WCM195_Z8_1 Tissue 11 67800419 G ANDUFS8 p.D47N 0 113 0.724409 127 WCM195_Z8_1 Tissue 11 75141328 C TKLHL35 p.R116Q 0 78 0.688889 45 WCM195_Z8_1 Tissue 1 185959521 C T HMCN1p.P1108L 0 214 0.210784 204 WCM195_Z8_1 Tissue 12 6230355 A G VWF p.S69P0 238 0.263636 220 WCM195_Z8_1 Tissue 1 29630427 G A PTPRU p.R856H 0 920.287879 66 WCM195_Z8_1 Tissue 13 92345711 G A GPC5 p.R199Q 0 1620.054645 183 WCM195_Z8_1 Tissue 1 43895513 C T SZT2 p.Q1379* 0 1420.606299 127 WCM195_Z8_1 Tissue 14 94173103 C A UNC79 p.N2587K 0 1030.268817 93 WCM195_Z8_1 Tissue 16 70599128 A G SF3B3 p.N875S 0 147 0.352125 WCM195_Z8_1 Tissue 17 38346743 G A RAPGEFL1 p.S240N 0 233 0.212698315 WCM195_Z8_1 Tissue 17 40695867 C T NAGLU p.R615C 0 70 0.070588 85WCM195_Z8_1 Tissue 1 75078464 G A C1orf173 p.H344Y 0 132 0.168224 214WCM195_Z8_1 Tissue 17 78013859 C A CCDC40 p.Y114* 0 202 0.063158 190WCM195_Z8_1 Tissue 1 7812577 C T CAMTA1 p.R1648C 0 77 0.646341 82WCM195_Z8_1 Tissue 18 29039945 C T DSG3 p.R219C 0 91 0.528736 87WCM195_Z8_1 Tissue 18 33706813 C G SLC39A6 p.R53P 0 175 0.444444 135WCM195_Z8_1 Tissue 19 10080580 C T COL5A3 p.G1319S 0 192 0.108844 147WCM195_Z8_1 Tissue 19 57931006 G T ZNF17 p.C49F 0 54 0.071429 70WCM195_Z8_1 Tissue 20 17437080 G A PCSK2 p.A397T 0 52 0.454545 44WCM195_Z8_1 Tissue 20 17437081 C T PCSK2 p.A397V 0 52 0.454545 44WCM195_Z8_1 Tissue 2 20454691 C T PUM2 p.D937N 0 74 0.3875 80WCM195_Z8_1 Tissue 2 234197 C T SH3YL1 p.G123R 0 276 0.521951 205WCM195_Z8_1 Tissue 22 38042916 C G SH3BP1 p.S339C 0 80 0.677966 59WCM195_Z8_1 Tissue 3 113377900 G T KIAA2018 p.P877T 0 104 0.418182 110WCM195_Z8_1 Tissue 3 38081110 G A DLEC1 p.V132M 0 73 0.235849 106WCM195_Z8_1 Tissue 4 151408923 C T LRBA p.R2182H 0 200 0.583333 168WCM195_Z8_1 Tissue 4 154709944 G A SFRP2 p.S15L 0 341 0.304833 269WCM195_Z8_1 Tissue 4 47578826 T G ATP10D p.C1135G 0 67 0.454545 77WCM195_Z8_1 Tissue 5 140734993 G A PCDHGA4 p.A76T 0 190 0.506494 231WCM195_Z8_1 Tissue 5 150029332 T A SYNPO p.S743T 0 212 0.45 160WCM195_Z8_1 Tissue 5 43533872 G T PAIP1 p.S407Y 0 90 0.206349 126WCM195_Z8_1 Tissue 6 75848587 G A COL12A1 p.S1683F 0 139 0.069565 115WCM195_Z8_1 Tissue 6 93956516 C A EPHA7 p.C907F 0 120 0.330189 106WCM195_Z8_1 Tissue 7 151049965 C G NUB1 p.L138V 0 71 0.542857 70WCM195_Z8_1 Tissue 9 136260749 G A C9orf96 p.R242Q 0 79 0.354839 124WCM195_Z8_1 Tissue 10 8056602 C A TAF3 p.P893H 0 65 0.197531 81 WCM198Plasma 1 103544263 C A COL11A1 p.A147S 0 92 0.102564 78 WCM198 Plasma 11117985555 C A TMPRSS4 p.P308T 0 41 0.210526 38 WCM198 Plasma 11124189793 G T OR8D2 p.L101I 0 63 0.210526 57 WCM198 Plasma 11 128839629G A ARHGAP32 p.R1813C 0 46 0.365385 52 WCM198 Plasma 11 35211528 T GCD44 p.F195V 0 50 0.283582 67 WCM198 Plasma 1 165218668 A G LMX1Ap.V158A 0 37 0.302326 43 WCM198 Plasma 11 984696 C G AP2A2 p.P253A 0 450.28 50 WCM198 Plasma 1 21191626 G C EIF4G3 p.L862V 0 67 0.109589 73WCM198 Plasma 1 223983975 G T TP53BP2 p.Q756K 0 59 0.054795 73 WCM198Plasma 1 231124091 A G ARV1 p.K67R 0 62 0.2625 80 WCM198 Plasma 1253165684 G A KRT76 p.R412W 0 74 0.255814 86 WCM198 Plasma 12 54396308 TA HOXC9 p.F211L 0 64 0.188406 69 WCM198 Plasma 12 57038648 A C ATP5Bp.I134M 0 68 0.352941 68 WCM198 Plasma 1 43166462 C T YBX1 p.R251C 0 670.15873 63 WCM198 Plasma 16 21982885 T G UQCRC2 p.F237C 0 84 0.230769 78WCM198 Plasma 16 21982886 T A UQCRC2 p.F237L 0 84 0.226667 75 WCM198Plasma 17 35946569 T C SYNRG p.Q110R 0 71 0.212121 66 WCM198 Plasma 1741861224 G T C17orf105 p.R153I 0 67 0.258824 85 WCM198 Plasma 1741861225 A T C17orf105 p.R153S 0 66 0.238095 84 WCM198 Plasma 1749726562 G C CA10 p.I205M 0 60 0.060976 82 WCM198 Plasma 19 58024413 G AZNF773 p.A111T 0 62 0.25 76 WCM198 Plasma 20 33734650 C T EDEM2 p.D66N 045 0.294118 68 WCM198 Plasma 20 61444348 G T OGFR p.V461L 0 46 0.43636455 WCM198 Plasma 2 155157983 G A GALNT13 p.R346Q 0 63 0.22449 49 WCM198Plasma 2 166870330 G A SCN1A p.T1210M 0 59 0.253731 67 WCM198 Plasma 2179592875 G T TTN p.A6242E 0 49 0.076923 39 WCM198 Plasma 3 44763445 A GZNF502 p.Y379C 0 56 0.290323 62 WCM198 Plasma 4 100131657 C T ADH6p.D89N 0 103 0.242718 103 WCM198 Plasma 4 153247289 G A FBXW7 p.R505C 054 0.20339 59 WCM198 Plasma 4 76720821 C T USO1 p.T509I 0 84 0.2625 80WCM198 Plasma 5 140720039 T A PCDHGA2 p.L501I 0 67 0.277778 54 WCM198Plasma 5 157233022 G A CLINT1 p.T265I 0 105 0.383838 99 WCM198 Plasma 523521190 C A PRDM9 p.A137E 0 61 0.15 100 WCM198 Plasma 6 118606422 G CSLC35F1 p.S308T 0 40 0.216667 60 WCM198 Plasma 6 146480672 C T GRM1p.R297* 0 48 0.37931 58 WCM198 Plasma 7 48033962 C A SUN3 p.V271L 0 730.255814 86 WCM198 Plasma 8 68931857 A C PREX2 p.H96P 0 76 0.181818 99WCM198 Plasma 9 101258697 T G GABBR2 p.K244Q 0 41 0.346154 78 WCM198Plasma 10 8056602 C A TAF3 p.P893H 0 135 0.508621 116 WCM198_Z1_1 Tissue11 117985555 C A TMPRSS4 p.P308T 0 79 0.413333 75 WCM198_Z1_1 Tissue 11124189793 G T OR8D2 p.L101I 0 45 0.371429 35 WCM198_Z1_1 Tissue 11128839629 G A ARHGAP32 p.R1813C 0 126 0.509202 163 WCM198_Z1_1 Tissue 1135211528 T G CD44 p.F195V 0 72 0.44898 49 WCM198_Z1_1 Tissue 1 15789913C A CELA2A p.P130H 0 36 0.078947 38 WCM198_Z1_1 Tissue 1 165218668 A GLMX1A p.V158A 0 86 0.487805 82 WCM198_Z1_1 Tissue 1 179520434 C A NPHS2p.L342F 0 112 0.441379 145 WCM198_Z1_1 Tissue 11 984696 C G AP2A2p.P253A 0 73 0.452055 73 WCM198_Z1_1 Tissue 1 2252995 C T MORN1 p.D441N0 54 0.458333 48 WCM198_Z1_1 Tissue 1 231124091 A G ARV1 p.K67R 0 760.578125 64 WCM198_Z1_1 Tissue 12 53165684 G A KRT76 p.R412W 0 2540.469194 211 WCM198_Z1_1 Tissue 12 54396308 T A HOXC9 p.F211L 0 76 0.6650 WCM198_Z1_1 Tissue 12 57038648 A C ATP5B p.I134M 0 207 0.39521 167WCM198_Z1_1 Tissue 1 43166462 C T YBX1 p.R251C 0 74 0.432836 67WCM198_Z1_1 Tissue 15 93545479 C A CHD2 p.Q1404K 0 41 0.066667 45WCM198_Z1_1 Tissue 16 2812022 G T SRRM2 p.R498L 0 50 0.285714 42WCM198_Z1_1 Tissue 17 35946569 T C SYNRG p.Q110R 0 164 0.292929 198WCM198_Z1_1 Tissue 17 39503402 G C KRT33A p.L221V 0 108 0.281818 110WCM198_Z1_1 Tissue 17 7573982 C A TP53 p.E349* 0 98 0.909091 99WCM198_Z1_1 Tissue 19 15575069 G A RASAL3 p.A34V 0 50 0.647059 68WCM198_Z1_1 Tissue 19 58024413 G A ZNF773 p.A111T 0 58 0.409091 66WCM198_Z1_1 Tissue 20 33734650 C T EDEM2 p.D66N 0 180 0.392405 158WCM198_Z1_1 Tissue 20 61444348 G T OGFR p.V461L 0 118 0.634146 164WCM198_Z1_1 Tissue 2 219557366 C T STK36 p.S659F 0 35 0.438596 57WCM198_Z1_1 Tissue 3 44763445 A G ZNF502 p.Y379C 0 60 0.591837 49WCM198_Z1_1 Tissue 4 100131657 C T ADH6 p.D89N 0 96 0.462963 108WCM198_Z1_1 Tissue 4 153247289 G A FBXW7 p.R505C 0 80 0.468354 79WCM198_Z1_1 Tissue 4 76720821 C T USO1 p.T509I 0 133 0.367188 128WCM198_Z1_1 Tissue 5 140720039 T A PCDHGA2 p.L501I 0 91 0.33913 115WCM198_Z1_1 Tissue 5 157233022 G A CLINT1 p.T265I 0 73 0.584416 77WCM198_Z1_1 Tissue 5 23521190 C A PRDM9 p.A137E 0 74 0.188406 138WCM198_Z1_1 Tissue 6 34004374 G A GRM4 p.R505W 0 71 0.275 80 WCM198_Z1_1Tissue 7 48033962 C A SUN3 p.V271L 0 72 0.439394 66 WCM198_Z1_1 Tissue 9139815643 C T TRAF2 p.R372C 0 50 0.1125 80 WCM198_Z1_1 Tissue 11 1093105C G MUC2 p.P1642A 0 31 0.092308 65 WCM199 Plasma 15 43748117 A C TP53BP1p.S892A 0 37 0.055556 72 WCM199 Plasma 8 101276403 A T RNF19A p.L443I 036 0.089286 56 WCM199 Plasma 10 95791303 G C PLCE1 p.G167A 0 102 0.5 68WCM199_Z3_1 Tissue 11 26558959 G A ANO3 p.R328H 0 61 0.288136 59WCM199_Z3_1 Tissue 1 156821872 C G INSRR p.R250P 0 44 0.634146 82WCM199_Z3_1 Tissue 1 44436817 C T DPH2 p.A147V 0 242 0.381503 346WCM199_Z3_1 Tissue 15 40584342 C T PLCB2 p.A817T 0 186 0.4 155WCM199_Z3_1 Tissue 19 33623148 G A WDR88 p.A25T 0 82 0.3125 64WCM199_Z3_1 Tissue 1 94564442 G A ABCA4 p.R226C 0 108 0.053763 93WCM199_Z3_1 Tissue 2 233323651 G A ALPI p.R461H 0 81 0.085106 47WCM199_Z3_1 Tissue 3 185782211 T C ETV5 p.H322R 0 86 0.324176 182WCM199_Z3_1 Tissue 4 46043213 G A GABRG1 p.P397L 0 34 0.5 34 WCM199_Z3_1Tissue 6 44358075 A T CDC5L p.H39L 0 146 0.423077 130 WCM199_Z3_1 Tissue8 24356786 T C ADAM7 p.V627A 0 102 0.210191 157 WCM199_Z3_1 Tissue 827764754 C G SCARA5 p.G336A 0 88 0.062016 129 WCM199_Z3_1 Tissue 92056721 C T SMARCA2 p.T408M 0 127 0.366197 71 WCM199_Z3_1 Tissue 935665136 G A ARHGEF39 p.P11S 0 129 0.405063 79 WCM199_Z3_1 Tissue 1528412883 C A HERC2 p.D3502Y 0 230 0.064516 217 WCM1_T Tissue 17 7577538C T TP53 p.R248Q 0 100 0.054945 91 WCM1_T Tissue 4 55152038 G A PDGFRAp.V824I 0 491 0.053305 469 WCM1_T Tissue 11 19206549 C A CSRP3 p.S153I 036 0.060241 83 WCM2 Plasma 11 6867517 G A OR10A5 p.V202I 0 36 0.15068573 WCM2 Plasma 12 57598451 A C LRP1 p.N3705H 0 32 0.056818 88 WCM2Plasma 13 45602098 A G GPALPP1 p.N328S 0 54 0.07377 122 WCM2 Plasma 1447343266 G A MDGA2 p.R790C 0 38 0.116505 103 WCM2 Plasma 16 424079 C TTMEM8A p.D610N 0 35 0.094118 85 WCM2 Plasma 19 49926533 G C PTH2 p.L22V0 32 0.058824 85 WCM2 Plasma 5 37121743 C A C5orf42 p.C3000F 0 660.228814 118 WCM2 Plasma 10 84118501 C T NRG3 p.T277M 0 63 0.318182 44WCM201_Z1_1 Tissue 1 110032692 A G ATXN7L2 p.D393G 0 66 0.284483 116WCM201_Z1_1 Tissue 11 123894494 C A OR10G9 p.L259M 0 141 0.203488 172WCM201_Z1_1 Tissue 11 1477725 G A BRSK2 p.G606S 0 141 0.165049 103WCM201_Z1_1 Tissue 1 153410724 C T S100A7L2 p.D39N 0.004831 207 0.09375192 WCM201_Z1_1 Tissue 11 66982825 C G KDM2A p.D167E 0 93 0.358974 78WCM201_Z1_1 Tissue 1 180885828 C T KIAA1614 p.H197Y 0 194 0.129032 186WCM201_Z1_1 Tissue 1 186092324 C G HMCN1 p.S4157R 0 89 0.068376 117WCM201_Z1_1 Tissue 1 201195129 G A IGFN1 p.R3555H 0 55 0.152941 85WCM201_Z1_1 Tissue 12 32136327 C T KIAA1551 p.A813V 0 59 0.084337 83WCM201_Z1_1 Tissue 1 248512142 G T OR14C36 p.Q22H 0 106 0.07 100WCM201_Z1_1 Tissue 12 80943507 G A PTPRQ p.E1423K 0 84 0.079245 265WCM201_Z1_1 Tissue 14 77750142 G A POMT2 p.R551W 0 49 0.453333 75WCM201_Z1_1 Tissue 15 91434792 C G FES p.Y513* 0.009615 104 0.122222 90WCM201_Z1_1 Tissue 16 19711736 C T C16orf62 p.Q944* 0 199 0.364407 236WCM201_Z1_1 Tissue 17 27254014 G C PHF12 p.R106G 0 105 0.268519 108WCM201_Z1_1 Tissue 17 29527473 G A NF1 p.A308T 0 109 0.387755 147WCM201_Z1_1 Tissue 17 56355332 G A MPO p.R354C 0 42 0.267857 56WCM201_Z1_1 Tissue 17 7577505 T A TP53 p.D259V 0 103 0.60396 101WCM201_Z1_1 Tissue 17 76134755 C T TMC8 p.R589C 0 140 0.098039 204WCM201_Z1_1 Tissue 18 76754198 G A SALL3 p.R736H 0 60 0.266667 45WCM201_Z1_1 Tissue 19 46388174 C T IRF2BP1 p.A287T 0 56 0.103448 58WCM201_Z1_1 Tissue 20 49626457 C T KCNG1 p.R140H 0 61 0.061728 81WCM201_Z1_1 Tissue 2 186604169 G A FSIP2 p.V66I 0 52 0.186441 59WCM201_Z1_1 Tissue 4 46053577 G A GABRG1 p.A332V 0 57 0.362069 58WCM201_Z1_1 Tissue 5 153056685 G T GRIA1 p.W331C 0 93 0.131868 91WCM201_Z1_1 Tissue 6 36334526 G T ETV7 p.P308T 0 37 0.478261 46WCM201_Z1_1 Tissue 6 36981471 G A FGD2 p.R205Q 0 117 0.073171 123WCM201_Z1_1 Tissue 7 137148323 G A DGKI p.R891C 0 83 0.317308 104WCM201_Z1_1 Tissue 8 146033125 G A ZNF517 p.R275Q 0 31 0.071429 42WCM201_Z1_1 Tissue 1 169572276 G T SELP p.P565T 0 33 0.057143 70 WCM207Plasma 12 124303504 A G DNAH10 p.D1145G 0 66 0.394737 76 WCM207 Plasma16 72822473 G T ZFHX3 p.D3234E 0 37 0.447368 38 WCM207 Plasma 17 3030034T A OR1G1 p.D271V 0 57 0.752577 97 WCM207 Plasma 17 7579349 A C TP53p.F113C 0 55 0.621212 66 WCM207 Plasma 18 67534634 C T CD226 p.E282K 041 0.618182 55 WCM207 Plasma 19 16279000 C A CIB3 p.M98I 0 40 0.22727366 WCM207 Plasma 19 35505186 C T GRAMD1A p.P322S 0 39 0.375 96 WCM207Plasma 2 183053727 T A PDE1A p.M412L 0 61 0.52439 82 WCM207 Plasma 2202400781 T C ALS2CR11 p.Y490C 0 43 0.383721 86 WCM207 Plasma 2232326373 T C NCL p.D164G 0 38 0.191781 73 WCM207 Plasma 2 232326380 C TNCL p.D162N 0 39 0.180556 72 WCM207 Plasma 5 80638502 T A ACOT12 p.T373S0 61 0.052632 114 WCM207 Plasma 6 166845937 C G RPS6KA2 p.E458D 0 460.211111 90 WCM207 Plasma 6 166845945 C G RPS6KA2 p.E456Q 0 45 0.19780291 WCM207 Plasma 6 56380269 C A DST p.R5865S 0 66 0.436782 87 WCM207Plasma 7 121650401 G T PTPRZ1 p.G434V 0 52 0.336957 92 WCM207 Plasma 9131389743 G A SPTAN1 p.A2214T 0 57 0.396226 106 WCM207 Plasma 9139354245 C T SEC16A p.E1541K 0 31 0.333333 48 WCM207 Plasma 9 96857616G A PTPDC1 p.G158R 0 52 0.428571 91 WCM207 Plasma 1 109395210 A T AKNAD1p.I26N 0.007692 130 0.676768 99 WCM207_X1_1 Tissue 11 118211224 G A CD3Dp.T47M 0 125 0.479452 146 WCM207_X1_1 Tissue 1 112329574 C T KCND3p.A421T 0.007463 134 0.333333 108 WCM207_X1_1 Tissue 1 49005396 G AAGBL4 p.R428W 0 120 0.755725 131 WCM207_X1_1 Tissue 15 42115750 C TMAPKBP1 p.P1241L 0 115 0.478261 46 WCM207_X1_1 Tissue 17 19646602 T GALDH3A1 p.T113P 0 243 0.438095 210 WCM207_X1_1 Tissue 17 3030034 T AOR1G1 p.D271V 0.005495 182 0.988636 88 WCM207_X1_1 Tissue 17 4646643 G AZMYND15 p.R397Q 0 64 0.075 40 WCM207_X1_1 Tissue 17 7579349 A C TP53p.F113C 0 235 0.9 150 WCM207_X1_1 Tissue 18 67534634 C T CD226 p.E282K 0101 0.982143 56 WCM207_X1_1 Tissue 19 16279000 C A CIB3 p.M98I 0 1470.210227 176 WCM207_X1_1 Tissue 19 35505186 C T GRAMD1A p.P322S 0 580.538462 78 WCM207_X1_1 Tissue 19 55785879 A G HSPBP1 p.V176A 0 530.492754 69 WCM207_X1_1 Tissue 2 183053727 T A PDE1A p.M412L 0 960.584615 65 WCM207_X1_1 Tissue 22 24040502 A T RGL4 p.Q455L 0 73 0.5438657 WCM207_X1_1 Tissue 3 138724834 C T PRR23A p.D93N 0 99 0.469388 98WCM207_X1_1 Tissue 6 166844093 C G RPS6KA2 p.D477H 0 82 0.33871 62WCM207_X1_1 Tissue 6 56380269 C A DST p.R5865S 0 125 0.596491 114WCM207_X1_1 Tissue 7 121650401 G T PTPRZ1 p.G434V 0 72 0.507463 67WCM207_X1_1 Tissue 7 16605977 G A LRRC72 p.R156H 0 83 0.096774 62WCM207_X1_1 Tissue 9 104238426 G A TMEM246 p.R317W 0 129 0.48 150WCM207_X1_1 Tissue 9 131389743 G A SPTAN1 p.A2214T 0 91 0.595041 121WCM207_X1_1 Tissue 9 138556089 G A LCN9 p.V60I 0 101 0.509615 104WCM207_X1_1 Tissue 9 139354245 C T SEC16A p.E1541K 0 108 0.52381 126WCM207_X1_1 Tissue X 109695439 G T RGAG1 p.A532S 0 44 0.073171 41WCM207_X1_1 Tissue 11 35211496 G A CD44 p.S184N 0 41 0.375 72 WCM212Plasma 1 247615175 A G OR2B11 p.L37P 0 42 0.168539 89 WCM212 Plasma 1423044016 T A DAD1 p.N110I 0 42 0.055556 72 WCM212 Plasma 16 67974112 C GLCAT p.G340R 0 34 0.087719 57 WCM212 Plasma 16 72141552 A G DHX38p.T940A 0 40 0.317073 82 WCM212 Plasma 19 49003080 G A LMTK3 p.P416S 042 0.070423 71 WCM212 Plasma 2 191923448 G A STAT4 p.A361V 0 120 0.05303132 WCM212 Plasma 2 197948168 C T ANKRD44 p.G436E 0 34 0.058824 102WCM212 Plasma 2 44209481 T C LRPPRC p.N81S 0 38 0.087379 103 WCM212Plasma 5 10236707 T G FAM173B p.K109N 0 39 0.081967 122 WCM212 Plasma 5167855749 G A WWC1 p.E653K 0 42 0.109091 110 WCM212 Plasma 6 144811308 AT UTRN p.R1412S 0 41 0.106383 94 WCM212 Plasma 7 37916520 C T NME8p.A302V 0 54 0.440367 109 WCM212 Plasma 7 48273713 G A ABCA13 p.E288K 041 0.060976 82 WCM212 Plasma 8 17731929 C T FGL1 p.D116N 0 35 0.10714356 WCM212 Plasma 8 9473125 G A TNKS p.R311Q 0 31 0.075472 53 WCM212Plasma 9 32467922 G A DDX58 p.L675F 0 36 0.127273 110 WCM212 Plasma 937744799 G C FRMPD1 p.E924Q 0 31 0.054054 74 WCM212 Plasma 10 13370389 TG SEPHS1 p.Q238P 0 54 0.588235 34 WCM212_Z2_1 Tissue 11 114401609 A GNXPE1 p.S41P 0 70 0.236364 110 WCM212_Z2_1 Tissue 11 123886634 C TOR10G4 p.S118F 0 101 0.160839 143 WCM212_Z2_1 Tissue 11 35211496 G ACD44 p.S184N 0 48 0.357143 42 WCM212_Z2_1 Tissue 1 209849198 C T G0S2p.R57W 0 44 0.555556 45 WCM212_Z2_1 Tissue 1 247615175 A G OR2B11 p.L37P0 34 0.3125 32 WCM212_Z2_1 Tissue 1 248186052 C G OR2L5 p.T268R 0 830.685393 89 WCM212_Z2_1 Tissue 1 40092289 C T HEYL p.V293M 0 1030.527273 55 WCM212_Z2_1 Tissue 14 21813332 A G RPGRIP1 p.N1198S 0 870.25 60 WCM212_Z2_1 Tissue 16 27221835 G C KDM8 p.A131P 0 58 0.338983 59WCM212_Z2_1 Tissue 16 72141552 A G DHX38 p.T940A 0 146 0.414141 99WCM212_Z2_1 Tissue 16 737394 G A WDR24 p.R358C 0 168 0.247059 170WCM212_Z2_1 Tissue 17 39681209 G T KRT19 p.D182E 0 86 0.326733 101WCM212_Z2_1 Tissue 18 11066210 G A PIEZO2 p.R26* 0 163 0.364964 137WCM212_Z2_1 Tissue 19 41800254 G A HNRNPUL1 p.M426I 0 59 0.061538 65WCM212_Z2_1 Tissue 22 41621911 T A L3MBTL2 p.C490* 0 179 0.052941 170WCM212_Z2_1 Tissue 2 73675876 C T ALMS1 p.T740I 0 55 0.193548 31WCM212_Z2_1 Tissue 5 10236707 T G FAM173B p.K109N 0 71 0.178082 73WCM212_Z2_1 Tissue 5 149001606 C A ARHGEF37 p.A439E 0 137 0.272109 147WCM212_Z2_1 Tissue 5 175110957 G A HRH2 p.G241R 0 132 0.392857 140WCM212_Z2_1 Tissue 7 37916520 C T NME8 p.A302V 0 68 0.397727 88WCM212_Z2_1 Tissue 8 11710911 C T CTSB p.R18Q 0 61 0.3125 32 WCM212_Z2_1Tissue 8 144944813 G A EPPK1 p.A870V 0 57 0.270833 48 WCM212_Z2_1 Tissue8 145540305 G A DGAT1 p.S460L 0 81 0.26087 115 WCM212_Z2_1 Tissue 1159577366 G A MRPL16 p.A28V 0 42 0.069767 43 WCM213 Plasma 17 76462868 CT DNAH17 p.V2932M 0 35 0.058824 68 WCM213 Plasma 18 5445164 G A EPB41L3p.T154M 0 42 0.061728 81 WCM213 Plasma 2 208489076 C G METTL21A p.E8D 043 0.059701 67 WCM213 Plasma 2 55436588 G C CLHC1 p.P256A 0 56 0.05555690 WCM213 Plasma 3 49720558 A G APEH p.K691R 0 37 0.09589 73 WCM213Plasma 10 112541631 T C RBM20 p.F422L 0 295 0.083682 239 WCM213_X1_1Tissue 1 109466823 T C GPSM2 p.L601P 0 61 0.410256 39 WCM213_X1_1 Tissue11 10506394 A T AMPD3 p.E215V 0 175 0.116438 146 WCM213_X1_1 Tissue 11124875035 C T CCDC15 p.L780F 0 135 0.113402 97 WCM213_X1_1 Tissue 111255834 G A MUC5B p.E852K 0 173 0.088496 113 WCM213_X1_1 Tissue 1114429257 C A BCL2L15 p.A51S 0 70 0.073171 41 WCM213_X1_1 Tissue 1117741910 G A MYOD1 p.S194N 0 47 0.150943 53 WCM213_X1_1 Tissue 1136597306 G T RAG1 p.V818L 0 145 0.107692 130 WCM213_X1_1 Tissue 1136614203 G A RAG2 p.R506C 0 117 0.138889 108 WCM213_X1_1 Tissue 1171259729 G A KRTAP5-9 p.G9D 0 164 0.081081 111 WCM213_X1_1 Tissue 1176992672 C G ASTN1 p.D436H 0 183 0.087719 228 WCM213_X1_1 Tissue 1179965945 C G CEP350 p.S218C 0 199 0.057692 208 WCM213_X1_1 Tissue 1180012277 G T CEP350 p.Q1483H 0 188 0.066116 121 WCM213_X1_1 Tissue 1185143976 A T SWT1 p.S233C 0 35 0.133333 60 WCM213_X1_1 Tissue 1192085484 G A FAT3 p.G69D 0 49 0.282051 39 WCM213_X1_1 Tissue 12104179177 G C NT5DC3 p.T422R 0 153 0.227273 110 WCM213_X1_1 Tissue 1231131571 A C ARV1 p.K172Q 0 36 0.066667 60 WCM213_X1_1 Tissue 127287982 G T CLSTN3 p.R148L 0 215 0.12069 116 WCM213_X1_1 Tissue 1358207629 C A PCDH17 p.L317M 0 133 0.085714 70 WCM213_X1_1 Tissue 1476123838 C T C14orf1 p.R3H 0 216 0.061644 146 WCM213_X1_1 Tissue 1541146858 T C SPINT1 p.L379P 0 126 0.070707 99 WCM213_X1_1 Tissue 1543695979 G C TUBGCP4 p.Q611H 0 69 0.125 72 WCM213_X1_1 Tissue 1550555481 T G HDC p.D52A 0 197 0.089552 67 WCM213_X1_1 Tissue 16 88691615C T ZC3H18 p.T683M 0 53 0.0625 48 WCM213_X1_1 Tissue 17 1840679 C TRTN4RL1 p.G146D 0 58 0.087719 57 WCM213_X1_1 Tissue 17 2996057 G C OR1D2p.I78M 0 104 0.196721 122 WCM213_X1_1 Tissue 17 60767610 C G MRC2p.S1279C 0 204 0.055814 215 WCM213_X1_1 Tissue 17 79425974 G A RP11-p.A1862T 0 32 0.061224 49 WCM213_X1_1 Tissue 1055B8.7 17 79912150 T CNOTUM p.H389R 0 44 0.107692 65 WCM213_X1_1 Tissue 19 10129542 G A RDH8p.R133Q 0 81 0.120482 83 WCM213_X1_1 Tissue 19 14938182 C G OR7A5p.S291T 0 95 0.180556 72 WCM213_X1_1 Tissue 19 15769192 C T CYP4F3p.R412W 0 111 0.097826 92 WCM213_X1_1 Tissue 19 46443275 A T NOVA2p.I442N 0 115 0.086957 69 WCM213_X1_1 Tissue 19 55687474 C G SYT5 p.E91Q0 123 0.084034 119 WCM213_X1_1 Tissue 20 34091548 A G CEP250 p.Q1784R 0181 0.051813 193 WCM213_X1_1 Tissue 20 56078638 G A CTCFL p.S565L 0 1530.05814 86 WCM213_X1_1 Tissue 20 61950905 A T COL20A1 p.D958V 0 880.066176 136 WCM213_X1_1 Tissue 21 16337311 A C NRIP1 p.L1068R 0 750.061538 65 WCM213_X1_1 Tissue 21 45950952 G A TSPEAR p.R203W 0 1220.066667 120 WCM213_X1_1 Tissue 21 47821593 G C PCNT p.Q1640H 0 2450.107692 260 WCM213_X1_1 Tissue 2 208489076 C G METTL21A p.E8D 0 750.296296 81 WCM213_X1_1 Tissue 2 211541747 A G CPS1 p.S1431G 0 490.105263 38 WCM213_X1_1 Tissue 22 24581790 A G SUSD2 p.Y411C 0 1400.108434 83 WCM213_X1_1 Tissue 22 30074280 G T NF2 p.M514I 0 91 0.05660453 WCM213_X1_1 Tissue 2 55436588 G C CLHC1 p.P256A 0 73 0.102564 78WCM213_X1_1 Tissue 2 55750956 C A CCDC104 p.Q94K 0 95 0.103448 58WCM213_X1_1 Tissue 2 70164394 G A MXD1 p.V116I 0 52 0.096774 62WCM213_X1_1 Tissue 3 124103725 G A KALRN p.A600T 0 88 0.066116 121WCM213_X1_1 Tissue 3 127842441 C T RUVBL1 p.E43K 0 67 0.098901 91WCM213_X1_1 Tissue 3 151166337 C T IGSF10 p.D478N 0 82 0.12069 58WCM213_X1_1 Tissue 3 49720558 A G APEH p.K691R 0 188 0.136364 110WCM213_X1_1 Tissue 3 52185079 C T POC1A p.R19Q 0 89 0.082353 85WCM213_X1_1 Tissue 3 78710186 C G ROBO1 p.E772Q 0 71 0.152941 85WCM213_X1_1 Tissue 4 5468549 C G STK32B p.D343E 0 32 0.071429 42WCM213_X1_1 Tissue 4 6083352 C T JAKMIP1 p.R362Q 0 81 0.078947 76WCM213_X1_1 Tissue 4 73184410 C T ADAMTS3 p.C455Y 0 94 0.155844 77WCM213_X1_1 Tissue 5 154181813 C T LARP1 p.R578W 0 52 0.108696 46WCM213_X1_1 Tissue 5 156899352 T G NIPAL4 p.F262C 0 81 0.093333 75WCM213_X1_1 Tissue 5 35875633 C A IL7R p.P274T 0 186 0.051852 135WCM213_X1_1 Tissue 5 38493725 T C LIFR p.E683G 0 72 0.084507 71WCM213_X1_1 Tissue 5 66462008 C G MAST4 p.P2334R 0 219 0.167598 179WCM213_X1_1 Tissue 7 100210427 G C MOSPD3 p.A5P 0 103 0.10084 119WCM213_X1_1 Tissue 7 99197857 T A GS1- p.F55I 0 212 0.126126 222WCM213_X1_1 Tissue 259H13.10 8 131848572 C T ADCY8 p.V876I 0 1790.326693 251 WCM213_X1_1 Tissue 9 115422224 C T KIAA1958 p.R676C 0 1630.168539 89 WCM213_X1_1 Tissue 9 35044247 G C C9orf131 p.A541P 0 1720.217822 101 WCM213_X1_1 Tissue 9 37782031 A G EXOSC3 p.I193T 0 2330.109827 173 WCM213_X1_1 Tissue X 22292264 G T ZNF645 p.D386Y 0 450.149254 67 WCM213_X1_1 Tissue X 53566676 G C HUWE1 p.D3858E 0 440.246575 73 WCM213_X1_1 Tissue X 74332773 G T ABCB7 p.T94K 0 81 0.07042371 WCM213_X1_1 Tissue 10 112541631 T C RBM20 p.F422L 0 295 0.114068 263WCM213_Z13_1 Tissue 10 124345687 A T DMBT1 p.D524V 0 107 0.083969 131WCM213_Z13_1 Tissue 10 47669115 G T ANTXRL p.G235C 0 78 0.063636 110WCM213_Z13_1 Tissue 10 95993933 G A PLCE1 p.R693H 0 63 0.076923 52WCM213_Z13_1 Tissue 1 109466823 T C GPSM2 p.L601P 0 61 0.219512 41WCM213_Z13_1 Tissue 11 124875035 C T CCDC15 p.L780F 0 135 0.091954 87WCM213_Z13_1 Tissue 11 1255834 G A MUC5B p.E852K 0 173 0.080169 237WCM213_Z13_1 Tissue 11 36597306 G T RAG1 p.V818L 0 145 0.103448 145WCM213_Z13_1 Tissue 11 36614203 G A RAG2 p.R506C 0 117 0.150327 153WCM213_Z13_1 Tissue 1 149877492 C T SV2A p.S662N 0 141 0.052632 114WCM213_Z13_1 Tissue 1 166974600 G T MAEL p.D271Y 0 49 0.060606 66WCM213_Z13_1 Tissue 11 71259729 G A KRTAP5-9 p.G9D 0 164 0.054795 146WCM213_Z13_1 Tissue 1 176992672 C G ASTN1 p.D436H 0 183 0.060345 232WCM213_Z13_1 Tissue 1 185143976 A T SWT1 p.S233C 0 35 0.181818 55WCM213_Z13_1 Tissue 11 92085484 G A FAT3 p.G69D 0 49 0.27027 37WCM213_Z13_1 Tissue 12 102108390 A T CHPT1 p.Q177L 0 43 0.125 32WCM213_Z13_1 Tissue 12 104179177 G C NT5DC3 p.T422R 0 153 0.141892 148WCM213_Z13_1 Tissue 1 22902925 C G EPHA8 p.Y125* 0 110 0.074324 148WCM213_Z13_1 Tissue 12 49391127 T C DDN p.Q511R 0 145 0.07619 105WCM213_Z13_1 Tissue 12 58020708 C G B4GALNT1 p.G474A 0 151 0.0625 112WCM213_Z13_1 Tissue 12 7287982 G T CLSTN3 p.R148L 0 215 0.097561 164WCM213_Z13_1 Tissue 12 91445224 G A KERA p.P320S 0 170 0.0875 240WCM213_Z13_1 Tissue 13 39438625 C T FREM2 p.T2622I 0 81 0.08 75WCM213_Z13_1 Tissue 1 42047861 C G HIVEP3 p.E870Q 0 116 0.075 120WCM213_Z13_1 Tissue 14 21860859 G C CHD8 p.P2193R 0 146 0.126316 95WCM213_Z13_1 Tissue 1 46740310 C A RAD54L p.P597Q 0 123 0.084034 119WCM213_Z13_1 Tissue 15 41146858 T C SPINT1 p.L379P 0 126 0.124224 161WCM213_Z13_1 Tissue 15 50534866 T A HDC p.Q527L 0 129 0.125874 143WCM213_Z13_1 Tissue 15 50555481 T G HDC p.D52A 0 197 0.073171 82WCM213_Z13_1 Tissue 16 14721013 A G PARN p.F93L 0 230 0.274286 350WCM213_Z13_1 Tissue 16 30409820 C G ZNF48 p.P417A 0 70 0.05814 86WCM213_Z13_1 Tissue 16 57741445 A C CCDC135 p.K311T 0 80 0.061856 97WCM213_Z13_1 Tissue 1 68512503 C G DIRAS3 p.E160Q 0 103 0.055556 90WCM213_Z13_1 Tissue 17 2996057 G C OR1D2 p.I78M 0 104 0.160377 106WCM213_Z13_1 Tissue 17 53045790 C A COX11 p.R73L 0 109 0.089041 146WCM213_Z13_1 Tissue 18 5445164 G A EPB41L3 p.T154M 0 34 0.38983 59WCM213_Z13_1 Tissue 19 14938182 C G OR7A5 p.S291T 0 95 0.117647 85WCM213_Z13_1 Tissue 19 15769192 C T CYP4F3 p.R412W 0 111 0.066667 120WCM213_Z13_1 Tissue 19 2438190 G C LMNB2 p.L199V 0 155 0.06383 94WCM213_Z13_1 Tissue 19 42909569 C T LIPE p.R837H 0 62 0.112903 62WCM213_Z13_1 Tissue 19 48047729 G C ZNF541 p.T686S 0 39 0.130435 46WCM213_Z13_1 Tissue 19 55672534 G A DNAAF3 p.R271C 0 45 0.135135 37WCM213_Z13_1 Tissue 19 55687474 C G SYT5 p.E91Q 0 123 0.072464 138WCM213_Z13_1 Tissue 20 25203492 T C ENTPD6 p.L355P 0 143 0.060976 164WCM213_Z13_1 Tissue 20 55968347 G C RBM38 p.G125A 0 136 0.055556 162WCM213_Z13_1 Tissue 20 56078638 G A CTCFL p.S565L 0 153 0.070234 299WCM213_Z13_1 Tissue 2 113591074 C A IL1B p.G60C 0 238 0.148594 249WCM213_Z13_1 Tissue 21 31654507 G C KRTAP24-1 p.S248R 0 124 0.050562 178WCM213_Z13_1 Tissue 21 47821593 G C PCNT p.Q1640H 0 245 0.120521 307WCM213_Z13_1 Tissue 2 207170837 A G ZDBF2 p.K529E 0 112 0.114035 114WCM213_Z13_1 Tissue 2 208489076 C G METTL21A p.E8D 0 75 0.49 100WCM213_Z13_1 Tissue 2 20974602 G C C2orf43 p.L146V 0 39 0.109091 55WCM213_Z13_1 Tissue 22 24581790 A G SUSD2 p.Y411C 0 140 0.140625 128WCM213_Z13_1 Tissue 22 30888539 T C SEC14L4 p.K196E 0 96 0.094828 116WCM213_Z13_1 Tissue 22 40718868 G T TNRC6B p.G1709* 0 163 0.058824 170WCM213_Z13_1 Tissue 2 64147683 C T VPS54 p.E650K 0 81 0.230769 39WCM213_Z13_1 Tissue 3 119013771 A T ARHGAP31 p.K7M 0 72 0.054264 129WCM213_Z13_1 Tissue 3 119013772 G T ARHGAP31 p.K7N 0 71 0.054264 129WCM213_Z13_1 Tissue 3 124103725 G A KALRN p.A600T 0 88 0.098039 102WCM213_Z13_1 Tissue 3 151165013 C T IGSF10 p.R919K 0 114 0.128205 78WCM213_Z13_1 Tissue 3 151166136 C T IGSF10 p.D545N 0 109 0.1 70WCM213_Z13_1 Tissue 3 151166337 C T IGSF10 p.D478N 0 82 0.098765 81WCM213_Z13_1 Tissue 3 33438622 C T UBP1 p.D396N 0 73 0.061947 113WCM213_Z13_1 Tissue 3 39130778 T A WDR48 p.V546E 0 56 0.083333 72WCM213_Z13_1 Tissue 3 49720558 A G APEH p.K691R 0 188 0.303226 155WCM213_Z13_1 Tissue 3 50412231 G A CACNA2D2 p.L641F 0 114 0.078947 76WCM213_Z13_1 Tissue 3 78710186 C G ROBO1 p.E772Q 0 71 0.144928 69WCM213_Z13_1 Tissue 4 38995570 G A TMEM156 p.S136L 0 75 0.220588 68WCM213_Z13_1 Tissue 5 140250171 G C PCDHA11 p.E495Q 0 83 0.081081 37WCM213_Z13_1 Tissue 5 156899352 T G NIPAL4 p.F262C 0 81 0.089431 123WCM213_Z13_1 Tissue 6 43030670 G T KLC4 p.A92S 0 34 0.135135 37WCM213_Z13_1 Tissue 7 100210427 G C MOSPD3 p.A5P 0 103 0.209302 129WCM213_Z13_1 Tissue 7 21920465 C A DNAH11 p.T4114N 0 94 0.082353 85WCM213_Z13_1 Tissue 7 28547258 T A CREB5 p.F65Y 0 175 0.051852 135WCM213_Z13_1 Tissue 7 73151347 G C ABHD11 p.L243V 0 54 0.056075 107WCM213_Z13_1 Tissue 7 98638151 C A SMURF1 p.G493V 0 223 0.082353 255WCM213_Z13_1 Tissue 8 12956025 G T DLC1 p.S1017* 0 84 0.148936 47WCM213_Z13_1 Tissue 8 131848572 C T ADCY8 p.V876I 0 179 0.335294 340WCM213_Z13_1 Tissue 8 142204286 G C DENND3 p.G1184A 0 198 0.157895 171WCM213_Z13_1 Tissue 8 144696811 C G TSTA3 p.M149I 0 102 0.051948 154WCM213_Z13_1 Tissue 8 38205084 C G WHSC1L1 p.K202N 0 109 0.075758 198WCM213_Z13_1 Tissue 9 115422224 C T KIAA1958 p.R676C 0 163 0.333333 117WCM213_Z13_1 Tissue 9 35044247 G C C9orf131 p.A541P 0 172 0.295775 213WCM213_Z13_1 Tissue 9 43627264 G A SPATA31A6 p.R475C 0 137 0.090278 144WCM213_Z13_1 Tissue X 22292264 G T ZNF645 p.D386Y 0 45 0.228571 70WCM213_Z13_1 Tissue X 591805 A G SHOX p.D58G 0 100 0.079268 164WCM213_Z13_1 Tissue 1 2435680 G T PLCH2 p.R1093S 0 35 0.085714 35 WCM216Plasma 4 154556695 G T KIAA0922 p.W1509L 0 43 0.070175 57 WCM216 Plasma1 159784043 G T FCRL6 p.V370F 0 143 0.052632 152 WCM216_Z1_1 Tissue 1173104941 C T RELT p.R229C 0 75 0.076923 78 WCM216_Z1_1 Tissue 4 88016069C A AFF1 p.Q404K 0 67 0.086957 69 WCM216_Z1_1 Tissue 7 56156627 C TPHKG1 p.R3Q 0 45 0.075 40 WCM216_Z1_1 Tissue 11 125267864 G T PKNOX2p.C165F 0 34 0.075 40 WCM218 Plasma 15 43769897 C A TP53BP1 p.Q278H 0 430.063291 79 WCM218 Plasma 15 43783909 C G TP53BP1 p.S105T 0 46 0.09615452 WCM218 Plasma 15 43783910 T C TP53BP1 p.S105G 0 46 0.1 50 WCM218Plasma 10 70229791 G C DNA2 p.I68M 0 73 0.321429 56 WCM218_Z11_1 Tissue11 1101093 A G MUC2 p.T2498A 0 65 0.196429 56 WCM218_Z11_1 Tissue 11118769761 C T BCL9L p.R1288H 0 139 0.25 116 WCM218_Z11_1 Tissue 1133589733 G A KIAA1549L p.R110OQ 0 141 0.272727 176 WCM218_Z11_1 Tissue11 3661512 C A ART5 p.K49N 0 69 0.2 110 WCM218_Z11_1 Tissue 11 46564357A T AMBRA1 p.S404T 0 163 0.2657 207 WCM218_Z11_1 Tissue 1 21053505 C TSH2D5 p.G78R 0 59 0.060606 66 WCM218_Z11_1 Tissue 12 113737742 C ASLC8B1 p.G532V 0 245 0.374016 254 WCM218_Z11_1 Tissue 12 29640802 C GOVCH1 p.G239A 0 38 0.171429 35 WCM218_Z11_1 Tissue 12 55357585 A GTESPA1 p.L199P 0 97 0.218543 151 WCM218_Z11_1 Tissue 12 57601911 G ALRP1 p.V3984M 0 80 0.082353 85 WCM218_Z11_1 Tissue 12 6637175 G C NCAPD2p.V1021L 0 153 0.152381 105 WCM218_Z11_1 Tissue 14 38091823 G A TTC6p.R185H 0 55 0.283019 53 WCM218_Z11_1 Tissue 1 51871579 G C EPS15p.P559A 0 273 0.092437 238 WCM218_Z11_1 Tissue 15 76018504 C G ODF3L1p.S112C 0 136 0.06962 158 WCM218_Z11_1 Tissue 16 3406074 T A OR2C1p.I45N 0 79 0.235849 106 WCM218_Z11_1 Tissue 16 58619368 A T CNOT1p.L227* 0 106 0.075758 66 WCM218_Z11_1 Tissue 17 19470440 G T SLC47A1p.G403V 0 263 0.238462 130 WCM218_Z11_1 Tissue 17 27208908 T C FLOT2p.K280E 0 173 0.178571 140 WCM218_Z11_1 Tissue 17 3352424 T A SPATA22p.N117Y 0 103 0.365385 104 WCM218_Z11_1 Tissue 17 78313184 C G RNF213p.L1673V 0 111 0.22973 148 WCM218_Z11_1 Tissue 17 7951863 G A ALOX15Bp.E671K 0 135 0.306122 98 WCM218_Z11_1 Tissue 19 17323072 C T MYO9Bp.P2143S 0 36 0.212121 33 WCM218_Z11_1 Tissue 19 17688896 G A COLGALT1p.E422K 0 105 0.293578 109 WCM218_Z11_1 Tissue 19 53612278 C A ZNF415p.R340S 0 88 0.211111 90 WCM218_Z11_1 Tissue 19 6935074 C A EMR1 p.T789K0 114 0.254902 102 WCM218_Z11_1 Tissue 20 44641941 C T MMP9 p.Q460* 0138 0.204762 210 WCM218_Z11_1 Tissue 2 112939442 G C FBLN7 p.S220T 0 1190.410526 95 WCM218_Z11_1 Tissue 2 128932419 T C UGGT1 p.Y1176H 0 610.163462 104 WCM218_Z11_1 Tissue 2 225639690 G T DOCK10 p.P1982H 0 480.178571 84 WCM218_Z11_1 Tissue 3 115561378 G A LSAMP p.R233* 0 92 0.265 WCM218_Z11_1 Tissue 3 38153837 C A DLEC1 p.D1217E 0 264 0.141689 367WCM218_Z11_1 Tissue 3 48617487 G T COL7A1 p.P1701T 0 75 0.283333 60WCM218_Z11_1 Tissue 3 49166488 G T LAMB2 p.H566N 0 52 0.21875 32WCM218_Z11_1 Tissue 3 50685395 C T MAPKAPK3 p.T356I 0 208 0.272727 187WCM218_Z11_1 Tissue 3 77666743 G T ROBO2 p.D1125Y 0 124 0.253521 142WCM218_Z11_1 Tissue 4 119252953 G T PRSS12 p.H297N 0 179 0.34728 239WCM218_Z11_1 Tissue 4 141600909 C A TBC1D9 p.R150M 0 110 0.345238 168WCM218_Z11_1 Tissue 5 180047942 G A FLT4 p.R745C 0 40 0.130435 46WCM218_Z11_1 Tissue 6 30672288 C A MDC1 p.G1558C 0 225 0.061111 180WCM218_Z11_1 Tissue 7 149129873 G A ZNF777 p.P497L 0 125 0.254545 55WCM218_Z11_1 Tissue 7 155301708 C G CNPY1 p.D9H 0 125 0.297778 225WCM218_Z11_1 Tissue 7 37960642 G T EPDR1 p.G34V 0 31 0.104167 48WCM218_Z11_1 Tissue 8 101146260 T C FBXO43 p.T633A 0 119 0.089888 89WCM218_Z11_1 Tissue 8 104898333 G C RIMS2 p.K280N 0 74 0.197802 91WCM218_Z11_1 Tissue 8 106813685 A G ZFPM2 p.T459A 0 112 0.44186 86WCM218_Z11_1 Tissue 8 107782084 G A ABRA p.T112M 0 64 0.324561 114WCM218_Z11_1 Tissue 8 67577813 C A VCPIP1 p.V461L 0 88 0.212121 99WCM218_Z11_1 Tissue 9 125377338 G A OR1Q1 p.A108T 0 112 0.102041 98WCM218_Z11_1 Tissue 9 97082767 T C NUTM2F p.Q364R 0 59 0.123077 130WCM218_Z11_1 Tissue X 130408142 G A IGSF1 p.R1264* 0 71 0.583333 108WCM218_Z11_1 Tissue 10 70229791 G C DNA2 p.I68M 0 73 0.2 75 WCM218_Z3_1Tissue 11 103797726 G A PDGFD p.R301C 0 103 0.330579 121 WCM218_Z3_1Tissue 11 1101093 A G MUC2 p.T2498A 0 65 0.371429 35 WCM218_Z3_1 Tissue11 118769761 C T BCL9L p.R1288H 0 139 0.346457 127 WCM218_Z3_1 Tissue 1133589733 G A KIAA1549L p.R110OQ 0 141 0.373913 115 WCM218_Z3_1 Tissue 113661512 C A ART5 p.K49N 0 69 0.189474 95 WCM218_Z3_1 Tissue 11 46564357A T AMBRA1 p.S404T 0 163 0.293706 143 WCM218_Z3_1 Tissue 1 182845272 G ADHX9 p.E635K 0 31 0.162791 43 WCM218_Z3_1 Tissue 12 113737742 C A SLC8B1p.G532V 0 245 0.458194 299 WCM218_Z3_1 Tissue 12 29640802 C G OVCH1p.G239A 0 38 0.229167 48 WCM218_Z3_1 Tissue 1 234744504 G A IRF2BP2p.A246V 0 57 0.084746 59 WCM218_Z3_1 Tissue 12 55357585 A G TESPA1p.L199P 0 97 0.130841 107 WCM218_Z3_1 Tissue 1 37346322 C T GRIK3p.D155N 0 51 0.341463 41 WCM218_Z3_1 Tissue 14 38091823 G A TTC6 p.R185H0 55 0.234043 47 WCM218_Z3_1 Tissue 1 51871579 G C EPS15 p.P559A 0 2730.174699 166 WCM218_Z3_1 Tissue 15 76018504 C G ODF3L1 p.S112C 0 1360.164835 91 WCM218_Z3_1 Tissue 16 3406074 T A OR2C1 p.I45N 0 79 0.21333375 WCM218_Z3_1 Tissue 16 58619317 C G CNOT1 p.G244A 0 43 0.078431 51WCM218_Z3_1 Tissue 16 58619368 A T CNOT1 p.L227* 0 106 0.08 100WCM218_Z3_1 Tissue 16 67655363 G A CTCF p.C409Y 0 191 0.055866 179WCM218_Z3_1 Tissue 17 19470440 G T SLC47A1 p.G403V 0 263 0.275109 229WCM218_Z3_1 Tissue 17 3352424 T A SPATA22 p.N117Y 0 103 0.357895 95WCM218_Z3_1 Tissue 17 78313184 C G RNF213 p.L1673V 0 111 0.266187 139WCM218_Z3_1 Tissue 17 7951863 G A ALOX15B p.E671K 0 135 0.259259 81WCM218_Z3_1 Tissue 19 17323072 C T MYO9B p.P2143S 0 36 0.205128 39WCM218_Z3_1 Tissue 19 17688896 G A COLGALT1 p.E422K 0 105 0.241758 91WCM218_Z3_1 Tissue 19 41179380 C T NUMBL p.R302H 0 61 0.0625 96WCM218_Z3_1 Tissue 19 53612278 C A ZNF415 p.R340S 0 88 0.326087 92WCM218_Z3_1 Tissue 19 6935074 C A EMR1 p.T789K 0 114 0.413793 58WCM218_Z3_1 Tissue 20 44641941 C T MMP9 p.Q460* 0 138 0.24812 133WCM218_Z3_1 Tissue 2 112939442 G C FBLN7 p.S220T 0 119 0.421053 95WCM218_Z3_1 Tissue 2 128932419 T C UGGT1 p.Y1176H 0 61 0.294118 68WCM218_Z3_1 Tissue 2 225639690 G T DOCK10 p.P1982H 0 48 0.418182 55WCM218_Z3_1 Tissue 3 115561378 G A LSAMP p.R233* 0 92 0.273684 95WCM218_Z3_1 Tissue 3 48617487 G T COL7A1 p.P1701T 0 75 0.169492 59WCM218_Z3_1 Tissue 3 50685395 C T MAPKAPK3 p.T356I 0 208 0.238095 189WCM218_Z3_1 Tissue 3 53857923 C T CHDH p.R38Q 0 47 0.282051 39WCM218_Z3_1 Tissue 3 77666743 G T ROBO2 p.D1125Y 0 124 0.243243 111WCM218_Z3_1 Tissue 4 119252953 G T PRSS12 p.H297N 0 179 0.414365 181WCM218_Z3_1 Tissue 4 141600909 C A TBC1D9 p.R150M 0 110 0.31405 121WCM218_Z3_1 Tissue 5 140176608 G A PCDHA2 p.A687T 0 78 0.333333 45WCM218_Z3_1 Tissue 5 150639352 G A GM2A p.D40N 0 158 0.330357 112WCM218_Z3_1 Tissue 6 108645100 G A LACE1 p.V71I 0 38 0.360656 61WCM218_Z3_1 Tissue 6 152754970 G T SYNE1 p.T1474N 0 93 0.105263 57WCM218_Z3_1 Tissue 7 149129873 G A ZNF777 p.P497L 0 125 0.219697 132WCM218_Z3_1 Tissue 7 155301708 C G CNPY1 p.D9H 0 125 0.266667 195WCM218_Z3_1 Tissue 8 101146260 T C FBXO43 p.T633A 0 119 0.177305 141WCM218_Z3_1 Tissue 8 104898333 G C RIMS2 p.K280N 0 74 0.273973 73WCM218_Z3_1 Tissue 8 106813685 A G ZFPM2 p.T459A 0 112 0.411348 141WCM218_Z3_1 Tissue 8 107782084 G A ABRA p.T112M 0 64 0.227273 66WCM218_Z3_1 Tissue 8 145773124 C A ARHGAP39 p.S449I 0 47 0.148148 54WCM218_Z3_1 Tissue 8 67577813 C A VCPIP1 p.V461L 0 88 0.186916 107WCM218_Z3_1 Tissue 8 82606504 G C SLC10A5 p.A235G 0 67 0.2 80WCM218_Z3_1 Tissue 9 118950348 G A PAPPA p.R444H 0 116 0.139344 122WCM218_Z3_1 Tissue 9 72892345 C T SMC5 p.A167V 0 38 0.262295 61WCM218_Z3_1 Tissue 9 97082767 T C NUTM2F p.Q364R 0 59 0.181818 77WCM218_Z3_1 Tissue X 130408142 G A IGSF1 p.R1264* 0 71 0.46 50WCM218_Z3_1 Tissue X 38031221 A G SRPX p.C147R 0 95 0.069444 72WCM218_Z3_1 Tissue 15 43748917 C G TP53BP1 p.S625T 0 41 0.090909 44WCM219 Plasma 15 43748918 T C TP53BP1 p.S625G 0 41 0.093023 43 WCM219Plasma 2 191382331 G T TMEM194B p.T176N 0 54 0.088235 34 WCM219 Plasma15 43712787 T C TP53BP1 p.D1461G 0 34 0.076923 39 WCM223 Plasma 10101716269 G A DNMBP p.P321L 0 140 0.09375 64 WCM223_Z2_1 Tissue 1052103403 C T SGMS1 p.E158K 0 166 0.054795 146 WCM223_Z2_1 Tissue 110725506 G A CASZ1 p.R47* 0 76 0.106061 66 WCM223_Z2_1 Tissue 11118211295 C A CD3D p.K23N 0 59 0.191176 68 WCM223_Z2_1 Tissue 1120437527 G T ADAM30 p.P478Q 0 80 0.095238 63 WCM223_Z2_1 Tissue 1181687235 T C CACNA1E p.S524P 0 60 0.403226 62 WCM223_Z2_1 Tissue 1250747833 C G FAM186A p.G928R 0 115 0.333333 63 WCM223_Z2_1 Tissue 1438061191 G C FOXA1 p.F266L 0 67 0.571429 63 WCM223_Z2_1 Tissue 146660039 G T POMGNT1 p.N262K 0 95 0.060606 66 WCM223_Z2_1 Tissue 1549031309 C A CEP152 p.E1424* 0 42 0.5 46 WCM223_Z2_1 Tissue 1 66723353 CG PDE4B p.T167S 0 74 0.070588 85 WCM223_Z2_1 Tissue 17 19284298 G AMAPK7 p.R259H 0 96 0.402985 67 WCM223_Z2_1 Tissue 1 75037558 G AC1orf173 p.P1279L 0 87 0.253521 71 WCM223_Z2_1 Tissue 20 2464746 G TZNF343 p.H287Q 0 85 0.086957 69 WCM223_Z2_1 Tissue 21 43166326 C T RIPK4p.G280R 0 95 0.393443 61 WCM223_Z2_1 Tissue 2 179486277 C T TTNp.A13451T 0 49 0.8 35 WCM223_Z2_1 Tissue 4 158254023 G A GRIA2 p.R312H 0248 0.387931 116 WCM223_Z2_1 Tissue 4 158257722 G C GRIA2 p.G556A 0 1530.649123 57 WCM223_Z2_1 Tissue 5 96126063 G C ERAP1 p.P487R 0 840.560976 82 WCM223_Z2_1 Tissue 6 152461140 C T SYNE1 p.R8468H 0 1010.132075 53 WCM223_Z2_1 Tissue 6 34029684 G T GRM4 p.N286K 0 106 0.07580 WCM223_Z2_1 Tissue 7 82583461 C A PCLO p.A2270S 0 33 0.076923 39WCM223_Z2_1 Tissue 8 132052522 G T ADCY8 p.P20T 0 124 0.536585 41WCM223_Z2_1 Tissue 8 133650275 T C LRRC6 p.N112S 0 134 0.3 50WCM223_Z2_1 Tissue 8 21983191 C T HR p.C487Y 0 217 0.467626 139WCM223_Z2_1 Tissue 8 89128849 T G MMP16 p.K324Q 0 61 0.092308 65WCM223_Z2_1 Tissue X 142967267 G C UBE2NL p.G22A 0 53 0.942857 35WCM223_Z2_1 Tissue X 69368672 G T IGBP1 p.R247L 0 67 0.066667 45WCM223_Z2_1 Tissue 11 108382276 A G EXPH5 p.S1320P 0 90 0.85 60WCM223_Z4_1 Tissue 1 158576737 G T OR10Z1 p.S170I 0 343 0.29703 202WCM223_Z4_1 Tissue 11 76868342 C A MYO7A p.N251K 0 264 0.428571 238WCM223_Z4_1 Tissue 12 50392983 T G RACGAP1 p.S274R 0 134 0.368932 103WCM223_Z4_1 Tissue 1 3644315 C A TP73 p.N322K 0 92 0.081081 74WCM223_Z4_1 Tissue 1 43634636 G A EBNA1BP2 p.R171* 0 258 0.564246 179WCM223_Z4_1 Tissue 17 19284298 G A MAPK7 p.R259H 0 169 0.404762 126WCM223_Z4_1 Tissue 17 34934417 T C GGNBP2 p.C216R 0 70 0.4 80WCM223_Z4_1 Tissue 18 8784557 G A SOGA2 p.G843R 0 172 0.426829 164WCM223_Z4_1 Tissue 2 128865631 G A UGGT1 p.A133T 0 114 0.111111 54WCM223_Z4_1 Tissue 21 45993654 G A KRTAP10-4 p.D7N 0 157 0.490566 106WCM223_Z4_1 Tissue 2 69093011 C T BMP10 p.A343T 0 44 0.452991 117WCM223_Z4_1 Tissue 4 158254023 G A GRIA2 p.R312H 0 174 0.494737 190WCM223_Z4_1 Tissue 5 73197014 G T ARHGEF28 p.V1327F 0 162 0.089552 67WCM223_Z4_1 Tissue 8 132052522 G T ADCY8 p.P20T 0 222 0.49635 137WCM223_Z4_1 Tissue 8 87162356 C T ATP6V0D2 p.R219C 0 80 0.347826 92WCM223_Z4_1 Tissue X 142967267 G C UBE2NL p.G22A 0 46 0.942308 52WCM223_Z4_1 Tissue 19 49238557 C T RASIP1 p.G359R 0 36 0.095745 94WCM243 Plasma 1 152275808 C G FLG p.G3852R 0 68 0.215909 88 WCM243_X1_1Tissue 11 55927030 A C OR8K5 p.L255R 0 172 0.105991 217 WCM243_X1_1Tissue 11 56000198 G T OR5T2 p.A155D 0 81 0.12766 94 WCM243_X1_1 Tissue11 6898584 C T OR10A4 p.H236Y 0 127 0.331034 145 WCM243_X1_1 Tissue 12114836461 C T TBX5 p.A143T 0 143 0.374408 211 WCM243_X1_1 Tissue 12121176678 G A ACADS p.R330H 0 162 0.151515 198 WCM243_X1_1 Tissue 1231334860 G A TRIM67 p.R403H 0 101 0.276596 94 WCM243_X1_1 Tissue 14105404579 G A AHNAK2 p.R5737* 0 199 0.165854 205 WCM243_X1_1 Tissue 1458909548 G A KIAA0586 p.V164M 0 66 0.391304 46 WCM243_X1_1 Tissue 1585326151 A C ZNF592 p.E82A 0 81 0.245614 57 WCM243_X1_1 Tissue 1586838635 G T AGBL1 p.Q744H 0 219 0.051948 154 WCM243_X1_1 Tissue 1627709753 G T KIAA0556 p.V349L 0 63 0.060606 66 WCM243_X1_1 Tissue 163367592 A G ZNF75A p.N205S 0 92 0.260274 73 WCM243_X1_1 Tissue 17 650490A G GEMIN4 p.Y265H 0 197 0.099415 171 WCM243_X1_1 Tissue 1 78178939 A CUSP33 p.I779S 0 32 0.142857 35 WCM243_X1_1 Tissue 19 17598085 C TSLC27A1 p.P222L 0 51 0.075472 53 WCM243_X1_1 Tissue 19 49238557 C TRASIP1 p.G359R 0 58 0.471698 53 WCM243_X1_1 Tissue 20 57767362 C TZNF831 p.R430W 0 44 0.054795 73 WCM243_X1_1 Tissue 2 179395177 T C TTNp.I33748V 0 129 0.294643 112 WCM243_X1_1 Tissue 2 20482930 G A PUM2p.R500W 0 109 0.313726 51 WCM243_X1_1 Tissue 3 129269965 G T H1FOOp.A275S 0 73 0.201923 104 WCM243_X1_1 Tissue 3 37512512 C T ITGA9 p.A67V0 81 0.122222 90 WCM243_X1_1 Tissue 3 49679897 G A BSN p.R277H 0 330.275 40 WCM243_X1_1 Tissue 4 100574365 G A RP11- p.P481S 0 65 0.10869646 WCM243_X1_1 Tissue 766F14.2 5 176700724 T A NSD1 p.L1854Q 0 1200.189024 164 WCM243_X1_1 Tissue 6 139694804 A T CITED2 p.F93Y 0 660.507246 69 WCM243_X1_1 Tissue 7 128485276 G A FLNC p.V1253I 0 1310.141553 219 WCM243_X1_1 Tissue 7 128490514 C T FLNC p.A1792V 0 1100.312139 173 WCM243_X1_1 Tissue 7 148863929 G T ZNF398 p.D190Y 0 790.168142 113 WCM243_X1_1 Tissue 9 139399507 C A NOTCH1 p.D1546Y 0 690.507246 69 WCM243_X1_1 Tissue 9 34256113 G T KIF24 p.H1164Q 0 570.074627 67 WCM243_X1_1 Tissue 12 117612522 C T FBXO21 p.V225M 0 340.1125 80 WCM247 Plasma 5 140202639 C T PCDHA5 p.R427W 0 31 0.092593 108WCM247 Plasma 8 56436599 G A XKR4 p.R589Q 0 37 0.065934 91 WCM247 Plasma10 105836152 A T COL17A1 p.Y80N 0 111 0.197368 76 WCM247_Z9_1 Tissue 1117099184 C G RPS13 p.G2A 0 146 0.108527 129 WCM247_Z9_1 Tissue 1157512685 C T FCRL5 p.A363T 0 151 0.184049 163 WCM247_Z9_1 Tissue 1178433758 C A TENM4 p.R1252I 0 85 0.105691 123 WCM247_Z9_1 Tissue 1183221781 C T NMNAT2 p.G307S 0 93 0.245283 106 WCM247_Z9_1 Tissue 12117612522 C T FBXO21 p.V225M 0 177 0.278607 201 WCM247_Z9_1 Tissue 1229908650 T G TMTC1 p.Q241H 0 63 0.135135 37 WCM247_Z9_1 Tissue 144071048 C T PTPRF p.S1108F 0 99 0.275 120 WCM247_Z9_1 Tissue 1584237376 G T SH3GL3 p.D95Y 0 130 0.080645 62 WCM247_Z9_1 Tissue 1684922899 G A CRISPLD2 p.V457M 0 83 0.125 104 WCM247_Z9_1 Tissue 1689977048 C G TCF25 p.L617V 0 77 0.133333 60 WCM247_Z9_1 Tissue 1757287675 C G SMG8 p.P88R 0 86 0.244898 49 WCM247_Z9_1 Tissue 17 7577580T C TP53 p.Y234C 0 204 0.243421 152 WCM247_Z9_1 Tissue 1 93683398 A TCCDC18 p.H644L 0 45 0.088889 45 WCM247_Z9_1 Tissue 19 46998691 C TPNMAL2 p.R11Q 0 90 0.089552 67 WCM247_Z9_1 Tissue 2 101885703 T A CNOT11p.V454E 0 31 0.228571 35 WCM247_Z9_1 Tissue 2 23865523 G A KLHL29p.G248E 0 35 0.571429 42 WCM247_Z9_1 Tissue 3 123014966 A G ADCY5p.S1010P 0 91 0.162162 74 WCM247_Z9_1 Tissue 3 43074492 C T FAM198Ap.T246M 0 120 0.282609 92 WCM247_Z9_1 Tissue 3 47044007 C G NBEAL2p.F1766L 0 46 0.209302 43 WCM247_Z9_1 Tissue 3 63981669 C T ATXN7p.S724F 0 95 0.254545 110 WCM247_Z9_1 Tissue 3 9798237 G A OGG1 p.R277H0 212 0.18408 201 WCM247_Z9_1 Tissue 5 140202639 C T PCDHA5 p.R427W 0126 0.19685 127 WCM247_Z9_1 Tissue 7 86415634 G A GRM3 p.A176T 0 910.335821 134 WCM247_Z9_1 Tissue 8 56015436 G T XKR4 p.V130F 0 1430.189781 137 WCM247_Z9_1 Tissue 8 56436599 G A XKR4 p.R589Q 0 750.164557 79 WCM247_Z9_1 Tissue 8 97978169 C G CPQ p.L286V 0 34 0.09901101 WCM247_Z9_1 Tissue 1 185894321 G T HMCN1 p.L476F 0 51 0.449275 69WCM252 Plasma 17 4851661 T C PFN1 p.N10S 0 50 0.368421 76 WCM252 Plasma17 62496142 G C DDX5 p.P582A 0 35 0.054054 74 WCM252 Plasma 2 231134273A C SP140 p.M423L 0 51 0.346535 101 WCM252 Plasma 5 61785151 G A IPO11p.M444I 0 45 0.474576 59 WCM252 Plasma 9 96859671 C T PTPDC1 p.R221W 045 0.421053 114 WCM252 Plasma 1 110768678 C T KCNC4 p.P566L 0 69 0.3 80WCM252_Z3_1 Tissue 11 56086504 G A OR8K3 p.G241E 0 46 0.088235 68WCM252_Z3_1 Tissue 11 6624716 T A RRP8 p.E6V 0 94 0.102362 127WCM252_Z3_1 Tissue 1 185894321 G T HMCN1 p.L476F 0 105 0.307692 52WCM252_Z3_1 Tissue 12 121712178 G A CAMKK2 p.S51F 0 77 0.121495 107WCM252_Z3_1 Tissue 12 124904531 C T NCOR2 p.R485Q 0 189 0.111607 224WCM252_Z3_1 Tissue 1 245019798 C T HNRNPU p.G625R 0 39 0.083333 48WCM252_Z3_1 Tissue 12 7842988 G A GDF3 p.P194L 0 64 0.052632 95WCM252_Z3_1 Tissue 13 20763512 G A GJB2 p.P70L 0 154 0.217617 193WCM252_Z3_1 Tissue 13 58207821 T A PCDH17 p.S381T 0 130 0.282353 85WCM252_Z3_1 Tissue 13 58207822 C A PCDH17 p.S381Y 0 129 0.282353 85WCM252_Z3_1 Tissue 14 91804910 C T CCDC88C p.D272N 0 101 0.107843 102WCM252_Z3_1 Tissue 15 39882019 G A THBS1 p.R647H 0 55 0.36 75WCM252_Z3_1 Tissue 15 43500848 T A EPB42 p.R320* 0 103 0.103093 97WCM252_Z3_1 Tissue 15 69553448 G A GLCE p.W203* 0 42 0.128205 39WCM252_Z3_1 Tissue 16 23079683 G T USP31 p.A1248D 0 76 0.060606 99WCM252_Z3_1 Tissue 16 30100319 G T TBX6 p.P189H 0 72 0.134146 82WCM252_Z3_1 Tissue 17 48639044 T A CACNA1G p.L75H 0 149 0.181818 143WCM252_Z3_1 Tissue 17 79477798 A T ACTG1 p.L349Q 0 71 0.055556 72WCM252_Z3_1 Tissue 17 80678231 G A FN3KRP p.G126D 0 164 0.233161 193WCM252_Z3_1 Tissue 1 978666 A G AGRN p.T478A 0 86 0.150538 93WCM252_Z3_1 Tissue 19 9087822 C A MUC16 p.K1331N 0 56 0.056818 88WCM252_Z3_1 Tissue 2 231134273 A C SP140 p.M423L 0 66 0.430556 72WCM252_Z3_1 Tissue 3 141884523 T A GK5 p.S511C 0 44 0.121212 66WCM252_Z3_1 Tissue 4 122103913 A T TNIP3 p.L43Q 0 106 0.052632 114WCM252_Z3_1 Tissue 4 17609154 G A LAP3 p.G501E 0 65 0.1875 48WCM252_Z3_1 Tissue 4 183676240 C A TENM3 p.P1574T 0 87 0.421875 64WCM252_Z3_1 Tissue 4 47605450 A T CORIN p.C926S 0 132 0.125 136WCM252_Z3_1 Tissue 6 167343198 C T RNASET2 p.G217R 0 218 0.17757 107WCM252_Z3_1 Tissue 8 122641438 A T HAS2 p.L48Q 0 133 0.130769 130WCM252_Z3_1 Tissue 8 144803964 C T MAPK15 p.Q458* 0 83 0.096774 62WCM252_Z3_1 Tissue 8 35584026 C T UNC5D p.R554C 0 154 0.316239 117WCM252_Z3_1 Tissue 9 123783877 C A C5 p.L404F 0 168 0.090909 187WCM252_Z3_1 Tissue 9 126783486 G A LHX2 p.R279Q 0 124 0.050562 178WCM252_Z3_1 Tissue 9 96859671 C T PTPDC1 p.R221W 0.007407 135 0.319672122 WCM252_Z3_1 Tissue X 8767075 C T FAM9A p.R51H 0 42 0.541667 48WCM252_Z3_1 Tissue X 96213115 G C DIAPH2 p.E635Q 0 35 0.21875 32WCM252_Z3_1 Tissue 11 118100616 G T MPZL3 p.T234K 0 64 0.083333 36WCM253_Z1_1 Tissue 11 14907394 G A CYP2R1 p.L99F 0 74 0.241379 87WCM253_Z1_1 Tissue 1 1153950 T C SDF4 p.E267G 0 226 0.259804 204WCM253_Z1_1 Tissue 1 12252505 G A TNFRSF1B p.V159M 0 528 0.183007 459WCM253_Z1_1 Tissue 1 151680357 G T CELF3 p.L181I 0 138 0.415385 195WCM253_Z1_1 Tissue 1 151687150 A G CELF3 p.C50R 0 44 0.258065 31WCM253_Z1_1 Tissue 1 155912410 C T RXFP4 p.L304F 0 75 0.085714 70WCM253_Z1_1 Tissue 1 158584086 C A SPTA1 p.G2267C 0 61 0.178571 56WCM253_Z1_1 Tissue 1 158615007 T A SPTA1 p.K1389* 0 108 0.132653 98WCM253_Z1_1 Tissue 11 58979775 C A MPEG1 p.R188S 0 79 0.089286 56WCM253_Z1_1 Tissue 1 160144484 A G ATP1A4 p.D753G 0 85 0.103093 97WCM253_Z1_1 Tissue 11 64535244 C T SF1 p.G381S 0 125 0.069767 86WCM253_Z1_1 Tissue 1 175360506 C G TNR p.K475N 0 84 0.227723 101WCM253_Z1_1 Tissue 1 186863272 G A PLA2G4A p.G103R 0 68 0.518182 110WCM253_Z1_1 Tissue 1 192153607 A G RGS18 p.N211D 0 67 0.275 80WCM253_Z1_1 Tissue 12 21015752 G C SLCO1B3 p.A231P 0 144 0.123188 138WCM253_Z1_1 Tissue 1 230493041 C T PGBD5 p.A51T 0 115 0.414894 94WCM253_Z1_1 Tissue 12 48387269 G C COL2A1 p.P314R 0 53 0.290909 55WCM253_Z1_1 Tissue 12 64505618 G A SRGAP1 p.V666I 0 69 0.188406 69WCM253_Z1_1 Tissue 1 27432553 G C SLC9A1 p.I436M 0 368 0.19863 292WCM253_Z1_1 Tissue 12 95926840 G A USP44 p.A398V 0 142 0.705479 146WCM253_Z1_1 Tissue 14 23103448 G T OR6J1 p.T90N 0 84 0.230769 78WCM253_Z1_1 Tissue 14 31872059 G C HEATR5A p.S41R 0 58 0.142857 56WCM253_Z1_1 Tissue 14 52520480 C T NID2 p.E416K 0 180 0.617647 238WCM253_Z1_1 Tissue 14 94404173 C T ASB2 p.E500K 0 50 0.311111 90WCM253_Z1_1 Tissue 15 37390178 C T MEIS2 p.A79T 0 92 0.103448 58WCM253_Z1_1 Tissue 16 22337107 C G POLR3E p.D458E 0 90 0.28125 64WCM253_Z1_1 Tissue 16 27689194 G A KIAA0556 p.D229N 0 87 0.157025 121WCM253_Z1_1 Tissue 16 27689230 G C KIAA0556 p.D241H 0 95 0.164062 128WCM253_Z1_1 Tissue 16 51174296 C T SALL1 p.E613K 0 98 0.089888 89WCM253_Z1_1 Tissue 1 67263810 C T INSL5 p.M98I 0 98 0.493671 79WCM253_Z1_1 Tissue 17 10535189 T G MYH3 p.K1701Q 0 84 0.648649 37WCM253_Z1_1 Tissue 17 15207287 T A TEKT3 p.Y480F 0 68 0.306667 75WCM253_Z1_1 Tissue 17 4720324 T C PLD2 p.F559L 0 49 0.432432 37WCM253_Z1_1 Tissue 17 47395002 C T ZNF652 p.R29H 0 91 0.083333 72WCM253_Z1_1 Tissue 18 10791250 C A PIEZO2 p.E611* 0 95 0.067568 74WCM253_Z1_1 Tissue 1 881862 C G NOC2L p.G575R 0 85 0.228571 35WCM253_Z1_1 Tissue 19 2403107 G A TMPRSS9 p.C161Y 0 196 0.266667 135WCM253_Z1_1 Tissue 19 2403108 C A TMPRSS9 p.C161* 0 196 0.268657 134WCM253_Z1_1 Tissue 19 36293972 C T PRODH2 p.R413H 0 138 0.427273 110WCM253_Z1_1 Tissue 19 8656706 C G ADAMTS10 p.R592P 0 128 0.108696 46WCM253_Z1_1 Tissue 20 40050229 A C CHD6 p.F1682L 0 115 0.152542 118WCM253_Z1_1 Tissue 21 47863774 C A PCNT p.P3251Q 0 71 0.070588 85WCM253_Z1_1 Tissue 2 201846030 G T FAM126B p.S519Y 0 111 0.162791 129WCM253_Z1_1 Tissue 2 239049727 C A KLHL30 p.A111E 0 53 0.079365 63WCM253_Z1_1 Tissue 2 32704553 G C BIRC6 p.A2426P 0 61 0.122807 57WCM253_Z1_1 Tissue 3 12953144 G C IQSEC1 p.L815V 0 133 0.166667 84WCM253_Z1_1 Tissue 3 167023464 G T ZBBX p.S564R 0 35 0.210526 38WCM253_Z1_1 Tissue 3 39230124 C A XIRP1 p.W271C 0 82 0.485294 68WCM253_Z1_1 Tissue 3 69058976 C T EOGT p.G8R 0 91 0.294118 34WCM253_Z1_1 Tissue 4 110222996 C A COL25A1 p.Q60H 0 217 0.27907 129WCM253_Z1_1 Tissue 4 126412490 C A FAT4 p.S4838Y 0 145 0.37931 58WCM253_Z1_1 Tissue 5 26915751 T A CDH9 p.E170D 0 42 0.106383 47WCM253_Z1_1 Tissue 5 5191866 G C ADAMTS16 p.G426R 0 162 0.109827 173WCM253_Z1_1 Tissue 6 28474114 T C GPX6 p.N112D 0 284 0.325243 206WCM253_Z1_1 Tissue 6 39046906 G T GLP1R p.V325F 0 166 0.19337 181WCM253_Z1_1 Tissue 6 75833695 C G COL12A1 p.E2280D 0 136 0.086207 58WCM253_Z1_1 Tissue 7 104758428 A C SRPK2 p.F653V 0 225 0.403292 243WCM253_Z1_1 Tissue 8 28385331 A T FZD3 p.I352F 0 174 0.521277 94WCM253_Z1_1 Tissue 8 41543767 G T ANK1 p.D1431E 0 220 0.438095 105WCM253_Z1_1 Tissue 9 34514691 C T DNAI1 p.A591V 0 117 0.355556 90WCM253_Z1_1 Tissue 10 120883013 A G FAM45A p.D209G 0 135 0.246753 77WCM261_Z4_1 Tissue 10 99473795 C A MARVELD1 p.Y54* 0 45 0.134615 52WCM261_Z4_1 Tissue 11 120099678 C T OAF p.R217C 0 137 0.303191 188WCM261_Z4_1 Tissue 11 62415862 C G INTS5 p.G564R 0 122 0.216 125WCM261_Z4_1 Tissue 11 6661065 C T DCHS1 p.G594R 0 277 0.158103 253WCM261_Z4_1 Tissue 12 108939078 T C SART3 p.Y189C 0 114 0.20339 118WCM261_Z4_1 Tissue 12 123738288 C A C12orf65 p.L23I 0 122 0.229885 87WCM261_Z4_1 Tissue 12 13243577 G A GSG1 p.P75L 0 75 0.173913 69WCM261_Z4_1 Tissue 12 22622651 G A C2CD5 p.P842L 0 66 0.340426 47WCM261_Z4_1 Tissue 1 223939730 G A CAPN2 p.E311K 0 81 0.328244 131WCM261_Z4_1 Tissue 12 5724394 T C ANO2 p.N630S 0 84 0.17094 117WCM261_Z4_1 Tissue 12 58006878 G T ARHGEF25 p.C88F 0 36 0.25 36WCM261_Z4_1 Tissue 14 105945464 G T CRIP2 p.E137* 0 74 0.15873 63WCM261_Z4_1 Tissue 14 94254001 C T PRIMA1 p.A22T 0 79 0.175 80WCM261_Z4_1 Tissue 1 55223781 T C PARS2 p.I352V 0 66 0.222222 54WCM261_Z4_1 Tissue 15 89857911 T A FANCI p.F1263L 0 155 0.156716 134WCM261_Z4_1 Tissue 15 89857912 C T FANCI p.L1264F 0 156 0.156716 134WCM261_Z4_1 Tissue 16 1995589 C T RPL3L p.V360M 0 171 0.24812 133WCM261_Z4_1 Tissue 16 816887 C T MSLN p.A467V 0 54 0.339286 56WCM261_Z4_1 Tissue 17 47696450 A C SPOP p.F125V 0 113 0.383562 73WCM261_Z4_1 Tissue 17 61790789 T A STRADA p.N109Y 0 101 0.157895 95WCM261_Z4_1 Tissue 17 79477798 A T ACTG1 p.L349Q 0 77 0.117647 68WCM261_Z4_1 Tissue 17 8198082 A G SLC25A35 p.V15A 0 70 0.225806 62WCM261_Z4_1 Tissue 19 49316453 G T HSD17B14 p.D264E 0 153 0.101695 177WCM261_Z4_1 Tissue 20 30720912 G A TM9SF4 p.D38N 0 50 0.074074 54WCM261_Z4_1 Tissue 2 182423323 C T CERKL p.A290T 0 35 0.414634 41WCM261_Z4_1 Tissue 2 88407999 G T SMYD1 p.A419S 0 123 0.189189 111WCM261_Z4_1 Tissue 3 155632310 C G GMPS p.T330S 0 81 0.064935 77WCM261_Z4_1 Tissue 3 170108053 A C SKIL p.E491A 0 63 0.515625 64WCM261_Z4_1 Tissue 3 38991699 G C SCN11A p.P52R 0 69 0.105263 57WCM261_Z4_1 Tissue 3 39374616 G A CCR8 p.S265N 0 81 0.156627 83WCM261_Z4_1 Tissue 3 44489502 G A ZNF445 p.S554L 0 95 0.290698 86WCM261_Z4_1 Tissue 4 57237798 T C AASDH p.D227G 0 60 0.096774 31WCM261_Z4_1 Tissue 6 152708456 C A SYNE1 p.E2746D 0 55 0.075 40WCM261_Z4_1 Tissue 6 24547442 C A KIAA0319 p.G1057V 0 47 0.297297 37WCM261_Z4_1 Tissue 6 41895258 A C BYSL p.K139Q 0 265 0.183746 283WCM261_Z4_1 Tissue 6 65327345 G T EYS p.P1217H 0 90 0.152174 92WCM261_Z4_1 Tissue 7 130364004 G A TSGA13 p.L126F 0 68 0.191176 68WCM261_Z4_1 Tissue 8 124749564 C T ANXA13 p.R4H 0 41 0.12766 47WCM261_Z4_1 Tissue 9 108147760 G C SLC44A1 p.D643H 0 52 0.157895 38WCM261_Z4_1 Tissue 9 4793179 G A RCL1 p.V30I 0 63 0.26 50 WCM261_Z4_1Tissue 9 5906943 G A MLANA p.G78E 0 56 0.356164 73 WCM261_Z4_1 Tissue 973230925 G C TRPM3 p.P797A 0 148 0.210084 119 WCM261_Z4_1 Tissue 995077237 C T NOL8 p.G557D 0 111 0.149425 87 WCM261_Z4_1 Tissue X152821522 C T ATP2B3 p.R692* 0 145 0.535088 114 WCM261_Z4_1 Tissue X2772191 C T GYG2 p.T138I 0 118 0.405063 79 WCM261_Z4_1 Tissue 1064219525 G A ZNF365 p.R317H 0 107 0.123596 89 WCM2_Z3_1 Tissue 1157518560 C T BTBD18 p.C34Y 0 112 0.213592 103 WCM2_Z3_1 Tissue 1167925529 G C SUV420H1 p.L762V 0 54 0.333333 33 WCM2_Z3_1 Tissue 1256365029 T C CDK2 p.S264P 0 139 0.228395 162 WCM2_Z3_1 Tissue 1257598451 A C LRP1 p.N3705H 0 302 0.301887 212 WCM2_Z3_1 Tissue 13114507910 A G TMEM255B p.Y241C 0 53 0.304348 46 WCM2_Z3_1 Tissue 136886153 C T OSCP1 p.G305R 0 186 0.163121 141 WCM2_Z3_1 Tissue 14105246526 C A AKT1 p.R25L 0 126 0.155844 77 WCM2_Z3_1 Tissue 15 77236202A C RCN2 p.D184A 0 60 0.25 32 WCM2_Z3_1 Tissue 15 90193016 G C KIF7p.A162G 0 55 0.121951 41 WCM2_Z3_1 Tissue 1 6659260 T C KLHL21 p.Y425C 068 0.122807 57 WCM2_Z3_1 Tissue 16 706421 G T WDR90 p.A696S 0 550.144578 83 WCM2_Z3_1 Tissue 16 72107856 A G HPR p.N24S 0 230 0.216783143 WCM2_Z3_1 Tissue 19 34857731 A G GPI p.N86S 0 59 0.147541 61WCM2_Z3_1 Tissue 1 94520757 C A ABCA4 p.E833* 0 48 0.294118 34 WCM2_Z3_1Tissue 19 45322365 G T BCAM p.W463C 0 213 0.485714 70 WCM2_Z3_1 Tissue20 32212668 T G CBFA2T2 p.L273R 0 218 0.343042 309 WCM2_Z3_1 Tissue 2057769643 G A ZNF831 p.R1190H 0 48 0.5 56 WCM2_Z3_1 Tissue 20 62164907 GA PTK6 p.R223* 0 119 0.25 112 WCM2_Z3_1 Tissue 2 15601386 G C NBASp.L760V 0 79 0.096774 62 WCM2_Z3_1 Tissue 2 220078380 G C ABCB6 p.D529E0 293 0.141414 297 WCM2_Z3_1 Tissue 2 228883310 A T SPHKAP p.S754T 0 470.1875 32 WCM2_Z3_1 Tissue 3 170244539 C T SLC7A14 p.V63I 0 47 0.34545555 WCM2_Z3_1 Tissue 3 35729235 C T ARPP21 p.S89L 0 139 0.189394 132WCM2_Z3_1 Tissue 3 49063981 T C IMPDH2 p.Y294C 0 106 0.170543 129WCM2_Z3_1 Tissue 3 50677812 C T MAPKAPK3 p.P79S 0 97 0.307018 114WCM2_Z3_1 Tissue 4 71554892 G C UTP3 p.Q166H 0 144 0.25 136 WCM2_Z3_1Tissue 5 149782709 T G CD74 p.R264S 0 83 0.064516 62 WCM2_Z3_1 Tissue 537121743 C A C5orf42 p.C3000F 0 44 0.441176 34 WCM2_Z3_1 Tissue 6116833031 C G FAM26E p.P58A 0 76 0.211538 104 WCM2_Z3_1 Tissue 7122342633 C G RNF148 p.E58Q 0 65 0.181818 66 WCM2_Z3_1 Tissue 7 53103860G A POM121L12 p.A166T 0 83 0.235849 106 WCM2_Z3_1 Tissue 7 5414109 G ATNRC18 p.R936W 0 238 0.263359 262 WCM2_Z3_1 Tissue 8 29989567 C G MBOAT4p.R400S 0 341 0.215385 325 WCM2_Z3_1 Tissue 9 94495697 G A ROR2 p.T215M0 156 0.378151 119 WCM2_Z3_1 Tissue X 118140114 C A LONRF3 p.C482* 0 430.387097 31 WCM2_Z3_1 Tissue 10 64936214 A C JMJD1C p.L2415R 0 610.316239 117 WCM341 Plasma 10 89624301 G C PTEN p.L25F 0 33 0.25 44WCM341 Plasma 1 163042226 A C RGS4 p.K29T 0 59 0.066038 106 WCM341Plasma 1 203194906 G T CHIT1 p.L50I 0 43 0.05102 98 WCM341 Plasma 1204103659 C T ETNK2 p.D358N 0 35 0.052632 95 WCM341 Plasma 12 22610051 GA C2CD5 p.R860W 0 69 0.252252 111 WCM341 Plasma 1 24409176 T C MYOM3p.K667E 0 44 0.218391 87 WCM341 Plasma 14 23893217 G A MYH7 p.R941C 0 390.201835 109 WCM341 Plasma 14 94754861 C T SERPINA10 p.E252K 0 400.325301 83 WCM341 Plasma 17 48917416 G A WFIKKN2 p.R256Q 0 53 0.37179578 WCM341 Plasma 19 15794478 C T CYP4F12 p.R275C 0 47 0.195402 87 WCM341Plasma 19 39660270 A G PAK4 p.D26G 0 59 0.081395 86 WCM341 Plasma 1942738770 G A GSK3A p.R243C 0 34 0.277778 54 WCM341 Plasma 19 49387247 CA TULP2 p.R373L 0 48 0.066038 106 WCM341 Plasma 19 50750329 C T MYH14p.R419C 0 38 0.080808 99 WCM341 Plasma 20 43753013 C T WFDC12 p.E26K 035 0.411765 85 WCM341 Plasma 2 100900812 C T LONRF2 p.R738H 0 340.136986 73 WCM341 Plasma 2 153526876 C T PRPF40A p.R500Q 0 53 0.08433783 WCM341 Plasma 2 1677426 A C PXDN p.F336C 0 39 0.318182 88 WCM341Plasma 2 192863795 G A TMEFF2 p.R226* 0 61 0.095238 84 WCM341 Plasma 2216259383 C A FN1 p.E1222* 0 75 0.052632 114 WCM341 Plasma 22 42992268 CT POLDIP3 p.R246Q 0 48 0.188034 117 WCM341 Plasma 2 37468845 G A NDUFAF7p.R178Q 0 77 0.359375 128 WCM341 Plasma 3 52430694 C T DNAH1 p.R3831C 032 0.065789 76 WCM341 Plasma 4 1341974 G A UVSSA p.C32Y 0 44 0.089286 56WCM341 Plasma 4 46314718 C T GABRA2 p.V91I 0 80 0.189189 111 WCM341Plasma 5 9337840 A C SEMA5A p.L70R 0 39 0.283582 67 WCM341 Plasma 6157150520 G A ARID1B p.G568R 0 40 0.422222 90 WCM341 Plasma 6 159653153T C FNDC1 p.S537P 0 43 0.443038 79 WCM341 Plasma 7 141952420 C T PRSS58p.D150N 0 57 0.072072 111 WCM341 Plasma 8 28420374 G A FZD3 p.R616Q 0 410.384615 104 WCM341 Plasma 9 32436385 C T ACO1 p.S746F 0 43 0.051546 97WCM341 Plasma 9 80336342 G A GNAQ p.S326F 0 41 0.087379 103 WCM341Plasma 11 2798256 G A KCNQ1 p.V576I 0 213 0.061818 275 WCM341_X1_1_p2Tissue 11 66837995 C T RHOD p.R144* 0 54 0.08 75 WCM341_X1_1_p2 Tissue12 22610051 G A C2CD5 p.R860W 0 151 0.091892 185 WCM341_X1_1_p2 Tissue 124409176 T C MYOM3 p.K667E 0 176 0.081545 233 WCM341_X1_1_p2 Tissue 1256398237 A G SUOX p.Q355R 0 66 0.235294 68 WCM341_X1_1_p2 Tissue 1326144947 G A ATP8A2 p.V506M 0.009174 109 0.181818 99 WCM341_X1_1_p2Tissue 1 34498248 C T CSMD2 p.R155H 0 63 0.196721 61 WCM341_X1_1_p2Tissue 13 61986379 G A PCDH20 p.P618L 0 50 0.140845 71 WCM341_X1_1_p2Tissue 14 58831848 A C ARID4A p.D1014A 0 95 0.054795 146 WCM341_X1_1_p2Tissue 14 94754861 C T SERPINA10 p.E252K 0.004032 248 0.231788 151WCM341_X1_1_p2 Tissue 15 33954809 C T RYR3 p.T1693M 0 99 0.189189 74WCM341_X1_1_p2 Tissue 17 37331720 C T CACNB1 p.R508Q 0 122 0.193548 124WCM341_X1_1_p2 Tissue 17 48917416 G A WFIKKN2 p.R256Q 0 104 0.2 80WCM341_X1_1_p2 Tissue 19 15794478 C T CYP4F12 p.R275C 0 82 0.152542 59WCM341_X1_1_p2 Tissue 19 39660270 A G PAK4 p.D26G 0 51 0.087719 57WCM341_X1_1_p2 Tissue 19 42738770 G A GSK3A p.R243C 0 168 0.144144 111WCM341_X1_1_p2 Tissue 19 47151848 G A DACT3 p.A594V 0 32 0.081633 49WCM341_X1_1_p2 Tissue 19 56466262 C T NLRP8 p.Q280* 0 120 0.107692 130WCM341_X1_1_p2 Tissue 20 18297333 G A ZNF133 p.R613Q 0 102 0.085714 70WCM341_X1_1_p2 Tissue 20 31023042 G T ASXL1 p.V843L 0 198 0.219178 219WCM341_X1_1_p2 Tissue 20 57415343 G A GNAS p.R61H 0 114 0.128205 117WCM341_X1_1_p2 Tissue 2 1677426 A C PXDN p.F336C 0 104 0.296296 54WCM341_X1_1_p2 Tissue 22 42992268 C T POLDIP3 p.R246Q 0 153 0.117647 136WCM341_X1_1_p2 Tissue 2 37468845 G A NDUFAF7 p.R178Q 0 116 0.173913 69WCM341_X1_1_p2 Tissue 3 147113965 C T ZIC4 p.R121H 0 181 0.101351 148WCM341_X1_1_p2 Tissue 5 140783253 G A PCDHGA9 p.R245Q 0 80 0.058824 85WCM341_X1_1_p2 Tissue 5 176562856 C T NSD1 p.A251V 0 36 0.073171 41WCM341_X1_1_p2 Tissue 6 157150520 G A ARID1B p.G568R 0 204 0.256098 164WCM341_X1_1_p2 Tissue 8 1497134 C T DLGAP2 p.T92M 0 86 0.070175 114WCM341_X1_1_p2 Tissue 8 28420374 G A FZD3 p.R616Q 0 46 0.3125 32WCM341_X1_1_p2 Tissue 9 32436385 C T ACO1 p.S746F 0 39 0.078947 38WCM341_X1_1_p2 Tissue 1 152883120 C A IVL p.L283M 0 46 0.122449 49WCM341_Z2_1 Tissue 12 22610051 G A C2CD5 p.R860W 0 151 0.264901 151WCM341_Z2_1 Tissue 12 54367092 G A HOXC11 p.G23S 0 101 0.132653 98WCM341_Z2_1 Tissue 12 56398237 A G SUOX p.Q355R 0 66 0.364583 96WCM341_Z2_1 Tissue 13 26144947 G A ATP8A2 p.V506M 0.009174 109 0.50549591 WCM341_Z2_1 Tissue 1 34498248 C T CSMD2 p.R155H 0 63 0.394366 71WCM341_Z2_1 Tissue 13 61986379 G A PCDH20 p.P618L 0 50 0.239437 71WCM341_Z2_1 Tissue 1 44415377 G A IPO13 p.V125M 0 106 0.116883 77WCM341_Z2_1 Tissue 14 58831848 A C ARID4A p.D1014A 0 95 0.062937 143WCM341_Z2_1 Tissue 14 94754861 C T SERPINA10 p.E252K 0.004032 2480.358621 145 WCM341_Z2_1 Tissue 15 33954809 C T RYR3 p.T1693M 0 990.221429 140 WCM341_Z2_1 Tissue 17 37331720 C T CACNB1 p.R508Q 0 1220.42 100 WCM341_Z2_1 Tissue 17 48917416 G A WFIKKN2 p.R256Q 0 1040.304348 69 WCM341_Z2_1 Tissue 17 80136396 G A CCDC57 p.A487V 0 1110.140625 64 WCM341_Z2_1 Tissue 19 39660270 A G PAK4 p.D26G 0 51 0.0561889 WCM341_Z2_1 Tissue 19 42738770 G A GSK3A p.R243C 0 168 0.395349 86WCM341_Z2_1 Tissue 19 50750329 C T MYH14 p.R419C 0 143 0.104167 96WCM341_Z2_1 Tissue 19 56466262 C T NLRP8 p.Q280* 0 120 0.142292 253WCM341_Z2_1 Tissue 20 31023042 G T ASXL1 p.V843L 0 198 0.318182 176WCM341_Z2_1 Tissue 20 43753013 C T WFDC12 p.E26K 0 82 0.505618 89WCM341_Z2_1 Tissue 20 57415343 G A GNAS p.R61H 0 114 0.151351 185WCM341_Z2_1 Tissue 2 100900812 C T LONRF2 p.R738H 0 37 0.177778 45WCM341_Z2_1 Tissue 2 153526876 C T PRPF40A p.R500Q 0 112 0.141026 78WCM341_Z2_1 Tissue 2 1677426 A C PXDN p.F336C 0 104 0.423729 59WCM341_Z2_1 Tissue 2 179732764 C T CCDC141 p.V855M 0 42 0.4 55WCM341_Z2_1 Tissue 22 21107282 G A PI4KA p.R908W 0 91 0.064103 78WCM341_Z2_1 Tissue 22 42992268 C T POLDIP3 p.R246Q 0 153 0.2375 160WCM341_Z2_1 Tissue 2 33752258 C T RASGRP3 p.R288C 0 76 0.126214 103WCM341_Z2_1 Tissue 2 37468845 G A NDUFAF7 p.R178Q 0 116 0.442857 70WCM341_Z2_1 Tissue 2 96962311 C T SNRNP200 p.R545H 0 77 0.072727 55WCM341_Z2_1 Tissue 3 147113965 C T ZIC4 p.R121H 0 181 0.155738 122WCM341_Z2_1 Tissue 5 109974035 G A TMEM232 p.A122V 0 58 0.066667 45WCM341_Z2_1 Tissue 5 140783253 G A PCDHGA9 p.R245Q 0 80 0.145833 48WCM341_Z2_1 Tissue 5 176562856 C T NSD1 p.A251V 0 36 0.090909 33WCM341_Z2_1 Tissue 6 157150520 G A ARID1B p.G568R 0 204 0.351145 131WCM341_Z2_1 Tissue 6 52616491 C T GSTA2 p.G144R 0 75 0.117647 102WCM341_Z2_1 Tissue 8 144946671 C T EPPK1 p.G251S 0 35 0.093023 43WCM341_Z2_1 Tissue 9 32436385 C T ACO1 p.S746F 0 39 0.075 40 WCM341_Z2_1Tissue 11 68191056 G A LRP5 p.E1043K 0 59 0.073171 123 WCM365 Plasma 1195826086 G A MAML2 p.P370L 0 39 0.396825 63 WCM365 Plasma 12 117962698 CA KSR2 p.M726I 0 49 0.231707 82 WCM365 Plasma 14 45696920 A T MIS18BP1p.D564E 0 72 0.081633 98 WCM365 Plasma 15 65684663 G T IGDCC4 p.S644Y 031 0.285714 42 WCM365 Plasma 16 27506176 T A GTF3C1 p.R896W 0 340.342857 70 WCM365 Plasma 17 1028687 G A ABR p.T26M 0 118 0.395161 124WCM365 Plasma 17 39551769 T A KRT31 p.Y232F 0 45 0.089744 78 WCM365Plasma 17 44249055 G C KANSL1 p.A152G 0 60 0.084507 71 WCM365 Plasma 2117135247 C T USP25 p.T28M 0 73 0.284091 88 WCM365 Plasma 2 218954730 C TRUFY4 p.R557C 0 36 0.057143 70 WCM365 Plasma 2 219563523 G A STK36p.A1086T 0 39 0.107143 56 WCM365 Plasma 2 26437359 G A HADHA p.R291* 059 0.06 100 WCM365 Plasma 3 127325123 A G MCM2 p.N279S 0 52 0.079365 63WCM365 Plasma 3 164750342 G C SI p.H902D 0 72 0.060606 99 WCM365 Plasma3 17053266 A T PLCL2 p.I684F 0 51 0.094595 74 WCM365 Plasma 4 113303691G C ALPK1 p.G87R 0 61 0.163043 92 WCM365 Plasma 5 110075047 C T SLC25A46p.P76L 0 72 0.285714 49 WCM365 Plasma 5 133311588 G A VDAC1 p.Q226* 0 440.259259 54 WCM365 Plasma 5 224505 G C SDHA p.E61Q 0 46 0.050633 79WCM365 Plasma 6 118790366 T A CEP85L p.D708V 0 50 0.118421 76 WCM365Plasma 6 123126094 C A SMPDL3A p.S260Y 0 66 0.066667 90 WCM365 Plasma 718705935 G A HDAC9 p.A520T 0 34 0.288889 45 WCM365 Plasma 9 100124651 AG CCDC180 p.K1255R 0 34 0.40625 64 WCM365 Plasma 9 32492500 T A DDX58p.K154* 0 76 0.516129 155 WCM365 Plasma 9 90500073 C A SPATA31E1 p.P224Q0 36 0.196429 56 WCM365 Plasma X 48211539 G T SSX3 p.P109Q 0 1140.119497 159 WCM365 Plasma X 70444128 A G GJB1 p.T191A 0 39 0.086957 69WCM365 Plasma 10 48370665 T A ZNF488 p.C45S 0 186 0.096257 187WCM365_Z2_1 Tissue 11 120996471 G T TECTA p.C555F 0 103 0.131868 91WCM365_Z2_1 Tissue 11 18231471 G A RP11- p.R86Q 0.009259 216 0.37963 216WCM365_Z2_1 Tissue 113D6.10 11 1858448 G T SYT8 p.W331C 0 221 0.173203306 WCM365_Z2_1 Tissue 11 56000214 C A OR5T2 p.E150* 0 142 0.167832 143WCM365_Z2_1 Tissue 11 95826086 G A MAML2 p.P370L 0 201 0.395745 235WCM365_Z2_1 Tissue 12 133237686 C T POLE p.G977R 0 105 0.089109 101WCM365_Z2_1 Tissue 1 39352229 C A RHBDL2 p.A287S 0 76 0.115385 52WCM365_Z2_1 Tissue 1 43739015 C T TMEM125 p.R208C 0 263 0.489362 188WCM365_Z2_1 Tissue 15 35212564 G C AQR p.T397S 0 55 0.264706 34WCM365_Z2_1 Tissue 16 27506176 T A GTF3C1 p.R896W 0 88 0.464912 114WCM365_Z2_1 Tissue 17 1028687 G A ABR p.T26M 0 267 0.328084 381WCM365_Z2_1 Tissue 17 43893886 C T CRHR1 p.A60V 0 122 0.111111 72WCM365_Z2_1 Tissue 1 75037769 G A C1orf173 p.R1209C 0 321 0.424419 172WCM365_Z2_1 Tissue 17 7578403 C A TP53 p.C176F 0 171 0.410256 117WCM365_Z2_1 Tissue 18 43481106 G C EPG5 p.R1501G 0 51 0.189189 37WCM365_Z2_1 Tissue 19 18280021 G T PIK3R2 p.V702L 0 86 0.375 80WCM365_Z2_1 Tissue 19 3543842 G A C19orf71 p.R155Q 0 119 0.058824 85WCM365_Z2_1 Tissue 19 9057411 G T MUC16 p.S10012Y 0 79 0.094828 116WCM365_Z2_1 Tissue 19 9362223 T A OR7E24 p.F168L 0 74 0.166667 132WCM365_Z2_1 Tissue 22 20229347 C T RTN4R p.G437R 0 49 0.15 40WCM365_Z2_1 Tissue 2 227896939 C T COL4A4 p.E1211K 0 189 0.243523 193WCM365_Z2_1 Tissue 2 231313828 C A SP100 p.S183R 0 51 0.057692 52WCM365_Z2_1 Tissue 2 97217824 G C ARID5A p.G520A 0 88 0.165605 157WCM365_Z2_1 Tissue 3 38017293 G A CTDSPL p.V205M 0 189 0.209677 124WCM365_Z2_1 Tissue 4 113303691 G C ALPK1 p.G87R 0 145 0.230769 104WCM365_Z2_1 Tissue 4 47548757 C A ATP10D p.H505N 0 299 0.167164 335WCM365_Z2_1 Tissue 5 110075047 C T SLC25A46 p.P76L 0 80 0.365854 41WCM365_Z2_1 Tissue 5 172518005 G T CREBRF p.E275* 0 134 0.064516 186WCM365_Z2_1 Tissue 5 83356276 G T EDIL3 p.S327* 0 82 0.097561 82WCM365_Z2_1 Tissue 7 100240883 G A ACTL6B p.R423* 0 73 0.214286 98WCM365_Z2_1 Tissue 7 155755684 C A AC021218.2 p.T54K 0 122 0.113821 123WCM365_Z2_1 Tissue 7 77975264 C A MAGI2 p.K400N 0 98 0.084112 107WCM365_Z2_1 Tissue 8 110655004 C A SYBU p.S61I 0 69 0.106557 122WCM365_Z2_1 Tissue 8 140630515 G A KCNK9 p.R371W 0 63 0.073034 178WCM365_Z2_1 Tissue 8 52321348 G A PXDNL p.R946* 0 79 0.565217 69WCM365_Z2_1 Tissue 9 100124651 A G CCDC180 p.K1255R 0 82 0.464286 84WCM365_Z2_1 Tissue 9 32492500 T A DDX58 p.K154* 0 49 0.696078 102WCM365_Z2_1 Tissue X 106028343 C T RNF128 p.R261C 0 60 0.258065 62WCM365_Z2_1 Tissue X 48211539 G T SSX3 p.P109Q 0 90 0.134185 313WCM365_Z2_1 Tissue 12 51740409 T G CELA1 p.Y5S 0 33 0.175 40 WCM366Plasma 12 51740410 A G CELA1 p.Y5H 0 34 0.170732 41 WCM366 Plasma 1543712787 T C TP53BP1 p.D1461G 0 33 0.121951 41 WCM366 Plasma 19 36297954G A PRODH2 p.R299W 0 88 0.052632 95 WCM366 Plasma 8 100568874 G A VPS13Bp.A1673T 0 37 0.071429 42 WCM366 Plasma X 118544323 C T SLC25A43 p.Q230*0 38 0.071429 42 WCM366 Plasma 1 152059178 A G TCHHL1 p.V327A 0 940.391892 74 WCM366_X1_1 Tissue 11 5878161 T C OR52E8 p.T258A 0 520.306452 62 WCM366_X1_1 Tissue 11 93431553 C G KIAA1731 p.Q1159E 0 420.40678 59 WCM366_X1_1 Tissue 12 122260845 C T SETD1B p.R1454* 0 1450.463415 82 WCM366_X1_1 Tissue 14 70926292 G C ADAM21 p.L692F 0 500.521739 46 WCM366_X1_1 Tissue 16 1961776 C T HS3ST6 p.A282T 0 1630.373134 134 WCM366_X1_1 Tissue 16 56792499 C T NUP93 p.R77* 0 840.361702 94 WCM366_X1_1 Tissue 20 2686344 C T EBF4 p.R87C 0 76 0.08333372 WCM366_X1_1 Tissue 21 34877955 G C GART p.L880V 0 80 0.481481 54WCM366_X1_1 Tissue 4 169196534 C T DDX60 p.D756N 0 85 0.247525 101WCM366_X1_1 Tissue 5 1219159 G A SLC6A19 p.V439I 0 159 0.139344 122WCM366_X1_1 Tissue 8 113564857 A T CSMD3 p.W1443R 0 39 0.162162 37WCM366_X1_1 Tissue 8 92982906 G T RUNX1T1 p.Q507K 0 31 0.138889 36WCM366_X1_1 Tissue 9 27056345 A G IFT74 p.E504G 0 37 0.328125 64WCM366_X1_1 Tissue 9 35675544 A G CA9 p.Q138R 0 69 0.3 70 WCM366_X1_1Tissue 11 63258442 A G HRASLS5 p.L22P 0 37 0.052632 38 WCM369 Plasma 1543712787 T C TP53BP1 p.D1461G 0 32 0.090909 44 WCM369 Plasma 2 85554616G C TGOLN2 p.T80S 0 37 0.053571 56 WCM369 Plasma 11 57563960 G A CTNND1p.R151Q 0 43 0.090909 33 WCM369_Z2_1 Tissue 1 209785486 G A CAMK1Gp.C422Y 0 109 0.164384 73 WCM369_Z2_1 Tissue 1 244217801 C T ZBTB18p.S242L 0 54 0.069767 43 WCM369_Z2_1 Tissue 14 20823096 C T PARP2p.H311Y 0 247 0.079245 265 WCM369_Z2_1 Tissue 14 79746833 G C NRXN3p.V67L 0 122 0.17 100 WCM369_Z2_1 Tissue 15 42361122 C T PLA2G4D p.A750T0 68 0.103896 77 WCM369_Z2_1 Tissue 16 78458901 T A WWOX p.L247* 0 1710.148936 141 WCM369_Z2_1 Tissue 17 37263686 C T PLXDC1 p.G229S 0 1200.146341 123 WCM369_Z2_1 Tissue 17 8349120 C A NDEL1 p.Q60K 0 122 0.07580 WCM369_Z2_1 Tissue 19 50434121 C T ATF5 p.A5V 0 81 0.133333 90WCM369_Z2_1 Tissue 2 153488619 A T FMNL2 p.N258I 0 145 0.126667 150WCM369_Z2_1 Tissue 3 130159551 C A COL6A5 p.D2123E 0 39 0.166667 36WCM369_Z2_1 Tissue 6 31596004 G A PRRC2A p.E585K 0 85 0.070796 113WCM369_Z2_1 Tissue 7 27239668 C A HOXA13 p.R10L 0 71 0.090909 66WCM369_Z2_1 Tissue X 107381043 G A ATG4A p.C186Y 0 36 0.194444 36WCM369_Z2_1 Tissue 10 124189222 C G PLEKHA1 p.S328C 0 33 0.078125 64WCM4 Plasma 10 5247768 G A AKR1C4 p.D140N 0 46 0.055556 72 WCM4 Plasma10 64148158 A T ZNF365 p.E249D 0 38 0.185185 54 WCM4 Plasma 11 22384296G A SLC17A6 p.G225R 0 41 0.058824 85 WCM4 Plasma 1 155152269 C T TRIM46p.R483W 0 39 0.175 80 WCM4 Plasma 1 181685206 G A CACNA1E p.R419Q 0 320.135135 74 WCM4 Plasma 14 47120402 C T RPL10L p.E180K 0 41 0.117647 68WCM4 Plasma 14 64606669 G T SYNE2 p.D4952Y 0 53 0.144928 69 WCM4 Plasma15 43769897 C A TP53BP1 p.Q278H 0 42 0.050633 79 WCM4 Plasma 16 28878668T C SH2B1 p.L319P 0 37 0.119403 67 WCM4 Plasma 17 10355643 C A MYH4p.R1118L 0 34 0.204545 44 WCM4 Plasma 19 43411209 C G PSG6 p.G369R 0 640.090909 88 WCM4 Plasma 2 187703894 C A ZSWIM2 p.A96S 0 46 0.063291 79WCM4 Plasma 2 24103566 T C ATAD2B p.R282G 0 46 0.183099 71 WCM4 Plasma 227322070 G T KHK p.V191F 0 36 0.068182 44 WCM4 Plasma 3 138256090 G ACEP70 p.R189C 0 39 0.107692 65 WCM4 Plasma 3 29910367 T A RBMS3 p.L219Q0 37 0.107692 65 WCM4 Plasma 3 42794072 G A CCDC13 p.R170W 0 34 0.1 80WCM4 Plasma 7 27872537 C T JAZF1 p.R205H 0 48 0.054054 74 WCM4 Plasma 787175277 C T ABCB1 p.V597I 0 33 0.112676 71 WCM4 Plasma 8 93029459 G CRUNX1T1 p.T74R 0 51 0.052632 76 WCM4 Plasma 9 21409485 C A IFNA8 p.L104I0 37 0.068966 87 WCM4 Plasma 9 4697857 G A CDC37L1 p.R242H 0 62 0.12345781 WCM4 Plasma 10 124189222 C G PLEKHA1 p.S328C 0 55 0.101695 59WCM4_X1_1 Tissue 10 27048040 A C ABI1 p.F343L 0 70 0.075 80 WCM4_X1_1Tissue 10 49447674 G C FRMPD2 p.H254Q 0 213 0.088106 227 WCM4_X1_1Tissue 10 5247768 G A AKR1C4 p.D140N 0 106 0.215054 93 WCM4_X1_1 Tissue10 64148158 A T ZNF365 p.E249D 0 124 0.229358 109 WCM4_X1_1 Tissue 1085984369 A T LRIT2 p.C204* 0 68 0.164706 85 WCM4_X1_1 Tissue 1 11097836T C MASP2 p.N308D 0 132 0.27451 102 WCM4_X1_1 Tissue 11 114441964 A CNXPE4 p.I444S 0 126 0.157143 140 WCM4_X1_1 Tissue 11 120831649 T C GRIK4p.Y636H 0 126 0.080537 149 WCM4_X1_1 Tissue 11 20077385 T A NAV2p.N1594K 0 144 0.055556 90 WCM4_X1_1 Tissue 1 150525561 C G ADAMTSL4p.P89R 0 36 0.130435 46 WCM4_X1_1 Tissue 1 155057737 A T EFNA3 p.N100I 0115 0.096 125 WCM4_X1_1 Tissue 1 155152269 C T TRIM46 p.R483W 0 310.333333 39 WCM4_X1_1 Tissue 1 156756703 G A PRCC p.E274K 0 56 0.13114861 WCM4_X1_1 Tissue 1 181685206 G A CACNA1E p.R419Q 0 60 0.349398 83WCM4_X1_1 Tissue 1 20639400 G A VWA5B1 p.V71M 0 188 0.113095 168WCM4_X1_1 Tissue 1 228556463 T A OBSCN p.I6603N 0 229 0.069204 289WCM4_X1_1 Tissue 12 53580203 T G ZNF740 p.C134W 0 121 0.096491 114WCM4_X1_1 Tissue 13 61985648 C A PCDH20 p.E862* 0 41 0.177778 45WCM4_X1_1 Tissue 13 77730258 G A MYCBP2 p.P2246S 0 90 0.065574 61WCM4_X1_1 Tissue 14 21862459 C T CHD8 p.R1859H 0 151 0.105263 133WCM4_X1_1 Tissue 14 47120402 C T RPL10L p.E180K 0 50 0.162791 43WCM4_X1_1 Tissue 14 77576197 C G KIAA1737 p.S60C 0 63 0.112903 62WCM4_X1_1 Tissue 15 48757768 C G FBN1 p.D1647H 0 99 0.090909 88WCM4_X1_1 Tissue 15 83718831 C T BTBD1 p.D220N 0 40 0.088235 34WCM4_X1_1 Tissue 15 95001413 T A MCTP2 p.D766E 0 66 0.095238 42WCM4_X1_1 Tissue 16 2026856 C A TBL3 p.T445N 0 88 0.095238 105 WCM4_X1_1Tissue 16 24831573 C T TNRC6A p.R1732C 0 68 0.078947 38 WCM4_X1_1 Tissue16 28878668 T C SH2B1 p.L319P 0 46 0.116279 43 WCM4_X1_1 Tissue 1630079982 G A ALDOA p.V114I 0 60 0.175824 91 WCM4_X1_1 Tissue 16 3108217C A MMP25 p.L348M 0 111 0.082569 109 WCM4_X1_1 Tissue 16 3406560 C AOR2C1 p.T207N 0 185 0.190184 163 WCM4_X1_1 Tissue 16 55899940 C T CES5Ap.G214S 0 37 0.227273 44 WCM4_X1_1 Tissue 16 57758653 G A CCDC135p.R555H 0 198 0.211765 170 WCM4_X1_1 Tissue 17 36492868 C T GPR179p.R407Q 0 50 0.192308 52 WCM4_X1_1 Tissue 17 36517603 G C SOCS7 p.K266N0 48 0.06383 47 WCM4_X1_1 Tissue 18 28711744 C A DSC1 p.G767V 0 1090.051546 97 WCM4_X1_1 Tissue 18 2891006 T G EMILIN2 p.L294R 0 77 0.062564 WCM4_X1_1 Tissue 1 91177999 G A BARHL2 p.P345L 0 83 0.108108 74WCM4_X1_1 Tissue 19 15083650 G A SLC1A6 p.R25W 0 60 0.2 60 WCM4_X1_1Tissue 19 15990654 C T CYP4F2 p.R390Q 0 127 0.237624 101 WCM4_X1_1Tissue 19 39760242 A T IFNL2 p.T129S 0 194 0.235294 204 WCM4_X1_1 Tissue19 42873052 A G MEGF8 p.D2180G 0 224 0.117647 221 WCM4_X1_1 Tissue 1943411209 C G PSG6 p.G369R 0 63 0.176471 51 WCM4_X1_1 Tissue 20 60897408C T LAMA5 p.C2088Y 0 56 0.470588 68 WCM4_X1_1 Tissue 2 179462516 A G TTNp.V17457A 0 148 0.050847 118 WCM4_X1_1 Tissue 2 17955554 A C GEN1p.K363T 0 78 0.121951 41 WCM4_X1_1 Tissue 2 187703894 C A ZSWIM2 p.A96S0 75 0.148936 47 WCM4_X1_1 Tissue 22 24509535 C T CABIN1 p.R1374* 0 1080.230769 91 WCM4_X1_1 Tissue 2 24103566 T C ATAD2B p.R282G 0 67 0.35555645 WCM4_X1_1 Tissue 3 125855680 A T ALDH1L1 p.L424H 0 62 0.068493 73WCM4_X1_1 Tissue 3 138256090 G A CEP70 p.R189C 0 158 0.106977 215WCM4_X1_1 Tissue 3 156867735 T C CCNL1 p.E304G 0 46 0.3 60 WCM4_X1_1Tissue 3 173997355 G A NLGN1 p.E522K 0 147 0.068783 189 WCM4_X1_1 Tissue3 183907668 A G ABCF3 p.N447S 0 127 0.364055 217 WCM4_X1_1 Tissue 329910367 T A RBMS3 p.L219Q 0 84 0.092105 76 WCM4_X1_1 Tissue 3 49050727G A WDR6 p.R587H 0 164 0.052632 152 WCM4_X1_1 Tissue 4 17660050 C TFAM184B p.A654T 0.00641 156 0.270833 144 WCM4_X1_1 Tissue 4 46307612 C TGABRA2 p.G226R 0 85 0.206897 58 WCM4_X1_1 Tissue 4 6598902 C T MAN2B2p.R374* 0 60 0.204545 88 WCM4_X1_1 Tissue 4 7802247 C A AFAP1 p.E396D 033 0.078947 38 WCM4_X1_1 Tissue 6 145149949 A C UTRN p.N3208T 0 620.136364 44 WCM4_X1_1 Tissue 7 127224623 T G GCC1 p.E205A 0 222 0.075145173 WCM4_X1_1 Tissue 7 23871852 A C STK31 p.K976T 0 47 0.121212 33WCM4_X1_1 Tissue 7 87175277 C T ABCB1 p.V597I 0 99 0.202247 89 WCM4_X1_1Tissue 7 99711692 G C TAF6 p.I47M 0 131 0.149123 114 WCM4_X1_1 Tissue 8142264769 C T RP11- p.R16W 0 99 0.068627 102 WCM4_X1_1 Tissue 10J21.3 82830812 G T CSMD1 p.P2918H 0 198 0.253886 193 WCM4_X1_1 Tissue 893029459 G C RUNX1T1 p.T74R 0 125 0.113333 150 WCM4_X1_1 Tissue 9131899885 G T PPP2R4 p.E269* 0 52 0.082353 85 WCM4_X1_1 Tissue 9 4697857G A CDC37L1 p.R242H 0 106 0.333333 81 WCM4_X1_1 Tissue 9 97062956 G TZNF169 p.R372S 0 81 0.217391 69 WCM4_X1_1 Tissue 9 98209630 C T PTCH1p.R1303H 0 36 0.111111 45 WCM4_X1_1 Tissue X 230852 T C GTPBP6 p.Y12C 0133 0.062937 143 WCM4_X1_1 Tissue X 47428973 G A ARAF p.G446S 0 710.181818 77 WCM4_X1_1 Tissue 1 46745215 T C LRRC41 p.M698V 0 39 0.13043546 WCM63 Plasma 5 109961101 T G TMEM232 p.Y212S 0 45 0.131579 38 WCM63Plasma 17 58740529 C A PPM1D p.C478* 0 75 0.068966 87 WCM63_X1_1 Tissue10 875667 T G LARP4B p.K290T 0 91 0.458333 48 WCM63_Z1_1 Tissue 1131812342 G A PAX6 p.R367W 0 173 0.448598 107 WCM63_Z1_1 Tissue 1136615571 C A RAG2 p.V50L 0 133 0.081081 74 WCM63_Z1_1 Tissue 1 204429736A G PIK3C2B p.I455T 0 123 0.661417 127 WCM63_Z1_1 Tissue 12 10978862 G ATAS2R10 p.R3C 0 152 0.05988 167 WCM63_Z1_1 Tissue 12 49956852 C T MCRS1p.R246H 0 95 0.3 100 WCM63_Z1_1 Tissue 1 42915676 C A ZMYND12 p.Q55H 086 0.0625 48 WCM63_Z1_1 Tissue 1 46745215 T C LRRC41 p.M698V 0 560.418605 43 WCM63_Z1_1 Tissue 15 65115985 G T PIF1 p.P184T 0 66 0.07317141 WCM63_Z1_1 Tissue 17 4619316 G A ARRB2 p.V35M 0 318 0.096573 321WCM63_Z1_1 Tissue 17 7733675 C T DNAH2 p.R3971C 0 40 0.475 40 WCM63_Z1_1Tissue 17 79078454 A G BAIAP2 p.T403A 0 182 0.081897 232 WCM63_Z1_1Tissue 19 58928537 G A ZNF584 p.E218K 0 211 0.365217 230 WCM63_Z1_1Tissue 20 25255333 G A PYGB p.D212N 0 40 0.06383 47 WCM63_Z1_1 Tissue 2143298859 C T PRDM15 p.V120I 0 79 0.61039 77 WCM63_Z1_1 Tissue 2170428478 A T FASTKD1 p.I21N 0 71 0.416667 60 WCM63_Z1_1 Tissue 2173955871 C A MLTK p.Q38K 0 80 0.134831 89 WCM63_Z1_1 Tissue 2 200137128C T SATB2 p.V670M 0 218 0.668085 235 WCM63_Z1_1 Tissue 3 27243026 C TNEK10 p.E756K 0 206 0.257812 128 WCM63_Z1_1 Tissue 3 57327915 G A DNAH12p.T3058M 0 84 0.246377 69 WCM63_Z1_1 Tissue 4 126370155 G C FAT4p.V2662L 0 121 0.514286 140 WCM63_Z1_1 Tissue 4 2515449 G A RNF4 p.C159Y0 45 0.388889 36 WCM63_Z1_1 Tissue 4 4249835 G A TMEM128 p.P32L 0 560.55814 43 WCM63_Z1_1 Tissue 5 167887678 C G WWC1 p.S949R 0 130 0.476636107 WCM63_Z1_1 Tissue 5 180278443 C G ZFP62 p.E18Q 0 157 0.09009 111WCM63_Z1_1 Tissue 6 160679519 G A SLC22A2 p.R91C 0 119 0.305263 95WCM63_Z1_1 Tissue 7 147600770 G T CNTNAP2 p.D738Y 0 47 0.285714 35WCM63_Z1_1 Tissue 9 120053634 G A ASTN2 p.Q201* 0 80 0.323944 71WCM63_Z1_1 Tissue X 114424515 G T RBMXL3 p.A171S 0 48 0.066667 45WCM63_Z1_1 Tissue 2 148684711 A T ACVR2A p.L470F 0 49 0.076923 52WCM63_Z19_1 Tissue 9 130224560 G T LRSAM1 p.V146L 0 61 0.071429 42WCM63_Z19_1 Tissue 9 135139810 G A SETX p.T2617M 0 44 0.085714 35WCM63_Z19_1 Tissue 9 139743992 C A PHPT1 p.A37D 0 36 0.050847 59WCM63_Z19_1 Tissue 10 6498648 G T PRKCQ p.Y545* 0 152 0.182692 104WCM63_Z19_2 Tissue 10 875667 T G LARP4B p.K290T 0 91 0.327586 58WCM63_Z19_2 Tissue 11 30925144 C A DCDC1 p.L1465F 0 90 0.115942 69WCM63_Z19_2 Tissue 11 31812342 G A PAX6 p.R367W 0 173 0.318681 182WCM63_Z19_2 Tissue 1 204429736 A G PIK3C2B p.I455T 0 123 0.466667 60WCM63_Z19_2 Tissue 12 109505367 G C USP30 p.D139H 0 228 0.285714 217WCM63_Z19_2 Tissue 12 109505411 G C USP30 p.Q153H 0 154 0.114458 166WCM63_Z19_2 Tissue 12 47163207 C T SLC38A4 p.R435H 0 80 0.186813 91WCM63_Z19_2 Tissue 12 49956852 C T MCRS1 p.R246H 0 95 0.171429 70WCM63_Z19_2 Tissue 13 61986417 G T PCDH20 p.Y605* 0 87 0.083333 36WCM63_Z19_2 Tissue 1 46745215 T C LRRC41 p.M698V 0 56 0.214286 42WCM63_Z19_2 Tissue 17 7749246 G T KDM6B p.G65V 0 77 0.075 40 WCM63_Z19_2Tissue 19 58928537 G A ZNF584 p.E218K 0 211 0.282486 177 WCM63_Z19_2Tissue 20 7894922 C T HAO1 p.R145Q 0 276 0.307692 91 WCM63_Z19_2 Tissue21 43298859 C T PRDM15 p.V120I 0 79 0.342105 76 WCM63_Z19_2 Tissue 2200137128 C T SATB2 p.V670M 0 218 0.545977 174 WCM63_Z19_2 Tissue 327243026 C T NEK10 p.E756K 0 206 0.173611 144 WCM63_Z19_2 Tissue 4126370155 G C FAT4 p.V2662L 0 121 0.454545 66 WCM63_Z19_2 Tissue 42515449 G A RNF4 p.C159Y 0 45 0.421875 64 WCM63_Z19_2 Tissue 4 4249835 GA TMEM128 p.P32L 0 56 0.346154 52 WCM63_Z19_2 Tissue 9 120053634 G AASTN2 p.Q201* 0 80 0.202128 94 WCM63_Z19_2 Tissue 10 90768668 C A FASp.C119* 0 48 0.06383 47 WCM63_Z2_1 Tissue 11 118375124 C A KMT2Ap.N2836K 0 74 0.078431 51 WCM63_Z2_1 Tissue 1 204429736 A G PIK3C2Bp.I455T 0 71 0.395604 91 WCM63_Z2_1 Tissue 1 224345357 G T FBXO28p.G339V 0 46 0.068182 44 WCM63_Z2_1 Tissue 12 49956852 C T MCRS1 p.R246H0 139 0.476923 130 WCM63_Z2_1 Tissue 16 51171049 C A SALL1 p.D1317Y 0248 0.206009 233 WCM63_Z2_1 Tissue 17 7224478 C T NEURL4 p.G1105S 0 1710.065421 107 WCM63_Z2_1 Tissue 18 44682601 G T IER3IP1 p.P66T 0 320.081081 37 WCM63_Z2_1 Tissue 2 200137128 C T SATB2 p.V670M 0 1770.720721 111 WCM63_Z2_1 Tissue 2 98411451 C A TMEM131 p.A1110S 0 580.096154 52 WCM63_Z2_1 Tissue 4 126370155 G C FAT4 p.V2662L 0 1670.408602 186 WCM63_Z2_1 Tissue 4 2515449 G A RNF4 p.C159Y 0 45 0.39024441 WCM63_Z2_1 Tissue 5 167887678 C G WWC1 p.S949R 0 101 0.397727 88WCM63_Z2_1 Tissue 7 107572789 C T LAMB1 p.E1408K 0 142 0.081301 123WCM63_Z2_1 Tissue 7 143884051 C T ARHGEF35 p.D476N 0 67 0.181818 77WCM63_Z2_1 Tissue 7 99474164 G T OR2AE1 p.H165N 0 47 0.076923 52WCM63_Z2_1 Tissue 10 59956376 G A IPMK p.Q238* 0 67 0.227273 66 WCM677Plasma 11 102986019 G C DYNC2H1 p.A206P 0 84 0.233766 77 WCM677 Plasma11 10781764 A G CTR9 p.K213E 0 91 0.288889 90 WCM677 Plasma 11 7437381 AC SYT9 p.T385P 0 55 0.260274 73 WCM677 Plasma 1 85431277 C A MCOLN2p.W64C 0 83 0.317073 82 WCM677 Plasma 19 49459028 G T BAX p.K57N 0 490.27451 51 WCM677 Plasma 20 48503379 G A SLC9A8 p.V528M 0 62 0.132075 53WCM677 Plasma 21 39671379 A G KCNJ15 p.K66E 0 45 0.233333 60 WCM677Plasma 2 179449648 C T TTN p.A19933T 0 56 0.37037 54 WCM677 Plasma 220871119 C A GDF7 p.D429E 0 31 0.282051 39 WCM677 Plasma 2 61417443 C TUSP34 p.R3279Q 0 75 0.338028 71 WCM677 Plasma 2 8946477 C G KIDINS220p.W176S 0 88 0.310811 74 WCM677 Plasma 3 52019234 G T ACY1 p.A36S 0 400.076923 39 WCM677 Plasma 5 112328389 C G DCP2 p.Y118* 0 79 0.276316 76WCM677 Plasma 5 121787096 G A SNCAIP p.E852K 0 59 0.277778 72 WCM677Plasma 5 177019246 C T TMED9 p.R11W 0 76 0.078947 38 WCM677 Plasma 5179023579 C T RUFY1 p.R510W 0 36 0.085714 35 WCM677 Plasma 6 144171349 GC LTV1 p.V131L 0 58 0.338462 65 WCM677 Plasma 6 47846116 G A PTCHD4p.R822C 0 67 0.164706 85 WCM677 Plasma 6 88173748 G A C6orf165 p.R550H 071 0.142857 49 WCM677 Plasma 7 42006083 C T GLI3 p.R863H 0 49 0.09677431 WCM677 Plasma 7 42018209 G A GLI3 p.H546Y 0 41 0.145161 62 WCM677Plasma 7 47384421 C T TNS3 p.R861H 0 49 0.285714 42 WCM677 Plasma 9135493798 G A DDX31 p.R687* 0 43 0.1875 64 WCM677 Plasma 9 77473606 G ATRPM6 p.P31L 0 61 0.1 70 WCM677 Plasma X 32563321 G T DMD p.P708H 0 380.708333 48 WCM677 Plasma 10 98307663 G T TM9SF3 p.A348D 0 43 0.06383 47WCM677_Z12_1 Tissue 11 102986019 G C DYNC2H1 p.A206P 0 69 0.235294 68WCM677_Z12_1 Tissue 11 10781764 A G CTR9 p.K213E 0 31 0.4 40WCM677_Z12_1 Tissue 11 33689540 C T KIAA1549L p.P1797L 0 51 0.409091 66WCM677_Z12_1 Tissue 11 4407050 G A TRIM21 p.P298L 0.003759 266 0.188153287 WCM677_Z12_1 Tissue 11 7437381 A C SYT9 p.T385P 0 39 0.375 56WCM677_Z12_1 Tissue 12 120156534 G C CIT p.R1283G 0 42 0.086957 69WCM677_Z12_1 Tissue 12 12967155 C A DDX47 p.Q60K 0 74 0.076923 39WCM677_Z12_1 Tissue 14 24731311 C T TGM1 p.R83Q 0 156 0.245902 244WCM677_Z12_1 Tissue 17 40282409 C T RAB5C p.V38I 0 284 0.219178 365WCM677_Z12_1 Tissue 19 49459028 G T BAX p.K57N 0 95 0.561151 139WCM677_Z12_1 Tissue 20 48503379 G A SLC9A8 p.V528M 0 99 0.351145 131WCM677_Z12_1 Tissue 21 39671379 A G KCNJ15 p.K66E 0 63 0.421053 95WCM677_Z12_1 Tissue 2 179449648 C T TTN p.A19933T 0 34 0.666667 48WCM677_Z12_1 Tissue 2 20871119 C A GDF7 p.D429E 0 140 0.556701 194WCM677_Z12_1 Tissue 2 232100020 G A ARMC9 p.A236T 0 207 0.079646 113WCM677_Z12_1 Tissue 2 61417443 C T USP34 p.R3279Q 0 52 0.47191 89WCM677_Z12_1 Tissue 2 8946477 C G KIDINS220 p.W176S 0 93 0.52 125WCM677_Z12_1 Tissue 3 126736332 G A PLXNA1 p.R1114H 0 38 0.338028 71WCM677_Z12_1 Tissue 3 168838970 G A MECOM p.R148W 0 90 0.379747 79WCM677_Z12_1 Tissue 5 112328389 C G DCP2 p.Y118* 0 39 0.40678 59WCM677_Z12_1 Tissue 5 121787096 G A SNCAIP p.E852K 0 81 0.555556 108WCM677_Z12_1 Tissue 5 79031102 A C CMYA5 p.K2172Q 0 31 0.69697 33WCM677_Z12_1 Tissue 6 47846116 G A PTCHD4 p.R822C 0 136 0.280374 107WCM677_Z12_1 Tissue 7 47384421 C T TNS3 p.R861H 0 88 0.46875 128WCM677_Z12_1 Tissue 9 135493798 G A DDX31 p.R687* 0 164 0.113537 229WCM677_Z12_1 Tissue 9 77473606 G A TRPM6 p.P31L 0 34 0.096154 52WCM677_Z12_1 Tissue 11 102986019 G C DYNC2H1 p.A206P 0 69 0.380952 63WCM677_Z16_1 Tissue 11 10781764 A G CTR9 p.K213E 0 31 0.6 35WCM677_Z16_1 Tissue 11 33689540 C T KIAA1549L p.P1797L 0 51 0.491228 57WCM677_Z16_1 Tissue 11 4407050 G A TRIM21 p.P298L 0.003759 266 0.210345290 WCM677_Z16_1 Tissue 11 7437381 A C SYT9 p.T385P 0 39 0.349206 63WCM677_Z16_1 Tissue 16 88951490 C G CBFA2T3 p.D361H 0 253 0.469799 149WCM677_Z16_1 Tissue 19 49459028 G T BAX p.K57N 0 95 0.385965 171WCM677_Z16_1 Tissue 20 48503379 G A SLC9A8 p.V528M 0 99 0.377358 159WCM677_Z16_1 Tissue 21 39671379 A G KCNJ15 p.K66E 0 63 0.537736 106WCM677_Z16_1 Tissue 2 179449648 C T TTN p.A19933T 0 34 0.631579 38WCM677_Z16_1 Tissue 2 20871119 C A GDF7 p.D429E 0 140 0.59116 181WCM677_Z16_1 Tissue 2 61417443 C T USP34 p.R3279Q 0 52 0.471429 70WCM677_Z16_1 Tissue 2 8946477 C G KIDINS220 p.W176S 0 93 0.475728 103WCM677_Z16_1 Tissue 3 126736332 G A PLXNA1 p.R1114H 0 38 0.45 60WCM677_Z16_1 Tissue 3 168838970 G A MECOM p.R148W 0 90 0.325926 135WCM677_Z16_1 Tissue 3 58552383 C T FAM107A p.E123K 0 189 0.167785 149WCM677_Z16_1 Tissue 5 112328389 C G DCP2 p.Y118* 0 39 0.2 60WCM677_Z16_1 Tissue 5 121787096 G A SNCAIP p.E852K 0 81 0.4 125WCM677_Z16_1 Tissue 5 79031102 A C CMYA5 p.K2172Q 0 31 0.394737 38WCM677_Z16_1 Tissue 6 47846116 G A PTCHD4 p.R822C 0 136 0.344828 116WCM677_Z16_1 Tissue 7 47384421 C T TNS3 p.R861H 0 88 0.510204 147WCM677_Z16_1 Tissue 9 135493798 G A DDX31 p.R687* 0 164 0.251082 231WCM677_Z16_1 Tissue 11 102986019 G C DYNC2H1 p.A206P 0 69 0.288462 52WCM677_Z3_1 Tissue 11 10781764 A G CTR9 p.K213E 0 31 0.545455 33WCM677_Z3_1 Tissue 11 33689540 C T KIAA1549L p.P1797L 0 51 0.35 40WCM677_Z3_1 Tissue 11 4407050 G A TRIM21 p.P298L 0.003759 266 0.129921254 WCM677_Z3_1 Tissue 11 5699583 C T TRIM5 p.E199K 0 68 0.131313 99WCM677_Z3_1 Tissue 11 7437381 A C SYT9 p.T385P 0 39 0.395349 43WCM677_Z3_1 Tissue 16 47001545 A C DNAJA2 p.S153A 0 100 0.484211 95WCM677_Z3_1 Tissue 17 32964784 C T TMEM132E p.R830C 0 53 0.081081 74WCM677_Z3_1 Tissue 17 79867447 G T PCYT2 p.Q41K 0 36 0.075 40WCM677_Z3_1 Tissue 19 49459028 G T BAX p.K57N 0 95 0.440367 109WCM677_Z3_1 Tissue 20 472926 T C CSNK2A1 p.K198R 0 45 0.4 35 WCM677_Z3_1Tissue 21 39671379 A G KCNJ15 p.K66E 0 63 0.382716 81 WCM677_Z3_1 Tissue2 179449648 C T TTN p.A19933T 0 34 0.789474 38 WCM677_Z3_1 Tissue 220871119 C A GDF7 p.D429E 0 140 0.461538 169 WCM677_Z3_1 Tissue 254753639 C G SPTBN1 p.D28E 0 38 0.23913 46 WCM677_Z3_1 Tissue 2 61417443C T USP34 p.R3279Q 0 52 0.397059 68 WCM677_Z3_1 Tissue 2 8946477 C GKIDINS220 p.W176S 0 93 0.4 125 WCM677_Z3_1 Tissue 3 126736332 G A PLXNA1p.R1114H 0 38 0.254902 51 WCM677_Z3_1 Tissue 3 168838970 G A MECOMp.R148W 0 90 0.329897 97 WCM677_Z3_1 Tissue 5 112328389 C G DCP2 p.Y118*0 39 0.269231 52 WCM677_Z3_1 Tissue 5 121787096 G A SNCAIP p.E852K 0 810.35 100 WCM677_Z3_1 Tissue 5 79031102 A C CMYA5 p.K2172Q 0 31 0.51428635 WCM677_Z3_1 Tissue 6 47846116 G A PTCHD4 p.R822C 0 136 0.168675 83WCM677_Z3_1 Tissue 7 47384421 C T TNS3 p.R861H 0 88 0.383721 86WCM677_Z3_1 Tissue X 128710479 C A OCRL p.R689S 0 47 0.054545 55WCM677_Z3_1 Tissue X 21627460 G A CNKSR2 p.R806Q 0 97 0.275862 87WCM677_Z3_1 Tissue 11 102986019 G C DYNC2H1 p.A206P 0 69 0.155172 58WCM677_Z6_1 Tissue 11 32956037 C A QSER1 p.T949K 0 42 0.050847 59WCM677_Z6_1 Tissue 11 33689540 C T KIAA1549L p.P1797L 0 51 0.396226 53WCM677_Z6_1 Tissue 11 4407050 G A TRIM21 p.P298L 0.003759 266 0.164474304 WCM677_Z6_1 Tissue 11 5699583 C T TRIM5 p.E199K 0 68 0.257353 136WCM677_Z6_1 Tissue 11 7437381 A C SYT9 p.T385P 0 39 0.612245 49WCM677_Z6_1 Tissue 19 12812628 T C TNPO2 p.K817E 0 285 0.164179 268WCM677_Z6_1 Tissue 19 49459028 G T BAX p.K57N 0 95 0.485075 134WCM677_Z6_1 Tissue 20 472926 T C CSNK2A1 p.K198R 0 45 0.363636 33WCM677_Z6_1 Tissue 21 39671379 A G KCNJ15 p.K66E 0 63 0.483871 124WCM677_Z6_1 Tissue 2 179449648 C T TTN p.A19933T 0 34 0.666667 39WCM677_Z6_1 Tissue 2 20871119 C A GDF7 p.D429E 0 140 0.503067 163WCM677_Z6_1 Tissue 2 25799751 C T DTNB p.G278S 0 65 0.24 75 WCM677_Z6_1Tissue 2 54753639 C G SPTBN1 p.D28E 0 38 0.340909 44 WCM677_Z6_1 Tissue2 61417443 C T USP34 p.R3279Q 0 52 0.646154 65 WCM677_Z6_1 Tissue 28946477 C G KIDINS220 p.W176S 0 93 0.632479 117 WCM677_Z6_1 Tissue 3126736332 G A PLXNA1 p.R1114H 0 38 0.21519 79 WCM677_Z6_1 Tissue 3168838970 G A MECOM p.R148W 0 90 0.378205 156 WCM677_Z6_1 Tissue 4153897264 C T FHDC1 p.R941C 0 101 0.060403 149 WCM677_Z6_1 Tissue 5112328389 C G DCP2 p.Y118* 0 39 0.129032 62 WCM677_Z6_1 Tissue 5121787096 G A SNCAIP p.E852K 0 81 0.276119 134 WCM677_Z6_1 Tissue 531483728 C A DROSHA p.L668F 0 36 0.145833 48 WCM677_Z6_1 Tissue 579031102 A C CMYA5 p.K2172Q 0 31 0.488372 43 WCM677_Z6_1 Tissue 647846116 G A PTCHD4 p.R822C 0 136 0.130769 130 WCM677_Z6_1 Tissue 747384421 C T TNS3 p.R861H 0 88 0.397163 141 WCM677_Z6_1 Tissue X70836268 G A CXCR3 p.R352C 0 37 0.061224 49 WCM677_Z6_1 Tissue 11102986019 G C DYNC2H1 p.A206P 0 69 0.255319 47 WCM677_Z7_1 Tissue 1114540549 G T PSMA1 p.S14R 0 41 0.065217 46 WCM677_Z7_1 Tissue 1133689540 C T KIAA1549L p.P1797L 0 51 0.487805 41 WCM677_Z7_1 Tissue 114407050 G A TRIM21 p.P298L 0.003759 266 0.175 240 WCM677_Z7_1 Tissue 115699583 C T TRIM5 p.E199K 0 68 0.145833 144 WCM677_Z7_1 Tissue 117437381 A C SYT9 p.T385P 0 39 0.615385 52 WCM677_Z7_1 Tissue 16 47001545A C DNAJA2 p.S153A 0 100 0.519685 127 WCM677_Z7_1 Tissue 19 49459028 G TBAX p.K57N 0 95 0.435714 140 WCM677_Z7_1 Tissue 20 472926 T C CSNK2A1p.K198R 0 45 0.382353 34 WCM677_Z7_1 Tissue 21 39671379 A G KCNJ15p.K66E 0 63 0.486726 113 WCM677_Z7_1 Tissue 2 179449648 C T TTNp.A19933T 0 34 0.756757 37 WCM677_Z7_1 Tissue 2 20871119 C A GDF7p.D429E 0 140 0.586021 186 WCM677_Z7_1 Tissue 2 54753639 C G SPTBN1p.D28E 0 38 0.2 35 WCM677_Z7_1 Tissue 2 61417443 C T USP34 p.R3279Q 0 520.586207 58 WCM677_Z7_1 Tissue 2 8946477 C G KIDINS220 p.W176S 0 930.495146 103 WCM677_Z7_1 Tissue 3 126736332 G A PLXNA1 p.R1114H 0 380.351648 91 WCM677_Z7_1 Tissue 3 168838970 G A MECOM p.R148W 0 900.317073 123 WCM677_Z7_1 Tissue 5 112328389 C G DCP2 p.Y118* 0 390.47619 42 WCM677_Z7_1 Tissue 5 121787096 G A SNCAIP p.E852K 0 810.357143 126 WCM677_Z7_1 Tissue 5 79031102 A C CMYA5 p.K2172Q 0 310.547619 42 WCM677_Z7_1 Tissue 6 47846116 G A PTCHD4 p.R822C 0 1360.207792 77 WCM677_Z7_1 Tissue 7 47384421 C T TNS3 p.R861H 0 88 0.558559111 WCM677_Z7_1 Tissue 10 69948713 C T MYPN p.R919C 0 96 0.074074 81WCM677_Z9_1 Tissue 11 102986019 G C DYNC2H1 p.A206P 0 69 0.349206 63WCM677_Z9_1 Tissue 11 10781764 A G CTR9 p.K213E 0 31 0.540541 37WCM677_Z9_1 Tissue 11 33689540 C T KIAA1549L p.P1797L 0 51 0.390625 64WCM677_Z9_1 Tissue 11 4407050 G A TRIM21 p.P298L 0.003759 266 0.174377281 WCM677_Z9_1 Tissue 11 5699583 C T TRIM5 p.E199K 0 68 0.281818 110WCM677_Z9_1 Tissue 11 7437381 A C SYT9 p.T385P 0 39 0.467742 62WCM677_Z9_1 Tissue 16 47001545 A C DNAJA2 p.S153A 0 100 0.46281 121WCM677_Z9_1 Tissue 17 39156020 C T KRTAP3-2 p.G29E 0 150 0.086758 219WCM677_Z9_1 Tissue 19 49459028 G T BAX p.K57N 0 95 0.454545 121WCM677_Z9_1 Tissue 20 472926 T C CSNK2A1 p.K198R 0 45 0.378378 37WCM677_Z9_1 Tissue 21 39671379 A G KCNJ15 p.K66E 0 63 0.631068 103WCM677_Z9_1 Tissue 2 179449648 C T TTN p.A19933T 0 34 0.621622 37WCM677_Z9_1 Tissue 2 20871119 C A GDF7 p.D429E 0 140 0.395349 172WCM677_Z9_1 Tissue 2 54753639 C G SPTBN1 p.D28E 0 38 0.272727 44WCM677_Z9_1 Tissue 2 61417443 C T USP34 p.R3279Q 0 52 0.410714 56WCM677_Z9_1 Tissue 2 8946477 C G KIDINS220 p.W176S 0 93 0.557895 95WCM677_Z9_1 Tissue 3 126736332 G A PLXNA1 p.R1114H 0 38 0.258065 62WCM677_Z9_1 Tissue 3 168838970 G A MECOM p.R148W 0 90 0.276119 134WCM677_Z9_1 Tissue 3 38655281 C T SCN5A p.R219H 0 32 0.06 50 WCM677_Z9_1Tissue 5 112328389 C G DCP2 p.Y118* 0 39 0.375 56 WCM677_Z9_1 Tissue 5121787096 G A SNCAIP p.E852K 0 81 0.34127 126 WCM677_Z9_1 Tissue 579031102 A C CMYA5 p.K2172Q 0 31 0.516129 31 WCM677_Z9_1 Tissue 647846116 G A PTCHD4 p.R822C 0 136 0.307018 114 WCM677_Z9_1 Tissue 747384421 C T TNS3 p.R861H 0 88 0.436975 119 WCM677_Z9_1 Tissue 1117548809 G A USH1C p.L153F 0 41 0.608696 46 WCM6_Z5_1 Tissue 11 47364249G C MYBPC3 p.R502G 0 81 0.181818 77 WCM6_Z5_1 Tissue 11 5172835 G TOR52A1 p.Y255* 0 100 0.346154 78 WCM6_Z5_1 Tissue 11 68153886 G A LRP5p.R373Q 0 87 0.065789 76 WCM6_Z5_1 Tissue 1 17266398 G C CROCC p.G540R 0386 0.142857 287 WCM6_Z5_1 Tissue 1 179452274 C T AXDND1 p.A670V 0 900.356436 101 WCM6_Z5_1 Tissue 1 179526218 G T NPHS2 p.H228N 0 483 0.38450 WCM6_Z5_1 Tissue 1 181702853 G A CACNA1E p.V1077M 0 174 0.200893 224WCM6_Z5_1 Tissue 11 92533273 G T FAT3 p.R2365I 0 104 0.12069 58WCM6_Z5_1 Tissue 1 215751377 G A KCTD3 p.R117H 0 32 0.394737 38WCM6_Z5_1 Tissue 1 216246565 C A USH2A p.V1884F 0 113 0.544118 136WCM6_Z5_1 Tissue 15 54015072 C A WDR72 p.A63S 0 54 0.068182 44 WCM6_Z5_1Tissue 16 84096991 A G MBTPS1 p.Y831H 0 229 0.842105 133 WCM6_Z5_1Tissue 17 43003524 T C KIF18B p.N828S 0 113 0.220779 154 WCM6_Z5_1Tissue 17 7415226 C T POLR2A p.L1400F 0 102 0.315789 95 WCM6_Z5_1 Tissue19 38857947 G A CATSPERG p.R922Q 0 50 0.536585 41 WCM6_Z5_1 Tissue 1942754648 T G ERF p.H31P 0 55 0.875 32 WCM6_Z5_1 Tissue 19 50940930 C TMYBPC2 p.S176L 0 178 0.47343 207 WCM6_Z5_1 Tissue 2 217528711 C G IGFBP2p.P288A 0 196 0.321429 168 WCM6_Z5_1 Tissue 2 236957874 T G AGAP1p.V688G 0 96 0.371795 78 WCM6_Z5_1 Tissue 2 28772920 C T PLB1 p.T351I 0167 0.304348 115 WCM6_Z5_1 Tissue 3 197619565 A T IQCG p.N343K 0 970.185841 113 WCM6_Z5_1 Tissue 3 48465272 C T PLXNB1 p.R250Q 0 850.137615 109 WCM6_Z5_1 Tissue 3 57276166 T G APPL1 p.S137R 0 65 0.58823568 WCM6_Z5_1 Tissue 4 79207636 G A FRAS1 p.G493R 0 49 0.444444 54WCM6_Z5_1 Tissue 5 75913928 G A F2RL2 p.R202W 0 179 0.279221 154WCM6_Z5_1 Tissue 7 139268785 C T HIPK2 p.V915I 0 120 0.649007 151WCM6_Z5_1 Tissue 8 107719065 A G OXR1 p.D440G 0 44 0.604938 81 WCM6_Z5_1Tissue 9 101830900 C A COL15A1 p.H1301N 0 184 0.216667 240 WCM6_Z5_1Tissue 9 136037796 G A GBGT1 p.H2Y 0 102 0.12987 154 WCM6_Z5_1 Tissue Y3447355 C A TGIF2LY p.Q24K 0 32 0.95 40 WCM6_Z5_1 Tissue 12 106853096 GT POLR3B p.L840F 0 32 0.103093 97 WCM7 Plasma 18 48591919 G A SMAD4p.R361H 0 37 0.07 100 WCM7 Plasma 3 196867113 C T DLG1 p.S237N 0 410.074766 107 WCM7 Plasma 5 140475645 C A PCDHB2 p.T424N 0 44 0.145631103 WCM7 Plasma 6 56880044 A T BEND6 p.N138Y 0 34 0.114583 96 WCM7Plasma 9 94495617 G A ROR2 p.R242C 0 56 0.099099 111 WCM7 Plasma 11118220630 G T CD3G p.M84I 0 34 0.083333 36 WCM73 Plasma 1 150680815 C THORMAD1 p.R155H 0 56 0.078431 51 WCM73 Plasma 13 109318453 C T MYO16p.T61M 0 33 0.075472 53 WCM73 Plasma 19 38958339 G C RYR1 p.E1090Q 0 320.088889 45 WCM73 Plasma 2 158971760 C T UPP2 p.L110F 0 31 0.078947 38WCM73 Plasma 2 204322299 T C RAPH1 p.K371R 0 36 0.081081 37 WCM73 Plasma2 220312964 G A SPEG p.G362R 0 32 0.076923 39 WCM73 Plasma 9 15848935 CT CCDC171 p.T1153M 0 34 0.069767 43 WCM73 Plasma 1 1153946 G T SDF4p.N268K 0 260 0.21875 256 WCM73_X1_1 Tissue 12 56031070 G A OR10P1p.R132H 0 594 0.153101 516 WCM73_X1_1 Tissue 12 58152463 G C 9-Marp.G275A 0 224 0.125581 215 WCM73_X1_1 Tissue 14 99924635 T C SETD3p.Y219C 0 39 0.171429 35 WCM73_X1_1 Tissue 15 74425513 C T ISLR2 p.R140W0 68 0.210526 57 WCM73_X1_1 Tissue 19 16770221 T C SMIM7 p.R36G 0 1280.146341 123 WCM73_X1_1 Tissue 19 2403164 G T TMPRSS9 p.C180F 0 680.107692 65 WCM73_X1_1 Tissue 19 38958339 G C RYR1 p.E1090Q 0 1120.151724 145 WCM73_X1_1 Tissue 19 52469245 G C ZNF350 p.S154C 0 1100.158537 82 WCM73_X1_1 Tissue 20 46301083 C T SULF2 p.G479S 0 1100.233645 107 WCM73_X1_1 Tissue 20 61513674 C T DIDO1 p.D1212N 0 1140.191011 89 WCM73_X1_1 Tissue 2 207619823 G A MDH1B p.R274C 0 770.142857 84 WCM73_X1_1 Tissue 2 218675010 G T TNS1 p.P1585T 0 1430.198198 111 WCM73_X1_1 Tissue 2 70408858 C T C2orf42 p.R87Q 0 1190.204545 132 WCM73_X1_1 Tissue 3 47470079 C A SCAP p.V112L 0 41 0.10344858 WCM73_X1_1 Tissue 5 140481852 C A PCDHB3 p.A540D 0 32 0.090909 33WCM73_X1_1 Tissue 7 98555641 C T TRRAP p.S2083F 0 84 0.180851 94WCM73_X1_1 Tissue 9 131115331 C T SLC27A4 p.R339C 0 59 0.06383 47WCM73_X1_1 Tissue X 102931244 T C MORF4L2 p.M238V 0 98 0.064815 108WCM73_X1_1 Tissue X 125298904 C T DCAP12L2 p.R335H 0 110 0.091954 87WCM73_X1_1 Tissue 10 48382209 G A RBP3 p.T1147M 0 38 0.109589 73 WCM78Plasma 1 102271668 C T OLFM3 p.W241* 0 65 0.145455 110 WCM78 Plasma 1278520960 A G NAV3 p.R1418G 0 58 0.090909 99 WCM78 Plasma 12 95461124 C TNR2C1 p.E13K 0 53 0.093458 107 WCM78 Plasma 12 98993884 A C SLC25A3p.T266P 0 35 0.096774 62 WCM78 Plasma 14 23900801 G A MYH7 p.S242F 0 510.095652 115 WCM78 Plasma 14 79181393 G T NRXN3 p.C279F 0 41 0.051948 77WCM78 Plasma 15 50535413 G T HDC p.S390Y 0 33 0.129412 85 WCM78 Plasma17 37680959 G A CDK12 p.W1043* 0 59 0.206186 97 WCM78 Plasma 17 38027738C T ZPBP2 p.T89I 0 54 0.158879 107 WCM78 Plasma 17 38711861 C G CCR7p.K90N 0 49 0.159574 94 WCM78 Plasma 17 61628127 A G DCAF7 p.K30R 0 440.155844 77 WCM78 Plasma 17 8170770 G C PFAS p.A1086P 0 47 0.070423 71WCM78 Plasma 18 28720116 T A DSC1 p.E470V 0 48 0.084211 95 WCM78 Plasma18 346996 A C COLEC12 p.L209R 0 43 0.084337 83 WCM78 Plasma 19 9065391 AT MUC16 p.V7352E 0 48 0.125 88 WCM78 Plasma 20 35563511 G A SAMHD1p.L144F 0 49 0.087912 91 WCM78 Plasma 2 141108374 C A LRP1B p.G3962C 058 0.142857 91 WCM78 Plasma 2 202257645 C A TRAK2 p.G367V 0 54 0.08695769 WCM78 Plasma 2 210761127 C T UNC80 p.S1458L 0 46 0.054348 92 WCM78Plasma 22 26830423 C T ASPHD2 p.T281M 0 56 0.15 80 WCM78 Plasma 2241465794 G A ANKMY1 p.P252L 0 48 0.08642 81 WCM78 Plasma 22 42003846 GC DESI1 p.I36M 0 43 0.053191 94 WCM78 Plasma 5 112884245 C G YTHDC2p.Y501* 0 50 0.128205 78 WCM78 Plasma 5 89695331 C A CETN3 p.E102* 0 620.082474 97 WCM78 Plasma 6 132939067 C T TAAR2 p.G93E 0 51 0.1875 80WCM78 Plasma 7 100633889 C A MUC12 p.F158L 0 34 0.148649 74 WCM78 Plasma8 133898711 C T TG p.A365V 0 37 0.055556 72 WCM78 Plasma 8 43024371 C THGSNAT p.R235C 0 60 0.107843 102 WCM78 Plasma 10 24922371 C A ARHGAP21p.G134C 0 48 0.082192 73 WCM78_Z1_1 Tissue 10 24922403 C A ARHGAP21p.R123L 0 48 0.082192 73 WCM78_Z1_1 Tissue 10 48382209 G A RBP3 p.T1147M0 65 0.283333 60 WCM78_Z1_1 Tissue 1 102271668 C T OLFM3 p.W241* 0 920.324324 74 WCM78_Z1_1 Tissue 11 119025562 G A ABCG4 p.R208H 0 1280.110497 181 WCM78_Z1_1 Tissue 11 130275813 G C ADAMTS8 p.I770M 0 1020.093023 86 WCM78_Z1_1 Tissue 12 6697048 G A CHD4 p.A1178V 0 1570.503731 268 WCM78_Z1_1 Tissue 12 78520960 A G NAV3 p.R1418G 0 1400.418079 177 WCM78_Z1_1 Tissue 12 98993884 A C SLC25A3 p.T266P 0 870.306931 101 WCM78_Z1_1 Tissue 13 113496617 C T ATP11A p.A578V 0 650.073171 82 WCM78_Z1_1 Tissue 14 23900801 G A MYH7 p.S242F 0 195 0.12619420 WCM78_Z1_1 Tissue 15 33916174 C A RYR3 p.Q842K 0 41 0.282609 46WCM78_Z1_1 Tissue 15 50535413 G T HDC p.S390Y 0 171 0.344595 148WCM78_Z1_1 Tissue 16 16138529 G C ABCC1 p.Q344H 0 86 0.307692 156WCM78_Z1_1 Tissue 16 28502861 G C CLN3 p.P23A 0 67 0.226415 53WCM78_Z1_1 Tissue 16 840208 G A CHTF18 p.G213D 0 36 0.172414 58WCM78_Z1_1 Tissue 17 37680959 G A CDK12 p.W1043* 0 41 0.442623 61WCM78_Z1_1 Tissue 17 38643491 G C TNS4 p.P362R 0 206 0.050167 299WCM78_Z1_1 Tissue 17 38711861 C G CCR7 p.K90N 0 74 0.522388 134WCM78_Z1_1 Tissue 17 59668349 C A NACA2 p.G65C 0 37 0.061224 49WCM78_Z1_1 Tissue 18 28720116 T A DSC1 p.E470V 0 423 0.224138 464WCM78_Z1_1 Tissue 18 346996 A C COLEC12 p.L209R 0 64 0.236842 76WCM78_Z1_1 Tissue 18 70461472 C A NETO1 p.E173D 0 106 0.069444 72WCM78_Z1_1 Tissue 19 59028764 C A ZBTB45 p.V93F 0 116 0.067227 119WCM78_Z1_1 Tissue 20 35563511 G A SAMHD1 p.L144F 0 228 0.301435 209WCM78_Z1_1 Tissue 20 57768580 C T ZNF831 p.P836S 0 268 0.198157 217WCM78_Z1_1 Tissue 2 141108374 C A LRP1B p.G3962C 0 75 0.149254 67WCM78_Z1_1 Tissue 2 152382475 A T NEB p.S5685R 0 108 0.095238 63WCM78_Z1_1 Tissue 2 202257645 C A TRAK2 p.G367V 0 45 0.329114 79WCM78_Z1_1 Tissue 2 210761127 C T UNC80 p.S1458L 0 98 0.245902 122WCM78_Z1_1 Tissue 22 26830423 C T ASPHD2 p.T281M 0 155 0.280488 164WCM78_Z1_1 Tissue 22 31688276 C A PIK3IP1 p.A19S 0 56 0.083333 36WCM78_Z1_1 Tissue 2 241465794 G A ANKMY1 p.P252L 0 139 0.53211 109WCM78_Z1_1 Tissue 22 42003846 G C DESI1 p.I36M 0 52 0.190476 63WCM78_Z1_1 Tissue 2 97403735 C T LMAN2L p.R86H 0 73 0.1 60 WCM78_Z1_1Tissue 4 187455223 G A MTNR1A p.R225C 0 93 0.211009 109 WCM78_Z1_1Tissue 4 48492375 C T ZAR1 p.R23W 0 187 0.51751 257 WCM78_Z1_1 Tissue 5112884245 C G YTHDC2 p.Y501* 0 56 0.367816 87 WCM78_Z1_1 Tissue 5176004674 G A CDHR2 p.V463I 0 231 0.076233 223 WCM78_Z1_1 Tissue 6136904799 T A MAP3K5 p.D1102V 0 194 0.105882 170 WCM78_Z1_1 Tissue 7100633889 C A MUC12 p.F158L 0 173 0.35545 211 WCM78_Z1_1 Tissue 8110587233 C T SYBU p.G632R 0 42 0.27027 37 WCM78_Z1_1 Tissue 8 113304826G C CSMD3 p.P2910A 0 66 0.263158 95 WCM78_Z1_1 Tissue 9 140076213 C AANAPC2 p.S463I 0 129 0.18254 126 WCM78_Z1_1 Tissue 11 17794107 C T KCNC1p.P489L 0 74 0.264151 53 WCM7_Tissue Tissue 12 106853096 G T POLR3Bp.L840F 0 58 0.340426 47 WCM7_Tissue Tissue 17 20156848 G A SPECC1p.A877T 0 63 0.275 40 WCM7_Tissue Tissue 17 27613283 C G NUFIP2 p.G577R0 154 0.337662 77 WCM7_Tissue Tissue 2 107049447 C T RGPD3 p.A805T 0 310.058824 85 WCM7_Tissue Tissue 22 25007172 G A GGT1 p.A42T 0 1670.083333 36 WCM7_Tissue Tissue 3 196867113 C T DLG1 p.S237N 0 47 0.2 55WCM7_Tissue Tissue 3 41266124 A G CTNNB1 p.T41A 0 59 0.392857 56WCM7_Tissue Tissue 3 56627669 G T CCDC66 p.V407F 0 37 0.083333 36WCM7_Tissue Tissue 4 39435929 C T KLB p.R309W 0 100 0.685714 35WCM7_Tissue Tissue 5 140475645 C A PCDHB2 p.T424N 0 191 0.428571 98WCM7_Tissue Tissue 5 14336754 G A TRIO p.R655Q 0 94 0.319444 72WCM7_Tissue Tissue 6 56880044 A T BEND6 p.N138Y 0 80 0.290909 55WCM7_Tissue Tissue 9 94495617 G A ROR2 p.R242C 0 105 0.4 35 WCM7_TissueTissue X 99662212 C T PCDH19 p.V462M 0 92 0.083333 36 WCM7_Tissue Tissue10 133948606 C T JAKMIP3 p.A304V 0 52 0.064516 62 WCM80 Plasma 1151630836 G C SNX27 p.W223C 0 48 0.233333 60 WCM80 Plasma 12 40852541 CA MUC19 p.L1106I 0 38 0.230769 39 WCM80 Plasma 14 102606487 A G WDR20p.Y76C 0 53 0.088235 34 WCM80 Plasma 15 92459662 G A SLCO3A1 p.R207Q 035 0.318182 66 WCM80 Plasma 17 11622752 G A DNAH9 p.R1885H 0 36 0.34090944 WCM80 Plasma 17 7808965 C T CHD3 p.R1389W 0 35 0.081081 37 WCM80Plasma 19 14866513 C T EMR2 p.D457N 0 46 0.285714 63 WCM80 Plasma 1917313977 G A MYO9B p.V1634M 0 40 0.069767 43 WCM80 Plasma 19 18311231 GA RAB3A p.R85W 0 66 0.223684 76 WCM80 Plasma 19 52619693 G C ZNF616p.Q242E 0 36 0.319149 47 WCM80 Plasma 2 186678471 A G FSIP2 p.K6676R 048 0.137255 51 WCM80 Plasma 2 229890686 G A PID1 p.R139W 0 45 0.47619 63WCM80 Plasma 22 31953032 C T SFI1 p.R217W 0 50 0.066667 60 WCM80 Plasma22 38824050 C T KCNJ4 p.V30M 0 41 0.088889 45 WCM80 Plasma 3 66396808 GC SLC25A26 p.Q70H 0 54 0.333333 63 WCM80 Plasma 7 150500730 C T TMEM176Ap.T122M 0 50 0.369565 46 WCM80 Plasma 8 103663827 G A KLF10 p.P245S 0 320.09375 32 WCM80 Plasma 8 113267570 A T CSMD3 p.C3317S 0 36 0.534483 58WCM80 Plasma 8 77768306 T C ZFHX4 p.L3050S 0 40 0.188679 53 WCM80 Plasma9 101068579 C T GABBR2 p.A685T 0 41 0.233333 60 WCM80 Plasma 9 1053761 CT DMRT2 p.R189C 0 50 0.262295 61 WCM80 Plasma 1 168282103 G T TBX19p.G404C 0 104 0.255814 86 WCM80_Z1_1 Tissue 12 40852541 C A MUC19p.L1106I 0 177 0.320442 181 WCM80_Z1_1 Tissue 14 102606487 A G WDR20p.Y76C 0 86 0.22619 84 WCM80_Z1_1 Tissue 14 105353809 C A CEP170Bp.S1078Y 0 68 0.083333 72 WCM80_Z1_1 Tissue 15 92459662 G A SLCO3A1p.R207Q 0 103 0.22 100 WCM80_Z1_1 Tissue 17 11622752 G A DNAH9 p.R1885H0 206 0.242775 173 WCM80_Z1_1 Tissue 18 44036562 G A RNF165 p.R335Q 0223 0.053892 167 WCM80_Z1_1 Tissue 19 14866513 C T EMR2 p.D457N 0 710.393258 89 WCM80_Z1_1 Tissue 19 52619693 G C ZNF616 p.Q242E 0 620.402985 67 WCM80_Z1_1 Tissue 2 186678471 A G FSIP2 p.K6676R 0 700.359375 64 WCM80_Z1_1 Tissue 22 23230428 C G IGLL5 p.S65R 0 1510.089888 178 WCM80_Z1_1 Tissue 2 229890686 G A PID1 p.R139W 0 1520.29771 131 WCM80_Z1_1 Tissue 3 13679261 C T FBLN2 p.R1133C 0 1550.463087 149 WCM80_Z1_1 Tissue 3 88188671 G T ZNF654 p.E71* 0 620.297619 84 WCM80_Z1_1 Tissue 7 150500730 C T TMEM176A p.T122M 0 1420.363636 143 WCM80_Z1_1 Tissue 8 59059408 A G FAM110B p.T207A 0 1820.423529 170 WCM80_Z1_1 Tissue 5 109103259 G T MAN2A1 p.A287S 0 590.054054 74 WCM89 Plasma 7 148515125 G A EZH2 p.R357W 0 39 0.066667 60WCM89 Plasma 11 1099262 A G MUC2 p.E2414G 0 78 0.361702 94 WCM89_X1_1Tissue 1 204226501 G A PLEKHA6 p.R502* 0 65 0.173913 92 WCM89_X1_1Tissue 16 81397425 G T GAN p.E371D 0 55 0.446429 56 WCM89_X1_1 Tissue 1740485737 G A STAT3 p.R335W 0 52 0.380952 63 WCM89_X1_1 Tissue 2179588159 C T TTN p.R6906H 0 196 0.304659 279 WCM89_X1_1 Tissue 3129297265 G T PLXND1 p.D751E 0 57 0.066667 45 WCM89_X1_1 Tissue 3188242478 A C LPP p.E111A 0 79 0.234043 94 WCM89_X1_1 Tissue 3 77623761C T ROBO2 p.R695* 0 102 0.533333 120 WCM89_X1_1 Tissue 4 39343998 G ARFC1 p.R100W 0 74 0.117117 111 WCM89_X1_1 Tissue 5 114961344 A C TMED7p.F49C 0 113 0.235772 123 WCM89_X1_1 Tissue 5 98234026 A C CHD1 p.F433L0 77 0.38125 160 WCM89_X1_1 Tissue 8 10465652 T C RP1L1 p.T1986A 0 430.116279 43 WCM89_X1_1 Tissue 11 1099262 A G MUC2 p.E2414G 0 78 0.187564 WCM89_Z1_1 Tissue 11 3239964 G A MRGPRG p.P27L 0 94 0.327103 107WCM89_Z1_1 Tissue 1 204226501 G A PLEKHA6 p.R502* 0 65 0.140845 71WCM89_Z1_1 Tissue 15 40247912 G T EIF2AK4 p.G229V 0 54 0.073529 68WCM89_Z1_1 Tissue 15 93485061 A T CHD2 p.E234D 0 52 0.171053 76WCM89_Z1_1 Tissue 17 40485737 G A STAT3 p.R335W 0 52 0.259259 54WCM89_Z1_1 Tissue 18 77679334 A C PQLC1 p.F153C 0 60 0.076923 65WCM89_Z1_1 Tissue 2 179588159 C T TTN p.R6906H 0 196 0.210526 190WCM89_Z1_1 Tissue 3 188242478 A C LPP p.E111A 0 79 0.091954 87WCM89_Z1_1 Tissue 3 77623761 C T ROBO2 p.R695* 0 102 0.161905 105WCM89_Z1_1 Tissue 5 114961344 A C TMED7 p.F49C 0 113 0.229008 131WCM89_Z1_1 Tissue 5 98234026 A C CHD1 p.F433L 0 77 0.23 100 WCM89_Z1_1Tissue 6 29408478 C A OR10C1 p.S229Y 0 199 0.118812 202 WCM89_Z1_1Tissue 8 17132424 C G VPS37A p.S200* 0 104 0.265306 98 WCM89_Z1_1 Tissue10 120928786 C T PRDX3 p.R207Q 0 64 0.092308 65 WCM89_Z12_1 Tissue 1073475820 C T C10orf105 p.R92H 0 56 0.053333 75 WCM89_Z12_1 Tissue 11117063322 C G SIDT2 p.L672V 0 54 0.114754 61 WCM89_Z12_1 Tissue 1120417415 C A PRMT3 p.T156K 0 46 0.078947 38 WCM89_Z12_1 Tissue 1161053894 C T VWCE p.E145K 0 75 0.0625 80 WCM89_Z12_1 Tissue 1 20417103 GA PLA2G5 p.R112Q 0 188 0.055172 145 WCM89_Z12_1 Tissue 12 105464484 C TALDH1L2 p.V98M 0 257 0.149466 281 WCM89_Z12_1 Tissue 15 81592812 C AIL16 p.L1049I 0 48 0.071429 42 WCM89_Z12_1 Tissue 16 19083386 G T COQ7p.Q70H 0 234 0.052632 190 WCM89_Z12_1 Tissue 2 155099364 G T GALNT13p.C211F 0 130 0.258065 124 WCM89_Z12_1 Tissue 2 204036714 C T NBEAL1p.R2027* 0 56 0.085106 47 WCM89_Z12_1 Tissue 22 39631807 G A PDGFBp.R46C 0 142 0.074766 107 WCM89_Z12_1 Tissue 3 179525570 C T PEX5Lp.R523H 0 107 0.397059 68 WCM89_Z12_1 Tissue 3 49163577 G A LAMB2p.R723C 0 46 0.096774 31 WCM89_Z12_1 Tissue 3 52876927 G A TMEM110p.T223M 0 85 0.171875 64 WCM89_Z12_1 Tissue 5 77511916 C T AP3B1 p.R250Q0 68 0.06 50 WCM89_Z12_1 Tissue 6 35762930 T C CLPS p.K111R 0 850.135417 96 WCM89_Z12_1 Tissue 8 143546070 G A BAI1 p.V171M 0 35 0.12 50WCM89_Z12_1 Tissue 9 116858674 C T KIF12 p.R106H 0 59 0.090909 33WCM89_Z12_1 Tissue 9 134323084 G A PRRC2B p.R338H 0 36 0.28125 32WCM89_Z12_1 Tissue 10 124596398 G A CUZD1 p.R256W 0 58 0.09375 32WCM89_Z17_1 Tissue 10 21901358 C T MLLT10 p.R163* 0 46 0.069767 86WCM89_Z17_1 Tissue 10 35300798 C A CUL2 p.R695L 0 41 0.125 48WCM89_Z17_1 Tissue 10 63195969 C T TMEM26 p.V77I 0 112 0.054264 129WCM89_Z17_1 Tissue 11 1099262 A G MUC2 p.E2414G 0 78 0.193548 62WCM89_Z17_1 Tissue 11 64573749 C T MEN1 p.R340Q 0 80 0.076923 78WCM89_Z17_1 Tissue 11 64875352 G A VPS51 p.A195T 0 80 0.101695 59WCM89_Z17_1 Tissue 11 65771217 C T BANF1 p.R82* 0 95 0.058824 85WCM89_Z17_1 Tissue 11 76922284 G A MYO7A p.E2047K 0 102 0.065217 92WCM89_Z17_1 Tissue 11 773579 C T PDDC1 p.D100N 0 93 0.078125 64WCM89_Z17_1 Tissue 1 19439346 G A UBR4 p.R3825C 0 91 0.090909 66WCM89_Z17_1 Tissue 12 133381505 G A GOLGA3 p.S465L 0 87 0.064516 93WCM89_Z17_1 Tissue 1 228466650 G A OBSCN p.V2374M 0 121 0.081081 74WCM89_Z17_1 Tissue 12 49086916 C T CCNT1 p.R694Q 0 81 0.086957 46WCM89_Z17_1 Tissue 1 39322727 C T RRAGC p.E89K 0 41 0.1 50 WCM89_Z17_1Tissue 14 102471007 G A DYNC1H1 p.R1679Q 0 41 0.0625 48 WCM89_Z17_1Tissue 14 102807759 C T ZNF839 p.P560L 0 131 0.15 60 WCM89_Z17_1 Tissue14 23994842 G A ZFHX2 p.R1437C 0 65 0.081081 37 WCM89_Z17_1 Tissue 1593485061 A T CHD2 p.E234D 0 52 0.289474 38 WCM89_Z17_1 Tissue 1615880573 C T MYH11 p.G183R 0 52 0.066667 45 WCM89_Z17_1 Tissue 1630794825 G A ZNF629 p.S275L 0 60 0.082192 73 WCM89_Z17_1 Tissue 1631335782 G A ITGAM p.A689T 0 39 0.081081 37 WCM89_Z17_1 Tissue 163828768 C T CREBBP p.R625H 0 40 0.063158 95 WCM89_Z17_1 Tissue 1650325728 G A ADCY7 p.V153I 0 77 0.09375 64 WCM89_Z17_1 Tissue 1740485737 G A STAT3 p.R335W 0 52 0.114286 35 WCM89_Z17_1 Tissue 1742432404 G A FAM171A2 p.P393L 0 99 0.090909 66 WCM89_Z17_1 Tissue 1748678431 C T CACNA1G p.R1271W 0 91 0.075472 53 WCM89_Z17_1 Tissue 1760106978 C T MED13 p.E403K 0 83 0.077922 77 WCM89_Z17_1 Tissue 189535810 G A RALBP1 p.G615R 0 64 0.084746 59 WCM89_Z17_1 Tissue 1947863315 G A DHX34 p.V455I 0 172 0.051724 174 WCM89_Z17_1 Tissue 1955773980 C T HSPBP1 p.R359Q 0 64 0.073171 41 WCM89_Z17_1 Tissue 19795197 G A CLSTN1 p.P640L 0 114 0.064516 62 WCM89_Z17_1 Tissue 2229737569 C T AP1B1 p.V573I 0 122 0.08 75 WCM89_Z17_1 Tissue 2 38570463 GA ATL2 p.R104C 0 95 0.075949 79 WCM89_Z17_1 Tissue 3 129233312 G AIFT122 p.R1023H 0 81 0.057971 69 WCM89_Z17_1 Tissue 3 136240108 G ASTAG1 p.T208M 0 124 0.054054 111 WCM89_Z17_1 Tissue 3 49457751 C T AMTp.E122K 0 98 0.0625 80 WCM89_Z17_1 Tissue 4 151357970 C T LRBA p.R2287H0 42 0.06383 47 WCM89_Z17_1 Tissue 4 66356247 C T EPHA5 p.R417Q 0 310.058824 51 WCM89_Z17_1 Tissue 5 114961344 A C TMED7 p.F49C 0 1130.23622 127 WCM89_Z17_1 Tissue 5 131822527 G A IRF1 p.S125L 0 660.068182 44 WCM89_Z17_1 Tissue 5 16680190 C T MYO10 p.G1470R 0 940.070423 71 WCM89_Z17_1 Tissue 5 176700744 C T NSD1 p.R1861* 0 1410.056911 123 WCM89_Z17_1 Tissue 5 66462662 C T MAST4 p.S2552L 0 510.142857 35 WCM89_Z17_1 Tissue 5 98234026 A C CHD1 p.F433L 0 77 0.151515132 WCM89_Z17_1 Tissue 6 30866056 G A DDR1 p.R808H 0 77 0.05814 86WCM89_Z17_1 Tissue 6 90660782 G A BACH2 p.T348M 0 88 0.061728 81WCM89_Z17_1 Tissue 7 44294154 C T CAMK2B p.E110K 0 82 0.067568 74WCM89_Z17_1 Tissue 8 17132424 C G VPS37A p.S200* 0 104 0.263158 95WCM89_Z17_1 Tissue 9 122004459 G A BRINP1 p.R149C 0 71 0.061856 97WCM89_Z17_1 Tissue 9 139273671 G A SNAPC4 p.R870W 0 67 0.072727 55WCM89_Z17_1 Tissue X 118786978 C T 6-Sep p.D123N 0 61 0.072464 69WCM89_Z17_1 Tissue X 129354372 C T ZNF280C p.R493H 0 62 0.064103 78WCM89_Z17_1 Tissue X 132160520 G A USP26 p.R577* 0 56 0.076923 78WCM89_Z17_1 Tissue 10 45938974 G A ALOX5 p.R521H 0 90 0.073529 68WCM89_ZLN1_1 Tissue 10 49448448 C T FRMPD2 p.E219K 0 114 0.051471 136WCM89_ZLN1_1 Tissue 11 20070393 C T NAV2 p.P1364L 0 47 0.069767 43WCM89_ZLN1_1 Tissue 11 20398139 G A HTATIP2 p.R106H 0 119 0.063063 111WCM89_ZLN1_1 Tissue 1 146766162 C T CHD1L p.R860W 0 56 0.0625 48WCM89_ZLN1_1 Tissue 11 62751802 C T SLC22A6 p.V121M 0 104 0.054054 148WCM89_ZLN1_1 Tissue 1 33161326 C T SYNC p.V125M 0 85 0.062016 129WCM89_ZLN1_1 Tissue 1 43748569 G A C1orf210 p.R77C 0 46 0.085714 70WCM89_ZLN1_1 Tissue 1 46497194 C T MAST2 p.R1042C 0 47 0.136364 44WCM89_ZLN1_1 Tissue 15 93485061 A T CHD2 p.E234D 0 52 0.086957 46WCM89_ZLN1_1 Tissue 16 67293791 G A SLC9A5 p.R595H 0 72 0.078947 76WCM89_ZLN1_1 Tissue 17 29559809 C T NF1 p.R1136W 0 56 0.059322 118WCM89_ZLN1_1 Tissue 17 40485737 G A STAT3 p.R335W 0 52 0.232558 43WCM89_ZLN1_1 Tissue 19 2434447 G A LMNB2 p.R330W 0 43 0.096774 62WCM89_ZLN1_1 Tissue 19 45406310 G A TOMM40 p.V324M 0 131 0.055944 143WCM89_ZLN1_1 Tissue 2 179588159 C T TTN p.R6906H 0 196 0.159509 326WCM89_ZLN1_1 Tissue 3 119133444 G A ARHGAP31 p.E890K 0 53 0.073171 41WCM89_ZLN1_1 Tissue 4 74864001 G A CXCL5 p.T55M 0 53 0.114286 35WCM89_ZLN1_1 Tissue 4 83827705 C T THAP9 p.R169* 0 79 0.16 125WCM89_ZLN1_1 Tissue 5 114961344 A C TMED7 p.F49C 0 113 0.165775 187WCM89_ZLN1_1 Tissue 5 41911199 G A C5orf51 p.R135Q 0 38 0.066667 45WCM89_ZLN1_1 Tissue 5 98234026 A C CHD1 p.F433L 0 77 0.243243 148WCM89_ZLN1_1 Tissue 6 161139747 C T PEG p.R325C 0 96 0.068182 44WCM89_ZLN1_1 Tissue 6 7889769 G A TXNDC5 p.R260C 0 59 0.088235 68WCM89_ZLN1_1 Tissue 7 87436810 G A RUNDC3B p.R377Q 0 46 0.079365 63WCM89_ZLN1_1 Tissue 8 146033632 G A ZNF517 p.R444Q 0 44 0.116279 43WCM89_ZLN1_1 Tissue 8 1496891 C T DLGAP2 p.P11L 0 100 0.102564 78WCM89_ZLN1_1 Tissue 8 17132424 C G VPS37A p.S200* 0 104 0.120482 83WCM89_ZLN1_1 Tissue X 128922020 G A SASH3 p.E43K 0 82 0.050847 59WCM89_ZLN1_1 Tissue X 51640096 C T MAGED1 p.R449C 0 38 0.070175 57WCM89_ZLN1_1 Tissue 15 43748117 A C TP53BP1 p.S892A 0 42 0.081081 74WCM9 Plasma 17 26100253 G T NOS2 p.T498N 0 37 0.081081 37 WCM9 Plasma 2139817395 C T ERG p.W63* 0 41 0.073529 68 WCM9 Plasma 12 107386621 G ACRY1 p.Q569* 0 55 0.134615 104 WCM90 Plasma 19 38943561 C G RYR1 p.I449M0 33 0.289855 69 WCM90 Plasma 19 51021681 T G LRRC4B p.D430A 0 620.116505 103 WCM90 Plasma 2 74041237 C A C2orf78 p.P244Q 0 32 0.09589 73WCM90 Plasma 3 179605463 G T PEX5L p.A103D 0 60 0.050847 118 WCM90Plasma 3 56771308 G A ARHGEF3 p.R316W 0 31 0.150538 93 WCM90 Plasma 471509275 G A ENAM p.R711K 0 36 0.051282 78 WCM90 Plasma 5 89791499 G CPOLR3G p.E85Q 0 59 0.188679 106 WCM90 Plasma 6 47682185 G T GPR115p.D402Y 0 54 0.206522 92 WCM90 Plasma 7 44116185 C T POLM p.R253Q 0 360.133333 90 WCM90 Plasma 7 82580050 G A PCLO p.T3285M 0 34 0.255814 86WCM90 Plasma 10 126631331 G A ZRANB1 p.C90Y 0 59 0.185185 54 WCM90_Z1_1Tissue 10 7822090 C T KIN p.R102Q 0 146 0.233083 133 WCM90_Z1_1 Tissue11 100064331 G A CNTN5 p.W607* 0 77 0.104167 48 WCM90_Z1_1 Tissue 1152733118 C T KPRP p.R352C 0 65 0.421053 57 WCM90_Z1_1 Tissue 1165983717 T G PACS1 p.I263S 0 54 0.333333 54 WCM90_Z1_1 Tissue 12107386621 G A CRY1 p.Q569* 0 138 0.271186 177 WCM90_Z1_1 Tissue 1575120439 C T CPLX3 p.R77* 0 192 0.207254 193 WCM90_Z1_1 Tissue 1656500800 C G OGFOD1 p.P193R 0 31 0.285714 42 WCM90_Z1_1 Tissue 1657794796 G A KIFC3 p.R692W 0 37 0.166667 72 WCM90_Z1_1 Tissue 1687678040 G A JPH3 p.G187S 0 47 0.140351 114 WCM90_Z1_1 Tissue 1747696426 A T SPOP p.F133I 0 123 0.37931 116 WCM90_Z1_1 Tissue 2187366061 T A ZC3H15 p.D117E 0 44 0.204082 49 WCM90_Z1_1 Tissue 2221355014 C T THAP7 p.R100H 0 39 0.06 50 WCM90_Z1_1 Tissue 22 24237638 AG AP000350.4 p.V56A 0 53 0.4 60 WCM90_Z1_1 Tissue 2 74041237 C A C2orf78p.P244Q 0 34 0.2 50 WCM90_Z1_1 Tissue 3 134911606 C T EPHB1 p.R691W 0156 0.302469 162 WCM90_Z1_1 Tissue 3 179605463 G T PEX5L p.A103D 0 570.193182 88 WCM90_Z1_1 Tissue 3 56771308 G A ARHGEF3 p.R316W 0 43 0.37540 WCM90_Z1_1 Tissue 4 114436287 G T CAMK2D p.L253I 0 38 0.071429 42WCM90_Z1_1 Tissue 4 71509275 G A ENAM p.R711K 0 84 0.091667 120WCM90_Z1_1 Tissue 5 112175687 G A APC p.G1466R 0 137 0.2 80 WCM90_Z1_1Tissue 5 149357479 G T SLC26A2 p.M88I 0 53 0.405797 69 WCM90_Z1_1 Tissue5 156916172 T G ADAM19 p.N755H 0 79 0.416667 96 WCM90_Z1_1 Tissue 5169805776 C A KCNMB1 p.G170C 0 42 0.085714 35 WCM90_Z1_1 Tissue 612124055 G A HIVEP1 p.E1343K 0 67 0.076923 52 WCM90_Z1_1 Tissue 647682185 G T GPR115 p.D402Y 0.005587 179 0.769784 139 WCM90_Z1_1 Tissue7 24905026 C A OSBPL3 p.C203F 0 39 0.06383 47 WCM90_Z1_1 Tissue 744116185 C T POLM p.R253Q 0 112 0.333333 159 WCM90_Z1_1 Tissue 1152733118 C T KPRP p.R352C 0 65 0.101449 69 WCM90_Z19_1 Tissue 1155433205 C T OR4C6 p.T188M 0 68 0.166667 60 WCM90_Z19_1 Tissue 1165983717 T G PACS1 p.I263S 0 54 0.237288 59 WCM90_Z19_1 Tissue 12107386621 G A CRY1 p.Q569* 0 138 0.148936 141 WCM90_Z19_1 Tissue 1250749478 G T FAM186A p.D379E 0 39 0.085714 35 WCM90_Z19_1 Tissue 1470855215 C T SYNJ2BP p.R58Q 0 103 0.093023 86 WCM90_Z19_1 Tissue 1590026426 C A RHCG p.V132L 0 34 0.171429 35 WCM90_Z19_1 Tissue 1656500800 C G OGFOD1 p.P193R 0 31 0.090909 33 WCM90_Z19_1 Tissue 1747696426 A T SPOP p.F133I 0 123 0.12963 108 WCM90_Z19_1 Tissue 2224237638 A G AP000350.4 p.V56A 0 53 0.126984 63 WCM90_Z19_1 Tissue 2230415490 C G MTMR3 p.Y614* 0 154 0.10241 166 WCM90_Z19_1 Tissue 3134911606 C T EPHB1 p.R691W 0 156 0.155556 135 WCM90_Z19_1 Tissue 339374147 G T CCR8 p.V109L 0 46 0.0625 48 WCM90_Z19_1 Tissue 5 149357479G T SLC26A2 p.M88I 0 53 0.101124 89 WCM90_Z19_1 Tissue 5 156916172 T GADAM19 p.N755H 0 79 0.159091 132 WCM90_Z19_1 Tissue 5 89791499 G CPOLR3G p.E85Q 0 42 0.1 40 WCM90_Z19_1 Tissue 6 47682185 G T GPR115p.D402Y 0.005587 179 0.186207 145 WCM90_Z19_1 Tissue 7 137586116 G CCREB3L2 p.L343V 0 162 0.174497 149 WCM90_Z19_1 Tissue 1 152733118 C TKPRP p.R352C 0 65 0.588235 51 WCM90_Z21_1 Tissue 11 65983717 T G PACS1p.I263S 0 54 0.461538 52 WCM90_Z21_1 Tissue 12 107386621 G A CRY1p.Q569* 0 138 0.329268 246 WCM90_Z21_1 Tissue 13 113485800 C A ATP11Ap.Q445K 0 105 0.056604 53 WCM90_Z21_1 Tissue 1 6186793 C T CHD5 p.R1306Q0 51 0.066667 45 WCM90_Z21_1 Tissue 16 87678040 G A JPH3 p.G187S 0 470.181818 77 WCM90_Z21_1 Tissue 17 47696426 A T SPOP p.F133I 0 1230.41129 124 WCM90_Z21_1 Tissue 19 1272015 C T CIRBP p.S156L 0 370.083333 48 WCM90_Z21_1 Tissue 19 34900207 G T PDCD2L p.A160S 0 880.061856 97 WCM90_Z21_1 Tissue 20 44586302 C A ZNF335 p.A789S 0 1110.05641 195 WCM90_Z21_1 Tissue 2 187366061 T A ZC3H15 p.D117E 0 440.142857 70 WCM90_Z21_1 Tissue 22 24237638 A G AP000350.4 p.V56A 0 530.303571 56 WCM90_Z21_1 Tissue 2 61258865 G T PEX13 p.S135I 0 1520.078947 76 WCM90_Z21_1 Tissue 3 134911606 C T EPHB1 p.R691W 0 1560.461538 169 WCM90_Z21_1 Tissue 3 179605463 G T PEX5L p.A103D 0 570.373333 75 WCM90_Z21_1 Tissue 3 56771308 G A ARHGEF3 p.R316W 0 430.44186 43 WCM90_Z21_1 Tissue 4 71509275 G A ENAM p.R711K 0 84 0.08108174 WCM90_Z21_1 Tissue 5 112175687 G A APC p.G1466R 0 137 0.425532 47WCM90_Z21_1 Tissue 5 149357479 G T SLC26A2 p.M88I 0 53 0.243243 74WCM90_Z21_1 Tissue 5 156916172 T G ADAM19 p.N755H 0 79 0.594937 79WCM90_Z21_1 Tissue 5 89791499 G C POLR3G p.E85Q 0 42 0.772727 44WCM90_Z21_1 Tissue 6 47682185 G T GPR115 p.D402Y 0.005587 179 0.818182121 WCM90_Z21_1 Tissue 6 87966658 G T ZNF292 p.G1104V 0 120 0.053571 56WCM90_Z21_1 Tissue 7 44116185 C T POLM p.R253Q 0 112 0.292994 157WCM90_Z21_1 Tissue 8 11058363 G T XKR6 p.F162L 0 37 0.09375 32WCM90_Z21_1 Tissue 1 152733118 C T KPRP p.R352C 0 65 0.150685 73WCM90_Z25_1 Tissue 12 107386621 G A CRY1 p.Q569* 0 138 0.155405 148WCM90_Z25_1 Tissue 17 47696426 A T SPOP p.F133I 0 123 0.154472 123WCM90_Z25_1 Tissue 17 63189706 G T RGS9 p.M264I 0 42 0.078947 38WCM90_Z25_1 Tissue 2 179484486 C G TTN p.V13879L 0 52 0.121212 33WCM90_Z25_1 Tissue 3 134911606 C T EPHB1 p.R691W 0 156 0.147059 170WCM90_Z25_1 Tissue 3 20212228 G A SGOL1 p.R518C 0 147 0.116883 154WCM90_Z25_1 Tissue 3 56771308 G A ARHGEF3 p.R316W 0 43 0.153846 52WCM90_Z25_1 Tissue 5 112175687 G A APC p.G1466R 0 137 0.059322 118WCM90_Z25_1 Tissue 5 149357479 G T SLC26A2 p.M88I 0 53 0.166667 66WCM90_Z25_1 Tissue 5 156916172 T G ADAM19 p.N755H 0 79 0.145455 110WCM90_Z25_1 Tissue 5 89791499 G C POLR3G p.E85Q 0 42 0.131579 38WCM90_Z25_1 Tissue 6 47682185 G T GPR115 p.D402Y 0.005587 179 0.188525122 WCM90_Z25_1 Tissue 7 137586116 G C CREB3L2 p.L343V 0 162 0.163043184 WCM90_Z25_1 Tissue 10 7822090 C T KIN p.R102Q 0 146 0.158879 107WCM90_Z29_1 Tissue 1 152733118 C T KPRP p.R352C 0 65 0.285714 63WCM90_Z29_1 Tissue 11 65983717 T G PACS1 p.I263S 0 54 0.220339 59WCM90_Z29_1 Tissue 12 107386621 G A CRY1 p.Q569* 0 138 0.235772 123WCM90_Z29_1 Tissue 15 75120439 C T CPLX3 p.R77* 0 192 0.131868 182WCM90_Z29_1 Tissue 17 47696426 A T SPOP p.F133I 0 123 0.278846 104WCM90_Z29_1 Tissue 19 51021681 T G LRRC4B p.D430A 0 41 0.12 100WCM90_Z29_1 Tissue 22 24237638 A G AP000350.4 p.V56A 0 53 0.152174 46WCM90_Z29_1 Tissue 2 74041237 C A C2orf78 p.P244Q 0 34 0.125 32WCM90_Z29_1 Tissue 3 134911606 C T EPHB1 p.R691W 0 156 0.131944 144WCM90_Z29_1 Tissue 3 179605463 G T PEX5L p.A103D 0 57 0.15873 63WCM90_Z29_1 Tissue 3 56771308 G A ARHGEF3 p.R316W 0 43 0.25 32WCM90_Z29_1 Tissue 5 112175687 G A APC p.G1466R 0 137 0.177778 90WCM90_Z29_1 Tissue 5 149357479 G T SLC26A2 p.M88I 0 53 0.123077 65WCM90_Z29_1 Tissue 5 156916172 T G ADAM19 p.N755H 0 79 0.223404 94WCM90_Z29_1 Tissue 5 89791499 G C POLR3G p.E85Q 0 42 0.236842 38WCM90_Z29_1 Tissue 6 47682185 G T GPR115 p.D402Y 0.005587 179 0.325 120WCM90_Z29_1 Tissue 11 124189582 G T OR8D2 p.S171Y 0 88 0.652778 72WCM91_Z1_1 Tissue 1 205211032 C T TMCC2 p.Q203* 0 50 0.3 60 WCM91_Z1_1Tissue 12 110765737 C T ATP2A2 p.P337L 0 117 0.436782 174 WCM91_Z1_1Tissue 1 232596637 G A SIPA1L2 p.R1031* 0 193 0.587814 279 WCM91_Z1_1Tissue 1 248845130 C A OR14I1 p.G159V 0 131 0.588235 204 WCM91_Z1_1Tissue 12 95914845 C T USP44 p.A623T 0 199 0.117347 196 WCM91_Z1_1Tissue 13 111944474 G A ARHGEF7 p.G736D 0 44 0.71875 32 WCM91_Z1_1Tissue 14 50459539 C T C14orf182 p.V87I 0 36 0.170732 41 WCM91_Z1_1Tissue 15 45814220 T G SLC30A4 p.K111N 0 88 0.1 70 WCM91_Z1_1 Tissue 178401682 G A NEXN p.A476T 0 44 0.089552 67 WCM91_Z1_1 Tissue 19 13928586G A ZSWIM4 p.G457R 0 45 0.263158 57 WCM91_Z1_1 Tissue 19 39380581 G ASIRT2 p.R97C 0 104 0.181102 127 WCM91_Z1_1 Tissue 19 44610939 G T ZNF224p.C209F 0 128 0.404255 141 WCM91_Z1_1 Tissue 19 44833294 G A ZNF112p.P345L 0 80 0.37931 116 WCM91_Z1_1 Tissue 19 50156923 C G SCAF1p.P1093A 0 65 0.112676 71 WCM91_Z1_1 Tissue 2 10140761 T G GRHL1 p.S595A0 81 0.16129 93 WCM91_Z1_1 Tissue 21 45999762 C T KRTAP10-5 p.A232T 0124 0.585714 140 WCM91_Z1_1 Tissue 2 160239129 C T BAZ2B p.E1316K 0 1140.192308 104 WCM91_Z1_1 Tissue 2 161025757 A G ITGB6 p.F328S 0 600.133333 60 WCM91_Z1_1 Tissue 2 80782980 A G CTNNA2 p.E568G 0 1490.30303 198 WCM91_Z1_1 Tissue 3 164905781 G T SLITRK3 p.H946Q 0 940.484536 97 WCM91_Z1_1 Tissue 6 10756717 A C TMEM14B p.K104T 0 179 0.2195 WCM91_Z1_1 Tissue 6 39688562 T G KIF6 p.K31T 0 36 0.150943 53WCM91_Z1_1 Tissue 7 107417117 T G SLC26A3 p.T517P 0 38 0.181818 44WCM91_Z1_1 Tissue X 40464879 A T ATP6AP2 p.M309L 0 42 0.597938 97WCM91_Z1_1 Tissue 11 10503668 G A AMPD3 p.R171Q 0 184 0.257862 159WCM9_X1_1 Tissue 11 75438598 C T MOGAT2 p.S130L 0 131 0.066667 120WCM9_X1_1 Tissue 12 18872552 G T PLCZ1 p.Q128K 0 37 0.238806 67WCM9_X1_1 Tissue 1 27332698 G A FAM46B p.R339C 0 85 0.134328 67WCM9_X1_1 Tissue 14 21360033 G A RNASE3 p.R63H 0 113 0.181818 110WCM9_X1_1 Tissue 14 35872358 T C NFKBIA p.N182S 0 52 0.28 100 WCM9_X1_1Tissue 14 75513676 G A MLH3 p.R895C 0 77 0.067308 104 WCM9_X1_1 Tissue15 81585194 G A IL16 p.R573Q 0 37 0.111111 36 WCM9_X1_1 Tissue 1618828765 G T SMG1 p.H3308N 0 68 0.157895 76 WCM9_X1_1 Tissue 16 23721844C T ERN2 p.V76I 0 41 0.283333 60 WCM9_X1_1 Tissue 17 73239148 G A GGA3p.S175F 0 83 0.071429 70 WCM9_X1_1 Tissue 19 17396343 C T ANKLE1 p.R494W0 113 0.311475 122 WCM9_X1_1 Tissue 20 13260377 C T ISM1 p.R159W 0 450.241935 62 WCM9_X1_1 Tissue 3 50154781 G A RBM5 p.R764Q 0 69 0.23880667 WCM9_X1_1 Tissue 5 140181632 G A PCDHA3 p.D284N 0 90 0.304688 128WCM9_X1_1 Tissue 5 154278847 G C GEMIN5 p.A1013G 0 86 0.158879 107WCM9_X1_1 Tissue 1 100214293 C T FRRS1 p.C11Y 0 63 0.081081 37 WCM9_Z3-1Tissue 11 10503668 G A AMPD3 p.R171Q 0 184 0.261538 65 WCM9_Z3-1 Tissue11 119181152 G T MCAM p.S606R 0 143 0.096386 83 WCM9_Z3-1 Tissue 12104373677 C A TDG p.P79T 0 77 0.257143 35 WCM9_Z3-1 Tissue 12 13716863 GC GRIN2B p.D1103E 0 32 0.143939 264 WCM9_Z3-1 Tissue 1 27332698 G AFAM46B p.R339C 0 85 0.230769 65 WCM9_Z3-1 Tissue 14 21360033 G A RNASE3p.R63H 0 113 0.268657 134 WCM9_Z3-1 Tissue 15 23686113 C G GOLGA6L2p.Q503H 0 36 0.148456 842 WCM9_Z3-1 Tissue 16 3066004 G A CLDN6 p.Q7* 0162 0.052632 133 WCM9_Z3-1 Tissue 16 71660273 C A MARVELD3 p.S47R 0 320.058824 51 WCM9_Z3-1 Tissue 17 1686445 C A SMYD4 p.W715C 0 200 0.1 50WCM9_Z3-1 Tissue 17 39261693 A T KRTAP4-9 p.D18V 0 39 0.083333 48WCM9_Z3-1 Tissue 17 80333060 C T UTS2R p.P287L 0 83 0.232143 56WCM9_Z3-1 Tissue 19 17396343 C T ANKLE1 p.R494W 0 113 0.292308 65WCM9_Z3-1 Tissue 19 44057183 G A XRCC1 p.A221V 0 78 0.06 50 WCM9_Z3-1Tissue 19 48519277 G T ELSPBP1 p.W112C 0 33 0.061224 49 WCM9_Z3-1 Tissue19 49969496 C T ALDH16A1 p.R632W 0 107 0.2 45 WCM9_Z3-1 Tissue 1951826981 G A IGLON5 p.G75D 0 46 0.068182 44 WCM9_Z3-1 Tissue 20 13260377C T ISM1 p.R159W 0 45 0.25974 77 WCM9_Z3-1 Tissue 2 230456343 G A DNERp.P180S 0 94 0.202632 380 WCM9_Z3-1 Tissue 5 149511596 G A PDGFRBp.R397W 0 65 0.21875 128 WCM9_Z3-1 Tissue 5 154278847 G C GEMIN5p.A1013G 0 86 0.307692 104 WCM9_Z3-1 Tissue 7 107708565 C T LAMB4p.C781Y 0 86 0.072115 208 WCM9_Z3-1 Tissue 7 76828504 G T FGL2 p.R203S 039 0.180147 272 WCM9_Z3-1 Tissue 8 116631420 C T TRPS1 p.G289D 0 1100.073171 82 WCM9_Z3-1 Tissue 9 34725069 T A FAM205A p.E723V 0 55 0.187548 WCM9_Z3-1 Tissue X 73962078 G A KIAA2022 p.R772C 0 33 0.119658 117WCM9_Z3-1 Tissue *denotes a nonsense mutation

(vii) Similarity Measure Based on Copy Number Profiles

For each patient, the somatic copy number aberration (SCNA) profiles oftumor tissues and cfDNA samples were compared (Table 3). Comparison wasperformed using an ad-hoc notion of similarity, which exploits tumorcontent corrected SCNA profiles (FIG. 1B) and measures the percentage ofconcordant aberration signal. Specifically, given a sample P and asample T, the algorithm computes the following steps:

1. SCNA profile signal of sample P is centered around the P mean signal;

2. SCNA profile signal of sample T is centered around the T mean signal;

3. SCNA signals of P and T samples are synchronized around their mediandifference to avoid the presence of systematic signal shifts due totechnical or processing bias. Specifically, SCNAs signal P is normalizedas P=P −median(P−T);

4. a measure of loss similarity S_(loss) is obtained by measuring thefraction of genes having signal below the detection threshold −THR inboth P and T profiles over the total number of genes having a signalbelow the detection threshold −THR in at least one of the two samples;

5. a measure of gain similarity S_(gain) is obtained by measuring thefraction of genes having signal above the detection threshold THR inboth P and T profiles over the total number of genes having a signalabove the detection threshold THR in at least one of the two samples;

6. A global similarity measure is obtained as S=(S_(loss)+S_(gain))/2.

A model with 19,027 genes was here considered along with a detectionthreshold THR equal to 0.3.

f. Similarity Measure Based on SNV Profiles

For each patient and each plasma and tumor tissue sample's pair privateand shared somatic SNVs were then compiled. For each patient, aninclusion matrix considering all plasma-tissue and tissue-tissue pairswas computed, including non-synonymous SNVs only. Specifically, for eachpair (P1, P2) of samples the inclusion matrix reports both the fractionof mutations detected in P1 that are also detected in P2 and thefraction of mutations detected in P2 that are also detected in P1.

g. Estimation of Clonality Divergence

Non-discretized estimations of allele-specific copy number analysis(Table 3) were used to calculate the Clonality Divergence Index. Foreach sample and each genomic segment, the Euclidean difference betweenthe estimated raw allele-specific copy number and the closest expectedclonal allele-specific copy number was assessed. The average of theminimum distances is the Clonality Divergence Index. Formally,considering a sample P and segment S and its estimated allele-specificcopy number coordinates (cnA, cnB), in a Euclidean space with can andcnB real numbers, the value was compute:

$D_{S} = {\min\limits_{e \in C}\overset{\_}{ep}}$

Where ep is the Euclidian distance of p=(cnA, cnB) and a point in C={(a,b)|a, b∈M} with M equal to the least integer greater than or equal tothe maximum raw cnA or cnB estimated across all P segments. TheClonality Divergence index of P is the mean of all Ds computed for allsegments S of P. A sample with all and only segments with perfectinteger (cnA, cnB) would have a Clonality Divergence Index equal tozero.

h. Whole Genome Bisulfite Sequencing (WGBS) Data Generation andProcessing

5 ng of cfDNA and 100 ng of germline DNA were sonicated using a CovarisS220 to approximately 180-220 bp (Covaris, Woburn, Mass.) and bisulfiteconverted using EZ DNA Methylation-Gold Kit (cat # D5005, Zymo ResearchCorporation, Irvine, Calif.). The single-stranded DNA obtained wasprocessed for library construction using the Accel-NGS@Methyl-seq DNALibrary kit (cat #36024) as per manufacturer instructions (SwiftBioSciences, Ann Arbor, Mich.). Briefly, truncated adapter sequenceswere incorporated to the single-stranded DNA in a template-independentreaction through sequential steps using the Adaptase™ module. DNA wasthen enriched using PCR with primers compatible with Illuminasequencing, 9 cycles for cfDNA and 6 cycles for genomic DNA. Thelibraries were clustered at 12 pM on a pair end read flow cell andsequenced for 125 cycles on Illumina HiSeq 2500 or 4000. Primaryprocessing of sequencing images was done using Illumina's Real TimeAnalysis software (RTA). CASAVA 1.8.2 software was then used todemultiplex samples and generate raw reads and respective qualityscores. The WGBS raw data was quality filtered and adapter trimmed usingFlexbar with parameters -ao 6, -m 21, -at 2. Reads were aligned tounmasked Human genome build GRCh37/hg19 and methylation calls weregenerated with Bismark (Krueger and Andrews (2011) Bioinformatics27:1571-1572) as described in the data analysis section of theEpigenomics Core in-house bisulfite sequencing analysis pipeline(Garrett-Bakelman et al. (2015) J Vis Exp:e52246). The averageconversion rate in WGBS samples is 99.6%, the average CpG coverage is14.3 and the average mapping efficiency is 76% (Table 5). For plasmarelated analysis, Only CpG sites covered by at least 10 reads and readin at least 10% of the study samples were considered for downstreamanalysis. For each sample, the percentage of methylation per site (betavalue) was computed. ctDNA fraction was estimated by PAMES, using 10hyper-methylated prostate specific CpG islands (Benelli, Romagnoli, andDemichelis (2018) Bioinformatics 34:1642-1649). CpG wise differentialmethylation analysis (CRPC-NE versus CRPC-Adeno) was performed by AreaUnder the Curve (AUC) analysis. Hyper- and hypo-methylated sites wereidentified as those sites demonstrating AUC=1 and AUC=0, respectively.Genomic annotation of methylation sites was performed by the toolannotatePeaks included in the HOMER package16 (Table 6).

TABLE 5 Aligner sequencing statistics for WGBS samples Mean avg. mappingCpG conversion efficiency Sample Type cov. rate (%) (%) Mapped_readsWCM0 Plasma 13.64 99.62 76.90% 767980146 WCM0 Germline 13.64 99.6276.90% 583747822 WCM14 Plasma 14.06 99.62 76.00% 679594352 WCM14Germline 14.06 99.62 76.00% 633594624 WCM78 Plasma 15.29 99.43 80.20%615261868 WCM78 Germline 13.4  99.63 75.50% 543578974 WCM90 Plasma 14.4799.47 79.10% 626545886 WCM90 Germline 14.18 99.62 76.80% 658399870WCM119 Plasma 14.58 99.52 78.40% 669516040 WCM119 Germline 14.17 99.6375.90% 634191076 WCM154 Plasma 14.44 99.57 79.50% 638284428 WCM154Germline 13.66 99.63 75.30% 556590598 WCM155 Plasma 15.08 99.6  72.90%813407242 WCM155 Germline 14.97 99.71 71.20% 748223332 WCM161 Plasma15.12 99.52 71.00% 714276482 WCM161 Germline 14.9  99.68 72.40%758044212 WCM163 Plasma 14.51 99.55 78.50% 626607384 WCM163 Germline14.05 99.62 76.00% 624074488 WCM207 Plasma 14.39 99.56 79.60% 644873354WCM207 Germline 14.22 99.58 76.20% 642641686 WCM677 Plasma 14    99.5478.70% 555277164 WCM677 Germline 13.94 99.6  76.30% 616407358

TABLE 6 Methylation sites included in the NEPC feature score Methylationstatus Nearest Start End (NE vs Distance Promoter chr (hg19) (hg19)Adeno) Annotation to TSS ID chr1 241206098 241206097 hyper intron −89475NR_036069 (NM_001282773, intron 3 of 15) chr18 47258089 47258088 hyperIntergenic 82163 NM_006111 chr21 32546326 32546325 hyper intron −135530NM_001099219 (NM_003253, intron 16 of 28) chr5 1548487 1548486 hyperIntergenic −24410 NM_024830 chr5 71146894 71146893 hyper Intergenic131903 NM_004291 chr5 142194123 142194122 hyper intron 43830 NM_015071(NM_015071, intron 1 of 22) chr7 7799018 7799017 hyper intron −40779NM_002947 (NM_001302350, intron 3 of 4) chr7 127841628 127841627 hyperIntergenic −6298 NR_029596 chr8 53499560 53499559 hyper Intergenic−21538 NM_207413 chr8 73479990 73479989 hyper exon 30363 NM_004770(NM_004770, exon 2 of 3) chr8 73849054 73849053 hyper exon −72044NM_003218 (NM_004770, exon 3 of 3) chr8 140727998 140727997 hyperIntergenic −12698 NR_104210 chr8 141994084 141994083 hyper intron 17329NM_001199649 (NM_153831, intron 1 of 31) chr8 142367954 142367953 hyperexon 9412 NM_005293 (NM_005293, exon 2 of 2) chr8 143395944 143395943hyper intron 88667 NM_145003 (NM_001291931, intron 6 of 10) chr936748433 36748432 hyper Intergenic 75164 NR_039686 chr9 3843731438437313 hyper Intergenic −12869 NM_001007563 chr9 93792388 93792387hyper Intergenic 45027 NR_033912 chr9 133769512 133769511 hyper intron2688 NM198180 (NM_198180, intron 2 of 2) chr9 138719304 138719303 hyperexon 79702 NM_015447 (NM_015447, exon 8 of 17) chr1 202039153 202039152hypo Intergenic −52877 NM_004767 chr14 100039425 100039424 hypo intron31303 NM_001144995 (NM_001144995, intron 1 of 5) chr18 8660098 8660097hypo Intergenic 47522 NR_120598 chr18 14917016 14917015 hypo Intergenic−29251 NR_104164 chr18 25442246 25442245 hypo Intergenic 174304NM_001308176 chr2 89530057 89530056 hypo Intergenic 418172 NR_039635chr20 20421462 20421461 hypo intron 72696 NM_002196 (NM_020343, intron37 of 39) chr20 21563921 21563920 hypo intron 13258 NR_109880(NR_109880, intron 1 of 3) chr21 46885392 46885391 hypo intron 9967NM_130444 (NM_130444, intron 1 of 41) chr3 193490472 193490471 hypoIntergenic −145350 NR_046634 chr5 36521979 36521978 hypo Intergenic−84479 NM_001289940 chr5 39390555 39390554 hypo exon −25899 NM_001737(NM_001343, exon 5 of 15) chr5 168573593 16857359 hypo intron 117106NR_030311 (NM_001271946, intron 4 of 35) chr7 2006579 2006578 hypointron −26392 NM_001304525 (NM_001304523, intron 14 of 17) chr7129912398 129912397 hypo intron 5694 NM_001869 (NM_001869, intron 4 of10) chr8 61990390 61990389 hypo Intergenic −110082 NR_034003 chr869087227 69087226 hypo intron −155731 NM_052958 (NM_024870, intron 35 of39) chr8 133070961 133070960 hypo intron 667 NM_001080399 (NM_001080399,intron 1 of 13) chr8 141458926 141458925 hypo intron 8936 NM_001160372(NM_031466, intron 2 of 22) chr9 134913161 134913163 hypo intron 42111NM_001253881 (NM_001253881, intron 2 of 6) Gene chr Gene Name Gene AliasGene Description Type chr1 MIR3123 mir-3123 microRNA 3123 ncRNA chr18ACAA2 DSAEC acetyl-CoA protein- acyltransferase 2 coding chr21 KRTAP19-8— keratin associated protein- protein 19-8 coding chr5 LPCAT1 AYTL2|lysophosphatidylcholine protein- PFAAP3| acyltransferase 1 coding lpcatchr5 CARTPT CART CART protein- prepropeptide coding chr5 ARHGAP26GRAF|GRAF1| Rho GTPase protein- OPHN1L|OPHN1L1 activating protein coding26 chr7 RPA3 REPA3 replication protein protein- A3 coding chr7 MIR129-1MIR-129b|MIRN129- microRNA 129-1 ncRNA 1|mir-129-1 chr8 FAM150A UNQ9433family with protein- sequence coding similarity 150, member A chr8 KCNB2KV2.2 potassium protein- channel, voltage coding gated Shab relatedsubfamily B, member 2 chr8 TERF1 PIN2|TRBF1| telomeric repeat protein-TRF|TRF1|hTRF1- binding factor coding AS|t-TRF1 (NIMA- interacting) 1chr8 KCNK9 K2p9.1|KT3.2| potassium protein- TASK-3|TASK3 channel, twopore coding domain subfamily K, member 9 chr8 PTK2 FADK|FAK| proteintyrosine protein- FAK1|FRNK| kinase 2 coding PPP1R71|p125FAK| pp125FAKchr8 GPR20 — G protein-coupled protein- receptor 20 coding chr8 TSNARE1— t-SNARE domain protein- containing 1 coding chr9 MIR4475 — microRNA4475 ncRNA chr9 IGFBPL1 IGFBP-RP4| insulin like protein- IGFBPRP4|growth factor coding bA113O24.1 binding protein- like 1 chr9LOC100129316 — uncharacterized ncRNA LOC100129316 chr9 QRFP 26RFa|P518pyroglutamylated protein- RFamide peptide coding chr9 CAMSAP1 PRO2405|calmodulin protein- bA100C15.1 regulated coding spectrin- associatedprotein 1 chr1 GPR37L1 ET(B)R-LP-2| G protein-coupled protein- ETBR-LP-2receptor 37 like 1 coding chr14 CCDC85C — coiled-coil protein- domaincoding containing 85C chr18 GACAT2 MTCL1-AS1| gastric cancer ncRNAMTCL1ASI associated transcript 2 (non- protein coding) chr18 LINC01443 —long intergenic ncRNA non-protein coding RNA 1443 chr18 CDH2 CD325|CDHN|cadherin 2, type 1, protein- CDw325|NCAD N-cadherin coding (neuronal)chr2 MIR4436A mir-4436a microRNA 4436a ncRNA chr20 INSM1 IA-1|IA1insulinoma- protein- associated 1 coding chr20 LOC101929625 —uncharacterized ncRNA LOC101929625 chr21 COL18A1 KNO|KNO1|KS collagen,type protein- XVIII, alpha 1 coding chr3 OPA1-AS1 — OPA1 antisense ncRNARNA 1 chr5 SLC1A3 EA6|EAAT1| solute carrier protein- GLAST|GLAST1 family1 (glial coding high affinity glutamate transporter), member 3 chr5 C9ARMD15|C9D complement protein- component 9 coding chr5 MIR585MIRN585|hsa-mir- microRNA 585 ncRNA 585|mir-585 chr7 MAD1L1 MAD1|PIG9|MAD 1 mitotic protein- IP53I9|TXBP181 arrest deficient- coding like 1(yeast) chr7 CPA2 — carboxypeptidase protein- A2 (pancreatic) codingchr8 LOC100130298 — hCG1816373-like ncRNA chr8 C8orf34 VEST-1|VEST1chromosome 8 protein- open reading coding frame 34 chr8 OC90 PLA2Lotoconin 90 protein- coding chr8 TRAPPC9 IBP|IKBKBBP| traffickingprotein protein- MRT13|NIBP| particle complex 9 coding T1|TRS120 chr9MED27 CRAP34|CRSP34| mediator complex protein- CRSP8|TRAP37 subunit 27coding

i. Concordance of Differential Methylation in Matched Plasma and TissueSamples

Differentially methylated regions (DMRs) were nominated usingRocker-meth. Starting from published enhanced reduced representationbisulfate sequencing of solid tumor biopsy samples and healthy prostatetissues (eRRBS-Sequencing (Beltran et al. (2016) Nat Med 22:298-305; Linet al. (2013) Neoplasia 15:373-383)), two orthogonal differentialmethylation analysis were performed using default parameters values withthe exception of na_threshold set to 0.3. First, DMRs between primaryprostate cancer tissues (test, n=7) and normal prostatic tissue(control, n=7), (PCa|NT) were identified. Second, CRPC-NE (test, n=10)was compared to CRPC-Adeno (control, n=18), obtaining a set of DMRswhich reflects methylation changes upon transdifferentiation(CRPC-NE|CRPC-Adeno). FDR of 0.01, an absolute average Beta differenceof 20 between test and control and the presence of at least 6 detectedCpG sites inside the region were applied as filters. Shared DMRs wereisolated using bedtools -multiiterclust (Quinlan (2014) Curr ProtocBioinformatics 47:11.12.1-34) and discarded. To capture single samplealterations of DNA methylation, z-scores for each DMR in each pair oftissue-plasma matched samples were computed by Rocker-meth using normalprostatic tissue as reference. To control for potential sources of noisedue to non-tumoral cfDNA, the methylome of peripheral blood mono-nuclearcells (PBMC) of all 11 patients was also profiled using WGBS sequencing.For both DMR sets the z-scores detected across PBMC samples wereevaluated and the DMRs that consistently deviated (abs(z-score)>5) fromthe reference in more than 80% (at least 9 out of 11) of PBMC sampleswere excluded. A total of 7,606 and 3,843 DMRs were obtained for PCa|NTand CRPC-NE|CRPC-Adeno, respectively (Table 4). To maximize thecompatibility of different assays, only CpG sites detected in at leastmore than half of plasma samples (ctDNA and PBMC) were retained insingle sample z-score computation, excluding sites that were detectedonly in eRRBS tissue samples. Furthermore, all DMRs containing less than6 detected CpG sites in WGBS samples or with an undetectable signal inone or more WGBS plasma samples were excluded from pairwisetissue-plasma analysis and DMR score computation to ensure consistencybetween samples.

j. Integration of Plasma Methylomes from an Independent CRPC Cohort

To evaluate the robustness of the findings, a published cohort of cfDNAmethylomes of patients was analyzed with CRPC treated with abirateroneand prednisone (Gordeviĉius et al. (2018) Clin Cancer Res 24:3317-3324)generated with the HM450 array, including only end of treatment (EoT)time-point data to maximize the similarity in disease state and clinicalhistory. Using the previously defined set of CRPC-NE|CRPC-Adeno DMRs,single sample z-scores were computed for EoT time-points (using normaltissue samples from TCGA-PRAD as reference (Network (2015) Cell163:1011-1025)). In order to obtain a comparable set of samples, onlysamples with TC (Benelli, Romagnoli, and Demichelis (2018)Bioinformatics 34:1642-1649) above or equal to 10% were retained in theanalysis using a threshold similar to prior WES ctDNA studies(Adalsteinsson et al. (2017) Nat Commun 8:1324).

k. Differentially Methylated Regions

Given methylation values for each CpG site in a control and a test setof samples, the following procedure was applied: i) for each detectedsite, the area under the receiver operator characteristics was computed(AUROC), evaluating the segregation between groups based solely ontarget CpG signal. ii) Sequential AUROC values were divided intosegments with a common methylation status (hyper-methylated, neutral orhypo-methylated) following a three-state heterogeneous shifting levelmodel. iii) Significance of differential methylation between control andtest group was assessed for each DMR with WMW-test on average Betavalues, and p-values are corrected for multiple hypothesis testing withstandard BH procedure.

l. Neuroendocrine Prostate Cancer (NEPC) Score

The NEPC score includes genomic and methylation-based features. Genomicfeatures include RB1 deletion or mutation, TP53 deletion or mutation, ARfocal gain or mutation, and CYLD deletion. TP53, RB1 and CYLD genomicbased features for the NEPC feature score are set to one for a specificsample if the aberration is present; AR genomic feature is instead setto one for a specific sample in case of absence of aberrations.Methylation based signal includes two components based on top 20 hypo-and 20 hyper-methylated sites based on previous tissue analysis (Table6). Briefly, differentially methylated sites from Beltran et al. (Table7, from Beltran et al. (2016) Nat Med 22:298-305) were ranked by FDR andby beta difference (CRPC-NE vs CRPC-Adeno) and retained only those sitesfound in WGBS data. To avoid redundant signal, the top-ranking one wasretained if sites were within 10 Kp from each other. Next, to havecomparable methylation levels from tissue and plasma samples, a puritycorrection of M-values was applied using PAMES. Then, for each tophyper- and hypo-methylated site, the threshold that best discriminatedbetween CRPC-Adeno and CRPC-NE tissue samples was identified by Receiveroperating characteristic (ROC) curve analysis. Last, plasma methylationdata were dichotomized as follows: for each plasma sample, methylationfeature score is equal to 1 if the majority of sites show methylationlevel above (hyper) or below (hypo) the site specific tissue-basedthreshold. The NEPC feature score was computed for a specific sample bycounting the number of features set to one and normalizing by the numberof available features for that sample. Features with no call were set toNA and were not considered in the score computation.

m. Statistical Analysis

Association of plasma genomics and binary clinical variables wasperformed using two-tailed Wilcoxon-Mann-Whitney test with significancelevel set at 5%. Association of plasma genomics and continuous clinicalvariables was performed using Pearson correlation statistics withsignificance level set at 5%. Statistical comparison of genomicvariables across sample's classes was performed using two-tailedWilcoxon-Mann-Whitney test with significance level set at 5%. Univariateoverall survival and progression-free survival analyses were performedusing the Kaplan-Meier estimator (log-rank test). Multivariate overalland progression-free survival analyses were performed using aproportional hazard model with stepwise model selection by Akaikeinformation criterion using forward and backward directions.

n. Study Approval

This study was approved by the institutional review board (WCM IRB#1305013903, #1210013164) and written informed consent was obtained fromparticipants prior to inclusion in the study.

All BAM files generated for this study and associated sample informationare described in Tables 2 and 8. and accessible through dbGaP(phs001752.v1.p1): available on the World Wide Web atncbi.nlm.nih.gov/projects/gap/cgibin/study.cgi?study_id=phs001752.v1.p1.

Example 2: Identification of Genomic and Epigenomic Features of CRPC-NE

It was hypothesized that while tumors do acquire specific CRPC-NEchanges (predominantly epigenetic) during the process of lineageplasticity, early resistant or aggressive prostate cancer clones (suchas those already harboring loss of RB1 and TP53) may also gain clonaldominance during CRPC-NE transformation and may be early selectedfacilitators of transdifferentiation. While metastatic lesions inprostate cancer may harbor evidence of subclonal heterogeneity acrosssites potentially due to metastasis-to-metastasis seeding as observed inprior studies (Gundem et al. (2015) Nature 520:353-357), it waspredicted that tumors would become less heterogeneous as patientsprogress towards CRPC-NE in later stages of the disease (as seen inrapid autopsy studies (Kumar et al. (2016) Nat Med 22:369-378)). To testthis hypothesis, tumor DNA detectable in the circulation of patients wasstudied with CRPC-NE and CRPC-Adeno and compared their genomic andepigenomic profiles with patient-matched tumor biopsies.

In addition to using circulating tumor DNA (ctDNA) as a tool to studyheterogeneity, the potential utility of this approach as a noninvasivetool for the detection of CRPC-NE was explored by querying specificgenomic and epigenomic changes seen in CRPC-NE tumors (Abida et al.(2019) Proc Natl Acad Sci USA 116:11428-11436; Aggarwal et al. (2018) JClin Oncol JCO201777 6880; Beltran et al. (2016) Nat Med 22:298-305) inthe circulation of biopsy-confirmed patients. A circulating biomarkerfor CRPC-NE has potential clinical implications that can lead to futureavoidance of invasive biopsy for patients (the current standard forCRPC-NE diagnosis). Furthermore, since there is a spectrum ofhistologies even within CRPC-NE and as patients progress fromadenocarcinoma to CRPC-NE, with mixed adenocarcinoma-neuroendocrinemorphologies and hybrid tumors with overlapping features sometimesobserved (Beltran et al. (2019) Clin Cancer Res 25:6916-6924; Epstein etal. (2014) Am J Surg Pathol 38:756-767), identifying molecular featurescould provide additional information above or complementary to a tumorbiopsy. Noninvasive detection of molecular features of CRPC-NE cantherefore lead to a more refined subclassification and detect featuresin patients at high risk for transformation even without CRPC-NEhistology, paving the way for early intervention treatment strategies.

Plasma blood samples and matched metastatic tumor biopsies were obtainedfrom sixty-two men with metastatic prostate cancer (10 hormone naivemetastatic prostate adenocarcinoma (mPCA), 35 castration resistantprostate adenocarcinoma (CRPC-Adeno) and 17 CRPC-NE) classifiedhistologically using published criteria (Epstein et al. (2014) Am J SurgPathol 38:756-767). Clinical features are summarized in Table 9 and FIG.1A. Twenty-four of these individuals had multiple tissue or plasmatime-points, for a total of 69 plasma samples and 98 metastatic tissues(Tables 2, and 9-11). Metastatic sites of patients at the time ofspecimen collection included bone (84%), lymph node (52%), liver (32%),lung (16%), brain (6%). Overall patients in this study had highmetastatic burden, including 50% with visceral metastases and >45% ofpatients with >6 bone metastases. The median number of prior therapiesfor CRPC was two (range 0-9); 42.8% patients received prior abirateroneor enzalutamide, and 65.7% received prior cytotoxic chemotherapy. Themedian time between prior therapy progression and blood draw was 3.2months (range 1.1-9.1). Median progression free survival on next line ofsystemic therapy (after blood/tissue collection) for CRPC patients was4.1 months (4.3 months CRPC-Adeno, 4.0 months CRPC-NE), and medianoverall survival was 11.0 months (12.0 months CRPC-Adeno, 6.0 monthsCRPC-NE).

TABLE 9 Patient demographics Overall CRPC-Adeno CRPC-NE (n = 62) (n =35) (n = 17) Age at diagnosis of PCA, years 65 (50-90) 62 (50-90) 68(54-90) Median (range) Prostatectomy, n (%) 21 (33.9) 15 (42.9) 5 (29.4)Radical radiotherapy, n (%) 24 (38.7) 12 (34.3) 7 (41.2) Gleason sum atdiagnosis, n (%) ≤7 21 (38.9) 11 (32.4) 6 (50) ≥8 33 (61.1) 23 (67.6) 6(50) Unknown/missing  8  1 5 Classification at plasma collection, n (%)CRPC-Adeno 35 (56.5) 35 (100) 0 (0) CRPC-NE 17 (27.4) 0 (0) 17 (100) HNmet PCA 10 (16.1) 0 (0) 0 (0) Sites of metastases, n (%) Bone 52 (83.9)30 (85.7) 12 (70.6) Lymph node 35 (56.5) 21 (60) 9 (53) Visceral 26(41.9) 14 (40) 9 (53) Liver 22 (35.5) 11 (31.4) 9 (53) Lung 11 (17.7) 6(17.1) 4 (23.6) Brain 4 (6.5) 3 (8.6) 1 (5.9) Other 4 (6.5) 2 (5.7) 2(11.8) Time from PCA diagnosis to castration-resistance, weeks Median(range) 85 (1-915) 102 (6-915) 79 (1-279) Time from PCA diagnosis tometastasis, weeks Median (range) 9.5 (0-987) 18 (0-987) 2 (0-423) Numberof systemic treatments before plasma collection, n (%) ≤2 37 (59.7) 16(45.7) 12 (70.6) ≥3 25 (40.3) 19 (54.3) 5 (29.4) Type of prior systemictreatments before plasma collection, n (%) Anti-androgens (bicalutamide,nilutamide, flutamide) 21 (33.9) 17 (48.6) 2 (11.8) LHRH agonists(leuprolide, goserelin) 29 (46.8) 23 (65.7) 5 (29.4) LHRH antagonists(degarelix) 20 (32.2) 12 (34.3) 6 (35.3) Sipuleucel T 12 (19.4) 12(34.3) 0 (0) Docetaxel 16 (25.8) 12 (34.3) 3 (17.6) Abiraterone 16(25.8) 14 (40) 1 (5.9) Enzalutamide 4 (6.5) 4 (11.4) 0 (0) Cabazitaxel 4(6.5) 4 (11.4) 0 (0) Radium-223 3 (4.8) 3 (8.6) 0 (0) 177-Lutetium PSMAtherapy 6 (9.7) 6 (17.1) 0 (0) Platinum-based therapy 10 (16.1) 2 (5.7)8 (47.1) Other (ketoconazole, cabozantinib) 1 (1-6) 1 (2.9) 0 (0)Treatments at time of plasma collection, n (%) Anti-androgens(bicalutamide) 4 (6.5) 0 (0) 1 (5.9) LHRH agonists (leuprolide) 5 (8.1)0 (0) 1 (5.9) LHRH antagonists (degarelix) 4 (6.5) 0 (0) 0 (0)Sipuleucel T 0 (0) 0 (0) 0 (0) Docetaxel 7 (11.3) 6 (17.1) 0 (0)Abiraterone 12 (19.4) 9 (25.7) 3 (17.6) Enzalutamide 6 (9.7) 5 (14.3) 0(0) Cabazitaxel 4 (6.5) 4 (11.4) 0 (0) 177-Lutetium PSMA therapy 3 (4.8)3 (8.6) 0 (0) Platinum-based therapy 4 (6.5) 1 (2.9) 3 (17.6)Mitoxantrone 1 (1-6) 1 (2.9) 0 (0) Alisertib 14 (22.6) 6 (17.1) 8 (47.1)PSA before plasma collection, ng/dL 12.1 (0.01-7527) 17.5 (0.5-7527)0.58 (0.01-110.9) Median (range) ALP before plasma collection, U/L 96(35-1009) 92 (42-821) 109 (38-444) Median (range) Hemoglobin beforeplasma 11.8 (7.1-14.7) 11.9 (7.1-14.3) 11 (8.1-13.1) collection, g/dLMedian (range) Albumin before plasma 3.8 (2.2-4.7) 3.9 (2.2-4.7) 3.2(2.8-4.1) collection, g/dL Median (range) LDH before plasma collection,n (%) <192 U/l 36 (64.3) 20 (62.5) 9 (64.3) ≥192# U/l 20 (35.7) 12(37.5) 5 (35.7) Unknown/missing  6  3 3 Serum Neuroendocrine Markers CGAbefore plasma collection, n (%) <95 ng/mL 11 (25) 7 (31.8) 1 (6.7) ≥95#ng/mL 33 (75) 15 (68.2) 14 (93.3) Unknown/missing 18 13 2 NSE beforeplasma collection, n (%) <8.9 mg/L 22 (57.9) 13 (65) 7 (46.7) ≥8.9# mg/L16 (42.1) 7 (35) 8 (53.3) Unknown/missing 24 15 2 * Upper normal value

Abbreviations: ALP, alkaline phosphatase; CGA, chromogranin A;CRPC-Adeno, castration-resistant prostate adenocarcinoma; CRPC-NE,castration resistant prostate adenocarcinoma with neuroendocrinefeatures; HN met PCA, hormone-naïve metastatic prostate cancer; LDH,lactate dehydrogenase; LHRH, luteinizing hormone-releasing hormone; NSE,neuron-specific enolase; PCA, prostate carcinoma; PSA, prostate specificantigen; PSMA, prostate-specific membrane antigen.

TABLE 10 Plasma Samples Clinical Variables CRPC at time of therapy atplasma plasma Age at collection Class at Plasma collection Plasma no =0, plasma collection time Sample Collection yes = 1 collection date(baseline) WCM0 56 0 CRPC-NE Jan. 3, 2013 carboplatin etoposide WCM1 720 HNPC Feb. 6, 2013 degarelix WCM2 73 1 CRPC-Adeno Feb. 21, 2013docetaxel WCM4 59 0 HNPC Mar. 28, 2013 leuprolide, bicalutamide WCM6 761 CRPC-Adeno Mar. 28, 2013 alisertib WCM7 63 1 CRPC-Adeno Apr. 9, 2013etoposide cisplatino WCM9 64 1 CRPC-Adeno Apr. 29, 2013 abirateroneWCM10 86 1 CRPC-NE Apr. 24, 2013 alisertib WCM12 67 1 CRPC-NE Jun. 4,2013 no systemic therapy (radiotherapy cyberknife 5/13) WCM14-TP1 69 1CRPC-Adeno Apr. 26, 2017 mitoxantrone WCM14-TP2 69 1 CRPC-Adeno May 10,2017 mitoxantrone WCM14-TP3 69 1 CRPC-Adeno Jun. 7, 2017 mitoxantroneWCM14-TP4 70 1 CRPC-Adeno Jun. 28, 2017 mitoxantrone WCM15 74 1 CRPC-NEJun. 11, 2013 alisertib WCM63 58 1 CRPC-Adeno Sep. 20, 2013 docetaxel(+MoAb J591) WCM73 87 0 HNPC Aug. 28, 2013 degarelix + leuprolide WCM7879 1 CRPC-Adeno Nov. 12, 2013 alisertib WCM80 65 0 HNPC Sep. 26, 2013leuprolide bicalutamide WCM89 54 1 CRPC-Adeno Sep. 24, 2013 cabazitaxelWCM90 62 1 CRPC-Adeno Oct. 8, 2013 no systemic therapy (bilateralorchiectomy 8/13) WCM91 57 1 CRPC-Adeno Sep. 3, 2014 docetaxel WCM119 661 CRPC-Adeno Nov. 21, 2013 abiraterone WCM121 69 1 CRPC-Adeno Oct. 16,2013 enzautamide WCM124 96 1 CRPC-Adeno Oct. 18, 2013 abiraterone WCM13159 0 HNPC Dec. 3, 2013 degarelix WCM139 77 1 CRPC-Adeno Dec. 4, 2013enzalutamide WCM142 78 1 HNPC Dec. 19, 2013 enzalutamide WCM154 79 1CRPC-NE Jan. 10, 2014 alisertib WCM155 87 1 CRPC-NE Jan. 8, 2014alisertib WCM156 62 1 CRPC-Adeno Dec. 19, 2013 alisertib WCM158 65 1CRPC-Adeno Jan. 28, 2014 Sipuleucel T WCM160 73 0 CRPC-NE Feb. 12, 2014abiraterone WCM161 66 1 CRPC-Adeno Feb. 13, 2014 alisertib WCM162 67 1CRPC-Adeno Feb. 18, 2014 docetaxel WCM163 68 1 CRPC-NE Mar. 5, 2014abiraterone WCM164 81 1 CRPC-Adeno Feb. 18, 2014 Lu 177 DOTA-JR11 WCM16966 0 CRPC-Adeno Apr. 15, 2014 docetaxel gemcitabine WCM170 71 1CRPC-Adeno Mar. 20, 2014 abiraterone WCM172 69 1 CRPC-Adeno Mar. 18,2014 abiraterone WCM176 74 0 HNPC Dec. 15, 2014 leuprolide, bicalutamideWCM183 71 1 CRPC-Adeno Apr. 15, 2014 enzalutamide WCM185 65 1 CRPC-AdenoApr. 30, 2014 cabazitaxel WCM185-TP1 69 1 CRPC-Adeno May 17, 2017mitoxantrone WCM185-TP2 69 1 CRPC-Adeno May 24, 2017 mitoxantroneWCM185-TP3 69 1 CRPC-Adeno May 31, 2017 mitoxantrone WCM185-TP4 69 1CRPC-Adeno Jun. 13, 2017 mitoxantrone WCM192 67 0 CRPC-NE Feb. 5, 2015alisertib WCM195 86 1 CRPC-Adeno Apr. 29, 2014 docetaxel WCM198 66 0CRPC-NE Nov. 26, 2013 alisertib WCM199 67 1 CRPC-Adeno Dec. 23, 2013alisertib WCM201 58 0 HNPC May 12, 2014 NA WCM207 69 0 CRPC-NE May 7,2014 alisertib WCM212 59 1 CRPC-NE May 12, 2014 NA WCM213 71 1CRPC-Adeno May 20, 2014 cabazitaxel WCM216 69 1 CRPC-Adeno Jul. 3, 2014abiraterone + enzalutamide WCM218 64 1 CRPC-Adeno Sep. 16, 2014177Lu-J591 WCM219 67 1 CRPC-Adeno Jul. 8, 2014 abiraterone enzalutamideWCM223 62 1 CRPC-Adeno Nov. 25, 2014 enzalutamide WCM243 78 1 CRPC-NEAug. 20, 2014 abiraterone WCM247 86 0 HNPC Sep. 11, 2014 degarelixWCM252 68 1 CRPC-NE Sep. 3, 2014 alisertib WCM253 74 1 CRPC-NE Oct. 22,2014 carboplatin paclitaxel WCM261 75 1 CRPC-Adeno Oct. 28, 2014abiraterone + prednisone + GDC0068/placebo WCM341 72 1 CRPC-Adeno Nov.17, 2014 alisertib WCM365 80 1 CRPC-Adeno Mar. 18, 2015 NA WCM366 64 0HNPC Mar. 26, 2015 docetaxel WCM369 52 1 CRPC-Adeno Jun. 2, 2015abiraterone (+cabazitaxel) WCM677 93 0 CRPC-NE Dec. 22, 2015bicalutamide leuprolide (Microwave ablation Nov. 13, 2015) WCM1388 81 1CRPC-NE Aug. 1, 2017 Carboplatin/ Paclitaxel number of previous tp linescensor (before Type of start date stop date date of (no = 0, plasmaprevious Sample of therapy of therapy progression yes = 1) collection)tp lines WCM0 Dec. 7, 2012 Jan. 9, 2013 Jan. 9, 2013 1 0 NA WCM1 Feb. 8,2013 Aug. 5, 2014 Aug. 5, 2014 1 1 docetaxel WCM2 Feb. 21, 2013 Jul. 14,2013 Jul. 14, 2013 1 2 degarelix, abiraterone WCM4 Apr. 24, 2013 Aug.20, 2013 Aug. 20, 2013 1 0 NA WCM6 Mar. 28, 2013 Jul. 23, 2013 Jul. 23,2013 1 5 leuprolide, bicalutamide, ketoconazolo, docetaxel, abirateroneWCM7 Apr. 1, 2013 May 28, 2013 Jun. 18, 2013 1 6 degarelix,bicalutamide, docetaxel, abiraterone, enzalutamide, cabazitaxel WCM9Aug. 21, 2013 Feb. 4, 2014 Feb. 4, 2014 1 2 degarelix, bicalutamideWCM10 May 3, 2013 Feb. 2, 2017 Feb. 2, 2017 1 1 leuprolide WCM12 NA NANA NA 0 NA WCM14-TP1 May 10, 2017 Jun. 28, 2017 Jun. 28, 2017 1 9leuprolide, bicalutamide, bicalutamide, abiraterone, radium223,docetaxel, enzlautamide, cabazitaxel, docetaxel WCM14-TP2 May 10, 2017Jun. 28, 2017 Jun. 28, 2017 1 9 leuprolide, bicalutamide, bicalutamide,abiraterone, radium223, docetaxel, enzlautamide, cabazitaxel, docetaxelWCM14-TP3 May 10, 2017 Jun. 28, 2017 Jun. 28, 2017 1 9 leuprolide,bicalutamide, bicalutamide, abiraterone, radium223, docetaxel,enzlautamide, cabazitaxel, docetaxel WCM14-TP4 May 10, 2017 Jun. 28,2017 Jun. 28, 2017 1 9 leuprolide, bicalutamide, bicalutamide,abiraterone, radium223, docetaxel, enzlautamide, cabazitaxel, docetaxelWCM15 Jun. 12, 2013 Jan. 15, 2014 Jan. 15, 2014 1 2 ADT, cisplatinetoposide WCM63 Oct. 1, 2013 Feb. 22, 2014 Mar. 7, 2015 1 3 degarelix,bicalutamide, sipuleucel T WCM73 Aug. 28, 2013 Sep. 11, 2014 Sep. 11,2014 0 0 NA WCM78 Nov. 4, 2013 Mar. 3, 2014 Mar. 3, 2014 1 2 degarelix,abiraterone WCM80 Oct. 29, 2013 Jun. 13, 2017 Jun. 13, 2017 0 1degarelix WCM89 Oct. 2, 2013 May 8, 2014 May 8, 2014 1 4 leuprolide,ketoconazolo, sipuleucel T, MoAb J591 WCM90 NA NA NA NA 4 degarelix,bicalutamide, docetaxel, abiraterone WCM91 Sep. 17, 2014 Dec. 1, 2014Dec. 1, 2014 1 2 degarelix, abiraterone WCM119 Nov. 4, 2013 Feb. 6, 2014Feb. 6, 2014 1 5 leuprolide, bicalutamide, sipuleucel T, docetaxel,enzalutamide WCM121 Aug. 24, 2013 Nov. 4, 2013 Nov. 4, 2013 1 5leuprolide, bicalutamide, nilutamide, sipuleucel T, MoAb J591 WCM124Sep. 22, 2013 Apr. 3, 2014 Apr. 3, 2014 1 4 leuprolide, bicalutamide,sipuleucel T, MoAb J592 WCM131 Nov. 6, 2013 Feb. 18, 2014 Feb. 18, 20141 0 NA WCM139 Nov. 15, 2013 Dec. 24, 2013 Dec. 24, 2013 1 3 goserelin,bicalutamide, abiraterone WCM142 Dec. 29, 2013 Mar. 1, 2014 Mar. 1, 20141 3 leuprolide, bicalutamide, abiraterone WCM154 Jan. 10, 2014 Mar. 31,2014 Mar. 31, 2014 1 2 degarelix, cisplatin etoposide WCM155 Jan. 16,2014 Mar. 17, 2015 Mar. 17, 2015 1 1 leuprolide WCM156 Nov. 22, 2013Jan. 17, 2014 Jan. 17, 2014 1 4 leuprolide, cisplatin etoposide,topotecan, temozolomide etoposide WCM158 Apr. 19, 2014 May 19, 2014 Jul.23, 2014 1 2 leuprolide, bicalutamide WCM160 Nov. 11, 2014 Feb. 24, 2015Feb. 24, 2015 1 3 leuprolide, bicalutamide, carboplatin etoposide WCM161May 21, 2014 Jul. 22, 2014 Jul. 22, 2014 1 5 leuprolide, bicalutamide,MoAb J591, docetaxel, abiraterone WCM162 Feb. 14, 2014 Apr. 29, 2014Jul. 3, 2014 1 1 leuprolide WCM163 Oct. 23, 2013 Feb. 12, 2014 Feb. 12,2014 1 1 degarelix WCM164 Mar. 27, 2014 Apr. 7, 2014 Apr. 7, 2014 1 4leuprolide, docetaxel, enzalutamide, radium223 WCM169 Dec. 11, 2014 Feb.12, 2015 Jul. 3, 2015 1 2 leuprolide, degarelix WCM170 Oct. 2, 2012 Jul.10, 2014 Jul. 10, 2014 1 1 degarelix WCM172 Dec. 26, 2012 Mar. 26, 2015Mar. 26, 2015 1 3 leuprolide, sipuleucel T, docetaxel WCM176 Jun. 16,2014 Dec. 18, 2017 Dec. 18, 2017 0 2 degarelix, bicalutamide WCM183 Apr.15, 2014 Feb. 18, 2015 Feb. 18, 2015 1 8 leuprolide, goserelin, MoAbJ591, docetaxel, cabazitaxel, abiraterone, cabozantinib, radium223WCM185 Oct. 22, 2014 Sep. 16, 2015 Sep. 16, 2015 1 8 leuprolide,bicalutamide, flutamide, MoAb J591, sipuleucel T, abiraterone WCM185-TP1May 24, 2017 Jul. 19, 2017 Jul. 19, 2017 1 9 leuprolide, bicalutamide,flutamide, MoAb J591, sipuleucel T, abiraterone, enzalutamide,docetaxel, 177Lu PSMA WCM185-TP2 May 24, 2017 Jul. 19, 2017 Jul. 19,2017 1 9 leuprolide, bicalutamide, flutamide, MoAb J591, sipuleucel T,abiraterone, enzalutamide, docetaxel, 177Lu PSMA WCM185-TP3 May 24, 2017Jul. 19, 2017 Jul. 19, 2017 1 9 leuprolide, bicalutamide, flutamide,MoAb J591, sipuleucel T, abiraterone, enzalutamide, docetaxel, 177LuPSMA WCM185-TP4 May 24, 2017 Jul. 19, 2017 Jul. 19, 2017 1 9 leuprolide,bicalutamide, flutamide, MoAb J591, sipuleucel T, abiraterone,enzalutamide, docetaxel, 177Lu PSMA WCM192 Feb. 6, 2015 Jun. 9, 2015Jun. 9, 2015 1 3 Degarelix, cisplatin docetaxel, cisplatin etoposideWCM195 Mar. 11, 2014 May 27, 2014 May 27, 2014 1 2 leuprolide,abiraterone WCM198 Nov. 26, 2013 Feb. 28, 2014 Feb. 28, 2014 1 2cisplatin etoposide, topotecan WCM199 Dec. 23, 2013 Feb. 28, 2014 Feb.28, 2014 1 0 NA WCM201 NA NA NA NA 0 NA WCM207 May 8, 2014 Jul. 3, 2014Jul. 3, 2014 1 2 degarelix, carboplatin etoposide WCM212 NA NA NA NA 4leuprolide, abiraterone, docetaxel, carboplatin etoposide WCM213 Jun.17, 2014 Dec. 1, 2014 Dec. 1, 2014 1 4 leuprolide, bicalutamide,docetaxel, abiraterone WCM216 Jun. 5, 2014 Jan. 11, 2018 Jan. 11, 2018 02 leuprolide, sipuleucel T WCM218 Nov. 7, 2014 Feb. 9, 2015 Feb. 9, 20151 1 degarelix WCM219 Jun. 5, 2014 Aug. 13, 2014 May 1, 2017 0 2degarelix, sipuleucel T WCM223 Apr. 11, 2014 Jan. 5, 2017 Jan. 5, 2017 13 degarelix, bicalutamide, sipuleucel T WCM243 Aug. 23, 2014 Feb. 18,2015 Feb. 18, 2015 1 1 degarelix WCM247 Aug. 14, 2014 Feb. 22, 2016 Feb.22, 2016 1 0 NA WCM252 Sep. 3, 2014 Nov. 5, 2014 Nov. 5, 2014 1 3degarelix, cisplatin etoposide, topotecan WCM253 Sep. 25, 2014 Jan. 15,2015 Feb. 3, 2015 1 3 leuprolide, bicalutamide, docetaxel WCM261 Oct.16, 2014 Jan. 16, 2018 Jan. 16, 2018 0 2 leuprolide, docetaxel WCM341Nov. 25, 2014 Feb. 18, 2015 Feb. 18, 2015 1 2 leuprolide, bicalutamideWCM365 NA NA NA NA 9 leuprolide, bicalutamide, abiraterone, sipuleucel,docetaxel, cabazitaxel, enzalutamide, carboplatin, 177Lu-J591 WCM366Mar. 26, 2015 Jul. 9, 2015 Mar. 25, 2016 1 0 NA WCM369 Apr. 14, 2015Nov. 29, 2016 Nov. 29, 2016 1 2 leuprolide, sipuleucel T WCM677 Sep. 24,2013 Apr. 12, 2016 Apr. 12, 2016 1 1 degarelix WCM1388 Aug. 11, 2017Dec. 10, 2017 Dec. 10, 2017 1 0 NA HEMO- Number GLOBIN SERUM Prior ofnext (range ALBUMIN chemo. line Type of 13.3-17.7 (range 3.5- Sample Y/Ntherapy Next Line Therapy g/dL) 4.8 g/dL) WCM0 0 0 NA 13.1 3 WCM1 1 1Docetaxel 12.5 3.1 WCM2 0 3 enzalutamide, carboplatin 11.8 NA taxolo,cabozantinib WCM4 0 4 docetaxel, abiraterone, 13.8 3.6 cabazitaxel,cisplatin eoposide WCM6 1 2 enzalutamide, 11.3 3.7 carboplatin taxoloWCM7 1 1 Carboplatin taxolo 11.13 3.1 WCM9 0 3 docetaxel, enzalutamide,13.3 4.2 cisplatin eoposide WCM10 0 1 enzalutamide NA 4.1 WCM12 0 3docetaxel cisplatin, 11.3 3.9 carboplatin, etoposide CarboplatinWCM14-TP1 1 0 NA 9.8 2.2 WCM14-TP2 1 0 NA 9.2 2.5 WCM14-TP3 1 0 NA 6.92.4 WCM14-TP4 1 0 NA 8.7 2.6 WCM15 1 1 leuprolide 11.4 3.8 WCM63 0 4Enzlautamide, radium223, 13.8 4.1 abiraterone, carboplatin placlitaxelWCM73 0 0 NA 11.2 3.8 WCM78 0 1 Alisertib 13.2 4 WCM80 0 0 NA 13.9 3.7WCM89 0 5 abiraterone, enzalutamide, 13 3.9 radium223, docetaxel,docetaxel carboplatin WCM90 1 0 NA 12 2.2 WCM91 0 1 Docetaxel 10.3 3.5WCM119 1 1 cabazitaxel 13.6 4 WCM121 0 3 docetaxel, abiraterone, 12.74.4 cabazitaxel WCM124 0 0 NA 7.1 3.7 WCM131 0 2 leuprolide,enzalutamide 11.8 4 WCM139 0 4 MoAb J591, docetaxel 13 NA cisplatin,carboplatin paclitaxel, doxorubicin WCM142 0 2 docetaxel, sipuleucel T12.6 4 WCM154 1 1 Alisertib 10.2 NA WCM155 0 1 Alisertib 10.7 3.1 WCM1561 1 Alisertib 14.3 4.3 WCM158 0 1 enzalutamide 13 4.7 WCM160 1 1docetaxel 10 4.1 WCM161 1 0 NA 11.8 3.9 WCM162 0 3 abiraterone,ipatasertib, 12.51 4 cabazitaxel WCM163 0 0 NA 8.1 2.8 WCM164 1 0 NA 123.4 WCM169 0 2 carboplatin etoposide, 12.5 4 doxorubicin WCM170 0 5docetaxel, sipuleucel T, 11.4 3.6 indoximod, radium223, carboplatinWCM172 1 3 cabazitaxel, radium223, 11.6 3.7 carboplatin paclitaxelWCM176 0 1 sipuleucel T 12.5 4.3 WCM183 1 0 NA 10.2 2.8 WCM185 0 4enzalutamide, docetaxel, 9.5 3.4 177Lu PSMA, mitoxantrone WCM185-TP1 1 0NA 8 2.5 WCM185-TP2 1 0 NA 8.1 2.6 WCM185-TP3 1 0 NA 8.7 2.8 WCM185-TP41 0 NA 9.5 3 WCM192 1 0 NA NA NA WCM195 0 1 carboplatin paclitaxel 8.72.8 WCM198 1 0 NA 11.8 3.8 WCM199 0 0 NA 11.9 4.1 WCM201 0 1 leuprolideorteronel 14 3.8 WCM207 1 0 NA NA NA WCM212 1 0 NA 9.6 3 WCM213 1 3enzalutamide, alisertib, 12.5 3.9 pazopanib WCM216 0 0 NA 12.4 4.3WCM218 0 4 docetaxel, enzalutamide, 13.7 4 carboplatin paclitaxel,cabazitaxel WCM219 0 0 NA 11.3 3.9 WCM223 0 2 degarelix, abiraterone14.3 4 WCM243 0 2 docetaxel, radium223 11.2 3.2 WCM247 0 NA NA 12.9 3.7WCM252 1 0 NA 10.5 3.4 WCM253 1 1 alisertib 11 3.2 WCM261 1 0 NA 10.43.8 WCM341 0 1 Alisertib NA NA WCM365 1 0 NA 8.7 2.7 WCM366 NA 1cabazitaxel carboplatin 14.7 4.2 WCM369 0 1 docetaxel 11.7 3.7 WCM677 01 radium223 12 3.2 WCM1388 NA 0 NA NA NA TESTOS- ALP LDH TERONE PSA NSECGA (range (range 98- (range (range 0- (range (range 32-91 192 175-7814.0 ng/ 3.7-8.9 0-95 Sample IU/L) IU/L) ng/dL) mL) ug/L) ng/mL) WCM0 114349 136 0.03 44.2 405 WCM1 1009 270 353 3056 NA 75 WCM2 214 103 NA 2.649.4 222 WCM4 NA 446 199 968.7 NA 48 WCM6 54 NA 6 0.76 4 258 WCM7 586 6605.12 12.12 3.5 1129 WCM9 230 186 NA 1.76 NA 84 WCM10 38 177 NA 3 7.21379 WCM12 77 NA NA 0.01 8.8 319 WCM14-TP1 821 1355 7 111.28 NA NAWCM14-TP2 1326 1793 7 136.42 NA NA WCM14-TP3 1033 754 7 138.14 NA NAWCM14-TP4 782 1201 7 206.09 NA NA WCM15 51 191 176 0.02 12.9 73 WCM63161 189 NA 43.63 7.5 60 WCM73 51 180 409 356.1 NA NA WCM78 161 NA 1037.4 NA NA WCM80 69 139 337 100.14 14.8 138 WCM89 59 178 10 18.19 9 54WCM90 409 165 16 22.25 6.4 2937 WCM91 69 162 NA 27.1 NA NA WCM119 163192 10 11.04 10.2 71 WCM121 74 163 NA 16.8 NA NA WCM124 304 242 NA 1374.6 94 WCM131 125 163 NA 0.46 NA 125 WCM139 NA NA NA 31.14 NA 345 WCM142227 85 NA 14.33 NA NA WCM154 NA 187 10 0.18 4.1 983 WCM155 444 555 NA1.29 61.2 1157 WCM156 71 147 NA 1.83 23.6 NA WCM158 70 147 NA 0.49 NA NAWCM160 109 116 NA 0.65 6.7 420 WCM161 71 228 10 9.63 45.7 192 WCM162 161200 71 65.5 3.9 239 WCM163 236 287 NA 110.9 35.6 17340 WCM164 115 196 1092.65 6.2 89 WCM169 104 215 13 2.56 6.2 129 WCM170 72 132 NA 5 NA NAWCM172 92 106 NA 6.09 NA NA WCM176 35 116 0.11 0.22 NA 49 WCM183 114 178NA 1272.5 12.7 362 WCM185 91 212 10 542.5 3.3 148 WCM185-TP1 147 187 71426 NA NA WCM185-TP2 225 NA 7 2769 NA NA WCM185-TP3 219 NA 7 NA NA NAWCM185-TP4 181 188 7 3124 NA NA WCM192 NA NA NA NA NA NA WCM195 96 364NA 14.72 2.4 333 WCM198 60 173 12 0.03 7.2 115 WCM199 43 180 NA 0.45 NANA WCM201 53 161 NA 2.46 NA NA WCM207 NA 153 10 0.13 6.6 266 WCM212 1351047 10 29.94 370 841 WCM213 42 137 NA 2.2 10.4 78 WCM216 81 170 NA 56.85.6 627 WCM218 83 257 10 6.55 6 107 WCM219 55 135 36 44.91 NA NA WCM22359 149 NA 7527 NA NA WCM243 129 187 NA 0.58 5.8 170 WCM247 115 198 2870.66 3.4 104 WCM252 66 191 NA 0.01 80.2 602 WCM253 318 360 10 44 31.9238 WCM261 86 144 10 1.4 NA NA WCM341 NA 24.27 10 NA NA 1221 WCM365 178155 10 668.6 3.3 242 WCM366 116 153 303 14.6 4.9 119 WCM369 142 211 2178 NA NA WCM677 80 141 10 26 67.1 214 WCM1388 NA NA NA NA NA NA TOTALNadir PSA before PSA/ CEA Date of starting PSA at (range <= death ortherapy 12 weeks PSA 3.0 last alive = 0, (range 0-4.0 if no changeSample mg/mL) follow up dead = 1 ng/mL) decline (%) WCM0 992.8 Jan. 9,2013 1 0.03 0.03 0 WCM1 8.1 Jun. 30, 2016 1 3056 344 −89 WCM2 NA Feb.15, 2014 1 2.64 0.31 −88 WCM4 NA Mar. 6, 2015 1 968.7 277.9 −71 WCM6 2.6Feb. 9, 2016 1 0.76 0.71 −7 WCM7 2.4 Sep. 23, 2013 0 12.12 33.8 179 WCM9NA Sep. 21, 2015 1 1.76 1.54 −13 WCM10 NA Apr. 3, 2017 1 3 4.1 37 WCM122 Jul. 29, 2015 1 NA NA NA WCM14-TP1 NA Aug. 24, 2017 1 111.18 206.09 85WCM14-TP2 NA Aug. 24, 2017 1 111.18 206.09 85 WCM14-TP3 NA Aug. 24, 20171 111.18 206.09 85 WCM14-TP4 NA Aug. 24, 2017 1 111.18 206.09 85 WCM1574.2 Oct. 6, 2015 1 0.02 0.02 0 WCM63 NA Jan. 11, 2018 1 265.9 2.48 −99WCM73 NA Sep. 11, 2014 0 356.1 3.7 −99 WCM78 NA Mar. 3, 2014 1 37.4182.9 389 WCM80 NA Jan. 11, 2018 0 100.14 0.35 −100 WCM89 NA Aug. 13,2017 1 22.25 7.85 −65 WCM90 NA Oct. 9, 2013 1 NA NA NA WCM91 NA Dec. 1,2014 1 27.1 74.6 175 WCM119 NA May 12, 2014 1 11.04 11.19 1 WCM121 NAJun. 7, 2014 1 11.02 39.36 257 WCM124 NA Jun. 19, 2015 1 137 202 47WCM131 NA Jan. 23, 2015 1 0.46 0.19 −59 WCM139 NA Oct. 17, 2014 1 10.231.14 205 WCM142 NA Nov. 27, 2014 1 14.33 61.44 329 WCM154 NA Jun. 19,2014 1 0.18 0.16 −11 WCM155 1287 Apr. 3, 2015 1 1.29 0.88 −32 WCM156 NAOct. 12, 2014 1 1.83 0.13 −93 WCM158 NA Jan. 3, 2018 0 0.74 1.01 36WCM160 NA Jun. 29, 2016 0 18.28 31.18 71 WCM161 NA Aug. 16, 2014 1 26.8480.39 200 WCM162 NA Dec. 12, 2014 1 65.5 7.73 −88 WCM163 NA Mar. 24,2014 1 110.9 210.6 90 WCM164 NA Aug. 7, 2014 1 92.65 213.3 130 WCM169 NAOct. 7, 2015 1 12.29 9.94 −19 WCM170 NA May 4, 2017 0 6.8 0.62 −91WCM172 NA May 24, 2016 1 59.38 3.22 −95 WCM176 NA Dec. 18, 2017 0 0.220.21 −5 WCM183 NA Mar. 7, 2015 1 1272.5 3243 155 WCM185 NA Dec. 14, 20171 542.5 562 4 WCM185-TP1 NA Dec. 14, 2017 1 1426 3124 119 WCM185-TP2 NADec. 14, 2017 1 2769 3124 13 WCM185-TP3 NA Dec. 14, 2017 1 2769 3124 13WCM185-TP4 NA Dec. 14, 2017 1 2769 3124 13 WCM192 NA Jul. 25, 2015 1 NANA NA WCM195 NA Jul. 24, 2014 1 14.72 45.12 207 WCM198 21.8 Feb. 28,2014 0 0.03 0.03 0 WCM199 NA May 1, 2014 1 0.45 0.75 67 WCM201 NA Jan.11, 2018 0 NA NA NA WCM207 NA Aug. 31, 2014 1 0.13 0.83 538 WCM212 NAMay 14, 2014 0 NA NA NA WCM213 NA Apr. 19, 2016 1 2.67 0.6 −78 WCM216 NAJan. 11, 2018 0 56.8 0.06 −100 WCM218 NA Jul. 30, 2016 1 44.93 32.33 −28WCM219 NA May 1, 2017 0 44.91 6.18 −86 WCM223 NA Jan. 25, 2018 0 7527 58−99 WCM243 2.9 Jan. 11, 2016 1 0.58 0.33 −43 WCM247 NA Feb. 22, 2016 10.66 0.01 −98 WCM252 26 Dec. 18, 2014 1 0.01 0.01 0 WCM253 NA Mar. 18,2015 1 36 3.68 −90 WCM261 NA Jan. 18, 2018 0 1.4 0.12 −91 WCM341 NA Feb.18, 2015 0 24.27 35.69 47 WCM365 NA Apr. 24, 2015 1 NA NA NA WCM366 NAAug. 2, 2016 1 14.6 1.32 −91 WCM369 NA Jan. 29, 2017 1 78 1.07 −99WCM677 4.1 Apr. 12, 2016 1 26 0.22 −99 WCM1388 NA Feb. 18, 2018 0 NA NANA

TABLE 11 Plasma and tumor tissue samples genomic data Tumor Missensecontent SNVs SNVs Label in main Sample Class Date Type (TC) Ploidy CNAFload load Site figures WCM0 CRPC- Jan. 3, 2013 Plasma 0.51 1.89 0.406233174 47 NA WCM0_Plasma NE WCM10 CRPC- Apr. 24, 2013 Plasma 0.18 20.002196 23 11 NA NA NE WCM119 CRPC- Nov. 21, 2013 Plasma 0.67 1.840.522444 93 24 NA NA Adeno WCM1 HNPC Feb. 6, 2013 Plasma 0.34 1.970.34136  77 34 NA NA WCM121 CRPC- Oct. 16, 2013 Plasma NA 1.98 NA 15 6NA NA Adeno WCM12 CRPC- Jun. 4, 2013 Plasma 0.1  1.99 0.084694 8 2 NA NANE WCM124 CRPC- Oct. 18, 2013 Plasma NA 1.96 NA 9 1 NA NA Adeno WCM131HNPC Dec. 3, 2013 Plasma NA NA NA 553 152 NA NA WCM1388 CRPC- Aug. 1,2017 Plasma 0.94 1.73 0.452772 NA NA NA NA NE WCM139 CRPC- Dec. 4, 2013Plasma 0.07 1.98 0.212997 20 11 NA NA Adeno WCM142 HNPC Dec. 19, 2013Plasma 0.08 1.99 0.457222 34 13 NA NA WCM14-TP1 CRPC- Apr. 26, 2017Plasma 0.63 3.3 0.914505 99 39 NA WCM14_Plasma1 Adeno WCM14-TP2 CRPC-May 10, 2017 Plasma 0.58 3.1 0.883492 114 42 NA WCM14_Plasma2 AdenoWCM14-TP3 CRPC- Jun. 7, 2017 Plasma 0.3  2.63 0.900793 71 27 NAWCM14_Plasma3 Adeno WCM14-TP4 CRPC- Jun. 28, 2017 Plasma 0.62 3.10.862413 87 32 NA WCM14_Plasma4 Adeno WCM15 CRPC- Jun. 11, 2013 Plasma0.13 2.1 0.777127 38 17 NA NA NE WCM154 CRPC- Jan. 10, 2014 Plasma 0.4 2.6 0.742805 91 36 NA NA NE WCM155 CRPC- Jan. 8, 2014 Plasma 0.75 2.810.815751 106 34 NA NA NE WCM156 CRPC- Dec. 19, 2013 Plasma 0.1  2.020.36514  48 20 NA NA Adeno WCM158 CRPC- Jan. 28, 2014 Plasma 0.22 1.940.118501 22 12 NA NA Adeno WCM160 CRPC- Feb. 12, 2014 Plasma 0.16 20.518303 47 14 NA NA NE WCM161 CRPC- Feb. 13, 2014 Plasma 0.51 2.020.43724  50 14 NA WCM161_Plasma Adeno WCM162 CRPC- Feb. 18, 2014 Plasma0.57 2.27 0.355735 113 30 NA NA Adeno WCM163 CRPC- Mar. 5, 2014 Plasma0.82 2.8 0.844383 90 38 NA NA NE WCM164 CRPC- Feb. 18, 2014 Plasma 0.072.03 0.499529 37 14 NA NA Adeno WCM169 CRPC- Apr. 15, 2014 Plasma 0.06 20.24227  22 8 NA NA Adeno WCM170 CRPC- Mar. 20, 2014 Plasma 0.07 2.040.581636 20 4 NA NA Adeno WCM172 CRPC- Mar. 18, 2014 Plasma NA 1.98 NA21 9 NA NA Adeno WCM176 HNPC Dec. 15, 2014 Plasma NA 1.95 NA 60 29 NA NAWCM183 CRPC- Apr. 15, 2014 Plasma 0.62 2.9 0.857458 419 141 NA NA AdenoWCM185 CRPC- Apr. 30, 2014 Plasma NA 2.04 NA 30 6 NA WCM185_Plasma AdenoWCM185-TP1 CRPC- May 17, 2017 Plasma 0.17 2.17 0.219132 75 17 NAWCM185_Plasma1 Adeno WCM185-TP2 CRPC- May 24, 2017 Plasma 0.76 2.110.212067 90 28 NA WCM185_Plasma2 Adeno WCM185-TP3 CRPC- May 31, 2017Plasma 0.74 2.08 0.166852 88 26 NA WCM185_Plasma3 Adeno WCM185-TP4 CRPC-Jun. 13, 2017 Plasma NA 2.11 NA 46 14 NA WCM185_Plasma4 Adeno WCM192CRPC- Feb. 5, 2015 Plasma NA 2.02 NA 36 12 NA NA NE WCM195 CRPC- Apr.29, 2014 Plasma 0.08 1.99 0.222119 13 5 NA NA Adeno WCM198 CRPC- Nov.26, 2013 Plasma 0.52 2.19 0.377376 150 49 NA NA NE WCM199 CRPC- Dec. 23,2013 Plasma NA 1.97 NA 19 5 NA NA Adeno WCM201 HNPC May 12, 2014 Plasma0.18 1.99 0.073614 12 3 NA NA WCM207 CRPC- May 7, 2014 Plasma 0.7  2.90.695142 86 29 NA NA NE WCM212 CRPC- May 12, 2014 Plasma 0.58 2.70.761776 93 20 NA NA NE WCM213 CRPC- May 20, 2014 Plasma 0.16 1.980.220748 32 11 NA NA Adeno WCM216 CRPC- Jul. 3, 2014 Plasma 0.48 1.973.10E−05 11 2 NA NA Adeno WCM218 CRPC- Sep. 16, 2014 Plasma 0.13 1.990.07904  12 3 NA NA Adeno WCM219 CRPC- Jul. 8, 2014 Plasma 0.05 1.980.313314 21 9 NA NA Adeno WCM2 CRPC- Feb. 21, 2013 Plasma 0.12 2.010.439123 41 12 NA NA Adeno WCM223 CRPC- Nov. 25, 2014 Plasma 0.12 20.072258 14 1 NA NA Adeno WCM243 CRPC- Aug. 20, 2014 Plasma 0.2  2.060.610595 33 13 NA NA NE WCM247 HNPC Sep. 11, 2014 Plasma 0.05 2.040.672381 32 8 NA NA WCM252 CRPC- Sep. 3, 2014 Plasma 0.72 1.98 0.215364397 55 NA NA NE WCM253 CRPC- Oct. 22, 2014 Plasma 0.08 2.03 0.090601 439 NA NA NE WCM261 CRPC- Oct. 28, 2014 Plasma NA 1.98 NA 7 0 NA NA AdenoWCM341 CRPC- Nov. 17, 2014 Plasma 0.29 2.6 0.923577 77 25 NA NA AdenoWCM365 CRPC- Mar. 18, 2015 Plasma 0.58 2.68 0.774055 73 22 NA NA AdenoWCM366 HNPC Mar. 26, 2015 Plasma 0.04 1.96 0.36879  16 8 NA NA WCM369CRPC- Jun. 2, 2015 Plasma 0.07 1.96 0.031945 10 5 NA NA Adeno WCM4 HNPCMar. 28, 2013 Plasma NA 2.04 NA 50 18 NA NA WCM6 CRPC- Mar. 28, 2013Plasma NA 2.04 NA 28 7 NA NA Adeno WCM63 CRPC- Sep. 20, 2013 Plasma 0.152.01 0.363378 24 8 NA NA Adeno WCM677 CRPC- Dec. 22, 2015 Plasma 0.531.95 0.32031  91 23 NA NA NE WCM7 CRPC- Apr. 9, 2013 Plasma 0.22 20.377302 36 12 NA NA Adeno WCM73 HNPC Aug. 28, 2013 Plasma 0.03 2.010.587287 53 14 NA NA WCM78 CRPC- Nov. 12, 2013 Plasma 0.18 2.02 0.14256356 23 NA NA Adeno WCM80 HNPC Sep. 26, 2013 Plasma 0.53 1.95 0.099424 8631 NA NA WCM89 CRPC- Sep. 24, 2013 Plasma NA 1.97 NA 19 8 NA NA AdenoWCM90 CRPC- Oct. 8, 2013 Plasma 0.32 2.01 0.26617  42 16 NA NA AdenoWCM91 CRPC- Sep. 3, 2014 Plasma NA 2.04 NA 34 8 NA NA Adeno WCM9 CRPC-Apr. 29, 2013 Plasma 0.25 1.99 0.006078 22 7 NA NA Adeno WCM0_LM1 CRPC-Jan. 9, 2013 Tissue 0.95 1.72 0.497432 161 77 Liver WCM0_Liverl NEWCM0_LM2 CRPC- Jan. 9, 2013 Tissue 0.96 1.63 0.518523 177 90 LiverWCM0_Liver2 NE WCM0_PM1 CRPC- Jan. 9, 2013 Tissue 0.96 1.63 0.431888 11747 PelvicMass WCM0_PM1 NE WCM0_PM2 CRPC- Jan. 9, 2013 Tissue 0.98 2.070.717882 167 69 PelvicMass WCM0_PM2 NE WCM0_T24 CRPC- Jan. 9, 2013Tissue 0.92 1.66 0.424753 144 62 Lymphnode WCM0_LN2 NE WCM0_T5 CRPC-Jan. 9, 2013 Tissue 0.98 1.7 0.443587 169 78 Lymphnode WCM0_LN1 NEWCM10_Z1-1 CRPC- Apr. 24, 2013 Tissue 0.64 1.98 0.034373 1345 644Lymphnode NA NE WCM119_Z6_1 CRPC- Oct. 15, 2013 Tissue 0.7  3.2 0.875076188 104 Lymphnode NA Adeno WCM121_Z1_1 CRPC- Oct. 18, 2013 Tissue 0.422.7 0.890388 347 178 Lymphnode NA Adeno WCM124_X1_3 CRPC- Oct. 21, 2013Tissue 0.44 3 0.923381 247 154 Bone NA Adeno WCM12_Z10_1 HNPC Jan. 25,2012 Tissue 0.8  2.06 0.251133 490 289 Prostate NA WCM131_Z1_1 CRPC-Nov. 21, 2014 Tissue NA NA NA 1212 614 Bone NA Adeno WCM131_Z2_1 HNPCOct. 29, 2013 Tissue NA NA NA 870 466 Bone NA WCM1388_Z3_1 CRPC- Jul.28, 2017 Tissue 0.93 1.81 0.467737 236 140 Liver NA NE WCM139_Z3_1 CRPC-Dec. 4, 2013 Tissue 0.81 2.34 0.35712  179 113 Bone NA Adeno WCM14_x1_1CRPC- Nov. 26, 2012 Tissue 0.41 2.83 0.875067 52 29 Prostate WCM14_TURPAdeno WCM14_Z11_1 CRPC- Jul. 19, 2017 Tissue 0.7  3 0.870726 624 372Liver WCM14_Liver Adeno WCM154_Z1_1 CRPC- Jan. 7, 2014 Tissue 0.85 3.40.805325 178 103 Bone NA NE WCM155_Z1_1 CRPC- Jan. 8, 2014 Tissue 0.973.15 0.813507 159 88 Liver NA NE WCM155_Z2_1 CRPC- Jan. 31, 2015 Tissue0.71 2.96 0.80734  312 178 GallBladder NA NE WCM156_Z5_1 CRPC- Nov. 20,2013 Tissue 0.52 2.06 0.254913 202 131 Prostate NA Adeno WCM158_X1_1CRPC- Jan. 30, 2014 Tissue 0.3  2.5 0.899495 182 115 Bone NA AdenoWCM15_Z1_1 CRPC- Jun. 11, 2013 Tissue 0.94 1.9 0.51896  112 54 LymphnodeNA NE WCM160_X1_1 CRPC- Feb. 20, 2014 Tissue NA 2 NA 69 43 Bone NA NEWCM160_Z7_1 CRPC- Nov. 4, 2014 Tissue 0.37 2 0.398985 145 85 Bone NAAdeno WCM161_Z1_1 CRPC- Feb. 13, 2014 Tissue 0.74 3.17 0.876004 150 102Bone WCM161_Bone Adeno WCM161_Z15_1 CRPC- May 15, 2014 Tissue 0.96 2.840.768569 152 86 Liver WCM161_Liver NE WCM161_Z6_1 CRPC- Feb. 13, 2014Tissue 0.4  3 0.962918 142 88 Lymphnode WCM161_Lymphnode AdenoWCM162_Z1_1 CRPC- Feb. 14, 2014 Tissue 0.82 2.5 0.439627 218 129 Lung NAAdeno WCM162_Z9_1 CRPC- Jul. 1, 2014 Tissue NA 1.99 NA 146 91 Bone NAAdeno WCM163_Z7_1 CRPC- Feb. 14, 2014 Tissue 0.92 3.05 0.790792 160 99Liver NA NE WCM164_X1_1 CRPC- Feb. 19, 2014 Tissue 0.5  2.9 0.851095 13882 Bone NA Adeno WCM169_X1_1 CRPC- Jun. 30, 2015 Tissue 0.1  2.060.51887  250 164 Bone NA Adeno WCM170_Z1_1 CRPC- Mar. 12, 2014 Tissue0.37 2.07 0.375831 145 92 Bone NA Adeno WCM170_Z16_1 CRPC- Mar. 17, 2017Tissue 0.78 2.09 0.384168 214 121 SpinalCord NA Adeno WCM172_X1_1 CRPC-Mar. 19, 2014 Tissue 0.39 2.7 0.810411 161 101 Bone NA Adeno WCM172_X2_1CRPC- Mar. 5, 2015 Tissue 0.8  3 0.8253  171 96 Bone NA AdenoWCM176_Z1_1 HNPC Mar. 26, 2014 Tissue 0.83 1.93 0.101837 127 71 Lung NAWCM183_Z4_1 CRPC- Apr. 2, 2014 Tissue 0.96 3.7 0.855027 377 229 Liver NAAdeno WCM185_X1_1 CRPC- Jul. 1, 2015 Tissue 0.14 2.04 0.574249 262 177Prostate WCM185_TURP Adeno WCM185_Z1_1 CRPC- Apr. 8, 2014 Tissue 0.812.01 0.137001 117 64 Spine WCM185_Spine Adeno WCM192_X1_1 CRPC- Jan. 26,2015 Tissue 0.83 1.96 0.274942 346 187 Lymphnode NA NE WCM192_Z1_1 CRPC-Apr. 4, 2014 Tissue 0.38 2.5 0.748843 150 76 Prostate NA NE WCM195_Z8_1CRPC- Apr. 10, 2014 Tissue 0.95 3.2 0.908459 160 90 Bladder NA AdenoWCM198_Z1_1 CRPC- Nov. 22, 2013 Tissue 0.98 2.36 0.374634 156 97Lymphnode NA NE WCM199_Z3_1 CRPC- Dec. 5, 2013 Tissue 0.83 2.55 0.502945125 68 Liver NA Adeno WCM1_T HNPC Feb. 15, 2013 Tissue NA 2.01 NA 58 15Bone NA WCM201_Z1_1 CRPC- Oct. 7, 2013 Tissue 0.64 3.1 0.942948 165 97Lymphnode NA Adeno WCM207_X1_1 CRPC- May 7, 2014 Tissue 0.99 3.20.676731 173 110 Liver NA NE WCM212_Z2_1 CRPC- May 12, 2014 Tissue 0.913.06 0.746506 152 84 Softtissue NA NE WCM213_X1_1 CRPC- Mar. 11, 2015Tissue NA 2.6 NA 293 186 Liver NA Adeno WCM213_Z13_1 CRPC- Jun. 4, 2014Tissue NA 2.06 NA 264 163 Liver NA Adeno WCM216_Z1_1 CRPC- Jun. 16, 2014Tissue NA 2.01 NA 143 88 Bone NA Adeno WCM218_Z11_1 CRPC- Apr. 8, 2015Tissue 0.45 2.05 0.298643 216 129 Bone NA Adeno WCM218_Z3_1 CRPC- Jul.23, 2014 Tissue 0.55 2.05 0.282554 210 131 Bone NA Adeno WCM223_Z2_1CRPC- Jun. 9, 2014 Tissue 0.89 1.91 0.073906 243 145 Prostate NA AdenoWCM223_Z4_1 CRPC- Dec. 22, 2016 Tissue 0.94 1.99 0.079075 251 141 BrainNA Adeno WCM243_X1_1 CRPC- Aug. 14, 2014 Tissue 0.63 2.75 0.696385 197110 Bone NA NE WCM247_Z9_1 CRPC- Aug. 25, 2014 Tissue 0.45 1.83 0.641502136 84 Bone NA Adeno WCM252_Z3_1 CRPC- Sep. 3, 2014 Tissue 0.73 2.010.214638 174 84 Liver NA NE WCM253_Z1_1 CRPC- Sep. 12, 2014 Tissue 0.592.9 0.766665 374 235 Liver NA NE WCM261_Z4_1 CRPC- Oct. 14, 2014 Tissue0.47 2.7 0.770169 190 113 Bone NA Adeno WCM2_Z3_1 CRPC- Feb. 19, 2013Tissue 0.43 2.23 0.641158 204 120 Lymphnode NA Adeno WCM341_X1_1_p9CRPC- N/A Tissue 0.49 1.7 0.737809 136 84 Lymphnode NA Adeno WCM341_Z2_1CRPC- N/A Tissue 0.74 1.8 0.473458 175 104 Lymphnode NA AdenoWCM365_Z2_1 CRPC- Mar. 18, 2015 Tissue 0.77 2.99 0.74207  231 138 SkinNA Adeno WCM366_X1_1 CRPC- Mar. 11, 2015 Tissue 0.68 1.9 0.144074 163 85Lymphnode NA Adeno WCM369_Z2_1 CRPC- Apr. 2, 2015 Tissue 0.23 1.980.226305 133 81 Bone NA Adeno WCM4_X1_1 CRPC- Apr. 30, 2014 Tissue 0.242.35 0.764132 210 124 Bone NA Adeno WCM63_X1_1 CRPC- Mar. 6, 2015 TissueNA 1.96 NA 100 62 Bone NA Adeno WCM63_Z1_1 CRPC- Oct. 19, 2016 Tissue0.9  2.87 0.643923 207 125 Bone NA Adeno WCM63_Z19_1 CRPC- Feb. 27, 2017Tissue 0.01 2 0.19152  128 65 Liver NA Adeno WCM63_Z19_2 CRPC- Feb. 27,2017 Tissue 0.65 3.04 0.838218 242 137 Liver NA Adeno WCM63_Z2_1 CRPC-Aug. 26, 2013 Tissue 0.94 1.88 0.545437 171 111 Prostate NA AdenoWCM677_Z12_1 CRPC- Apr. 13, 2016 Tissue 0.99 1.94 0.318251 178 89Lymphnode NA NE WCM677_Z16_1 CRPC- Apr. 13, 2016 Tissue 0.97 1.940.323656 195 100 Lung NA NE WCM677_Z3_1 CRPC- Nov. 13, 2015 Tissue 0.971.96 0.323568 214 117 Bone NA NE WCM677_Z6_1 CRPC- Apr. 13, 2016 Tissue0.99 2.01 0.338037 187 107 Peritoneum NA NE WCM677_Z7_1 CRPC- Apr. 13,2016 Tissue 0.99 2.03 0.362   202 111 Bone NA NE WCM677_Z9_1 CRPC- Apr.13, 2016 Tissue 0.99 2.01 0.352733 204 112 Liver NA NE WCM6_Z5_1 CRPC-Aug. 22, 2013 Tissue 0.9  3.6 0.825182 271 158 Lymphnode NA AdenoWCM73_X1_1 HNPC Aug. 28, 2013 Tissue 0.35 1.99 0.077676 147 82 ProstateNA WCM78_Z1_1 CRPC- Sep. 10, 2013 Tissue 0.65 2.18 0.243562 192 117Lymphnode NA Adeno WCM7_Tissue CRPC- Mar. 28, 2013 Tissue 0.78 1.960.378935 223 91 Liver NA Adeno WCM80_Z1_1 HNPC Sep. 17, 2013 Tissue 0.691.98 0.096276 168 109 Bone NA WCM89_X1_1 CRPC- May 22, 2015 Tissue 0.671.83 0.444335 164 92 Lymphnode NA Adeno WCM89_Z1_1 CRPC- Apr. 16, 2013Tissue 0.39 2.04 0.245254 186 114 Lymphnode NA Adeno WCM89_Z12_1 CRPC-Mar. 22, 2010 Tissue 0.41 2.09 0.007271 299 174 Prostate NA AdenoWCM89_Z17_1 CRPC- Mar. 22, 2010 Tissue 0.4  2.1 0.163111 441 274Prostate NA Adeno WCM89_ZLN1_1 CRPC- Mar. 22, 2010 Tissue 0.38 2.110.100778 400 247 Lymphnode NA Adeno WCM90_Z1_1 CRPC- Oct. 8, 2013 Tissue0.7  3.1 0.898564 173 100 Liver NA Adeno WCM90_Z19_1 CRPC- Oct. 8, 2013Tissue 0.3  2.01 0.380803 130 87 Lymphnode NA Adeno WCM90_Z21_1 CRPC-Oct. 8, 2013 Tissue 0.83 2 0.507591 178 110 Liver NA Adeno WCM90_Z25_1CRPC- Oct. 8, 2013 Tissue NA 1.97 NA 141 96 Lymphnode NA AdenoWCM90_Z29_1 CRPC- Oct. 8, 2013 Tissue 0.25 2.43 0.800655 154 95 Bone NAAdeno WCM91_Z1_1 CRPC- Aug. 18, 2014 Tissue 0.75 3 0.840813 138 89Prostate NA Adeno WCM9_X1_1 CRPC- Jan. 30, 2014 Tissue 0.23 2.4 0.868995222 89 Bone NA Adeno WCM9_Z3-1 CRPC- Apr. 17, 2013 Tissue 0.5  2.150.249972 157 73 Prostate NA Adeno

Tumor/normal whole exome sequencing (WES) was performed on cell free DNA(cfDNA) extracted from plasma and germline DNA from peripheral bloodmononuclear cells (PBMCs) with a median depth of coverage of 357× forplasma samples and 105× for germline samples. Median cfDNA tumor content(TC) was 22% [3%-94%], and TC did not associate with histology subtype(i.e., adenocarcinoma or CRPC-NE) (FIG. 2 ), number or type ofmetastatic sites, prostate specific antigen (PSA) levels, serumneuroendocrine markers, or number of prior systemic therapies (FIGS.3A-3C). Prior exposure to cytotoxic chemotherapy was associated withhigher cfDNA TC (FIG. 3D), and no statistical difference in TC wasobserved with respect to presence or absence of sites of metastasis(bone, lymph node or visceral) in chemotherapy-treated patients. Inpatients with CRPC-Adeno, a cfDNA TC >50% was associated with inferiorprognosis (p=0.01, FIG. 4A), but this was not observed in the CRPC-NEsubclass. Tumor mutation load and copy number burden in ctDNA did notdiffer significantly between tumor histologies, but both were higher inpatients that received prior chemotherapy compared to those that did not(FIG. 3D). Recurrent genomic alterations observed in plasma and intissue samples of study cohort samples detected by WES are shown inFIGS. 1B-1C and FIG. 5 .

Overall, copy number alterations and point mutations involving commonlyaltered prostate cancer associated genes (Table 12) detected inmetastatic biopsy tissue samples were evident in patient-matched ctDNA(median concordance 71%, range from 0.29 to 1). This degree ofconcordance was similar to other targeted DNA and WES prostate cancerctDNA studies (Wyatt et al. (2017) J Natl Cancer Inst 109: doi:10.1093/jnci/djx118; Adalsteinsson et al. (2017) Nat Commun 8:1324). Asexpected based on prior studies (Abida et al. (2019) Proc Natl Acad SciUSA 116:11428-11436; Beltran et al. (2016) Nat Med 22:298-305),alterations involving RB1, TP53, and CYLD were more common in the ctDNAand biopsy tissues of CRPC-NE patients, AR alterations more common inCRPC-Adeno. There were no significant differences in the frequency ofDNA repair gene aberrations involving BRCA1, BRCA2, ATM between thesubtypes (FIGS. 1B and 5 , Table 8). SPOP mutations were notably absentin CRPC-NE. The most common genomic alterations in ctDNA of mPCApatients included TP53 (43%), RB1 (38%), FANCA (25%), in CRPC-Adeno wereAR (42%), TP53 (37%), and in CRPC-NE were RB1 (69%), TP53 (63%). Asobserved in prior studies (Romanel et al. (2015) Sci Transl Med7:312re310; Azad et al. (2015) Clin Cancer Res 21:2315-2324), thepresence of AR aberrations in the ctDNA of CRPC-Adeno patients wasassociated with inferior overall survival (p=0.009), which wasmaintained after adjustment for TC (multivariate p=0.028, FIG. 4B). Ofnote, AR focal gains could be either persistent or dynamic whencomparing serial samples in individuals with CRPC-Adeno (FIG. 1D)supporting evolution of somatic AR aberrations. The prognostic value ofother specific gene aberrations in CRPC-Adeno was consistent with arecent study by Annala et al (Annala et al. (2018) Cancer Discov8:444-457). The presence of TP53 and/or RB1 loss of function alterationsin the ctDNA of patients with CRPC-Adeno (but not CRPC-NE) associatedwith worse overall survival (p=0.006), including after accounting for TC(multivariate p=0.006, FIG. 4C). Somatic alterations involving BRCA1,BRCA2, or ATM were also prognostic across the cohort (p=0.008multivariate, FIG. 4D).

TABLE 8 Frequency of somatic aberrations in CRPC-NE vs CRPC-Adeno TotFreq. Tot Freq. in Gene CRPC- CRPC- CRPC- CRPC- CRPC- CRPC- P-valueP-value Symbol NE NE NE Adeno Adeno Adeno (two sided) (one sided) SCNA(gain for AR and allele-specific CN = 0|0, 1|0, 2|0 or N|0 for all othergenes) BRCA1 2 16 0.125 2 26 0.077 0.628339141 0.494773519 BRCA2 6 160.375 8 27 0.296 0.738806798 0.418793442 CDKN2A 4 15 0.267 2 26 0.0770.168343568 0.117140247 APC 3 16 0.188 5 27 0.185 1 0.641746861 CHD1 316 0.188 6 27 0.222 1 0.739730625 RB1 11 16 0.688 8 27 0.296 0.0248353630.014353073 CDKN1B 8 16 0.500 3 27 0.111 0.009547745 0.007281075 TP53 1016 0.625 9 27 0.333 0.111247733 0.061240502 CYLD 7 16 0.438 4 27 0.1480.067919147 0.042185777 PTEN 7 15 0.467 3 25 0.120 0.0237452230.019889009 FANCA 8 16 0.500 8 27 0.296 0.208984468 0.156451431 AR 2 160.125 8 23 0.348 0.1523318 0.1149152 Non-synonymous SNV TP53 3 16 0.18752 35 0.057 0.3445601 0.17228 FOXA1 2 16 0.125 1 35 0.029 0.47354160.2367708 SPOP 0 16 0 3 35 0.086 1 1 RB1 2 16 0.125 0 35 0.000 0.1749220.08746101 BRCA2 0 16 0 0 35 0.000 1 1 Non-synonymous SNVs or SCNA (gainfor AR and allele-specific CN = 0|0, 1|0, 2|0 or N|0 for all othergenes) RB1 11 16 0.688 8 26 0.308 0.025814876 0.018260359 AR 2 16 0.1259 24 0.375 0.1478246 0.08252297 Bold indicates p-values < 0.05

TABLE 12 Concordance in genomic losses across plasma and matched tissuesamples (TC > 0.1) Hugo Fraction of loss signal in Fraction of losssignal in symbol tissue found in plasma plasma found in tissue TP53 0.890.67 RB1 0.76 0.54 FANCA 0.94 0.74 BRCA2 0.71 0.71 CDKN1B 0.62 0.38 CYLD0.69 0.64 PTEN 1 0.43 CHD1 0.55 0.55 APC 0.5 0.5 CDKN2A 0.75 0.38 BRCA10.29 0.33

A subset of alterations detected in ctDNA was not detected in matchedtissue samples (FIG. 5 ); though false negative calls cannot beexcluded, it is likely that intra-patient tumor heterogeneity is aprominent reason for these differences, whereby the sampled metastasisdid not fully capture the genomic status of the patient's cancer burden.In order to quantify and contextualize the degree of CRPC-NE intra- andinter-patient heterogeneity by comparing metastatic tissue and liquidbiopsies, the distributions of genome-wide heterogeneity levels amongall metastatic tissue biopsies of both CRPC-Adeno and CRPC-NE were firstbuilt using their genomic profiles (WES data). While there was generallygenomic concordance across metastatic tissues in either subtype (FIG.6A), the CRPC-NE subtype demonstrated significantly greaterinter-individual similarity both for somatic copy number alterations(SCNA) and for single nucleotide variants (SNVs) (FIG. 6A). Importantly,this finding was irrespective of the anatomic site of the metastaticbiopsy assessed as indicated by similarities stratified by site andacross sites (FIG. 6B). Higher intra-patient genomic similarity was alsoobserved when comparing ctDNA and biopsy samples within individuals withCRPC-NE (FIGS. 6C and 7 ) compared to CRPC-Adeno patients. If a plasmasample represents the genomics of all or most of an individual'smetastases released into the circulation, a higher concordance betweenctDNA and single site biopsy indicates lower intra-patient tumorheterogeneity in CRPC-NE. However, differential contribution or releaserates of individual metastases into the circulation cannot be fullyexcluded. For instance, inspection of the relative contributions intothe plasma of six spatially distinct metastases (with 74% of averagegenomic similarity with one another) of one CRPC-NE patient all obtainedat the same time-point supported a higher contribution of livermetastasis tumor alterations in cfDNA compared with other sites (FIG.6D).

In order to further explore intra-patient heterogeneity across thecohort, allele-specific copy number analysis (Prandi and Demichelis(2019) Curr Protoc Bioinformatics 67:e81) of WES data was leveraged.While the vast majority of alterations were identified as shared betweenctDNA and metastatic biopsies (FIGS. 8A and 9A), this higher resolutionanalysis allowed for the identification of distinct subclonaldifferences (as illustrated by cases examples in FIGS. 8B and 9B; bluegenes demonstrate different allele-specific status between tissue andplasma samples). These differences can represent private events inmetastatic lesions that are therefore differentially represented in thecirculation; diversity can be restricted to a small set of lesions (FIG.8B) or to a wide range of structural differences, resulting inallele-specific diversity (FIG. 9B). Overall these data supportsubclonal heterogeneity in metastatic lesions that can not be detectedby single site biopsy but can also contribute to the development oftherapy resistance.

To explore how genomic alterations can change with time, serial tumorand blood samples from individuals were evaluated (FIGS. 10 and 11 ,Table 13). In patient WCM161, metastatic biopsy time-points duringclinical progression from CRPC-Adeno to CRPC-NE were tracked.Interestingly, the plasma sample obtained at the time of CRPC-Adeno withlymph node and bone metastases present displayed a genomic ctDNA profilemost similar (based on whole exome-wide comparison) to the CRPC-NE livermetastasis observed on imaging and biopsied three months later at thetime of progression on abiraterone (FIG. 10A), supporting the presenceof detectable resistant clones in the circulation prior to thedevelopment of clinical features of CRPC-NE or liver metastases.

TABLE 13 Somatic copy number aberration-based distance among plasma andmatched tissue samples Plasma Tissue Similarity LOSS Similarity GAINType WCM156 WCM156_Z5_1 0.46 0.33 CRPC-Adeno WCM2 WCM2_Z3_1 0.26 0.32CRPC-Adeno WCM15 WCM15_Z1_1 0.68 0.9 CRPC-NE WCM218 WCM218_Z11_1 NA 0.03CRPC-Adeno WCM218 WCM218_Z3_1 NA 0.03 CRPC-Adeno WCM63 WCM63_Z2_1 0.290.25 CRPC-Adeno WCM63 WCM63_Z1_1 0.34 0.25 CRPC-Adeno WCM63 WCM63_Z19_20.39 0.34 CRPC-Adeno WCM160 WCM160_Z7_1 0.56 0.52 CRPC-Adeno WCM185WCM185_X1_1 NA 0.13 CRPC-Adeno WCM185 WCM185_Z1_1 0.38 0.65 CRPC-AdenoWCM78 WCM78_Z1_1 0.3 0.14 CRPC-Adeno WCM243 WCM243_X1_1 0.8 0.84 CRPC-NEWCM158 WCM158_X1_1 0.01 0.01 CRPC-Adeno WCM7 WCM7_Tissue 0.97 0.88CRPC-Adeno WCM9 WCM9_Z3-1 NA 0.12 CRPC-Adeno WCM341 WCM341_X1_1_p2 0.480.68 CRPC-Adeno WCM341 WCM341_Z2_1 0.62 0.97 CRPC-Adeno WCM90 WCM90_Z1_10.73 0.7 CRPC-Adeno WCM90 WCM90_Z19_1 0.61 0.34 CRPC-Adeno WCM90WCM90_Z21_1 0.34 0.85 CRPC-Adeno WCM90 WCM90_Z29_1 0.8 0.46 CRPC-AdenoWCM154 WCM154_Z1_1 0.8 0.82 CRPC-NE WCM0 WCM0_LM1 0.5 0.82 CRPC-NE WCM0WCM0_LM2 0.59 0.97 CRPC-NE WCM0 WCM0_PM1 0.22 0.92 CRPC-NE WCM0 WCM0_PM20.22 0.93 CRPC-NE WCM0 WCM0_T24 0.27 0.94 CRPC-NE WCM0 WCM0_T5 0.2 0.93CRPC-NE WCM161 WCM161_Z1_1 0.26 0.37 CRPC-Adeno WCM161 WCM161_Z15_1 0.610.62 CRPC-NE WCM161 WCM161_Z6_1 0.42 0.42 CRPC-Adeno WCM198 WCM198_Z1_10.89 0.88 CRPC-NE WCM677 WCM677_Z12_1 1 0.83 CRPC-NE WCM677 WCM677_Z16_11 0.85 CRPC-NE WCM677 WCM677_Z3_1 0.99 0.99 CRPC-NE WCM677 WCM677_Z6_10.79 0.95 CRPC-NE WCM677 WCM677_Z7_1 0.68 0.99 CRPC-NE WCM677WCM677_Z9_1 0.68 0.95 CRPC-NE WCM162 WCM162_Z1_1 0.65 0.54 CRPC-AdenoWCM212 WCM212_Z2_1 0.52 0.86 CRPC-NE WCM365 WCM365_Z2_1 0.47 0.6CRPC-Adeno WCM183 WCM183_Z4_1 0.55 0.76 CRPC-Adeno WCM119 WCM119_Z6_10.69 0.85 CRPC-Adeno WCM207 WCM207_X1_1 1 0.97 CRPC-NE WCM14 WCM14_x1_10.27 0.43 CRPC-Adeno WCM14 WCM14_Z11_1 0.74 0.63 CRPC-Adeno WCM252WCM252_Z3_1 1 0.97 CRPC-NE WCM155 WCM155_Z1_1 0.82 0.99 CRPC-NE WCM155WCM155_Z2_1 0.64 0.96 CRPC-NE WCM163 WCM163_Z7_1 0.35 0.34 CRPC-NEWCM1388 WCM1388_Z3_1 0.66 0.93 CRPC-NE

To delve deeper into tumor dynamics, short-interval serial time-pointsof two patients with metastatic CRPC progressing after multiple lines ofsystemic therapy (FIG. 10B) were assessed. Patient WCM185 is a patientwith a rising PSA >3000 ng/ml, bone-only metastases, a clinical pictureindicative of AR-driven progression. Patient WCM14 developed newvisceral metastases despite a non-rising PSA, clinical features commonlyobserved in CRPC-NE. Three weekly serial plasma time-points of patientWCM185 were compared with WES data from his CRPC-Adeno tumor/plasmaspecimens collected over the three years prior. When corrected forploidy and TC, distinct clones were identified in ctDNA including thosewith and without AR mutations and TP53 deletions that changeddynamically with time, indicating multiple clones within the circulationwith competing frequencies. This fast evolution in tumor clones even inthe absence of therapy is consistent with clonal disequilibrium. On theother hand, four serial samples of patient WCM14, as well as his tumortissue samples collected five years earlier when he had minimalmetastatic disease burden, all showed consistent alterations includingMYC gain and RB1, TP53, PTEN, and BRCA2 losses across all time-pointsindicating these were relatively early events. Of note, concurrent lossof RB1 and TP53, frequently associated with small cell carcinomasincluding CRPC-NE, was detectable before he had developed clinicalfeatures of AR independence or CRPC-NE (FIG. 10B).

These data indicate that in some cases, CRPC can be dominated by a clonethat arises early where, in other cases, subclones evolve and contributeto treatment resistance. By using ctDNA to track clones with a selectiveadvantage with those that are less fit, tumor dynamics during prostatecancer progression can be better understood. In the setting of CRPC-NE,intrinsic drug resistance is likely a major factor that contributes tothe development of clonal dominance. However, other biological factors,including a proliferative advantage, the local microenvironment, andepigenetic alterations also likely play a role.

Epigenetic variability contributes to the diversity of phenotypesobserved in cancer and other diseases and has been shown to play a keyrole in differentiation and phenotypic plasticity (Feinberg (2007)Nature 447:433-440). Conserved DNA methylation patterns acrossmetastases has also been observed in patients with lethal prostatecancer (Aryee et al. (2013) Sci Transl Med 5:169ra110), supportingrelative stability of DNA methylation patterns at least in late stagedisease. Significant differences between DNA methylation patterns ofCRPC-NE tissues compared to CRPC-Adeno had previously been identified(Beltran et al. (2016) Nat Med 22:298-305). In order to see if thesechanges are also captured by cfDNA, whole genome bisulfite sequencing ofcfDNA was performed from five patients with CRPC-Adeno and six patientswith CRPC-NE and compared these methylation profiles with those of theirmatched tumor biopsies (Table 5). Inference of cfDNA tumor content byDNA methylation using a methodology previously described (Benelli,Romagnoli, and Demichelis (2018) Bioinformatics 34:1642-1649) revealedno differences between CRPC-Adeno and CRPC-NE and was consistent withcopy number-based tumor content data from WES of the same samples (FIG.12A and FIG. 13B). Comparative analysis between plasma and biopsy tissuemethylome data genome-wide (FIG. 12C and FIG. 13A) demonstrated overallconcordance of differentially methylated regions in CRPC-NE (bothhypo-methylated and hyper-methylated sites as shown in FIG. 13E). Thisincluded methylation of specific neuroendocrine prostate cancerclassifier genes reported in Beltran et al. (Benelli, Romagnoli, andDemichelis (2018) Bioinformatics 34:1642-1649) such as ASXL3 and SPDEF,as well as hypomethylation of overexpressed CRPC-NE genes including theneuroendocrine marker INSM1 and the plasticity gene CDH2 (Table 7, FIG.13C). Differentially methylated regions detectable by cfDNA were able tosegregate patients with CRPC-Adeno or CRPC-NE (FIG. 12B and FIG. 13D).Clustering based on the location of metastases was not observed. Thispotentially indicates that cfDNA methylation patterns in the circulationare distinguishable based on their resistance subclass more so than bythe anatomic sites of metastases within a given patient. To increase thestudy sample size, DNA methylation profiles were queried from apublished independent cohort of 33 metastatic CRPC patients at baselineand after treatment with abiraterone acetate (Gordeviĉius et al. (2018)Clin Cancer Res 24:3317-3324).

TABLE 7 chr start end rockermeth.q_value beta_difference meth.stateDMR_set chr1 833806 834358 0.003871035 30.95833333 Hyper-methylatedPCa|NT DMRs chr1 841565 843221 0.000203452 48.13401361 Hyper-methylatedPCa|NT DMRs chr1 861132 861612 1.20E−09 27.4505102 Hyper-methylatedPCa|NT DMRs chr1 863044 863496 0.00064571  −46.4047619 Hypo-methylatedPCa|NT DMRs chr1 868475 869290 0.000553051 −36.01150794 Hypo-methylatedPCa|NT DMRs chr1 906156 907273 2.05E−05 24.38439716 Hyper-methylatedPCa|NT DMRs chr1 932306 934055 1.33E−12 32.65304233 Hyper-methylatedPCa|NT DMRs chr1 975466 975799 1.69E−08 39.06122449 Hyper-methylatedPCa|NT DMRs chr1 986064 986804 5.92E−05 −36.47833333 Hypo-methylatedPCa|NT DMRs chr1 997828 997902 0.000205174 24.12202381 Hyper-methylatedPCa|NT DMRs chr1 998341 998576 0.007560755 −24.07671958 Hypo-methylatedPCa|NT DMRs chr1 1009258 1009572 0.000783791 −42.96285714Hypo-methylated PCa|NT DMRs chr1 1108955 1109833 1.67E−11 24.57083333Hyper-methylated PCa|NT DMRs chr1 1117473 1118863 3.20E−08 29.47852814Hyper-methylated PCa|NT DMRs chr1 1168821 1169484 8.05E−08 −40.97532468Hypo-methylated PCa|NT DMRs chr1 1173013 1173360 2.78E−08 −27.97893773Hypo-methylated PCa|NT DMRs chr1 1181371 1182659 1.84E−19 32.66869301Hyper-methylated PCa|NT DMRs chr1 1207459 1208406 0.003530139−28.29329004 Hypo-methylated PCa|NT DMRs chr1 1216835 1217837 1.70E−05−39.23003663 Hypo-methylated PCa|NT DMRs chr1 1223108 1227515 2.06E−06−21.73966318 Hypo-methylated PCa|NT DMRs chr1 1240237 1241791 1.34E−0530.36530612 Hyper-methylated PCa|NT DMRs chr1 1244638 12453390.000279338 −23.22832723 Hypo-methylated PCa|NT DMRs chr1 12896861290529 1.75E−12 25.99252874 Hyper-methylated PCa|NT DMRs chr1 13069541307443 0.002843063 26.42261905 Hyper-methylated PCa|NT DMRs chr11376954 1377657 0.005968871 −22.06084656 Hypo-methylated PCa|NT DMRschr1 1395851 1397240 2.04E−05 29.15826331 Hyper-methylated PCa|NT DMRschr1 1408204 1408364 6.42E−05 −43.0952381 Hypo-methylated PCa|NT DMRschr1 1444231 1444417 0.005968871 34.17142857 Hyper-methylated PCa|NTDMRs chr1 1449165 1449332 5.94E−06 −22.76493506 Hypo-methylated PCa|NTDMRs chr1 1475013 1475956 1.41E−22 28.46745027 Hyper-methylated PCa|NTDMRs chr1 1510744 1519232 0.001478325 −23.87453416 Hypo-methylatedPCa|NT DMRs chr1 1551815 1552238 0.006190613 −30.71607143Hypo-methylated PCa|NT DMRs chr1 1602789 1602925 0.001969641 −36.1484127Hypo-methylated PCa|NT DMRs chr1 1606890 1609822 2.20E−10 30.65119048Hyper-methylated PCa|NT DMRs chr1 1689453 1691452 5.02E−10 −37.8034632Hypo-methylated PCa|NT DMRs chr1 1695797 1697576 2.42E−05 42.46290727Hyper-methylated PCa|NT DMRs chr1 1823380 1823484 0.000231104 26.3Hyper-methylated PCa|NT DMRs chr1 1825861 1826228 0.005968871−51.40952381 Hypo-methylated PCa|NT DMRs chr1 1830581 18314960.000570576 36.02486772 Hyper-methylated PCa|NT DMRs chr1 19504151950521 7.44E−06 24.18095238 Hyper-methylated PCa|NT DMRs chr1 19785401979100 0.00051204  27.80238095 Hyper-methylated PCa|NT DMRs chr12013800 2014245 0.005968871 −60.71714286 Hypo-methylated PCa|NT DMRschr1 2057319 2058636 0.000411236 28.56613757 Hyper-methylated PCa|NTDMRs chr1 2075932 2082443 0.000226774 45.09238095 Hyper-methylatedPCa|NT DMRs chr1 2121111 2124399 5.90E−08 −23.57375661 Hypo-methylatedPCa|NT DMRs chr1 2136909 2137665 2.48E−08 25.92175824 Hyper-methylatedPCa|NT DMRs chr1 2144913 2144998 8.17E−05 21.11688312 Hyper-methylatedPCa|NT DMRs chr1 2222218 2223007 0.000860601 37.41385281Hyper-methylated PCa|NT DMRs chr1 2230768 2233721 3.18E−10 40.87057387Hyper-methylated PCa|NT DMRs chr1 2253541 2253851 0.00024962820.55952381 Hyper-methylated PCa|NT DMRs chr1 2254128 2255441 8.84E−09−22.32430213 Hypo-methylated PCa|NT DMRs chr1 2273416 22736100.00179283  −25.16071429 Hypo-methylated PCa|NT DMRs chr1 23359632337519 2.40E−06 −23.93361345 Hypo-methylated PCa|NT DMRs chr1 23910102391691 2.67E−05 −39.64217687 Hypo-methylated PCa|NT DMRs chr1 23989522399054 0.00064571  23.12585034 Hyper-methylated PCa|NT DMRs chr12496056 2497941 0.001083007 −22.66 Hypo-methylated PCa|NT DMRs chr12541092 2541937 0.000696555 −29.35324675 Hypo-methylated PCa|NT DMRschr1 2564998 2569756 1.67E−05 −26.14484127 Hypo-methylated PCa|NT DMRschr1 2889964 2890447 0.000481535 20.03703704 Hyper-methylated PCa|NTDMRs chr1 2987330 2988549 1.24E−09 24.68901099 Hyper-methylated PCa|NTDMRs chr1 3230300 3237142 4.87E−07 −33.46066253 Hypo-methylated PCa|NTDMRs chr1 3251914 3252004 0.008482405 −69.11428571 Hypo-methylatedPCa|NT DMRs chr1 3255907 3263385 4.71E−07 −29.36917293 Hypo-methylatedPCa|NT DMRs chr1 3265179 3266823 1.62E−10 −30.5044733 Hypo-methylatedPCa|NT DMRs chr1 3321503 3325095 1.56E−15 −25.76432607 Hypo-methylatedPCa|NT DMRs chr1 3397205 3399514 0.000680799 20.16026786Hyper-methylated PCa|NT DMRs chr1 3412502 3412634 0.000858283 30.4969697Hyper-methylated PCa|NT DMRs chr1 3432220 3436195 0.00011873320.72708995 Hyper-methylated PCa|NT DMRs chr1 3454859 3455550 7.57E−0541.04166667 Hyper-methylated PCa|NT DMRs chr1 3470175 34704400.00064571  −43.92176871 Hypo-methylated PCa|NT DMRs chr1 34964973497778 0.000286886 −20.83766234 Hypo-methylated PCa|NT DMRs chr13498249 3498791 3.66E−05 −27.54333333 Hypo-methylated PCa|NT DMRs chr13503996 3504148 0.001969641 −53 Hypo-methylated PCa|NT DMRs chr1 35937163595670 8.24E−05 35.22134647 Hyper-methylated PCa|NT DMRs chr1 36883533688626 0.003544378 31.35238095 Hyper-methylated PCa|NT DMRs chr13793061 3797937 0.009049402 22.2 Hyper-methylated PCa|NT DMRs chr13807161 3808428 0.000117699 21.90692641 Hyper-methylated PCa|NT DMRschr1 3832884 4005884 1.48E−10 −27.74664723 Hypo-methylated PCa|NT DMRschr1 4008234 4058997 2.33E−18 −35.05553571 Hypo-methylated PCa|NT DMRschr1 4060225 4087186 2.81E−19 −35.11046058 Hypo-methylated PCa|NT DMRschr1 4093526 4117451 1.68E−07 −34.3547619 Hypo-methylated PCa|NT DMRschr1 4587426 4593526 5.84E−05 −43.68315018 Hypo-methylated PCa|NT DMRschr1 4722530 4736275 2.56E−05 −26.49188713 Hypo-methylated PCa|NT DMRschr1 4790174 4794300 0.000768419 −39.51465201 Hypo-methylated PCa|NTDMRs chr1 4829849 4832644 2.81E−09 −29.51684982 Hypo-methylated PCa|NTDMRs chr1 4851218 4995869 3.41E−11 −34.58172757 Hypo-methylated PCa|NTDMRs chr1 5001929 5046353 1.31E−13 −28.73313764 Hypo-methylated PCa|NTDMRs chr1 5335385 5554029 1.49E−45 −30.9928836 Hypo-methylated PCa|NTDMRs chr1 5676228 5676419 6.42E−05 −25.62962963 Hypo-methylated PCa|NTDMRs chr1 5712462 5745743 0.000240645 −23.53783784 Hypo-methylatedPCa|NT DMRs chr1 5795237 5805262 0.001480644 −26.75571429Hypo-methylated PCa|NT DMRs chr1 5814791 5829233 3.20E−14 −24.03341837Hypo-methylated PCa|NT DMRs chr1 5901850 5905277 0.005968871 −28.4015873Hypo-methylated PCa|NT DMRs chr1 6008515 6009858 0.00068166 −44.50595238 Hypo-methylated PCa|NT DMRs chr1 6046227 60468720.007305013 −51.41071429 Hypo-methylated PCa|NT DMRs chr1 60533416054950 0.003949974 37.8989011 Hyper-methylated PCa|NT DMRs chr1 60941176095514 0.000109224 −30.61761905 Hypo-methylated PCa|NT DMRs chr16142719 6142965 0.005968871 25.15619048 Hyper-methylated PCa|NT DMRschr1 6155169 6155484 0.001065506 −30.27472527 Hypo-methylated PCa|NTDMRs chr1 6162700 6166714 7.82E−07 −22.00401003 Hypo-methylated PCa|NTDMRs chr1 6230825 6231135 0.001850915 31.95714286 Hyper-methylatedPCa|NT DMRs chr1 6280441 6283157 0.002765491 −24.67380952Hypo-methylated PCa|NT DMRs chr1 6391527 6392259 0.002291701−22.32440476 Hypo-methylated PCa|NT DMRs chr1 6474659 6479466 1.22E−0920.17793975 Hyper-methylated PCa|NT DMRs chr1 6487398 64876560.007959104 −23.10204082 Hypo-methylated PCa|NT DMRs chr1 65255026526718 0.000205174 43.21428571 Hyper-methylated PCa|NT DMRs chr16569576 6570371 0.00090274  33.7485119 Hyper-methylated PCa|NT DMRs chr16615084 6615539 0.000145094 −31.57222222 Hypo-methylated PCa|NT DMRschr1 6663334 6663683 1.00E−06 22.03007519 Hyper-methylated PCa|NT DMRschr1 6665369 6672507 0.007679542 −32.08095238 Hypo-methylated PCa|NTDMRs chr1 7129988 7130188 0.003742662 22.55904762 Hyper-methylatedPCa|NT DMRs chr1 7154719 7187123 4.24E−10 −26.76927438 Hypo-methylatedPCa|NT DMRs chr1 7281456 7290018 4.45E−08 −25.94126984 Hypo-methylatedPCa|NT DMRs chr1 7393386 7393754 0.000117699 −38.36363636Hypo-methylated PCa|NT DMRs chr1 7496966 7500717 3.18E−06 −23.19467787Hypo-methylated PCa|NT DMRs chr1 7515592 7515823 0.00064571 −47.26530612 Hypo-methylated PCa|NT DMRs chr1 7523160 75232370.005968871 −33.2 Hypo-methylated PCa|NT DMRs chr1 7551243 75515240.004095673 −45.36111111 Hypo-methylated PCa|NT DMRs chr1 75931697593260 0.001969641 −28.16666667 Hypo-methylated PCa|NT DMRs chr17605939 7624371 6.90E−10 −22.0377551 Hypo-methylated PCa|NT DMRs chr17634567 7634752 0.000474737 −55.3015873 Hypo-methylated PCa|NT DMRs chr17669905 7676554 0.000149331 −26.4755102 Hypo-methylated PCa|NT DMRs chr17687895 7690531 0.00010546  −22.39904762 Hypo-methylated PCa|NT DMRschr1 7693634 7696223 2.38E−07 −24.58658009 Hypo-methylated PCa|NT DMRschr1 7923960 7944257 0.000145094 −26.3015873 Hypo-methylated PCa|NT DMRschr1 8065016 8065134 0.008482405 −49.09904762 Hypo-methylated PCa|NTDMRs chr1 8270840 8302412 1.20E−07 26.88635913 Hyper-methylated PCa|NTDMRs chr1 8336576 8343765 6.54E−05 27.20308123 Hyper-methylated PCa|NTDMRs chr1 8389605 8389970 0.000205174 24.78571429 Hyper-methylatedPCa|NT DMRs chr1 8403834 8404051 0.00064571  −62.47278912Hypo-methylated PCa|NT DMRs chr1 8409842 8421025 4.98E−09 −21.11657848Hypo-methylated PCa|NT DMRs chr1 8421680 8433942 0.001582756−35.61754386 Hypo-methylated PCa|NT DMRs chr1 8721541 87456530.000803706 −24.34962406 Hypo-methylated PCa|NT DMRs chr1 89686598968724 0.00023371  39.3 Hyper-methylated PCa|NT DMRs chr1 91244519127247 0.007239577 31.52793651 Hyper-methylated PCa|NT DMRs chr19293230 9293645 1.00E−05 38.64761905 Hyper-methylated PCa|NT DMRs chr19310824 9312074 2.58E−05 −36.94196429 Hypo-methylated PCa|NT DMRs chr19378117 9378377 0.002094   25.04960317 Hyper-methylated PCa|NT DMRs chr19399002 9399325 0.000483473 −37.71854637 Hypo-methylated PCa|NT DMRschr1 9520277 9527533 0.000103673 −45.01011905 Hypo-methylated PCa|NTDMRs chr1 9601503 9621111 1.91E−06 −27.1378882 Hypo-methylated PCa|NTDMRs chr1 9666694 9667637 0.001291665 −32.77705628 Hypo-methylatedPCa|NT DMRs chr1 9688558 9691043 3.06E−06 38.84380952 Hyper-methylatedPCa|NT DMRs chr1 9715244 9715398 0.001969641 39.53333333Hyper-methylated PCa|NT DMRs chr1 9777564 9777967 0.00196964140.07619048 Hyper-methylated PCa|NT DMRs chr1 9909812 99113640.003871035 37.87261905 Hyper-methylated PCa|NT DMRs chr1 99354559935545 0.000377317 −25.625 Hypo-methylated PCa|NT DMRs chr1 1051154510511597 0.000377317 26.43214286 Hyper-methylated PCa|NT DMRs chr110700503 10701575 0.001139334 −26.98928571 Hypo-methylated PCa|NT DMRschr1 10702182 10708045 1.60E−11 −30.99710145 Hypo-methylated PCa|NT DMRschr1 10717177 10724769 4.64E−10 −22.26821572 Hypo-methylated PCa|NT DMRschr1 10732160 10734473 0.002771971 −30.43508772 Hypo-methylated PCa|NTDMRs chr1 10749937 10750080 0.004095673 −46.28571429 Hypo-methylatedPCa|NT DMRs chr1 10776393 10776855 0.005542011 44.98051948Hyper-methylated PCa|NT DMRs chr1 10795360 10795472 0.00543898225.8647619 Hyper-methylated PCa|NT DMRs chr1 10816475 108221150.00044387  −34.77328042 Hypo-methylated PCa|NT DMRs chr1 1083425110843155 0.000753029 −28.68701299 Hypo-methylated PCa|NT DMRs chr110889510 10895896 0.000426728 21.09079365 Hyper-methylated PCa|NT DMRschr1 10909319 10916649 0.002097193 −27.71428571 Hypo-methylated PCa|NTDMRs chr1 10958562 10959556 0.001201396 34.46571429 Hyper-methylatedPCa|NT DMRs chr1 10960174 10961646 0.000376662 −20.27553366Hypo-methylated PCa|NT DMRs chr1 10963986 10965396 2.87E−06 43.06011905Hyper-methylated PCa|NT DMRs chr1 11118847 11119226 6.93E−06−49.33492063 Hypo-methylated PCa|NT DMRs chr1 11323251 113234680.005968871 −33.84761905 Hypo-methylated PCa|NT DMRs chr1 1164573211645979 0.003871035 −20.53373016 Hypo-methylated PCa|NT DMRs chr111714280 11714430 8.62E−05 20.80952381 Hyper-methylated PCa|NT DMRs chr111752120 11752816 6.42E−13 29.48321624 Hyper-methylated PCa|NT DMRs chr111768133 11773620 0.001969641 −20.33469388 Hypo-methylated PCa|NT DMRschr1 11809720 11812628 0.001039378 −20.08791209 Hypo-methylated PCa|NTDMRs chr1 11849426 11851296 0.002437742 −38.38359788 Hypo-methylatedPCa|NT DMRs chr1 11863236 11863430 1.97E−05 20.24285714 Hyper-methylatedPCa|NT DMRs chr1 11919349 11919404 0.000145171 24.8877551Hyper-methylated PCa|NT DMRs chr1 11958191 11958408 4.02E−05 24.63386243Hyper-methylated PCa|NT DMRs chr1 11979113 11979209 0.001969641−49.3952381 Hypo-methylated PCa|NT DMRs chr1 12185599 121862590.000354065 30.15978836 Hyper-methylated PCa|NT DMRs chr1 1220224112226851 0.000703976 20.01578231 Hyper-methylated PCa|NT DMRs chr112227265 12227921 6.08E−15 33.04055829 Hyper-methylated PCa|NT DMRs chr112239199 12240922 0.000205174 36.74089636 Hyper-methylated PCa|NT DMRschr1 12245242 12245615 0.000117699 40.22467532 Hyper-methylated PCa|NTDMRs chr1 12248895 12251890 0.009069241 −27.87012987 Hypo-methylatedPCa|NT DMRs chr1 12655157 12655322 0.000481535 23.71428571Hyper-methylated PCa|NT DMRs chr1 13774065 13789631 0.001836557−32.32967033 Hypo-methylated PCa|NT DMRs chr1 13909632 139097020.000908257 21.67032967 Hyper-methylated PCa|NT DMRs chr1 1422761514228198 1.76E−06 −53.49285714 Hypo-methylated PCa|NT DMRs chr1 1510018515105936 0.002770271 21.63736264 Hyper-methylated PCa|NT DMRs chr115271860 15273458 0.00051204  −45.00952381 Hypo-methylated PCa|NT DMRschr1 15481103 15481562 1.63E−05 37.9 Hyper-methylated PCa|NT DMRs chr115672607 15672976 0.000513415 29.87142857 Hyper-methylated PCa|NT DMRschr1 15711358 15713101 0.001241245 29.48994709 Hyper-methylated PCa|NTDMRs chr1 15738251 15742694 0.002225983 39.50952381 Hyper-methylatedPCa|NT DMRs chr1 15772100 15772171 0.005968871 42.2 Hyper-methylatedPCa|NT DMRs chr1 16124698 16126472 0.00064571  −42.75986395Hypo-methylated PCa|NT DMRs chr1 16163269 16166996 0.00047305932.10666667 Hyper-methylated PCa|NT DMRs chr1 16266065 162686250.001097219 −28.03753501 Hypo-methylated PCa|NT DMRs chr1 1627609216278114 0.000396946 27.61458333 Hyper-methylated PCa|NT DMRs chr116471331 16472685 4.70E−07 −41.0031746 Hypo-methylated PCa|NT DMRs chr116480820 16481019 0.000974795 30.35714286 Hyper-methylated PCa|NT DMRschr1 16488561 16489314 2.17E−07 37.47063492 Hyper-methylated PCa|NT DMRschr1 16542988 16543568 9.66E−07 21.66190476 Hyper-methylated PCa|NT DMRschr1 16553411 16554461 1.60E−19 33.56600733 Hyper-methylated PCa|NT DMRschr1 16638575 16643635 0.000783791 −33.28285714 Hypo-methylated PCa|NTDMRs chr1 16847234 16847864 1.14E−05 26.69382716 Hyper-methylated PCa|NTDMRs chr1 16950871 16951184 0.002534928 −37.63142857 Hypo-methylatedPCa|NT DMRs chr1 16974210 16974916 6.42E−05 27.68677249 Hyper-methylatedPCa|NT DMRs chr1 17305366 17305831 0.000166226 38.36043956Hyper-methylated PCa|NT DMRs chr1 17445283 17445511 5.94E−06 38.74458874Hyper-methylated PCa|NT DMRs chr1 17446145 17448659 0.00517863320.08787879 Hyper-methylated PCa|NT DMRs chr1 17490697 175118360.000688325 −28.99450549 Hypo-methylated PCa|NT DMRs chr1 1771598317719078 0.000226106 −21.07838828 Hypo-methylated PCa|NT DMRs chr117773133 17787034 0.005968871 −29.74166667 Hypo-methylated PCa|NT DMRschr1 17893243 17896312 0.001969641 26.35238095 Hyper-methylated PCa|NTDMRs chr1 17906181 17907373 0.00248539  20.33571429 Hyper-methylatedPCa|NT DMRs chr1 18043398 18043467 0.00064571  −21.89795918Hypo-methylated PCa|NT DMRs chr1 18117942 18127214 8.73E−07 −22.19979296Hypo-methylated PCa|NT DMRs chr1 18348682 18384743 0.007428376−23.71978022 Hypo-methylated PCa|NT DMRs chr1 18482237 18483343 9.81E−07−44.39206349 Hypo-methylated PCa|NT DMRs chr1 18869064 188796130.007526322 25.11833333 Hyper-methylated PCa|NT DMRs chr1 1897685218988808 0.008319869 20.97943723 Hyper-methylated PCa|NT DMRs chr119000796 19002350 6.42E−05 27.48941799 Hyper-methylated PCa|NT DMRs chr119010192 19011587 0.000324616 25.0535014 Hyper-methylated PCa|NT DMRschr1 19144335 19149038 0.000114755 28.72547619 Hyper-methylated PCa|NTDMRs chr1 19201690 19202214 0.000104435 −22.7478458 Hypo-methylatedPCa|NT DMRs chr1 19717467 19717634 0.005968871 50.66190476Hyper-methylated PCa|NT DMRs chr1 19739247 19739501 0.008482405−64.1047619 Hypo-methylated PCa|NT DMRs chr1 20081194 200813410.001969641 −49.8468254 Hypo-methylated PCa|NT DMRs chr1 2049130420495238 1.65E−07 −34.76848073 Hypo-methylated PCa|NT DMRs chr1 2051206420517701 5.31E−06 36.78095238 Hyper-methylated PCa|NT DMRs chr1 2061728320637260 0.000109356 34.33142857 Hyper-methylated PCa|NT DMRs chr121056502 21058361 4.40E−10 29.44976959 Hyper-methylated PCa|NT DMRs chr121589014 21595186 4.69E−05 −23.76890756 Hypo-methylated PCa|NT DMRs chr121652411 21652493 0.005968871 41.48571429 Hyper-methylated PCa|NT DMRschr1 21860580 21861981 0.00641359  −28.11904762 Hypo-methylated PCa|NTDMRs chr1 21864320 21865088 1.52E−06 31.16507937 Hyper-methylated PCa|NTDMRs chr1 21877537 21877782 0.000205174 −35.13888889 Hypo-methylatedPCa|NT DMRs chr1 21950270 21953521 0.000168936 −35.44805195Hypo-methylated PCa|NT DMRs chr1 21960463 21966546 0.002285803−26.07428571 Hypo-methylated PCa|NT DMRs chr1 21978653 219792880.001394173 26.67176871 Hyper-methylated PCa|NT DMRs chr1 2214987922152072 0.002856529 23.73154762 Hyper-methylated PCa|NT DMRs chr122350910 22351261 7.95E−05 23.02930403 Hyper-methylated PCa|NT DMRs chr122535198 22535512 0.007679542 23.78306878 Hyper-methylated PCa|NT DMRschr1 22576056 22586332 2.43E−07 −43.89691877 Hypo-methylated PCa|NT DMRschr1 22614808 22624308 0.001684481 23.85510204 Hyper-methylated PCa|NTDMRs chr1 22909639 22915043 0.000392715 −21.06809524 Hypo-methylatedPCa|NT DMRs chr1 22927298 22927533 0.00753722  −24.31868132Hypo-methylated PCa|NT DMRs chr1 22944642 22944694 0.000205174−29.91071429 Hypo-methylated PCa|NT DMRs chr1 22946418 229530220.007679542 25.57936508 Hyper-methylated PCa|NT DMRs chr1 2327981723280300 2.19E−23 33.84963112 Hyper-methylated PCa|NT DMRs chr1 2380552123805874 0.004095673 −55.83333333 Hypo-methylated PCa|NT DMRs chr123880455 23881057 0.00216533  30.125 Hyper-methylated PCa|NT DMRs chr123918816 23928152 0.005968871 22.87142857 Hyper-methylated PCa|NT DMRschr1 24120771 24124208 0.000200037 −28.63533835 Hypo-methylated PCa|NTDMRs chr1 24127957 24128033 8.73E−05 −37.30612245 Hypo-methylated PCa|NTDMRs chr1 24743847 24744307 0.005968871 −43.1047619 Hypo-methylatedPCa|NT DMRs chr1 24967334 24968562 0.00026034  23.03571429Hyper-methylated PCa|NT DMRs chr1 25196356 25198876 5.87E−08 45.31738095Hyper-methylated PCa|NT DMRs chr1 25327826 25328022 0.00543898226.78571429 Hyper-methylated PCa|NT DMRs chr1 25346057 253491150.008581782 33.56547619 Hyper-methylated PCa|NT DMRs chr1 2556811925572539 0.00068166  −45.07738095 Hypo-methylated PCa|NT DMRs chr125882610 25890156 9.62E−05 21.5764881 Hyper-methylated PCa|NT DMRs chr125894889 25895652 6.42E−05 −55.24338624 Hypo-methylated PCa|NT DMRs chr125944228 25944662 9.07E−08 22.14285714 Hyper-methylated PCa|NT DMRs chr126075447 26075643 0.005968871 −44.8 Hypo-methylated PCa|NT DMRs chr126202251 26202628 1.70E−11 22.82014652 Hyper-methylated PCa|NT DMRs chr126317172 26319385 0.003587573 22.26493506 Hyper-methylated PCa|NT DMRschr1 26372021 26372155 0.005375157 20.13265306 Hyper-methylated PCa|NTDMRs chr1 26481932 26482761 0.001241245 27.58730159 Hyper-methylatedPCa|NT DMRs chr1 26503847 26504147 4.45E−08 −21.9352381 Hypo-methylatedPCa|NT DMRs chr1 26614241 26617546 2.86E−05 51.36190476 Hyper-methylatedPCa|NT DMRs chr1 26645629 26645803 0.005968871 33.88571429Hyper-methylated PCa|NT DMRs chr1 26671747 26684107 0.000822388−21.46513057 Hypo-methylated PCa|NT DMRs chr1 26687175 26687430 5.94E−0620.11255411 Hyper-methylated PCa|NT DMRs chr1 26848240 268484500.001969641 −21.7014652 Hypo-methylated PCa|NT DMRs chr1 2713167127131723 0.001969641 42.61904762 Hyper-methylated PCa|NT DMRs chr127338911 27339194 0.000207281 29.16135531 Hyper-methylated PCa|NT DMRschr1 27687140 27687696 2.45E−16 47.72445055 Hyper-methylated PCa|NT DMRschr1 27729855 27730377 5.52E−05 33.27229437 Hyper-methylated PCa|NT DMRschr1 27840125 27840800 0.001480644 32.49952381 Hyper-methylated PCa|NTDMRs chr1 27846977 27848263 0.007338757 43.20535714 Hyper-methylatedPCa|NT DMRs chr1 27882335 27882652 0.006466965 30.18367347Hyper-methylated PCa|NT DMRs chr1 27923968 27925971 0.00196964140.27619048 Hyper-methylated PCa|NT DMRs chr1 27939500 279417830.000981814 −24.03961905 Hypo-methylated PCa|NT DMRs chr1 2801324728013387 0.001969641 −40.35714286 Hypo-methylated PCa|NT DMRs chr128195587 28197508 0.009407512 32.57142857 Hyper-methylated PCa|NT DMRschr1 28500721 28501881 0.00064571  23.29591837 Hyper-methylated PCa|NTDMRs chr1 29075805 29075853 0.005968871 41.42857143 Hyper-methylatedPCa|NT DMRs chr1 29139076 29139838 0.005433534 −30.9047619Hypo-methylated PCa|NT DMRs chr1 29189987 29197088 0.000491935−22.88756614 Hypo-methylated PCa|NT DMRs chr1 29460830 29461328 2.17E−1225.55703212 Hyper-methylated PCa|NT DMRs chr1 29657461 29708397 9.63E−06−25.73958333 Hypo-methylated PCa|NT DMRs chr1 29721179 29763815 7.09E−05−22.65303777 Hypo-methylated PCa|NT DMRs chr1 29869374 298777600.000188647 −27.52877847 Hypo-methylated PCa|NT DMRs chr1 3025962030301673 7.06E−08 −27.06077098 Hypo-methylated PCa|NT DMRs chr1 3037217930375353 0.003192753 −20.29391534 Hypo-methylated PCa|NT DMRs chr130424950 30444639 0.00064571  −30.02721088 Hypo-methylated PCa|NT DMRschr1 30515011 30538636 5.95E−08 −22.51490015 Hypo-methylated PCa|NT DMRschr1 30573155 30574847 0.000509286 −25.13784461 Hypo-methylated PCa|NTDMRs chr1 30587658 30705290 2.34E−06 −27.11693122 Hypo-methylated PCa|NTDMRs chr1 30720474 30776141 1.07E−09 −24.58324515 Hypo-methylated PCa|NTDMRs chr1 30798832 30802077 0.000196301 −27.76785714 Hypo-methylatedPCa|NT DMRs chr1 30911320 30937802 0.002585277 −35.15119048Hypo-methylated PCa|NT DMRs chr1 31278174 31280213 0.00178986720.00291005 Hyper-methylated PCa|NT DMRs chr1 31380703 31381102 7.12E−0622.21256614 Hyper-methylated PCa|NT DMRs chr1 31989683 32003965 4.78E−0527.38738095 Hyper-methylated PCa|NT DMRs chr1 32013367 320143740.007560755 −29.82202381 Hypo-methylated PCa|NT DMRs chr1 3205262832052681 0.00023371  20.6547619 Hyper-methylated PCa|NT DMRs chr132281534 32281723 0.005513661 −27.69642857 Hypo-methylated PCa|NT DMRschr1 32666528 32666956 0.001969641 26.86734694 Hyper-methylated PCa|NTDMRs chr1 32788165 32788585 0.005968871 −49.35238095 Hypo-methylatedPCa|NT DMRs chr1 33390500 33391874 1.36E−05 35.76742857 Hyper-methylatedPCa|NT DMRs chr1 33928344 33938451 6.59E−10 32.87727891 Hyper-methylatedPCa|NT DMRs chr1 34628316 34628578 0.000377317 26.22916667Hyper-methylated PCa|NT DMRs chr1 34660621 34834336 1.17E−06−25.03770914 Hypo-methylated PCa|NT DMRs chr1 34913158 34973225 7.31E−05−35.01156463 Hypo-methylated PCa|NT DMRs chr1 35116130 35116544 3.66E−05−29.70047619 Hypo-methylated PCa|NT DMRs chr1 35395855 353964610.002111644 21.06043956 Hyper-methylated PCa|NT DMRs chr1 3602884936029016 0.005968871 50.6 Hyper-methylated PCa|NT DMRs chr1 3656335336563519 0.000176046 −23.07792208 Hypo-methylated PCa|NT DMRs chr136643764 36644433 4.29E−11 −27.20013605 Hypo-methylated PCa|NT DMRs chr136832075 36832397 0.001969641 47.33730159 Hyper-methylated PCa|NT DMRschr1 36866393 36866855 0.003448944 28.63265306 Hyper-methylated PCa|NTDMRs chr1 36948313 36952573 6.90E−05 33.88015873 Hyper-methylated PCa|NTDMRs chr1 36977709 37027135 2.06E−07 −23.58852259 Hypo-methylated PCa|NTDMRs chr1 37055832 37177594 6.88E−11 −27.80623742 Hypo-methylated PCa|NTDMRs chr1 37195966 37196023 0.003622801 20.76190476 Hyper-methylatedPCa|NT DMRs chr1 37204419 37240015 1.57E−05 −24.03588435 Hypo-methylatedPCa|NT DMRs chr1 37266622 37307972 1.27E−08 −31.32891156 Hypo-methylatedPCa|NT DMRs chr1 37333487 37351798 8.79E−06 −30.71325052 Hypo-methylatedPCa|NT DMRs chr1 37357777 37447866 1.00E−06 −32.3287619 Hypo-methylatedPCa|NT DMRs chr1 37448535 37476265 9.00E−07 −31.45349206 Hypo-methylatedPCa|NT DMRs chr1 37549295 37561037 8.31E−07 −31.76825397 Hypo-methylatedPCa|NT DMRs chr1 37579229 37645899 6.68E−07 −29.70617284 Hypo-methylatedPCa|NT DMRs chr1 37735318 37756489 0.004149771 −27.89304029Hypo-methylated PCa|NT DMRs chr1 38192490 38201159 3.09E−06 33.65465839Hyper-methylated PCa|NT DMRs chr1 38679372 38679582 0.00596887134.05714286 Hyper-methylated PCa|NT DMRs chr1 38757788 38758397 6.80E−0623.14264069 Hyper-methylated PCa|NT DMRs chr1 39025055 39025301 1.41E−0536.3085034 Hyper-methylated PCa|NT DMRs chr1 39090142 39152455 9.84E−05−21.01117216 Hypo-methylated PCa|NT DMRs chr1 39281980 39283694 1.77E−0834.92922824 Hyper-methylated PCa|NT DMRs chr1 39407394 394077700.000481535 −56.42857143 Hypo-methylated PCa|NT DMRs chr1 3954664039546835 2.75E−05 26.16772487 Hyper-methylated PCa|NT DMRs chr1 3995773339958610 0.000468139 23.11904762 Hyper-methylated PCa|NT DMRs chr139974878 39976077 0.003056323 33.98148148 Hyper-methylated PCa|NT DMRschr1 40075380 40075810 0.000241095 28.01503759 Hyper-methylated PCa|NTDMRs chr1 40137907 40149874 3.62E−06 24.5981417 Hyper-methylated PCa|NTDMRs chr1 40253709 40253793 1.67E−05 36.08055556 Hyper-methylated PCa|NTDMRs chr1 40268333 40269945 0.001969641 53.58174603 Hyper-methylatedPCa|NT DMRs chr1 40780274 40782303 3.73E−11 27.26190476 Hyper-methylatedPCa|NT DMRs chr1 41283622 41284920 6.78E−07 34.73370927 Hyper-methylatedPCa|NT DMRs chr1 41898163 41898446 0.000205174 −51.39285714Hypo-methylated PCa|NT DMRs chr1 41901398 41901695 0.00068166 24.84583333 Hyper-methylated PCa|NT DMRs chr1 41947940 419482190.000481535 −37.83862434 Hypo-methylated PCa|NT DMRs chr1 4219278942207041 2.20E−06 38.9962963 Hyper-methylated PCa|NT DMRs chr1 4238590142386064 0.005968871 38.34285714 Hyper-methylated PCa|NT DMRs chr142611494 42611607 3.05E−06 27.91208791 Hyper-methylated PCa|NT DMRs chr143250855 43251202 3.25E−10 44.5270936 Hyper-methylated PCa|NT DMRs chr143504955 43505044 0.00064571  −49.35714286 Hypo-methylated PCa|NT DMRschr1 43701705 43701956 0.005968871 −49.57333333 Hypo-methylated PCa|NTDMRs chr1 43751201 43751567 0.00064571  −40.89795918 Hypo-methylatedPCa|NT DMRs chr1 43807789 43814894 1.19E−11 −46.31965552 Hypo-methylatedPCa|NT DMRs chr1 43832025 43832327 0.000974795 −40.16785714Hypo-methylated PCa|NT DMRs chr1 44031123 44031886 4.41E−16 38.34957599Hyper-methylated PCa|NT DMRs chr1 44070591 44070757 0.005968871−42.82857143 Hypo-methylated PCa|NT DMRs chr1 44688915 447042140.00013079  36.73483709 Hyper-methylated PCa|NT DMRs chr1 4487284444883781 1.01E−40 25.70754778 Hyper-methylated PCa|NT DMRs chr1 4512604945126289 0.000215808 −38.36984127 Hypo-methylated PCa|NT DMRs chr145267318 45267589 0.000481535 29.74603175 Hyper-methylated PCa|NT DMRschr1 45285916 45286086 1.42E−05 40.87755102 Hyper-methylated PCa|NT DMRschr1 46770707 46771105 0.000836132 −25.76719577 Hypo-methylated PCa|NTDMRs chr1 46950611 46954881 1.62E−09 23.34227642 Hyper-methylated PCa|NTDMRs chr1 48246486 48247190 1.97E−05 −31.61666667 Hypo-methylated PCa|NTDMRs chr1 48353253 48353639 0.00068166  39.3077381 Hyper-methylatedPCa|NT DMRs chr1 48462240 48462616 7.74E−05 30.82783883 Hyper-methylatedPCa|NT DMRs chr1 48555659 48564977 0.00641359  −40.68095238Hypo-methylated PCa|NT DMRs chr1 49038737 49038934 0.005968871−31.4952381 Hypo-methylated PCa|NT DMRs chr1 50893272 50898796 1.81E−0721.31452381 Hyper-methylated PCa|NT DMRs chr1 51498730 515247430.002767976 −38.76406926 Hypo-methylated PCa|NT DMRs chr1 5179544351795600 0.005968871 −49.25714286 Hypo-methylated PCa|NT DMRs chr152194940 52195821 6.68E−21 24.93141321 Hyper-methylated PCa|NT DMRs chr153067881 53068491 2.16E−33 25.51680672 Hyper-methylated PCa|NT DMRs chr153184149 53187506 0.00068166  −22.06845238 Hypo-methylated PCa|NT DMRschr1 53308824 53309451 2.83E−09 21.30588235 Hyper-methylated PCa|NT DMRschr1 53858321 53866663 1.20E−07 −22.76870748 Hypo-methylated PCa|NT DMRschr1 53925973 53926473 8.63E−05 −23.81873016 Hypo-methylated PCa|NT DMRschr1 53966544 53969330 0.000632596 −29.26041667 Hypo-methylated PCa|NTDMRs chr1 53992290 53994306 1.66E−05 −50.09803922 Hypo-methylated PCa|NTDMRs chr1 54040624 54041031 0.00064571  48.9829932 Hyper-methylatedPCa|NT DMRs chr1 54868836 54869222 0.003809353 −24.70380952Hypo-methylated PCa|NT DMRs chr1 54940393 54944221 3.09E−09 25.03543956Hyper-methylated PCa|NT DMRs chr1 54951712 54953651 9.63E−06 25.95646259Hyper-methylated PCa|NT DMRs chr1 54965564 54965767 0.00097479520.90297619 Hyper-methylated PCa|NT DMRs chr1 54979765 54980174 5.28E−05−28.51465201 Hypo-methylated PCa|NT DMRs chr1 55008127 550087220.00025701  25.99285714 Hyper-methylated PCa|NT DMRs chr1 5548143655487895 0.005968871 −27.59077381 Hypo-methylated PCa|NT DMRs chr155513794 55516110 0.005513661 −35.95646259 Hypo-methylated PCa|NT DMRschr1 57285156 57285279 0.005968871 −45.05619048 Hypo-methylated PCa|NTDMRs chr1 58715050 58716179 1.18E−20 24.64002761 Hyper-methylated PCa|NTDMRs chr1 59280256 59280466 6.67E−10 −31.71683673 Hypo-methylated PCa|NTDMRs chr1 59314696 59315051 0.001969641 −34.42063492 Hypo-methylatedPCa|NT DMRs chr1 61509159 61509282 8.73E−07 23.39855072 Hyper-methylatedPCa|NT DMRs chr1 61608446 61649974 0.005513661 −51.59285714Hypo-methylated PCa|NT DMRs chr1 62793453 62793591 0.00064571 −39.69387755 Hypo-methylated PCa|NT DMRs chr1 63234270 632344750.005968871 −57.48571429 Hypo-methylated PCa|NT DMRs chr1 6473135464784318 0.000176046 −37.07705628 Hypo-methylated PCa|NT DMRs chr168038066 68048485 0.00179283  −33.51071429 Hypo-methylated PCa|NT DMRschr1 68759638 68759826 0.005968871 22.25714286 Hyper-methylated PCa|NTDMRs chr1 72542872 72697809 3.50E−05 −31.5970696 Hypo-methylated PCa|NTDMRs chr1 73092518 73115350 6.22E−05 −21.78877551 Hypo-methylated PCa|NTDMRs chr1 73764404 74251998 2.59E−08 −29.52310406 Hypo-methylated PCa|NTDMRs chr1 74311953 74663681 0.00284639  −24.21942857 Hypo-methylatedPCa|NT DMRs chr1 74754290 75159093 7.08E−13 −34.67160827 Hypo-methylatedPCa|NT DMRs chr1 75297758 75579832 4.90E−08 −34.45238095 Hypo-methylatedPCa|NT DMRs chr1 75616628 75687737 0.001789867 −25.23439153Hypo-methylated PCa|NT DMRs chr1 76354705 76537546 0.002585277 −34.8625Hypo-methylated PCa|NT DMRs chr1 76540513 76540541 0.00848240526.74285714 Hyper-methylated PCa|NT DMRs chr1 77230619 772308370.000215808 23.01587302 Hyper-methylated PCa|NT DMRs chr1 7733413377335031 1.33E−10 33.43320106 Hyper-methylated PCa|NT DMRs chr1 7774860377748806 0.00064571  23.68707483 Hyper-methylated PCa|NT DMRs chr178140160 78147476 0.005685503 −21.96428571 Hypo-methylated PCa|NT DMRschr1 78153343 78153404 0.001969641 26.26190476 Hyper-methylated PCa|NTDMRs chr1 78442913 78443067 0.001969641 −37.66666667 Hypo-methylatedPCa|NT DMRs chr1 79982865 79982913 0.005968871 −41.28571429Hypo-methylated PCa|NT DMRs chr1 81674230 81674454 0.00409567349.14285714 Hyper-methylated PCa|NT DMRs chr1 81990947 819910720.005968871 −43.51428571 Hypo-methylated PCa|NT DMRs chr1 8546331485463954 9.14E−09 23.12169312 Hyper-methylated PCa|NT DMRs chr1 8759800387598464 1.21E−08 34.14327731 Hyper-methylated PCa|NT DMRs chr1 8767897387767837 8.48E−11 −31.62565284 Hypo-methylated PCa|NT DMRs chr1 9030930890309965 2.69E−05 37.08067227 Hyper-methylated PCa|NT DMRs chr1 9169226691703074 0.001667552 −38.41798942 Hypo-methylated PCa|NT DMRs chr192690657 92695075 0.000205174 −29.90654762 Hypo-methylated PCa|NT DMRschr1 93251203 93251698 0.008581782 −29.2952381 Hypo-methylated PCa|NTDMRs chr1 94146663 94146876 3.01E−07 31.35285714 Hyper-methylated PCa|NTDMRs chr1 94159729 94206975 0.000157376 −21.36895238 Hypo-methylatedPCa|NT DMRs chr1 95391231 95391315 0.000481535 25.50793651Hyper-methylated PCa|NT DMRs chr1 95392642 95393462 1.47E−15 29.28767007Hyper-methylated PCa|NT DMRs chr1 96421395 96616472 9.89E−08−30.47505669 Hypo-methylated PCa|NT DMRs chr1 98352882 983711340.000974795 −27.55059524 Hypo-methylated PCa|NT DMRs chr1 9900686399089943 0.000974795 −41.83988095 Hypo-methylated PCa|NT DMRs chr199247365 99439568 4.33E−05 −37.05164835 Hypo-methylated PCa|NT DMRs chr199478270 99544615 5.79E−09 −35.16190476 Hypo-methylated PCa|NT DMRs chr1102694337 103042273 1.23E−05 −32.48385093 Hypo-methylated PCa|NT DMRschr1 104434280 104616514 1.64E−13 −34.23446712 Hypo-methylated PCa|NTDMRs chr1 104695970 105142681 1.96E−22 −31.12258503 Hypo-methylatedPCa|NT DMRs chr1 108023308 108023483 0.000974795 39.51785714Hyper-methylated PCa|NT DMRs chr1 109655734 109655971 0.00057057626.84391534 Hyper-methylated PCa|NT DMRs chr1 109783324 1097836510.002534928 −26.1 Hypo-methylated PCa|NT DMRs chr1 109806825 1098068960.000205174 −37.97321429 Hypo-methylated PCa|NT DMRs chr1 110009924110010025 0.000861954 27.30753968 Hyper-methylated PCa|NT DMRs chr1110086450 110086987 0.00355142  −24.56776557 Hypo-methylated PCa|NT DMRschr1 110166638 110167153 3.61E−05 37.19795918 Hyper-methylated PCa|NTDMRs chr1 110254680 110254776 0.001076343 30.45887446 Hyper-methylatedPCa|NT DMRs chr1 110395903 110396099 0.004057568 33.1984127Hyper-methylated PCa|NT DMRs chr1 110672715 110673214 8.23E−0834.18024691 Hyper-methylated PCa|NT DMRs chr1 110754054 1107548722.89E−13 24.75137255 Hyper-methylated PCa|NT DMRs chr1 112016297112016636 0.000822388 44.18285714 Hyper-methylated PCa|NT DMRs chr1112058195 112058444 9.30E−06 30.83035714 Hyper-methylated PCa|NT DMRschr1 112504962 112508570 0.007679542 31.36349206 Hyper-methylated PCa|NTDMRs chr1 112933091 112933235 0.00064571  −40.40816327 Hypo-methylatedPCa|NT DMRs chr1 113181278 113184418 0.000836132 −28.28835979Hypo-methylated PCa|NT DMRs chr1 113265661 113265809 4.90E−0844.11580087 Hyper-methylated PCa|NT DMRs chr1 113397255 1133973020.005968871 25.87904762 Hyper-methylated PCa|NT DMRs chr1 115231628115238458 0.001241245 −23.48412698 Hypo-methylated PCa|NT DMRs chr1115333233 115333495 0.000547122 −23.1697479 Hypo-methylated PCa|NT DMRschr1 115880730 115881506 1.95E−05 26.65958188 Hyper-methylated PCa|NTDMRs chr1 116004434 116088091 0.000261152 −27.06819728 Hypo-methylatedPCa|NT DMRs chr1 116666737 116666937 0.005968871 −57.54285714Hypo-methylated PCa|NT DMRs chr1 116710405 116770527 8.97E−0934.10348432 Hyper-methylated PCa|NT DMRs chr1 116918436 1169188330.00064571  −39.19727891 Hypo-methylated PCa|NT DMRs chr1 117156409117156642 2.86E−05 −26.31135531 Hypo-methylated PCa|NT DMRs chr1117283501 117299914 0.005968871 25.24761905 Hyper-methylated PCa|NT DMRschr1 118114942 118115242 0.005513661 −36.26964286 Hypo-methylated PCa|NTDMRs chr1 119870029 119870803 3.56E−08 38.3638448 Hyper-methylatedPCa|NT DMRs chr1 120166206 120168799 0.000190021 −37.7952381Hypo-methylated PCa|NT DMRs chr1 120436834 120437114 0.00233547728.12244898 Hyper-methylated PCa|NT DMRs chr1 120906320 1209063550.005968871 −55.17142857 Hypo-methylated PCa|NT DMRs chr1 143663862143664368 3.66E−05 25.75809524 Hyper-methylated PCa|NT DMRs chr1147295926 147301218 0.001969641 −22.42857143 Hypo-methylated PCa|NT DMRschr1 147718179 147718760 0.004553481 26.62539683 Hyper-methylated PCa|NTDMRs chr1 147825907 147826178 3.87E−05 30.8977591 Hyper-methylatedPCa|NT DMRs chr1 148891082 148897613 0.00046742  −35.35714286Hypo-methylated PCa|NT DMRs chr1 149162565 149180525 0.001181579−23.4010989 Hypo-methylated PCa|NT DMRs chr1 149197879 1492227890.000143323 −24.5475 Hypo-methylated PCa|NT DMRs chr1 149231293149284147 0.001758998 −22.49174603 Hypo-methylated PCa|NT DMRs chr1149672605 149672888 0.001969641 45.26190476 Hyper-methylated PCa|NT DMRschr1 149712217 149719537 2.85E−06 29.41493506 Hyper-methylated PCa|NTDMRs chr1 150134720 150135088 0.005968871 44.14285714 Hyper-methylatedPCa|NT DMRs chr1 150516925 150519680 0.004095673 −39.56349206Hypo-methylated PCa|NT DMRs chr1 150523439 150525535 0.00417850625.53690476 Hyper-methylated PCa|NT DMRs chr1 150897012 1508980780.005243408 23.54652015 Hyper-methylated PCa|NT DMRs chr1 150947666150951875 1.75E−05 28.9225 Hyper-methylated PCa|NT DMRs chr1 151482593151483096 0.000556452 −29.06972789 Hypo-methylated PCa|NT DMRs chr1151675661 151676614 0.001216085 26.21148459 Hyper-methylated PCa|NT DMRschr1 151773258 151773306 0.005968871 36.17142857 Hyper-methylated PCa|NTDMRs chr1 152051042 152073000 7.14E−06 −23.12014652 Hypo-methylatedPCa|NT DMRs chr1 152506528 153195799 1.31E−14 −31.33899749Hypo-methylated PCa|NT DMRs chr1 153312923 153327231 2.29E−06−32.85661376 Hypo-methylated PCa|NT DMRs chr1 153670233 1536708468.31E−07 41.16517857 Hyper-methylated PCa|NT DMRs chr1 153761958153762187 0.003809353 −23.62619048 Hypo-methylated PCa|NT DMRs chr1153762201 153762518 0.001181579 26.14285714 Hyper-methylated PCa|NT DMRschr1 154166483 154172333 0.007560755 −33.66785714 Hypo-methylated PCa|NTDMRs chr1 154475135 154475936 3.45E−05 20.95887446 Hyper-methylatedPCa|NT DMRs chr1 154681606 154685576 0.000377317 −21.08035714Hypo-methylated PCa|NT DMRs chr1 154786156 154786338 0.005968871−46.28571429 Hypo-methylated PCa|NT DMRs chr1 154808682 1548111150.003464153 −28.48484848 Hypo-methylated PCa|NT DMRs chr1 154843162154851481 0.005618668 −23.1026455 Hypo-methylated PCa|NT DMRs chr1154971110 154971872 0.000117699 30.00865801 Hyper-methylated PCa|NT DMRschr1 155097713 155098952 1.15E−07 −33.830839 Hypo-methylated PCa|NT DMRschr1 155220243 155224084 1.43E−06 36.72380952 Hyper-methylated PCa|NTDMRs chr1 155264329 155265468 1.72E−09 22.63065057 Hyper-methylatedPCa|NT DMRs chr1 155290759 155291206 0.002994094 31.995671Hyper-methylated PCa|NT DMRs chr1 155892560 155903223 0.006225823−34.0004329 Hypo-methylated PCa|NT DMRs chr1 156046344 1560468642.49E−12 40.87116402 Hyper-methylated PCa|NT DMRs chr1 156051240156051524 8.90E−07 26.91428571 Hyper-methylated PCa|NT DMRs chr1156211434 156211494 0.001115302 25.87857143 Hyper-methylated PCa|NT DMRschr1 156255142 156256264 7.92E−06 −41.5837535 Hypo-methylated PCa|NTDMRs chr1 156405371 156405689 1.50E−08 29.13238095 Hyper-methylatedPCa|NT DMRs chr1 156661102 156662023 0.000609882 37.06349206Hyper-methylated PCa|NT DMRs chr1 156713538 156715050 3.05E−0626.82857143 Hyper-methylated PCa|NT DMRs chr1 156785879 1567866890.009807302 27.53142857 Hyper-methylated PCa|NT DMRs chr1 156813949156821140 3.06E−05 33.23579639 Hyper-methylated PCa|NT DMRs chr1157258369 157346444 9.43E−05 −25.6996337 Hypo-methylated PCa|NT DMRschr1 158083971 158085900 0.000132887 −35.50952381 Hypo-methylated PCa|NTDMRs chr1 158098549 158118900 0.002097193 −37.64285714 Hypo-methylatedPCa|NT DMRs chr1 160347295 160365196 0.000215808 −22.61428571Hypo-methylated PCa|NT DMRs chr1 160376813 160582932 5.60E−12−28.73435374 Hypo-methylated PCa|NT DMRs chr1 160751831 1607605290.004659837 −28.05952381 Hypo-methylated PCa|NT DMRs chr1 161035517161039594 0.000145171 54.42278912 Hyper-methylated PCa|NT DMRs chr1161103733 161104036 0.009106413 −37.47619048 Hypo-methylated PCa|NT DMRschr1 161167870 161168394 1.71E−05 −31.74461153 Hypo-methylated PCa|NTDMRs chr1 161585585 161586729 1.87E−05 −22.07936508 Hypo-methylatedPCa|NT DMRs chr1 161591532 161592118 3.11E−05 21.7010582Hyper-methylated PCa|NT DMRs chr1 164669296 164681798 0.00019630133.69920635 Hyper-methylated PCa|NT DMRs chr1 165325913 1653263143.10E−05 29.27731092 Hyper-methylated PCa|NT DMRs chr1 165913078166002328 2.86E−07 −40 Hypo-methylated PCa|NT DMRs chr1 166853374166853813 5.25E−10 25.49768707 Hyper-methylated PCa|NT DMRs chr1166998500 166999070 0.000136862 −24.92698413 Hypo-methylated PCa|NT DMRschr1 167094887 167095593 0.001969641 −52.65 Hypo-methylated PCa|NT DMRschr1 167498532 167498592 0.005968871 −35.71428571 Hypo-methylated PCa|NTDMRs chr1 167572289 167572355 0.008482405 56.51428571 Hyper-methylatedPCa|NT DMRs chr1 168302983 168399471 0.001241245 −33.53703704Hypo-methylated PCa|NT DMRs chr1 170082030 170500398 3.79E−08−32.20819491 Hypo-methylated PCa|NT DMRs chr1 170749435 1708266810.000114755 −31.91941392 Hypo-methylated PCa|NT DMRs chr1 173854852173854985 0.001969641 44.11904762 Hyper-methylated PCa|NT DMRs chr1175037023 175048874 2.05E−13 −23.65551684 Hypo-methylated PCa|NT DMRschr1 175338190 175463492 1.07E−13 −23.52293763 Hypo-methylated PCa|NTDMRs chr1 178482861 178483003 0.001969641 −55.57142857 Hypo-methylatedPCa|NT DMRs chr1 179264999 179265029 0.008482405 −29.96666667Hypo-methylated PCa|NT DMRs chr1 179334235 179334537 0.003391914−33.88941799 Hypo-methylated PCa|NT DMRs chr1 179922654 1799227030.005968871 34.05619048 Hyper-methylated PCa|NT DMRs chr1 180176488180182756 0.003892841 32.19047619 Hyper-methylated PCa|NT DMRs chr1180202396 180203116 3.00E−19 20.76048237 Hyper-methylated PCa|NT DMRschr1 180882232 180882453 5.75E−09 26.85714286 Hyper-methylated PCa|NTDMRs chr1 181073954 181074190 9.10E−08 23.17573696 Hyper-methylatedPCa|NT DMRs chr1 181097831 181101599 0.004149771 34.07032967Hyper-methylated PCa|NT DMRs chr1 181803019 181944036 0.001969641−36.78730159 Hypo-methylated PCa|NT DMRs chr1 182025773 1820265627.84E−08 24.21269841 Hyper-methylated PCa|NT DMRs chr1 182310800182316426 0.001969641 −36.71825397 Hypo-methylated PCa|NT DMRs chr1183386275 183386606 3.87E−08 26.57769424 Hyper-methylated PCa|NT DMRschr1 184005493 184006015 4.11E−07 25.9037594 Hyper-methylated PCa|NTDMRs chr1 184618881 184639635 0.004711566 33.57983193 Hyper-methylatedPCa|NT DMRs chr1 185663114 185663347 0.002097193 31.88435374Hyper-methylated PCa|NT DMRs chr1 185721185 186230991 5.84E−05−47.35039683 Hypo-methylated PCa|NT DMRs chr1 186649692 1866499865.83E−05 33.42857143 Hyper-methylated PCa|NT DMRs chr1 189063671189109551 2.24E−08 −22.41005291 Hypo-methylated PCa|NT DMRs chr1189469044 189509725 0.000783791 −24.51857143 Hypo-methylated PCa|NT DMRschr1 190761371 190994247 6.41E−10 −35.75697865 Hypo-methylated PCa|NTDMRs chr1 193253015 193253150 0.005968871 −37.67428571 Hypo-methylatedPCa|NT DMRs chr1 194312007 195888354 1.83E−50 −34.29199485Hypo-methylated PCa|NT DMRs chr1 196115710 196537618 4.50E−08−35.59504762 Hypo-methylated PCa|NT DMRs chr1 196611329 1968440685.19E−07 −38.29 Hypo-methylated PCa|NT DMRs chr1 196932515 1970383591.67E−07 −29.35119048 Hypo-methylated PCa|NT DMRs chr1 197304856197324767 1.76E−06 −32.02380952 Hypo-methylated PCa|NT DMRs chr1197946957 197963991 0.000205174 −38.80357143 Hypo-methylated PCa|NT DMRschr1 200003048 200008049 2.24E−14 30.85496368 Hyper-methylated PCa|NTDMRs chr1 200456599 200482173 7.87E−05 −40.63053221 Hypo-methylatedPCa|NT DMRs chr1 200842697 200843427 1.80E−13 32.76537967Hyper-methylated PCa|NT DMRs chr1 201154172 201175371 0.0078067 −23.11764706 Hypo-methylated PCa|NT DMRs chr1 201228945 2012291650.001969641 52.64285714 Hyper-methylated PCa|NT DMRs chr1 201244318201244536 0.000957078 −27.72727273 Hypo-methylated PCa|NT DMRs chr1201252201 201253432 1.99E−11 27.24743231 Hyper-methylated PCa|NT DMRschr1 201709358 201710008 1.30E−10 28.24039939 Hyper-methylated PCa|NTDMRs chr1 201858339 201858839 0.00512564  22.98280423 Hyper-methylatedPCa|NT DMRs chr1 202091944 202092296 0.000205174 −58 Hypo-methylatedPCa|NT DMRs chr1 202125897 202132435 3.02E−07 42.0474026Hyper-methylated PCa|NT DMRs chr1 202168301 202168650 0.00064571 40.96598639 Hyper-methylated PCa|NT DMRs chr1 202210873 2022111940.001969641 34.45238095 Hyper-methylated PCa|NT DMRs chr1 202614001202614128 0.001969641 49.1547619 Hyper-methylated PCa|NT DMRs chr1202772807 202772872 0.005968871 35.51428571 Hyper-methylated PCa|NT DMRschr1 203184087 203186963 0.005513661 26.46428571 Hyper-methylated PCa|NTDMRs chr1 203242717 203243001 0.003448944 33.66326531 Hyper-methylatedPCa|NT DMRs chr1 203281669 203282013 0.005006723 25.26428571Hyper-methylated PCa|NT DMRs chr1 203457686 203477847 0.002562638−20.35674603 Hypo-methylated PCa|NT DMRs chr1 203595061 2035988001.75E−11 27.75462963 Hyper-methylated PCa|NT DMRs chr1 203695223203731459 7.79E−05 −21.39285714 Hypo-methylated PCa|NT DMRs chr1204056651 204073611 0.001899053 −33.63865546 Hypo-methylated PCa|NT DMRschr1 204165654 204165825 0.002094   −28.57380952 Hypo-methylated PCa|NTDMRs chr1 204300954 204301279 0.002097193 −37.32653061 Hypo-methylatedPCa|NT DMRs chr1 204348059 204348448 0.005968871 −56.7047619Hypo-methylated PCa|NT DMRs chr1 204695100 204721480 0.000709087−21.75602241 Hypo-methylated PCa|NT DMRs chr1 205039042 2050390943.66E−05 −27.08333333 Hypo-methylated PCa|NT DMRs chr1 205226422205226532 6.42E−05 −38.54603175 Hypo-methylated PCa|NT DMRs chr1205312571 205313129 6.74E−10 32.21574344 Hyper-methylated PCa|NT DMRschr1 205424275 205424899 0.001210062 29.0670068 Hyper-methylated PCa|NTDMRs chr1 205449598 205453924 0.003034084 24.77380952 Hyper-methylatedPCa|NT DMRs chr1 205537857 205539322 2.00E−06 21.66488095Hyper-methylated PCa|NT DMRs chr1 206223089 206223320 0.00069655538.50649351 Hyper-methylated PCa|NT DMRs chr1 206644147 2066444921.42E−05 20.13605442 Hyper-methylated PCa|NT DMRs chr1 206679959206680526 1.23E−17 23.51253133 Hyper-methylated PCa|NT DMRs chr1207198170 207201166 0.003400006 −42.67346939 Hypo-methylated PCa|NT DMRschr1 207596832 207598015 8.35E−05 −31.01948052 Hypo-methylated PCa|NTDMRs chr1 207669481 207669836 7.86E−09 21.45142857 Hyper-methylatedPCa|NT DMRs chr1 207987203 208000382 3.44E−06 −44.11519274Hypo-methylated PCa|NT DMRs chr1 208084005 208096210 0.00609665729.11428571 Hyper-methylated PCa|NT DMRs chr1 208808282 2093156732.94E−20 −28.27251553 Hypo-methylated PCa|NT DMRs chr1 209405088209405373 1.29E−05 24.69705215 Hyper-methylated PCa|NT DMRs chr1209800707 209801480 0.002400984 −28.19047619 Hypo-methylated PCa|NT DMRschr1 209974625 209979044 0.003892841 −38.46984127 Hypo-methylated PCa|NTDMRs chr1 210036434 210062618 2.54E−09 −29.24025974 Hypo-methylatedPCa|NT DMRs chr1 211176208 211288577 7.60E−08 −22.29325397Hypo-methylated PCa|NT DMRs chr1 211652352 211652728 1.97E−0537.07142857 Hyper-methylated PCa|NT DMRs chr1 211898416 2119091820.001969641 −23.2047619 Hypo-methylated PCa|NT DMRs chr1 212415691212416118 0.001115302 −39.82619048 Hypo-methylated PCa|NT DMRs chr1212927674 212927846 0.001969641 57.67063492 Hyper-methylated PCa|NT DMRschr1 213089938 213090272 1.09E−06 36.46414566 Hyper-methylated PCa|NTDMRs chr1 213154446 213155055 9.66E−07 −44.3526455 Hypo-methylatedPCa|NT DMRs chr1 214169817 214171382 6.42E−05 −35.42539683Hypo-methylated PCa|NT DMRs chr1 214843371 214907951 1.75E−06−33.02142857 Hypo-methylated PCa|NT DMRs chr1 215810695 2162516744.48E−06 −24.88571429 Hypo-methylated PCa|NT DMRs chr1 218067939218076279 1.42E−05 −36.50510204 Hypo-methylated PCa|NT DMRs chr1218139870 218257352 2.57E−06 −24.09551821 Hypo-methylated PCa|NT DMRschr1 220132345 220136931 0.001969641 −53.36734694 Hypo-methylated PCa|NTDMRs chr1 220978575 220988536 0.001610287 27.3422619 Hyper-methylatedPCa|NT DMRs chr1 221060802 221067932 2.75E−07 22.02638353Hyper-methylated PCa|NT DMRs chr1 221067947 221291115 2.66E−08−20.94905869 Hypo-methylated PCa|NT DMRs chr1 221482362 2215099850.004095673 −29.1984127 Hypo-methylated PCa|NT DMRs chr1 223374069223382516 3.36E−06 −22.4914966 Hypo-methylated PCa|NT DMRs chr1223440701 223440923 0.001969641 −46.38095238 Hypo-methylated PCa|NT DMRschr1 223538174 223538701 1.90E−12 27.85933076 Hyper-methylated PCa|NTDMRs chr1 225655019 225656210 2.86E−05 55.2967033 Hyper-methylatedPCa|NT DMRs chr1 225865166 225865315 2.04E−05 44.13781513Hyper-methylated PCa|NT DMRs chr1 226065204 226065429 0.008482405−40.57142857 Hypo-methylated PCa|NT DMRs chr1 226310783 2263236929.84E−06 −34.60555556 Hypo-methylated PCa|NT DMRs chr1 226537535226538388 0.00068166  36.91802721 Hyper-methylated PCa|NT DMRs chr1226556933 226557092 0.005968871 37.54285714 Hyper-methylated PCa|NT DMRschr1 226593128 226593303 0.003622801 27.74206349 Hyper-methylated PCa|NTDMRs chr1 226899756 226900922 0.00064571  34.62030075 Hyper-methylatedPCa|NT DMRs chr1 228195101 228197370 6.49E−05 25.99786535Hyper-methylated PCa|NT DMRs chr1 228201122 228201256 5.84E−05−46.53174603 Hypo-methylated PCa|NT DMRs chr1 228246580 2282468820.001775064 21.90436508 Hyper-methylated PCa|NT DMRs chr1 228329098228329455 0.001969641 −30.15428571 Hypo-methylated PCa|NT DMRs chr1228344312 228345813 0.000196301 34.47896825 Hyper-methylated PCa|NT DMRschr1 228354439 228354576 0.000570576 −24.94505495 Hypo-methylated PCa|NTDMRs chr1 228401736 228402001 5.62E−06 25.7473545 Hyper-methylatedPCa|NT DMRs chr1 228633876 228634336 3.69E−11 28.0552381Hyper-methylated PCa|NT DMRs chr1 228784167 228786296 5.40E−0534.82352941 Hyper-methylated PCa|NT DMRs chr1 228857345 2288582550.001969641 −57.14965986 Hypo-methylated PCa|NT DMRs chr1 228890579228891071 5.32E−05 20.83134921 Hyper-methylated PCa|NT DMRs chr1229033902 229057326 0.005685126 32.25677656 Hyper-methylated PCa|NT DMRschr1 229203546 229203784 0.000205174 39.44642857 Hyper-methylated PCa|NTDMRs chr1 229283045 229283746 5.23E−08 32.18653061 Hyper-methylatedPCa|NT DMRs chr1 229917349 229917561 0.005968871 −35.84952381Hypo-methylated PCa|NT DMRs chr1 230193513 230193574 0.00596887136.53333333 Hyper-methylated PCa|NT DMRs chr1 230883707 2308841981.11E−05 −33.0952381 Hypo-methylated PCa|NT DMRs chr1 230976177230976487 0.000974795 −28.99702381 Hypo-methylated PCa|NT DMRs chr1231176368 231176964 5.13E−13 22.14545455 Hyper-methylated PCa|NT DMRschr1 231263394 231280946 0.000117699 −34.53982684 Hypo-methylated PCa|NTDMRs chr1 231296607 231297254 7.29E−07 22.64603175 Hyper-methylatedPCa|NT DMRs chr1 231299236 231299306 1.59E−05 22.65914787Hyper-methylated PCa|NT DMRs chr1 231347678 231347818 0.001969641−54.22619048 Hypo-methylated PCa|NT DMRs chr1 231830537 2318308150.001969641 43.38492063 Hyper-methylated PCa|NT DMRs chr1 232941139232941642 2.39E−12 32.72522523 Hyper-methylated PCa|NT DMRs chr1234261126 234261358 6.42E−05 33.12169312 Hyper-methylated PCa|NT DMRschr1 234350793 234350835 0.008482405 −33.30285714 Hypo-methylated PCa|NTDMRs chr1 234398333 234398881 0.002097193 −39.66938776 Hypo-methylatedPCa|NT DMRs chr1 234445221 234445412 0.004095673 −52.23809524Hypo-methylated PCa|NT DMRs chr1 234792339 234792735 0.00258527720.82916667 Hyper-methylated PCa|NT DMRs chr1 235105604 2351056500.008482405 −40.02857143 Hypo-methylated PCa|NT DMRs chr1 235123103235123738 0.008933897 −40.57482993 Hypo-methylated PCa|NT DMRs chr1235148032 235148290 0.005968871 60.12 Hyper-methylated PCa|NT DMRs chr1235184121 235243042 0.007959104 −20.32896825 Hypo-methylated PCa|NT DMRschr1 235255977 235256647 0.000185577 −42.72380952 Hypo-methylated PCa|NTDMRs chr1 236768539 236799430 2.89E−06 −20.47204969 Hypo-methylatedPCa|NT DMRs chr1 238011524 239092153 1.25E−36 −34.62134532Hypo-methylated PCa|NT DMRs chr1 239401388 239401479 0.000974795−34.1547619 Hypo-methylated PCa|NT DMRs chr1 240170594 2401757150.001181579 −20.35034014 Hypo-methylated PCa|NT DMRs chr1 240256554240257051 1.17E−17 23.64170772 Hyper-methylated PCa|NT DMRs chr1241541644 241575388 0.001969641 −46.97222222 Hypo-methylated PCa|NT DMRschr1 241715148 241715903 0.004553481 41.50529101 Hyper-methylated PCa|NTDMRs chr1 241729888 241730263 0.001969641 −46.82539683 Hypo-methylatedPCa|NT DMRs chr1 243074022 243255156 2.96E−08 −24.66877289Hypo-methylated PCa|NT DMRs chr1 244243867 244244145 0.001480644−20.02857143 Hypo-methylated PCa|NT DMRs chr1 244387932 2443884730.008482405 47.8152381 Hyper-methylated PCa|NT DMRs chr1 245217861245218040 0.005968871 49.1 Hyper-methylated PCa|NT DMRs chr1 245736547245736596 0.005968871 −32.41142857 Hypo-methylated PCa|NT DMRs chr1245772696 245773403 1.97E−05 −55.05714286 Hypo-methylated PCa|NT DMRschr1 246866819 246867124 0.008234951 32.37142857 Hyper-methylated PCa|NTDMRs chr1 246939151 246939711 8.35E−08 −50.01492063 Hypo-methylatedPCa|NT DMRs chr1 246945661 246945871 0.005968871 43.71428571Hyper-methylated PCa|NT DMRs chr1 247535548 247535896 0.001969641−44.76190476 Hypo-methylated PCa|NT DMRs chr1 247538743 2475738001.87E−06 −25.68571429 Hypo-methylated PCa|NT DMRs chr1 247590008247614728 2.39E−08 −34.12802198 Hypo-methylated PCa|NT DMRs chr1248143991 248481926 3.09E−10 −30.7972973 Hypo-methylated PCa|NT DMRschr1 248685329 248685733 7.19E−05 −28.08531746 Hypo-methylated PCa|NTDMRs chr1 249090768 249097012 0.001344447 −26.875 Hypo-methylated PCa|NTDMRs chr1 249097719 249099771 0.000456684 30.74206349 Hyper-methylatedPCa|NT DMRs chr2 11910 14238 0.008511532 −32.38461538 Hypo-methylatedPCa|NT DMRs chr2 45448 46433 3.18E−25 20.43745645 Hyper-methylatedPCa|NT DMRs chr2 439970 440149 0.001969641 −28.52380952 Hypo-methylatedPCa|NT DMRs chr2 496069 497417 1.02E−09 −26.19708995 Hypo-methylatedPCa|NT DMRs chr2 636544 637016 7.46E−11 28.13809524 Hyper-methylatedPCa|NT DMRs chr2 793307 795479 0.000840726 −23.87037037 Hypo-methylatedPCa|NT DMRs chr2 875812 876008 9.97E−07 −21.22285714 Hypo-methylatedPCa|NT DMRs chr2 1591015 1593315 8.23E−05 25.76266667 Hyper-methylatedPCa|NT DMRs chr2 1609014 1613663 0.000258503 29.47985348Hyper-methylated PCa|NT DMRs chr2 1628029 1629157 0.002750151−33.37174603 Hypo-methylated PCa|NT DMRs chr2 1679317 1679866 6.42E−05−56.53968254 Hypo-methylated PCa|NT DMRs chr2 1771043 17721990.001152293 24.00571429 Hyper-methylated PCa|NT DMRs chr2 17971851797682 0.00057866  −21.25047619 Hypo-methylated PCa|NT DMRs chr21839428 1839689 0.005968871 −54.06190476 Hypo-methylated PCa|NT DMRschr2 1869405 1873216 0.000754912 −24.50571429 Hypo-methylated PCa|NTDMRs chr2 1880304 1893255 6.21E−07 −22.84901961 Hypo-methylated PCa|NTDMRs chr2 1896195 1914113 5.13E−15 −25.7469246 Hypo-methylated PCa|NTDMRs chr2 1999403 1999862 0.000205174 28.85714286 Hyper-methylatedPCa|NT DMRs chr2 2007603 2018579 0.001969641 −27.55714286Hypo-methylated PCa|NT DMRs chr2 2189948 2190029 1.42E−05 −32.26360544Hypo-methylated PCa|NT DMRs chr2 2295453 2404659 9.60E−07 −25.5168254Hypo-methylated PCa|NT DMRs chr2 2414861 2542083 3.32E−15 −29.53874092Hypo-methylated PCa|NT DMRs chr2 2581317 2604372 4.85E−13 −31.88950216Hypo-methylated PCa|NT DMRs chr2 2617176 2645948 5.78E−06 −22.20675526Hypo-methylated PCa|NT DMRs chr2 2666095 2667656 0.000384643 −32.58125Hypo-methylated PCa|NT DMRs chr2 2673279 2697612 2.88E−09 −25.39968254Hypo-methylated PCa|NT DMRs chr2 2712829 2725315 9.78E−12 −32.51303258Hypo-methylated PCa|NT DMRs chr2 2881302 2893716 2.86E−05 −32.07216117Hypo-methylated PCa|NT DMRs chr2 3352486 3367076 1.57E−07 −40.09269841Hypo-methylated PCa|NT DMRs chr2 3628198 3633408 1.03E−05 −47.90595238Hypo-methylated PCa|NT DMRs chr2 3827278 3827480 0.00064571 −31.93877551 Hypo-methylated PCa|NT DMRs chr2 4976712 49768710.004095673 −51.85714286 Hypo-methylated PCa|NT DMRs chr2 55828075583012 0.007959104 −45.16326531 Hypo-methylated PCa|NT DMRs chr26072686 6072920 0.00064571  −58.97959184 Hypo-methylated PCa|NT DMRschr2 6121557 6121728 0.007959104 26.30544218 Hyper-methylated PCa|NTDMRs chr2 7571040 7571792 5.50E−18 27.36613011 Hyper-methylated PCa|NTDMRs chr2 8275330 8275400 0.001969641 20.47619048 Hyper-methylatedPCa|NT DMRs chr2 8595402 8597487 4.59E−07 40.8989899 Hyper-methylatedPCa|NT DMRs chr2 8613061 8617825 0.001969641 51.67857143Hyper-methylated PCa|NT DMRs chr2 8767329 8767651 0.000651745−39.86904762 Hypo-methylated PCa|NT DMRs chr2 8804887 88052230.000228994 31.70684524 Hyper-methylated PCa|NT DMRs chr2 92299899236237 4.36E−06 34.61830357 Hyper-methylated PCa|NT DMRs chr2 99378369938039 0.001969641 −45.47936508 Hypo-methylated PCa|NT DMRs chr29956025 9964206 0.003448944 23.70884354 Hyper-methylated PCa|NT DMRschr2 10168865 10169784 0.005938065 24.05714286 Hyper-methylated PCa|NTDMRs chr2 10182542 10183283 1.03E−06 25.11885714 Hyper-methylated PCa|NTDMRs chr2 10196817 10196899 0.001969641 −52.61111111 Hypo-methylatedPCa|NT DMRs chr2 10200402 10200648 0.007628253 −34.83673469Hypo-methylated PCa|NT DMRs chr2 10220817 10220994 5.01E−06 21.55166667Hyper-methylated PCa|NT DMRs chr2 10367948 10369419 0.001291665−41.91168831 Hypo-methylated PCa|NT DMRs chr2 10529276 105366990.001899053 20.09467787 Hyper-methylated PCa|NT DMRs chr2 1054104910546988 2.33E−07 24.88275418 Hyper-methylated PCa|NT DMRs chr2 1055000910550372 0.000205174 44.45654762 Hyper-methylated PCa|NT DMRs chr210570707 10573271 1.34E−07 33.54518272 Hyper-methylated PCa|NT DMRs chr211054446 11054665 0.005968871 22.32857143 Hyper-methylated PCa|NT DMRschr2 11058934 11059334 0.003272154 −25.09821429 Hypo-methylated PCa|NTDMRs chr2 11087220 11087315 0.001969641 34.0968254 Hyper-methylatedPCa|NT DMRs chr2 11117281 11117480 0.000117699 39.35064935Hyper-methylated PCa|NT DMRs chr2 11269676 11269781 0.00064571 44.9537415 Hyper-methylated PCa|NT DMRs chr2 11273541 112948390.000694428 20.65901361 Hyper-methylated PCa|NT DMRs chr2 1153904511539312 0.003448944 −31.57959184 Hypo-methylated PCa|NT DMRs chr211794703 11797035 1.76E−06 −47.14285714 Hypo-methylated PCa|NT DMRs chr211816545 11816928 0.00064571  −31.00884354 Hypo-methylated PCa|NT DMRschr2 11817063 11818013 0.000144451 26.43465608 Hyper-methylated PCa|NTDMRs chr2 11822852 11823131 0.002767976 −28.02597403 Hypo-methylatedPCa|NT DMRs chr2 11990386 11990468 0.000377317 −22.75892857Hypo-methylated PCa|NT DMRs chr2 12083451 12124397 0.005968871−20.42857143 Hypo-methylated PCa|NT DMRs chr2 12858923 12859080 1.68E−0632.37310924 Hyper-methylated PCa|NT DMRs chr2 15174632 151819490.005513661 −26.76488095 Hypo-methylated PCa|NT DMRs chr2 1590918015910005 0.001115302 26.37797619 Hyper-methylated PCa|NT DMRs chr215925398 15928759 5.06E−06 −26.0070028 Hypo-methylated PCa|NT DMRs chr216082898 16089407 0.002668449 20.87843137 Hyper-methylated PCa|NT DMRschr2 16386194 16448084 0.000355892 −26.4 Hypo-methylated PCa|NT DMRschr2 16744057 16780770 0.000205174 −21.00595238 Hypo-methylated PCa|NTDMRs chr2 20068429 20068953 2.52E−13 38.86446886 Hyper-methylated PCa|NTDMRs chr2 20385350 20386297 0.000974795 27.31785714 Hyper-methylatedPCa|NT DMRs chr2 20396474 20396637 1.97E−05 −52.62142857 Hypo-methylatedPCa|NT DMRs chr2 20412821 20413626 0.004095673 −55.71269841Hypo-methylated PCa|NT DMRs chr2 20644948 20646182 0.00277341721.29444444 Hyper-methylated PCa|NT DMRs chr2 20647265 20648260 8.59E−07−27.25666667 Hypo-methylated PCa|NT DMRs chr2 21925827 22114299 1.52E−07−32.10612245 Hypo-methylated PCa|NT DMRs chr2 22307033 23000777 5.18E−21−31.68116883 Hypo-methylated PCa|NT DMRs chr2 23178425 232328960.002373155 −33.46825397 Hypo-methylated PCa|NT DMRs chr2 2388154123886385 0.000101817 22.41269841 Hyper-methylated PCa|NT DMRs chr223936461 24015758 0.009382828 33.77460317 Hyper-methylated PCa|NT DMRschr2 24272701 24273290 1.92E−12 22.83521595 Hyper-methylated PCa|NT DMRschr2 24397760 24398064 4.01E−08 26.50746032 Hyper-methylated PCa|NT DMRschr2 25023163 25038618 0.001394173 −34.61530612 Hypo-methylated PCa|NTDMRs chr2 25097021 25109925 4.63E−05 24.87563025 Hyper-methylated PCa|NTDMRs chr2 25149334 25151402 2.81E−06 41.5007619 Hyper-methylated PCa|NTDMRs chr2 25209069 25220341 0.001969641 −29.17857143 Hypo-methylatedPCa|NT DMRs chr2 25425302 25427514 6.86E−18 39.06543779 Hyper-methylatedPCa|NT DMRs chr2 25799754 25800026 0.00179283  −39.09821429Hypo-methylated PCa|NT DMRs chr2 25805082 25805160 0.00596887132.81428571 Hyper-methylated PCa|NT DMRs chr2 26045138 260451770.005968871 25.80952381 Hyper-methylated PCa|NT DMRs chr2 2613949826139524 0.008482405 57.54285714 Hyper-methylated PCa|NT DMRs chr226204700 26204995 5.06E−06 29.79551821 Hyper-methylated PCa|NT DMRs chr226394194 26395683 0.000220386 25.21137026 Hyper-methylated PCa|NT DMRschr2 26521360 26523216 2.01E−07 45.51071429 Hyper-methylated PCa|NT DMRschr2 26624616 26625140 7.76E−14 34.73571429 Hyper-methylated PCa|NT DMRschr2 26700315 26700393 0.004037929 38.83673469 Hyper-methylated PCa|NTDMRs chr2 26872310 26872729 0.000339627 −44.02777778 Hypo-methylatedPCa|NT DMRs chr2 27045085 27068314 0.00023371  −20.89914966Hypo-methylated PCa|NT DMRs chr2 27072408 27072835 3.91E−13 21.25736961Hyper-methylated PCa|NT DMRs chr2 27194059 27194443 0.00064571 24.96258503 Hyper-methylated PCa|NT DMRs chr2 27529119 27530773 2.26E−2736.86595945 Hyper-methylated PCa|NT DMRs chr2 27599189 276018560.007177823 −24.13613445 Hypo-methylated PCa|NT DMRs chr2 2766512927665651 2.05E−17 −33.5462963 Hypo-methylated PCa|NT DMRs chr2 2795358927960870 1.03E−08 36.57380952 Hyper-methylated PCa|NT DMRs chr2 2863306028633406 0.000354065 51.36507937 Hyper-methylated PCa|NT DMRs chr228976750 28976898 0.004947537 −25.11111111 Hypo-methylated PCa|NT DMRschr2 29033353 29034134 3.51E−13 26.9191342 Hyper-methylated PCa|NT DMRschr2 29338031 29338356 8.16E−17 23.01923077 Hyper-methylated PCa|NT DMRschr2 30455541 30455705 1.64E−06 20.06890756 Hyper-methylated PCa|NT DMRschr2 30559925 30561092 0.002767976 23.35670996 Hyper-methylated PCa|NTDMRs chr2 30885534 30885833 0.000205174 −52.87559524 Hypo-methylatedPCa|NT DMRs chr2 30998710 30999051 0.001344447 49.89880952Hyper-methylated PCa|NT DMRs chr2 31942306 31962425 0.005968871−20.1752381 Hypo-methylated PCa|NT DMRs chr2 33532846 335330350.005968871 −53.06666667 Hypo-methylated PCa|NT DMRs chr2 3604172236528260 7.69E−11 −25.96152381 Hypo-methylated PCa|NT DMRs chr2 3830086238301774 5.29E−23 30.02061224 Hyper-methylated PCa|NT DMRs chr2 3882718038827869 0.005968871 −26.81216931 Hypo-methylated PCa|NT DMRs chr239186938 39187433 1.15E−05 21.67746032 Hyper-methylated PCa|NT DMRs chr239472228 39472654 5.84E−05 44.60714286 Hyper-methylated PCa|NT DMRs chr239892612 39892964 9.62E−06 26.81534392 Hyper-methylated PCa|NT DMRs chr240225200 40270225 0.000377317 −25.82083333 Hypo-methylated PCa|NT DMRschr2 40498961 40558601 4.84E−06 −22.95029762 Hypo-methylated PCa|NT DMRschr2 42106019 42106107 0.008482405 46.54285714 Hyper-methylated PCa|NTDMRs chr2 43132698 43133093 0.000366497 30.02380952 Hyper-methylatedPCa|NT DMRs chr2 43153331 43153629 0.001969641 −57.66031746Hypo-methylated PCa|NT DMRs chr2 43161979 43165586 0.00208519722.03174603 Hyper-methylated PCa|NT DMRs chr2 43228043 432336250.008581782 24.20982143 Hyper-methylated PCa|NT DMRs chr2 4328616043294887 0.000481535 28.88095238 Hyper-methylated PCa|NT DMRs chr243396962 43405569 2.40E−07 46.00421245 Hyper-methylated PCa|NT DMRs chr244933808 45014780 1.77E−05 29.78761905 Hyper-methylated PCa|NT DMRs chr245149217 45155504 8.34E−07 25.54679803 Hyper-methylated PCa|NT DMRs chr245163020 45165772 3.88E−10 28.48441558 Hyper-methylated PCa|NT DMRs chr245396723 45398172 3.52E−12 31.25136054 Hyper-methylated PCa|NT DMRs chr245485264 45485490 0.00046742  36.19480519 Hyper-methylated PCa|NT DMRschr2 45501627 45501894 0.001969641 −48.57857143 Hypo-methylated PCa|NTDMRs chr2 46523506 46523905 0.003450017 20.29828571 Hyper-methylatedPCa|NT DMRs chr2 46558860 46562940 0.001391421 −24.51082251Hypo-methylated PCa|NT DMRs chr2 46770499 46770976 2.42E−07 29.98302277Hyper-methylated PCa|NT DMRs chr2 47206494 47210755 1.11E−05 54.75324675Hyper-methylated PCa|NT DMRs chr2 48209009 48316147 4.77E−05−22.17482993 Hypo-methylated PCa|NT DMRs chr2 48994644 49054084 1.77E−05−32.62142857 Hypo-methylated PCa|NT DMRs chr2 49143214 49160870 1.42E−05−31.41326531 Hypo-methylated PCa|NT DMRs chr2 49222362 493456040.001969641 −36.1031746 Hypo-methylated PCa|NT DMRs chr2 4975177249800742 0.000392715 −26.12380952 Hypo-methylated PCa|NT DMRs chr252799450 53537533 1.96E−30 −28.5737646 Hypo-methylated PCa|NT DMRs chr254900534 54901150 4.90E−06 42.02678571 Hyper-methylated PCa|NT DMRs chr255349410 55381244 0.002713936 33.16883117 Hyper-methylated PCa|NT DMRschr2 55960177 56022539 1.52E−07 −24.69897959 Hypo-methylated PCa|NT DMRschr2 56238691 56410072 0.00064571  −33.15102041 Hypo-methylated PCa|NTDMRs chr2 56420144 58077786 2.52E−30 −32.34753247 Hypo-methylated PCa|NTDMRs chr2 58478744 58654887 2.42E−06 −30.5802381 Hypo-methylated PCa|NTDMRs chr2 58751739 59288266 3.34E−15 −37.03481481 Hypo-methylated PCa|NTDMRs chr2 59294363 59580792 3.90E−09 −36.65996473 Hypo-methylated PCa|NTDMRs chr2 60666901 60667013 0.001115302 32.71845238 Hyper-methylatedPCa|NT DMRs chr2 60674391 60687915 4.45E−08 −29.43079365 Hypo-methylatedPCa|NT DMRs chr2 62520450 62521440 0.001969641 −32.73190476Hypo-methylated PCa|NT DMRs chr2 64291259 64291471 0.008482405−55.42857143 Hypo-methylated PCa|NT DMRs chr2 64682113 646822940.003544378 −31.91428571 Hypo-methylated PCa|NT DMRs chr2 6483412664834341 0.001969641 42.64285714 Hyper-methylated PCa|NT DMRs chr264836278 64836819 1.10E−14 23.87319902 Hyper-methylated PCa|NT DMRs chr264863610 64863692 6.42E−05 51.58730159 Hyper-methylated PCa|NT DMRs chr265173463 65173694 0.005968871 58.09047619 Hyper-methylated PCa|NT DMRschr2 65793940 65794008 0.001969641 38.5 Hyper-methylated PCa|NT DMRschr2 65958699 65958944 0.005968871 −24.0952381 Hypo-methylated PCa|NTDMRs chr2 66096573 66309102 4.59E−06 −20.42335601 Hypo-methylated PCa|NTDMRs chr2 67788644 67971406 0.003448944 −47.26190476 Hypo-methylatedPCa|NT DMRs chr2 69001774 69002219 6.63E−10 43.81734694 Hyper-methylatedPCa|NT DMRs chr2 69524089 69533971 3.27E−06 20.71333333 Hyper-methylatedPCa|NT DMRs chr2 70202705 70205900 0.000396159 34.85 Hyper-methylatedPCa|NT DMRs chr2 70905810 70905975 0.001969641 −28.97959184Hypo-methylated PCa|NT DMRs chr2 71192319 71192453 0.00011653325.08225108 Hyper-methylated PCa|NT DMRs chr2 71271947 71272816 7.19E−05−33.53571429 Hypo-methylated PCa|NT DMRs chr2 71692287 716933280.001037738 28.00285714 Hyper-methylated PCa|NT DMRs chr2 7183219171832252 0.005968871 41.6 Hyper-methylated PCa|NT DMRs chr2 7192735971928137 0.006738891 −25.66598639 Hypo-methylated PCa|NT DMRs chr271944105 71944338 0.000205174 −43.95833333 Hypo-methylated PCa|NT DMRschr2 71974171 71974392 0.000481535 −24.68253968 Hypo-methylated PCa|NTDMRs chr2 72012720 72013043 0.000215808 32.92328042 Hyper-methylatedPCa|NT DMRs chr2 72369534 72371794 1.83E−11 32.8714966 Hyper-methylatedPCa|NT DMRs chr2 73512124 73512214 0.003892841 29.73015873Hyper-methylated PCa|NT DMRs chr2 73551380 73605217 0.003105416−26.403663 Hypo-methylated PCa|NT DMRs chr2 73931532 739318290.004005318 49.97619048 Hyper-methylated PCa|NT DMRs chr2 7413824474153214 0.00022692  −22.96825397 Hypo-methylated PCa|NT DMRs chr274252650 74252691 0.008482405 44.09142857 Hyper-methylated PCa|NT DMRschr2 74412615 74412808 0.000205174 43.21428571 Hyper-methylated PCa|NTDMRs chr2 74641954 74643332 4.02E−10 31.96451914 Hyper-methylated PCa|NTDMRs chr2 74667768 74668636 0.002152552 −21.59353741 Hypo-methylatedPCa|NT DMRs chr2 74779511 74779629 0.001969641 44.53469388Hyper-methylated PCa|NT DMRs chr2 75292212 75292273 0.00196964145.28968254 Hyper-methylated PCa|NT DMRs chr2 76077436 76366398 7.54E−12−30.14414414 Hypo-methylated PCa|NT DMRs chr2 76975571 77061259 1.69E−06−52.71428571 Hypo-methylated PCa|NT DMRs chr2 77925980 77961243 3.51E−05−27.65054945 Hypo-methylated PCa|NT DMRs chr2 79006310 79077222 8.75E−09−27.07777778 Hypo-methylated PCa|NT DMRs chr2 79102826 79187496 6.42E−05−25.01798942 Hypo-methylated PCa|NT DMRs chr2 79492296 79684185 6.55E−13−33.63675214 Hypo-methylated PCa|NT DMRs chr2 79779504 79897577 7.12E−08−31.03152709 Hypo-methylated PCa|NT DMRs chr2 80334595 80494816 7.80E−07−34.53257143 Hypo-methylated PCa|NT DMRs chr2 80557949 80773063 2.15E−08−38.6127619 Hypo-methylated PCa|NT DMRs chr2 81098971 811280100.000205174 −40.40178571 Hypo-methylated PCa|NT DMRs chr2 8410283384522159 2.54E−16 −33.18380952 Hypo-methylated PCa|NT DMRs chr2 8509275685098904 0.00641359  −37.42857143 Hypo-methylated PCa|NT DMRs chr285106954 85107452 6.94E−06 40.72952381 Hyper-methylated PCa|NT DMRs chr285361978 85362295 3.44E−06 38.5625 Hyper-methylated PCa|NT DMRs chr285640740 85644803 1.24E−06 27.3577573 Hyper-methylated PCa|NT DMRs chr285888390 85888724 0.001969641 22.13809524 Hyper-methylated PCa|NT DMRschr2 85938636 85949493 0.000200126 35.42155388 Hyper-methylated PCa|NTDMRs chr2 85975464 85980817 6.13E−05 30.80912698 Hyper-methylated PCa|NTDMRs chr2 86001690 86017953 0.003410476 24.61724138 Hyper-methylatedPCa|NT DMRs chr2 86245145 86248352 0.000908257 −35.01318681Hypo-methylated PCa|NT DMRs chr2 87581832 87743769 1.28E−07 −37.84246032Hypo-methylated PCa|NT DMRs chr2 88248026 88301765 0.001471804−26.25793651 Hypo-methylated PCa|NT DMRs chr2 88591069 88649189 1.73E−08−40.49047619 Hypo-methylated PCa|NT DMRs chr2 88756044 88791818 2.79E−08−33.61904762 Hypo-methylated PCa|NT DMRs chr2 90469037 90485802 1.22E−06−28.98571429 Hypo-methylated PCa|NT DMRs chr2 91678864 916980730.000435385 −33.4003663 Hypo-methylated PCa|NT DMRs chr2 9170642691755271 0.005968871 −33.14285714 Hypo-methylated PCa|NT DMRs chr291940484 91957149 0.003032307 −29.10578231 Hypo-methylated PCa|NT DMRschr2 95523816 95524163 8.42E−05 28.52380952 Hyper-methylated PCa|NT DMRschr2 95539703 95539830 0.00179283  −27.50714286 Hypo-methylated PCa|NTDMRs chr2 95692274 95693115 7.43E−07 23.28154762 Hyper-methylated PCa|NTDMRs chr2 95884907 95899095 0.000205174 −26.12142857 Hypo-methylatedPCa|NT DMRs chr2 96012660 96013247 0.003095938 20.60345238Hyper-methylated PCa|NT DMRs chr2 96829878 96830574 0.00104283323.28571429 Hyper-methylated PCa|NT DMRs chr2 96990968 96991937 1.95E−1123.34639456 Hyper-methylated PCa|NT DMRs chr2 97151767 971522490.000205174 39.15357143 Hyper-methylated PCa|NT DMRs chr2 9717435097191875 0.000600104 −26.98129252 Hypo-methylated PCa|NT DMRs chr297203371 97203683 2.58E−05 26.6970696 Hyper-methylated PCa|NT DMRs chr297504837 97505294 0.001060348 42.37662338 Hyper-methylated PCa|NT DMRschr2 97532102 97532830 0.000102305 32.36825397 Hyper-methylated PCa|NTDMRs chr2 97533635 97534300 1.47E−05 21.70907029 Hyper-methylated PCa|NTDMRs chr2 98329337 98330350 1.24E−07 29.11309524 Hyper-methylated PCa|NTDMRs chr2 98896930 98897302 0.00179283  27.63988095 Hyper-methylatedPCa|NT DMRs chr2 99796276 99796456 0.001969641 −43.72619048Hypo-methylated PCa|NT DMRs chr2 100186071 100189473 0.00064571 −24.11020408 Hypo-methylated PCa|NT DMRs chr2 100722012 1007637570.008083098 −23.62063492 Hypo-methylated PCa|NT DMRs chr2 100851655100851922 0.000205174 53.55297619 Hyper-methylated PCa|NT DMRs chr2100956434 100998861 0.001969641 −25.95952381 Hypo-methylated PCa|NT DMRschr2 101619642 101619885 0.007959104 −37.81632653 Hypo-methylated PCa|NTDMRs chr2 101926330 101929961 0.001969641 37.37301587 Hyper-methylatedPCa|NT DMRs chr2 103464975 103465123 5.78E−05 29.03571429Hyper-methylated PCa|NT DMRs chr2 104973286 105235377 5.04E−17−38.82587065 Hypo-methylated PCa|NT DMRs chr2 105853623 1058537816.42E−05 50.63492063 Hyper-methylated PCa|NT DMRs chr2 105979730105979901 0.005968871 46.4 Hyper-methylated PCa|NT DMRs chr2 106014832106015180 3.04E−08 26.74202899 Hyper-methylated PCa|NT DMRs chr2106548681 106571947 0.00068166  −21.37142857 Hypo-methylated PCa|NT DMRschr2 107484769 107485028 0.003622801 −31.81428571 Hypo-methylated PCa|NTDMRs chr2 108888469 108889211 3.32E−06 −57.38492063 Hypo-methylatedPCa|NT DMRs chr2 108990108 108990417 0.00023371  −48.78571429Hypo-methylated PCa|NT DMRs chr2 109196276 109196645 0.00020517422.85714286 Hyper-methylated PCa|NT DMRs chr2 109840995 1098552620.001429556 33.6038961 Hyper-methylated PCa|NT DMRs chr2 109907927109908003 0.000215808 −24.03174603 Hypo-methylated PCa|NT DMRs chr2110372895 110373059 0.000377317 25.03571429 Hyper-methylated PCa|NT DMRschr2 112123978 112124095 2.73E−06 20.11071429 Hyper-methylated PCa|NTDMRs chr2 112897975 112898369 2.31E−07 33.76309524 Hyper-methylatedPCa|NT DMRs chr2 112913017 112915980 0.001041221 30.76526611Hyper-methylated PCa|NT DMRs chr2 113930805 113933877 0.00529576130.47012987 Hyper-methylated PCa|NT DMRs chr2 113955773 1139559730.000205174 −29.79166667 Hypo-methylated PCa|NT DMRs chr2 114048902114063733 0.002580892 38.78571429 Hyper-methylated PCa|NT DMRs chr2115294076 115407087 7.51E−07 −41.8015873 Hypo-methylated PCa|NT DMRschr2 115542670 115918201 1.87E−16 −31.58872692 Hypo-methylated PCa|NTDMRs chr2 115935859 117309836 3.44E−31 −32.21763393 Hypo-methylatedPCa|NT DMRs chr2 117602049 117784436 6.42E−05 −35.13915344Hypo-methylated PCa|NT DMRs chr2 119599195 119599642 0.00070675122.21577381 Hyper-methylated PCa|NT DMRs chr2 119703150 1197518592.30E−06 −32.40136054 Hypo-methylated PCa|NT DMRs chr2 119809598119902570 7.85E−08 −24.8805291 Hypo-methylated PCa|NT DMRs chr2119982015 119985068 0.009050681 21.67238095 Hyper-methylated PCa|NT DMRschr2 120418595 120436086 0.003622801 −26.52142857 Hypo-methylated PCa|NTDMRs chr2 121156865 121157082 0.000118733 −34.4978836 Hypo-methylatedPCa|NT DMRs chr2 121158454 121162391 0.003892841 22.23809524Hyper-methylated PCa|NT DMRs chr2 121411913 121412564 1.48E−0524.70457875 Hyper-methylated PCa|NT DMRs chr2 121499560 1214997830.002585277 22.37738095 Hyper-methylated PCa|NT DMRs chr2 121624808121625839 1.70E−07 20.43205575 Hyper-methylated PCa|NT DMRs chr2121691704 121698626 0.001430886 −29.98214286 Hypo-methylated PCa|NT DMRschr2 121748671 121750909 0.006589535 22.46952381 Hyper-methylated PCa|NTDMRs chr2 121763736 121763822 0.000205174 −58.57738095 Hypo-methylatedPCa|NT DMRs chr2 121776280 121778871 0.005438982 21.17380952Hyper-methylated PCa|NT DMRs chr2 121820414 121820577 0.00064571 −40.42857143 Hypo-methylated PCa|NT DMRs chr2 122042236 1220424842.69E−09 35.80842491 Hyper-methylated PCa|NT DMRs chr2 122522793122522900 0.00641359  25.58888889 Hyper-methylated PCa|NT DMRs chr2122532880 122545681 0.000205174 −24.7797619 Hypo-methylated PCa|NT DMRschr2 122660705 122720549 0.003847481 −29.21804511 Hypo-methylated PCa|NTDMRs chr2 122809721 122809788 1.97E−05 −43.13809524 Hypo-methylatedPCa|NT DMRs chr2 123989564 124002963 0.001969641 −26.78095238Hypo-methylated PCa|NT DMRs chr2 124669211 124782299 8.93E−0628.88971429 Hyper-methylated PCa|NT DMRs chr2 127536795 1276434956.87E−21 −34.39964986 Hypo-methylated PCa|NT DMRs chr2 127643858127643939 0.001181579 21.2755102 Hyper-methylated PCa|NT DMRs chr2127644612 127695655 6.21E−05 −38.25612245 Hypo-methylated PCa|NT DMRschr2 127734072 127754753 5.33E−05 −29.4021978 Hypo-methylated PCa|NTDMRs chr2 127770008 127770465 0.005968871 −38.1952381 Hypo-methylatedPCa|NT DMRs chr2 127836137 127839768 0.002843063 32.9985119Hyper-methylated PCa|NT DMRs chr2 127844776 127845178 0.00064571 35.13605442 Hyper-methylated PCa|NT DMRs chr2 127933204 1279349210.000532147 −20.97857143 Hypo-methylated PCa|NT DMRs chr2 127950803127955560 0.00998923  −21.05625 Hypo-methylated PCa|NT DMRs chr2128340902 128341171 0.007959104 −22.63741497 Hypo-methylated PCa|NT DMRschr2 128432170 128432409 0.001924648 27.57922078 Hyper-methylated PCa|NTDMRs chr2 129037458 129037906 0.000481535 56.47566138 Hyper-methylatedPCa|NT DMRs chr2 129492225 129492818 0.000205174 49.71428571Hyper-methylated PCa|NT DMRs chr2 130952660 130952745 0.005968871−51.96190476 Hypo-methylated PCa|NT DMRs chr2 131594992 1315991460.001860358 20.20984127 Hyper-methylated PCa|NT DMRs chr2 131723528131724245 0.003448944 20.6122449 Hyper-methylated PCa|NT DMRs chr2131875716 131884270 0.005968871 −39.05714286 Hypo-methylated PCa|NT DMRschr2 132056960 132109945 0.005513661 21.16296296 Hyper-methylated PCa|NTDMRs chr2 132236936 132237183 0.00064571  −52.07619048 Hypo-methylatedPCa|NT DMRs chr2 132559025 132559272 0.006410012 −21.43040293Hypo-methylated PCa|NT DMRs chr2 132589570 132589637 0.00209719325.56802721 Hyper-methylated PCa|NT DMRs chr2 132795209 1327952580.008482405 42.68571429 Hyper-methylated PCa|NT DMRs chr2 133015816133025559 2.88E−06 −21.17628766 Hypo-methylated PCa|NT DMRs chr2133025978 133029690 0.000260619 −23.1389234 Hypo-methylated PCa|NT DMRschr2 133428721 133456173 1.31E−05 29.52748918 Hyper-methylated PCa|NTDMRs chr2 134657449 134776379 0.000117039 −28.76666667 Hypo-methylatedPCa|NT DMRs chr2 134928727 135025810 0.008581782 25.45436508Hyper-methylated PCa|NT DMRs chr2 137164351 137172836 0.000822388−24.29393939 Hypo-methylated PCa|NT DMRs chr2 137244040 1373430600.005302622 −22.42232143 Hypo-methylated PCa|NT DMRs chr2 137354387137411341 0.001969641 −37.07142857 Hypo-methylated PCa|NT DMRs chr2137543069 138417393 5.62E−15 −30.99515599 Hypo-methylated PCa|NT DMRschr2 140607151 142022624 3.97E−25 −26.06710398 Hypo-methylated PCa|NTDMRs chr2 145281942 145281994 1.76E−06 33.45833333 Hyper-methylatedPCa|NT DMRs chr2 146597676 147298861 8.85E−16 −27.32891156Hypo-methylated PCa|NT DMRs chr2 149854919 149859916 0.001111028−20.55555556 Hypo-methylated PCa|NT DMRs chr2 150176902 1501772781.56E−08 26.61904762 Hyper-methylated PCa|NT DMRs chr2 151281772151282012 0.005968871 29.86190476 Hyper-methylated PCa|NT DMRs chr2153797945 154113653 4.78E−07 −26.7689441 Hypo-methylated PCa|NT DMRschr2 154634412 154675055 0.000840726 −20.85873016 Hypo-methylated PCa|NTDMRs chr2 155554932 155556069 9.47E−07 31.3859127 Hyper-methylatedPCa|NT DMRs chr2 156456945 156457000 0.000205174 −37.96071429Hypo-methylated PCa|NT DMRs chr2 157179350 157186447 1.85E−3142.20275229 Hyper-methylated PCa|NT DMRs chr2 158607880 1586079920.005968871 −39.39619048 Hypo-methylated PCa|NT DMRs chr2 162095496162101550 4.97E−08 20.83281573 Hyper-methylated PCa|NT DMRs chr2162115207 162138207 0.001583613 −23.71731602 Hypo-methylated PCa|NT DMRschr2 162301847 162311737 4.30E−05 −25.19413919 Hypo-methylated PCa|NTDMRs chr2 162482247 162482398 0.001969641 39.5952381 Hyper-methylatedPCa|NT DMRs chr2 165811678 165851629 0.001089765 −25.2359944Hypo-methylated PCa|NT DMRs chr2 167088223 167225136 1.97E−05−32.36666667 Hypo-methylated PCa|NT DMRs chr2 167271040 1674067250.003892841 −33.3047619 Hypo-methylated PCa|NT DMRs chr2 167594864167622982 0.002534928 −33.74047619 Hypo-methylated PCa|NT DMRs chr2169585372 169585445 0.005968871 −29.2 Hypo-methylated PCa|NT DMRs chr2170563283 170573652 0.000266788 −38.15638095 Hypo-methylated PCa|NT DMRschr2 172972302 172974226 1.03E−09 40.29130435 Hyper-methylated PCa|NTDMRs chr2 173330355 173330425 0.000117507 −54.07792208 Hypo-methylatedPCa|NT DMRs chr2 174313921 174314045 0.00576331  −20.28869048Hypo-methylated PCa|NT DMRs chr2 174397678 174448404 0.000339757−31.91125541 Hypo-methylated PCa|NT DMRs chr2 174877326 1748777626.73E−08 25.17354497 Hyper-methylated PCa|NT DMRs chr2 175190675175199882 2.15E−30 27.129634 Hyper-methylated PCa|NT DMRs chr2 175437120175445027 0.004095673 26.68650794 Hyper-methylated PCa|NT DMRs chr2177001780 177004583 4.70E−07 38.03968254 Hyper-methylated PCa|NT DMRschr2 177053478 177054838 1.53E−20 26.16380952 Hyper-methylated PCa|NTDMRs chr2 179397807 179399188 0.001969641 46.63605442 Hyper-methylatedPCa|NT DMRs chr2 180184481 180184526 0.005968871 −25.92666667Hypo-methylated PCa|NT DMRs chr2 180726644 180726742 0.00011769944.8025974 Hyper-methylated PCa|NT DMRs chr2 183579384 1835795820.00064571  −48.63227513 Hypo-methylated PCa|NT DMRs chr2 184594781184594866 0.001969641 −43.47619048 Hypo-methylated PCa|NT DMRs chr2184957584 185440919 7.58E−13 −31.97978836 Hypo-methylated PCa|NT DMRschr2 185463763 185602040 2.42E−05 −34.81278195 Hypo-methylated PCa|NTDMRs chr2 185708150 185918405 0.001969641 −23.43333333 Hypo-methylatedPCa|NT DMRs chr2 186123428 186230566 0.00017871  −20.22095238Hypo-methylated PCa|NT DMRs chr2 187735461 187799347 0.004095673−28.1984127 Hypo-methylated PCa|NT DMRs chr2 187837330 1878679583.65E−05 −24.39724311 Hypo-methylated PCa|NT DMRs chr2 191042211191045733 1.80E−22 37.05605787 Hyper-methylated PCa|NT DMRs chr2192130371 192130815 0.001969641 −46.33333333 Hypo-methylated PCa|NT DMRschr2 197501365 197501514 0.00064571  −34.76190476 Hypo-methylated PCa|NTDMRs chr2 198029845 198044986 1.97E−05 −54.38333333 Hypo-methylatedPCa|NT DMRs chr2 198455484 198455514 0.005968871 26.25714286Hyper-methylated PCa|NT DMRs chr2 198670398 198670628 0.00795910428.13877551 Hyper-methy lated PCa|NT DMRs chr2 203036152 2030380670.001189237 32.95918367 Hyper-methy lated PCa|NT DMRs chr2 204975155204975981 0.00064571  35.23129252 Hyper-methylated PCa|NT DMRs chr2206551075 206551748 0.000216661 28.54235589 Hyper-methy lated PCa|NTDMRs chr2 208372808 208393580 0.001037738 −35.16349206 Hypo-methylatedPCa|NT DMRs chr2 209248665 209257588 0.001171269 −21.49350649Hypo-methylated PCa|NT DMRs chr2 211633104 211790226 0.002097193−30.6122449 Hypo-methylated PCa|NT DMRs chr2 216870971 2168713740.00641359  39.62698413 Hyper-methylated PCa|NT DMRs chr2 217118607217118739 0.005968871 −44.12380952 Hypo-methylated PCa|NT DMRs chr2217501703 217502200 0.00064571  28.28911565 Hyper-methylated PCa|NT DMRschr2 218663904 218663979 0.005968871 49.86666667 Hyper-methy latedPCa|NT DMRs chr2 218809738 218845722 2.22E−05 −32.93371429Hypo-methylated PCa|NT DMRs chr2 218897690 218899361 0.00925585129.27647059 Hyper-methy lated PCa|NT DMRs chr2 219192754 2192036090.001509282 24.27919799 Hyper-methy lated PCa|NT DMRs chr2 219221846219222123 0.003448944 −32.59727891 Hypo-methylated PCa|NT DMRs chr2219266966 219268668 2.43E−07 −30.41380952 Hypo-methylated PCa|NT DMRschr2 219646460 219647412 2.98E−16 43.11980952 Hyper-methy lated PCa|NTDMRs chr2 220024466 220024769 0.000165902 −20.3040293 Hypo-methy latedPCa|NT DMRs chr2 220117660 220117987 1.37E−07 30.18047619Hyper-methylated PCa|NT DMRs chr2 220306200 220306250 0.00409567325.28571429 Hyper-methy lated PCa|NT DMRs chr2 220360817 2203616902.04E−06 24.5037518 Hyper-methylated PCa|NT DMRs chr2 220414026220416721 8.37E−05 25.59761905 Hyper-methylated PCa|NT DMRs chr2220439769 220457830 0.001709403 −24.09255952 Hypo-methylated PCa|NT DMRschr2 220493909 220493959 0.005968871 63.50285714 Hyper-methylated PCa|NTDMRs chr2 224904321 224904735 2.70E−07 30.70666667 Hyper-methylatedPCa|NT DMRs chr2 225266298 225266368 0.005968871 54.82857143Hyper-methylated PCa|NT DMRs chr2 225639605 225639745 0.00096726821.0952381 Hyper-methylated PCa|NT DMRs chr2 228028289 2280286495.82E−05 26.39285714 Hyper-methylated PCa|NT DMRs chr2 229120368229170764 3.66E−05 −30.24047619 Hypo-methylated PCa|NT DMRs chr2229326260 229879298 3.42E−13 −25.45393586 Hypo-methylated PCa|NT DMRschr2 230274961 230275101 0.005968871 −24.68571429 Hypo-methylated PCa|NTDMRs chr2 231524469 231525078 0.005968871 53.37142857 Hyper-methylatedPCa|NT DMRs chr2 231693254 231693446 0.000570487 20.78095238Hyper-methylated PCa|NT DMRs chr2 231732670 231734772 0.00596887121.78888889 Hyper-methylated PCa|NT DMRs chr2 231740522 2317431130.000729802 22.38888889 Hyper-methylated PCa|NT DMRs chr2 231809233231809291 0.001969641 22.42460317 Hyper-methylated PCa|NT DMRs chr2231854776 231855941 2.25E−13 21.24337194 Hyper-methylated PCa|NT DMRschr2 232055077 232055340 0.004231599 −22.38974359 Hypo-methylated PCa|NTDMRs chr2 232056484 232062135 7.31E−05 −22.88605442 Hypo-methylatedPCa|NT DMRs chr2 232186761 232186899 0.001969641 53.82619048Hyper-methylated PCa|NT DMRs chr2 232236067 232236424 0.00041808923.56065163 Hyper-methylated PCa|NT DMRs chr2 232253187 2322587620.008581782 31.26468254 Hyper-methylated PCa|NT DMRs chr2 232347993232354900 4.96E−07 35.86691087 Hyper-methylated PCa|NT DMRs chr2232425497 232428092 0.00641359  −39.16269841 Hypo-methylated PCa|NT DMRschr2 232479216 232480171 2.70E−14 37.56240079 Hyper-methylated PCa|NTDMRs chr2 233252274 233253378 4.72E−12 −33.79213732 Hypo-methylatedPCa|NT DMRs chr2 233285941 233286151 0.001083007 20.04047619 Hyper-methylated PCa|NT DMRs chr2 233312595 233312629 0.003448944 −21.06122449Hypo-methylated PCa|NT DMRs chr2 233498313 233500251 9.84E−1831.67488329 Hyper-methy lated PCa|NT DMRs chr2 233790639 2337918180.008897139 24.495671 Hyper-methylated PCa|NT DMRs chr2 233809607233815863 0.000205174 −22.36428571 Hypo-methy lated PCa|NT DMRs chr2233841555 233849331 6.04E−05 −30.19350649 Hypo-methy lated PCa|NT DMRschr2 233925165 233929137 3.34E−08 43.3358631 Hyper-methylated PCa|NTDMRs chr2 233943999 233950039 1.04E−05 26.41440186 Hyper-methylatedPCa|NT DMRs chr2 234062066 234072770 0.000481535 −23.85185185Hypo-methylated PCa|NT DMRs chr2 234180219 234198585 0.00064571 −44.50680272 Hypo-methylated PCa|NT DMRs chr2 234264046 2342837080.009195794 −22.14161491 Hypo-methylated PCa|NT DMRs chr2 234369848234370089 4.45E−08 −48.27428571 Hypo-methylated PCa|NT DMRs chr2234389588 234389764 0.004095673 −43.64285714 Hypo-methylated PCa|NT DMRschr2 234756972 234757125 0.001969641 30.23809524 Hyper-methylated PCa|NTDMRs chr2 235539582 235541338 0.001969641 −41.09444444 Hypo-methylatedPCa|NT DMRs chr2 235709338 235709681 0.000205174 −46.85535714Hypo-methylated PCa|NT DMRs chr2 235906815 235916154 0.006225823−23.54285714 Hypo-methylated PCa|NT DMRs chr2 235917354 2359178910.003622801 −34.34126984 Hypo-methylated PCa|NT DMRs chr2 235936118235936841 0.003056323 −43.5968254 Hypo-methylated PCa|NT DMRs chr2235961365 235961783 0.005968871 −40.33015873 Hypo-methylated PCa|NT DMRschr2 236474828 236475664 0.003391914 29.56878307 Hyper-methylated PCa|NTDMRs chr2 236961710 236963528 0.007840675 25.3358396 Hyper-methylatedPCa|NT DMRs chr2 237077414 237085816 1.81E−43 31.65858319Hyper-methylated PCa|NT DMRs chr2 237263701 237278472 0.001775064−42.91666667 Hypo-methylated PCa|NT DMRs chr2 237416056 2374161230.000481535 21.63492063 Hyper-methylated PCa|NT DMRs chr2 237476476237476892 1.25E−10 22.01142857 Hyper-methylated PCa|NT DMRs chr2237685525 237685823 0.001969641 −58.49206349 Hypo-methylated PCa|NT DMRschr2 237712355 237712492 0.005968871 32.99428571 Hyper-methylated PCa|NTDMRs chr2 237969260 237970369 0.001969641 −42.66111111 Hypo-methylatedPCa|NT DMRs chr2 238187125 238207725 0.000260936 −26.33952381Hypo-methylated PCa|NT DMRs chr2 238261903 238341455 3.21E−22−21.85297619 Hypo-methylated PCa|NT DMRs chr2 238359571 2383602551.97E−05 −22.82047619 Hypo-methylated PCa|NT DMRs chr2 238420737238433778 0.00032872  −23.68888889 Hypo-methylated PCa|NT DMRs chr2238642459 238644009 2.60E−05 −39.44255952 Hypo-methylated PCa|NT DMRschr2 238769342 238769420 0.004057568 −50.64285714 Hypo-methylated PCa|NTDMRs chr2 239017454 239023305 0.000513415 23.95816327 Hyper-methylatedPCa|NT DMRs chr2 239072275 239073970 4.02E−23 21.36383526Hyper-methylated PCa|NT DMRs chr2 239435070 239437807 0.001969641−30.43650794 Hypo-methylated PCa|NT DMRs chr2 239694252 2397054032.88E−05 −24.79254658 Hypo-methylated PCa|NT DMRs chr2 239837692239841275 4.63E−07 −20.71785714 Hypo-methylated PCa|NT DMRs chr2239981099 239981172 0.005968871 47.3952381 Hyper-methylated PCa|NT DMRschr2 239997573 239997951 0.000377317 −22.59702381 Hypo-methylated PCa|NTDMRs chr2 240076192 240076816 0.001160639 26.27142857 Hyper-methylatedPCa|NT DMRs chr2 240079628 240079717 0.005968871 −60.73333333Hypo-methylated PCa|NT DMRs chr2 240167680 240168313 1.66E−10−42.70238095 Hypo-methylated PCa|NT DMRs chr2 240187878 2401981620.006535327 24.36607143 Hyper-methylated PCa|NT DMRs chr2 240218300240218487 0.00641359  −28.45238095 Hypo-methylated PCa|NT DMRs chr2240238759 240239010 0.001969641 −47.6031746 Hypo-methylated PCa|NT DMRschr2 240270058 240270798 0.001083007 −35.08333333 Hypo-methylated PCa|NTDMRs chr2 240279807 240280163 0.001969641 −53.08231293 Hypo-methylatedPCa|NT DMRs chr2 240302429 240302645 0.00028029  34.85714286Hyper-methylated PCa|NT DMRs chr2 240361406 240383441 0.000231303−24.56122449 Hypo-methylated PCa|NT DMRs chr2 240383511 2403860851.95E−07 −27.98412698 Hypo-methylated PCa|NT DMRs chr2 240399323240410828 6.71E−09 −22.314518 Hypo-methylated PCa|NT DMRs chr2 240420347240421202 1.29E−06 −33.869161 Hypo-methylated PCa|NT DMRs chr2 240430671240451507 8.63E−13 −25.98992063 Hypo-methylated PCa|NT DMRs chr2240458193 240506049 6.60E−24 −27.07705106 Hypo-methylated PCa|NT DMRschr2 240515779 240518673 0.001344447 −39.29107143 Hypo-methylated PCa|NTDMRs chr2 240530602 240532221 1.97E−05 −31.06190476 Hypo-methylatedPCa|NT DMRs chr2 240567882 240568112 0.005438982 −26.56761905Hypo-methylated PCa|NT DMRs chr2 240586327 240593374 3.44E−06−30.60714286 Hypo-methylated PCa|NT DMRs chr2 240599941 2406196612.54E−07 −23.92113095 Hypo-methylated PCa|NT DMRs chr2 240658654240665479 7.52E−06 −23.83756614 Hypo-methylated PCa|NT DMRs chr2240672302 240672703 6.42E−05 −32.11111111 Hypo-methylated PCa|NT DMRschr2 240673060 240674119 2.52E−05 24.32773109 Hyper-methylated PCa|NTDMRs chr2 240689139 240689287 0.00064571  −34.46122449 Hypo-methylatedPCa|NT DMRs chr2 240698302 240731445 1.47E−16 −28.12758621Hypo-methylated PCa|NT DMRs chr2 240749506 240749872 0.005968871−41.74285714 Hypo-methylated PCa|NT DMRs chr2 240985852 2410109280.00013778  −27.13003663 Hypo-methylated PCa|NT DMRs chr2 241190512241190982 0.000695921 −34.98746867 Hypo-methylated PCa|NT DMRs chr2241287924 241293252 6.77E−05 −21.2873706 Hypo-methylated PCa|NT DMRschr2 241303199 241304062 0.000564835 −27.1 Hypo-methylated PCa|NT DMRschr2 241317552 241323074 2.86E−05 −22.61538462 Hypo-methylated PCa|NTDMRs chr2 241333368 241337189 0.000215808 −31.76984127 Hypo-methylatedPCa|NT DMRs chr2 241387484 241387957 0.000365371 −23.93613445Hypo-methylated PCa|NT DMRs chr2 241562086 241564964 1.09E−1042.56785714 Hyper-methylated PCa|NT DMRs chr2 241775840 2417957560.000614706 −22.58116883 Hypo-methylated PCa|NT DMRs chr2 241853025241854588 6.69E−05 −49.19761905 Hypo-methylated PCa|NT DMRs chr2241855280 241856157 0.00034072  26.78151261 Hyper-methylated PCa|NT DMRschr2 241904140 241905740 1.52E−06 30.23870968 Hyper-methylated PCa|NTDMRs chr2 241930909 241931550 3.81E−05 −42.8012987 Hypo-methylatedPCa|NT DMRs chr2 242031375 242034103 0.001083007 −29.84190476Hypo-methylated PCa|NT DMRs chr2 242063157 242065890 0.00128874 −41.05194805 Hypo-methylated PCa|NT DMRs chr2 242127948 2421289308.23E−07 −34.48819048 Hypo-methylated PCa|NT DMRs chr2 242139786242141146 1.45E−07 25.54489796 Hyper-methylated PCa|NT DMRs chr2242195217 242209595 0.000847246 −28.44659864 Hypo-methylated PCa|NT DMRschr2 242448612 242448879 0.000215808 22.02116402 Hyper-methylated PCa|NTDMRs chr2 242480249 242480505 3.36E−06 22.03726708 Hyper-methylatedPCa|NT DMRs chr2 242489719 242490335 0.001789867 −36.03968254Hypo-methylated PCa|NT DMRs chr2 242602177 242605056 8.39E−05−24.7605042 Hypo-methylated PCa|NT DMRs chr2 242702750 2427068890.000166226 33.25824176 Hyper-methylated PCa|NT DMRs chr2 242713019242713689 0.004162937 −32.56904762 Hypo-methylated PCa|NT DMRs chr2242713751 242713888 0.002534928 28.53809524 Hyper-methylated PCa|NT DMRschr2 242743649 242744590 1.66E−07 29.56568144 Hyper-methylated PCa|NTDMRs chr2 242763866 242764069 0.005295761 28.37662338 Hyper-methylatedPCa|NT DMRs chr2 242774275 242776222 0.004231599 −20.69267399Hypo-methylated PCa|NT DMRs chr2 242784847 242786128 7.01E−0941.80367347 Hyper-methylated PCa|NT DMRs chr2 242794855 2427949811.69E−06 −26.48711485 Hypo-methylated PCa|NT DMRs chr2 242805857242810434 0.000104747 23.99085213 Hyper-methylated PCa|NT DMRs chr2242829929 242834690 4.29E−06 −40.41981982 Hypo-methylated PCa|NT DMRschr2 242843822 242844721 6.54E−11 21.08558559 Hyper-methylated PCa|NTDMRs chr2 242927565 242927898 2.11E−06 36.92559524 Hyper-methylatedPCa|NT DMRs chr2 242946990 242947347 0.000209339 −33.80952381Hypo-methylated PCa|NT DMRs chr3 2189939 2192851 0.00064571 −30.58503401 Hypo-methylated PCa|NT DMRs chr3 3840551 3840913 5.41E−0924.50095238 Hyper-methylated PCa|NT DMRs chr3 4345887 43459190.005968871 −32.64 Hypo-methylated PCa|NT DMRs chr3 5141437 51556200.001789867 −23.59259259 Hypo-methylated PCa|NT DMRs chr3 66540496715713 0.001969641 −30.27698413 Hypo-methylated PCa|NT DMRs chr39222564 9222873 0.005968871 59.79428571 Hyper-methylated PCa|NT DMRschr3 9771218 9771280 0.001969641 −31.57142857 Hypo-methylated PCa|NTDMRs chr3 9884796 9884931 0.000118316 −22.51785714 Hypo-methylatedPCa|NT DMRs chr3 9987430 9996973 6.59E−11 −28.9437996 Hypo-methylatedPCa|NT DMRs chr3 10206210 10206259 0.003622801 −25.16666667Hypo-methylated PCa|NT DMRs chr3 10325249 10325495 0.005968871−37.36190476 Hypo-methylated PCa|NT DMRs chr3 10352032 10354338 1.43E−06−27.50793651 Hypo-methylated PCa|NT DMRs chr3 10370439 103716650.000111427 −28.26904762 Hypo-methylated PCa|NT DMRs chr3 1065108810662428 0.001013662 −20.91666667 Hypo-methylated PCa|NT DMRs chr310805784 10806395 0.000109295 22.54458874 Hyper-methylated PCa|NT DMRschr3 10987978 10992387 0.007628253 −31.56462585 Hypo-methylated PCa|NTDMRs chr3 11035187 11035383 7.88E−06 22.11160714 Hyper-methylated PCa|NTDMRs chr3 11102832 11103118 0.0005791  −27.73669468 Hypo-methylatedPCa|NT DMRs chr3 11267851 11284261 0.000377317 −22.63214286Hypo-methylated PCa|NT DMRs chr3 11303244 11309033 0.005968871−34.23714286 Hypo-methylated PCa|NT DMRs chr3 12111766 121120290.001969641 −30.08730159 Hypo-methylated PCa|NT DMRs chr3 1258606812592851 0.001969641 −33.34285714 Hypo-methylated PCa|NT DMRs chr312966141 12966358 0.00179283  27.11428571 Hyper-methylated PCa|NT DMRschr3 13082454 13082682 0.005513661 32.42517007 Hyper-methylated PCa|NTDMRs chr3 13107889 13107931 0.001969641 38.4047619 Hyper-methylatedPCa|NT DMRs chr3 13134381 13134439 0.00064571  −43.2244898Hypo-methylated PCa|NT DMRs chr3 13153914 13153995 0.005968871 −54.6Hypo-methylated PCa|NT DMRs chr3 13163633 13164899 0.008581782−22.26785714 Hypo-methylated PCa|NT DMRs chr3 13261052 13261521 3.87E−05−29.15686275 Hypo-methylated PCa|NT DMRs chr3 13295875 132963680.001789867 21.97089947 Hyper-methylated PCa|NT DMRs chr3 1332275513324142 1.35E−12 29.0487619 Hyper-methylated PCa|NT DMRs chr3 1345355613454895 0.005968871 −29.97142857 Hypo-methylated PCa|NT DMRs chr313456129 13460374 0.000172237 36.15136054 Hyper-methylated PCa|NT DMRschr3 13535801 13536396 0.003622801 −24.82142857 Hypo-methylated PCa|NTDMRs chr3 13590903 13595543 0.00068166  21.76329365 Hyper-methylatedPCa|NT DMRs chr3 13634770 13648506 0.000145812 −25.45684524Hypo-methylated PCa|NT DMRs chr3 13696498 13696590 0.00111530231.79285714 Hyper-methylated PCa|NT DMRs chr3 13886422 13906816 6.73E−09−29.0985843 Hypo-methylated PCa|NT DMRs chr3 14347416 143497010.002767976 −26.77359307 Hypo-methylated PCa|NT DMRs chr3 1435111214359347 0.000840726 24.59365079 Hyper-methylated PCa|NT DMRs chr314494726 14494916 0.001969641 −59.59183673 Hypo-methylated PCa|NT DMRschr3 14597401 14597677 2.14E−08 48.06948854 Hyper-methylated PCa|NT DMRschr3 14852520 14852812 9.95E−11 20.65414966 Hyper-methylated PCa|NT DMRschr3 14944084 14962565 0.000440405 −27.13157895 Hypo-methylated PCa|NTDMRs chr3 16359535 16359699 0.005968871 51.98571429 Hyper-methylatedPCa|NT DMRs chr3 16572713 16625310 6.90E−06 −31.86904762 Hypo-methylatedPCa|NT DMRs chr3 16661170 16811682 5.94E−06 −42.17316017 Hypo-methylatedPCa|NT DMRs chr3 19777033 19870137 4.90E−08 −27.9534632 Hypo-methylatedPCa|NT DMRs chr3 20409494 20475035 1.03E−05 −34.93095238 Hypo-methylatedPCa|NT DMRs chr3 21095717 21267469 5.53E−08 −31.78181818 Hypo-methylatedPCa|NT DMRs chr3 22458288 22868648 2.49E−12 −36.17619048 Hypo-methylatedPCa|NT DMRs chr3 23784649 23785077 4.90E−08 −45.83441558 Hypo-methylatedPCa|NT DMRs chr3 24563543 24563856 0.000196301 33.91666667Hyper-methylated PCa|NT DMRs chr3 25788413 25822319 0.00139142124.56623377 Hyper-methylated PCa|NT DMRs chr3 27830321 278570160.003448944 −26.16258503 Hypo-methylated PCa|NT DMRs chr3 3232497132325053 0.005968871 28.54285714 Hyper-methylated PCa|NT DMRs chr332542453 32542607 0.002534928 37.9 Hyper-methylated PCa|NT DMRs chr333806130 33819158 0.002097193 −38.67006803 Hypo-methylated PCa|NT DMRschr3 33923352 33997649 0.000392715 −21.95047619 Hypo-methylated PCa|NTDMRs chr3 35749002 36384340 6.29E−12 −29.0510989 Hypo-methylated PCa|NTDMRs chr3 36433155 36581379 5.52E−06 −23.97117794 Hypo-methylated PCa|NTDMRs chr3 36805618 36805655 0.001969641 30.5 Hyper-methylated PCa|NTDMRs chr3 36873851 36874173 0.001451132 −22.87301587 Hypo-methylatedPCa|NT DMRs chr3 38022164 38036310 8.69E−06 21.08294574 Hyper-methylatedPCa|NT DMRs chr3 38080673 38081695 1.94E−17 27.74231806 Hyper-methylatedPCa|NT DMRs chr3 38157991 38158048 0.005968871 −43.20952381Hypo-methylated PCa|NT DMRs chr3 38698863 38768663 5.42E−07 −40.19312169Hypo-methylated PCa|NT DMRs chr3 38793972 38980352 3.13E−09 −37.34479718Hypo-methylated PCa|NT DMRs chr3 39184553 39185795 7.95E−05 −35.25824176Hypo-methylated PCa|NT DMRs chr3 40368753 40368789 0.005968871−37.45714286 Hypo-methylated PCa|NT DMRs chr3 40656796 40657331 9.46E−0531.07969925 Hyper-methylated PCa|NT DMRs chr3 40821888 408229060.001115302 −39.56547619 Hypo-methylated PCa|NT DMRs chr3 4200534542008186 0.005513661 −21.17857143 Hypo-methylated PCa|NT DMRs chr342568067 42568556 0.000294557 24.74199134 Hyper-methylated PCa|NT DMRschr3 42586344 42586708 0.00023371  −58.84285714 Hypo-methylated PCa|NTDMRs chr3 42740568 42740650 0.005968871 41.71428571 Hyper-methylatedPCa|NT DMRs chr3 42947590 42947903 1.02E−12 24.24350064 Hyper-methylatedPCa|NT DMRs chr3 43037037 43049564 0.002437742 −26.65925926Hypo-methylated PCa|NT DMRs chr3 43830160 43862874 0.00179283 −20.26785714 Hypo-methylated PCa|NT DMRs chr3 44069059 440759980.001969641 −22.5 Hypo-methylated PCa|NT DMRs chr3 45821493 458216930.005513661 −26.69047619 Hypo-methylated PCa|NT DMRs chr3 4600928846009664 0.001969641 −47.07142857 Hypo-methylated PCa|NT DMRs chr346607381 46607468 0.008482405 29.8 Hyper-methylated PCa|NT DMRs chr346735437 46735616 0.009069241 28.57142857 Hyper-methylated PCa|NT DMRschr3 46853817 46853972 0.002243506 21.71212121 Hyper-methylated PCa|NTDMRs chr3 47029398 47029597 0.000205174 44.7952381 Hyper-methylatedPCa|NT DMRs chr3 48131229 48131298 0.002097193 −30.12244898Hypo-methylated PCa|NT DMRs chr3 48283597 48283898 0.007560755−29.04166667 Hypo-methylated PCa|NT DMRs chr3 48598501 485989780.001969641 35.64285714 Hyper-methylated PCa|NT DMRs chr3 4863225048633317 7.15E−06 29.76642857 Hyper-methylated PCa|NT DMRs chr3 4863627748636596 0.000305995 −39.5 Hypo-methylated PCa|NT DMRs chr3 4874647648750172 0.005438982 −23.94285714 Hypo-methylated PCa|NT DMRs chr348883897 48884081 0.000377317 −24.51845238 Hypo-methylated PCa|NT DMRschr3 49705312 49705658 0.000157125 −27.31809524 Hypo-methylated PCa|NTDMRs chr3 50311119 50314337 1.66E−25 37.18675856 Hyper-methylated PCa|NTDMRs chr3 50567634 50568126 1.91E−08 21.67676768 Hyper-methylated PCa|NTDMRs chr3 50625996 50637484 0.006410012 30.75288221 Hyper-methylatedPCa|NT DMRs chr3 50643197 50645354 1.00E−05 25.99174603 Hyper-methylatedPCa|NT DMRs chr3 51671285 51671477 0.003448944 −21.23260073Hypo-methylated PCa|NT DMRs chr3 52224975 52227349 0.000168936−47.19264069 Hypo-methylated PCa|NT DMRs chr3 52351836 52351956 3.43E−0642.54464286 Hyper-methylated PCa|NT DMRs chr3 52472027 524721190.001969641 −48.13605442 Hypo-methylated PCa|NT DMRs chr3 5250091152505893 0.000243521 −39.60779221 Hypo-methylated PCa|NT DMRs chr352524840 52525480 0.000266785 25.67962963 Hyper-methylated PCa|NT DMRschr3 52529132 52529760 8.76E−09 36.61581633 Hyper-methylated PCa|NT DMRschr3 52565909 52567260 0.001289384 24.57635468 Hyper-methylated PCa|NTDMRs chr3 52568571 52568729 0.00023371  −20.18571429 Hypo-methylatedPCa|NT DMRs chr3 53080649 53081278 9.01E−08 22.78354978 Hyper-methylatedPCa|NT DMRs chr3 53709966 53740155 0.00248539  26.5452381Hyper-methylated PCa|NT DMRs chr3 54157600 54157745 0.00246339920.32467532 Hyper-methylated PCa|NT DMRs chr3 54597851 545979870.007628253 −39.92517007 Hypo-methylated PCa|NT DMRs chr3 5613562856135965 0.005968871 37.08095238 Hyper-methylated PCa|NT DMRs chr356717505 56717770 0.000443725 −27.21496599 Hypo-methylated PCa|NT DMRschr3 57945651 57945743 0.005968871 34.22857143 Hyper-methylated PCa|NTDMRs chr3 57996569 58006904 0.000205174 −52.71428571 Hypo-methylatedPCa|NT DMRs chr3 58107099 58107183 0.001969641 −27.28571429Hypo-methylated PCa|NT DMRs chr3 58163925 58163998 0.00978774529.19428571 Hyper-methylated PCa|NT DMRs chr3 58572635 58572808 6.29E−0933.29395604 Hyper-methylated PCa|NT DMRs chr3 58645085 586454030.004376829 −45.65608466 Hypo-methylated PCa|NT DMRs chr3 6154913761549449 4.09E−07 38.28320802 Hyper-methylated PCa|NT DMRs chr3 6389905463899382 0.000696555 −23.26017316 Hypo-methylated PCa|NT DMRs chr364210992 64253866 4.83E−09 36.58131868 Hyper-methylated PCa|NT DMRs chr365317166 65356001 4.35E−13 38.25769231 Hyper-methylated PCa|NT DMRs chr366452406 66453560 0.000118733 −31.40687831 Hypo-methylated PCa|NT DMRschr3 66831353 66939121 0.000136892 26.63238095 Hyper-methylated PCa|NTDMRs chr3 67706348 67706568 5.84E−05 58.26587302 Hyper-methylated PCa|NTDMRs chr3 69061575 69061831 0.005968871 −33.2 Hypo-methylated PCa|NTDMRs chr3 69230383 69251212 0.000826653 −32.39166667 Hypo-methylatedPCa|NT DMRs chr3 71410847 71411051 0.001969641 −34.5952381Hypo-methylated PCa|NT DMRs chr3 71981727 72033362 0.00641359 −29.58333333 Hypo-methylated PCa|NT DMRs chr3 72202300 722116310.004947537 −38.76455026 Hypo-methylated PCa|NT DMRs chr3 7278801572788226 3.91E−07 32.92205514 Hyper-methylated PCa|NT DMRs chr3 7356398173570326 0.005968871 −50.0952381 Hypo-methylated PCa|NT DMRs chr374000093 74080135 1.10E−05 −20.56164021 Hypo-methylated PCa|NT DMRs chr375191507 75263736 6.42E−05 −28.83862434 Hypo-methylated PCa|NT DMRs chr375376761 75412696 9.09E−06 −29.89071429 Hypo-methylated PCa|NT DMRs chr375495819 75556133 4.29E−08 −22.72721088 Hypo-methylated PCa|NT DMRs chr375861114 75871514 0.001969641 −34.51984127 Hypo-methylated PCa|NT DMRschr3 79188728 79333142 4.20E−07 −20.44679089 Hypo-methylated PCa|NT DMRschr3 79556294 79708316 1.76E−06 −27.47063492 Hypo-methylated PCa|NT DMRschr3 80394942 80479627 6.94E−06 −27.56031746 Hypo-methylated PCa|NT DMRschr3 80931665 81228753 4.69E−12 −32.26353078 Hypo-methylated PCa|NT DMRschr3 81312941 81525412 1.48E−07 −27.5995671 Hypo-methylated PCa|NT DMRschr3 81816604 81881850 1.00E−08 −23.95805861 Hypo-methylated PCa|NT DMRschr3 82160140 82555783 1.07E−10 −30.06040816 Hypo-methylated PCa|NT DMRschr3 82690498 82923743 1.04E−12 −31.06679537 Hypo-methylated PCa|NT DMRschr3 83324209 84144425 4.72E−16 −34.1669088 Hypo-methylated PCa|NT DMRschr3 84174379 84549910 4.21E−14 −32.90931677 Hypo-methylated PCa|NT DMRschr3 84597769 84622970 0.008482405 −34.69714286 Hypo-methylated PCa|NTDMRs chr3 87138203 87138521 1.52E−08 43.65520282 Hyper-methylated PCa|NTDMRs chr3 88244957 89113736 2.92E−14 −32.15160173 Hypo-methylated PCa|NTDMRs chr3 93882885 93897493 0.004095673 −52.37222222 Hypo-methylatedPCa|NT DMRs chr3 97770314 98030112 1.87E−05 −27.21428571 Hypo-methylatedPCa|NT DMRs chr3 98613529 98613594 0.005968871 −29.28571429Hypo-methylated PCa|NT DMRs chr3 99381532 99419185 0.001171269−27.82207792 Hypo-methylated PCa|NT DMRs chr3 100526581 1006585226.42E−05 −40.7962963 Hypo-methylated PCa|NT DMRs chr3 101396737101402717 3.16E−07 −42.93469388 Hypo-methylated PCa|NT DMRs chr3102642298 102678691 0.000339087 −24.6957672 Hypo-methylated PCa|NT DMRschr3 103012414 103749921 2.94E−14 −31.15238095 Hypo-methylated PCa|NTDMRs chr3 107675880 107712051 0.001430886 −33.03571429 Hypo-methylatedPCa|NT DMRs chr3 108434212 108599282 1.41E−05 −28.54455782Hypo-methylated PCa|NT DMRs chr3 108616526 108735432 3.44E−06−35.72142857 Hypo-methylated PCa|NT DMRs chr3 108835484 1090549251.61E−24 −28.07724868 Hypo-methylated PCa|NT DMRs chr3 109059738109068430 0.000118733 −26.98677249 Hypo-methylated PCa|NT DMRs chr3109080333 109110314 0.001344447 −39.64702381 Hypo-methylated PCa|NT DMRschr3 109129857 109404368 2.86E−09 −30.63218391 Hypo-methylated PCa|NTDMRs chr3 111410981 111411091 5.52E−05 −33.09307359 Hypo-methylatedPCa|NT DMRs chr3 112052124 112053518 4.56E−10 28.44162826Hyper-methylated PCa|NT DMRs chr3 112357212 112510113 9.64E−14−39.12590012 Hypo-methylated PCa|NT DMRs chr3 112936919 1129430150.005513661 29.30952381 Hyper-methylated PCa|NT DMRs chr3 113160075113160706 5.14E−08 26.68973214 Hyper-methylated PCa|NT DMRs chr3116742526 116742590 0.005968871 40.64761905 Hyper-methylated PCa|NT DMRschr3 116990369 117193182 0.001969641 −35.84603175 Hypo-methylated PCa|NTDMRs chr3 117733238 118730168 5.46E−37 −31.16159251 Hypo-methylatedPCa|NT DMRs chr3 118791508 118858083 6.84E−10 −25.63065476Hypo-methylated PCa|NT DMRs chr3 119697546 119697780 0.007679542−25.56243386 Hypo-methylated PCa|NT DMRs chr3 120157815 1201579950.001969641 −56.78571429 Hypo-methylated PCa|NT DMRs chr3 120170040120170425 2.04E−05 22.77800454 Hyper-methylated PCa|NT DMRs chr3122234462 122234498 0.005968871 −36.07619048 Hypo-methylated PCa|NT DMRschr3 123432259 123439101 1.97E−05 −43.48809524 Hypo-methylated PCa|NTDMRs chr3 124781735 124782070 0.007233677 −40.85416667 Hypo-methylatedPCa|NT DMRs chr3 125123729 125123874 0.005968871 −22.88571429Hypo-methylated PCa|NT DMRs chr3 125480002 125482262 0.00733875721.17857143 Hyper-methylated PCa|NT DMRs chr3 125898944 1259000663.76E−21 21.58427318 Hyper-methylated PCa|NT DMRs chr3 125989071125989239 0.005968871 −55.82857143 Hypo-methylated PCa|NT DMRs chr3126135364 126135401 0.008482405 44.07904762 Hyper-methylated PCa|NT DMRschr3 126248069 126248458 0.004095673 41.41269841 Hyper-methylated PCa|NTDMRs chr3 126260408 126261355 9.01E−14 −22.4850686 Hypo-methylatedPCa|NT DMRs chr3 126381917 126381952 0.007560755 −41.79464286Hypo-methylated PCa|NT DMRs chr3 126860805 126861412 0.001969641−40.46031746 Hypo-methylated PCa|NT DMRs chr3 127069800 1270698770.002826041 27.25034014 Hyper-methylated PCa|NT DMRs chr3 127175083127175137 0.00064571  22.21164021 Hyper-methylated PCa|NT DMRs chr3127266365 127266500 0.000363161 25.38392857 Hyper-methylated PCa|NT DMRschr3 127439424 127441768 2.05E−05 −27.01082251 Hypo-methylated PCa|NTDMRs chr3 127633608 127633888 0.001083007 −40.62142857 Hypo-methylatedPCa|NT DMRs chr3 127634527 127634587 0.001419801 27.93888889Hyper-methylated PCa|NT DMRs chr3 127634788 127693494 0.001969641−22.8531746 Hypo-methylated PCa|NT DMRs chr3 127954900 1279574920.005513661 21.44642857 Hyper-methylated PCa|NT DMRs chr3 128001142128001759 1.76E−06 −56.41349206 Hypo-methylated PCa|NT DMRs chr3128123108 128123259 0.000974795 −27.67857143 Hypo-methylated PCa|NT DMRschr3 128274726 128276076 0.008109221 39.27142857 Hyper-methylated PCa|NTDMRs chr3 128294897 128295135 0.001969641 −22.06746032 Hypo-methylatedPCa|NT DMRs chr3 128307104 128326680 2.58E−05 30.41415701Hyper-methylated PCa|NT DMRs chr3 128370457 128371298 0.00529576129.63419913 Hyper-methylated PCa|NT DMRs chr3 128567687 1285686120.002097193 −30.37687075 Hypo-methylated PCa|NT DMRs chr3 128710421128710530 0.001969641 51.20873016 Hyper-methylated PCa|NT DMRs chr3129295896 129297909 0.000754912 44.79714286 Hyper-methylated PCa|NT DMRschr3 129337801 129338205 1.66E−05 38.16246499 Hyper-methylated PCa|NTDMRs chr3 129342553 129342702 1.27E−08 −61.62291667 Hypo-methylatedPCa|NT DMRs chr3 132624879 132728974 7.57E−05 −26.79722222Hypo-methylated PCa|NT DMRs chr3 132922215 133099864 0.000648693−25.03968254 Hypo-methylated PCa|NT DMRs chr3 133291052 1332911160.005968871 42.4 Hyper-methylated PCa|NT DMRs chr3 133464950 1334653871.34E−12 31.22015504 Hyper-methylated PCa|NT DMRs chr3 133661523133661586 0.008482405 57.62857143 Hyper-methylated PCa|NT DMRs chr3134077285 134089922 4.20E−07 34.46696429 Hyper-methylated PCa|NT DMRschr3 134378765 134513435 4.79E−08 −28.46850998 Hypo-methylated PCa|NTDMRs chr3 134523940 135582304 2.59E−28 −28.69820566 Hypo-methylatedPCa|NT DMRs chr3 137487843 137490651 4.97E−30 21.44655522Hyper-methylated PCa|NT DMRs chr3 137920396 137920465 0.00064571 −25.71428571 Hypo-methylated PCa|NT DMRs chr3 138154011 1381547382.06E−08 27.51972789 Hyper-methylated PCa|NT DMRs chr3 138608383138628551 0.001460345 20.91904762 Hyper-methylated PCa|NT DMRs chr3138654723 138654889 0.003622801 36.02380952 Hyper-methylated PCa|NT DMRschr3 140513452 140552250 0.005968871 28.82275132 Hyper-methylated PCa|NTDMRs chr3 140949414 140950323 2.99E−05 21.14234234 Hyper-methylatedPCa|NT DMRs chr3 141087119 141087314 6.38E−06 −39.4 Hypo-methylatedPCa|NT DMRs chr3 141380054 141380400 0.001969641 28.36031746Hyper-methylated PCa|NT DMRs chr3 141989206 141989938 0.00409567332.18253968 Hyper-methylated PCa|NT DMRs chr3 142443823 1424439346.42E−05 21.32010582 Hyper-methylated PCa|NT DMRs chr3 142895178142895211 0.005968871 −51.82857143 Hypo-methylated PCa|NT DMRs chr3144509945 144818559 6.68E−10 −32.58180272 Hypo-methylated PCa|NT DMRschr3 145249570 145378745 0.005513661 −30.57687075 Hypo-methylated PCa|NTDMRs chr3 147290242 147580795 1.23E−07 −37.58550725 Hypo-methylatedPCa|NT DMRs chr3 147706513 147776676 7.55E−05 −27.39598997Hypo-methylated PCa|NT DMRs chr3 147998621 147998677 0.000205174−29.99345238 Hypo-methylated PCa|NT DMRs chr3 149261225 1492653700.00023371  −30.05714286 Hypo-methylated PCa|NT DMRs chr3 152821757152821793 0.005968871 34.58 Hyper-methylated PCa|NT DMRs chr3 156009117156009490 9.92E−08 24.39160998 Hyper-methylated PCa|NT DMRs chr3156533849 156534411 1.67E−10 29.01267281 Hyper-methylated PCa|NT DMRschr3 156827612 156843435 0.000149331 −34.85357143 Hypo-methylated PCa|NTDMRs chr3 159725550 159725722 0.00064571  −35.44897959 Hypo-methylatedPCa|NT DMRs chr3 159942271 159943073 8.98E−05 21.94404762Hyper-methylated PCa|NT DMRs chr3 163285117 163643541 1.67E−10−29.62596006 Hypo-methylated PCa|NT DMRs chr3 163726905 1640295169.82E−07 −28.14616977 Hypo-methylated PCa|NT DMRs chr3 164436187164537373 3.94E−09 −24.6079932 Hypo-methylated PCa|NT DMRs chr3164583687 164588390 1.67E−08 −32.02539683 Hypo-methylated PCa|NT DMRschr3 164912468 164912554 0.002097193 25.46122449 Hyper-methylated PCa|NTDMRs chr3 164923574 164989437 0.005968871 −28.83809524 Hypo-methylatedPCa|NT DMRs chr3 166984456 166984739 0.000205174 −25.83928571Hypo-methylated PCa|NT DMRs chr3 167126693 167377217 0.001969641−29.18650794 Hypo-methylated PCa|NT DMRs chr3 168005442 1688342692.31E−13 −28.96774892 Hypo-methylated PCa|NT DMRs chr3 169129528169362341 6.77E−09 −28.18752053 Hypo-methylated PCa|NT DMRs chr3169376578 169379504 6.78E−07 26.66363636 Hyper-methylated PCa|NT DMRschr3 169719911 169720363 0.001291665 33.6991342 Hyper-methylated PCa|NTDMRs chr3 170745826 170746208 0.000277103 40.18315018 Hyper-methylatedPCa|NT DMRs chr3 171175816 171176142 2.86E−05 45.59340659Hyper-methylated PCa|NT DMRs chr3 171846800 171854790 0.00600692328.91680672 Hyper-methylated PCa|NT DMRs chr3 172618473 1728812137.58E−07 −24.47204969 Hypo-methylated PCa|NT DMRs chr3 172993980173030958 0.003290817 −24.49642857 Hypo-methylated PCa|NT DMRs chr3177310875 177311090 0.003871035 −26.68154762 Hypo-methylated PCa|NT DMRschr3 179182653 179182799 0.005968871 45.27619048 Hyper-methylated PCa|NTDMRs chr3 179280026 179280075 0.001969641 −43.23809524 Hypo-methylatedPCa|NT DMRs chr3 180588007 180588082 0.000205174 26.35714286Hyper-methylated PCa|NT DMRs chr3 181413070 181414195 3.74E−1226.01486643 Hyper-methylated PCa|NT DMRs chr3 183258704 1832727232.52E−05 35.58403361 Hyper-methylated PCa|NT DMRs chr3 183542549183542851 8.68E−12 23.00225564 Hyper-methylated PCa|NT DMRs chr3183913838 183925396 0.000696555 −20.03896104 Hypo-methylated PCa|NT DMRschr3 184277166 184277439 0.005968871 −45.54285714 Hypo-methylated PCa|NTDMRs chr3 184280190 184280945 3.08E−06 −29.04702381 Hypo-methylatedPCa|NT DMRs chr3 184404896 184405563 0.007679542 34.01111111Hyper-methylated PCa|NT DMRs chr3 184893503 184893781 0.00551366137.23469388 Hyper-methylated PCa|NT DMRs chr3 186490372 1864907912.41E−08 43.01573499 Hyper-methylated PCa|NT DMRs chr3 186542783186543274 0.000575877 29.24632035 Hyper-methylated PCa|NT DMRs chr3186822222 186844110 0.001789867 −41.83280423 Hypo-methylated PCa|NT DMRschr3 187676564 187683317 0.004629421 49.9952381 Hyper-methylated PCa|NTDMRs chr3 188012863 188012956 0.005968871 −50.23333333 Hypo-methylatedPCa|NT DMRs chr3 191167788 191661655 8.95E−16 −33.16402116Hypo-methylated PCa|NT DMRs chr3 192530105 192623547 9.33E−10−28.51970443 Hypo-methylated PCa|NT DMRs chr3 192670735 1927517620.00015808  −30.85612245 Hypo-methylated PCa|NT DMRs chr3 192760612192943009 4.14E−08 −35.67043651 Hypo-methylated PCa|NT DMRs chr3192974771 193218451 8.70E−08 −32.08710317 Hypo-methylated PCa|NT DMRschr3 193576680 193599889 1.42E−07 28.88779762 Hyper-methylated PCa|NTDMRs chr3 193661153 193661325 0.001969641 −30.45634921 Hypo-methylatedPCa|NT DMRs chr3 193755127 193788568 2.58E−07 31.84500768Hyper-methylated PCa|NT DMRs chr3 193983048 193983157 0.001969641−21.97959184 Hypo-methylated PCa|NT DMRs chr3 194018000 1940182091.97E−05 47.22619048 Hyper-methylated PCa|NT DMRs chr3 194034015194034113 0.00068166  23.18452381 Hyper-methylated PCa|NT DMRs chr3194116989 194118924 3.32E−14 40.01227513 Hyper-methylated PCa|NT DMRschr3 194845951 194865631 0.009050681 20.45714286 Hyper-methylated PCa|NTDMRs chr3 194899525 194907898 0.0029761  27.63406593 Hyper-methylatedPCa|NT DMRs chr3 195488494 195490917 6.49E−06 20.99220779Hyper-methylated PCa|NT DMRs chr3 195566483 195570580 0.000777687−22.31428571 Hypo-methylated PCa|NT DMRs chr3 195583593 1955866650.002585277 46.58630952 Hyper-methylated PCa|NT DMRs chr3 195682379195685848 0.000398029 35.91208791 Hyper-methylated PCa|NT DMRs chr3195749097 195753109 0.002193447 −33.395671 Hypo-methylated PCa|NT DMRschr3 195920950 195921816 0.007338757 30.24404762 Hyper-methylated PCa|NTDMRs chr3 195929165 195929663 0.000339627 29.575 Hyper-methylated PCa|NTDMRs chr3 195942925 195943487 2.65E−07 −40.02142857 Hypo-methylatedPCa|NT DMRs chr3 195947033 195948885 0.007991909 24.00805861Hyper-methylated PCa|NT DMRs chr3 195950175 195950324 0.001969641 −50Hypo-methylated PCa|NT DMRs chr3 196187786 196187834 0.005968871−36.22857143 Hypo-methylated PCa|NT DMRs chr3 196367507 1963678336.93E−06 49.64761905 Hyper-methylated PCa|NT DMRs chr3 196387377196393760 9.49E−05 −39.3967033 Hypo-methylated PCa|NT DMRs chr3196397715 196399708 0.007628253 −21.14965986 Hypo-methylated PCa|NT DMRschr3 196716852 196717004 0.001181579 −40.49387755 Hypo-methylated PCa|NTDMRs chr3 196738019 196738112 0.005968871 −43.44761905 Hypo-methylatedPCa|NT DMRs chr3 197081608 197081754 0.000205174 −34.03571429Hypo-methylated PCa|NT DMRs chr3 197260360 197260527 0.00196964141.52040816 Hyper-methylated PCa|NT DMRs chr3 197263525 1972670310.001775064 −45.94047619 Hypo-methylated PCa|NT DMRs chr3 197269671197269871 0.00064571  39.08503401 Hyper-methylated PCa|NT DMRs chr3197326607 197327213 0.000601868 −20.30782313 Hypo-methylated PCa|NT DMRschr3 197364016 197365314 0.005257942 23.72825397 Hyper-methylated PCa|NTDMRs chr3 197678267 197684523 0.001480644 −37.46095238 Hypo-methylatedPCa|NT DMRs chr4 382667 383850 0.001969641 −33.11746032 Hypo-methylatedPCa|NT DMRs chr4 583022 585254 0.008482405 −24.05714286 Hypo-methylatedPCa|NT DMRs chr4 601111 606632 9.23E−05 −25.72521008 Hypo-methylatedPCa|NT DMRs chr4 658691 666698 5.65E−13 −23.05869565 Hypo-methylatedPCa|NT DMRs chr4 684991 686987 0.000325529 −32.9047619 Hypo-methylatedPCa|NT DMRs chr4 720211 720653 0.005513661 31.87278912 Hyper-methylatedPCa|NT DMRs chr4 778703 781744 5.70E−22 34.84824659 Hyper-methylatedPCa|NT DMRs chr4 827973 828360 3.52E−06 −20.64393241 Hypo-methylatedPCa|NT DMRs chr4 942132 942382 0.001480644 −22.68571429 Hypo-methylatedPCa|NT DMRs chr4 961400 962298 7.98E−08 23.56616008 Hyper-methylatedPCa|NT DMRs chr4 972502 973371 0.000179749 39.76817043 Hyper-methylatedPCa|NT DMRs chr4 997048 997871 3.53E−08 23.85668203 Hyper-methylatedPCa|NT DMRs chr4 1029311 1029676 1.23E−10 −32.81228879 Hypo-methylatedPCa|NT DMRs chr4 1032712 1035418 1.27E−05 −41.11038961 Hypo-methylatedPCa|NT DMRs chr4 1044864 1049270 1.10E−07 −39.62981366 Hypo-methylatedPCa|NT DMRs chr4 1049394 1049923 1.67E−07 46.01360544 Hyper-methylatedPCa|NT DMRs chr4 1050670 1053023 3.13E−06 −35.13854167 Hypo-methylatedPCa|NT DMRs chr4 1219786 1220184 6.84E−06 −20.43697479 Hypo-methylatedPCa|NT DMRs chr4 1221838 1222191 0.001015461 25.77380952Hyper-methylated PCa|NT DMRs chr4 1288917 1289089 0.00037731728.31785714 Hyper-methylated PCa|NT DMRs chr4 1398732 1399206 6.67E−0720.03513957 Hyper-methylated PCa|NT DMRs chr4 1399634 1399999 6.17E−0720.23904762 Hyper-methylated PCa|NT DMRs chr4 1411454 14135940.005685503 −22.30793651 Hypo-methylated PCa|NT DMRs chr4 14196221419973 0.001083007 −26.79285714 Hypo-methylated PCa|NT DMRs chr41490858 1491097 1.16E−05 −27.80498866 Hypo-methylated PCa|NT DMRs chr41555825 1557487 1.07E−05 −26.10535714 Hypo-methylated PCa|NT DMRs chr41642065 1642543 0.000199784 −31.33406593 Hypo-methylated PCa|NT DMRschr4 1720110 1720849 0.00017871  −38.9547619 Hypo-methylated PCa|NT DMRschr4 1724680 1726858 0.007347803 29.72619048 Hyper-methylated PCa|NTDMRs chr4 1748760 1749266 7.74E−06 −27.23388278 Hypo-methylated PCa|NTDMRs chr4 1753484 1755408 0.001805038 27.78497024 Hyper-methylatedPCa|NT DMRs chr4 1761441 1761940 0.006225823 29.85714286Hyper-methylated PCa|NT DMRs chr4 1762383 1763101 0.002217636−24.14711779 Hypo-methylated PCa|NT DMRs chr4 2059259 20603590.005925694 24.14384921 Hyper-methylated PCa|NT DMRs chr4 20660032068267 1.96E−08 −30.76893939 Hypo-methylated PCa|NT DMRs chr4 24604072460490 0.001969641 −42.95238095 Hypo-methylated PCa|NT DMRs chr42813250 2814969 0.00309961  32.30896359 Hyper-methylated PCa|NT DMRschr4 3042816 3043909 2.82E−10 28.96311858 Hyper-methylated PCa|NT DMRschr4 3081508 3082118 0.005968871 36.65238095 Hyper-methylated PCa|NTDMRs chr4 3322523 3322749 1.97E−05 −26.15952381 Hypo-methylated PCa|NTDMRs chr4 3374739 3375210 0.00187042  35.19047619 Hyper-methylatedPCa|NT DMRs chr4 3461141 3463747 0.00068166  −41.06785714Hypo-methylated PCa|NT DMRs chr4 3472262 3472432 6.42E−05 −48.11904762Hypo-methylated PCa|NT DMRs chr4 3485298 3485482 1.02E−06 24.41478697Hyper-methylated PCa|NT DMRs chr4 3485917 3486308 3.24E−10 −40.02873563Hypo-methylated PCa|NT DMRs chr4 3516421 3516501 0.002097193 33.08979592Hyper-methylated PCa|NT DMRs chr4 3572867 3574998 0.009214933−22.77310924 Hypo-methylated PCa|NT DMRs chr4 3615818 3616211 8.17E−05−36.22294372 Hypo-methylated PCa|NT DMRs chr4 3703042 37032910.005438982 −24.41761905 Hypo-methylated PCa|NT DMRs chr4 37319583732297 0.001969641 −37.72222222 Hypo-methylated PCa|NT DMRs chr43773821 3774409 0.008581782 −21.32142857 Hypo-methylated PCa|NT DMRschr4 3829455 3829864 1.97E−05 −40.09285714 Hypo-methylated PCa|NT DMRschr4 3866527 3866708 0.003622801 −26.42460317 Hypo-methylated PCa|NTDMRs chr4 3873093 3873135 0.00023371  31.27142857 Hyper-methylatedPCa|NT DMRs chr4 3881315 3881658 1.67E−05 21.23809524 Hyper-methylatedPCa|NT DMRs chr4 3947643 3947729 0.000205174 −55.10714286Hypo-methylated PCa|NT DMRs chr4 4149554 4162367 0.003871035−32.16011905 Hypo-methylated PCa|NT DMRs chr4 4167004 41688110.002111644 −30.37875458 Hypo-methylated PCa|NT DMRs chr4 41776724202128 2.38E−05 −23.69738095 Hypo-methylated PCa|NT DMRs chr4 43379764341205 1.97E−05 −32.82666667 Hypo-methylated PCa|NT DMRs chr4 45089914509381 6.42E−05 −63.63492063 Hypo-methylated PCa|NT DMRs chr4 47320034732140 0.005968871 −23.0047619 Hypo-methylated PCa|NT DMRs chr4 47652034765535 1.76E−05 34.97767857 Hyper-methylated PCa|NT DMRs chr4 48596744859847 5.84E−05 43.86111111 Hyper-methylated PCa|NT DMRs chr4 58419925842256 0.000967268 −27.31746032 Hypo-methylated PCa|NT DMRs chr45867725 5868199 0.001789867 21.12962963 Hyper-methylated PCa|NT DMRschr4 5872535 5872659 0.005513661 28.11309524 Hyper-methylated PCa|NTDMRs chr4 5873074 5879341 0.002097193 −27.46938776 Hypo-methylatedPCa|NT DMRs chr4 5892244 5892706 0.000487056 21.31792717Hyper-methylated PCa|NT DMRs chr4 5899432 5907689 0.00449535 −21.55438596 Hypo-methylated PCa|NT DMRs chr4 5930354 5957181 1.28E−08−26.77085714 Hypo-methylated PCa|NT DMRs chr4 5990228 5997337 4.45E−08−27.90634921 Hypo-methylated PCa|NT DMRs chr4 6025011 60263250.000117699 −22.13246753 Hypo-methylated PCa|NT DMRs chr4 63107166314451 6.71E−12 27.86571429 Hyper-methylated PCa|NT DMRs chr4 63818156382787 0.001181579 36.55102041 Hyper-methylated PCa|NT DMRs chr46390691 6392474 2.41E−05 20.48271605 Hyper-methylated PCa|NT DMRs chr46578407 6578819 0.005513661 −32.48809524 Hypo-methylated PCa|NT DMRschr4 6659273 6660594 6.20E−09 35.41931217 Hyper-methylated PCa|NT DMRschr4 6679681 6679830 0.005968871 35.7047619 Hyper-methylated PCa|NT DMRschr4 6694506 6696428 5.42E−05 40.65277778 Hyper-methylated PCa|NT DMRschr4 6883830 6883872 0.004095673 −21.6 Hypo-methylated PCa|NT DMRs chr46891128 6894158 5.84E−05 23.74141414 Hyper-methylated PCa|NT DMRs chr46939615 6940777 0.000589422 25.93859649 Hyper-methylated PCa|NT DMRschr4 7151787 7152611 9.62E−06 −35.4537037 Hypo-methylated PCa|NT DMRschr4 7185889 7193971 0.008234951 −25.27285714 Hypo-methylated PCa|NTDMRs chr4 7297084 7298954 0.000167577 −37.04613095 Hypo-methylatedPCa|NT DMRs chr4 7306667 7308011 7.95E−05 −25.05860806 Hypo-methylatedPCa|NT DMRs chr4 7328211 7334272 5.34E−10 −23.71273533 Hypo-methylatedPCa|NT DMRs chr4 7336839 7337587 0.002879175 −23.08683473Hypo-methylated PCa|NT DMRs chr4 7363202 7370060 4.14E−05 −34.61349206Hypo-methylated PCa|NT DMRs chr4 7394782 7401877 1.22E−05 −26.90785714Hypo-methylated PCa|NT DMRs chr4 7462714 7463938 0.003391914−29.11851852 Hypo-methylated PCa|NT DMRs chr4 7512128 75124510.000197903 −22.3952381 Hypo-methylated PCa|NT DMRs chr4 7520455 75208992.01E−07 −48.115 Hypo-methylated PCa|NT DMRs chr4 7560377 75669639.22E−08 −30.11704261 Hypo-methylated PCa|NT DMRs chr4 7595386 76040010.001391421 −21.03582766 Hypo-methylated PCa|NT DMRs chr4 76323307634423 8.36E−06 −41.17989418 Hypo-methylated PCa|NT DMRs chr4 76932917699047 3.13E−07 −31.19603175 Hypo-methylated PCa|NT DMRs chr4 78297697829989 0.00064571  38.63673469 Hyper-methylated PCa|NT DMRs chr47958232 7958475 0.005968871 21.24095238 Hyper-methylated PCa|NT DMRschr4 8184991 8185183 0.001969641 −65.86666667 Hypo-methylated PCa|NTDMRs chr4 8191543 8193601 2.57E−05 35.57352941 Hyper-methylated PCa|NTDMRs chr4 8201515 8204391 6.48E−12 41.05639589 Hyper-methylated PCa|NTDMRs chr4 8216793 8216969 0.000974795 −55.5 Hypo-methylated PCa|NT DMRschr4 8228509 8229648 8.39E−05 41.0156746 Hyper-methylated PCa|NT DMRschr4 8261808 8262851 0.002562638 −26.54761905 Hypo-methylated PCa|NTDMRs chr4 8263587 8266746 8.96E−05 42.93174603 Hyper-methylated PCa|NTDMRs chr4 8271056 8271692 8.43E−07 25.18376068 Hyper-methylated PCa|NTDMRs chr4 8274761 8276039 0.005835969 26.23396825 Hyper-methylatedPCa|NT DMRs chr4 8429102 8429459 0.008345196 −43.4875 Hypo-methylatedPCa|NT DMRs chr4 8453854 8468108 2.79E−05 −20.88919414 Hypo-methylatedPCa|NT DMRs chr4 9539104 9679680 1.27E−10 −36.01693122 Hypo-methylatedPCa|NT DMRs chr4 9693765 9701202 0.00179283  −30.25297619Hypo-methylated PCa|NT DMRs chr4 9705424 9705454 0.005968871−22.53333333 Hypo-methylated PCa|NT DMRs chr4 9733545 9780270 1.36E−08−28.18826945 Hypo-methylated PCa|NT DMRs chr4 9784902 9916437 4.90E−08−32.93290043 Hypo-methylated PCa|NT DMRs chr4 10035430 100356090.005968871 −35.48571429 Hypo-methylated PCa|NT DMRs chr4 1011681010117450 0.000556158 26.3847619 Hyper-methylated PCa|NT DMRs chr410256054 10385440 6.69E−05 −29.14619048 Hypo-methylated PCa|NT DMRs chr411370382 11370691 1.67E−08 30.99487179 Hyper-methylated PCa|NT DMRs chr411558925 11652784 0.003007728 −30.43150183 Hypo-methylated PCa|NT DMRschr4 12538726 12688866 3.05E−06 −32.96263736 Hypo-methylated PCa|NT DMRschr4 12765196 12785349 0.000117699 −24.64502165 Hypo-methylated PCa|NTDMRs chr4 13691364 14512872 1.10E−19 −29.89767316 Hypo-methylated PCa|NTDMRs chr4 16229075 16240731 0.006195268 35.44480519 Hyper-methylatedPCa|NT DMRs chr4 16322938 16386559 6.42E−05 −30.68148148 Hypo-methylatedPCa|NT DMRs chr4 17439111 17463098 0.001969641 −29.5952381Hypo-methylated PCa|NT DMRs chr4 17783241 17783692 1.02E−05 25.68419048Hyper-methylated PCa|NT DMRs chr4 20256532 20256793 6.90E−08 29.06207483Hyper-methylated PCa|NT DMRs chr4 24374606 24462075 5.78E−09−31.72704762 Hypo-methylated PCa|NT DMRs chr4 24800957 24801882 5.15E−1537.06678424 Hyper-methylated PCa|NT DMRs chr4 24918971 249190560.002826041 30.17006803 Hyper-methylated PCa|NT DMRs chr4 2531522025315306 6.42E−05 −20.0952381 Hypo-methylated PCa|NT DMRs chr4 2584531625862708 0.001428615 23.99107143 Hyper-methylated PCa|NT DMRs chr425880852 25894696 0.00064571  −28.13945578 Hypo-methylated PCa|NT DMRschr4 26222965 26228960 0.003587573 −24.95454545 Hypo-methylated PCa|NTDMRs chr4 26275399 26277170 2.05E−05 39.38831169 Hyper-methylated PCa|NTDMRs chr4 26492350 26492489 0.008482405 −30.2 Hypo-methylated PCa|NTDMRs chr4 27517943 27815111 8.47E−09 −25.84334975 Hypo-methylated PCa|NTDMRs chr4 28977366 29260233 1.60E−11 −26.73258145 Hypo-methylated PCa|NTDMRs chr4 29370807 29544767 1.92E−05 −27.37170868 Hypo-methylated PCa|NTDMRs chr4 29705132 29816256 0.000117738 −30.36825397 Hypo-methylatedPCa|NT DMRs chr4 32417159 32681598 1.23E−14 −31.82037471 Hypo-methylatedPCa|NT DMRs chr4 32765622 33252003 4.35E−10 −31.26654457 Hypo-methylatedPCa|NT DMRs chr4 35081335 35132653 9.98E−10 −30.38857143 Hypo-methylatedPCa|NT DMRs chr4 37409388 37430650 0.001969641 −22.70714286Hypo-methylated PCa|NT DMRs chr4 37456149 37536784 6.11E−05 −25.58536155Hypo-methylated PCa|NT DMRs chr4 38138915 38139074 0.00064571 21.77006803 Hyper-methylated PCa|NT DMRs chr4 39483130 394831950.001969641 38.71768707 Hyper-methylated PCa|NT DMRs chr4 4051682340518046 0.000392715 −35.68619048 Hypo-methylated PCa|NT DMRs chr440564371 40564644 0.002437742 31.29153439 Hyper-methylated PCa|NT DMRschr4 41258790 41259098 5.11E−13 29.49385965 Hyper-methylated PCa|NT DMRschr4 41634825 41634912 0.005968871 43.08571429 Hyper-methylated PCa|NTDMRs chr4 41785626 41790072 0.000226106 −22.67765568 Hypo-methylatedPCa|NT DMRs chr4 43062921 43171463 0.000118733 −29.75661376Hypo-methylated PCa|NT DMRs chr4 46481587 46701221 1.42E−05 −36.74659864Hypo-methylated PCa|NT DMRs chr4 46726479 46726517 0.00026093624.14285714 Hyper-methylated PCa|NT DMRs chr4 46768438 46833223 1.72E−11−23.9175 Hypo-methylated PCa|NT DMRs chr4 46853075 46956338 0.00064571 −38.8 Hypo-methylated PCa|NT DMRs chr4 47222577 47387862 1.75E−06−30.41322751 Hypo-methylated PCa|NT DMRs chr4 48946604 489879660.002400984 26.83174603 Hyper-methylated PCa|NT DMRs chr4 5306009953156841 6.42E−05 −39.47883598 Hypo-methylated PCa|NT DMRs chr4 5370845553714838 0.00064571  −43.42176871 Hypo-methylated PCa|NT DMRs chr454967655 54976202 4.10E−28 36.93661376 Hyper-methylated PCa|NT DMRs chr455015540 55035219 0.000744739 26.81180952 Hyper-methylated PCa|NT DMRschr4 55092628 55093783 6.30E−14 24.46436012 Hyper-methylated PCa|NT DMRschr4 56023416 56023965 0.004505524 24.05882353 Hyper-methylated PCa|NTDMRs chr4 56552514 56574020 6.42E−05 −32.2989418 Hypo-methylated PCa|NTDMRs chr4 56799018 56799469 0.001969641 −26.3984127 Hypo-methylatedPCa|NT DMRs chr4 56964950 56965146 0.00064571  −29.01632653Hypo-methylated PCa|NT DMRs chr4 57594501 57595240 0.005968871−38.73809524 Hypo-methylated PCa|NT DMRs chr4 57603960 576087920.001969641 −54.53333333 Hypo-methylated PCa|NT DMRs chr4 5816658158188744 6.42E−05 −37.15502646 Hypo-methylated PCa|NT DMRs chr4 5859616359038524 1.39E−12 −31.19580499 Hypo-methylated PCa|NT DMRs chr4 5922706160313531 1.05E−29 −29.63496473 Hypo-methylated PCa|NT DMRs chr4 6040593160834746 5.90E−07 −28.43638095 Hypo-methylated PCa|NT DMRs chr4 6222403762253365 0.001969641 −30.22777778 Hypo-methylated PCa|NT DMRs chr462527830 62641591 5.87E−05 −30.25863095 Hypo-methylated PCa|NT DMRs chr463203786 63675452 1.46E−14 −34.23105159 Hypo-methylated PCa|NT DMRs chr463721604 64214752 1.47E−15 −34.50452771 Hypo-methylated PCa|NT DMRs chr464294514 64899391 2.90E−13 −28.92775041 Hypo-methylated PCa|NT DMRs chr464903156 64904679 1.42E−05 −28.18333333 Hypo-methylated PCa|NT DMRs chr466027772 66060053 0.003871035 −21.87083333 Hypo-methylated PCa|NT DMRschr4 67076764 67237811 0.000117507 −32.46753247 Hypo-methylated PCa|NTDMRs chr4 67575557 67786456 1.49E−09 −29.11773399 Hypo-methylated PCa|NTDMRs chr4 68141285 68152698 1.69E−05 −32.23428571 Hypo-methylated PCa|NTDMRs chr4 71517294 71517351 0.005968871 −39.82857143 Hypo-methylatedPCa|NT DMRs chr4 71703513 71703671 0.005968871 −36.62857143Hypo-methylated PCa|NT DMRs chr4 74470061 74470116 0.001181579−39.5170068 Hypo-methylated PCa|NT DMRs chr4 74735344 747355440.000826653 24.62202381 Hyper-methylated PCa|NT DMRs chr4 7997115079971392 6.42E−05 −66.02116402 Hypo-methylated PCa|NT DMRs chr4 8112834481128545 0.001391421 20.66233766 Hyper-methylated PCa|NT DMRs chr481188030 81189752 2.66E−09 25.02551893 Hyper-methylated PCa|NT DMRs chr481222832 81229128 0.002097193 −42.65306122 Hypo-methylated PCa|NT DMRschr4 81257352 81257875 0.007560755 21.65079365 Hyper-methylated PCa|NTDMRs chr4 84029495 84030975 0.006207271 44.14285714 Hyper-methylatedPCa|NT DMRs chr4 85246157 85246262 0.001344447 35.33928571Hyper-methylated PCa|NT DMRs chr4 86049074 86276626 0.002529619−33.2996337 Hypo-methylated PCa|NT DMRs chr4 87770576 877931060.00641359  −34.06984127 Hypo-methylated PCa|NT DMRs chr4 8781445987814664 0.007959104 −28.55102041 Hypo-methylated PCa|NT DMRs chr490600720 90600871 0.005968871 40.15238095 Hyper-methylated PCa|NT DMRschr4 93397456 94616247 6.45E−31 −31.09215969 Hypo-methylated PCa|NT DMRschr4 94750894 94756007 1.66E−05 30.42095238 Hyper-methylated PCa|NT DMRschr4 96468588 96469265 1.92E−05 21.86904762 Hyper-methylated PCa|NT DMRschr4 99416600 99416658 0.00068166  −24.16369048 Hypo-methylated PCa|NTDMRs chr4 99997615 100008409 3.39E−06 −34.13779762 Hypo-methylatedPCa|NT DMRs chr4 100575453 100603348 0.000125197 −27.34065934Hypo-methylated PCa|NT DMRs chr4 104458935 104524599 0.005968871−33.07428571 Hypo-methylated PCa|NT DMRs chr4 104719128 1048321213.82E−07 −34.40113379 Hypo-methylated PCa|NT DMRs chr4 105237730105327614 0.001969641 −30.35396825 Hypo-methylated PCa|NT DMRs chr4107340712 107393166 0.00064571  −37.02380952 Hypo-methylated PCa|NT DMRschr4 107958117 107958168 0.00064571  25.77891156 Hyper-methylated PCa|NTDMRs chr4 107982224 108047704 4.16E−07 −24.87559524 Hypo-methylatedPCa|NT DMRs chr4 108912031 108928173 0.002437742 −36.66402116Hypo-methylated PCa|NT DMRs chr4 110480731 110481098 8.63E−0521.31819728 Hyper-methylated PCa|NT DMRs chr4 111540025 1115417641.96E−05 20.82571429 Hyper-methylated PCa|NT DMRs chr4 111562359111562635 8.31E−07 25.76466165 Hyper-methylated PCa|NT DMRs chr4113432375 113436136 0.000216379 20.39100529 Hyper-methylated PCa|NT DMRschr4 113630671 113650639 2.01E−07 −26.40333333 Hypo-methylated PCa|NTDMRs chr4 114823634 114823795 0.005968871 −32.71428571 Hypo-methylatedPCa|NT DMRs chr4 115580142 116035083 9.00E−07 −30.6375 Hypo-methylatedPCa|NT DMRs chr4 120596211 120875811 4.62E−05 −23.43015873Hypo-methylated PCa|NT DMRs chr4 123505088 123505240 0.005968871−27.94285714 Hypo-methylated PCa|NT DMRs chr4 123747810 1237478984.85E−08 22.07142857 Hyper-methylated PCa|NT DMRs chr4 126239191126539569 1.56E−09 −31.06453202 Hypo-methylated PCa|NT DMRs chr4126692918 127411465 1.56E−32 −32.94203297 Hypo-methylated PCa|NT DMRschr4 127591407 127794613 0.000260936 −33.26857143 Hypo-methylated PCa|NTDMRs chr4 127795836 127849482 6.17E−06 −28.40357143 Hypo-methylatedPCa|NT DMRs chr4 128239783 128502727 1.29E−07 −27.00226757Hypo-methylated PCa|NT DMRs chr4 129511106 129512806 0.001789867−28.7989418 Hypo-methylated PCa|NT DMRs chr4 130053051 1306239860.000406444 −22.76326531 Hypo-methylated PCa|NT DMRs chr4 131416828132385910 5.11E−23 −26.28225108 Hypo-methylated PCa|NT DMRs chr4132898758 132959575 3.46E−07 −24.48690476 Hypo-methylated PCa|NT DMRschr4 133107255 133488006 2.82E−07 −25.67281746 Hypo-methylated PCa|NTDMRs chr4 133730649 134029195 1.10E−05 −32.97172619 Hypo-methylatedPCa|NT DMRs chr4 134301057 134306479 0.003622801 −32.23809524Hypo-methylated PCa|NT DMRs chr4 135873891 135919809 2.86E−05−25.12637363 Hypo-methylated PCa|NT DMRs chr4 136327930 1369295935.45E−13 −23.97537994 Hypo-methylated PCa|NT DMRs chr4 137098530137316687 1.91E−18 −25.55631141 Hypo-methylated PCa|NT DMRs chr4137416378 137733900 5.48E−17 −25.82677596 Hypo-methylated PCa|NT DMRschr4 137790035 137850577 2.86E−05 −32.6040293 Hypo-methylated PCa|NTDMRs chr4 139831807 139833697 1.97E−05 −39.67952381 Hypo-methylatedPCa|NT DMRs chr4 139964244 139964408 0.001969641 −53.24206349Hypo-methylated PCa|NT DMRs chr4 140187743 140188008 0.00409567349.35555556 Hyper-methylated PCa|NT DMRs chr4 140554198 1405552191.88E−07 −34.77747748 Hypo-methylated PCa|NT DMRs chr4 140656525140686025 5.84E−05 28.68869048 Hyper-methylated PCa|NT DMRs chr4141489765 141489975 0.005968871 26.17099567 Hyper-methylated PCa|NT DMRschr4 143992360 144068518 9.23E−05 −20.30112045 Hypo-methylated PCa|NTDMRs chr4 144865812 145566787 7.88E−11 −22.33043758 Hypo-methylatedPCa|NT DMRs chr4 145585398 145605621 1.21E−07 −32.4375 Hypo-methylatedPCa|NT DMRs chr4 146830918 146831059 0.005968871 −58.05714286Hypo-methylated PCa|NT DMRs chr4 147164826 147165045 0.00596887125.94285714 Hyper-methylated PCa|NT DMRs chr4 147576548 1475766147.19E−05 24.01190476 Hyper-methylated PCa|NT DMRs chr4 148963047148970731 0.00064571  −41.92176871 Hypo-methylated PCa|NT DMRs chr4152782627 152804741 0.000836132 −20.73333333 Hypo-methylated PCa|NT DMRschr4 153600942 153601467 5.28E−09 23.99434524 Hyper-methylated PCa|NTDMRs chr4 154386835 154386925 6.42E−05 35.53968254 Hyper-methylatedPCa|NT DMRs chr4 155444642 155444910 5.84E−05 −35.24404762Hypo-methylated PCa|NT DMRs chr4 156933349 157120030 5.47E−10−38.28897243 Hypo-methylated PCa|NT DMRs chr4 158175644 1585575792.36E−16 −33.3627794 Hypo-methylated PCa|NT DMRs chr4 158740298158914185 0.000543976 −27.44047619 Hypo-methylated PCa|NT DMRs chr4162440444 162699172 4.22E−19 −29.30041051 Hypo-methylated PCa|NT DMRschr4 162898581 162918857 6.42E−05 −34.8978836 Hypo-methylated PCa|NTDMRs chr4 163442605 163594802 0.00023371  −36.06380952 Hypo-methylatedPCa|NT DMRs chr4 164097383 164246589 3.44E−06 −40.11041667Hypo-methylated PCa|NT DMRs chr4 164264854 164264949 2.39E−0522.14880952 Hyper-methylated PCa|NT DMRs chr4 167724679 1678828612.73E−06 −26.62857143 Hypo-methylated PCa|NT DMRs chr4 169991576169991815 0.005968871 −55.43809524 Hypo-methylated PCa|NT DMRs chr4170695756 170696193 0.000206041 30.95846561 Hyper-methylated PCa|NT DMRschr4 170698920 170708508 2.42E−05 −24.39863946 Hypo-methylated PCa|NTDMRs chr4 171630877 172251746 6.08E−36 −29.58325775 Hypo-methylatedPCa|NT DMRs chr4 172332382 172637033 6.16E−06 −31.00092166Hypo-methylated PCa|NT DMRs chr4 177310888 177546393 4.30E−08−28.99370748 Hypo-methylated PCa|NT DMRs chr4 177913924 1780589181.57E−07 −34.27967033 Hypo-methylated PCa|NT DMRs chr4 178302966178322402 5.19E−07 −35.1003663 Hypo-methylated PCa|NT DMRs chr4180312144 180978557 4.85E−13 −32.65024295 Hypo-methylated PCa|NT DMRschr4 182454200 182481924 0.005968871 −28.74285714 Hypo-methylated PCa|NTDMRs chr4 183061633 183064642 1.16E−12 29.45541872 Hyper-methylatedPCa|NT DMRs chr4 183386534 183386716 0.005968871 −52.6 Hypo-methylatedPCa|NT DMRs chr4 183728044 183729468 3.63E−07 25.4262585Hyper-methylated PCa|NT DMRs chr4 183749598 183749860 2.03E−06−29.11714286 Hypo-methylated PCa|NT DMRs chr4 184277792 1842980171.67E−07 −30.06961451 Hypo-methylated PCa|NT DMRs chr4 184643001184643067 0.004095673 34.30952381 Hyper-methylated PCa|NT DMRs chr4184675775 184681351 0.007959104 −40.31020408 Hypo-methylated PCa|NT DMRschr4 184762268 184764025 0.000974795 −37.76428571 Hypo-methylated PCa|NTDMRs chr4 184931420 184941019 0.003122338 −28.71626984 Hypo-methylatedPCa|NT DMRs chr4 185110930 185138997 0.000783791 −29.43285714Hypo-methylated PCa|NT DMRs chr4 185323926 185331194 0.00423697439.52428571 Hyper-methylated PCa|NT DMRs chr4 185936960 1859375273.46E−07 32.10337302 Hyper-methylated PCa|NT DMRs chr4 186559938186573655 2.72E−06 38.22196621 Hyper-methylated PCa|NT DMRs chr4186573817 186573873 0.005968871 −40.74761905 Hypo-methylated PCa|NT DMRschr4 186954181 186961778 5.22E−05 −45.33605442 Hypo-methylated PCa|NTDMRs chr4 187218545 187218676 0.005594179 −21.64172336 Hypo-methylatedPCa|NT DMRs chr4 187219383 187219649 0.001836557 25.61538462Hyper-methylated PCa|NT DMRs chr4 187572821 187573086 2.61E−07−49.39047619 Hypo-methylated PCa|NT DMRs chr4 188897841 1888982510.005968871 −41.69142857 Hypo-methylated PCa|NT DMRs chr4 188953227188953415 0.00064571  39.06122449 Hyper-methylated PCa|NT DMRs chr4189039289 189043369 0.001850915 −29.35357143 Hypo-methylated PCa|NT DMRschr4 189102844 189103423 0.00064571  −61.36054422 Hypo-methylated PCa|NTDMRs chr4 189204176 189204454 9.33E−05 21.47 Hyper-methylated PCa|NTDMRs chr4 189257667 189259026 0.000481535 −31.10687831 Hypo-methylatedPCa|NT DMRs chr4 189390720 189433429 1.42E−05 −35.42006803Hypo-methylated PCa|NT DMRs chr5 36644 49847 0.005968871 −38.56571429Hypo-methylated PCa|NT DMRs chr5 54484 54571 0.000205174 37.51488095Hyper-methylated PCa|NT DMRs chr5 173045 173196 0.005513661 27.625Hyper-methylated PCa|NT DMRs chr5 191676 192133 2.77E−06 36.03267196Hyper-methylated PCa|NT DMRs chr5 322366 323864 9.10E−12 26.61380145Hyper-methylated PCa|NT DMRs chr5 346708 346994 0.000339757 42.35497835Hyper-methylated PCa|NT DMRs chr5 429311 429595 0.002373155 26.23386243Hyper-methylated PCa|NT DMRs chr5 484994 485992 1.52E−07 −33.01020408Hypo-methylated PCa|NT DMRs chr5 486402 486528 0.000354065 25.49206349Hyper-methylated PCa|NT DMRs chr5 491998 493316 0.000184589 −21.4272578Hypo-methylated PCa|NT DMRs chr5 496299 496580 0.000481535 −32.9015873Hypo-methylated PCa|NT DMRs chr5 504872 506563 0.000775062 −26.11564626Hypo-methylated PCa|NT DMRs chr5 510035 513353 0.009924186 −20.37142857Hypo-methylated PCa|NT DMRs chr5 524990 525799 0.004047992 20.59013605Hyper-methylated PCa|NT DMRs chr5 528034 531433 4.46E−17 21.77670807Hyper-methylated PCa|NT DMRs chr5 540534 541926 0.00010546  −27.95873016Hypo-methylated PCa|NT DMRs chr5 544499 544586 0.005968871 23.34285714Hyper-methylated PCa|NT DMRs chr5 570255 574375 7.37E−05 −21.99482402Hypo-methylated PCa|NT DMRs chr5 672237 673043 0.000911204 −30.33154762Hypo-methylated PCa|NT DMRs chr5 759101 759173 0.001969641 −45.14285714Hypo-methylated PCa|NT DMRs chr5 891730 891887 0.00064571  28.65306122Hyper-methylated PCa|NT DMRs chr5 931118 931365 0.000481535 −29.87301587Hypo-methylated PCa|NT DMRs chr5 958837 960204 9.50E−05 −46.33643892Hypo-methylated PCa|NT DMRs chr5 982032 982752 0.003764982 −25.56904762Hypo-methylated PCa|NT DMRs chr5 1101971 1102748 0.003034084 25.38027211Hyper-methylated PCa|NT DMRs chr5 1106174 1109475 6.30E−16 34.92054016Hyper-methylated PCa|NT DMRs chr5 1130994 1131377 6.69E−05 −21.97714286Hypo-methylated PCa|NT DMRs chr5 1161973 1162279 6.42E−05 −41.11111111Hypo-methylated PCa|NT DMRs chr5 1201147 1202000 1.15E−06 −29.14115004Hypo-methylated PCa|NT DMRs chr5 1245835 1245903 0.001969641−28.78571429 Hypo-methylated PCa|NT DMRs chr5 1282489 1282797 6.34E−06−25.92857143 Hypo-methylated PCa|NT DMRs chr5 1408867 1409169 2.05E−0536.5974026 Hyper-methylated PCa|NT DMRs chr5 1493248 1497619 0.00182109621.92431973 Hyper-methylated PCa|NT DMRs chr5 1593020 1594436 2.69E−0623.16300366 Hyper-methylated PCa|NT DMRs chr5 1617871 16200460.000226073 20.28428571 Hyper-methylated PCa|NT DMRs chr5 16425281643655 8.96E−05 −24.6452381 Hypo-methylated PCa|NT DMRs chr5 17678361768211 0.002770271 −22.2967033 Hypo-methylated PCa|NT DMRs chr5 17706781772639 6.21E−07 −41.0789916 Hypo-methylated PCa|NT DMRs chr5 17871841787751 0.003871035 −34.24702381 Hypo-methylated PCa|NT DMRs chr51800475 1800685 5.02E−05 21.31092437 Hyper-methylated PCa|NT DMRs chr51841249 1841681 1.52E−07 39.65884354 Hyper-methylated PCa|NT DMRs chr51887890 1888331 1.33E−06 24.66666667 Hyper-methylated PCa|NT DMRs chr51912091 1914239 4.08E−06 −23.68005952 Hypo-methylated PCa|NT DMRs chr51947200 1950439 4.18E−07 −33.49062049 Hypo-methylated PCa|NT DMRs chr51952403 1953067 6.94E−06 32.30539683 Hyper-methylated PCa|NT DMRs chr52007414 2008029 1.65E−08 −33.48467262 Hypo-methylated PCa|NT DMRs chr52627370 2635841 0.000554289 −29.82301587 Hypo-methylated PCa|NT DMRschr5 2646033 2657115 0.004149771 −29.01978022 Hypo-methylated PCa|NTDMRs chr5 2737144 2739365 9.98E−10 30.8673774 Hyper-methylated PCa|NTDMRs chr5 5320280 5320485 0.00064571  −45.55102041 Hypo-methylatedPCa|NT DMRs chr5 5688533 5688867 0.00068166  28.1452381 Hyper-methylatedPCa|NT DMRs chr5 5887486 5954559 9.84E−07 −28.18272109 Hypo-methylatedPCa|NT DMRs chr5 6583091 6583897 3.60E−15 30.54106167 Hyper-methylatedPCa|NT DMRs chr5 6999237 7002383 0.005968871 −27.66190476Hypo-methylated PCa|NT DMRs chr5 7873542 7873602 0.004057568 23.42857143Hyper-methylated PCa|NT DMRs chr5 7891828 8429773 1.26E−18 −29.71930855Hypo-methylated PCa|NT DMRs chr5 8822315 8839953 0.001969641−42.53571429 Hypo-methylated PCa|NT DMRs chr5 9090845 9328923 2.49E−08−27.57619048 Hypo-methylated PCa|NT DMRs chr5 9546424 9546840 6.10E−0828.60057143 Hyper-methylated PCa|NT DMRs chr5 9606704 10065719 1.08E−12−28.94210526 Hypo-methylated PCa|NT DMRs chr5 10080596 100833480.000111427 −29.24285714 Hypo-methylated PCa|NT DMRs chr5 1046691010467001 0.005968871 50.00952381 Hyper-methylated PCa|NT DMRs chr510519079 10519314 0.005968871 −34.45714286 Hypo-methylated PCa|NT DMRschr5 10561931 10563665 1.74E−06 31.00625 Hyper-methylated PCa|NT DMRschr5 10625692 10632701 0.003391914 27.38624339 Hyper-methylated PCa|NTDMRs chr5 10638145 10650090 1.50E−10 −30.05619048 Hypo-methylated PCa|NTDMRs chr5 10761664 10762290 6.95E−05 30.00952381 Hyper-methylated PCa|NTDMRs chr5 12574955 12590482 0.001969641 −23.98968254 Hypo-methylatedPCa|NT DMRs chr5 12664526 12777965 6.67E−06 −22.53303571 Hypo-methylatedPCa|NT DMRs chr5 12805449 13466472 4.39E−16 −33.2144528 Hypo-methylatedPCa|NT DMRs chr5 13579536 13642747 3.77E−05 −22.21507937 Hypo-methylatedPCa|NT DMRs chr5 14131700 14132687 0.003464153 −22.24242424Hypo-methylated PCa|NT DMRs chr5 16215940 16226414 0.001969641−33.90873016 Hypo-methylated PCa|NT DMRs chr5 16740672 167408200.00064571  37.93877551 Hyper-methylated PCa|NT DMRs chr5 1705307517061084 0.007959104 −38.52789116 Hypo-methylated PCa|NT DMRs chr517218716 17219330 0.000575877 29.7965368 Hyper-methylated PCa|NT DMRschr5 17506966 17620988 0.001775064 −27.71190476 Hypo-methylated PCa|NTDMRs chr5 18113703 18291499 6.42E−05 −34.58201058 Hypo-methylated PCa|NTDMRs chr5 18468601 18701383 5.91E−05 −24.67981859 Hypo-methylated PCa|NTDMRs chr5 18754451 18837250 7.28E−07 −32.2556391 Hypo-methylated PCa|NTDMRs chr5 18902785 19105793 2.27E−11 −35.88246753 Hypo-methylated PCa|NTDMRs chr5 19185189 19360890 3.12E−11 −30.36013289 Hypo-methylated PCa|NTDMRs chr5 19630207 19687332 0.000398029 −29.36263736 Hypo-methylatedPCa|NT DMRs chr5 20693877 21044402 7.31E−05 −28.2755102 Hypo-methylatedPCa|NT DMRs chr5 21876551 21935096 6.42E−05 −34.72698413 Hypo-methylatedPCa|NT DMRs chr5 23179652 23411522 2.52E−13 −33.49488966 Hypo-methylatedPCa|NT DMRs chr5 24318343 24433204 2.38E−07 −29.10497835 Hypo-methylatedPCa|NT DMRs chr5 24706900 25154479 1.28E−12 −36.04371184 Hypo-methylatedPCa|NT DMRs chr5 25190742 25200415 4.05E−15 −25.99439153 Hypo-methylatedPCa|NT DMRs chr5 25710410 26030670 1.56E−18 −33.20130568 Hypo-methylatedPCa|NT DMRs chr5 26145538 26229422 1.23E−07 −33.65833333 Hypo-methylatedPCa|NT DMRs chr5 26324500 26468493 6.33E−13 −31.26825397 Hypo-methylatedPCa|NT DMRs chr5 26704766 27230652 2.88E−25 −37.77136978 Hypo-methylatedPCa|NT DMRs chr5 27267583 27408078 0.000145366 −34.05204082Hypo-methylated PCa|NT DMRs chr5 27493792 27783717 3.09E−13 −26.32439261Hypo-methylated PCa|NT DMRs chr5 28575715 28747075 3.19E−07 −28.87929607Hypo-methylated PCa|NT DMRs chr5 28928178 28928431 3.62E−08 21.83669468Hyper-methylated PCa|NT DMRs chr5 30139519 30169473 0.000377317−32.99107143 Hypo-methylated PCa|NT DMRs chr5 30345913 30346846 2.66E−05−25.69546485 Hypo-methylated PCa|NT DMRs chr5 30935659 31182658 8.01E−11−29.88404762 Hypo-methylated PCa|NT DMRs chr5 31212521 31339254 2.06E−05−36.32823129 Hypo-methylated PCa|NT DMRs chr5 31639750 31640087 8.92E−0630.04004329 Hyper-methylated PCa|NT DMRs chr5 32128621 321286890.00064571  −28.04081633 Hypo-methylated PCa|NT DMRs chr5 3258799532613011 0.000564835 −29.72142857 Hypo-methylated PCa|NT DMRs chr533891748 33892458 1.18E−08 37.00416667 Hyper-methylated PCa|NT DMRs chr537834171 37836849 6.90E−10 22.48412698 Hyper-methylated PCa|NT DMRs chr537838564 37839313 2.73E−05 22.02756892 Hyper-methylated PCa|NT DMRs chr538016960 38017179 0.001969641 −20.28571429 Hypo-methylated PCa|NT DMRschr5 38257858 38258134 5.19E−07 33.73699634 Hyper-methylated PCa|NT DMRschr5 40930560 41204864 2.07E−09 −29.95608466 Hypo-methylated PCa|NT DMRschr5 41520375 41520434 0.004947537 −32.67936508 Hypo-methylated PCa|NTDMRs chr5 42756739 42756905 0.003622801 29.21031746 Hyper-methylatedPCa|NT DMRs chr5 43603430 43604298 1.16E−11 27.46957027 Hyper-methylatedPCa|NT DMRs chr5 43745994 43825042 3.61E−19 −27.48801843 Hypo-methylatedPCa|NT DMRs chr5 44209423 44209492 0.005968871 −33.97142857Hypo-methylated PCa|NT DMRs chr5 44483467 44559127 6.23E−06 −32.41077694Hypo-methylated PCa|NT DMRs chr5 44847360 44862657 0.005968871−41.48571429 Hypo-methylated PCa|NT DMRs chr5 45889683 458911290.003764982 −21.58611111 Hypo-methylated PCa|NT DMRs chr5 4997139549971443 0.005968871 −48.74285714 Hypo-methylated PCa|NT DMRs chr550260158 50264788 5.12E−08 33.44543651 Hyper-methylated PCa|NT DMRs chr550699155 50925915 0.002097193 −38.13605442 Hypo-methylated PCa|NT DMRschr5 51175685 51257655 6.50E−05 −26.44312169 Hypo-methylated PCa|NT DMRschr5 52096913 52097499 0.001451132 −36.37142857 Hypo-methylated PCa|NTDMRs chr5 52778621 52778799 0.003949155 41.11507937 Hyper-methylatedPCa|NT DMRs chr5 53941842 53942290 0.008482405 46.34285714Hyper-methylated PCa|NT DMRs chr5 54530301 54537833 0.003622801−35.33333333 Hypo-methylated PCa|NT DMRs chr5 57859560 57859666 5.83E−05−22.65833333 Hypo-methylated PCa|NT DMRs chr5 58423471 584237260.000468799 47.71428571 Hyper-methylated PCa|NT DMRs chr5 6454894364754400 1.57E−06 −20.90993789 Hypo-methylated PCa|NT DMRs chr5 6646144466504456 2.85E−11 29.43103448 Hyper-methylated PCa|NT DMRs chr5 6748295767483406 0.000377317 −29.425 Hypo-methylated PCa|NT DMRs chr5 6833929868363946 0.005339316 −22.95442177 Hypo-methylated PCa|NT DMRs chr570979930 71015616 0.009788405 23.55442177 Hyper-methylated PCa|NT DMRschr5 71234676 71235006 0.005968871 −45.28285714 Hypo-methylated PCa|NTDMRs chr5 72731939 72732636 6.92E−15 27.50103896 Hyper-methylated PCa|NTDMRs chr5 72740460 72740771 0.000111427 29.60238095 Hyper-methylatedPCa|NT DMRs chr5 74162557 74162881 0.000254585 29.04166667Hyper-methylated PCa|NT DMRs chr5 75013592 75013683 0.004095673−22.10714286 Hypo-methylated PCa|NT DMRs chr5 75377487 753780640.000199784 27.05488722 Hyper-methylated PCa|NT DMRs chr5 7693344876940450 1.61E−24 22.14285714 Hyper-methylated PCa|NT DMRs chr5 7726841777270020 1.00E−10 26.12254616 Hyper-methylated PCa|NT DMRs chr5 7794329677943461 0.003622801 41.11904762 Hyper-methylated PCa|NT DMRs chr578984891 78985871 2.89E−15 −42.11079932 Hypo-methylated PCa|NT DMRs chr579167786 79169828 0.003949155 −25.10714286 Hypo-methylated PCa|NT DMRschr5 80528526 80528737 0.00641359  −24.14285714 Hypo-methylated PCa|NTDMRs chr5 82155603 82155778 0.00064571  −41.51020408 Hypo-methylatedPCa|NT DMRs chr5 83024021 83642055 1.93E−13 −32.61940035 Hypo-methylatedPCa|NT DMRs chr5 85756620 85865687 2.32E−10 −29.24831933 Hypo-methylatedPCa|NT DMRs chr5 90794947 90795417 0.001181579 −35.24421769Hypo-methylated PCa|NT DMRs chr5 91030006 91244923 4.10E−09 −31.82126984Hypo-methylated PCa|NT DMRs chr5 92346121 92521069 0.005968871−24.07619048 Hypo-methylated PCa|NT DMRs chr5 94955700 949559350.005968871 34.44666667 Hyper-methylated PCa|NT DMRs chr5 9515982695163055 0.003448944 41.57346939 Hyper-methylated PCa|NT DMRs chr595295896 95296042 0.000972067 −29.4047619 Hypo-methylated PCa|NT DMRschr5 98420562 98695197 6.98E−05 −28.56938776 Hypo-methylated PCa|NT DMRschr5 98909608 99401805 3.77E−14 −30.68787062 Hypo-methylated PCa|NT DMRschr5 101373974 101463725 6.42E−05 −34.59470899 Hypo-methylated PCa|NTDMRs chr5 101827404 101941754 5.01E−08 −32.71172161 Hypo-methylatedPCa|NT DMRs chr5 103074137 103100319 0.000117699 −29.67662338Hypo-methylated PCa|NT DMRs chr5 103156025 103285997 1.15E−06−26.89484127 Hypo-methylated PCa|NT DMRs chr5 104269547 1044507700.00064571  −27.0170068 Hypo-methylated PCa|NT DMRs chr5 105554186105582068 4.90E−08 −26.07467532 Hypo-methylated PCa|NT DMRs chr5105954399 106038183 0.000118733 −32.21746032 Hypo-methylated PCa|NT DMRschr5 107778055 107895031 0.000145094 −27.28571429 Hypo-methylated PCa|NTDMRs chr5 109468813 109883511 4.09E−06 −24.74421769 Hypo-methylatedPCa|NT DMRs chr5 110948125 110953963 0.000339627 −29.92420635Hypo-methylated PCa|NT DMRs chr5 111194066 111440748 3.43E−06−37.04017857 Hypo-methylated PCa|NT DMRs chr5 112373361 1123794420.001789867 −26.14021164 Hypo-methylated PCa|NT DMRs chr5 115912116115912302 7.75E−06 21.84033613 Hyper-methylated PCa|NT DMRs chr5121187787 121266661 2.97E−11 −24.61230159 Hypo-methylated PCa|NT DMRschr5 122620950 122621646 4.33E−05 35.88278388 Hyper-methylated PCa|NTDMRs chr5 124079870 124079990 0.00064571  30.84761905 Hyper-methylatedPCa|NT DMRs chr5 125259773 125259951 0.00179283  −28.35595238Hypo-methylated PCa|NT DMRs chr5 125937484 125937691 0.000392715−30.21428571 Hypo-methylated PCa|NT DMRs chr5 126204968 1262050186.20E−05 43.96938776 Hyper-methylated PCa|NT DMRs chr5 129116030129204213 0.00641359  −27.14285714 Hypo-methylated PCa|NT DMRs chr5132602532 132613572 0.00064571  20.40204082 Hyper-methylated PCa|NT DMRschr5 132830468 132830845 0.000974795 −41.42559524 Hypo-methylated PCa|NTDMRs chr5 133264423 133264557 0.008482405 34.31428571 Hyper-methylatedPCa|NT DMRs chr5 133451049 133477329 2.40E−06 21.32251701Hyper-methylated PCa|NT DMRs chr5 133513536 133513690 0.005968871−46.71428571 Hypo-methylated PCa|NT DMRs chr5 133890165 1339052320.001238355 −30.08809524 Hypo-methylated PCa|NT DMRs chr5 134009546134016320 0.003622801 −35.85714286 Hypo-methylated PCa|NT DMRs chr5134713990 134714234 0.005968871 46.62380952 Hyper-methylated PCa|NT DMRschr5 134735440 134735756 0.003871035 31.54702381 Hyper-methylated PCa|NTDMRs chr5 134818134 134823833 0.001583951 27.58095238 Hyper-methylatedPCa|NT DMRs chr5 135415093 135415259 3.32E−06 32.56507937Hyper-methylated PCa|NT DMRs chr5 137225015 137225102 6.94E−0627.58095238 Hyper-methylated PCa|NT DMRs chr5 137794151 1377953066.94E−06 48.03428571 Hyper-methylated PCa|NT DMRs chr5 138849588138852391 0.002654087 32.89115646 Hyper-methylated PCa|NT DMRs chr5138855434 138870698 0.004172333 25.32912088 Hyper-methylated PCa|NT DMRschr5 138923154 138923271 0.00064571  44.50340136 Hyper-methylated PCa|NTDMRs chr5 139026562 139027511 1.42E−05 28.85504762 Hyper-methylatedPCa|NT DMRs chr5 139127989 139128275 0.000632596 28.90606061Hyper-methylated PCa|NT DMRs chr5 139284247 139284813 0.00015320420.28571429 Hyper-methylated PCa|NT DMRs chr5 139303814 1393045708.96E−05 −29.08333333 Hypo-methylated PCa|NT DMRs chr5 139525949139528263 3.38E−07 48.17391304 Hyper-methylated PCa|NT DMRs chr5139532389 139533233 0.005513661 28.66938776 Hyper-methylated PCa|NT DMRschr5 140098496 140099544 5.94E−06 −43.77186147 Hypo-methylated PCa|NTDMRs chr5 140347000 140347544 0.005033773 22.76785714 Hyper-methylatedPCa|NT DMRs chr5 140723450 140723770 0.004422055 21.58095238Hyper-methylated PCa|NT DMRs chr5 140892917 140936423 0.00032859232.02517007 Hyper-methylated PCa|NT DMRs chr5 141062050 1410659160.000133092 36.92202381 Hyper-methylated PCa|NT DMRs chr5 141325409141330954 0.001969641 32.31904762 Hyper-methylated PCa|NT DMRs chr5141337511 141338045 0.00064571  40.27687075 Hyper-methylated PCa|NT DMRschr5 141675101 141675185 0.000392715 28.33809524 Hyper-methylated PCa|NTDMRs chr5 141703419 141703630 0.000205174 43.92857143 Hyper-methylatedPCa|NT DMRs chr5 141737215 141737877 0.000335989 32.86520147Hyper-methylated PCa|NT DMRs chr5 141931182 141931551 5.19E−0735.09340659 Hyper-methylated PCa|NT DMRs chr5 141980430 1419806030.001969641 −51.40634921 Hypo-methylated PCa|NT DMRs chr5 142563071142563232 0.008482405 47.60952381 Hyper-methylated PCa|NT DMRs chr5145099211 145132848 0.001181579 −26.26530612 Hypo-methylated PCa|NT DMRschr5 145214426 145214485 0.00023371  21.44285714 Hyper-methylated PCa|NTDMRs chr5 145235917 145236069 0.002097193 32.66122449 Hyper-methylatedPCa|NT DMRs chr5 146302496 146493322 4.48E−06 −26.44738095Hypo-methylated PCa|NT DMRs chr5 148463858 148505346 0.009069241−36.68398268 Hypo-methylated PCa|NT DMRs chr5 148610935 1486202540.005513661 41.85714286 Hyper-methylated PCa|NT DMRs chr5 148678581148679101 1.12E−06 44.89021164 Hyper-methylated PCa|NT DMRs chr5148762553 148784809 0.005968871 39.57142857 Hyper-methylated PCa|NT DMRschr5 149010096 149010377 0.002097193 −28.23809524 Hypo-methylated PCa|NTDMRs chr5 149020890 149033180 0.001969641 −54.88095238 Hypo-methylatedPCa|NT DMRs chr5 149056968 149067470 0.004350823 40.47619048Hyper-methylated PCa|NT DMRs chr5 149312425 149312649 0.000114675−32.92857143 Hypo-methylated PCa|NT DMRs chr5 149319932 1493241520.004537864 26.81318681 Hyper-methylated PCa|NT DMRs chr5 149495250149495624 0.000339757 27.84199134 Hyper-methylated PCa|NT DMRs chr5149507322 149512117 0.007679542 −20.4984127 Hypo-methylated PCa|NT DMRschr5 149546247 149546970 1.09E−12 27.17352381 Hyper-methylated PCa|NTDMRs chr5 149680272 149682357 7.47E−08 28.3971686 Hyper-methylatedPCa|NT DMRs chr5 149788811 149792331 0.00090274  22.56428571Hyper-methylated PCa|NT DMRs chr5 150226252 150226355 0.00064571 54.37755102 Hyper-methylated PCa|NT DMRs chr5 150381248 1504004617.67E−07 29.93471582 Hyper-methylated PCa|NT DMRs chr5 150461339150480143 0.003921091 39.46493506 Hyper-methylated PCa|NT DMRs chr5150535926 150537241 2.49E−05 34.22811791 Hyper-methylated PCa|NT DMRschr5 150701672 150703337 0.00068166  −22.02083333 Hypo-methylated PCa|NTDMRs chr5 150759836 150775766 0.000652677 −20.83134921 Hypo-methylatedPCa|NT DMRs chr5 151066304 151066713 1.42E−05 36.95918367Hyper-methylated PCa|NT DMRs chr5 151149074 151150352 0.00730501322.89285714 Hyper-methylated PCa|NT DMRs chr5 151205902 1512614950.005685126 −22.72857143 Hypo-methylated PCa|NT DMRs chr5 151355980151540167 0.000118733 −28.80952381 Hypo-methylated PCa|NT DMRs chr5153872888 153873228 4.26E−06 30.43736264 Hyper-methylated PCa|NT DMRschr5 154026679 154027124 1.47E−07 26.29251701 Hyper-methylated PCa|NTDMRs chr5 154318209 154320377 0.007347803 −24.31746032 Hypo-methylatedPCa|NT DMRs chr5 157038194 157058698 0.000117507 −23.5025974Hypo-methylated PCa|NT DMRs chr5 157464019 157464759 7.33E−05−22.34063492 Hypo-methylated PCa|NT DMRs chr5 158478379 1584785941.93E−10 28.34047619 Hyper-methylated PCa|NT DMRs chr5 158523996158526005 3.00E−08 29.16324405 Hyper-methylated PCa|NT DMRs chr5158787806 158787872 0.004095673 28.38095238 Hyper-methylated PCa|NT DMRschr5 159560571 159560827 0.003093471 25.09285714 Hyper-methylated PCa|NTDMRs chr5 162998919 163318501 1.86E−05 −28.92889984 Hypo-methylatedPCa|NT DMRs chr5 167715273 167715544 6.42E−05 −40.93386243Hypo-methylated PCa|NT DMRs chr5 167775197 167782355 0.000176046−45.58008658 Hypo-methylated PCa|NT DMRs chr5 167836808 1678368820.005968871 23.28571429 Hyper-methylated PCa|NT DMRs chr5 168726818168726890 0.00023371  37.19761905 Hyper-methylated PCa|NT DMRs chr5168801252 168919140 0.000443725 −27.61111111 Hypo-methylated PCa|NT DMRschr5 170877505 170878722 5.13E−14 27.43551165 Hyper-methylated PCa|NTDMRs chr5 171023322 171023827 5.99E−06 −21.57857143 Hypo-methylatedPCa|NT DMRs chr5 171531198 171531314 0.005968871 50.60380952Hyper-methylated PCa|NT DMRs chr5 171808412 171808618 0.001969641−36.37301587 Hypo-methylated PCa|NT DMRs chr5 171880789 1718809840.00068166  28.56309524 Hyper-methylated PCa|NT DMRs chr5 171997039172013458 0.001739875 −25.56712018 Hypo-methylated PCa|NT DMRs chr5172068912 172070257 0.000564835 27.84139194 Hyper-methylated PCa|NT DMRschr5 172087043 172087243 0.001181579 29.42176871 Hyper-methylated PCa|NTDMRs chr5 172110584 172111500 9.51E−36 32.04674759 Hyper-methylatedPCa|NT DMRs chr5 172227221 172234494 0.000444042 27.75465839Hyper-methylated PCa|NT DMRs chr5 172300082 172305014 0.00013674 29.70833333 Hyper-methylated PCa|NT DMRs chr5 172327210 1723358918.62E−10 −28.2018759 Hypo-methylated PCa|NT DMRs chr5 172692358172696125 0.004505524 −20.71626984 Hypo-methylated PCa|NT DMRs chr5172754083 172754173 1.43E−05 25.79411765 Hyper-methylated PCa|NT DMRschr5 172756806 172757075 0.003218673 26.61538462 Hyper-methylated PCa|NTDMRs chr5 173191590 173193936 0.000205174 −39.85178571 Hypo-methylatedPCa|NT DMRs chr5 173291337 173293672 0.000570576 31.74126984Hyper-methylated PCa|NT DMRs chr5 173317638 173317861 0.005968871−49.3952381 Hypo-methylated PCa|NT DMRs chr5 173533377 1735936955.23E−08 −27.71128748 Hypo-methylated PCa|NT DMRs chr5 173734760173738678 0.00922177  −26.49421769 Hypo-methylated PCa|NT DMRs chr5173738735 173738778 0.005968871 27.72857143 Hyper-methylated PCa|NT DMRschr5 173814296 173834459 0.001789867 −27.86772487 Hypo-methylated PCa|NTDMRs chr5 173850763 173872341 0.000443725 −30.70198413 Hypo-methylatedPCa|NT DMRs chr5 173979531 174033581 0.00010287  −33.32142857Hypo-methylated PCa|NT DMRs chr5 174035973 174036107 0.00409567326.02380952 Hyper-methylated PCa|NT DMRs chr5 174158681 1741609429.64E−21 24.02464986 Hyper-methylated PCa|NT DMRs chr5 174643420174762038 0.000286238 −26.3697619 Hypo-methylated PCa|NT DMRs chr5175056061 175069058 0.000205174 −31.95238095 Hypo-methylated PCa|NT DMRschr5 175085419 175085716 1.12E−06 21.8015873 Hyper-methylated PCa|NTDMRs chr5 175136593 175155598 5.36E−06 −35.33452381 Hypo-methylatedPCa|NT DMRs chr5 175200325 175200399 0.00023371  21.18571429Hyper-methylated PCa|NT DMRs chr5 175604239 175614465 0.003314163−23.74285714 Hypo-methylated PCa|NT DMRs chr5 175793371 1757934090.006096657 −20.25 Hypo-methylated PCa|NT DMRs chr5 175956550 1759632120.000130675 22.02559524 Hyper-methylated PCa|NT DMRs chr5 175995834176002739 2.60E−05 −23.83571429 Hypo-methylated PCa|NT DMRs chr5176008274 176008316 0.005968871 −24.69142857 Hypo-methylated PCa|NT DMRschr5 176153803 176154061 8.36E−06 46.12328042 Hyper-methylated PCa|NTDMRs chr5 176163639 176166571 0.005526313 20.83968254 Hyper-methylatedPCa|NT DMRs chr5 176170751 176171320 4.10E−09 26.02761905Hyper-methylated PCa|NT DMRs chr5 176212655 176213169 4.41E−05−33.3984127 Hypo-methylated PCa|NT DMRs chr5 176279044 1762792020.00023371  −30.92640693 Hypo-methylated PCa|NT DMRs chr5 176289294176289950 4.29E−05 −25.96031746 Hypo-methylated PCa|NT DMRs chr5176293233 176294572 0.002950526 26.40756303 Hyper-methylated PCa|NT DMRschr5 176303302 176304269 0.008511532 20.16849817 Hyper-methylated PCa|NTDMRs chr5 176427199 176427904 0.005968871 35.82380952 Hyper-methylatedPCa|NT DMRs chr5 176543868 176544125 8.03E−08 25.63528139Hyper-methylated PCa|NT DMRs chr5 176559407 176560304 1.07E−1530.94115646 Hyper-methylated PCa|NT DMRs chr5 176754635 1767594741.24E−09 21.87467072 Hyper-methylated PCa|NT DMRs chr5 176793961176798031 8.06E−08 −33.29120879 Hypo-methylated PCa|NT DMRs chr5176808043 176812219 0.005968871 −40.90952381 Hypo-methylated PCa|NT DMRschr5 176827023 176827456 2.09E−07 −25.19835796 Hypo-methylated PCa|NTDMRs chr5 176857081 176861659 2.30E−06 38.74897959 Hyper-methylatedPCa|NT DMRs chr5 176906668 176906879 0.002822916 −24.72321429Hypo-methylated PCa|NT DMRs chr5 176934735 176936883 5.15E−1045.48711485 Hyper-methylated PCa|NT DMRs chr5 177036836 1770369380.008482405 27.1047619 Hyper-methylated PCa|NT DMRs chr5 177423236177434558 0.003829295 22.81118012 Hyper-methylated PCa|NT DMRs chr5177541206 177543945 5.22E−06 26.93316913 Hyper-methylated PCa|NT DMRschr5 177665546 177669122 6.61E−08 42.39115646 Hyper-methylated PCa|NTDMRs chr5 177669423 177669722 0.003622801 −25.66666667 Hypo-methylatedPCa|NT DMRs chr5 177811306 177811400 0.005968871 −30.03333333Hypo-methylated PCa|NT DMRs chr5 178004027 178004518 1.39E−1333.03504762 Hyper-methylated PCa|NT DMRs chr5 178068598 1781319504.67E−13 −29.28674948 Hypo-methylated PCa|NT DMRs chr5 178420361178420638 5.42E−05 30.72380952 Hyper-methylated PCa|NT DMRs chr5178420776 178421025 0.00179283  −29.48392857 Hypo-methylated PCa|NT DMRschr5 178426424 178446205 8.94E−07 −28.72993197 Hypo-methylated PCa|NTDMRs chr5 178451176 178451261 6.17E−06 26.83333333 Hyper-methylatedPCa|NT DMRs chr5 178478044 178482003 7.05E−07 −34.80654762Hypo-methylated PCa|NT DMRs chr5 178548700 178548937 2.85E−05−28.02637363 Hypo-methylated PCa|NT DMRs chr5 178553528 1785571759.23E−06 −27.80392157 Hypo-methylated PCa|NT DMRs chr5 178565002178566681 7.56E−05 −28.61247166 Hypo-methylated PCa|NT DMRs chr5178580530 178585775 1.23E−08 −26.2518315 Hypo-methylated PCa|NT DMRschr5 178594527 178598557 0.004906295 −26.25555556 Hypo-methylated PCa|NTDMRs chr5 178605205 178631811 4.32E−12 −26.33161905 Hypo-methylatedPCa|NT DMRs chr5 178635377 178636919 2.31E−05 −30.95824176Hypo-methylated PCa|NT DMRs chr5 178689164 178703505 1.10E−13−23.37579088 Hypo-methylated PCa|NT DMRs chr5 178712514 1787280147.83E−16 −30.36096799 Hypo-methylated PCa|NT DMRs chr5 178779650178793764 2.04E−09 −27.87814408 Hypo-methylated PCa|NT DMRs chr5178802025 178837641 3.29E−10 −30.3530303 Hypo-methylated PCa|NT DMRschr5 178855579 178899951 1.94E−17 −27.63369408 Hypo-methylated PCa|NTDMRs chr5 178913310 178955544 8.69E−12 −24.85962733 Hypo-methylatedPCa|NT DMRs chr5 179075628 179075889 0.005968871 −50.38857143Hypo-methylated PCa|NT DMRs chr5 179097420 179097647 0.00196964147.26587302 Hyper-methylated PCa|NT DMRs chr5 179193234 1792007820.000395643 20.49950739 Hyper-methylated PCa|NT DMRs chr5 179218651179219675 0.001969641 37.42301587 Hyper-methylated PCa|NT DMRs chr5179333400 179333543 1.97E−05 26.67142857 Hyper-methylated PCa|NT DMRschr5 179344323 179346713 0.001969641 27.69047619 Hyper-methylated PCa|NTDMRs chr5 179527452 179528960 0.000564835 −24.71575092 Hypo-methylatedPCa|NT DMRs chr5 179780971 179783246 2.99E−08 25.31207483Hyper-methylated PCa|NT DMRs chr5 179894247 179894412 0.000205174−44.60714286 Hypo-methylated PCa|NT DMRs chr5 180022975 1800235581.43E−05 −44.29579832 Hypo-methylated PCa|NT DMRs chr5 180068127180072089 4.67E−09 −20.55042735 Hypo-methylated PCa|NT DMRs chr5180072405 180072625 6.17E−06 31.67619048 Hyper-methylated PCa|NT DMRschr5 180159361 180175137 0.000377317 −25.47202381 Hypo-methylated PCa|NTDMRs chr5 180485943 180486892 7.44E−26 22.19529347 Hyper-methylatedPCa|NT DMRs chr5 180591658 180591965 0.005574525 20.93073593Hyper-methylated PCa|NT DMRs chr6 179543 179698 6.42E−05 −29.20899471Hypo-methylated PCa|NT DMRs chr6 374510 375214 0.000974795 −23.39285714Hypo-methylated PCa|NT DMRs chr6 401453 401963 4.39E−06 −26.48148148Hypo-methylated PCa|NT DMRs chr6 448943 449244 0.000199792 −21.03809524Hypo-methylated PCa|NT DMRs chr6 586206 586271 0.005968871 −47.11428571Hypo-methylated PCa|NT DMRs chr6 1599124 1602009 8.81E−06 37.46616541Hyper-methylated PCa|NT DMRs chr6 1602048 1602138 0.00091308224.81632653 Hyper-methylated PCa|NT DMRs chr6 1614192 1615653 6.67E−2534.65833333 Hyper-methylated PCa|NT DMRs chr6 1619004 1621083 6.88E−2436.56551587 Hyper-methylated PCa|NT DMRs chr6 2478053 24781810.008482405 −49.23333333 Hypo-methylated PCa|NT DMRs chr6 27532832753533 0.005968871 −35.06666667 Hypo-methylated PCa|NT DMRs chr62789228 2821488 1.84E−05 21.73351648 Hyper-methylated PCa|NT DMRs chr62841821 2858194 1.34E−17 40.56516291 Hyper-methylated PCa|NT DMRs chr63022205 3024654 2.98E−08 39.60564374 Hyper-methylated PCa|NT DMRs chr63284471 3285031 0.000847246 −38.05274725 Hypo-methylated PCa|NT DMRschr6 3438580 3438728 0.005968871 −54.2 Hypo-methylated PCa|NT DMRs chr63762809 3762975 0.005968871 −55.6 Hypo-methylated PCa|NT DMRs chr63840805 3840842 0.005968871 −59.72380952 Hypo-methylated PCa|NT DMRschr6 4078805 4079528 3.69E−05 21.59261419 Hyper-methylated PCa|NT DMRschr6 4603561 4603735 0.00064571  24.75170068 Hyper-methylated PCa|NTDMRs chr6 5026568 5026995 0.000189331 32.65151515 Hyper-methylatedPCa|NT DMRs chr6 5116366 5116739 0.008482405 −38.85714286Hypo-methylated PCa|NT DMRs chr6 6546375 6546943 1.52E−16 29.32623716Hyper-methylated PCa|NT DMRs chr6 6687243 6687653 0.002094  −22.41468254 Hypo-methylated PCa|NT DMRs chr6 6695225 66953960.005968871 29.82857143 Hyper-methylated PCa|NT DMRs chr6 72012167201456 0.00064571  −40.59183673 Hypo-methylated PCa|NT DMRs chr67236055 7237615 1.97E−05 −49.41428571 Hypo-methylated PCa|NT DMRs chr69140478 9140696 0.001969641 −57.87142857 Hypo-methylated PCa|NT DMRschr6 9971933 9976038 5.94E−06 −26.52727273 Hypo-methylated PCa|NT DMRschr6 10113590 10113704 4.45E−08 32.07619048 Hyper-methylated PCa|NT DMRschr6 10381097 10382303 6.90E−15 43.9232684 Hyper-methylated PCa|NT DMRschr6 10385142 10399289 7.81E−15 37.1681606 Hyper-methylated PCa|NT DMRschr6 10405100 10410280 4.81E−06 33.86755952 Hyper-methylated PCa|NT DMRschr6 10415766 10419590 1.85E−19 39.92361647 Hyper-methylated PCa|NT DMRschr6 10691507 10691663 0.001969641 −46.83333333 Hypo-methylated PCa|NTDMRs chr6 11154457 11154594 0.005968871 20.0047619 Hyper-methylatedPCa|NT DMRs chr6 12262604 12288668 0.007959104 −33.88707483Hypo-methylated PCa|NT DMRs chr6 13015061 13015280 0.000145366−40.30510204 Hypo-methylated PCa|NT DMRs chr6 13274132 132762500.001042833 45.01571429 Hyper-methylated PCa|NT DMRs chr6 1379766213798225 6.42E−05 −51.94179894 Hypo-methylated PCa|NT DMRs chr6 1462236614622427 0.008482405 −22.45714286 Hypo-methylated PCa|NT DMRs chr615074182 15074418 0.001969641 −30.47619048 Hypo-methylated PCa|NT DMRschr6 15222335 15222736 0.003881641 −52.50529101 Hypo-methylated PCa|NTDMRs chr6 15244752 15245034 5.53E−08 38 Hyper-methylated PCa|NT DMRschr6 15501549 15502597 0.004553481 33.15873016 Hyper-methylated PCa|NTDMRs chr6 17087054 17087115 0.005968871 −33.94761905 Hypo-methylatedPCa|NT DMRs chr6 17212939 17213148 0.000205174 −48.89285714Hypo-methylated PCa|NT DMRs chr6 17702211 17702631 0.00178986730.17460317 Hyper-methylated PCa|NT DMRs chr6 18122400 18122551 4.25E−0727.74711779 Hyper-methylated PCa|NT DMRs chr6 20024141 20024570 5.84E−0557.53571429 Hyper-methylated PCa|NT DMRs chr6 20062204 200688410.003809353 27.61190476 Hyper-methylated PCa|NT DMRs chr6 2032003120320412 0.001969641 54.65079365 Hyper-methylated PCa|NT DMRs chr621479608 21479728 0.005968871 −62.82857143 Hypo-methylated PCa|NT DMRschr6 21825744 21847664 0.001969641 52.73412698 Hyper-methylated PCa|NTDMRs chr6 25035868 25042679 0.000205174 54.375 Hyper-methylated PCa|NTDMRs chr6 26122004 26122175 6.42E−05 −30.49206349 Hypo-methylated PCa|NTDMRs chr6 26183478 26188847 3.15E−07 29.50612245 Hyper-methylated PCa|NTDMRs chr6 27173525 27173889 0.000111427 26.38809524 Hyper-methylatedPCa|NT DMRs chr6 27205735 27206537 1.55E−05 29.51490683 Hyper-methylatedPCa|NT DMRs chr6 27279861 27280084 0.000632596 26.83116883Hyper-methylated PCa|NT DMRs chr6 27555535 27555849 0.005968871−32.13619048 Hypo-methylated PCa|NT DMRs chr6 27730428 277399470.009924186 −26.18730159 Hypo-methylated PCa|NT DMRs chr6 2779864927798699 0.008234951 33.76571429 Hyper-methylated PCa|NT DMRs chr627832041 27832231 0.005968871 27.54285714 Hyper-methylated PCa|NT DMRschr6 27940212 27983636 0.000771292 −26.36446886 Hypo-methylated PCa|NTDMRs chr6 28131798 28143819 6.42E−05 −23.28571429 Hypo-methylated PCa|NTDMRs chr6 28740454 28744031 1.60E−16 20.47741935 Hyper-methylated PCa|NTDMRs chr6 28833281 28833678 0.003702731 −22.88095238 Hypo-methylatedPCa|NT DMRs chr6 28956466 28956666 5.94E−06 33.17229437 Hyper-methylatedPCa|NT DMRs chr6 29541910 29589632 0.000370938 −22.4047619Hypo-methylated PCa|NT DMRs chr6 29595299 29595695 1.29E−05 24.36521739Hyper-methylated PCa|NT DMRs chr6 29942977 29943409 6.42E−05 43.75661376Hyper-methylated PCa|NT DMRs chr6 30466509 30466709 0.000205174−28.32142857 Hypo-methylated PCa|NT DMRs chr6 30649262 30653871 4.26E−1338.77073171 Hyper-methylated PCa|NT DMRs chr6 30710878 30712542 3.13E−2130.53610519 Hyper-methylated PCa|NT DMRs chr6 30852823 308541620.005968871 −28.15714286 Hypo-methylated PCa|NT DMRs chr6 3090267530920836 0.009924186 −22.01587302 Hypo-methylated PCa|NT DMRs chr631166348 31170470 0.003809353 31.44047619 Hyper-methylated PCa|NT DMRschr6 31276303 31276798 3.85E−08 27.8752381 Hyper-methylated PCa|NT DMRschr6 31525861 31528136 3.44E−06 42.26755952 Hyper-methylated PCa|NT DMRschr6 31539735 31540201 0.000226774 20.65396825 Hyper-methylated PCa|NTDMRs chr6 31650760 31650877 0.000137206 21.28730159 Hyper-methylatedPCa|NT DMRs chr6 31830234 31831639 2.49E−21 26.98251488 Hyper-methylatedPCa|NT DMRs chr6 31844592 31848535 0.00023371  −34.2680776Hypo-methylated PCa|NT DMRs chr6 32847660 32847758 0.00064571 25.87755102 Hyper-methylated PCa|NT DMRs chr6 33245438 33246044 1.44E−0536.3968254 Hyper-methylated PCa|NT DMRs chr6 33282713 33283190 1.68E−07−28.75446429 Hypo-methylated PCa|NT DMRs chr6 33398866 334017610.001400829 29.54761905 Hyper-methylated PCa|NT DMRs chr6 3350124333501502 0.000396159 24.21190476 Hyper-methylated PCa|NT DMRs chr633519032 33519095 0.003448944 −38.57823129 Hypo-methylated PCa|NT DMRschr6 33560929 33561176 1.42E−05 23.45748299 Hyper-methylated PCa|NT DMRschr6 33657868 33664376 0.000357616 25.68903319 Hyper-methylated PCa|NTDMRs chr6 33848721 33848882 0.001969641 −35.80952381 Hypo-methylatedPCa|NT DMRs chr6 33927011 33943838 0.001969641 35.24206349Hyper-methylated PCa|NT DMRs chr6 34033937 34033991 0.001969641−53.0952381 Hypo-methylated PCa|NT DMRs chr6 34191048 341914930.000328483 −28.32380952 Hypo-methylated PCa|NT DMRs chr6 3463423134640215 6.42E−05 26.98941799 Hyper-methylated PCa|NT DMRs chr6 3510887935109894 9.59E−06 20.07722008 Hyper-methylated PCa|NT DMRs chr6 3514551335181430 0.00012477  20.32553191 Hyper-methylated PCa|NT DMRs chr635182352 35182816 0.00028029  21.97587302 Hyper-methylated PCa|NT DMRschr6 35453935 35454394 1.33E−17 −50.04069264 Hypo-methylated PCa|NT DMRschr6 35471346 35471404 6.42E−05 50.57142857 Hyper-methylated PCa|NT DMRschr6 35679117 35688612 0.006225823 31.11428571 Hyper-methylated PCa|NTDMRs chr6 35698308 35698376 0.005968871 35.2 Hyper-methylated PCa|NTDMRs chr6 36703335 36703676 0.000205174 −28.96428571 Hypo-methylatedPCa|NT DMRs chr6 36737479 36738133 3.39E−05 41.62554113 Hyper-methylatedPCa|NT DMRs chr6 36799121 36807496 0.00098106  24.6752381Hyper-methylated PCa|NT DMRs chr6 36929879 36930841 2.01E−05 29.85595238Hyper-methylated PCa|NT DMRs chr6 37483710 37484986 0.000117699−36.5961039 Hypo-methylated PCa|NT DMRs chr6 37750852 37751717 2.82E−0939.7485348 Hyper-methylated PCa|NT DMRs chr6 39194632 39196450 5.91E−0835.98015873 Hyper-methylated PCa|NT DMRs chr6 39964783 39990818 1.31E−06−25.0521164 Hypo-methylated PCa|NT DMRs chr6 40114717 40249785 3.32E−06−30.84960317 Hypo-methylated PCa|NT DMRs chr6 40846175 408806370.005436464 −24.50250627 Hypo-methylated PCa|NT DMRs chr6 4115381741153975 0.000822388 24.84285714 Hyper-methylated PCa|NT DMRs chr641394852 41395312 0.001580415 36.15108225 Hyper-methylated PCa|NT DMRschr6 41437525 41438869 2.36E−06 26.49887218 Hyper-methylated PCa|NT DMRschr6 41460262 41471123 0.000812507 26.69142857 Hyper-methylated PCa|NTDMRs chr6 41472290 41472432 0.007563547 23.48268398 Hyper-methylatedPCa|NT DMRs chr6 41473448 41496061 0.000219662 −27.72420635Hypo-methylated PCa|NT DMRs chr6 41528285 41529051 1.60E−10 47.8Hyper-methylated PCa|NT DMRs chr6 41604500 41605021 1.67E−08−25.06515679 Hypo-methylated PCa|NT DMRs chr6 41605297 41607280 1.05E−2429.75810594 Hyper-methylated PCa|NT DMRs chr6 41903506 419050470.003448944 36.15306122 Hyper-methylated PCa|NT DMRs chr6 4197567841978553 6.42E−05 51.61904762 Hyper-methylated PCa|NT DMRs chr6 4201596742016245 0.000974795 21.32142857 Hyper-methylated PCa|NT DMRs chr642067286 42067648 0.000205174 −44.09583333 Hypo-methylated PCa|NT DMRschr6 42247165 42247373 0.001969641 47.51587302 Hyper-methylated PCa|NTDMRs chr6 42387065 42397211 0.00641359  59.08174603 Hyper-methylatedPCa|NT DMRs chr6 42521978 42522140 1.27E−06 29.84166667 Hyper-methylatedPCa|NT DMRs chr6 42878755 42883814 0.001235857 20.39466667Hyper-methylated PCa|NT DMRs chr6 43235516 43235576 0.001969641 −48.5Hypo-methylated PCa|NT DMRs chr6 43237315 43243045 1.63E−09 24.83333333Hyper-methylated PCa|NT DMRs chr6 43276295 43276479 0.00196964122.33333333 Hyper-methylated PCa|NT DMRs chr6 43612900 43613077 3.32E−0620.6547619 Hyper-methylated PCa|NT DMRs chr6 43670519 436707380.005968871 32.22380952 Hyper-methylated PCa|NT DMRs chr6 4375546543796596 8.73E−05 33.14217687 Hyper-methylated PCa|NT DMRs chr6 4396677143971921 2.52E−07 25.18606702 Hyper-methylated PCa|NT DMRs chr6 4418664944187596 5.52E−05 22.53251232 Hyper-methylated PCa|NT DMRs chr6 4419935244201403 0.00064571  45.55102041 Hyper-methylated PCa|NT DMRs chr644524551 44529286 2.02E−05 31.82804233 Hyper-methylated PCa|NT DMRs chr644621542 44621871 0.000205174 41.67083333 Hyper-methylated PCa|NT DMRschr6 45390683 45399745 6.77E−23 25.78634921 Hyper-methylated PCa|NT DMRschr6 48696432 48842884 3.55E−06 −23.42089947 Hypo-methylated PCa|NT DMRschr6 49047159 49270558 0.001241245 −26.66719577 Hypo-methylated PCa|NTDMRs chr6 49953415 49993384 0.000481535 −33.3994709 Hypo-methylatedPCa|NT DMRs chr6 50784964 50785335 5.94E−06 41.07792208 Hyper-methylatedPCa|NT DMRs chr6 50787591 50817375 3.96E−32 26.77379078 Hyper-methylatedPCa|NT DMRs chr6 52227389 52228001 6.01E−15 20.91661376 Hyper-methylatedPCa|NT DMRs chr6 52268531 52268827 0.00064571  −46.86734694Hypo-methylated PCa|NT DMRs chr6 52408933 52409436 0.001969641−35.46598639 Hypo-methylated PCa|NT DMRs chr6 53590475 536026790.002585277 −31.29761905 Hypo-methylated PCa|NT DMRs chr6 5420324154602028 2.96E−08 −37.13066667 Hypo-methylated PCa|NT DMRs chr6 5472395154874279 1.18E−08 −36.97777778 Hypo-methylated PCa|NT DMRs chr6 5493731755010509 0.003871035 −30.91468254 Hypo-methylated PCa|NT DMRs chr655104788 55104870 0.000149331 −36.87445887 Hypo-methylated PCa|NT DMRschr6 56716301 56716682 0.000319085 38.20119048 Hyper-methylated PCa|NTDMRs chr6 61902245 62843838 3.13E−20 −29.69627976 Hypo-methylated PCa|NTDMRs chr6 63202472 63809696 5.42E−12 −29.70171958 Hypo-methylated PCa|NTDMRs chr6 63963112 64042810 3.14E−10 −27.84801587 Hypo-methylated PCa|NTDMRs chr6 69201704 69255766 2.52E−06 −34.54705882 Hypo-methylated PCa|NTDMRs chr6 69514944 69650669 8.31E−07 −31.77804233 Hypo-methylated PCa|NTDMRs chr6 71039492 71085942 0.000354065 −24.01111111 Hypo-methylatedPCa|NT DMRs chr6 71815029 71874731 5.94E−06 −30.82034632 Hypo-methylatedPCa|NT DMRs chr6 72299560 72498578 1.49E−06 −28.33658009 Hypo-methylatedPCa|NT DMRs chr6 73330693 73331680 1.26E−16 25.21499118 Hyper-methylatedPCa|NT DMRs chr6 75911644 75912132 1.55E−08 20.56 Hyper-methylatedPCa|NT DMRs chr6 76059043 76059735 6.69E−05 23.08904762 Hyper-methylatedPCa|NT DMRs chr6 81368678 81371686 4.90E−08 −25.69718615 Hypo-methylatedPCa|NT DMRs chr6 81647266 82051004 8.76E−21 −30.56014652 Hypo-methylatedPCa|NT DMRs chr6 84485488 84521569 0.001969641 −29.50238095Hypo-methylated PCa|NT DMRs chr6 84954352 85426573 4.03E−13 −27.63938492Hypo-methylated PCa|NT DMRs chr6 88450700 88450769 0.004095673−51.38095238 Hypo-methylated PCa|NT DMRs chr6 88757426 887574690.00064571  22.83333333 Hyper-methylated PCa|NT DMRs chr6 8880316488818352 0.005513661 −24.28869048 Hypo-methylated PCa|NT DMRs chr690116046 90120255 0.00170819  35.18315018 Hyper-methylated PCa|NT DMRschr6 96572120 96709167 3.15E−07 −22.00816327 Hypo-methylated PCa|NT DMRschr6 97362727 97362869 0.005968871 −28.25714286 Hypo-methylated PCa|NTDMRs chr6 97558432 97562194 0.004236974 26.75666667 Hyper-methylatedPCa|NT DMRs chr6 99699790 99703151 0.001969641 −23.9984127Hypo-methylated PCa|NT DMRs chr6 100098671 100423544 5.84E−05−25.63730159 Hypo-methylated PCa|NT DMRs chr6 101113322 1011609820.007959104 −34.26530612 Hypo-methylated PCa|NT DMRs chr6 104474230104588399 0.000118733 −22.54656085 Hypo-methylated PCa|NT DMRs chr6105525000 105534993 0.00641359  −27.90873016 Hypo-methylated PCa|NT DMRschr6 107426718 107426941 0.00179283  30.91785714 Hyper-methylated PCa|NTDMRs chr6 107527465 107550579 0.005968871 −26.09428571 Hypo-methylatedPCa|NT DMRs chr6 109267275 109274465 0.000137206 −29.66857143Hypo-methylated PCa|NT DMRs chr6 109768430 109770784 0.005968871−20.49659864 Hypo-methylated PCa|NT DMRs chr6 112627011 1126714080.000406444 −22.66530612 Hypo-methylated PCa|NT DMRs chr6 114181300114181445 6.93E−06 −30.48 Hypo-methylated PCa|NT DMRs chr6 115849822116137038 0.000549619 −20.6026455 Hypo-methylated PCa|NT DMRs chr6116783000 116783480 8.07E−14 27.44642857 Hyper-methylated PCa|NT DMRschr6 117807999 117869525 7.79E−05 23.67413793 Hyper-methylated PCa|NTDMRs chr6 121069769 121069819 0.00064571  −26.33061224 Hypo-methylatedPCa|NT DMRs chr6 123318725 124050907 9.39E−12 −32.97692308Hypo-methylated PCa|NT DMRs chr6 124134391 125000397 7.40E−16−32.84366577 Hypo-methylated PCa|NT DMRs chr6 126682514 1270557711.76E−10 −25.01034014 Hypo-methylated PCa|NT DMRs chr6 127314560127415333 5.37E−05 −32.63595238 Hypo-methylated PCa|NT DMRs chr6129204125 129204541 2.73E−06 27.78677249 Hyper-methylated PCa|NT DMRschr6 129251213 129251341 5.36E−09 33.04395604 Hyper-methylated PCa|NTDMRs chr6 132249752 132270549 0.001969641 −29.04365079 Hypo-methylatedPCa|NT DMRs chr6 132850730 132970219 3.48E−07 −38.35095238Hypo-methylated PCa|NT DMRs chr6 133307565 133355928 0.00064571 −37.67006803 Hypo-methylated PCa|NT DMRs chr6 133375149 1335596067.37E−05 −30.5535014 Hypo-methylated PCa|NT DMRs chr6 133601782134012715 5.85E−12 −31.2981982 Hypo-methylated PCa|NT DMRs chr6134436382 134436761 6.79E−07 23.37987013 Hyper-methylated PCa|NT DMRschr6 137241530 137242368 0.000335989 28.41208791 Hyper-methylated PCa|NTDMRs chr6 137834594 137834650 0.000974795 34.91071429 Hyper-methylatedPCa|NT DMRs chr6 138723259 138724700 0.002298126 25.79271709Hyper-methylated PCa|NT DMRs chr6 140018202 140018442 0.00596887132.37142857 Hyper-methylated PCa|NT DMRs chr6 142409729 1424098783.09E−06 22.65986395 Hyper-methylated PCa|NT DMRs chr6 143175102143231911 0.002193447 23.98008658 Hyper-methylated PCa|NT DMRs chr6143247670 143248408 1.51E−13 21.9982684 Hyper-methylated PCa|NT DMRschr6 144585545 144587623 0.005968871 −48.99047619 Hypo-methylated PCa|NTDMRs chr6 148639792 148639837 0.005968871 −28.71428571 Hypo-methylatedPCa|NT DMRs chr6 149772376 149772825 1.42E−09 31.42593985Hyper-methylated PCa|NT DMRs chr6 151134596 151134787 0.00064571 −39.7877551 Hypo-methylated PCa|NT DMRs chr6 151187747 1511881056.50E−05 28.16770186 Hyper-methylated PCa|NT DMRs chr6 151345821151358206 8.51E−05 −42.96825397 Hypo-methylated PCa|NT DMRs chr6151365732 151388380 0.00020572  −41.08571429 Hypo-methylated PCa|NT DMRschr6 154375360 154532518 8.73E−08 −32.4687619 Hypo-methylated PCa|NTDMRs chr6 155649902 156380644 6.21E−26 −35.32424242 Hypo-methylatedPCa|NT DMRs chr6 156407322 156472820 2.86E−05 −29.87728938Hypo-methylated PCa|NT DMRs chr6 156651838 156660827 0.000205174−30.66130952 Hypo-methylated PCa|NT DMRs chr6 157931773 1579321491.76E−06 41.6547619 Hyper-methylated PCa|NT DMRs chr6 158056754158066619 0.005968871 20.27619048 Hyper-methylated PCa|NT DMRs chr6158185614 158185714 0.005968871 40.99619048 Hyper-methylated PCa|NT DMRschr6 158245997 158274880 0.003871035 −42.28571429 Hypo-methylated PCa|NTDMRs chr6 158406555 158409199 1.76E−06 −51.29325397 Hypo-methylatedPCa|NT DMRs chr6 158411822 158438202 7.30E−05 −34.49455782Hypo-methylated PCa|NT DMRs chr6 158506919 158508118 7.04E−0737.25687831 Hyper-methylated PCa|NT DMRs chr6 158984337 1589913893.25E−05 27.95918367 Hyper-methylated PCa|NT DMRs chr6 159360182159360918 4.45E−08 36.63396825 Hyper-methylated PCa|NT DMRs chr6159589597 159590220 8.46E−05 30.54786967 Hyper-methylated PCa|NT DMRschr6 160308058 160337843 0.000121459 −21.14891775 Hypo-methylated PCa|NTDMRs chr6 163570125 163570311 2.01E−07 29.73642857 Hyper-methylatedPCa|NT DMRs chr6 163756801 163757154 9.92E−08 26.80272109Hyper-methylated PCa|NT DMRs chr6 163817972 163818111 0.005968871 29.4Hyper-methylated PCa|NT DMRs chr6 164012325 164030391 5.19E−07−21.50309524 Hypo-methylated PCa|NT DMRs chr6 164322022 1643405266.42E−05 −27.47830688 Hypo-methylated PCa|NT DMRs chr6 164379301164393089 7.34E−09 −25.41318681 Hypo-methylated PCa|NT DMRs chr6164480017 164506646 5.79E−09 −31.47066667 Hypo-methylated PCa|NT DMRschr6 164525276 164527551 0.000974795 −32.78869048 Hypo-methylated PCa|NTDMRs chr6 164587673 164638187 0.00023371  −29.73761905 Hypo-methylatedPCa|NT DMRs chr6 166218123 166218821 1.23E−10 25.0032175Hyper-methylated PCa|NT DMRs chr6 166419013 166422172 1.86E−0923.04761905 Hyper-methylated PCa|NT DMRs chr6 166582369 1665831801.23E−12 31.18582503 Hyper-methylated PCa|NT DMRs chr6 166682087166685722 0.003174366 −27.7610119 Hypo-methylated PCa|NT DMRs chr6166746974 166747097 0.001583444 40.73214286 Hyper-methylated PCa|NT DMRschr6 166853680 166855458 2.84E−06 50.11160714 Hyper-methylated PCa|NTDMRs chr6 166901692 166901855 2.85E−05 55.61538462 Hyper-methylatedPCa|NT DMRs chr6 166976448 166976809 0.009924186 26.13492063Hyper-methylated PCa|NT DMRs chr6 167038855 167039292 0.001969641−53.38095238 Hypo-methylated PCa|NT DMRs chr6 167070040 1670882500.003003689 21.6602381 Hyper-methylated PCa|NT DMRs chr6 167171091167171454 0.00064571  30.60204082 Hyper-methylated PCa|NT DMRs chr6167248198 167250731 3.20E−05 −36.74659864 Hypo-methylated PCa|NT DMRschr6 167312336 167312423 0.00064571  −29.85306122 Hypo-methylated PCa|NTDMRs chr6 167559852 167559889 0.005968871 21.94857143 Hyper-methylatedPCa|NT DMRs chr6 168106965 168113392 0.000733783 29.87142857Hyper-methylated PCa|NT DMRs chr6 168333306 168333467 0.005968871−29.76666667 Hypo-methylated PCa|NT DMRs chr6 168785142 1687885270.000123403 22.69423559 Hyper-methylated PCa|NT DMRs chr6 168789291168789748 3.44E−06 −41.31845238 Hypo-methylated PCa|NT DMRs chr6168843001 168843280 5.92E−06 38.73529412 Hyper-methylated PCa|NT DMRschr6 169048991 169049164 0.00641359  −40.80952381 Hypo-methylated PCa|NTDMRs chr6 169226418 169226880 4.48E−06 −34.74285714 Hypo-methylatedPCa|NT DMRs chr6 169291050 169295971 0.006410012 −30.21626984Hypo-methylated PCa|NT DMRs chr6 169435560 169476311 3.42E−07−24.97414966 Hypo-methylated PCa|NT DMRs chr6 169487414 1694976613.30E−05 −22.87936508 Hypo-methylated PCa|NT DMRs chr6 169542058169558202 0.00027677  −28.80952381 Hypo-methylated PCa|NT DMRs chr6169569524 169569685 0.001969641 −36.62380952 Hypo-methylated PCa|NT DMRschr6 169640238 169640606 0.000481535 −44.37037037 Hypo-methylated PCa|NTDMRs chr6 169740755 169741075 0.004326525 −20.81428571 Hypo-methylatedPCa|NT DMRs chr6 169778035 169780994 8.70E−08 −21.76818182Hypo-methylated PCa|NT DMRs chr6 170338190 170338768 3.06E−0625.13928571 Hyper-methylated PCa|NT DMRs chr6 170403221 1704039940.00179283  36.93452381 Hyper-methylated PCa|NT DMRs chr6 170467172170467502 2.86E−05 37.10989011 Hyper-methylated PCa|NT DMRs chr6170535578 170535928 0.000190021 −42.51212121 Hypo-methylated PCa|NT DMRschr6 170556386 170557261 0.001974972 −22.63180952 Hypo-methylated PCa|NTDMRs chr6 170573899 170575017 6.50E−05 −47.21428571 Hypo-methylatedPCa|NT DMRs chr6 170578845 170581299 6.79E−07 39.63593074Hyper-methylated PCa|NT DMRs chr6 170581883 170586134 4.47E−08−24.48757764 Hypo-methylated PCa|NT DMRs chr7 85568 85990 0.001985874−43.95714286 Hypo-methylated PCa|NT DMRs chr7 119273 119967 0.00130558544.37142857 Hyper-methylated PCa|NT DMRs chr7 149899 150928 0.00369512 24.17482993 Hyper-methylated PCa|NT DMRs chr7 184901 185316 4.43E−05−22.12051282 Hypo-methylated PCa|NT DMRs chr7 329190 329782 8.21E−0822.08046398 Hyper-methylated PCa|NT DMRs chr7 334699 334741 0.001969641−26.44444444 Hypo-methylated PCa|NT DMRs chr7 373002 373649 2.49E−07−21.49546485 Hypo-methylated PCa|NT DMRs chr7 381545 382340 3.82E−05−42.93641457 Hypo-methylated PCa|NT DMRs chr7 391295 392268 9.27E−0536.38765432 Hyper-methylated PCa|NT DMRs chr7 396939 400660 1.67E−0731.06316527 Hyper-methylated PCa|NT DMRs chr7 412912 413113 0.00376498226.35238095 Hyper-methylated PCa|NT DMRs chr7 415787 416459 0.00186785323.9415873 Hyper-methylated PCa|NT DMRs chr7 419885 420252 0.00011769928.20779221 Hyper-methylated PCa|NT DMRs chr7 474810 476132 4.28E−07−36.60194805 Hypo-methylated PCa|NT DMRs chr7 481826 484931 0.005513661−21.82108844 Hypo-methylated PCa|NT DMRs chr7 560525 561356 1.80E−1029.41608752 Hyper-methylated PCa|NT DMRs chr7 577782 578623 0.00071546134.45238095 Hyper-methylated PCa|NT DMRs chr7 601162 601454 2.39E−05−39.30357143 Hypo-methylated PCa|NT DMRs chr7 614047 614943 0.001083007−32.50952381 Hypo-methylated PCa|NT DMRs chr7 630473 630878 3.06E−0837.62215321 Hyper-methylated PCa|NT DMRs chr7 630960 631133 0.00596887133.66507937 Hyper-methylated PCa|NT DMRs chr7 632596 633218 6.10E−0542.30805861 Hyper-methylated PCa|NT DMRs chr7 641029 645781 6.70E−1840.15189873 Hyper-methylated PCa|NT DMRs chr7 676117 676781 0.000339627−30.45674603 Hypo-methylated PCa|NT DMRs chr7 744822 745664 0.001969641−59.55442177 Hypo-methylated PCa|NT DMRs chr7 752307 752522 1.34E−0522.57142857 Hyper-methylated PCa|NT DMRs chr7 771824 779037 5.56E−05−33.00779221 Hypo-methylated PCa|NT DMRs chr7 953489 954045 0.001836065−24.38988095 Hypo-methylated PCa|NT DMRs chr7 959664 960120 3.05E−06−29.72681704 Hypo-methylated PCa|NT DMRs chr7 961836 965813 3.90E−1128.92721088 Hyper-methylated PCa|NT DMRs chr7 968401 971926 0.00355340720.47994987 Hyper-methylated PCa|NT DMRs chr7 997743 997911 0.00196964152.35102041 Hyper-methylated PCa|NT DMRs chr7 1021911 10222000.00023371  −40.72285714 Hypo-methylated PCa|NT DMRs chr7 10278981028614 5.13E−07 21.77077176 Hyper-methylated PCa|NT DMRs chr7 10518461052439 1.35E−06 27.77639752 Hyper-methylated PCa|NT DMRs chr7 10952551096685 3.29E−05 32.22893773 Hyper-methylated PCa|NT DMRs chr7 11000491105373 0.002992764 23.22228571 Hyper-methylated PCa|NT DMRs chr71147387 1147964 0.005574525 34.02121212 Hyper-methylated PCa|NT DMRschr7 1184345 1184685 0.000169316 −25.50396825 Hypo-methylated PCa|NTDMRs chr7 1217681 1220518 6.35E−06 −23.27910053 Hypo-methylated PCa|NTDMRs chr7 1270161 1270186 0.001969641 29.38095238 Hyper-methylatedPCa|NT DMRs chr7 1273389 1273439 0.001181579 21.91836735Hyper-methylated PCa|NT DMRs chr7 1273584 1273629 0.00020517427.36369048 Hyper-methylated PCa|NT DMRs chr7 1301746 1303468 6.60E−05−35.12321429 Hypo-methylated PCa|NT DMRs chr7 1314101 13146080.002301155 −21.63389356 Hypo-methylated PCa|NT DMRs chr7 13147181315879 2.67E−12 −28.42898914 Hypo-methylated PCa|NT DMRs chr7 13332801333725 3.20E−05 −24.82417582 Hypo-methylated PCa|NT DMRs chr7 13362921337384 0.000474458 −24.77582418 Hypo-methylated PCa|NT DMRs chr71362259 1362825 0.001431904 −22.53928571 Hypo-methylated PCa|NT DMRschr7 1409656 1415820 0.000447319 −20.1347619 Hypo-methylated PCa|NT DMRschr7 1422820 1423916 0.000226106 −29.77086835 Hypo-methylated PCa|NTDMRs chr7 1493108 1495340 3.51E−05 −32.90357143 Hypo-methylated PCa|NTDMRs chr7 1503838 1504468 7.19E−05 −48.90714286 Hypo-methylated PCa|NTDMRs chr7 1548974 1553567 3.11E−11 31.8637827 Hyper-methylated PCa|NTDMRs chr7 1556337 1562593 0.00013312  −33.9484127 Hypo-methylated PCa|NTDMRs chr7 1563266 1569378 7.74E−05 −20.02738095 Hypo-methylated PCa|NTDMRs chr7 1594787 1595521 2.83E−09 −38.16316527 Hypo-methylated PCa|NTDMRs chr7 1707639 1708142 0.000234237 30.49761905 Hyper-methylatedPCa|NT DMRs chr7 1708710 1709430 2.74E−15 30.91932773 Hyper-methylatedPCa|NT DMRs chr7 1753263 1756033 0.000457395 −41.96666667Hypo-methylated PCa|NT DMRs chr7 1772890 1774810 3.96E−08 −33.99923195Hypo-methylated PCa|NT DMRs chr7 1775035 1777564 0.000205174 −26.625Hypo-methylated PCa|NT DMRs chr7 1858682 1858749 0.005968871 −41.1647619Hypo-methylated PCa|NT DMRs chr7 1883642 1883877 0.003871035 22.5922619Hyper-methylated PCa|NT DMRs chr7 1957050 1957383 0.000286238−21.27692308 Hypo-methylated PCa|NT DMRs chr7 1978508 1982391 1.60E−1236.09398496 Hyper-methylated PCa|NT DMRs chr7 2057136 20600400.00011419  32.45052265 Hyper-methylated PCa|NT DMRs chr7 21060602106454 4.41E−05 29.33650794 Hyper-methylated PCa|NT DMRs chr7 21134872113695 0.000836132 −37.87301587 Hypo-methylated PCa|NT DMRs chr72114270 2114928 2.99E−09 35.52488479 Hyper-methylated PCa|NT DMRs chr72119341 2119557 0.00064571  44.47278912 Hyper-methylated PCa|NT DMRschr7 2208381 2208893 0.000456684 −25.11388889 Hypo-methylated PCa|NTDMRs chr7 2285423 2286439 0.003314163 32.63952381 Hyper-methylatedPCa|NT DMRs chr7 2286667 2287104 0.002988739 −29.11831502Hypo-methylated PCa|NT DMRs chr7 2289038 2289256 6.71E−06 43.08035714Hyper-methylated PCa|NT DMRs chr7 2473806 2474104 0.000205174−35.16369048 Hypo-methylated PCa|NT DMRs chr7 2511042 25114320.00046742  26.66753247 Hyper-methylated PCa|NT DMRs chr7 25375322537948 0.00064571  41.05782313 Hyper-methylated PCa|NT DMRs chr72558419 2558676 2.96E−08 35.78829365 Hyper-methylated PCa|NT DMRs chr72568432 2570933 8.26E−09 39.8092437 Hyper-methylated PCa|NT DMRs chr72570956 2571642 2.41E−08 −53.54099379 Hypo-methylated PCa|NT DMRs chr72602923 2607550 0.003032307 26.08163265 Hyper-methylated PCa|NT DMRschr7 2646739 2646946 0.001969641 29.61904762 Hyper-methylated PCa|NTDMRs chr7 2663043 2663337 0.003871035 31.13095238 Hyper-methylatedPCa|NT DMRs chr7 2669951 2670124 0.000974795 −43.09285714Hypo-methylated PCa|NT DMRs chr7 2677315 2677563 8.17E−05 38.81818182Hyper-methylated PCa|NT DMRs chr7 2681361 2683061 0.00034026426.02678571 Hyper-methylated PCa|NT DMRs chr7 2683140 26834690.008581782 −21.19444444 Hypo-methylated PCa|NT DMRs chr7 27186972719488 5.43E−07 −48.40827068 Hypo-methylated PCa|NT DMRs chr7 27199302722738 0.000634922 −22.72380952 Hypo-methylated PCa|NT DMRs chr72738855 2738926 0.002826041 21.16326531 Hyper-methylated PCa|NT DMRschr7 2774474 2776358 2.96E−06 45.09187675 Hyper-methylated PCa|NT DMRschr7 2848597 2848762 0.000481535 29.41587302 Hyper-methylated PCa|NTDMRs chr7 2866860 2872955 0.001344447 20.83988095 Hyper-methylatedPCa|NT DMRs chr7 2899611 2900193 0.001480644 −36.78190476Hypo-methylated PCa|NT DMRs chr7 2934456 2934513 0.005968871 50.6Hyper-methylated PCa|NT DMRs chr7 2943499 2946005 0.002656308−29.68170426 Hypo-methylated PCa|NT DMRs chr7 2963037 2966354 8.46E−05−25.28195489 Hypo-methylated PCa|NT DMRs chr7 2993837 29992270.00179283  29.57142857 Hyper-methylated PCa|NT DMRs chr7 30183923020589 4.43E−10 43.97012987 Hyper-methylated PCa|NT DMRs chr7 30332613033409 0.001969641 −50.71428571 Hypo-methylated PCa|NT DMRs chr73221067 3221409 0.00064571  −65.82993197 Hypo-methylated PCa|NT DMRschr7 3279063 3286550 0.001451125 −31.67952381 Hypo-methylated PCa|NTDMRs chr7 3622737 3622977 0.003622801 −32.55952381 Hypo-methylatedPCa|NT DMRs chr7 4248708 4250972 0.001684481 22.97619048Hyper-methylated PCa|NT DMRs chr7 4365334 4456378 8.92E−06 −24.25204082Hypo-methylated PCa|NT DMRs chr7 4653071 4653579 0.007560755 21.3968254Hyper-methylated PCa|NT DMRs chr7 4663826 4675953 0.000976859−21.2858631 Hypo-methylated PCa|NT DMRs chr7 4729083 4734698 0.002094  −20.44047619 Hypo-methylated PCa|NT DMRs chr7 4848822 4849577 1.31E−0648.67936508 Hyper-methylated PCa|NT DMRs chr7 4863232 48634720.005968871 41.79047619 Hyper-methylated PCa|NT DMRs chr7 48854964885578 0.000205174 41.73214286 Hyper-methylated PCa|NT DMRs chr74920374 4922909 9.84E−08 22.64993895 Hyper-methylated PCa|NT DMRs chr74955678 4960035 0.005513661 −41.75986395 Hypo-methylated PCa|NT DMRschr7 5111823 5112718 7.54E−05 21.46190476 Hyper-methylated PCa|NT DMRschr7 5184143 5184310 0.000133627 22.9914966 Hyper-methylated PCa|NT DMRschr7 5214077 5214408 0.009503366 −20.89285714 Hypo-methylated PCa|NTDMRs chr7 5243356 5243408 1.97E−05 −31.65238095 Hypo-methylated PCa|NTDMRs chr7 5313665 5314228 0.00064571  −46.08163265 Hypo-methylatedPCa|NT DMRs chr7 5436680 5452873 0.005480955 21.23414966Hyper-methylated PCa|NT DMRs chr7 5510402 5510923 5.60E−06 −20.54797178Hypo-methylated PCa|NT DMRs chr7 5527669 5528127 2.74E−05 37.46691729Hyper-methylated PCa|NT DMRs chr7 5535253 5535937 1.38E−07 −42.00186335Hypo-methylated PCa|NT DMRs chr7 5613487 5614661 0.007222512 20.06135531Hyper-methylated PCa|NT DMRs chr7 5626136 5626374 0.001181579−44.73469388 Hypo-methylated PCa|NT DMRs chr7 5734835 57417220.000121459 29.80411255 Hyper-methylated PCa|NT DMRs chr7 60349636035755 0.001241245 −39.13227513 Hypo-methylated PCa|NT DMRs chr76199980 6203156 0.00179283  −40.17559524 Hypo-methylated PCa|NT DMRschr7 6435794 6437019 0.002580892 34.08134921 Hyper-methylated PCa|NTDMRs chr7 6458922 6459091 0.005968871 −50.34857143 Hypo-methylatedPCa|NT DMRs chr7 6463204 6465027 1.04E−05 31.36645022 Hyper-methylatedPCa|NT DMRs chr7 6474566 6475282 0.002697142 26.12328042Hyper-methylated PCa|NT DMRs chr7 6600894 6611746 0.001789867−27.57936508 Hypo-methylated PCa|NT DMRs chr7 6882006 68921660.00118504  −29.72142857 Hypo-methylated PCa|NT DMRs chr7 69307156934354 0.00064571  −22.09659864 Hypo-methylated PCa|NT DMRs chr78456923 8463768 0.001969641 −25.02380952 Hypo-methylated PCa|NT DMRschr7 9730523 9753072 0.00641359  −25.63809524 Hypo-methylated PCa|NTDMRs chr7 11012954 11013130 0.001146289 −37.92857143 Hypo-methylatedPCa|NT DMRs chr7 14411827 14735428 2.15E−05 −21.86848073 Hypo-methylatedPCa|NT DMRs chr7 15626429 15688034 0.00064571  −28.39795918Hypo-methylated PCa|NT DMRs chr7 15725474 15726527 5.01E−08 20.97248677Hyper-methylated PCa|NT DMRs chr7 15726835 15727139 0.00196964121.54365079 Hyper-methylated PCa|NT DMRs chr7 16890636 168908710.000974795 36.07142857 Hyper-methylated PCa|NT DMRs chr7 1800108918054101 3.82E−07 −23.41888889 Hypo-methylated PCa|NT DMRs chr7 1814370618387381 2.12E−06 −25.15 Hypo-methylated PCa|NT DMRs chr7 1883300618833085 0.004095673 −26.97619048 Hypo-methylated PCa|NT DMRs chr722590069 22590220 0.002097193 24.91836735 Hyper-methylated PCa|NT DMRschr7 23530109 23530453 6.93E−06 40.55396825 Hyper-methylated PCa|NT DMRschr7 25569063 25584298 0.000118733 −31.11322751 Hypo-methylated PCa|NTDMRs chr7 25934526 25935252 0.001501564 22.73389356 Hyper-methylatedPCa|NT DMRs chr7 26192189 26216465 2.32E−07 21.98901099 Hyper-methylatedPCa|NT DMRs chr7 27127534 27135348 1.38E−12 35.56059113 Hyper-methylatedPCa|NT DMRs chr7 27141679 27143236 3.93E−11 49.08095238 Hyper-methylatedPCa|NT DMRs chr7 27169137 27170067 1.33E−08 −22.6457672 Hypo-methylatedPCa|NT DMRs chr7 27191524 27195204 1.33E−07 21.14713065 Hyper-methylatedPCa|NT DMRs chr7 27214660 27215710 4.08E−15 −37.0315735 Hypo-methylatedPCa|NT DMRs chr7 27242048 27265523 1.06E−31 37.02774943 Hyper-methylatedPCa|NT DMRs chr7 28887427 28887706 2.79E−05 −20.33333333 Hypo-methylatedPCa|NT DMRs chr7 28995117 28995552 1.43E−05 23.96518883 Hyper-methylatedPCa|NT DMRs chr7 30028084 30028297 0.000205174 44.95535714Hyper-methylated PCa|NT DMRs chr7 31037912 31070475 4.57E−06−25.77063492 Hypo-methylated PCa|NT DMRs chr7 31100405 311167890.000570576 −24.60695971 Hypo-methylated PCa|NT DMRs chr7 3112519931174196 0.002225326 −25.60340136 Hypo-methylated PCa|NT DMRs chr732306595 32335481 1.52E−07 −42.74489796 Hypo-methylated PCa|NT DMRs chr732347627 32437622 3.15E−05 −28.69440994 Hypo-methylated PCa|NT DMRs chr732482461 32518978 3.13E−07 −27.25972222 Hypo-methylated PCa|NT DMRs chr732981742 32982455 2.06E−16 23.23971088 Hyper-methylated PCa|NT DMRs chr733871558 33871895 0.003871035 −44.37142857 Hypo-methylated PCa|NT DMRschr7 33943681 33944041 5.04E−06 20.76022409 Hyper-methylated PCa|NT DMRschr7 34444720 34938659 4.62E−14 −33.13625541 Hypo-methylated PCa|NT DMRschr7 35340373 35403073 0.00064571  −37.22993197 Hypo-methylated PCa|NTDMRs chr7 36007041 36007467 2.24E−06 30.45303777 Hyper-methylated PCa|NTDMRs chr7 36011125 36018066 4.61E−13 32.0223518 Hyper-methylated PCa|NTDMRs chr7 36564256 36584280 0.000481535 −36.06349206 Hypo-methylatedPCa|NT DMRs chr7 36687754 36838381 2.19E−08 −24.1377551 Hypo-methylatedPCa|NT DMRs chr7 37038702 37129765 0.00064571  −28.95442177Hypo-methylated PCa|NT DMRs chr7 37231246 37250947 0.003314163−25.18809524 Hypo-methylated PCa|NT DMRs chr7 37392953 373930500.001969641 43.08843537 Hyper-methylated PCa|NT DMRs chr7 3835110338370875 0.006207271 24.76309524 Hyper-methylated PCa|NT DMRs chr738449115 38669647 1.22E−07 −33.12797619 Hypo-methylated PCa|NT DMRs chr739164189 39227160 0.001098825 −29.41876751 Hypo-methylated PCa|NT DMRschr7 39273162 39443222 1.76E−12 −32.17777778 Hypo-methylated PCa|NT DMRschr7 39497898 39514914 6.42E−05 −46.49100529 Hypo-methylated PCa|NT DMRschr7 39579070 39586319 0.003391914 −27.2037037 Hypo-methylated PCa|NTDMRs chr7 44315769 44315996 0.003622801 34.96428571 Hyper-methylatedPCa|NT DMRs chr7 44607827 44613004 0.003510453 −20.84897959Hypo-methylated PCa|NT DMRs chr7 45068084 45068309 0.00020517450.33154762 Hyper-methylated PCa|NT DMRs chr7 45229350 45233748 1.15E−05−25.54547619 Hypo-methylated PCa|NT DMRs chr7 45300230 45429858 5.02E−12−34.73346561 Hypo-methylated PCa|NT DMRs chr7 45438807 45553939 3.61E−11−32.90686275 Hypo-methylated PCa|NT DMRs chr7 45597605 456062840.000836132 −22.44708995 Hypo-methylated PCa|NT DMRs chr7 4596123945961563 2.18E−06 21.72481203 Hyper-methylated PCa|NT DMRs chr7 4600237846495473 4.55E−10 −29.56834734 Hypo-methylated PCa|NT DMRs chr7 4715444347165537 0.00064571  −37.27891156 Hypo-methylated PCa|NT DMRs chr747231371 47262951 0.003464153 −26.63246753 Hypo-methylated PCa|NT DMRschr7 47367493 47368403 0.000320955 −21.10582011 Hypo-methylated PCa|NTDMRs chr7 47616221 47616717 0.000840726 −26.02910053 Hypo-methylatedPCa|NT DMRs chr7 47620545 47620828 0.000260936 31.88571429Hyper-methylated PCa|NT DMRs chr7 47621795 47622199 0.00102122920.5995671 Hyper-methylated PCa|NT DMRs chr7 47709393 477096040.000205174 52.36428571 Hyper-methylated PCa|NT DMRs chr7 4778692547803215 0.006589535 −26.35047619 Hypo-methylated PCa|NT DMRs chr748031355 48031800 1.27E−08 34.22619048 Hyper-methylated PCa|NT DMRs chr748047274 48049568 0.004095673 −29.31746032 Hypo-methylated PCa|NT DMRschr7 48075936 48075985 0.001111028 21.13227513 Hyper-methylated PCa|NTDMRs chr7 48083649 48086861 9.43E−05 −26.21758242 Hypo-methylated PCa|NTDMRs chr7 48331271 48882713 8.64E−21 −32.35232558 Hypo-methylated PCa|NTDMRs chr7 49814718 49814795 0.000116533 25.83116883 Hyper-methylatedPCa|NT DMRs chr7 49843083 50016555 4.82E−06 −33.85267857 Hypo-methylatedPCa|NT DMRs chr7 50198161 50198986 8.30E−07 −32.42380952 Hypo-methylatedPCa|NT DMRs chr7 50221938 50226954 0.001969641 −34.31984127Hypo-methylated PCa|NT DMRs chr7 50293957 50343250 1.27E−05 −40.95396825Hypo-methylated PCa|NT DMRs chr7 50417791 50417858 0.001969641−29.57936508 Hypo-methylated PCa|NT DMRs chr7 50431031 50468270 1.37E−09−39.34850088 Hypo-methylated PCa|NT DMRs chr7 52155818 521558780.000205174 42.21428571 Hyper-methylated PCa|NT DMRs chr7 5246781652528725 0.002094   −27.95992063 Hypo-methylated PCa|NT DMRs chr753172302 53234254 6.42E−05 −30.12698413 Hypo-methylated PCa|NT DMRs chr753286853 53287127 5.96E−09 22.51465201 Hyper-methylated PCa|NT DMRs chr753453173 53701286 6.09E−13 −27.76734694 Hypo-methylated PCa|NT DMRs chr753861390 54511977 2.98E−22 −32.33258145 Hypo-methylated PCa|NT DMRs chr754659215 54732133 0.001982559 −21.03174603 Hypo-methylated PCa|NT DMRschr7 54765896 54798598 3.60E−06 −26.52248677 Hypo-methylated PCa|NT DMRschr7 54901215 54901260 0.00064571  −57.92789116 Hypo-methylated PCa|NTDMRs chr7 55072375 55086430 4.51E−07 23.54591837 Hyper-methylated PCa|NTDMRs chr7 55735259 55799334 2.28E−06 −25.11813187 Hypo-methylated PCa|NTDMRs chr7 55840928 55849758 0.005772882 −24.24444444 Hypo-methylatedPCa|NT DMRs chr7 55885947 55936017 7.61E−07 −28.02683983 Hypo-methylatedPCa|NT DMRs chr7 56033317 56046059 2.52E−05 −37.18431373 Hypo-methylatedPCa|NT DMRs chr7 56120370 56127424 0.003622801 −43.57142857Hypo-methylated PCa|NT DMRs chr7 56147132 56147286 0.00064571 −48.5952381 Hypo-methylated PCa|NT DMRs chr7 56159429 561637150.004540278 −26.29285714 Hypo-methylated PCa|NT DMRs chr7 5619364356231315 0.000392715 −32.55142857 Hypo-methylated PCa|NT DMRs chr762532592 62573974 7.46E−07 −28.23864469 Hypo-methylated PCa|NT DMRs chr763438308 63459428 9.13E−06 −31.39724311 Hypo-methylated PCa|NT DMRs chr764019216 64020792 0.005968871 −26.79904762 Hypo-methylated PCa|NT DMRschr7 64029966 64030939 4.83E−10 24.6031746 Hyper-methylated PCa|NT DMRschr7 64316961 64330130 7.34E−05 −25.2552381 Hypo-methylated PCa|NT DMRschr7 64349528 64350017 1.84E−14 34.58228128 Hyper-methylated PCa|NT DMRschr7 65337399 65337460 0.003871035 −22.32142857 Hypo-methylated PCa|NTDMRs chr7 65508863 65509219 2.15E−07 29.30204082 Hyper-methylated PCa|NTDMRs chr7 65967694 65968124 6.42E−05 −24.66402116 Hypo-methylated PCa|NTDMRs chr7 65968275 65969422 0.000575877 −29.34848485 Hypo-methylatedPCa|NT DMRs chr7 66829609 66829834 1.99E−07 25.38877551 Hyper-methylatedPCa|NT DMRs chr7 66888256 66888455 0.005968871 −34.03238095Hypo-methylated PCa|NT DMRs chr7 66958369 66958662 0.00179283 −40.12857143 Hypo-methylated PCa|NT DMRs chr7 68887842 688879110.005968871 −52.62857143 Hypo-methylated PCa|NT DMRs chr7 7125681171267196 0.002437742 −29.96455026 Hypo-methylated PCa|NT DMRs chr771800532 71801133 3.56E−11 20.56692407 Hyper-methylated PCa|NT DMRs chr772419050 72419443 0.00641359  −23.21587302 Hypo-methylated PCa|NT DMRschr7 72838296 72838812 1.35E−07 30.43061224 Hyper-methylated PCa|NT DMRschr7 73072051 73081648 0.00399983  −20.44987469 Hypo-methylated PCa|NTDMRs chr7 73083583 73085702 0.000255063 24.15610119 Hyper-methylatedPCa|NT DMRs chr7 73155879 73161189 3.00E−06 −29.92624585 Hypo-methylatedPCa|NT DMRs chr7 73236823 73237244 0.000117699 −56.70995671Hypo-methylated PCa|NT DMRs chr7 73244523 73247798 1.08E−14 −55.64989177Hypo-methylated PCa|NT DMRs chr7 73300934 73305474 0.00103937835.61611722 Hyper-methylated PCa|NT DMRs chr7 73305581 733057390.005968871 −31.57428571 Hypo-methylated PCa|NT DMRs chr7 7333107273331269 0.005968871 −49.22857143 Hypo-methylated PCa|NT DMRs chr773437361 73438920 4.61E−05 −32.75555556 Hypo-methylated PCa|NT DMRs chr773442880 73444203 0.000822388 20.62337662 Hyper-methylated PCa|NT DMRschr7 73457452 73457743 6.42E−05 −50.6026455 Hypo-methylated PCa|NT DMRschr7 73476300 73476511 0.003448944 −27.2244898 Hypo-methylated PCa|NTDMRs chr7 73497616 73497790 0.002585277 20.85714286 Hyper-methylatedPCa|NT DMRs chr7 73498750 73498982 5.12E−06 25.57482993 Hyper-methylatedPCa|NT DMRs chr7 73507826 73509173 6.33E−13 45.64367015 Hyper-methylatedPCa|NT DMRs chr7 73720490 73721657 2.39E−09 33.46781609 Hyper-methylatedPCa|NT DMRs chr7 73818559 73819866 0.003159484 −24.6647619Hypo-methylated PCa|NT DMRs chr7 73889890 73890169 0.007560755−24.57857143 Hypo-methylated PCa|NT DMRs chr7 73894831 73895072 5.19E−0733.61904762 Hyper-methylated PCa|NT DMRs chr7 73994502 739945680.005968871 −28.17142857 Hypo-methylated PCa|NT DMRs chr7 7407477474075634 1.57E−06 39.29161905 Hyper-methylated PCa|NT DMRs chr7 7407573374086834 0.006225823 −20.26233766 Hypo-methylated PCa|NT DMRs chr775045443 75046477 0.00179283  −25.88988095 Hypo-methylated PCa|NT DMRschr7 75615224 75615978 0.000123553 −28.88235294 Hypo-methylated PCa|NTDMRs chr7 75687295 75687366 0.00064571  −55.30612245 Hypo-methylatedPCa|NT DMRs chr7 75779637 75779924 7.94E−10 23.75333333 Hyper-methylatedPCa|NT DMRs chr7 77354038 77354284 0.00064571  25.54761905Hyper-methylated PCa|NT DMRs chr7 77669600 77669964 0.00170940331.54464286 Hyper-methylated PCa|NT DMRs chr7 78498162 79031908 1.42E−12−34.75889724 Hypo-methylated PCa|NT DMRs chr7 79114858 79368969 3.61E−13−35.9025641 Hypo-methylated PCa|NT DMRs chr7 81168472 81305783 1.67E−07−24.9890873 Hypo-methylated PCa|NT DMRs chr7 81422971 81440915 6.42E−05−30.40952381 Hypo-methylated PCa|NT DMRs chr7 83368628 83783731 1.12E−16−24.01720969 Hypo-methylated PCa|NT DMRs chr7 83909556 839384560.000208485 −24.07619048 Hypo-methylated PCa|NT DMRs chr7 8522100885395494 0.001344447 −35.79464286 Hypo-methylated PCa|NT DMRs chr785472847 85579521 4.96E−06 −22.02747253 Hypo-methylated PCa|NT DMRs chr785602117 86268957 4.45E−15 −34.39265873 Hypo-methylated PCa|NT DMRs chr792672831 92672988 1.97E−05 24.98571429 Hyper-methylated PCa|NT DMRs chr796635908 96636917 3.22E−10 33.74111498 Hyper-methylated PCa|NT DMRs chr796646327 96652464 7.52E−12 36.78391734 Hyper-methylated PCa|NT DMRs chr796654782 96656815 0.00083792  28.97029478 Hyper-methylated PCa|NT DMRschr7 97498323 97498568 0.008482405 23.81904762 Hyper-methylated PCa|NTDMRs chr7 97663616 97663883 0.003448944 −24.47346939 Hypo-methylatedPCa|NT DMRs chr7 97744982 97755838 0.002416251 28.13333333Hyper-methylated PCa|NT DMRs chr7 97795322 97795441 0.000481535−23.26984127 Hypo-methylated PCa|NT DMRs chr7 97839946 97840075 8.31E−0725.76190476 Hyper-methylated PCa|NT DMRs chr7 97840799 97847454 8.66E−09−25.60642857 Hypo-methylated PCa|NT DMRs chr7 97852407 978541860.001391421 −35.4952381 Hypo-methylated PCa|NT DMRs chr7 9791170497914995 0.008073155 −22.7491342 Hypo-methylated PCa|NT DMRs chr797920380 97920911 3.05E−06 −23.67032967 Hypo-methylated PCa|NT DMRs chr797921626 97927265 0.000158614 −28.38452381 Hypo-methylated PCa|NT DMRschr7 98245716 98245858 0.008345196 24.75 Hyper-methylated PCa|NT DMRschr7 98258710 98287247 0.000440265 −25.64583333 Hypo-methylated PCa|NTDMRs chr7 98424445 98424689 6.42E−05 −26.85714286 Hypo-methylated PCa|NTDMRs chr7 98971627 98972198 6.00E−08 26.71868132 Hyper-methylated PCa|NTDMRs chr7 99156074 99156869 3.97E−23 22.7885034 Hyper-methylated PCa|NTDMRs chr7 99165661 99166035 0.00064571  −28.18367347 Hypo-methylatedPCa|NT DMRs chr7 99177356 99178048 1.65E−05 28.71170635 Hyper-methylatedPCa|NT DMRs chr7 99204325 99208815 0.005968871 −35.76190476Hypo-methylated PCa|NT DMRs chr7 99589389 99596385 0.00902626929.07097506 Hyper-methylated PCa|NT DMRs chr7 99817556 99820023 7.40E−1124.78277311 Hyper-methylated PCa|NT DMRs chr7 100028261 1000289794.33E−05 23.4273183 Hyper-methylated PCa|NT DMRs chr7 100091312100091715 9.97E−15 28.99415584 Hyper-methylated PCa|NT DMRs chr7100180073 100180129 0.001969641 −41.22619048 Hypo-methylated PCa|NT DMRschr7 100422720 100423018 0.00064571  −39.9122449 Hypo-methylated PCa|NTDMRs chr7 100426084 100427131 0.000112123 42.11071429 Hyper-methylatedPCa|NT DMRs chr7 100461849 100463658 0.002487133 29.03809524Hyper-methylated PCa|NT DMRs chr7 100464553 100466260 1.78E−1033.13746867 Hyper-methylated PCa|NT DMRs chr7 100488589 1004890311.72E−05 34.85136054 Hyper-methylated PCa|NT DMRs chr7 100550991100555206 0.003464153 −22.88311688 Hypo-methylated PCa|NT DMRs chr7100659891 100660212 0.004553481 24.66666667 Hyper-methylated PCa|NT DMRschr7 100867268 100867468 0.005968871 22.57142857 Hyper-methylated PCa|NTDMRs chr7 100872377 100876205 1.05E−10 −46.25660377 Hypo-methylatedPCa|NT DMRs chr7 100879314 100882709 6.29E−12 32.37727273Hyper-methylated PCa|NT DMRs chr7 100943137 100943778 6.49E−0520.76428571 Hyper-methylated PCa|NT DMRs chr7 100946052 1009469168.30E−11 33.60720093 Hyper-methylated PCa|NT DMRs chr7 101261954101262523 6.42E−05 −31.79259259 Hypo-methylated PCa|NT DMRs chr7101273855 101274191 0.002097193 38.57482993 Hyper-methylated PCa|NT DMRschr7 101280380 101288502 0.00046209  −35.28571429 Hypo-methylated PCa|NTDMRs chr7 101335369 101335742 0.001013662 31.64795918 Hyper-methylatedPCa|NT DMRs chr7 101342277 101351052 8.81E−07 −37.51183673Hypo-methylated PCa|NT DMRs chr7 101360530 101362081 2.50E−0635.81989796 Hyper-methylated PCa|NT DMRs chr7 101391074 1013914230.001471804 −28.27142857 Hypo-methylated PCa|NT DMRs chr7 101543446101544937 0.002562908 −53.30952381 Hypo-methylated PCa|NT DMRs chr7101571203 101575580 0.008581782 28.22619048 Hyper-methylated PCa|NT DMRschr7 101578022 101579991 6.20E−05 −25.66857143 Hypo-methylated PCa|NTDMRs chr7 101584333 101584417 0.008482405 −35.28571429 Hypo-methylatedPCa|NT DMRs chr7 101958901 101962182 1.36E−08 20.38534226Hyper-methylated PCa|NT DMRs chr7 102066109 102066575 1.01E−0852.66450216 Hyper-methylated PCa|NT DMRs chr7 102081660 1020859390.002822916 27.01964286 Hyper-methylated PCa|NT DMRs chr7 105293408105294359 0.005968871 −35.75714286 Hypo-methylated PCa|NT DMRs chr7105319161 105319858 3.06E−08 32.60559006 Hyper-methylated PCa|NT DMRschr7 105517812 105517955 0.002826041 29.95918367 Hyper-methylated PCa|NTDMRs chr7 106673369 106682188 0.000570576 30.44338624 Hyper-methylatedPCa|NT DMRs chr7 107518437 107526769 0.00025637  −24.44166667Hypo-methylated PCa|NT DMRs chr7 107641801 107642842 1.78E−0626.17142857 Hyper-methylated PCa|NT DMRs chr7 108573874 1094352425.49E−08 −29.01035197 Hypo-methylated PCa|NT DMRs chr7 113505091113718634 8.88E−08 −20.85102041 Hypo-methylated PCa|NT DMRs chr7117410909 117498280 5.94E−06 −31.84415584 Hypo-methylated PCa|NT DMRschr7 117854304 117854944 0.000233379 24.02857143 Hyper-methylated PCa|NTDMRs chr7 118600016 118725787 6.99E−05 −26.67326007 Hypo-methylatedPCa|NT DMRs chr7 118953370 119591869 2.07E−13 −27.33095238Hypo-methylated PCa|NT DMRs chr7 119623727 119900893 1.30E−09−33.15190476 Hypo-methylated PCa|NT DMRs chr7 124765830 1249803141.14E−06 −23.40385488 Hypo-methylated PCa|NT DMRs chr7 127912088127912382 2.13E−06 28.63428571 Hyper-methylated PCa|NT DMRs chr7128046447 128046586 0.001083007 −24.2952381 Hypo-methylated PCa|NT DMRschr7 128048705 128049001 0.000205174 41.39880952 Hyper-methylated PCa|NTDMRs chr7 128430418 128431143 9.04E−05 24.03753501 Hyper-methylatedPCa|NT DMRs chr7 128470351 128474036 1.56E−18 28.43789683Hyper-methylated PCa|NT DMRs chr7 128509912 128510319 2.88E−0525.61759834 Hyper-methylated PCa|NT DMRs chr7 128519584 1285209366.22E−05 −42.14863946 Hypo-methylated PCa|NT DMRs chr7 128573479128573579 0.000205174 47.86904762 Hyper-methylated PCa|NT DMRs chr7128578726 128581589 2.07E−05 38.11721612 Hyper-methylated PCa|NT DMRschr7 128809044 128809288 7.00E−10 35.59831029 Hyper-methylated PCa|NTDMRs chr7 128851432 128852053 0.009106413 24.16269841 Hyper-methylatedPCa|NT DMRs chr7 129780773 129781240 0.001731883 26.65404762Hyper-methylated PCa|NT DMRs chr7 129794322 129794625 0.001419801−39.43095238 Hypo-methylated PCa|NT DMRs chr7 129917732 1299457169.63E−06 −28.29795918 Hypo-methylated PCa|NT DMRs chr7 129986609129990875 0.001789867 −23.76455026 Hypo-methylated PCa|NT DMRs chr7130010730 130019806 2.49E−05 −31.99447005 Hypo-methylated PCa|NT DMRschr7 130127778 130132823 1.59E−27 21.96573661 Hyper-methylated PCa|NTDMRs chr7 130369743 130392873 0.002215138 −22.97472527 Hypo-methylatedPCa|NT DMRs chr7 130432349 130490560 0.00064571  −27.92857143Hypo-methylated PCa|NT DMRs chr7 130586419 130589355 0.004553481−26.67037037 Hypo-methylated PCa|NT DMRs chr7 131192644 1311929140.001888566 −21.14232804 Hypo-methylated PCa|NT DMRs chr7 131242618131243006 1.69E−06 30.16946779 Hyper-methylated PCa|NT DMRs chr7131308045 131308107 0.003622801 24.32936508 Hyper-methylated PCa|NT DMRschr7 131350332 131373284 7.57E−05 −32.67857143 Hypo-methylated PCa|NTDMRs chr7 131514718 131515085 8.49E−05 21.51555556 Hyper-methylatedPCa|NT DMRs chr7 132160221 132160827 0.000243521 27.2961039Hyper-methylated PCa|NT DMRs chr7 134236689 134237201 0.003448944−20.65170068 Hypo-methylated PCa|NT DMRs chr7 134851193 1348515920.00064571  42.98367347 Hyper-methylated PCa|NT DMRs chr7 137531886137532401 7.66E−13 25.55493612 Hyper-methylated PCa|NT DMRs chr7137668416 137668618 0.008482405 −49.16666667 Hypo-methylated PCa|NT DMRschr7 138407351 138424610 0.002097193 −20.37891156 Hypo-methylated PCa|NTDMRs chr7 138761042 138761120 0.004095673 −45.57142857 Hypo-methylatedPCa|NT DMRs chr7 138773705 138789703 0.006668079 22.41190476Hyper-methylated PCa|NT DMRs chr7 140135272 140135575 1.18E−0833.35515873 Hyper-methylated PCa|NT DMRs chr7 140212417 1402198410.00095173  −23.04027778 Hypo-methylated PCa|NT DMRs chr7 141589733141720786 0.000145366 −25.14965986 Hypo-methylated PCa|NT DMRs chr7141849501 142012611 6.93E−06 −30.46209524 Hypo-methylated PCa|NT DMRschr7 142237672 142332431 1.52E−07 −27.58163265 Hypo-methylated PCa|NTDMRs chr7 143042512 143042867 1.06E−06 24.44285714 Hyper-methylatedPCa|NT DMRs chr7 143079114 143079495 2.38E−07 31.69480519Hyper-methylated PCa|NT DMRs chr7 143110984 143111353 0.00551366121.2755102 Hyper-methylated PCa|NT DMRs chr7 144565758 1447130510.001969641 −30.5 Hypo-methylated PCa|NT DMRs chr7 145481156 1454817680.003622801 −31.31746032 Hypo-methylated PCa|NT DMRs chr7 148198549148308634 0.00338426  −24.97104762 Hypo-methylated PCa|NT DMRs chr7149095044 149095100 0.009106413 26.02380952 Hyper-methylated PCa|NT DMRschr7 149411257 149411705 0.001182824 24.26632653 Hyper-methylated PCa|NTDMRs chr7 149412141 149412486 1.72E−07 24.44444444 Hyper-methylatedPCa|NT DMRs chr7 149566838 149567085 0.005968871 57.24285714Hyper-methylated PCa|NT DMRs chr7 149916642 149917350 0.00015912625.69607843 Hyper-methylated PCa|NT DMRs chr7 150069281 1500699467.82E−16 −31.7047619 Hypo-methylated PCa|NT DMRs chr7 150118633150140064 0.005030552 −26.05208333 Hypo-methylated PCa|NT DMRs chr7150328663 150329487 0.000836132 54.07407407 Hyper-methylated PCa|NT DMRschr7 150692222 150695535 3.23E−07 34.98761905 Hyper-methylated PCa|NTDMRs chr7 150773386 150774524 0.004149771 −24.3010989 Hypo-methylatedPCa|NT DMRs chr7 150890349 150890467 0.000205174 −30.5922619Hypo-methylated PCa|NT DMRs chr7 150951963 150954795 1.08E−07−31.85514593 Hypo-methylated PCa|NT DMRs chr7 151077969 1510780990.003622801 37.41428571 Hyper-methylated PCa|NT DMRs chr7 151437844151442405 0.008083098 28.18507937 Hyper-methylated PCa|NT DMRs chr7151516235 151517272 0.005513661 −45.47482993 Hypo-methylated PCa|NT DMRschr7 151535841 151536655 3.15E−06 57.75502646 Hyper-methylated PCa|NTDMRs chr7 152210265 152210334 0.000205174 48.89285714 Hyper-methylatedPCa|NT DMRs chr7 152559079 152559308 0.00064571  30.20068027Hyper-methylated PCa|NT DMRs chr7 152591316 152591405 0.000205174−36.17261905 Hypo-methylated PCa|NT DMRs chr7 154705890 1547060400.000210841 34.6 Hyper-methylated PCa|NT DMRs chr7 154813067 1548593453.95E−06 −27.51047619 Hypo-methylated PCa|NT DMRs chr7 154863874154879336 0.00064571  −27.77210884 Hypo-methylated PCa|NT DMRs chr7154899588 154902631 9.81E−07 −34.54634921 Hypo-methylated PCa|NT DMRschr7 154923361 154958943 8.28E−07 −30.12408964 Hypo-methylated PCa|NTDMRs chr7 154961253 154981577 0.00068166  −25.80416667 Hypo-methylatedPCa|NT DMRs chr7 154986754 154991510 1.67E−06 −26.50125313Hypo-methylated PCa|NT DMRs chr7 154993934 155006511 0.000149911−20.96439909 Hypo-methylated PCa|NT DMRs chr7 155039686 1550496731.02E−05 −29.40642857 Hypo-methylated PCa|NT DMRs chr7 155058099155080113 2.57E−12 −24.35019305 Hypo-methylated PCa|NT DMRs chr7155307843 155318299 1.67E−05 −20.23333333 Hypo-methylated PCa|NT DMRschr7 155386238 155386991 0.009924186 25.23809524 Hyper-methylated PCa|NTDMRs chr7 155556567 155556757 1.69E−06 52.38655462 Hyper-methylatedPCa|NT DMRs chr7 155579930 155580536 1.21E−17 21.74123989Hyper-methylated PCa|NT DMRs chr7 155598430 155599414 1.98E−0933.88637874 Hyper-methylated PCa|NT DMRs chr7 155606684 1556072300.000170278 34.01984127 Hyper-methylated PCa|NT DMRs chr7 155636891155637294 0.000783791 −34.4 Hypo-methylated PCa|NT DMRs chr7 156255240156255292 0.001969641 −40.71428571 Hypo-methylated PCa|NT DMRs chr7156696702 156700085 0.007959104 −34.6122449 Hypo-methylated PCa|NT DMRschr7 156716094 156722985 0.009924186 24.65555556 Hyper-methylated PCa|NTDMRs chr7 156735267 156735665 1.54E−06 24.73854875 Hyper-methylatedPCa|NT DMRs chr7 156786078 156786279 0.000783791 22.62857143Hyper-methylated PCa|NT DMRs chr7 156800870 156802228 1.42E−0525.81031746 Hyper-methylated PCa|NT DMRs chr7 156805387 1568107561.64E−08 24.71848739 Hyper-methylated PCa|NT DMRs chr7 156814372156826180 1.15E−06 21.26862027 Hyper-methylated PCa|NT DMRs chr7156917419 156917926 1.29E−05 −32.13184524 Hypo-methylated PCa|NT DMRschr7 157078970 157082281 0.009924186 −34.69312169 Hypo-methylated PCa|NTDMRs chr7 157090015 157093261 0.000516919 25.48263305 Hyper-methylatedPCa|NT DMRs chr7 157261528 157263081 2.02E−10 −23.44690983Hypo-methylated PCa|NT DMRs chr7 157288249 157291070 2.02E−05−25.55132275 Hypo-methylated PCa|NT DMRs chr7 157306855 1573070510.000974795 −33.4702381 Hypo-methylated PCa|NT DMRs chr7 157315700157320784 1.57E−06 −23.75565476 Hypo-methylated PCa|NT DMRs chr7157378077 157378560 2.32E−06 39.78711485 Hyper-methylated PCa|NT DMRschr7 157405582 157406762 6.77E−16 33.40800866 Hyper-methylated PCa|NTDMRs chr7 157461082 157461525 0.000969909 36.485 Hyper-methylated PCa|NTDMRs chr7 157648636 157648754 0.003391914 29.50846561 Hyper-methylatedPCa|NT DMRs chr7 157668107 157668187 0.005968871 40.02857143Hyper-methylated PCa|NT DMRs chr7 157793319 157795183 2.98E−07−37.55824176 Hypo-methylated PCa|NT DMRs chr7 157820956 1578212310.003448944 −28.91836735 Hypo-methylated PCa|NT DMRs chr7 158030503158030841 4.50E−09 −32.18897243 Hypo-methylated PCa|NT DMRs chr7158110582 158111273 1.98E−08 36.19177489 Hyper-methylated PCa|NT DMRschr7 158201160 158201414 0.001969641 53.41666667 Hyper-methylated PCa|NTDMRs chr7 158221366 158221418 0.001969641 48.57142857 Hyper-methylatedPCa|NT DMRs chr8 157149 157227 0.003622801 −23.09126984 Hypo-methylatedPCa|NT DMRs chr8 335341 335523 0.000396159 −42.38571429 Hypo-methylatedPCa|NT DMRs chr8 495872 496327 0.008518096 22.46825397 Hyper-methylatedPCa|NT DMRs chr8 523093 523250 0.00064571  −58.76326531 Hypo-methylatedPCa|NT DMRs chr8 635022 637739 4.47E−08 −34.59032738 Hypo-methylatedPCa|NT DMRs chr8 644216 644850 0.000512756 −49.7952381 Hypo-methylatedPCa|NT DMRs chr8 672007 675055 0.002285154 21.10714286 Hyper-methylatedPCa|NT DMRs chr8 748423 754477 0.003093471 −33.20793651 Hypo-methylatedPCa|NT DMRs chr8 898192 898681 5.85E−07 51.89501134 Hyper-methylatedPCa|NT DMRs chr8 899474 900191 6.58E−08 38.90828157 Hyper-methylatedPCa|NT DMRs chr8 1308896 1311552 0.002950526 22.93557423Hyper-methylated PCa|NT DMRs chr8 1365050 1365223 1.76E−06 28.08373016Hyper-methylated PCa|NT DMRs chr8 1728651 1729449 4.38E−05 −25.62559524Hypo-methylated PCa|NT DMRs chr8 1803030 1805181 9.49E−05 23.93479853Hyper-methylated PCa|NT DMRs chr8 1807321 1807799 0.002097193−47.42176871 Hypo-methylated PCa|NT DMRs chr8 1810232 1810429 3.66E−05−30.8 Hypo-methylated PCa|NT DMRs chr8 1894575 1896172 0.000149336−38.43277311 Hypo-methylated PCa|NT DMRs chr8 1950305 1954120 2.77E−1430.27138856 Hyper-methylated PCa|NT DMRs chr8 1969030 19719980.00013578  20.95145503 Hyper-methylated PCa|NT DMRs chr8 20396492040225 1.16E−05 −24.63613445 Hypo-methylated PCa|NT DMRs chr8 20487422049292 8.17E−05 −20.66233766 Hypo-methylated PCa|NT DMRs chr8 21917692210544 1.30E−09 −33.79047619 Hypo-methylated PCa|NT DMRs chr8 22227612243000 2.12E−05 −29.02571429 Hypo-methylated PCa|NT DMRs chr8 22690602403929 2.10E−14 −37.02970522 Hypo-methylated PCa|NT DMRs chr8 26074302609669 0.003093471 −26.00952381 Hypo-methylated PCa|NT DMRs chr86631261 6633060 0.001254235 −40.56153846 Hypo-methylated PCa|NT DMRschr8 6758409 6761867 0.007959104 −37.78231293 Hypo-methylated PCa|NTDMRs chr8 7340396 7641383 0.003223657 −20.95686275 Hypo-methylatedPCa|NT DMRs chr8 8560333 8560812 0.000456684 30.17896825Hyper-methylated PCa|NT DMRs chr8 9107225 9136077 1.37E−06 −25.60975057Hypo-methylated PCa|NT DMRs chr8 9194614 9222629 0.008581782−20.54880952 Hypo-methylated PCa|NT DMRs chr8 9705662 9754896 6.50E−07−26.08178054 Hypo-methylated PCa|NT DMRs chr8 9762687 9762892 7.61E−0720.81168831 Hyper-methylated PCa|NT DMRs chr8 9764450 9764994 1.97E−0521.13311688 Hyper-methylated PCa|NT DMRs chr8 9770284 9855269 3.62E−07−22.70229592 Hypo-methylated PCa|NT DMRs chr8 10282184 102824160.001969641 −35.87142857 Hypo-methylated PCa|NT DMRs chr8 1039341810393469 0.005513661 −25.56428571 Hypo-methylated PCa|NT DMRs chr810404809 10405127 0.001969641 31.83260073 Hyper-methylated PCa|NT DMRschr8 10448867 10450166 0.00068166  30.43154762 Hyper-methylated PCa|NTDMRs chr8 10568487 10568843 0.000377317 41.29761905 Hyper-methylatedPCa|NT DMRs chr8 10573606 10574501 9.51E−10 33.43645833 Hyper-methylatedPCa|NT DMRs chr8 10911919 10913565 0.004266047 20.51948052Hyper-methylated PCa|NT DMRs chr8 11323538 11323621 0.00023371 −20.58333333 Hypo-methylated PCa|NT DMRs chr8 11470739 11471216 2.91E−0727.74627976 Hyper-methylated PCa|NT DMRs chr8 11508100 115087330.000260936 −45.73714286 Hypo-methylated PCa|NT DMRs chr8 1165340111653492 0.000205174 −45.51904762 Hypo-methylated PCa|NT DMRs chr811710911 11711186 0.003871035 −38.53571429 Hypo-methylated PCa|NT DMRschr8 11735071 11735436 0.001969641 48.00396825 Hyper-methylated PCa|NTDMRs chr8 11743803 11743915 0.001969641 41.32380952 Hyper-methylatedPCa|NT DMRs chr8 11762895 11763898 0.003448944 −24.71088435Hypo-methylated PCa|NT DMRs chr8 14424399 14532548 3.31E−10 −35.33395445Hypo-methylated PCa|NT DMRs chr8 14640664 15042204 1.31E−11 −33.06517857Hypo-methylated PCa|NT DMRs chr8 15125433 15231562 2.01E−07 −37.7047619Hypo-methylated PCa|NT DMRs chr8 15263553 15263737 0.005968871−44.94285714 Hypo-methylated PCa|NT DMRs chr8 15782085 15903541 8.96E−05−26.41120448 Hypo-methylated PCa|NT DMRs chr8 16669253 166875160.000149331 −32.20562771 Hypo-methylated PCa|NT DMRs chr8 1710579217106080 0.007425114 −26.64285714 Hypo-methylated PCa|NT DMRs chr817270930 17271329 6.81E−12 21.39880952 Hyper-methylated PCa|NT DMRs chr817533391 17533670 0.005968871 −23.14666667 Hypo-methylated PCa|NT DMRschr8 17954994 17955260 0.000974795 −55.31845238 Hypo-methylated PCa|NTDMRs chr8 18243948 18244094 0.001969641 −23.04081633 Hypo-methylatedPCa|NT DMRs chr8 18244312 18257704 2.55E−07 27.13801843 Hyper-methylatedPCa|NT DMRs chr8 18871661 18872113 2.68E−11 30.63835264 Hyper-methylatedPCa|NT DMRs chr8 20160002 20160842 0.000226106 28.1959707Hyper-methylated PCa|NT DMRs chr8 20303498 20305063 6.42E−05−24.68042328 Hypo-methylated PCa|NT DMRs chr8 20952800 209530160.005968871 −51.80952381 Hypo-methylated PCa|NT DMRs chr8 2106759021067765 0.000205174 42.3452381 Hyper-methylated PCa|NT DMRs chr821263846 21275095 0.001969641 −39.75170068 Hypo-methylated PCa|NT DMRschr8 21614351 21626112 0.000815653 −22.51772487 Hypo-methylated PCa|NTDMRs chr8 21764141 21767204 3.91E−05 −39.72063492 Hypo-methylated PCa|NTDMRs chr8 21769239 21770745 0.000198783 34.74175824 Hyper-methylatedPCa|NT DMRs chr8 21900543 21906062 0.000149006 22.24015152Hyper-methylated PCa|NT DMRs chr8 21944035 21944339 6.94E−06 41.34920635Hyper-methylated PCa|NT DMRs chr8 21988910 21990525 0.000326385−22.20337302 Hypo-methylated PCa|NT DMRs chr8 21996161 219973880.000139576 25.76260504 Hyper-methylated PCa|NT DMRs chr8 2202149322021814 0.0014802  20.23933747 Hyper-methylated PCa|NT DMRs chr822429857 22436387 0.004556523 23.52857143 Hyper-methylated PCa|NT DMRschr8 22437343 22438902 0.002055421 33.99383754 Hyper-methylated PCa|NTDMRs chr8 22442766 22447432 2.72E−07 −41.2665733 Hypo-methylated PCa|NTDMRs chr8 22547685 22548978 6.51E−11 36.50228175 Hyper-methylated PCa|NTDMRs chr8 22559691 22571369 8.70E−08 23.43117386 Hyper-methylated PCa|NTDMRs chr8 22605261 22605358 0.007959104 21.22040816 Hyper-methylatedPCa|NT DMRs chr8 22626344 22632950 0.000132819 −23.44179894Hypo-methylated PCa|NT DMRs chr8 23146336 23150322 0.002585277−30.90535714 Hypo-methylated PCa|NT DMRs chr8 23260500 23261067 1.00E−1131.93865546 Hyper-methylated PCa|NT DMRs chr8 24529557 245298110.005968871 −37.31428571 Hypo-methylated PCa|NT DMRs chr8 2510581525106146 0.001042833 −32.54285714 Hypo-methylated PCa|NT DMRs chr825678812 25681778 8.35E−08 −32.84761905 Hypo-methylated PCa|NT DMRs chr826047518 26047944 5.27E−07 22.40326531 Hyper-methylated PCa|NT DMRs chr826060747 26062632 0.001896858 −35.30899471 Hypo-methylated PCa|NT DMRschr8 26295201 26298861 6.50E−07 46.72444444 Hyper-methylated PCa|NT DMRschr8 26314979 26323381 0.001969641 −47.42857143 Hypo-methylated PCa|NTDMRs chr8 26434373 26434423 0.004057568 20.54761905 Hyper-methylatedPCa|NT DMRs chr8 26476734 26487972 0.000328483 −23.34603175Hypo-methylated PCa|NT DMRs chr8 27141129 27145133 0.00139740425.37428571 Hyper-methylated PCa|NT DMRs chr8 27331576 273375710.00379014  −29.76190476 Hypo-methylated PCa|NT DMRs chr8 2744126127441384 0.004095673 −45.68253968 Hypo-methylated PCa|NT DMRs chr827467666 27469002 0.002767976 35.57272727 Hyper-methylated PCa|NT DMRschr8 28051550 28051712 0.000836132 35.47671958 Hyper-methylated PCa|NTDMRs chr8 28636837 28637198 1.45E−06 45.50113379 Hyper-methylated PCa|NTDMRs chr8 29205513 29205929 3.20E−05 24.87619048 Hyper-methylated PCa|NTDMRs chr8 30819100 30860251 0.000974795 −33.19345238 Hypo-methylatedPCa|NT DMRs chr8 31072942 31100884 1.19E−05 −26.08857143 Hypo-methylatedPCa|NT DMRs chr8 32083616 32394396 9.19E−10 −39.67403994 Hypo-methylatedPCa|NT DMRs chr8 32435759 32985289 3.17E−12 −39.2018315 Hypo-methylatedPCa|NT DMRs chr8 33432197 33432618 0.001789867 27.39153439Hyper-methylated PCa|NT DMRs chr8 36064877 36530119 5.49E−16 −38.4218254Hypo-methylated PCa|NT DMRs chr8 37082339 37082626 2.20E−08 35.6140056Hyper-methylated PCa|NT DMRs chr8 37554902 37561253 1.01E−20 26.84407369Hyper-methylated PCa|NT DMRs chr8 37605454 37605718 0.00848240527.42857143 Hyper-methylated PCa|NT DMRs chr8 37692789 376966720.001279232 −21.61640212 Hypo-methylated PCa|NT DMRs chr8 3769869237698866 0.000860601 28 Hyper-methylated PCa|NT DMRs chr8 3769912437700577 5.68E−21 −22.48994048 Hypo-methylated PCa|NT DMRs chr8 3779353337797680 0.000513415 −23.73809524 Hypo-methylated PCa|NT DMRs chr838287269 38287486 0.000205174 25.09722222 Hyper-methylated PCa|NT DMRschr8 38494742 38508706 0.000118965 21.47979798 Hyper-methylated PCa|NTDMRs chr8 38586772 38592424 0.00903722  −22.7 Hypo-methylated PCa|NTDMRs chr8 38757333 38757879 1.37E−09 47.41393298 Hyper-methylated PCa|NTDMRs chr8 38965081 38965322 2.80E−09 24.47252747 Hyper-methylated PCa|NTDMRs chr8 41400789 41416396 8.17E−05 −50.13852814 Hypo-methylated PCa|NTDMRs chr8 41423303 41425291 1.86E−05 42.4057971 Hyper-methylated PCa|NTDMRs chr8 41506810 41507551 0.000176046 −21.15757576 Hypo-methylatedPCa|NT DMRs chr8 41522584 41523993 0.00037547  −32.72349206Hypo-methylated PCa|NT DMRs chr8 41540512 41541906 0.00428898927.41456583 Hyper-methylated PCa|NT DMRs chr8 41640907 416704740.005429387 27.303125 Hyper-methylated PCa|NT DMRs chr8 4215467042154952 0.005968871 −42.1552381 Hypo-methylated PCa|NT DMRs chr842328772 42329926 0.003871035 −51.67321429 Hypo-methylated PCa|NT DMRschr8 42571805 42580051 0.002094   −28.13214286 Hypo-methylated PCa|NTDMRs chr8 42660980 42662690 0.009407512 −37.80687831 Hypo-methylatedPCa|NT DMRs chr8 42922954 42923136 0.001969641 −50.47619048Hypo-methylated PCa|NT DMRs chr8 49308856 49309427 0.00013693335.66369048 Hyper-methylated PCa|NT DMRs chr8 49485249 49495212 2.28E−14−53.23150963 Hypo-methylated PCa|NT DMRs chr8 50920607 51383421 2.00E−20−34.0789011 Hypo-methylated PCa|NT DMRs chr8 51767499 51787314 6.42E−05−28.62169312 Hypo-methylated PCa|NT DMRs chr8 54789846 54792185 1.46E−1637.08552754 Hyper-methylated PCa|NT DMRs chr8 55300553 55338708 4.45E−08−35.42126984 Hypo-methylated PCa|NT DMRs chr8 58375388 583926880.006410012 24.82900433 Hyper-methylated PCa|NT DMRs chr8 6117666661183652 0.007560755 −41.16369048 Hypo-methylated PCa|NT DMRs chr862721086 62887070 0.000826653 −25.34017857 Hypo-methylated PCa|NT DMRschr8 62975784 63092355 6.36E−11 −29.25434174 Hypo-methylated PCa|NT DMRschr8 65499369 65499825 5.94E−06 47.97186147 Hyper-methylated PCa|NT DMRschr8 65711626 65711691 0.000205174 44.84821429 Hyper-methylated PCa|NTDMRs chr8 67024862 67025042 0.000831781 21.35238095 Hyper-methylatedPCa|NT DMRs chr8 68733543 68733639 0.005968871 −40.75333333Hypo-methylated PCa|NT DMRs chr8 70744312 70745250 0.00011769921.05612245 Hyper-methylated PCa|NT DMRs chr8 70944891 70947091 1.25E−0620.34933333 Hyper-methylated PCa|NT DMRs chr8 71909255 72392773 1.01E−08−38.1212585 Hypo-methylated PCa|NT DMRs chr8 72924085 73151529 1.03E−07−38.28246753 Hypo-methylated PCa|NT DMRs chr8 74332435 743395120.000396946 −32.76011905 Hypo-methylated PCa|NT DMRs chr8 7466005774660428 0.001969641 27.88492063 Hyper-methylated PCa|NT DMRs chr879899956 79945510 5.94E−06 −34.44588745 Hypo-methylated PCa|NT DMRs chr879982432 80212085 3.19E−07 −33.47380952 Hypo-methylated PCa|NT DMRs chr880255996 80518425 1.57E−08 −33.50419501 Hypo-methylated PCa|NT DMRs chr881806094 81806180 0.000957078 25.03571429 Hyper-methylated PCa|NT DMRschr8 82543201 82543456 1.52E−07 51.25034014 Hyper-methylated PCa|NT DMRschr8 83572888 83791937 1.43E−05 −20.7210084 Hypo-methylated PCa|NT DMRschr8 84053134 84164157 1.16E−06 −32.70535714 Hypo-methylated PCa|NT DMRschr8 84470335 84598492 0.000364072 −22.97985348 Hypo-methylated PCa|NTDMRs chr8 84642023 84844029 1.87E−09 −27.3543514 Hypo-methylated PCa|NTDMRs chr8 86350545 86351196 4.43E−10 33.51890332 Hyper-methylated PCa|NTDMRs chr8 87081679 87081820 4.98E−06 33.8115942 Hyper-methylated PCa|NTDMRs chr8 87648629 88037918 4.97E−13 −33.69057337 Hypo-methylated PCa|NTDMRs chr8 88085853 89250760 7.81E−43 −33.8699232 Hypo-methylated PCa|NTDMRs chr8 89369973 89872954 2.63E−12 −37.39082462 Hypo-methylated PCa|NTDMRs chr8 90547495 90547562 0.000974795 −20.44642857 Hypo-methylatedPCa|NT DMRs chr8 91109576 91488000 9.17E−09 −37.21071429 Hypo-methylatedPCa|NT DMRs chr8 94508105 94508296 4.90E−08 33.83896104 Hyper-methylatedPCa|NT DMRs chr8 96085404 96085917 4.53E−09 44.45402299 Hyper-methylatedPCa|NT DMRs chr8 97156648 97172784 2.52E−46 23.67092829 Hyper-methylatedPCa|NT DMRs chr8 97173592 97174041 0.002437742 31.68253968Hyper-methylated PCa|NT DMRs chr8 98271656 98271950 0.00196964144.23015873 Hyper-methylated PCa|NT DMRs chr8 98617520 986192420.000305995 −21.7952381 Hypo-methylated PCa|NT DMRs chr8 9995178799953050 1.11E−25 40.70776644 Hyper-methylated PCa|NT DMRs chr8101118292 101118744 8.86E−09 21.7537594 Hyper-methylated PCa|NT DMRschr8 101821841 101822591 0.005672841 53.50238095 Hyper-methylated PCa|NTDMRs chr8 102236113 102236447 1.67E−06 51.75210084 Hyper-methylatedPCa|NT DMRs chr8 102373999 102404615 1.97E−05 −44.41047619Hypo-methylated PCa|NT DMRs chr8 102431303 102450992 3.75E−05−52.6172619 Hypo-methylated PCa|NT DMRs chr8 103668997 1036701010.000455672 29.63690476 Hyper-methylated PCa|NT DMRs chr8 103671436103698389 0.005968871 −26.67619048 Hypo-methylated PCa|NT DMRs chr8103750821 103751040 1.42E−05 26.43707483 Hyper-methylated PCa|NT DMRschr8 105342233 105342450 0.001115302 49.48809524 Hyper-methylated PCa|NTDMRs chr8 105379665 105379943 0.001254235 25.10622711 Hyper-methylatedPCa|NT DMRs chr8 108579034 108601690 6.96E−08 −30.73022774Hypo-methylated PCa|NT DMRs chr8 109799167 109799880 9.88E−1523.92774327 Hyper-methylated PCa|NT DMRs chr8 111600692 1120532133.50E−24 −32.73809524 Hypo-methylated PCa|NT DMRs chr8 112065032112663088 1.33E−25 −29.19802956 Hypo-methylated PCa|NT DMRs chr8115228664 115332842 3.60E−14 −28.77045455 Hypo-methylated PCa|NT DMRschr8 115530086 115614442 2.01E−07 −37.82595238 Hypo-methylated PCa|NTDMRs chr8 115887740 116071882 1.10E−13 −37.18809524 Hypo-methylatedPCa|NT DMRs chr8 117991719 118023209 3.66E−05 −25.53333333Hypo-methylated PCa|NT DMRs chr8 118632824 118785270 6.94E−06−36.28507937 Hypo-methylated PCa|NT DMRs chr8 120685356 1206947521.48E−06 −24.65194805 Hypo-methylated PCa|NT DMRs chr8 120779442120779900 0.00569382  −33.87 Hypo-methylated PCa|NT DMRs chr8 121137120121138498 2.35E−05 32.21889401 Hyper-methylated PCa|NT DMRs chr8123928248 123928529 0.005968871 −26.21714286 Hypo-methylated PCa|NT DMRschr8 124173160 124173634 1.68E−06 26.69568452 Hyper-methylated PCa|NTDMRs chr8 124194759 124195440 0.009379999 21.375 Hyper-methylated PCa|NTDMRs chr8 126737168 127493574 2.75E−16 −32.96657682 Hypo-methylatedPCa|NT DMRs chr8 127889338 127889425 0.005968871 −30.94285714Hypo-methylated PCa|NT DMRs chr8 128824018 128826584 0.00064571 37.52721088 Hyper-methylated PCa|NT DMRs chr8 128923716 1289237750.004095673 −42.14285714 Hypo-methylated PCa|NT DMRs chr8 129165439129165636 0.00064571  −62.44897959 Hypo-methylated PCa|NT DMRs chr8129771078 129807059 4.34E−05 −45.92380952 Hypo-methylated PCa|NT DMRschr8 129870344 130645891 4.90E−17 −33.64317998 Hypo-methylated PCa|NTDMRs chr8 130708576 130848921 0.001612399 −23.10076805 Hypo-methylatedPCa|NT DMRs chr8 131000521 131010839 0.006743251 28.3015873Hyper-methylated PCa|NT DMRs chr8 131455250 131455494 4.27E−05 20.739599Hyper-methylated PCa|NT DMRs chr8 131475677 131476021 0.000836132−41.24761905 Hypo-methylated PCa|NT DMRs chr8 131610370 1319337931.57E−09 −32.36728778 Hypo-methylated PCa|NT DMRs chr8 132133320132257632 6.42E−05 −42.98941799 Hypo-methylated PCa|NT DMRs chr8133707885 133769795 9.76E−07 −28.08058608 Hypo-methylated PCa|NT DMRschr8 134498266 134513593 4.37E−05 48.26696429 Hyper-methylated PCa|NTDMRs chr8 135194427 135306812 2.06E−05 −39.13401361 Hypo-methylatedPCa|NT DMRs chr8 135338267 135465459 9.32E−06 −25.83571429Hypo-methylated PCa|NT DMRs chr8 135919142 135973097 6.74E−11−32.48108466 Hypo-methylated PCa|NT DMRs chr8 136092361 1364490011.86E−10 −30.08013937 Hypo-methylated PCa|NT DMRs chr8 137912402139158455 9.24E−38 −36.98143226 Hypo-methylated PCa|NT DMRs chr8139672296 139672680 0.00068166  27.98511905 Hyper-methylated PCa|NT DMRschr8 139870105 139871676 0.001181579 −28.85170068 Hypo-methylated PCa|NTDMRs chr8 139972115 140630754 4.37E−28 −34.84794974 Hypo-methylatedPCa|NT DMRs chr8 140636481 140642897 7.35E−05 −33.21428571Hypo-methylated PCa|NT DMRs chr8 141052553 141053137 0.001496387−34.99859944 Hypo-methylated PCa|NT DMRs chr8 141100648 1411007180.005968871 −46.48571429 Hypo-methylated PCa|NT DMRs chr8 141108104141108690 0.00218362  21.01820728 Hyper-methylated PCa|NT DMRs chr8141354760 141361215 0.000475166 21.67216117 Hyper-methylated PCa|NT DMRschr8 141568364 141568869 0.001198104 31.32653061 Hyper-methylated PCa|NTDMRs chr8 142095375 142095826 0.000122432 −23.78354978 Hypo-methylatedPCa|NT DMRs chr8 142096025 142097924 0.009106413 47.33571429Hyper-methylated PCa|NT DMRs chr8 142119306 142119501 0.00077515429.23809524 Hyper-methylated PCa|NT DMRs chr8 142248919 1422491490.001969641 60.97619048 Hyper-methylated PCa|NT DMRs chr8 142270147142274529 0.000513415 −29.12346939 Hypo-methylated PCa|NT DMRs chr8142336649 142339724 6.90E−08 32.72210884 Hyper-methylated PCa|NT DMRschr8 142388044 142389061 0.009924186 −38.62010582 Hypo-methylated PCa|NTDMRs chr8 142402682 142402949 0.00358897  −20.62507937 Hypo-methylatedPCa|NT DMRs chr8 142409106 142409703 3.44E−06 −50.375 Hypo-methylatedPCa|NT DMRs chr8 142520479 142523003 0.001346417 −27.49801587Hypo-methylated PCa|NT DMRs chr8 142538775 142545237 0.001064034−26.52312925 Hypo-methylated PCa|NT DMRs chr8 142555472 1425719980.007670329 −20.7464986 Hypo-methylated PCa|NT DMRs chr8 142577155142590916 5.56E−05 −26.45844156 Hypo-methylated PCa|NT DMRs chr8142592894 142593783 0.000672633 −22.68571429 Hypo-methylated PCa|NT DMRschr8 142611236 142626664 1.64E−08 −24.73066667 Hypo-methylated PCa|NTDMRs chr8 142690362 142690771 0.001152293 −29.25460317 Hypo-methylatedPCa|NT DMRs chr8 142692497 142719236 2.11E−11 −22.89033816Hypo-methylated PCa|NT DMRs chr8 142834497 142839706 3.10E−06−27.42212885 Hypo-methylated PCa|NT DMRs chr8 142984467 1429864510.004553481 −43.14285714 Hypo-methylated PCa|NT DMRs chr8 143085128143085663 5.19E−07 −51.40842491 Hypo-methylated PCa|NT DMRs chr8143090744 143091427 1.13E−05 −26.31648352 Hypo-methylated PCa|NT DMRschr8 143096606 143098854 1.23E−07 −21.3584127 Hypo-methylated PCa|NTDMRs chr8 143169844 143183051 4.61E−08 −24.42787456 Hypo-methylatedPCa|NT DMRs chr8 143206946 143208246 7.81E−11 −33.05791506Hypo-methylated PCa|NT DMRs chr8 143210813 143211208 1.43E−05−26.21680672 Hypo-methylated PCa|NT DMRs chr8 143217246 1432256862.74E−07 −25.31105991 Hypo-methylated PCa|NT DMRs chr8 143230687143234651 0.000298021 −24.86607143 Hypo-methylated PCa|NT DMRs chr8143235507 143235930 0.000179253 −22.68131868 Hypo-methylated PCa|NT DMRschr8 143265415 143268430 0.002097193 −48.33469388 Hypo-methylated PCa|NTDMRs chr8 143285996 143286977 0.000205174 −28.26607143 Hypo-methylatedPCa|NT DMRs chr8 143307697 143314436 1.92E−09 −23.54261905Hypo-methylated PCa|NT DMRs chr8 143329928 143331470 6.04E−09−25.66365079 Hypo-methylated PCa|NT DMRs chr8 143342806 1433432810.003809353 −26.52809524 Hypo-methylated PCa|NT DMRs chr8 143382202143383762 3.39E−07 41.1974026 Hyper-methylated PCa|NT DMRs chr8143508582 143522040 4.33E−06 −23.89206349 Hypo-methylated PCa|NT DMRschr8 143544017 143546524 3.54E−18 21.94169001 Hyper-methylated PCa|NTDMRs chr8 143573328 143574583 0.000250214 −21.71071429 Hypo-methylatedPCa|NT DMRs chr8 143624954 143626403 1.10E−07 −43.56037415Hypo-methylated PCa|NT DMRs chr8 143630963 143632473 6.20E−05−20.81972789 Hypo-methylated PCa|NT DMRs chr8 143656202 1436563720.007959104 −21.84013605 Hypo-methylated PCa|NT DMRs chr8 143700112143700184 0.007959104 −27.48979592 Hypo-methylated PCa|NT DMRs chr8143762028 143762485 0.00179283  30.07460317 Hyper-methylated PCa|NT DMRschr8 143832005 143832527 0.007552382 20.72321429 Hyper-methylated PCa|NTDMRs chr8 143850699 143851600 1.46E−06 −40.96825397 Hypo-methylatedPCa|NT DMRs chr8 143977598 143984504 0.000111427 −23.96666667Hypo-methylated PCa|NT DMRs chr8 144105161 144108519 7.12E−1144.30995671 Hyper-methylated PCa|NT DMRs chr8 144118211 1441252530.000544917 −22.93792517 Hypo-methylated PCa|NT DMRs chr8 144178766144188067 0.00064571  −37.2244898 Hypo-methylated PCa|NT DMRs chr8144265064 144268735 4.03E−09 −35.02903828 Hypo-methylated PCa|NT DMRschr8 144283322 144283354 0.005968871 31.88952381 Hyper-methylated PCa|NTDMRs chr8 144371506 144371553 0.001969641 28.46825397 Hyper-methylatedPCa|NT DMRs chr8 144442847 144443233 0.001969641 22.05208333Hyper-methylated PCa|NT DMRs chr8 144464615 144465299 0.000980855−36.82653061 Hypo-methylated PCa|NT DMRs chr8 144476461 1444765300.001115302 −25.94642857 Hypo-methylated PCa|NT DMRs chr8 144480110144480867 3.20E−05 31.3139881 Hyper-methylated PCa|NT DMRs chr8144481225 144482659 3.68E−08 −27.29723502 Hypo-methylated PCa|NT DMRschr8 144487603 144488145 0.001139334 −35.14285714 Hypo-methylated PCa|NTDMRs chr8 144628719 144635319 0.005800294 21.60266667 Hyper-methylatedPCa|NT DMRs chr8 144644321 144645084 0.006410012 −23.57857143Hypo-methylated PCa|NT DMRs chr8 144655447 144656066 0.00118157945.31972789 Hyper-methylated PCa|NT DMRs chr8 144666236 1446664450.008482405 40.35714286 Hyper-methylated PCa|NT DMRs chr8 144680875144681950 0.000111427 −25.23816327 Hypo-methylated PCa|NT DMRs chr8144800968 144801303 3.47E−05 −33.60918367 Hypo-methylated PCa|NT DMRschr8 144809795 144810716 2.21E−20 29.54041812 Hyper-methylated PCa|NTDMRs chr8 144852195 144853210 0.000159126 22.23809524 Hyper-methylatedPCa|NT DMRs chr8 144883852 144884746 0.004231599 −32.10622711Hypo-methylated PCa|NT DMRs chr8 144895169 144895870 0.000308231−23.54428571 Hypo-methylated PCa|NT DMRs chr8 144896231 1448964100.002804846 33.82440476 Hyper-methylated PCa|NT DMRs chr8 144923621144923673 0.000205174 −24.21428571 Hypo-methylated PCa|NT DMRs chr8144964837 144965646 0.000492616 27.80761905 Hyper-methylated PCa|NT DMRschr8 144978099 144980365 0.001969641 −47.42857143 Hypo-methylated PCa|NTDMRs chr8 145003406 145004388 2.63E−12 30.66631823 Hyper-methylatedPCa|NT DMRs chr8 145006178 145007582 1.16E−10 −23.21276596Hypo-methylated PCa|NT DMRs chr8 145010401 145011617 0.00376498226.39087302 Hyper-methylated PCa|NT DMRs chr8 145012905 1450145272.17E−08 26.32010582 Hyper-methylated PCa|NT DMRs chr8 145022596145022790 0.005968871 36.85142857 Hyper-methylated PCa|NT DMRs chr8145052060 145054037 3.16E−07 44.11349206 Hyper-methylated PCa|NT DMRschr8 145056465 145059928 1.83E−06 −26.28018433 Hypo-methylated PCa|NTDMRs chr8 145096571 145099295 0.000250214 −35.61190476 Hypo-methylatedPCa|NT DMRs chr8 145129038 145129326 6.42E−05 40.37830688Hyper-methylated PCa|NT DMRs chr8 145162222 145162641 0.000474458−42.04395604 Hypo-methylated PCa|NT DMRs chr8 145237052 1452372630.005968871 −55.96 Hypo-methylated PCa|NT DMRs chr8 145550987 1455511771.62E−05 22.66809524 Hyper-methylated PCa|NT DMRs chr8 145577298145577849 0.006320534 20.82619048 Hyper-methylated PCa|NT DMRs chr8145578008 145578410 2.37E−08 −24.14285714 Hypo-methylated PCa|NT DMRschr8 145646575 145649007 0.004893702 −20.65555556 Hypo-methylated PCa|NTDMRs chr8 145651397 145651575 0.004095673 38.16666667 Hyper-methylatedPCa|NT DMRs chr8 145688603 145690550 0.00530467  −20.52167488Hypo-methylated PCa|NT DMRs chr8 145742341 145742509 3.52E−05−25.88205128 Hypo-methylated PCa|NT DMRs chr8 145749825 1457523114.35E−09 −23.55730428 Hypo-methylated PCa|NT DMRs chr8 145753330145753922 0.000254837 −27.69929453 Hypo-methylated PCa|NT DMRs chr8145755264 145756232 8.06E−11 34.89721254 Hyper-methylated PCa|NT DMRschr8 146253101 146253149 0.002097193 −31.34285714 Hypo-methylated PCa|NTDMRs chr9 83408 83463 0.005968871 −24.2952381 Hypo-methylated PCa|NTDMRs chr9 446271 446461 0.003871035 31.19642857 Hyper-methylated PCa|NTDMRs chr9 804498 811483 0.005295761 −31.46103896 Hypo-methylated PCa|NTDMRs chr9 969611 970971 1.05E−06 21.11133005 Hyper-methylated PCa|NTDMRs chr9 5206951 5327317 0.000370938 −24.56493506 Hypo-methylatedPCa|NT DMRs chr9 5841748 5841963 0.00064571  47.04081633Hyper-methylated PCa|NT DMRs chr9 6412491 6412687 0.00019186329.03720238 Hyper-methylated PCa|NT DMRs chr9 6703571 67036600.001969641 22.98412698 Hyper-methylated PCa|NT DMRs chr9 78799238331761 1.14E−07 −35.46634921 Hypo-methylated PCa|NT DMRs chr9 903271410195094 2.97E−21 −34.10028011 Hypo-methylated PCa|NT DMRs chr9 1419928514203629 0.000783791 −49.77857143 Hypo-methylated PCa|NT DMRs chr914343048 14350085 6.25E−10 35.15319396 Hyper-methylated PCa|NT DMRs chr917018011 17018256 0.00064571  −30.19251701 Hypo-methylated PCa|NT DMRschr9 21138266 21235576 0.00026034  −27.5639881 Hypo-methylated PCa|NTDMRs chr9 21971249 21974592 0.000822388 28.58441558 Hyper-methylatedPCa|NT DMRs chr9 21976437 21993697 0.000149287 35.68907563Hyper-methylated PCa|NT DMRs chr9 23820974 23821145 5.30E−07 21.46469622Hyper-methylated PCa|NT DMRs chr9 23824191 23824651 6.69E−05 31.17142857Hyper-methylated PCa|NT DMRs chr9 24897540 25293313 5.20E−08−28.56365915 Hypo-methylated PCa|NT DMRs chr9 25836072 26315147 1.17E−15−32.91326531 Hypo-methylated PCa|NT DMRs chr9 26664519 26664650 5.94E−06−28.37748918 Hypo-methylated PCa|NT DMRs chr9 27690811 28476568 9.52E−23−34.79254902 Hypo-methylated PCa|NT DMRs chr9 28524474 29135328 1.75E−17−35.78165266 Hypo-methylated PCa|NT DMRs chr9 29215194 29721755 1.21E−08−31.36306306 Hypo-methylated PCa|NT DMRs chr9 31160895 311609790.005968871 −40.49809524 Hypo-methylated PCa|NT DMRs chr9 3126210631570099 2.41E−08 −30.47329193 Hypo-methylated PCa|NT DMRs chr9 3180848232369843 8.62E−09 −25.61503759 Hypo-methylated PCa|NT DMRs chr9 3259741732742987 2.62E−09 −34.24039409 Hypo-methylated PCa|NT DMRs chr9 3281754832876791 2.03E−06 −39.33206349 Hypo-methylated PCa|NT DMRs chr9 3295575432956314 1.29E−08 26.94380952 Hyper-methylated PCa|NT DMRs chr9 3316784533169708 0.000729529 30.48120301 Hyper-methylated PCa|NT DMRs chr933748717 33750047 1.11E−05 47.07575758 Hyper-methylated PCa|NT DMRs chr933750975 33751119 1.69E−06 35.3929972 Hyper-methylated PCa|NT DMRs chr934376267 34376474 0.001344447 22.33928571 Hyper-methylated PCa|NT DMRschr9 34379748 34379985 0.000909347 30.37301587 Hyper-methylated PCa|NTDMRs chr9 34381268 34381893 8.74E−05 30.80434783 Hyper-methylated PCa|NTDMRs chr9 34457260 34457898 0.004967714 −20.79802956 Hypo-methylatedPCa|NT DMRs chr9 34590297 34591619 6.44E−10 36.47135177 Hyper-methylatedPCa|NT DMRs chr9 34652035 34652303 4.82E−06 −20.58184524 Hypo-methylatedPCa|NT DMRs chr9 35406315 35406801 0.005641685 30.70748299Hyper-methylated PCa|NT DMRs chr9 35645028 35646413 0.00992418625.46957672 Hyper-methylated PCa|NT DMRs chr9 35649721 356567190.002695033 25.89732143 Hyper-methylated PCa|NT DMRs chr9 3568973335690528 3.22E−10 32.30334347 Hyper-methylated PCa|NT DMRs chr9 3584626635846608 0.000314499 28.3557423 Hyper-methylated PCa|NT DMRs chr936038139 36038236 1.97E−05 −23.3 Hypo-methylated PCa|NT DMRs chr936137702 36141429 0.001969641 −38.33730159 Hypo-methylated PCa|NT DMRschr9 36458539 36458764 0.00064571  71.5 Hyper-methylated PCa|NT DMRschr9 36765825 36781048 0.002487133 22.17142857 Hyper-methylated PCa|NTDMRs chr9 36842684 36842757 0.005968871 44.46190476 Hyper-methylatedPCa|NT DMRs chr9 37025102 37026367 3.61E−14 22.5452381 Hyper-methylatedPCa|NT DMRs chr9 37515737 37516055 0.000117699 −52.92640693Hypo-methylated PCa|NT DMRs chr9 37938545 37938960 4.82E−06 −27.84136905Hypo-methylated PCa|NT DMRs chr9 38242382 38253497 0.000783791−22.90619048 Hypo-methylated PCa|NT DMRs chr9 38486933 38488409 4.09E−0920.33928571 Hyper-methylated PCa|NT DMRs chr9 38732661 38765566 3.66E−05−33.9 Hypo-methylated PCa|NT DMRs chr9 39062108 39062459 0.008482405−25.88 Hypo-methylated PCa|NT DMRs chr9 39132888 39132940 0.00111530225.5 Hyper-methylated PCa|NT DMRs chr9 40408721 40601658 0.001060348−32.50562771 Hypo-methylated PCa|NT DMRs chr9 43433835 43682005 6.23E−06−29.98917749 Hypo-methylated PCa|NT DMRs chr9 66455995 66456414 1.45E−0628.44489796 Hyper-methylated PCa|NT DMRs chr9 68414144 684142000.003622801 30.4047619 Hyper-methylated PCa|NT DMRs chr9 6919729369197336 0.005968871 33.6352381 Hyper-methylated PCa|NT DMRs chr971222200 71226346 7.19E−05 −22.82142857 Hypo-methylated PCa|NT DMRs chr971735333 71735419 0.000377317 −32.25595238 Hypo-methylated PCa|NT DMRschr9 72990148 72990275 7.57E−05 −37.38134921 Hypo-methylated PCa|NT DMRschr9 74527382 74529776 0.000650326 −42.79960317 Hypo-methylated PCa|NTDMRs chr9 74779823 74942720 4.08E−08 −25.282493 Hypo-methylated PCa|NTDMRs chr9 75533711 75696320 0.000377317 −31.91258503 Hypo-methylatedPCa|NT DMRs chr9 77114273 77115745 5.01E−08 32.87875458 Hyper-methylatedPCa|NT DMRs chr9 78507195 78507575 1.98E−07 40.86428571 Hyper-methylatedPCa|NT DMRs chr9 79093254 79123427 0.005968871 21.79047619Hyper-methylated PCa|NT DMRs chr9 79281044 79293008 0.000117699−40.95238095 Hypo-methylated PCa|NT DMRs chr9 79620790 79629293 1.75E−0625.43760263 Hyper-methylated PCa|NT DMRs chr9 79631191 79631696 1.42E−0525.94727891 Hyper-methylated PCa|NT DMRs chr9 82590302 825903790.001969641 −40 Hypo-methylated PCa|NT DMRs chr9 84117585 841236880.00044133  25.12755102 Hyper-methylated PCa|NT DMRs chr9 8604708486047493 0.008482405 −57.9952381 Hypo-methylated PCa|NT DMRs chr986982507 86987097 0.003448944 29.42857143 Hyper-methylated PCa|NT DMRschr9 87904996 87905325 6.94E−06 45.06190476 Hyper-methylated PCa|NT DMRschr9 88137611 88138101 5.78E−05 35.04325397 Hyper-methylated PCa|NT DMRschr9 88650418 88656424 0.002097193 −25.54217687 Hypo-methylated PCa|NTDMRs chr9 89763714 89763814 0.000836132 28.83333333 Hyper-methylatedPCa|NT DMRs chr9 90864438 90873839 0.000463506 −46.58008658Hypo-methylated PCa|NT DMRs chr9 91150791 91151089 4.00E−05 20.68831169Hyper-methylated PCa|NT DMRs chr9 91792464 91792793 0.00013278220.19588745 Hyper-methylated PCa|NT DMRs chr9 91897310 91911579 8.84E−0526.45833333 Hyper-methylated PCa|NT DMRs chr9 92045970 920507230.001637131 −32.74107143 Hypo-methylated PCa|NT DMRs chr9 9205619092056419 0.00064571  −42.56462585 Hypo-methylated PCa|NT DMRs chr992068640 92082271 0.000652677 23.07380952 Hyper-methylated PCa|NT DMRschr9 92254717 92255951 0.004677148 31.48787879 Hyper-methylated PCa|NTDMRs chr9 93922036 93922272 0.000205174 −24.51845238 Hypo-methylatedPCa|NT DMRs chr9 94648655 94648937 0.000118334 21.52116402Hyper-methylated PCa|NT DMRs chr9 95727723 95728879 5.44E−05 43.67460317Hyper-methylated PCa|NT DMRs chr9 95799473 95799671 0.008482405 23Hyper-methylated PCa|NT DMRs chr9 95906216 95906520 0.00097479544.94642857 Hyper-methylated PCa|NT DMRs chr9 95964146 959658060.000632596 −44.12589286 Hypo-methylated PCa|NT DMRs chr9 9599386995995565 0.005438982 23.20714286 Hyper-methylated PCa|NT DMRs chr996024060 96024937 4.25E−06 −25.74260652 Hypo-methylated PCa|NT DMRs chr996079879 96080176 0.004418655 34.65873016 Hyper-methylated PCa|NT DMRschr9 96104880 96105004 0.004095673 −48.93650794 Hypo-methylated PCa|NTDMRs chr9 96212770 96212839 0.00179283  −20.17857143 Hypo-methylatedPCa|NT DMRs chr9 96443290 96443600 0.002437742 −34.17619048Hypo-methylated PCa|NT DMRs chr9 96572644 96572987 1.80E−06 26.08015873Hyper-methylated PCa|NT DMRs chr9 96670941 96671449 0.00026738323.82285714 Hyper-methylated PCa|NT DMRs chr9 97094722 971085040.002437742 26.66666667 Hyper-methylated PCa|NT DMRs chr9 9731581797317348 2.26E−07 −44.60698413 Hypo-methylated PCa|NT DMRs chr9 9746967697487177 5.03E−05 −20.97238095 Hypo-methylated PCa|NT DMRs chr9 9832697398332587 0.008138809 25.86554622 Hyper-methylated PCa|NT DMRs chr998514556 98514827 0.000463436 23.85555556 Hyper-methylated PCa|NT DMRschr9 98902244 98911780 0.004659837 −27.62337662 Hypo-methylated PCa|NTDMRs chr9 99800899 99800956 0.00068166  30.14285714 Hyper-methylatedPCa|NT DMRs chr9 99838561 99840960 6.00E−08 26.28154762 Hyper-methylatedPCa|NT DMRs chr9 100069566 100069726 2.86E−06 −20.98345865Hypo-methylated PCa|NT DMRs chr9 100337640 100337731 0.00097479548.61011905 Hyper-methylated PCa|NT DMRs chr9 100503347 1005040156.33E−13 23.05957672 Hyper-methylated PCa|NT DMRs chr9 101013423101013498 0.004095673 51.38095238 Hyper-methylated PCa|NT DMRs chr9101352529 101364376 0.005968871 −39.58857143 Hypo-methylated PCa|NT DMRschr9 101378557 101446014 8.34E−11 −29.24510582 Hypo-methylated PCa|NTDMRs chr9 101761074 101761681 0.001969641 −45.53174603 Hypo-methylatedPCa|NT DMRs chr9 101817650 101849787 0.001969641 −21.43401361Hypo-methylated PCa|NT DMRs chr9 102068138 102121756 2.94E−06−32.02970522 Hypo-methylated PCa|NT DMRs chr9 102131248 1022798040.000205174 −24.84333333 Hypo-methylated PCa|NT DMRs chr9 103447815103447986 0.001969641 −27.4047619 Hypo-methylated PCa|NT DMRs chr9104248322 104248763 7.59E−06 23.42113095 Hyper-methylated PCa|NT DMRschr9 105365772 105366360 0.003391914 −24.61164021 Hypo-methylated PCa|NTDMRs chr9 106168220 106458650 2.85E−10 −27.95935374 Hypo-methylatedPCa|NT DMRs chr9 106647199 106761810 5.19E−07 −25.18595238Hypo-methylated PCa|NT DMRs chr9 107101282 107396403 9.12E−15−31.75291005 Hypo-methylated PCa|NT DMRs chr9 109177376 1091774660.001969641 −20.10396825 Hypo-methylated PCa|NT DMRs chr9 110249133110249460 6.42E−05 −21.88941799 Hypo-methylated PCa|NT DMRs chr9110252769 110253913 1.71E−06 34.01445578 Hyper-methylated PCa|NT DMRschr9 112231636 112240133 0.000644025 −32.92207792 Hypo-methylated PCa|NTDMRs chr9 112810291 112812848 2.75E−18 22.33174603 Hyper-methylatedPCa|NT DMRs chr9 112889589 112890061 1.76E−06 39.8234127Hyper-methylated PCa|NT DMRs chr9 112965233 112976082 0.007428376−23.84102564 Hypo-methylated PCa|NT DMRs chr9 113054494 1130547621.66E−07 −22.31298701 Hypo-methylated PCa|NT DMRs chr9 113352499113523988 1.68E−05 −29.31755952 Hypo-methylated PCa|NT DMRs chr9114247331 114247380 0.004095673 −60.11904762 Hypo-methylated PCa|NT DMRschr9 114392697 114392920 0.007338757 −20.25 Hypo-methylated PCa|NT DMRschr9 114654158 114654396 0.005968871 −62.5047619 Hypo-methylated PCa|NTDMRs chr9 116225452 116226372 5.25E−18 −58.43559719 Hypo-methylatedPCa|NT DMRs chr9 116310993 116311238 0.000974795 43.35714286Hyper-methylated PCa|NT DMRs chr9 116355917 116357047 0.00084724622.49659864 Hyper-methylated PCa|NT DMRs chr9 116378428 1163786990.007679542 32.57142857 Hyper-methylated PCa|NT DMRs chr9 116450226116450453 1.13E−07 25.25170068 Hyper-methylated PCa|NT DMRs chr9116875626 116875740 0.001969641 −58.51428571 Hypo-methylated PCa|NT DMRschr9 116918588 116919030 0.001924648 25.32683983 Hyper-methylated PCa|NTDMRs chr9 116973629 116982636 0.00179283  −27.81774892 Hypo-methylatedPCa|NT DMRs chr9 116990117 116990215 0.003448944 −27.56802721Hypo-methylated PCa|NT DMRs chr9 117348989 117349622 0.000238853−34.76441103 Hypo-methylated PCa|NT DMRs chr9 118917146 1189195210.001206208 20.45964912 Hyper-methylated PCa|NT DMRs chr9 123656845123657587 1.60E−11 −23.13657143 Hypo-methylated PCa|NT DMRs chr9124384800 124388584 0.001789867 34.82592593 Hyper-methylated PCa|NT DMRschr9 124446950 124461217 0.000237526 26.34854071 Hyper-methylated PCa|NTDMRs chr9 124955349 124955636 0.001969641 −21.36258503 Hypo-methylatedPCa|NT DMRs chr9 124981272 124982930 1.90E−12 27.61475257Hyper-methylated PCa|NT DMRs chr9 125137516 125137660 0.005968871−24.28571429 Hypo-methylated PCa|NT DMRs chr9 126128425 1261294070.000960149 22.09821429 Hyper-methylated PCa|NT DMRs chr9 126440508126440781 0.00068166  −33.59821429 Hypo-methylated PCa|NT DMRs chr9127005260 127005444 0.001969641 25.83730159 Hyper-methylated PCa|NT DMRschr9 127131834 127162872 0.001844396 28.25 Hyper-methylated PCa|NT DMRschr9 127184623 127198296 3.24E−05 −21.25935374 Hypo-methylated PCa|NTDMRs chr9 127203662 127203901 8.96E−05 40.4202381 Hyper-methylatedPCa|NT DMRs chr9 127258043 127258864 7.63E−08 36.79315476Hyper-methylated PCa|NT DMRs chr9 127267027 127267430 1.70E−0524.13659148 Hyper-methylated PCa|NT DMRs chr9 127614742 1276150260.007560755 −42.98511905 Hypo-methylated PCa|NT DMRs chr9 128091150128091197 0.001969641 −48.02380952 Hypo-methylated PCa|NT DMRs chr9128187841 128188016 0.001969641 −51.64285714 Hypo-methylated PCa|NT DMRschr9 128887984 128888102 0.003622801 −41.85793651 Hypo-methylated PCa|NTDMRs chr9 128928193 128932674 0.001969641 −21.08163265 Hypo-methylatedPCa|NT DMRs chr9 129244998 129260546 1.59E−06 21.36792717Hyper-methylated PCa|NT DMRs chr9 129282457 129282630 1.97E−05−24.7652381 Hypo-methylated PCa|NT DMRs chr9 129325429 1293410930.001139334 −21.95238095 Hypo-methylated PCa|NT DMRs chr9 129349072129350141 0.000632596 −34.08441558 Hypo-methylated PCa|NT DMRs chr9129410534 129417651 0.003622801 30.09309524 Hyper-methylated PCa|NT DMRschr9 129884295 129884762 2.04E−05 32.12946429 Hyper-methylated PCa|NTDMRs chr9 130247532 130249679 0.001201396 −20.31111111 Hypo-methylatedPCa|NT DMRs chr9 130325238 130325963 0.00044067  −23.79761905Hypo-methylated PCa|NT DMRs chr9 130461414 130461708 8.37E−1031.02170868 Hyper-methylated PCa|NT DMRs chr9 130498722 1305048367.57E−08 −23.56904762 Hypo-methylated PCa|NT DMRs chr9 130538891130545566 0.000185577 40.24634921 Hyper-methylated PCa|NT DMRs chr9130587934 130590839 2.53E−07 −20.125 Hypo-methylated PCa|NT DMRs chr9130615682 130616791 7.04E−07 27.10555556 Hyper-methylated PCa|NT DMRschr9 130636547 130636911 0.003290817 −32.60059524 Hypo-methylated PCa|NTDMRs chr9 130674451 130677049 5.38E−14 −27.46645503 Hypo-methylatedPCa|NT DMRs chr9 130677075 130678966 0.001496387 31.93109244Hyper-methylated PCa|NT DMRs chr9 130688850 130689743 4.61E−0927.36959707 Hyper-methylated PCa|NT DMRs chr9 130700674 1307008910.000339757 −22.30865801 Hypo-methylated PCa|NT DMRs chr9 130832419130832953 0.003448944 −34.85714286 Hypo-methylated PCa|NT DMRs chr9131170888 131171294 0.00179283  32.25238095 Hyper-methylated PCa|NT DMRschr9 131175224 131176304 0.001171269 −21.94978355 Hypo-methylated PCa|NTDMRs chr9 131386788 131387123 0.004037929 −42.10204082 Hypo-methylatedPCa|NT DMRs chr9 131465280 131466577 1.38E−10 30.27512315Hyper-methylated PCa|NT DMRs chr9 131683132 131683296 0.001969641−47.11904762 Hypo-methylated PCa|NT DMRs chr9 131900965 1319013960.001181579 −47.69795918 Hypo-methylated PCa|NT DMRs chr9 131924511131924927 0.005513661 25.91666667 Hyper-methylated PCa|NT DMRs chr9132033427 132033681 0.007560755 35.23214286 Hyper-methylated PCa|NT DMRschr9 132044733 132045773 0.001326135 23.88291317 Hyper-methylated PCa|NTDMRs chr9 132103515 132103775 0.002575989 24.62857143 Hyper-methylatedPCa|NT DMRs chr9 132105090 132110094 5.39E−07 29.54326241Hyper-methylated PCa|NT DMRs chr9 132113450 132113607 0.00134444730.38214286 Hyper-methylated PCa|NT DMRs chr9 132114691 1321150402.88E−05 35.56302521 Hyper-methylated PCa|NT DMRs chr9 132140620132140820 0.007560755 −31.81547619 Hypo-methylated PCa|NT DMRs chr9132146225 132146375 1.17E−06 32.84461153 Hyper-methylated PCa|NT DMRschr9 132200296 132201118 5.51E−08 33.07942857 Hyper-methylated PCa|NTDMRs chr9 132221713 132221936 6.94E−06 42.39047619 Hyper-methylatedPCa|NT DMRs chr9 132339296 132339428 0.001139334 26.54761905Hyper-methylated PCa|NT DMRs chr9 132360185 132360352 0.00795910423.53741497 Hyper-methylated PCa|NT DMRs chr9 132513968 1325152592.12E−10 −33.7258658 Hypo-methylated PCa|NT DMRs chr9 132539132132540261 0.008109221 30.72142857 Hyper-methylated PCa|NT DMRs chr9132547203 132547573 0.005968871 −40.88571429 Hypo-methylated PCa|NT DMRschr9 132573788 132574027 0.008482405 −53.66761905 Hypo-methylated PCa|NTDMRs chr9 132625698 132628923 0.000205174 28.90022676 Hyper-methylatedPCa|NT DMRs chr9 132630840 132631703 1.90E−05 26.22574956Hyper-methylated PCa|NT DMRs chr9 132806203 132806281 0.001969641−25.07142857 Hypo-methylated PCa|NT DMRs chr9 132902616 1329141330.004668266 24.87012987 Hyper-methylated PCa|NT DMRs chr9 132935542132935819 6.83E−06 20.69691877 Hyper-methylated PCa|NT DMRs chr9133320532 133320970 6.38E−09 24.44704185 Hyper-methylated PCa|NT DMRschr9 133335225 133335709 0.00179283  −32.6547619 Hypo-methylated PCa|NTDMRs chr9 133347391 133348397 9.19E−06 21.0499232 Hyper-methylatedPCa|NT DMRs chr9 133534738 133534957 3.40E−07 21.96942356Hyper-methylated PCa|NT DMRs chr9 133759698 133760095 0.000118421−27.97619048 Hypo-methylated PCa|NT DMRs chr9 133794267 1337945120.000494377 −23.23469388 Hypo-methylated PCa|NT DMRs chr9 133873921133874195 0.001969641 −29.88571429 Hypo-methylated PCa|NT DMRs chr9133887793 133887962 0.00203766  20.27529762 Hyper-methylated PCa|NT DMRschr9 133888184 133888470 0.002225326 −20.83435374 Hypo-methylated PCa|NTDMRs chr9 133927945 133936600 0.000255766 −27.40301587 Hypo-methylatedPCa|NT DMRs chr9 133943638 133945604 0.000145094 −31 Hypo-methylatedPCa|NT DMRs chr9 134127729 134134288 9.89E−08 39.82989418Hyper-methylated PCa|NT DMRs chr9 134140802 134151912 2.39E−1239.86805556 Hyper-methylated PCa|NT DMRs chr9 134210073 1342102060.002097193 28.47278912 Hyper-methylated PCa|NT DMRs chr9 134212146134220286 0.004047992 −27.46428571 Hypo-methylated PCa|NT DMRs chr9134297287 134299109 1.46E−06 −49.08174603 Hypo-methylated PCa|NT DMRschr9 134473572 134478164 0.001756926 30.19220779 Hyper-methylated PCa|NTDMRs chr9 134604995 134609201 0.000615345 40.07509158 Hyper-methylatedPCa|NT DMRs chr9 134630119 134630474 0.000205174 −55.63095238Hypo-methylated PCa|NT DMRs chr9 134959086 135007487 0.0019106 −34.88690476 Hypo-methylated PCa|NT DMRs chr9 135083747 1350839070.001969641 36.10714286 Hyper-methylated PCa|NT DMRs chr9 135114175135116391 0.001579579 23.73959184 Hyper-methylated PCa|NT DMRs chr9135300108 135302910 0.000140867 21.50151515 Hyper-methylated PCa|NT DMRschr9 135362072 135362111 0.004095673 −24.23809524 Hypo-methylated PCa|NTDMRs chr9 135645997 135646062 1.97E−05 37.24285714 Hyper-methylatedPCa|NT DMRs chr9 135878361 135879598 7.18E−06 36.31142857Hyper-methylated PCa|NT DMRs chr9 135926228 135926392 0.000205174−44.60714286 Hypo-methylated PCa|NT DMRs chr9 135987563 1359907060.000154566 26.72619048 Hyper-methylated PCa|NT DMRs chr9 135994524135995266 1.44E−08 −32.85839599 Hypo-methylated PCa|NT DMRs chr9136004538 136004699 0.001969641 −27.88888889 Hypo-methylated PCa|NT DMRschr9 136005295 136006562 0.005513661 25.21130952 Hyper-methylated PCa|NTDMRs chr9 136038535 136038637 0.00641359  −22.47619048 Hypo-methylatedPCa|NT DMRs chr9 136055928 136060069 0.005968871 −41.65714286Hypo-methylated PCa|NT DMRs chr9 136081567 136082059 0.000787744−30.64285714 Hypo-methylated PCa|NT DMRs chr9 136181528 1361818051.52E−07 −22.21258503 Hypo-methylated PCa|NT DMRs chr9 136182643136190423 0.000564835 −23.85934066 Hypo-methylated PCa|NT DMRs chr9136223912 136225151 0.002142733 −33.26825397 Hypo-methylated PCa|NT DMRschr9 136261602 136262359 0.005855202 −24.41369048 Hypo-methylated PCa|NTDMRs chr9 136325914 136325984 0.002097193 −36.05442177 Hypo-methylatedPCa|NT DMRs chr9 136340066 136341926 0.003736413 20.17800454Hyper-methylated PCa|NT DMRs chr9 136350307 136350525 0.00064571 −51.31496599 Hypo-methylated PCa|NT DMRs chr9 136355192 1363573348.48E−06 −27.99440994 Hypo-methylated PCa|NT DMRs chr9 136390944136391008 0.001969641 −48.86111111 Hypo-methylated PCa|NT DMRs chr9136444128 136444370 3.65E−07 40.43106576 Hyper-methylated PCa|NT DMRschr9 136454214 136460456 0.000131723 −23.82401656 Hypo-methylated PCa|NTDMRs chr9 136487112 136494527 1.97E−05 −28.25857143 Hypo-methylatedPCa|NT DMRs chr9 136531040 136531768 0.001181579 −21.26530612Hypo-methylated PCa|NT DMRs chr9 136566356 136567309 2.64E−0921.59447005 Hyper-methylated PCa|NT DMRs chr9 136567547 1365677740.000117699 36.80519481 Hyper-methylated PCa|NT DMRs chr9 136650408136656275 0.000376085 22.28119048 Hyper-methylated PCa|NT DMRs chr9136720738 136721287 0.00576331  45.48214286 Hyper-methylated PCa|NT DMRschr9 136727388 136728083 0.001992179 48.64761905 Hyper-methylated PCa|NTDMRs chr9 136728421 136729151 0.002373155 −30.3042328 Hypo-methylatedPCa|NT DMRs chr9 136780052 136780592 0.001775064 23.26785714Hyper-methylated PCa|NT DMRs chr9 136797223 136797607 0.000205174−48.87698413 Hypo-methylated PCa|NT DMRs chr9 137184929 1371863870.00020562  20.84586466 Hyper-methylated PCa|NT DMRs chr9 137230496137236620 2.09E−08 33.44629014 Hyper-methylated PCa|NT DMRs chr9137259594 137259966 1.42E−05 −46.93401361 Hypo-methylated PCa|NT DMRschr9 137272603 137274647 6.32E−07 34.08924731 Hyper-methylated PCa|NTDMRs chr9 137277731 137278107 1.42E−05 41.66496599 Hyper-methylatedPCa|NT DMRs chr9 137278588 137279595 9.76E−07 −44.1032967Hypo-methylated PCa|NT DMRs chr9 137287071 137289437 2.80E−1048.47380952 Hyper-methylated PCa|NT DMRs chr9 137304302 1373044890.000575877 35.81601732 Hyper-methylated PCa|NT DMRs chr9 137324570137324813 0.000191452 20.83587302 Hyper-methylated PCa|NT DMRs chr9137347896 137348055 6.93E−09 28.77244898 Hyper-methylated PCa|NT DMRschr9 137662668 137663197 0.000137816 30.58333333 Hyper-methylated PCa|NTDMRs chr9 137734281 137750605 8.64E−09 −20.30021645 Hypo-methylatedPCa|NT DMRs chr9 137968125 137968276 0.001111028 25.31746032Hyper-methylated PCa|NT DMRs chr9 137980515 137981306 0.00014933126.09029982 Hyper-methylated PCa|NT DMRs chr9 137990397 1379905880.000205174 38.26785714 Hyper-methylated PCa|NT DMRs chr9 138047574138067125 8.83E−19 −28.5424812 Hypo-methylated PCa|NT DMRs chr9138076200 138076479 6.42E−05 −29.15555556 Hypo-methylated PCa|NT DMRschr9 138109947 138110400 0.000783791 −30.15238095 Hypo-methylated PCa|NTDMRs chr9 138135823 138136098 6.93E−06 30.00952381 Hyper-methylatedPCa|NT DMRs chr9 138136674 138136896 0.005968871 −46.73809524Hypo-methylated PCa|NT DMRs chr9 138149841 138154779 1.46E−06−25.71496599 Hypo-methylated PCa|NT DMRs chr9 138193989 1382001767.47E−07 −25.56371882 Hypo-methylated PCa|NT DMRs chr9 138285343138285756 0.000205174 −47.47857143 Hypo-methylated PCa|NT DMRs chr9138591535 138592709 7.74E−05 −33.48511905 Hypo-methylated PCa|NT DMRschr9 138672689 138675058 9.71E−09 −23.65463659 Hypo-methylated PCa|NTDMRs chr9 138680915 138681142 0.000321712 −21.3707483 Hypo-methylatedPCa|NT DMRs chr9 138850454 138850548 0.005968871 60.61428571Hyper-methylated PCa|NT DMRs chr9 138870677 138871546 8.49E−0732.17063492 Hyper-methylated PCa|NT DMRs chr9 138874749 1388768800.001430294 −21.91957672 Hypo-methylated PCa|NT DMRs chr9 138976254138976721 0.001201396 24.96507937 Hyper-methylated PCa|NT DMRs chr9138980414 138982640 0.004676045 33.7015873 Hyper-methylated PCa|NT DMRschr9 138985226 138985317 0.003622801 −47.5952381 Hypo-methylated PCa|NTDMRs chr9 138990658 138991054 0.000260936 23.28571429 Hyper-methylatedPCa|NT DMRs chr9 138991834 138992893 0.00101366  −24.83619048Hypo-methylated PCa|NT DMRs chr9 139001785 139003040 7.39E−0740.95361552 Hyper-methylated PCa|NT DMRs chr9 139025711 1390262452.40E−06 31.03361345 Hyper-methylated PCa|NT DMRs chr9 139065586139069481 6.73E−05 −27.638322 Hypo-methylated PCa|NT DMRs chr9 139080397139080622 0.005968871 −32.36666667 Hypo-methylated PCa|NT DMRs chr9139121194 139121849 0.000176046 −37.15151515 Hypo-methylated PCa|NT DMRschr9 139146348 139148504 5.99E−05 −29.32051282 Hypo-methylated PCa|NTDMRs chr9 139220532 139221347 4.40E−07 36.41519274 Hyper-methylatedPCa|NT DMRs chr9 139237010 139237159 0.000190021 28.12987013Hyper-methylated PCa|NT DMRs chr9 139239762 139240697 2.65E−09−38.50571429 Hypo-methylated PCa|NT DMRs chr9 139247030 1392503637.82E−07 −21.89395314 Hypo-methylated PCa|NT DMRs chr9 139260361139260748 0.005513661 39.81071429 Hyper-methylated PCa|NT DMRs chr9139267318 139268274 0.002585277 37.11309524 Hyper-methylated PCa|NT DMRschr9 139271249 139272186 0.000632596 28.57359307 Hyper-methylated PCa|NTDMRs chr9 139371999 139375066 0.009407512 −29.82539683 Hypo-methylatedPCa|NT DMRs chr9 139378639 139379167 2.75E−05 −23.76917989Hypo-methylated PCa|NT DMRs chr9 139416961 139417517 2.04E−0629.54675325 Hyper-methylated PCa|NT DMRs chr9 139426412 1394350771.31E−13 35.21939605 Hyper-methylated PCa|NT DMRs chr9 139472661139473954 0.000227038 30.4534632 Hyper-methylated PCa|NT DMRs chr9139482489 139483401 8.87E−06 34.74285714 Hyper-methylated PCa|NT DMRschr9 139494430 139494944 0.005375157 25.3244898 Hyper-methylated PCa|NTDMRs chr9 139498484 139498705 1.06E−07 43.49773243 Hyper-methylatedPCa|NT DMRs chr9 139506187 139506436 1.69E−06 −45.6697479Hypo-methylated PCa|NT DMRs chr9 139511930 139515432 4.56E−1632.02928827 Hyper-methylated PCa|NT DMRs chr9 139515605 1395185400.000149331 22.59159068 Hyper-methylated PCa|NT DMRs chr9 139522237139523438 3.39E−08 32.51291209 Hyper-methylated PCa|NT DMRs chr9139539576 139546145 2.01E−17 35.12148148 Hyper-methylated PCa|NT DMRschr9 139578490 139581203 3.00E−07 22.94533333 Hyper-methylated PCa|NTDMRs chr9 139587793 139589213 0.001419801 −20.60952381 Hypo-methylatedPCa|NT DMRs chr9 139589454 139589673 0.000205174 −42.07142857Hypo-methylated PCa|NT DMRs chr9 139607683 139610652 6.51E−0638.81096681 Hyper-methylated PCa|NT DMRs chr9 139611890 1396138724.11E−05 31.21025641 Hyper-methylated PCa|NT DMRs chr9 139654998139656264 0.00023371  −30.1 Hypo-methylated PCa|NT DMRs chr9 139725254139725728 6.42E−05 37.17724868 Hyper-methylated PCa|NT DMRs chr9139734936 139735683 2.78E−05 −30.83110119 Hypo-methylated PCa|NT DMRschr9 139796950 139797247 0.000117699 −29.46969697 Hypo-methylated PCa|NTDMRs chr9 139819960 139820197 0.005685503 −30.93650794 Hypo-methylatedPCa|NT DMRs chr9 139837842 139837963 0.001969641 −54.28571429Hypo-methylated PCa|NT DMRs chr9 139841454 139842379 6.34E−06−29.8422619 Hypo-methylated PCa|NT DMRs chr9 139856054 1398563110.00068166  −27.26488095 Hypo-methylated PCa|NT DMRs chr9 139868939139871011 0.00023371  37.21296296 Hyper-methylated PCa|NT DMRs chr9139889122 139892886 1.83E−06 26.30505345 Hyper-methylated PCa|NT DMRschr9 139925092 139929160 4.37E−08 25.04686319 Hyper-methylated PCa|NTDMRs chr9 139952153 139952825 0.000145094 −53.35436508 Hypo-methylatedPCa|NT DMRs chr9 140024941 140025119 0.001055672 24.82653061Hyper-methylated PCa|NT DMRs chr9 140051178 140051233 1.95E−06 23Hyper-methylated PCa|NT DMRs chr9 140111534 140114761 1.56E−11−40.91977226 Hypo-methylated PCa|NT DMRs chr9 140127033 1401274991.35E−06 −22.49689441 Hypo-methylated PCa|NT DMRs chr9 140171190140172989 4.08E−14 38.32194211 Hyper-methylated PCa|NT DMRs chr9140187609 140187811 0.000260936 −38.10952381 Hypo-methylated PCa|NT DMRschr9 140214591 140215570 0.00358897  28.87968254 Hyper-methylated PCa|NTDMRs chr9 140285007 140285942 8.74E−05 −33.60910973 Hypo-methylatedPCa|NT DMRs chr9 140301982 140302294 0.00355142  −25.01575092Hypo-methylated PCa|NT DMRs chr9 140305351 140307130 3.37E−0627.82751323 Hyper-methylated PCa|NT DMRs chr9 140311098 1403125211.16E−21 31.19112782 Hyper-methylated PCa|NT DMRs chr9 140329182140329356 0.000205174 47.71428571 Hyper-methylated PCa|NT DMRs chr9140330432 140334082 3.01E−09 −29.49047619 Hypo-methylated PCa|NT DMRschr9 140341458 140341607 0.005968871 44.68095238 Hyper-methylated PCa|NTDMRs chr9 140459598 140462140 0.001969641 43.12857143 Hyper-methylatedPCa|NT DMRs chr9 140472268 140472540 0.007959104 −24.39795918Hypo-methylated PCa|NT DMRs chr9 140485693 140488177 0.00358897 −35.22285714 Hypo-methylated PCa|NT DMRs chr9 140509383 1405100530.001181579 −45.42857143 Hypo-methylated PCa|NT DMRs chr9 140651601140651808 0.001969641 −57.87755102 Hypo-methylated PCa|NT DMRs chr9140959802 140963403 0.001241245 −23.53703704 Hypo-methylated PCa|NT DMRschr9 141013804 141015318 3.29E−10 −21.13191763 Hypo-methylated PCa|NTDMRs chr10 556444 556706 0.000205174 −26.30357143 Hypo-methylated PCa|NTDMRs chr10 743193 743313 5.84E−05 21.98809524 Hyper-methylated PCa|NTDMRs chr10 835645 836435 0.002595994 −25.62275132 Hypo-methylated PCa|NTDMRs chr10 1155970 1156826 4.68E−05 −24.1712522 Hypo-methylated PCa|NTDMRs chr10 1449800 1449999 0.007959104 22.89795918 Hyper-methylatedPCa|NT DMRs chr10 2543994 2544058 0.00023371  28.58714286Hyper-methylated PCa|NT DMRs chr10 3027998 3028236 0.005968871−23.24761905 Hypo-methylated PCa|NT DMRs chr10 3100042 3109394 1.25E−0827.75649936 Hyper-methylated PCa|NT DMRs chr10 3138410 3138703 1.92E−0546.87058824 Hyper-methylated PCa|NT DMRs chr10 3160926 3161297 1.31E−06−26.71693122 Hypo-methylated PCa|NT DMRs chr10 3234515 32373460.003871035 −21.55357143 Hypo-methylated PCa|NT DMRs chr10 33024543302715 0.000354065 −47.35291005 Hypo-methylated PCa|NT DMRs chr103502753 3512546 0.009106413 −29.08253968 Hypo-methylated PCa|NT DMRschr10 3594345 3596666 0.002529619 38.92307692 Hyper-methylated PCa|NTDMRs chr10 3763180 3788686 0.003290817 25.36071429 Hyper-methylatedPCa|NT DMRs chr10 3791988 3792369 0.001969641 32.53673469Hyper-methylated PCa|NT DMRs chr10 3823758 3823908 4.28E−07 33.53111111Hyper-methylated PCa|NT DMRs chr10 3929019 3929291 0.00064571 −55.57959184 Hypo-methylated PCa|NT DMRs chr10 5530284 55307810.002585277 −20.92857143 Hypo-methylated PCa|NT DMRs chr10 56159865616349 2.05E−05 −39.5969697 Hypo-methylated PCa|NT DMRs chr10 56214575621639 0.00068166  −51.03869048 Hypo-methylated PCa|NT DMRs chr105731421 5734828 7.34E−05 35.61269841 Hyper-methylated PCa|NT DMRs chr106104182 6107976 0.002097193 23.30612245 Hyper-methylated PCa|NT DMRschr10 6109062 6120302 0.000149331 −27.17489177 Hypo-methylated PCa|NTDMRs chr10 6185717 6186026 5.19E−07 28.71648352 Hyper-methylated PCa|NTDMRs chr10 6187491 6187913 0.00188599  24.84126984 Hyper-methylatedPCa|NT DMRs chr10 6218761 6219158 0.00064571  40.37414966Hyper-methylated PCa|NT DMRs chr10 6246171 6246451 1.45E−05 −20.64880952Hypo-methylated PCa|NT DMRs chr10 6297892 6298058 0.001969641−40.26530612 Hypo-methylated PCa|NT DMRs chr10 6302269 63176780.008649834 25.42857143 Hyper-methylated PCa|NT DMRs chr10 67635326775012 0.00641359  −48.3015873 Hypo-methylated PCa|NT DMRs chr108075716 8076637 5.33E−12 29.71863354 Hyper-methylated PCa|NT DMRs chr1011472552 11475258 0.001344447 −49.50892857 Hypo-methylated PCa|NT DMRschr10 11504160 11504220 0.004095673 29.01984127 Hyper-methylated PCa|NTDMRs chr10 11682342 11684889 0.001969641 35.50714286 Hyper-methylatedPCa|NT DMRs chr10 11737214 11739418 0.00576331  −31.61011905Hypo-methylated PCa|NT DMRs chr10 12380735 12390599 0.002373155−24.61587302 Hypo-methylated PCa|NT DMRs chr10 12390656 123911381.31E−13 20.55137845 Hyper-methylated PCa|NT DMRs chr10 1245865112458983 0.000190021 28.30519481 Hyper-methylated PCa|NT DMRs chr1012468406 12476786 8.49E−05 −28.7568254 Hypo-methylated PCa|NT DMRs chr1012676665 12676771 0.00064571  22.1877551 Hyper-methylated PCa|NT DMRschr10 12948442 12951611 0.001583613 −27.58614719 Hypo-methylated PCa|NTDMRs chr10 13043118 13043450 1.01E−06 23.97883598 Hyper-methylatedPCa|NT DMRs chr10 13442612 13442783 0.005968871 −32.4 Hypo-methylatedPCa|NT DMRs chr10 14305211 14305371 0.005968871 43.22857143Hyper-methylated PCa|NT DMRs chr10 15077227 15077528 0.00037731730.11666667 Hyper-methylated PCa|NT DMRs chr10 21788694 217897022.69E−05 38.50412698 Hyper-methylated PCa|NT DMRs chr10 2179852821804387 0.00015558  27.81165846 Hyper-methylated PCa|NT DMRs chr1022660428 22660476 0.005968871 −38.23333333 Hypo-methylated PCa|NT DMRschr10 22760891 22766904 8.13E−20 34.17026307 Hyper-methylated PCa|NTDMRs chr10 23460647 23461376 0.001610287 27.44960317 Hyper-methylatedPCa|NT DMRs chr10 23551094 23631462 4.82E−05 −23.72071429Hypo-methylated PCa|NT DMRs chr10 27234975 27235299 0.001076343−28.46753247 Hypo-methylated PCa|NT DMRs chr10 27519447 275278545.94E−06 −31.2012987 Hypo-methylated PCa|NT DMRs chr10 27702649 277028495.84E−05 26.16071429 Hyper-methylated PCa|NT DMRs chr10 2797873927978860 0.00064571  −53.15646259 Hypo-methylated PCa|NT DMRs chr1028030428 28030952 4.32E−05 45.58974359 Hyper-methylated PCa|NT DMRschr10 28965390 28965937 1.65E−06 22.6366843 Hyper-methylated PCa|NT DMRschr10 29201275 29214362 0.00179283  26.78253968 Hyper-methylated PCa|NTDMRs chr10 29228804 29265453 0.006589535 −30.21428571 Hypo-methylatedPCa|NT DMRs chr10 29666139 29667292 0.001480644 −33.87714286Hypo-methylated PCa|NT DMRs chr10 29771617 29771828 0.00196964133.11904762 Hyper-methylated PCa|NT DMRs chr10 30452793 304529370.007338757 33.48214286 Hyper-methylated PCa|NT DMRs chr10 3076588230765936 0.005968871 39.17142857 Hyper-methylated PCa|NT DMRs chr1030950283 30973199 0.005572785 −21.4959707 Hypo-methylated PCa|NT DMRschr10 31875888 31876293 0.000205174 39.23571429 Hyper-methylated PCa|NTDMRs chr10 32039435 32046741 0.004417112 −27.02040816 Hypo-methylatedPCa|NT DMRs chr10 32514672 32522497 0.001969641 −22.62698413Hypo-methylated PCa|NT DMRs chr10 34827654 34827714 0.001969641−32.11904762 Hypo-methylated PCa|NT DMRs chr10 36188221 361882920.004095673 −55.11904762 Hypo-methylated PCa|NT DMRs chr10 3744878337483524 0.000205174 −36.46428571 Hypo-methylated PCa|NT DMRs chr1038300369 38300428 0.005513661 −20.06122449 Hypo-methylated PCa|NT DMRschr10 42490532 42644711 1.05E−09 −23.64537037 Hypo-methylated PCa|NTDMRs chr10 42676531 42730315 0.002097193 −27.33605442 Hypo-methylatedPCa|NT DMRs chr10 43366821 43367062 0.001969641 27.66666667Hyper-methylated PCa|NT DMRs chr10 43600358 43600734 8.41E−1438.53117914 Hyper-methylated PCa|NT DMRs chr10 43846514 438467062.50E−05 25.31150794 Hyper-methylated PCa|NT DMRs chr10 4391239343913156 0.003871035 36.33253968 Hyper-methylated PCa|NT DMRs chr1044787939 44806375 0.00044067  26.27819549 Hyper-methylated PCa|NT DMRschr10 45323025 45324261 3.20E−05 −33.77380952 Hypo-methylated PCa|NTDMRs chr10 45741465 45745225 0.005968871 −26.55384615 Hypo-methylatedPCa|NT DMRs chr10 45755738 45755810 6.42E−05 −33.32592593Hypo-methylated PCa|NT DMRs chr10 46970108 46970377 4.00E−07 27.84432234Hyper-methylated PCa|NT DMRs chr10 46993211 46993637 3.70E−0633.44347826 Hyper-methylated PCa|NT DMRs chr10 47638123 476382090.001969641 37.34693878 Hyper-methylated PCa|NT DMRs chr10 4845154948451641 0.005968871 −52.43428571 Hypo-methylated PCa|NT DMRs chr1048461111 48485587 6.65E−07 −24.67094017 Hypo-methylated PCa|NT DMRschr10 49459788 49459846 0.005968871 −53.02857143 Hypo-methylated PCa|NTDMRs chr10 49664506 49668100 0.000552328 25.71164021 Hyper-methylatedPCa|NT DMRs chr10 49866754 49891545 0.008234951 −23.3452381Hypo-methylated PCa|NT DMRs chr10 49892861 49892955 0.00596887148.67619048 Hyper-methylated PCa|NT DMRs chr10 49899260 499165171.92E−05 −26.32761905 Hypo-methylated PCa|NT DMRs chr10 5032379350347113 2.26E−07 −31.96 Hypo-methylated PCa|NT DMRs chr10 5037310350374117 1.97E−05 −33.28380952 Hypo-methylated PCa|NT DMRs chr1050404163 50437652 4.28E−07 −28.21580087 Hypo-methylated PCa|NT DMRschr10 50650006 50650326 0.000909347 22.46230159 Hyper-methylated PCa|NTDMRs chr10 50833615 50872572 1.62E−06 −25.29437229 Hypo-methylatedPCa|NT DMRs chr10 50904521 50943452 1.19E−05 −22.5047619 Hypo-methylatedPCa|NT DMRs chr10 51784605 51784889 2.06E−05 29.28469388Hyper-methylated PCa|NT DMRs chr10 52763120 52764080 0.002097193−26.16666667 Hypo-methylated PCa|NT DMRs chr10 52883339 531592725.94E−06 −34.26363636 Hypo-methylated PCa|NT DMRs chr10 5335568353393542 0.00064571  −33.93061224 Hypo-methylated PCa|NT DMRs chr1056935279 57316424 8.42E−15 −27.06092215 Hypo-methylated PCa|NT DMRschr10 57407046 57407383 0.001181579 −26.57142857 Hypo-methylated PCa|NTDMRs chr10 57842848 57862541 0.005968871 −26.17142857 Hypo-methylatedPCa|NT DMRs chr10 58346328 58456612 0.000335271 −25.15384615Hypo-methylated PCa|NT DMRs chr10 58671006 58817079 3.36E−06−25.49068323 Hypo-methylated PCa|NT DMRs chr10 63627786 636279470.00064571  38.37959184 Hyper-methylated PCa|NT DMRs chr10 6380892963809171 2.85E−05 −42.74908425 Hypo-methylated PCa|NT DMRs chr1064646645 64678424 0.00064571  −30.61088435 Hypo-methylated PCa|NT DMRschr10 66084754 66170204 2.13E−06 −30.54738095 Hypo-methylated PCa|NTDMRs chr10 69609835 69610039 0.00603903  −25.72857143 Hypo-methylatedPCa|NT DMRs chr10 70321294 70327140 0.005685503 26.375 Hyper-methylatedPCa|NT DMRs chr10 70846441 70861730 0.006207271 28.11507937Hyper-methylated PCa|NT DMRs chr10 71122398 71135706 0.007560755−22.95343915 Hypo-methylated PCa|NT DMRs chr10 71214813 712325170.007560755 21.20535714 Hyper-methylated PCa|NT DMRs chr10 7142200071422301 0.000974795 −32.92559524 Hypo-methylated PCa|NT DMRs chr1071475998 71476234 0.003448944 −22.30272109 Hypo-methylated PCa|NT DMRschr10 71577803 71583584 0.003871035 −20.80357143 Hypo-methylated PCa|NTDMRs chr10 71596002 71599682 0.006589535 30.71190476 Hyper-methylatedPCa|NT DMRs chr10 71721702 71721874 0.005968871 47.84761905Hyper-methylated PCa|NT DMRs chr10 72043396 72043785 9.29E−0720.50584416 Hyper-methylated PCa|NT DMRs chr10 72218877 722200770.003764982 26.40793651 Hyper-methylated PCa|NT DMRs chr10 7225381572260799 1.71E−06 32.81809524 Hyper-methylated PCa|NT DMRs chr1072325278 72325450 0.005968871 42.99428571 Hyper-methylated PCa|NT DMRschr10 72384433 72390950 0.00046742  −20.81818182 Hypo-methylated PCa|NTDMRs chr10 72898069 72898339 0.000117699 −47.93506494 Hypo-methylatedPCa|NT DMRs chr10 73062374 73062852 0.007560755 −28.07738095Hypo-methylated PCa|NT DMRs chr10 73073033 73077029 0.000205174−51.49107143 Hypo-methylated PCa|NT DMRs chr10 73155765 731565254.08E−06 29.7020592 Hyper-methylated PCa|NT DMRs chr10 73398524 733989013.05E−06 37.21978022 Hyper-methylated PCa|NT DMRs chr10 7342652773426831 0.001181579 36.34693878 Hyper-methylated PCa|NT DMRs chr1073472344 73475785 0.003702731 29.14285714 Hyper-methylated PCa|NT DMRschr10 73484911 73490384 0.000946908 35.23116883 Hyper-methylated PCa|NTDMRs chr10 73494321 73506192 6.25E−05 25.13646259 Hyper-methylatedPCa|NT DMRs chr10 73557712 73558030 0.00064571  43.58503401Hyper-methylated PCa|NT DMRs chr10 73723435 73723843 6.33E−05 26.6884058Hyper-methylated PCa|NT DMRs chr10 73725083 73725232 0.00064571 34.73469388 Hyper-methylated PCa|NT DMRs chr10 73729855 737303850.002562638 −40.49404762 Hypo-methylated PCa|NT DMRs chr10 7384410973848209 3.82E−16 21.18701707 Hyper-methylated PCa|NT DMRs chr1074020487 74020668 0.000377317 29.56428571 Hyper-methylated PCa|NT DMRschr10 74035652 74036091 0.005968871 −42.87142857 Hypo-methylated PCa|NTDMRs chr10 74088723 74095793 0.000455762 26.15014881 Hyper-methylatedPCa|NT DMRs chr10 74928939 74938815 0.002097193 −29.42857143Hypo-methylated PCa|NT DMRs chr10 75475351 75475426 0.005968871−48.03904762 Hypo-methylated PCa|NT DMRs chr10 75579349 755797648.29E−07 −49.02380952 Hypo-methylated PCa|NT DMRs chr10 7650219976503649 0.001789867 33.54497354 Hyper-methylated PCa|NT DMRs chr1076803562 76812891 3.67E−06 31.79333333 Hyper-methylated PCa|NT DMRschr10 79396120 79396710 2.92E−06 20.09897959 Hyper-methylated PCa|NTDMRs chr10 79469897 79471025 0.003362655 23.73296703 Hyper-methylatedPCa|NT DMRs chr10 79637737 79637988 0.005968871 37.8 Hyper-methylatedPCa|NT DMRs chr10 80030398 80037953 0.006225823 −32.08138528Hypo-methylated PCa|NT DMRs chr10 80891971 80911461 1.75E−06 24.40854978Hyper-methylated PCa|NT DMRs chr10 80941264 80947304 0.00019145227.64952381 Hyper-methylated PCa|NT DMRs chr10 80990136 809904050.001789867 32.39100529 Hyper-methylated PCa|NT DMRs chr10 8105318281058392 0.002400984 26.10888889 Hyper-methylated PCa|NT DMRs chr1081074936 81075242 0.000159287 −33.14285714 Hypo-methylated PCa|NT DMRschr10 81163196 81175656 1.13E−05 41.73113553 Hyper-methylated PCa|NTDMRs chr10 81206455 81212255 0.005968871 −28.29375 Hypo-methylatedPCa|NT DMRs chr10 81742882 81743215 1.72E−05 23.98401361Hyper-methylated PCa|NT DMRs chr10 81928358 81928878 0.002437742−22.45661376 Hypo-methylated PCa|NT DMRs chr10 82269180 822693990.00064571  −25.09387755 Hypo-methylated PCa|NT DMRs chr10 8368325683910012 5.52E−05 −27.94829932 Hypo-methylated PCa|NT DMRs chr1085997015 85997267 5.95E−07 27.28571429 Hyper-methylated PCa|NT DMRschr10 86004879 86014216 0.004553481 −23.07460317 Hypo-methylated PCa|NTDMRs chr10 86335270 86444165 2.35E−10 −25.32125436 Hypo-methylatedPCa|NT DMRs chr10 86522263 86732049 2.07E−07 −28.32326007Hypo-methylated PCa|NT DMRs chr10 87967682 88010471 8.35E−08−29.10978121 Hypo-methylated PCa|NT DMRs chr10 88127296 881275324.24E−06 24.63909774 Hyper-methylated PCa|NT DMRs chr10 8829498188295574 8.39E−13 −24.65452848 Hypo-methylated PCa|NT DMRs chr1088376246 88392096 4.75E−06 24.43581781 Hyper-methylated PCa|NT DMRschr10 88728350 88728573 1.73E−09 22.20798771 Hyper-methylated PCa|NTDMRs chr10 88730081 88731649 5.37E−22 33.62130326 Hyper-methylatedPCa|NT DMRs chr10 88976060 88976088 0.005968871 42.71428571Hyper-methylated PCa|NT DMRs chr10 90686379 90712685 0.005425083−33.26785714 Hypo-methylated PCa|NT DMRs chr10 90966717 909669420.000480383 21.88359788 Hyper-methylated PCa|NT DMRs chr10 9261668492616848 0.000377317 26.04166667 Hyper-methylated PCa|NT DMRs chr1093504923 93505044 0.005968871 −45.11428571 Hypo-methylated PCa|NT DMRschr10 93999137 93999348 7.88E−06 −37.73809524 Hypo-methylated PCa|NTDMRs chr10 94449893 94451993 1.31E−25 29.08099174 Hyper-methylatedPCa|NT DMRs chr10 94834546 94835374 1.87E−05 25.39455782Hyper-methylated PCa|NT DMRs chr10 95360289 95360614 0.00129406724.01410935 Hyper-methylated PCa|NT DMRs chr10 95683692 956941630.003622801 −20.97619048 Hypo-methylated PCa|NT DMRs chr10 9827223498272754 5.37E−10 22.53243243 Hyper-methylated PCa|NT DMRs chr1098405168 98446983 0.000205174 34.05619048 Hyper-methylated PCa|NT DMRschr10 98760392 98760812 0.001480644 −36.59047619 Hypo-methylated PCa|NTDMRs chr10 98913759 98923658 0.005968871 −21.6047619 Hypo-methylatedPCa|NT DMRs chr10 99125969 99126316 0.000443725 27.55119048Hyper-methylated PCa|NT DMRs chr10 99664428 99665496 0.00028623823.00915751 Hyper-methylated PCa|NT DMRs chr10 99790772 997987633.69E−08 25.2609127 Hyper-methylated PCa|NT DMRs chr10 100150666100150938 0.001969641 36.14047619 Hyper-methylated PCa|NT DMRs chr10100227729 100282177 0.004497523 21.29503968 Hyper-methylated PCa|NT DMRschr10 101279686 101280310 0.000649993 32.31501832 Hyper-methylatedPCa|NT DMRs chr10 101283053 101283302 0.000974795 25.26130952Hyper-methylated PCa|NT DMRs chr10 101295496 101300263 4.44E−1533.24034632 Hyper-methylated PCa|NT DMRs chr10 101875003 1018750601.42E−05 30.29931973 Hyper-methylated PCa|NT DMRs chr10 102329603102329989 0.000847246 22.58945578 Hyper-methylated PCa|NT DMRs chr10102748904 102749079 0.001969641 −45.88095238 Hypo-methylated PCa|NT DMRschr10 102791787 102792473 5.05E−15 21.59593254 Hyper-methylated PCa|NTDMRs chr10 102807574 102808087 2.08E−06 24.36153846 Hyper-methylatedPCa|NT DMRs chr10 103043851 103044324 2.53E−10 37.2264881Hyper-methylated PCa|NT DMRs chr10 103053118 103070481 8.87E−0527.51580952 Hyper-methylated PCa|NT DMRs chr10 103329251 1033294720.000632596 20.51428571 Hyper-methylated PCa|NT DMRs chr10 103589048103589516 0.000392715 32.24047619 Hyper-methylated PCa|NT DMRs chr10103830984 103831047 0.000205174 40.5297619 Hyper-methylated PCa|NT DMRschr10 104211167 104211389 0.005513661 −23.83673469 Hypo-methylatedPCa|NT DMRs chr10 104233380 104233458 0.000205174 26.71428571Hyper-methylated PCa|NT DMRs chr10 104416887 104419465 5.58E−05−32.61851852 Hypo-methylated PCa|NT DMRs chr10 104433792 1044342451.76E−06 47.08412698 Hyper-methylated PCa|NT DMRs chr10 104629681104629912 0.00641359  31.00238095 Hyper-methylated PCa|NT DMRs chr10104679287 104679334 0.002585277 21.75 Hyper-methylated PCa|NT DMRs chr10105157285 105176631 2.52E−05 −34.6302521 Hypo-methylated PCa|NT DMRschr10 105376624 105376761 3.51E−05 25.56043956 Hyper-methylated PCa|NTDMRs chr10 105423558 105423915 2.06E−05 −38.65544218 Hypo-methylatedPCa|NT DMRs chr10 106081178 106097511 0.000775154 31.20734127Hyper-methylated PCa|NT DMRs chr10 106174588 106195165 1.76E−06−35.39285714 Hypo-methylated PCa|NT DMRs chr10 110092420 1101871020.00266883  −29.59809524 Hypo-methylated PCa|NT DMRs chr10 111766841111767609 1.29E−05 25.30672269 Hyper-methylated PCa|NT DMRs chr10112193490 112193856 0.00641359  −41.91666667 Hypo-methylated PCa|NT DMRschr10 112838347 112847422 5.13E−14 28.0691358 Hyper-methylated PCa|NTDMRs chr10 114059288 114074175 0.00891501  −20.15963719 Hypo-methylatedPCa|NT DMRs chr10 114823362 114833756 0.004236974 −25.82857143Hypo-methylated PCa|NT DMRs chr10 115033264 115033784 0.00118157939.10204082 Hyper-methylated PCa|NT DMRs chr10 115279121 1152792970.001969641 −34.27380952 Hypo-methylated PCa|NT DMRs chr10 115897350115925464 0.005513661 −23.8170068 Hypo-methylated PCa|NT DMRs chr10115940219 115940529 0.000205174 −54.41964286 Hypo-methylated PCa|NT DMRschr10 116162884 116162984 0.001969641 47.14285714 Hyper-methylatedPCa|NT DMRs chr10 116164640 116165087 0.003541715 20.3415873Hyper-methylated PCa|NT DMRs chr10 116307367 116323944 1.26E−0537.43968254 Hyper-methylated PCa|NT DMRs chr10 117591036 1179977144.16E−23 −26.63263985 Hypo-methylated PCa|NT DMRs chr10 118030475118031355 5.93E−19 20.07562657 Hyper-methylated PCa|NT DMRs chr10118345648 118364310 0.001969641 −35.20408163 Hypo-methylated PCa|NT DMRschr10 118429481 118429953 0.000251303 22.97732426 Hyper-methylatedPCa|NT DMRs chr10 118464403 118464683 0.003400006 −35.97959184Hypo-methylated PCa|NT DMRs chr10 118891071 118896117 1.75E−3124.41024259 Hyper-methylated PCa|NT DMRs chr10 118927246 1189274641.29E−05 24.60022676 Hyper-methylated PCa|NT DMRs chr10 118928583118928762 0.001969641 27.19047619 Hyper-methylated PCa|NT DMRs chr10119204972 119208689 0.006096657 −26.94444444 Hypo-methylated PCa|NT DMRschr10 119291157 119292588 4.20E−07 28.05590062 Hyper-methylated PCa|NTDMRs chr10 119296516 119296695 6.90E−05 24.8968254 Hyper-methylatedPCa|NT DMRs chr10 119296847 119296894 0.003272154 25.23214286Hyper-methylated PCa|NT DMRs chr10 119304380 119310965 4.38E−3226.43669951 Hyper-methylated PCa|NT DMRs chr10 119444256 1194446420.000260936 −20.97142857 Hypo-methylated PCa|NT DMRs chr10 119650134119681020 0.00064571  −28.05510204 Hypo-methylated PCa|NT DMRs chr10120515032 120515437 0.005375157 30.2414966 Hyper-methylated PCa|NT DMRschr10 121030606 121030663 0.008482405 35.16190476 Hyper-methylatedPCa|NT DMRs chr10 121066077 121066241 0.005968871 51.57142857Hyper-methylated PCa|NT DMRs chr10 121073487 121073656 0.001969641 48.5Hyper-methylated PCa|NT DMRs chr10 121127442 121127615 0.00084072633.69047619 Hyper-methylated PCa|NT DMRs chr10 121252647 1212557860.000424658 28.60090703 Hyper-methylated PCa|NT DMRs chr10 121445679121445881 0.000652677 −35.41071429 Hypo-methylated PCa|NT DMRs chr10122708684 122724071 7.99E−07 36.90026455 Hyper-methylated PCa|NT DMRschr10 122739457 122759005 0.005646573 40.21428571 Hyper-methylatedPCa|NT DMRs chr10 123229472 123250537 0.001254235 −41.46483516Hypo-methylated PCa|NT DMRs chr10 123333228 123333456 0.000118733−42.40899471 Hypo-methylated PCa|NT DMRs chr10 123733690 1237338440.001969641 −22.45 Hypo-methylated PCa|NT DMRs chr10 123778434 1237817413.20E−05 −42.08644689 Hypo-methylated PCa|NT DMRs chr10 123873842123874281 0.005968871 −35.12698413 Hypo-methylated PCa|NT DMRs chr10124058195 124059587 0.005513661 −37.90612245 Hypo-methylated PCa|NT DMRschr10 124233801 124234900 0.006589535 28.50714286 Hyper-methylatedPCa|NT DMRs chr10 124279446 124279587 2.58E−05 −32.86095238Hypo-methylated PCa|NT DMRs chr10 124487395 124557584 7.75E−10−25.18452381 Hypo-methylated PCa|NT DMRs chr10 125220997 1252285590.00017871  −28.61 Hypo-methylated PCa|NT DMRs chr10 125234404 1252399220.002437742 −26.95185185 Hypo-methylated PCa|NT DMRs chr10 125310903125411063 1.17E−18 −31.61390977 Hypo-methylated PCa|NT DMRs chr10125426266 125426294 0.001115302 23.23214286 Hyper-methylated PCa|NT DMRschr10 125428601 125650354 8.22E−24 −33.66460317 Hypo-methylated PCa|NTDMRs chr10 125673698 125727334 2.61E−07 −21.44091711 Hypo-methylatedPCa|NT DMRs chr10 125803689 125815013 0.000874558 −27.55974026Hypo-methylated PCa|NT DMRs chr10 125830141 125847725 0.001563412−28.8802005 Hypo-methylated PCa|NT DMRs chr10 125851162 1258518254.51E−18 27.63044496 Hyper-methylated PCa|NT DMRs chr10 125922278125933051 8.50E−10 −20.69256678 Hypo-methylated PCa|NT DMRs chr10126077501 126077549 0.000481535 27.92063492 Hyper-methylated PCa|NT DMRschr10 126106146 126106294 0.00064571  −35.84693878 Hypo-methylatedPCa|NT DMRs chr10 126222956 126224655 0.001181579 39.86938776Hyper-methylated PCa|NT DMRs chr10 126254410 126254770 0.00641359 −32.50793651 Hypo-methylated PCa|NT DMRs chr10 126300445 1263035570.005295761 34.53030303 Hyper-methylated PCa|NT DMRs chr10 126308381126308821 0.005438982 24.36428571 Hyper-methylated PCa|NT DMRs chr10126363463 126366197 0.003921091 23.62770563 Hyper-methylated PCa|NT DMRschr10 126678095 126683437 0.005968871 −36.06296296 Hypo-methylatedPCa|NT DMRs chr10 126686860 126690570 2.24E−06 −25.75517241Hypo-methylated PCa|NT DMRs chr10 126812260 126823549 0.000751352−35.7070028 Hypo-methylated PCa|NT DMRs chr10 126850914 1268511308.96E−05 35.29761905 Hyper-methylated PCa|NT DMRs chr10 127050542127059592 0.005601663 21.05569358 Hyper-methylated PCa|NT DMRs chr10127462344 127462851 1.69E−13 23.84531746 Hyper-methylated PCa|NT DMRschr10 127914914 127938198 1.03E−05 −30.49722222 Hypo-methylated PCa|NTDMRs chr10 128077288 128077792 5.62E−06 33.77931034 Hyper-methylatedPCa|NT DMRs chr10 129733149 129733592 0.001139334 25.3281746Hyper-methylated PCa|NT DMRs chr10 129770270 129790276 0.00111671921.9562212 Hyper-methylated PCa|NT DMRs chr10 129858596 1298645710.002233556 23.72704082 Hyper-methylated PCa|NT DMRs chr10 130020722130020924 0.00064571  −41.18367347 Hypo-methylated PCa|NT DMRs chr10130064035 130064194 0.00179283  20.86147186 Hyper-methylated PCa|NT DMRschr10 130084659 130085481 3.29E−07 20.1031746 Hyper-methylated PCa|NTDMRs chr10 130278887 130280004 2.49E−06 −33.42162698 Hypo-methylatedPCa|NT DMRs chr10 130482299 130489627 0.002437742 −21.74232804Hypo-methylated PCa|NT DMRs chr10 130594618 130600266 0.005968871−38.6047619 Hypo-methylated PCa|NT DMRs chr10 130832358 1308324195.84E−05 32.72619048 Hyper-methylated PCa|NT DMRs chr10 131193314131194474 0.000200126 −24.43772894 Hypo-methylated PCa|NT DMRs chr10131506200 131506279 0.005968871 −58.62857143 Hypo-methylated PCa|NT DMRschr10 131755588 131758298 1.32E−38 22.04497354 Hyper-methylated PCa|NTDMRs chr10 131826134 131826673 0.003448944 −38.38367347 Hypo-methylatedPCa|NT DMRs chr10 131861385 131861677 0.000188936 −25.50595238Hypo-methylated PCa|NT DMRs chr10 132019960 132020489 0.000118733−44.65873016 Hypo-methylated PCa|NT DMRs chr10 132119797 1321288220.001083007 −20.78031746 Hypo-methylated PCa|NT DMRs chr10 132154720132162308 0.000815653 −26.23730159 Hypo-methylated PCa|NT DMRs chr10132177762 132308583 8.20E−23 −24.79236948 Hypo-methylated PCa|NT DMRschr10 132329756 132365705 6.88E−13 −23.28377425 Hypo-methylated PCa|NTDMRs chr10 132448255 132452879 1.67E−05 −34.06547619 Hypo-methylatedPCa|NT DMRs chr10 132464783 132488867 0.002433478 −30.73809524Hypo-methylated PCa|NT DMRs chr10 132539506 132560543 3.12E−08−28.05044092 Hypo-methylated PCa|NT DMRs chr10 132818102 1328472077.98E−14 −28.92063492 Hypo-methylated PCa|NT DMRs chr10 132883449132883666 0.00064571  30.20068027 Hyper-methylated PCa|NT DMRs chr10133058588 133070062 3.81E−05 −22.45378151 Hypo-methylated PCa|NT DMRschr10 133357723 133454857 1.86E−26 −29.24356553 Hypo-methylated PCa|NTDMRs chr10 133476648 133521931 3.23E−15 −27.00648926 Hypo-methylatedPCa|NT DMRs chr10 133619180 133635888 0.003578734 −23.26834734Hypo-methylated PCa|NT DMRs chr10 133638698 133737519 9.08E−22−24.98830409 Hypo-methylated PCa|NT DMRs chr10 133837293 1338373480.000377317 −30.51785714 Hypo-methylated PCa|NT DMRs chr10 133861842133861990 0.001969641 −48.38095238 Hypo-methylated PCa|NT DMRs chr10133890732 133892633 8.30E−06 24.84970238 Hyper-methylated PCa|NT DMRschr10 133946539 133946882 0.000810017 −22.04389234 Hypo-methylatedPCa|NT DMRs chr10 134001067 134002033 1.51E−09 24.50027473Hyper-methylated PCa|NT DMRs chr10 134063331 134063676 0.00057238522.51666667 Hyper-methylated PCa|NT DMRs chr10 134079332 1340794790.00064571  −53.9122449 Hypo-methylated PCa|NT DMRs chr10 134107089134107362 0.001083007 −45.15952381 Hypo-methylated PCa|NT DMRs chr10134220460 134226000 0.000128082 −28.495671 Hypo-methylated PCa|NT DMRschr10 134256135 134262212 1.99E−05 26.84824798 Hyper-methylated PCa|NTDMRs chr10 134310933 134311115 0.00064571  38.84013605 Hyper-methylatedPCa|NT DMRs chr10 134331048 134331115 0.005968871 20.71428571Hyper-methylated PCa|NT DMRs chr10 134331816 134332730 0.001175696−21.54089636 Hypo-methylated PCa|NT DMRs chr10 134392611 1343929842.75E−05 25.68941799 Hyper-methylated PCa|NT DMRs chr10 134499085134499409 1.42E−05 −54.55952381 Hypo-methylated PCa|NT DMRs chr10134577650 134578521 0.000572385 −35.34880952 Hypo-methylated PCa|NT DMRschr10 134772885 134774108 3.98E−06 −30.56340852 Hypo-methylated PCa|NTDMRs chr10 135071741 135074493 0.000163436 29.90833333 Hyper-methylatedPCa|NT DMRs chr10 135087840 135090821 3.60E−19 31.87207792Hyper-methylated PCa|NT DMRs chr10 135148215 135148379 0.00569382 25.25142857 Hyper-methylated PCa|NT DMRs chr10 135170769 1351715249.80E−21 21.35485714 Hyper-methylated PCa|NT DMRs chr10 135173233135174232 3.44E−06 −50.9360119 Hypo-methylated PCa|NT DMRs chr10135177818 135186510 2.49E−06 −27.24642857 Hypo-methylated PCa|NT DMRschr10 135193212 135193966 2.31E−05 −21.26380952 Hypo-methylated PCa|NTDMRs chr10 135202490 135205539 0.000205174 33.59642857 Hyper-methylatedPCa|NT DMRs chr10 135278717 135279026 5.45E−08 20.90742297Hyper-methylated PCa|NT DMRs chr11 189759 197036 1.04E−05 −26.84285714Hypo-methylated PCa|NT DMRs chr11 296220 300915 2.83E−07 −21.22723475Hypo-methylated PCa|NT DMRs chr11 326026 326953 0.001076343 32.65367965Hyper-methylated PCa|NT DMRs chr11 355557 355907 0.001129594 21.96938776Hyper-methylated PCa|NT DMRs chr11 381303 382928 2.50E−05 32.16513057Hyper-methylated PCa|NT DMRs chr11 391004 391323 0.007679542−22.96938776 Hypo-methylated PCa|NT DMRs chr11 409751 410268 2.03E−06−41.08 Hypo-methylated PCa|NT DMRs chr11 415120 416269 5.87E−0847.19690476 Hyper-methylated PCa|NT DMRs chr11 428780 430335 0.000284668−20.79029304 Hypo-methylated PCa|NT DMRs chr11 438565 438623 0.003400006−27.17006803 Hypo-methylated PCa|NT DMRs chr11 457304 457482 0.00064571 46.06122449 Hyper-methylated PCa|NT DMRs chr11 468308 471390 2.42E−05−27.13250518 Hypo-methylated PCa|NT DMRs chr11 518565 518649 5.94E−06−39.21038961 Hypo-methylated PCa|NT DMRs chr11 569079 569585 0.00019065828.39350649 Hyper-methylated PCa|NT DMRs chr11 611583 613053 4.56E−05−22.07142857 Hypo-methylated PCa|NT DMRs chr11 613978 615335 2.66E−11−42.66214896 Hypo-methylated PCa|NT DMRs chr11 637015 637876 4.60E−1320.09545788 Hyper-methylated PCa|NT DMRs chr11 696745 706044 5.21E−05−27.78036929 Hypo-methylated PCa|NT DMRs chr11 772670 773252 0.003583021−23.78888889 Hypo-methylated PCa|NT DMRs chr11 782976 783617 0.000146826−34.75214286 Hypo-methylated PCa|NT DMRs chr11 787739 788443 0.00156288322.08979592 Hyper-methylated PCa|NT DMRs chr11 794755 795583 6.43E−05−21.10294785 Hypo-methylated PCa|NT DMRs chr11 823706 826239 1.13E−15−49.31398176 Hypo-methylated PCa|NT DMRs chr11 840291 841636 0.001015461−22.35714286 Hypo-methylated PCa|NT DMRs chr11 850196 851049 3.78E−06−30.76210317 Hypo-methylated PCa|NT DMRs chr11 858671 862859 7.72E−13−28.12434457 Hypo-methylated PCa|NT DMRs chr11 925384 925430 0.00196964133.80952381 Hyper-methylated PCa|NT DMRs chr11 968922 971653 0.00369429428.91575092 Hyper-methylated PCa|NT DMRs chr11 1029129 1030777 5.90E−07−23.60426587 Hypo-methylated PCa|NT DMRs chr11 1041355 10422590.002803541 −30.13730159 Hypo-methylated PCa|NT DMRs chr11 10438861043952 6.42E−05 −45.79365079 Hypo-methylated PCa|NT DMRs chr11 10528801055266 3.70E−06 −36.09137709 Hypo-methylated PCa|NT DMRs chr11 10795671079809 0.000354065 −33.6968254 Hypo-methylated PCa|NT DMRs chr111081684 1081848 5.52E−05 −36.48051948 Hypo-methylated PCa|NT DMRs chr111084299 1084406 0.000481535 −22.27777778 Hypo-methylated PCa|NT DMRschr11 1145197 1146854 3.86E−10 41.59300595 Hyper-methylated PCa|NT DMRschr11 1216195 1216973 0.000344011 −26.61176471 Hypo-methylated PCa|NTDMRs chr11 1217280 1219755 7.06E−12 −22.22213868 Hypo-methylated PCa|NTDMRs chr11 1241256 1241568 0.001800067 −21.88958333 Hypo-methylatedPCa|NT DMRs chr11 1243817 1245364 3.77E−05 −27.95142857 Hypo-methylatedPCa|NT DMRs chr11 1260215 1260592 0.000392715 −33.91714286Hypo-methylated PCa|NT DMRs chr11 1270339 1271077 0.000205174−30.27380952 Hypo-methylated PCa|NT DMRs chr11 1331419 13316360.000251944 −20.1443609 Hypo-methylated PCa|NT DMRs chr11 13320161332394 0.000858283 52.56493506 Hyper-methylated PCa|NT DMRs chr111358178 1358819 1.16E−22 23.79791332 Hyper-methylated PCa|NT DMRs chr111361518 1365001 0.003314163 −30.60095238 Hypo-methylated PCa|NT DMRschr11 1375302 1375865 2.37E−05 −24.1047619 Hypo-methylated PCa|NT DMRschr11 1409935 1410134 0.000974795 32.70595238 Hyper-methylated PCa|NTDMRs chr11 1412450 1412572 0.000377317 20.80952381 Hyper-methylatedPCa|NT DMRs chr11 1427510 1437123 0.000157373 −24.1021164Hypo-methylated PCa|NT DMRs chr11 1455363 1455574 0.000632596−43.42857143 Hypo-methylated PCa|NT DMRs chr11 1470285 14703670.000172237 41.48571429 Hyper-methylated PCa|NT DMRs chr11 15071591508462 0.000164894 −22.0543514 Hypo-methylated PCa|NT DMRs chr111524032 1524769 0.006407159 −28.95670996 Hypo-methylated PCa|NT DMRschr11 1536165 1537082 0.005955401 −24.87359307 Hypo-methylated PCa|NTDMRs chr11 1568900 1569417 5.19E−07 26.61527778 Hyper-methylated PCa|NTDMRs chr11 1577228 1578737 4.17E−16 38.94197802 Hyper-methylated PCa|NTDMRs chr11 1591405 1592675 0.007403789 20.15892857 Hyper-methylatedPCa|NT DMRs chr11 1629694 1644607 0.000392715 −23.14714286Hypo-methylated PCa|NT DMRs chr11 1662582 1664538 3.36E−06 −28.01014493Hypo-methylated PCa|NT DMRs chr11 1665947 1666155 5.94E−06 −31.73593074Hypo-methylated PCa|NT DMRs chr11 1687822 1705621 1.57E−07 −21.01428571Hypo-methylated PCa|NT DMRs chr11 1749330 1766467 1.26E−05 −28.90062657Hypo-methylated PCa|NT DMRs chr11 1767793 1768079 0.00016931621.58730159 Hyper-methylated PCa|NT DMRs chr11 1772276 1776901 6.85E−0720.82103767 Hyper-methylated PCa|NT DMRs chr11 1778046 1782746 1.49E−1122.96197279 Hyper-methylated PCa|NT DMRs chr11 1802030 18024360.00064571  36.64285714 Hyper-methylated PCa|NT DMRs chr11 18463751846611 0.003448944 33.84798535 Hyper-methylated PCa|NT DMRs chr111879145 1879521 0.000205174 −27.19642857 Hypo-methylated PCa|NT DMRschr11 1884626 1886444 3.46E−05 −33.72914286 Hypo-methylated PCa|NT DMRschr11 1909030 1918969 5.47E−13 34.57640693 Hyper-methylated PCa|NT DMRschr11 1987847 1990174 7.32E−07 −20.57021792 Hypo-methylated PCa|NT DMRschr11 1991933 1992320 0.00013778  −20.83333333 Hypo-methylated PCa|NTDMRs chr11 1994362 1995123 3.02E−06 −24.99821429 Hypo-methylated PCa|NTDMRs chr11 2060636 2092371 0.00068166  −20.92916667 Hypo-methylatedPCa|NT DMRs chr11 2118862 2119159 0.001310211 −26.58571429Hypo-methylated PCa|NT DMRs chr11 2143574 2144335 3.77E−05 −29.34223602Hypo-methylated PCa|NT DMRs chr11 2214934 2215334 0.000176268−20.38235294 Hypo-methylated PCa|NT DMRs chr11 2223474 22236620.007959104 −35.00544218 Hypo-methylated PCa|NT DMRs chr11 22784492278938 4.89E−08 −49.65909091 Hypo-methylated PCa|NT DMRs chr11 23106832320775 0.007526322 −23.01071429 Hypo-methylated PCa|NT DMRs chr112321699 2324965 0.002211645 33.88278388 Hyper-methylated PCa|NT DMRschr11 2329041 2329457 0.005968871 −27.06190476 Hypo-methylated PCa|NTDMRs chr11 2397303 2397774 6.69E−05 −48.85238095 Hypo-methylated PCa|NTDMRs chr11 2425925 2428586 6.80E−09 −34.86359447 Hypo-methylated PCa|NTDMRs chr11 2443237 2448964 4.16E−09 −20.57718254 Hypo-methylated PCa|NTDMRs chr11 2487303 2488886 0.000715461 31.28571429 Hyper-methylatedPCa|NT DMRs chr11 2554914 2555248 2.86E−05 49.56043956 Hyper-methylatedPCa|NT DMRs chr11 2769117 2769207 0.005118278 22.6984127Hyper-methylated PCa|NT DMRs chr11 2795863 2799884 0.00027884322.31587302 Hyper-methylated PCa|NT DMRs chr11 2801145 2810152 4.05E−0740.71005291 Hyper-methylated PCa|NT DMRs chr11 2847158 2849208 1.16E−0539.02689076 Hyper-methylated PCa|NT DMRs chr11 2859574 28599340.001699622 22.03736264 Hyper-methylated PCa|NT DMRs chr11 28609692862483 0.001850915 −37.5952381 Hypo-methylated PCa|NT DMRs chr112870712 2871458 0.001452156 −26.44867725 Hypo-methylated PCa|NT DMRschr11 2905051 2905522 7.59E−10 23.59047619 Hyper-methylated PCa|NT DMRschr11 2911274 2912409 5.46E−05 −38.56190476 Hypo-methylated PCa|NT DMRschr11 2952174 2952440 0.004886033 −34.68681319 Hypo-methylated PCa|NTDMRs chr11 3104576 3104685 0.000354065 34.74973545 Hyper-methylatedPCa|NT DMRs chr11 3236759 3237763 0.000354065 −36.81904762Hypo-methylated PCa|NT DMRs chr11 3241803 3243314 2.01E−05 −26.47904762Hypo-methylated PCa|NT DMRs chr11 3244384 3244487 0.00403792928.75986395 Hyper-methylated PCa|NT DMRs chr11 3245602 32464170.000122432 −20.97402597 Hypo-methylated PCa|NT DMRs chr11 34979273498254 1.97E−05 −50.68095238 Hypo-methylated PCa|NT DMRs chr11 42333654233428 6.42E−05 32.06402116 Hyper-methylated PCa|NT DMRs chr11 63404466341909 9.20E−08 30.52438095 Hyper-methylated PCa|NT DMRs chr11 67184976938263 8.59E−05 −24.72494331 Hypo-methylated PCa|NT DMRs chr11 73317637404387 0.000215808 −25.83809524 Hypo-methylated PCa|NT DMRs chr118378642 8378865 5.94E−06 −26.15844156 Hypo-methylated PCa|NT DMRs chr118737118 8737725 0.000279449 36.84835165 Hyper-methylated PCa|NT DMRschr11 8743062 8743397 0.005968871 −47.28571429 Hypo-methylated PCa|NTDMRs chr11 9112531 9115613 3.14E−16 23.1922619 Hyper-methylated PCa|NTDMRs chr11 9352573 9352746 0.005968871 −21.94285714 Hypo-methylatedPCa|NT DMRs chr11 9761857 9762057 0.005968871 −48.02380952Hypo-methylated PCa|NT DMRs chr11 9780693 9780891 0.00175692627.67532468 Hyper-methylated PCa|NT DMRs chr11 10373208 103741170.000513415 −30.88265306 Hypo-methylated PCa|NT DMRs chr11 1047782110481018 0.002822916 29.07738095 Hyper-methylated PCa|NT DMRs chr1110696385 10696570 0.001969641 32.70408163 Hyper-methylated PCa|NT DMRschr11 11577882 11577963 0.00064571  20.2244898 Hyper-methylated PCa|NTDMRs chr11 11602473 11602883 0.00064571  −55.06530612 Hypo-methylatedPCa|NT DMRs chr11 12133006 12147266 0.000457395 −27.72710623Hypo-methylated PCa|NT DMRs chr11 12246231 12246580 0.00209719347.28571429 Hyper-methylated PCa|NT DMRs chr11 13259400 132601650.001241245 −21.4984127 Hypo-methylated PCa|NT DMRs chr11 1401414614099328 0.004960253 −24.18190476 Hypo-methylated PCa|NT DMRs chr1114444083 14445441 0.005968871 42.85714286 Hyper-methylated PCa|NT DMRschr11 15672498 15672803 2.86E−05 39.82234432 Hyper-methylated PCa|NTDMRs chr11 16812592 16812647 0.00023371  27.34761905 Hyper-methylatedPCa|NT DMRs chr11 17034484 17034890 0.001795658 −20.67965368Hypo-methylated PCa|NT DMRs chr11 17497511 17497842 6.02E−06 27.45804989Hyper-methylated PCa|NT DMRs chr11 17610719 17613146 2.86E−07−24.91836735 Hypo-methylated PCa|NT DMRs chr11 18067693 180678981.66E−10 20.13095238 Hyper-methylated PCa|NT DMRs chr11 1841509518415164 0.005968871 45.14285714 Hyper-methylated PCa|NT DMRs chr1118660236 18690509 0.002463549 −20.83201058 Hypo-methylated PCa|NT DMRschr11 18814124 18814307 0.000377317 31.57738095 Hyper-methylated PCa|NTDMRs chr11 19331335 19366473 0.004553481 −32.04497354 Hypo-methylatedPCa|NT DMRs chr11 19799412 19799663 0.001042833 22.07380952Hyper-methylated PCa|NT DMRs chr11 20234715 20339377 8.58E−07−34.75694444 Hypo-methylated PCa|NT DMRs chr11 21920677 221636873.43E−06 −28.15416667 Hypo-methylated PCa|NT DMRs chr11 2247381122623620 0.001241245 −34.38498168 Hypo-methylated PCa|NT DMRs chr1129105863 29849310 3.26E−12 −30.26559524 Hypo-methylated PCa|NT DMRschr11 31915052 32005742 0.00046742  −28.36147186 Hypo-methylated PCa|NTDMRs chr11 32022513 32052791 0.005968871 −39.17047619 Hypo-methylatedPCa|NT DMRs chr11 32915068 32915702 2.15E−12 23.46084656Hyper-methylated PCa|NT DMRs chr11 33471349 33526406 0.004553481−23.48730159 Hypo-methylated PCa|NT DMRs chr11 33677736 337188781.04E−05 −21.64536341 Hypo-methylated PCa|NT DMRs chr11 3372059333722029 7.03E−07 33.94659864 Hyper-methylated PCa|NT DMRs chr1133840720 33843290 0.000974795 −23.17857143 Hypo-methylated PCa|NT DMRschr11 33850491 33850706 0.002467228 20.79285714 Hyper-methylated PCa|NTDMRs chr11 33890313 33890427 0.000377317 26.80357143 Hyper-methylatedPCa|NT DMRs chr11 34176919 34177143 0.000477661 −42.79365079Hypo-methylated PCa|NT DMRs chr11 34190768 34191182 0.007338757−54.99047619 Hypo-methylated PCa|NT DMRs chr11 35327601 353277490.001907648 23.26190476 Hyper-methylated PCa|NT DMRs chr11 3544133235442136 4.32E−16 36.50096852 Hyper-methylated PCa|NT DMRs chr1136145373 36145511 0.008482405 −62.08571429 Hypo-methylated PCa|NT DMRschr11 36397568 36397612 0.005968871 44.03333333 Hyper-methylated PCa|NTDMRs chr11 38300432 38470399 1.42E−09 −21.30297619 Hypo-methylatedPCa|NT DMRs chr11 38609186 38656021 0.001111028 −34.76984127Hypo-methylated PCa|NT DMRs chr11 39471249 40201149 1.34E−24−30.77926587 Hypo-methylated PCa|NT DMRs chr11 43602594 436049093.38E−14 20.64880952 Hyper-methylated PCa|NT DMRs chr11 4454179544542054 3.11E−06 20.23714286 Hyper-methylated PCa|NT DMRs chr1144814303 44833307 0.008234951 −23.04761905 Hypo-methylated PCa|NT DMRschr11 44840127 44865219 1.16E−06 −26.09077381 Hypo-methylated PCa|NTDMRs chr11 44948290 44951493 0.000715461 −23.2202381 Hypo-methylatedPCa|NT DMRs chr11 44960769 44961736 5.50E−07 26.83503401Hyper-methylated PCa|NT DMRs chr11 45101759 45102447 0.00196964148.71428571 Hyper-methylated PCa|NT DMRs chr11 45182876 451847430.00601179  −24.23904762 Hypo-methylated PCa|NT DMRs chr11 4544639345467192 0.00064571  −34.62857143 Hypo-methylated PCa|NT DMRs chr1145685821 45685918 0.005968871 41.71238095 Hyper-methylated PCa|NT DMRschr11 45907522 45908075 0.002879175 21.08739496 Hyper-methylated PCa|NTDMRs chr11 45943130 45943839 3.45E−14 −34.64606227 Hypo-methylatedPCa|NT DMRs chr11 46366989 46367974 0.005968871 60.26190476Hyper-methylated PCa|NT DMRs chr11 46372695 46384984 0.00021751 23.60044297 Hyper-methylated PCa|NT DMRs chr11 46564148 465643440.007560755 −22.46011905 Hypo-methylated PCa|NT DMRs chr11 4720652347207567 4.03E−05 −23.77960928 Hypo-methylated PCa|NT DMRs chr1147208766 47214114 0.000196134 31.24952381 Hyper-methylated PCa|NT DMRschr11 47214207 47215955 0.003892841 −30.33862434 Hypo-methylated PCa|NTDMRs chr11 47279157 47289256 0.000185736 25.37637363 Hyper-methylatedPCa|NT DMRs chr11 47376715 47380422 9.33E−05 −45.89047619Hypo-methylated PCa|NT DMRs chr11 47396170 47417596 1.56E−22 42.33257576Hyper-methylated PCa|NT DMRs chr11 47609825 47609937 0.00596887149.96571429 Hyper-methylated PCa|NT DMRs chr11 48012330 480123790.008482405 −27 Hypo-methylated PCa|NT DMRs chr11 48023591 480570120.002885118 25.25380952 Hyper-methylated PCa|NT DMRs chr11 4810184848103102 8.94E−05 22.56255411 Hyper-methylated PCa|NT DMRs chr1149031974 49069341 0.005968871 −24.81428571 Hypo-methylated PCa|NT DMRschr11 49455099 49455940 0.001115302 −31.80119048 Hypo-methylated PCa|NTDMRs chr11 49912911 49913484 0.000847246 −30.07582418 Hypo-methylatedPCa|NT DMRs chr11 49915274 50180943 3.56E−12 −31.34031746Hypo-methylated PCa|NT DMRs chr11 50221563 50257289 1.08E−14−28.44088889 Hypo-methylated PCa|NT DMRs chr11 56557728 568004162.33E−12 −32.24821429 Hypo-methylated PCa|NT DMRs chr11 5714764057182673 1.50E−05 −23.68035714 Hypo-methylated PCa|NT DMRs chr1157225287 57225426 0.001969641 34.08843537 Hyper-methylated PCa|NT DMRschr11 57235346 57235492 6.94E−06 −59.11428571 Hypo-methylated PCa|NTDMRs chr11 57478704 57478950 0.00179283  −28.93452381 Hypo-methylatedPCa|NT DMRs chr11 58376323 58377458 0.00329109  37.36363636Hyper-methylated PCa|NT DMRs chr11 58429215 58442218 0.001896858−32.34920635 Hypo-methylated PCa|NT DMRs chr11 58940671 589409130.004095673 45.96507937 Hyper-methylated PCa|NT DMRs chr11 5922127559278014 1.42E−05 −35.71142857 Hypo-methylated PCa|NT DMRs chr1159323338 59324098 0.001674516 21.28515406 Hyper-methylated PCa|NT DMRschr11 59333340 59333864 4.96E−09 24.12315271 Hyper-methylated PCa|NTDMRs chr11 59478100 59520668 0.000205174 −30.61785714 Hypo-methylatedPCa|NT DMRs chr11 59968481 60105291 1.84E−08 −28.66897547Hypo-methylated PCa|NT DMRs chr11 60534949 60535138 0.00889713923.62337662 Hyper-methylated PCa|NT DMRs chr11 60778547 607797050.002433478 39.3077381 Hyper-methylated PCa|NT DMRs chr11 6086996960887659 0.001083007 23.42142857 Hyper-methylated PCa|NT DMRs chr1161049111 61049231 0.003689112 −21.97362637 Hypo-methylated PCa|NT DMRschr11 61109959 61110130 0.00641359  35.83333333 Hyper-methylated PCa|NTDMRs chr11 61256187 61257657 0.00064571  −50.74829932 Hypo-methylatedPCa|NT DMRs chr11 61343520 61344277 0.000137816 −53.59325397Hypo-methylated PCa|NT DMRs chr11 61375495 61378730 0.00064571 −40.92176871 Hypo-methylated PCa|NT DMRs chr11 61394328 613945370.005968871 −41.46190476 Hypo-methylated PCa|NT DMRs chr11 6145151261452306 0.00064571  44.40816327 Hyper-methylated PCa|NT DMRs chr1161593787 61595285 0.004677148 26.17359307 Hyper-methylated PCa|NT DMRschr11 61596960 61600845 0.002802605 −28.63265306 Hypo-methylated PCa|NTDMRs chr11 61671833 61672078 0.005968871 46.6047619 Hyper-methylatedPCa|NT DMRs chr11 62273922 62277677 0.005968871 −23.46137566Hypo-methylated PCa|NT DMRs chr11 62380679 62381007 0.005438982−32.15714286 Hypo-methylated PCa|NT DMRs chr11 62447157 624493780.000205174 −32.23511905 Hypo-methylated PCa|NT DMRs chr11 6255585762558534 0.001013662 −25.80748299 Hypo-methylated PCa|NT DMRs chr1162609849 62610107 0.000209486 29.82603175 Hyper-methylated PCa|NT DMRschr11 62673739 62677297 0.000150833 −30.52933333 Hypo-methylated PCa|NTDMRs chr11 62677889 62678152 6.42E−05 −26.6005291 Hypo-methylated PCa|NTDMRs chr11 62689065 62689123 0.008482405 −37.97142857 Hypo-methylatedPCa|NT DMRs chr11 63257599 63278917 1.53E−05 31.75038402Hyper-methylated PCa|NT DMRs chr11 63529502 63531940 7.77E−35−22.27085485 Hypo-methylated PCa|NT DMRs chr11 63608634 636099300.001969641 −50.69047619 Hypo-methylated PCa|NT DMRs chr11 6376631663766738 1.02E−05 32.27928571 Hyper-methylated PCa|NT DMRs chr1163768254 63775073 3.87E−06 23.51582418 Hyper-methylated PCa|NT DMRschr11 63802060 63802461 0.003448944 30.15306122 Hyper-methylated PCa|NTDMRs chr11 63913750 63913964 0.002437742 29.96031746 Hyper-methylatedPCa|NT DMRs chr11 63932230 63932757 0.000205174 −43.78571429Hypo-methylated PCa|NT DMRs chr11 63972859 63978501 8.22E−09 34.14940476Hyper-methylated PCa|NT DMRs chr11 64069092 64069339 0.00569382 −22.89285714 Hypo-methylated PCa|NT DMRs chr11 64074084 640741660.000205174 35.61488095 Hyper-methylated PCa|NT DMRs chr11 6416295464167498 0.000191452 32.52380952 Hyper-methylated PCa|NT DMRs chr1164177216 64177389 0.005968871 39.68571429 Hyper-methylated PCa|NT DMRschr11 64375615 64375708 0.001969641 −54.82585034 Hypo-methylated PCa|NTDMRs chr11 64478990 64479058 0.00064571  36.39047619 Hyper-methylatedPCa|NT DMRs chr11 64480312 64480500 4.20E−06 22.25396825Hyper-methylated PCa|NT DMRs chr11 64609864 64611748 0.000357945−36.87751323 Hypo-methylated PCa|NT DMRs chr11 64618782 646305858.36E−09 35.07356657 Hyper-methylated PCa|NT DMRs chr11 6463270564643976 1.94E−10 27.76675325 Hyper-methylated PCa|NT DMRs chr1164659028 64659131 0.001181579 −29.93877551 Hypo-methylated PCa|NT DMRschr11 64660850 64662239 0.004505524 28.50992063 Hyper-methylated PCa|NTDMRs chr11 64706819 64721931 0.006589535 −22.43095238 Hypo-methylatedPCa|NT DMRs chr11 64757720 64758048 0.00064571  39.58367347Hyper-methylated PCa|NT DMRs chr11 65006862 65010385 0.002534928 −24.63Hypo-methylated PCa|NT DMRs chr11 65145930 65146458 0.00795910436.91020408 Hyper-methylated PCa|NT DMRs chr11 65307124 653074091.89E−05 −24.24920635 Hypo-methylated PCa|NT DMRs chr11 6541427365415386 1.03E−17 −47.82563025 Hypo-methylated PCa|NT DMRs chr1165459968 65460448 0.003448944 −36.27891156 Hypo-methylated PCa|NT DMRschr11 65549119 65549225 0.006589535 22.51428571 Hyper-methylated PCa|NTDMRs chr11 65553636 65553876 0.00020505  25.20017637 Hyper-methylatedPCa|NT DMRs chr11 65560596 65560988 0.000111427 −39.68238095Hypo-methylated PCa|NT DMRs chr11 65658854 65667189 8.33E−17 24.46147959Hyper-methylated PCa|NT DMRs chr11 65707163 65727355 1.35E−10−22.94155844 Hypo-methylated PCa|NT DMRs chr11 65790280 657907210.009165255 −23.08280423 Hypo-methylated PCa|NT DMRs chr11 6608430666084895 3.51E−06 23.40119048 Hyper-methylated PCa|NT DMRs chr1166179672 66179920 0.001896858 −37.58730159 Hypo-methylated PCa|NT DMRschr11 66326554 66327126 0.000157858 20.08050595 Hyper-methylated PCa|NTDMRs chr11 66484890 66486141 3.90E−08 −50.18178054 Hypo-methylatedPCa|NT DMRs chr11 66816488 66816867 0.00641359  29.3968254Hyper-methylated PCa|NT DMRs chr11 67043561 67046287 0.00022667130.1377425 Hyper-methylated PCa|NT DMRs chr11 67049199 67054945 7.34E−1230.2312256 Hyper-methylated PCa|NT DMRs chr11 67164636 671647890.00064571  47.26870748 Hyper-methylated PCa|NT DMRs chr11 6717101567173367 6.94E−06 34.78027211 Hyper-methylated PCa|NT DMRs chr1167176301 67177283 2.72E−07 33.35714286 Hyper-methylated PCa|NT DMRschr11 67178868 67179368 0.000320751 −20.01587302 Hypo-methylated PCa|NTDMRs chr11 67204882 67206343 0.000728857 33.8707483 Hyper-methylatedPCa|NT DMRs chr11 67210077 67210845 2.98E−06 −36.78280423Hypo-methylated PCa|NT DMRs chr11 67219498 67220021 0.000145907−38.95142857 Hypo-methylated PCa|NT DMRs chr11 67345075 673493750.004535472 −31.39821429 Hypo-methylated PCa|NT DMRs chr11 6773348967746317 0.001139334 −37.53809524 Hypo-methylated PCa|NT DMRs chr1167770789 67770905 5.52E−05 31.51948052 Hyper-methylated PCa|NT DMRschr11 67778480 67778837 1.76E−06 44.68809524 Hyper-methylated PCa|NTDMRs chr11 67786698 67788233 0.007679542 −33.98677249 Hypo-methylatedPCa|NT DMRs chr11 67803806 67804652 0.000100211 37.76666667Hyper-methylated PCa|NT DMRs chr11 68049738 68050189 0.00064571 50.56802721 Hyper-methylated PCa|NT DMRs chr11 68064507 680649525.42E−05 −33.91468254 Hypo-methylated PCa|NT DMRs chr11 6806564468066064 0.001789867 −35.15925926 Hypo-methylated PCa|NT DMRs chr1168066301 68076037 0.000611234 24.33746032 Hyper-methylated PCa|NT DMRschr11 68098668 68098999 0.000122432 40.73593074 Hyper-methylated PCa|NTDMRs chr11 68173861 68176237 0.000205174 −53.81011905 Hypo-methylatedPCa|NT DMRs chr11 68207094 68207415 0.000424462 −23.92517007Hypo-methylated PCa|NT DMRs chr11 68419149 68419629 0.00170819 −31.21428571 Hypo-methylated PCa|NT DMRs chr11 68452595 684526852.18E−05 24.58319328 Hyper-methylated PCa|NT DMRs chr11 6853010468532038 0.000339757 26.19345238 Hyper-methylated PCa|NT DMRs chr1168534208 68534505 0.00064571  39.08163265 Hyper-methylated PCa|NT DMRschr11 68592697 68597846 0.002931637 28.44057143 Hyper-methylated PCa|NTDMRs chr11 68621969 68627789 2.62E−09 26.04550265 Hyper-methylatedPCa|NT DMRs chr11 68637018 68638340 1.07E−06 31.25192744Hyper-methylated PCa|NT DMRs chr11 68639648 68643065 0.000205174−38.37797619 Hypo-methylated PCa|NT DMRs chr11 68701326 687022920.00064571  −21.29931973 Hypo-methylated PCa|NT DMRs chr11 6886467768867966 0.002675664 23.68696742 Hyper-methylated PCa|NT DMRs chr1168890034 68890407 0.002641501 −25.69047619 Hypo-methylated PCa|NT DMRschr11 68924647 68925108 7.75E−10 22.57777778 Hyper-methylated PCa|NTDMRs chr11 68963501 68963776 0.000112123 −25.93253968 Hypo-methylatedPCa|NT DMRs chr11 69019266 69024680 0.000822388 −27.11688312Hypo-methylated PCa|NT DMRs chr11 69045416 69045825 0.001969641−46.81088435 Hypo-methylated PCa|NT DMRs chr11 69189180 691896366.21E−05 37.60714286 Hyper-methylated PCa|NT DMRs chr11 6919313469193688 0.000457395 −27.12527473 Hypo-methylated PCa|NT DMRs chr1169229729 69230044 0.001969641 35.5952381 Hyper-methylated PCa|NT DMRschr11 69258282 69258722 8.37E−10 32.54530612 Hyper-methylated PCa|NTDMRs chr11 69276968 69280578 9.48E−07 −26.25192012 Hypo-methylatedPCa|NT DMRs chr11 69285805 69286585 0.000186814 23.43142857Hyper-methylated PCa|NT DMRs chr11 69311990 69312363 1.76E−06−27.34798535 Hypo-methylated PCa|NT DMRs chr11 69339369 693396060.005513661 −29.86666667 Hypo-methylated PCa|NT DMRs chr11 6945855269461852 0.000549692 −21.71390977 Hypo-methylated PCa|NT DMRs chr1169465895 69470244 5.64E−06 −38.13984962 Hypo-methylated PCa|NT DMRschr11 69520931 69527291 3.67E−06 27.4247619 Hyper-methylated PCa|NT DMRschr11 69677205 69677632 0.000117699 23.07744361 Hyper-methylated PCa|NTDMRs chr11 69683075 69683462 5.18E−06 26.80910973 Hyper-methylatedPCa|NT DMRs chr11 69707569 69707837 0.005968871 48.98761905Hyper-methylated PCa|NT DMRs chr11 69832153 69832553 5.30E−0920.07053571 Hyper-methylated PCa|NT DMRs chr11 69949556 699500830.00068166  −35.39880952 Hypo-methylated PCa|NT DMRs chr11 7004391470048550 0.005968871 −21.88359788 Hypo-methylated PCa|NT DMRs chr1170261857 70261911 0.00023371  55.32619048 Hyper-methylated PCa|NT DMRschr11 70278186 70278327 0.009924186 35.44973545 Hyper-methylated PCa|NTDMRs chr11 70282413 70283318 7.27E−06 −36.51407867 Hypo-methylatedPCa|NT DMRs chr11 70713938 70714173 0.000118733 −23.89365079Hypo-methylated PCa|NT DMRs chr11 71189249 71191381 0.00723957721.99365079 Hyper-methylated PCa|NT DMRs chr11 71326126 713485249.46E−05 −33.13378685 Hypo-methylated PCa|NT DMRs chr11 7179228871792393 0.00064571  −29.05714286 Hypo-methylated PCa|NT DMRs chr1172328987 72330016 0.000377317 −21.1577381 Hypo-methylated PCa|NT DMRschr11 72336639 72337206 0.001443483 −25.88004535 Hypo-methylated PCa|NTDMRs chr11 72527551 72528765 0.002097193 48.61292517 Hyper-methylatedPCa|NT DMRs chr11 72532653 72533479 5.58E−16 −37.86146384Hypo-methylated PCa|NT DMRs chr11 72915848 72917050 6.42E−05 51.07407407Hyper-methylated PCa|NT DMRs chr11 72954276 72955231 8.96E−05−34.32420635 Hypo-methylated PCa|NT DMRs chr11 72980867 729860220.005896218 20.13508772 Hyper-methylated PCa|NT DMRs chr11 7337251973372610 0.00025637  25.3281746 Hyper-methylated PCa|NT DMRs chr1173668519 73668840 0.000196301 22.63015873 Hyper-methylated PCa|NT DMRschr11 74178026 74179320 5.03E−08 26.42772109 Hyper-methylated PCa|NTDMRs chr11 75139269 75140869 4.23E−09 23.75014006 Hyper-methylatedPCa|NT DMRs chr11 75184864 75188249 0.005574525 −40.15930736Hypo-methylated PCa|NT DMRs chr11 75433466 75433747 0.005968871−50.62857143 Hypo-methylated PCa|NT DMRs chr11 75852175 758524320.007959104 −24.55102041 Hypo-methylated PCa|NT DMRs chr11 7637156576372315 0.00064571  −34.02380952 Hypo-methylated PCa|NT DMRs chr1176375895 76377681 0.000233379 40.86849817 Hyper-methylated PCa|NT DMRschr11 76397539 76397753 0.00064571  53.91836735 Hyper-methylated PCa|NTDMRs chr11 76430376 76430585 6.69E−05 −22.68571429 Hypo-methylatedPCa|NT DMRs chr11 76858730 76859141 3.16E−06 38.00634921Hyper-methylated PCa|NT DMRs chr11 77907224 77907379 2.74E−0521.99548872 Hyper-methylated PCa|NT DMRs chr11 78614210 786145339.87E−08 28.75555556 Hyper-methylated PCa|NT DMRs chr11 8281529382815506 0.004057568 −41.81746032 Hypo-methylated PCa|NT DMRs chr1185521574 85521781 0.009924186 23.12698413 Hyper-methylated PCa|NT DMRschr11 85913749 85913798 0.005968871 39.65714286 Hyper-methylated PCa|NTDMRs chr11 86026752 86087804 0.006882266 21.85513784 Hyper-methylatedPCa|NT DMRs chr11 87100459 87845275 1.02E−07 −36.34900794Hypo-methylated PCa|NT DMRs chr11 87908783 87908950 5.19E−07 20.76190476Hyper-methylated PCa|NT DMRs chr11 88149982 88235508 0.00064571 −21.33386243 Hypo-methylated PCa|NT DMRs chr11 88713712 891355666.76E−07 −28.23308271 Hypo-methylated PCa|NT DMRs chr11 8922450689225015 1.92E−05 23.48370927 Hyper-methylated PCa|NT DMRs chr1189983223 90716615 3.06E−16 −27.08809524 Hypo-methylated PCa|NT DMRschr11 90800075 91145307 4.38E−05 −26.22202381 Hypo-methylated PCa|NTDMRs chr11 91549570 91805803 2.65E−09 −34.98285714 Hypo-methylatedPCa|NT DMRs chr11 91902869 91946834 0.000333533 −29.63027211Hypo-methylated PCa|NT DMRs chr11 93680657 93707470 0.000294557−24.71688312 Hypo-methylated PCa|NT DMRs chr11 93964904 941291085.78E−09 −25.65733333 Hypo-methylated PCa|NT DMRs chr11 9431940494333770 0.003809353 −27.33190476 Hypo-methylated PCa|NT DMRs chr1194840950 94841211 1.42E−05 −31.26530612 Hypo-methylated PCa|NT DMRschr11 96074857 96075066 2.24E−06 23.85854342 Hyper-methylated PCa|NTDMRs chr11 96792815 97538401 6.95E−19 −30.89047619 Hypo-methylatedPCa|NT DMRs chr11 97663020 97695853 0.005968871 −30.34285714Hypo-methylated PCa|NT DMRs chr11 98078394 98294685 5.19E−17−30.17584416 Hypo-methylated PCa|NT DMRs chr11 98341630 986854331.64E−20 −28.06955064 Hypo-methylated PCa|NT DMRs chr11 9901310699279937 2.42E−08 −34.26845238 Hypo-methylated PCa|NT DMRs chr11100146971 100207638 0.001969641 −29.86111111 Hypo-methylated PCa|NT DMRschr11 100359495 100387851 0.000377317 −33.97380952 Hypo-methylatedPCa|NT DMRs chr11 100940788 100941020 0.000118733 −24.65079365Hypo-methylated PCa|NT DMRs chr11 101112312 101437496 8.48E−07−22.31493506 Hypo-methylated PCa|NT DMRs chr11 101558336 1016734960.005968871 −33.05714286 Hypo-methylated PCa|NT DMRs chr11 103497084104031760 2.12E−17 −35.38873626 Hypo-methylated PCa|NT DMRs chr11105716330 105735453 0.000370938 −28.98268398 Hypo-methylated PCa|NT DMRschr11 108389463 108390791 0.007959104 −24.7952381 Hypo-methylated PCa|NTDMRs chr11 108873635 109279296 4.36E−12 −40.08857143 Hypo-methylatedPCa|NT DMRs chr11 109396626 109496463 8.34E−06 −38.78285714Hypo-methylated PCa|NT DMRs chr11 109507475 109931607 4.80E−10−35.96978654 Hypo-methylated PCa|NT DMRs chr11 111154952 1111551211.69E−06 27.54061625 Hyper-methylated PCa|NT DMRs chr11 111228370111250224 4.39E−07 36.79873016 Hyper-methylated PCa|NT DMRs chr11112617155 112705405 0.000163639 −22.57806122 Hypo-methylated PCa|NT DMRschr11 113107412 113108244 0.005968871 −20.66285714 Hypo-methylatedPCa|NT DMRs chill 113846762 113847036 0.005531225 31.61269841Hyper-methylated PCa|NT DMRs chr11 113907106 113911682 0.001965153−22.64835165 Hypo-methylated PCa|NT DMRs chr11 114481872 1144839683.64E−09 −27.20252101 Hypo-methylated PCa|NT DMRs chr11 114760625114835973 0.000787744 −26.25634921 Hypo-methylated PCa|NT DMRs chr11114920485 114920802 0.00064571  −27.61904762 Hypo-methylated PCa|NT DMRschr11 116399323 116438364 0.006257887 −21.85693582 Hypo-methylatedPCa|NT DMRs chr11 116474707 116498296 3.36E−06 −23.76190476Hypo-methylated PCa|NT DMRs chr11 117373488 117373667 0.00641359 −32.36507937 Hypo-methylated PCa|NT DMRs chr11 117459220 1174625711.05E−06 −26.89880952 Hypo-methylated PCa|NT DMRs chr11 117475269117495957 0.005513661 −33.97278912 Hypo-methylated PCa|NT DMRs chr11117534685 117534947 0.007560755 24.57142857 Hyper-methylated PCa|NT DMRschr11 117588832 117589012 0.000974795 −51.65357143 Hypo-methylatedPCa|NT DMRs chr11 117652762 117665030 5.99E−05 −20.62637363Hypo-methylated PCa|NT DMRs chr11 117694283 117699419 2.19E−0831.86058201 Hyper-methylated PCa|NT DMRs chr11 118003671 1180037330.001969641 −37.04761905 Hypo-methylated PCa|NT DMRs chr11 118051171118052222 0.000118733 40.18624339 Hyper-methylated PCa|NT DMRs chr11118505570 118506210 0.002842594 −25.41980952 Hypo-methylated PCa|NT DMRschr11 118743125 118750827 1.42E−05 22.5978836 Hyper-methylated PCa|NTDMRs chr11 118788503 118794718 0.000313712 −20.85102041 Hypo-methylatedPCa|NT DMRs chr11 118986793 118987127 0.002087251 32.71428571Hyper-methylated PCa|NT DMRs chr11 119188026 119188299 0.00339191422.41269841 Hyper-methylated PCa|NT DMRs chr11 119206378 1192066670.004236974 −28.05904762 Hypo-methylated PCa|NT DMRs chr11 119211611119214288 0.005513661 30.14642857 Hyper-methylated PCa|NT DMRs chr11119251680 119252044 0.00023371  28.02597403 Hyper-methylated PCa|NT DMRschr11 119580056 119580589 0.002994094 35.59307359 Hyper-methylatedPCa|NT DMRs chr11 119600926 119618861 7.69E−05 21.91456583Hyper-methylated PCa|NT DMRs chr11 120063694 120074851 0.002647964−29.88435374 Hypo-methylated PCa|NT DMRs chr11 120082136 1200829531.46E−05 21.53030303 Hyper-methylated PCa|NT DMRs chr11 120093121120096386 6.81E−05 35.98571429 Hyper-methylated PCa|NT DMRs chr11120384475 120387576 0.000241095 22.97994987 Hyper-methylated PCa|NT DMRschr11 120387686 120388052 2.05E−05 −30.1462585 Hypo-methylated PCa|NTDMRs chr11 120434823 120435293 8.63E−08 21.55299539 Hyper-methylatedPCa|NT DMRs chr11 120837830 120837916 0.005968871 −44.57142857Hypo-methylated PCa|NT DMRs chr11 121107588 121107707 0.003871035−23.33928571 Hypo-methylated PCa|NT DMRs chr11 121349767 1213499470.005968871 38.02857143 Hyper-methylated PCa|NT DMRs chr11 121533331121565075 4.57E−08 −36.64494048 Hypo-methylated PCa|NT DMRs chr11122873060 122900389 5.05E−06 −21.92142857 Hypo-methylated PCa|NT DMRschr11 122972110 123016468 6.42E−05 −23.76666667 Hypo-methylated PCa|NTDMRs chr11 123461633 123507562 6.90E−06 −32.29904762 Hypo-methylatedPCa|NT DMRs chr11 123651223 123928401 1.55E−06 −34.8375 Hypo-methylatedPCa|NT DMRs chr11 124284677 124311424 0.001969641 −24.05380952Hypo-methylated PCa|NT DMRs chr11 124405040 124435266 0.00064571 −31.62433862 Hypo-methylated PCa|NT DMRs chr11 124628054 1246316673.75E−06 25.27165899 Hyper-methylated PCa|NT DMRs chr11 124715092124716382 0.00641359  23.82380952 Hyper-methylated PCa|NT DMRs chr11124747040 124748116 0.002111644 29.05091575 Hyper-methylated PCa|NT DMRschr11 125743714 125753502 0.001969641 −20.95238095 Hypo-methylatedPCa|NT DMRs chr11 125774146 125774493 4.48E−08 22.19847619Hyper-methylated PCa|NT DMRs chr11 125822831 125823311 0.004095673−48.07936508 Hypo-methylated PCa|NT DMRs chr11 125985045 1259863710.000914361 −37.37585034 Hypo-methylated PCa|NT DMRs chr11 126206659126215206 0.007165874 20.03119048 Hyper-methylated PCa|NT DMRs chr11126316743 126317382 7.18E−06 −20.41111111 Hypo-methylated PCa|NT DMRschr11 126345215 126345532 0.000196301 36.01388889 Hyper-methylatedPCa|NT DMRs chr11 126381434 126390974 2.36E−07 −28.14729064Hypo-methylated PCa|NT DMRs chr11 126455286 126485817 4.34E−07−33.08095238 Hypo-methylated PCa|NT DMRs chr11 126881639 1269871700.000270512 −25.78403361 Hypo-methylated PCa|NT DMRs chr11 127012786127239512 5.68E−12 −29.69825784 Hypo-methylated PCa|NT DMRs chr11127282817 127549907 4.85E−06 −31.00702948 Hypo-methylated PCa|NT DMRschr11 127624031 128103561 3.06E−16 −27.0217484 Hypo-methylated PCa|NTDMRs chr11 128205794 128206332 0.000215808 −21.7037037 Hypo-methylatedPCa|NT DMRs chr11 128685176 128693881 3.82E−05 −25.09747899Hypo-methylated PCa|NT DMRs chr11 128734754 128751765 0.002437742−37.14497354 Hypo-methylated PCa|NT DMRs chr11 130185670 1301857850.001969641 54.56349206 Hyper-methylated PCa|NT DMRs chr11 130271080130271852 0.003622801 43.16666667 Hyper-methylated PCa|NT DMRs chr11131455241 131455478 0.003290817 32.25 Hyper-methylated PCa|NT DMRs chr11132204883 132252514 1.37E−09 −31.74091711 Hypo-methylated PCa|NT DMRschr11 132315341 132558998 1.63E−11 −30.63465608 Hypo-methylated PCa|NTDMRs chr11 132830113 132932992 0.000314331 −22.45813492 Hypo-methylatedPCa|NT DMRs chr11 132945383 132950104 5.87E−05 −28.7110119Hypo-methylated PCa|NT DMRs chr11 133023166 133032523 4.41E−05−21.63151927 Hypo-methylated PCa|NT DMRs chr11 133155303 1332095290.002437742 −28.46031746 Hypo-methylated PCa|NT DMRs chr11 133252438133256936 0.009106413 −36.07380952 Hypo-methylated PCa|NT DMRs chr11133308628 133386584 8.31E−07 −30.09724311 Hypo-methylated PCa|NT DMRschr11 133433718 133653323 5.49E−14 −30.56162047 Hypo-methylated PCa|NTDMRs chr11 133682204 133701882 0.001336455 −30.33928571 Hypo-methylatedPCa|NT DMRs chr11 133788094 133789240 1.87E−06 26.14646465Hyper-methylated PCa|NT DMRs chr11 133789404 133789898 1.14E−0721.66522367 Hyper-methylated PCa|NT DMRs chr11 133798159 1337983300.004350823 −27.63214286 Hypo-methylated PCa|NT DMRs chr11 133821373133821967 2.12E−05 −24.6468254 Hypo-methylated PCa|NT DMRs chr11133841580 133848082 4.09E−06 −27.1115942 Hypo-methylated PCa|NT DMRschr11 133906819 133907005 0.000214406 32.23076923 Hyper-methylatedPCa|NT DMRs chr11 133912462 133914968 0.000118733 −25.57142857Hypo-methylated PCa|NT DMRs chr11 133917160 133920309 4.62E−05−38.92380952 Hypo-methylated PCa|NT DMRs chr11 133939628 1339947630.001764697 −22.58894009 Hypo-methylated PCa|NT DMRs chr11 134009230134011323 0.006589535 −38.02904762 Hypo-methylated PCa|NT DMRs chr11134405717 134406735 0.000269433 40.62755102 Hyper-methylated PCa|NT DMRschr11 134526897 134527288 6.50E−07 −27.13142857 Hypo-methylated PCa|NTDMRs chr11 134670498 134717506 1.74E−06 −21.53794643 Hypo-methylatedPCa|NT DMRs chr11 134854446 134919563 1.05E−07 −21.75687831Hypo-methylated PCa|NT DMRs chr12 569808 570443 7.05E−12 25.60952381Hyper-methylated PCa|NT DMRs chr12 655964 662051 0.002400984−27.98095238 Hypo-methylated PCa|NT DMRs chr12 671272 671670 0.00023371 44.31714286 Hyper-methylated PCa|NT DMRs chr12 679463 681562 0.005669451−35.80532213 Hypo-methylated PCa|NT DMRs chr12 752244 753200 3.19E−0622.85281385 Hyper-methylated PCa|NT DMRs chr12 1025178 1025633 4.54E−0635.5877193 Hyper-methylated PCa|NT DMRs chr12 1582667 15828730.001969641 21.19444444 Hyper-methylated PCa|NT DMRs chr12 16054301605951 0.001969641 −50.22460317 Hypo-methylated PCa|NT DMRs chr121638997 1639209 2.24E−05 20.96357143 Hyper-methylated PCa|NT DMRs chr121640961 1646739 0.000632596 30.02424242 Hyper-methylated PCa|NT DMRschr12 1740149 1740637 1.52E−07 47.83163265 Hyper-methylated PCa|NT DMRschr12 1744770 1744965 0.005968871 48.71428571 Hyper-methylated PCa|NTDMRs chr12 1756030 1756261 0.003290817 39.08035714 Hyper-methylatedPCa|NT DMRs chr12 1770630 1770881 0.000879355 22.00300752Hyper-methylated PCa|NT DMRs chr12 1906018 1907220 3.17E−06 23.7182684Hyper-methylated PCa|NT DMRs chr12 1952172 1954957 0.000145094−24.1765873 Hypo-methylated PCa|NT DMRs chr12 2026839 2027354 1.52E−0744.78231293 Hyper-methylated PCa|NT DMRs chr12 2030167 2030504 5.84E−0549.95436508 Hyper-methylated PCa|NT DMRs chr12 2322888 23230910.001969641 38.07142857 Hyper-methylated PCa|NT DMRs chr12 23392902339614 5.25E−10 26.10770975 Hyper-methylated PCa|NT DMRs chr12 26128632613222 0.008529021 27.36904762 Hyper-methylated PCa|NT DMRs chr123053221 3054641 0.004505524 −25.1265873 Hypo-methylated PCa|NT DMRschr12 3070096 3073324 0.000688325 23.14725275 Hyper-methylated PCa|NTDMRs chr12 3947938 3948441 7.10E−13 42.14937343 Hyper-methylated PCa|NTDMRs chr12 4518923 4535585 0.000715461 −28.33849206 Hypo-methylatedPCa|NT DMRs chr12 4828343 4899022 0.000451335 −25.08955453Hypo-methylated PCa|NT DMRs chr12 4919618 4920724 3.37E−08 −27.98796296Hypo-methylated PCa|NT DMRs chr12 4945911 5003325 3.70E−07 −29.63571429Hypo-methylated PCa|NT DMRs chr12 5155093 5156934 7.44E−06 −46.98241758Hypo-methylated PCa|NT DMRs chr12 5404354 5414842 0.005968871−27.49142857 Hypo-methylated PCa|NT DMRs chr12 5542167 5542931 1.21E−1121.76585366 Hyper-methylated PCa|NT DMRs chr12 5576109 55762720.001241245 −29.03439153 Hypo-methylated PCa|NT DMRs chr12 59971355997258 0.000974795 37.76785714 Hyper-methylated PCa|NT DMRs chr126178534 6184558 1.13E−05 44.17687075 Hyper-methylated PCa|NT DMRs chr126199418 6214697 0.005968871 23.64814815 Hyper-methylated PCa|NT DMRschr12 6319365 6337370 2.32E−05 −29.81162465 Hypo-methylated PCa|NT DMRschr12 6341734 6341821 0.00064571  35.7755102 Hyper-methylated PCa|NTDMRs chr12 6484016 6485475 0.001139334 −36.74563492 Hypo-methylatedPCa|NT DMRs chr12 6493402 6494457 0.008792234 −30.35714286Hypo-methylated PCa|NT DMRs chr12 6641241 6641856 0.00179283  30.6961039Hyper-methylated PCa|NT DMRs chr12 6803209 6804725 0.001175696−26.48823529 Hypo-methylated PCa|NT DMRs chr12 6876688 68800220.000174611 −23.27192118 Hypo-methylated PCa|NT DMRs chr12 68986476901984 0.000652677 37.70912698 Hyper-methylated PCa|NT DMRs chr126933745 6936153 8.74E−07 −29.15619048 Hypo-methylated PCa|NT DMRs chr127044298 7046620 9.50E−05 20.95604396 Hyper-methylated PCa|NT DMRs chr127059950 7066499 7.82E−06 41.83139881 Hyper-methylated PCa|NT DMRs chr127066939 7069094 0.00240833  26.86589862 Hyper-methylated PCa|NT DMRschr12 7071796 7079106 2.50E−08 −35.94417077 Hypo-methylated PCa|NT DMRschr12 7873132 7892159 0.000570576 −25.74338624 Hypo-methylated PCa|NTDMRs chr12 8148528 8170758 0.00017871  −29.46333333 Hypo-methylatedPCa|NT DMRs chr12 8171468 8171769 4.11E−07 21.85714286 Hyper-methylatedPCa|NT DMRs chr12 8320598 8322550 0.00064571  −28.93877551Hypo-methylated PCa|NT DMRs chr12 8413831 8490760 6.78E−07 −26.77595238Hypo-methylated PCa|NT DMRs chr12 8556792 8839279 1.11E−19 −27.72018349Hypo-methylated PCa|NT DMRs chr12 9603044 9603251 6.42E−05 21.82275132Hyper-methylated PCa|NT DMRs chr12 9892632 9901742 0.00179283 −39.88988095 Hypo-methylated PCa|NT DMRs chr12 9966938 100289220.002437742 −34.07671958 Hypo-methylated PCa|NT DMRs chr12 1002903710182598 1.09E−07 −26.39189463 Hypo-methylated PCa|NT DMRs chr1210185237 10253227 6.67E−10 −31.73061224 Hypo-methylated PCa|NT DMRschr12 10291998 10299495 0.000364072 −21.69413919 Hypo-methylated PCa|NTDMRs chr12 10317786 10330979 0.00064571  −30.89387755 Hypo-methylatedPCa|NT DMRs chr12 11700234 11709909 4.80E−06 −38.16051587Hypo-methylated PCa|NT DMRs chr12 11809631 11944107 0.00063518829.64696223 Hyper-methylated PCa|NT DMRs chr12 13080235 130807141.97E−05 −35.70095238 Hypo-methylated PCa|NT DMRs chr12 1342696113505997 0.001181579 −21.85059524 Hypo-methylated PCa|NT DMRs chr1214720581 14721015 3.00E−08 24.51751701 Hyper-methylated PCa|NT DMRschr12 15484014 15626344 1.41E−11 −33.94375804 Hypo-methylated PCa|NTDMRs chr12 16883705 17164660 5.68E−08 −26.17206349 Hypo-methylatedPCa|NT DMRs chr12 17497525 17569867 1.42E−05 −33.63673469Hypo-methylated PCa|NT DMRs chr12 17584274 18526644 2.85E−32 −33.9105723Hypo-methylated PCa|NT DMRs chr12 18857556 19062463 4.02E−05−23.40687831 Hypo-methylated PCa|NT DMRs chr12 21780466 218013270.000205174 −26.83928571 Hypo-methylated PCa|NT DMRs chr12 2197675522049398 1.97E−05 −28.25142857 Hypo-methylated PCa|NT DMRs chr1222486861 22487569 2.17E−07 37.73076923 Hyper-methylated PCa|NT DMRschr12 23406213 23713145 2.32E−06 −27.8789916 Hypo-methylated PCa|NT DMRschr12 23883855 23977802 6.42E−05 −23.51957672 Hypo-methylated PCa|NTDMRs chr12 25079205 25087001 5.33E−05 −22.16190476 Hypo-methylatedPCa|NT DMRs chr12 26427859 26430998 0.000145094 37.40992063Hyper-methylated PCa|NT DMRs chr12 27862851 27863044 0.000847246−26.75457875 Hypo-methylated PCa|NT DMRs chr12 28123939 281286185.06E−15 26.14457455 Hyper-methylated PCa|NT DMRs chr12 3067208730672306 0.001969641 −20.63492063 Hypo-methylated PCa|NT DMRs chr1232163366 32163399 0.001969641 −53.08333333 Hypo-methylated PCa|NT DMRschr12 32330133 32334246 0.001111028 −23.2989418 Hypo-methylated PCa|NTDMRs chr12 34477568 34483952 3.53E−08 −28.12594417 Hypo-methylatedPCa|NT DMRs chr12 34488423 34488683 8.32E−06 −25.76642857Hypo-methylated PCa|NT DMRs chr12 34488817 34489037 0.000746346−23.45904762 Hypo-methylated PCa|NT DMRs chr12 34489145 344893970.000325529 −24.82857143 Hypo-methylated PCa|NT DMRs chr12 3448951834489774 1.48E−05 −28.27329193 Hypo-methylated PCa|NT DMRs chr1234489878 34490201 2.61E−07 −36.86539683 Hypo-methylated PCa|NT DMRschr12 34490425 34491459 1.56E−13 −35.07952381 Hypo-methylated PCa|NTDMRs chr12 34492707 34492747 0.00641359  −23.70238095 Hypo-methylatedPCa|NT DMRs chr12 34492830 34492939 0.00179283  −30.29264069Hypo-methylated PCa|NT DMRs chr12 34494176 34494955 3.24E−10 −33.2031746Hypo-methylated PCa|NT DMRs chr12 34495257 34495730 0.000200681−22.77454844 Hypo-methylated PCa|NT DMRs chr12 34497838 344980330.002097193 −33.34693878 Hypo-methylated PCa|NT DMRs chr12 3449850134499074 3.45E−07 −20.97009967 Hypo-methylated PCa|NT DMRs chrl234499417 34500449 2.02E−13 −33.60384615 Hypo-methylated PCa|NT DMRschr12 34500923 34501516 2.82E−07 −37.93849206 Hypo-methylated PCa|NTDMRs chr12 34502636 34503112 7.57E−05 −36.90952381 Hypo-methylatedPCa|NT DMRs chr12 38551678 38553739 2.97E−20 −24.76375 Hypo-methylatedPCa|NT DMRs chr12 40628426 41040444 7.55E−12 −32.6170068 Hypo-methylatedPCa|NT DMRs chr12 41087584 41160083 0.005968871 −28.95904762Hypo-methylated PCa|NT DMRs chr12 41212912 41272044 0.00064571 −35.93197279 Hypo-methylated PCa|NT DMRs chr12 41966930 422751531.18E−08 −28.08769841 Hypo-methylated PCa|NT DMRs chr12 4378176443908340 1.18E−08 −37.65 Hypo-methylated PCa|NT DMRs chr12 4398879844128510 1.25E−06 −27.42057143 Hypo-methylated PCa|NT DMRs chr1245443339 45444530 8.44E−09 21.16634921 Hyper-methylated PCa|NT DMRschr12 46663445 46663695 4.62E−05 43.91555556 Hyper-methylated PCa|NTDMRs chr12 46767122 46767329 3.44E−06 36.70654762 Hyper-methylatedPCa|NT DMRs chr12 47224672 47225065 1.72E−05 27.76870748Hyper-methylated PCa|NT DMRs chr12 47937757 47952036 0.000377317−25.19795918 Hypo-methylated PCa|NT DMRs chr12 48275613 482771530.005968871 34.23809524 Hyper-methylated PCa|NT DMRs chr12 4859969548665827 0.00064571  −23.28571429 Hypo-methylated PCa|NT DMRs chr1249297470 49298352 0.004543362 28.43223443 Hyper-methylated PCa|NT DMRschr12 49363774 49364578 1.55E−06 21.02364532 Hyper-methylated PCa|NTDMRs chr12 49626915 49627711 0.000118733 39.11904762 Hyper-methylatedPCa|NT DMRs chr12 49688942 49689474 1.57E−07 30.52248677Hyper-methylated PCa|NT DMRs chr12 49726478 49730313 1.07E−0831.48921283 Hyper-methylated PCa|NT DMRs chr12 49731598 497362881.67E−07 21.88538588 Hyper-methylated PCa|NT DMRs chr12 4978024449783223 0.005513661 32.13571429 Hyper-methylated PCa|NT DMRs chr1249943396 49943435 0.005968871 −29.48571429 Hypo-methylated PCa|NT DMRschr12 50099883 50100668 0.000187876 35.15079365 Hyper-methylated PCa|NTDMRs chr12 50297363 50297988 2.63E−09 29.6899696 Hyper-methylated PCa|NTDMRs chr12 50367487 50376049 0.00046742  −48.94545455 Hypo-methylatedPCa|NT DMRs chr12 50432893 50435658 0.005513661 −24.70068027Hypo-methylated PCa|NT DMRs chr12 50497810 50498024 0.000481535−44.74603175 Hypo-methylated PCa|NT DMRs chr12 50506785 505071800.005513661 −40.0922619 Hypo-methylated PCa|NT DMRs chr12 5091216850914115 0.003391914 34.55555556 Hyper-methylated PCa|NT DMRs chr1251712324 51718251 7.44E−10 56.93809524 Hyper-methylated PCa|NT DMRschr12 51729468 51739881 0.001115302 20.70654762 Hyper-methylated PCa|NTDMRs chr12 51785969 51788039 2.64E−08 29.53261183 Hyper-methylatedPCa|NT DMRs chr12 52317218 52317733 0.002034353 21.16326531Hyper-methylated PCa|NT DMRs chr12 52400495 52401828 3.27E−3229.62617013 Hyper-methylated PCa|NT DMRs chr12 52509677 525119850.00064571  −44.88503401 Hypo-methylated PCa|NT DMRs chr12 5271500652715044 0.001969641 −24.33333333 Hypo-methylated PCa|NT DMRs chr1253128380 53130503 0.005968871 −32.09714286 Hypo-methylated PCa|NT DMRschr12 53207442 53212769 0.001426157 −23.10084034 Hypo-methylated PCa|NTDMRs chr12 53268065 53268290 3.05E−09 25.05494505 Hyper-methylatedPCa|NT DMRs chr12 53298237 53298969 0.001111028 −39.9047619Hypo-methylated PCa|NT DMRs chr12 53359203 53359419 0.00048038331.14285714 Hyper-methylated PCa|NT DMRs chr12 53441697 534468770.000516057 −33.92307692 Hypo-methylated PCa|NT DMRs chr12 5361723953617383 2.86E−05 29.03296703 Hyper-methylated PCa|NT DMRs chr1253836400 53836517 0.005968871 34.38761905 Hyper-methylated PCa|NT DMRschr12 54131102 54135269 0.004227093 25.69708995 Hyper-methylated PCa|NTDMRs chr12 54321497 54330957 3.33E−10 21.83178054 Hyper-methylatedPCa|NT DMRs chr12 54376047 54380101 4.09E−15 27.38863287Hyper-methylated PCa|NT DMRs chr12 54407959 54409526 9.69E−1240.35896359 Hyper-methylated PCa|NT DMRs chr12 54428362 544543752.16E−33 39.01127232 Hyper-methylated PCa|NT DMRs chr12 5447426554475553 0.005968871 33.82857143 Hyper-methylated PCa|NT DMRs chr1254500141 54500787 3.60E−10 32.46699507 Hyper-methylated PCa|NT DMRschr12 54719728 54719764 0.001969641 −39.5952381 Hypo-methylated PCa|NTDMRs chr12 54755304 54756713 0.004236974 −20.72571429 Hypo-methylatedPCa|NT DMRs chr12 54806218 54812532 0.000238731 33.46078431Hyper-methylated PCa|NT DMRs chr12 56115070 56120638 0.004071561−25.31587302 Hypo-methylated PCa|NT DMRs chr12 57094398 570946460.000481535 53.51851852 Hyper-methylated PCa|NT DMRs chr12 5754577557546086 0.001969641 −28.8468254 Hypo-methylated PCa|NT DMRs chr1257550599 57550897 4.28E−07 41.99428571 Hyper-methylated PCa|NT DMRschr12 57634856 57635744 4.42E−05 25.47985348 Hyper-methylated PCa|NTDMRs chr12 57958739 57963109 0.005968871 −25.18666667 Hypo-methylatedPCa|NT DMRs chr12 58119674 58122083 7.14E−09 −46.36507937Hypo-methylated PCa|NT DMRs chr12 59395863 59981266 4.85E−16−31.45753158 Hypo-methylated PCa|NT DMRs chr12 60008487 602253354.11E−07 −32.64987469 Hypo-methylated PCa|NT DMRs chr12 6061947760642817 0.00064571  −33.83401361 Hypo-methylated PCa|NT DMRs chr1260782219 61788649 2.04E−17 −21.89330573 Hypo-methylated PCa|NT DMRschr12 62266135 62510885 1.91E−07 −21.53358396 Hypo-methylated PCa|NTDMRs chr12 65218335 65220299 2.27E−27 38.01987818 Hyper-methylatedPCa|NT DMRs chr12 65515438 65515703 3.77E−05 34.02946429Hyper-methylated PCa|NT DMRs chr12 65672082 65672234 0.00083613224.46190476 Hyper-methylated PCa|NT DMRs chr12 65801968 659974610.000133155 −31.87103175 Hypo-methylated PCa|NT DMRs chr12 6627557066276260 1.02E−09 32.65873016 Hyper-methylated PCa|NT DMRs chr1268757487 68759201 0.000949805 33.87103175 Hyper-methylated PCa|NT DMRschr12 68825940 68848995 0.00641359  −41.41587302 Hypo-methylated PCa|NTDMRs chr12 72079236 72079323 0.00064571  −48.46938776 Hypo-methylatedPCa|NT DMRs chr12 72395098 72645075 1.32E−08 −28.28265306Hypo-methylated PCa|NT DMRs chr12 74635771 74665046 8.05E−06−21.05619048 Hypo-methylated PCa|NT DMRs chr12 75960802 761177806.42E−05 −23.58095238 Hypo-methylated PCa|NT DMRs chr12 8224624782286973 0.001969641 −32 Hypo-methylated PCa|NT DMRs chr12 8427421184433624 0.001241245 −29.14867725 Hypo-methylated PCa|NT DMRs chr1284518549 84549192 3.05E−06 −30.50769231 Hypo-methylated PCa|NT DMRschr12 85187989 85229497 1.42E−05 −40.23979592 Hypo-methylated PCa|NTDMRs chr12 85896678 86215567 1.26E−05 −31.45291005 Hypo-methylatedPCa|NT DMRs chr12 86407124 86434887 1.03E−05 −30.42857143Hypo-methylated PCa|NT DMRs chr12 87781481 88226255 1.41E−07−24.08712522 Hypo-methylated PCa|NT DMRs chr12 89744877 897451930.00016423  23.41501832 Hyper-methylated PCa|NT DMRs chr12 9454385094568501 4.42E−08 20.6626294 Hyper-methylated PCa|NT DMRs chr12 9462616094658281 0.006025732 −34.86428571 Hypo-methylated PCa|NT DMRs chr1295038193 95039405 0.005513661 42.05357143 Hyper-methylated PCa|NT DMRschr12 95840421 95840829 0.000165902 40.11941392 Hyper-methylated PCa|NTDMRs chr12 96183288 96183883 1.05E−10 27.01123321 Hyper-methylatedPCa|NT DMRs chr12 96388463 96395696 0.000123553 20.89635854Hyper-methylated PCa|NT DMRs chr12 98767469 98781960 0.00641359  −40Hypo-methylated PCa|NT DMRs chr12 100774654 100779268 0.002585277−27.48809524 Hypo-methylated PCa|NT DMRs chr12 103498427 1034985110.005968871 −38.03333333 Hypo-methylated PCa|NT DMRs chr12 103695950103696238 1.52E−07 27.57891156 Hyper-methylated PCa|NT DMRs chr12104697450 104697846 1.61E−10 29.16885457 Hyper-methylated PCa|NT DMRschr12 104851871 104853159 9.54E−13 32.41496599 Hyper-methylated PCa|NTDMRs chr12 105107480 105109310 0.005968871 −33.4 Hypo-methylated PCa|NTDMRs chr12 105477686 105477733 0.00641359  23.33333333 Hyper-methylatedPCa|NT DMRs chr12 106022076 106022112 0.005968871 −30.84 Hypo-methylatedPCa|NT DMRs chr12 106531772 106532142 0.000111427 29.58285714Hyper-methylated PCa|NT DMRs chr12 106533464 106533737 8.47E−0629.96969697 Hyper-methylated PCa|NT DMRs chr12 107039031 1070390980.001969641 −51.04761905 Hypo-methylated PCa|NT DMRs chr12 107297126107297326 0.002437742 24.28835979 Hyper-methylated PCa|NT DMRs chr12108347105 108399657 0.001969641 −37.0515873 Hypo-methylated PCa|NT DMRschr12 109162275 109162678 2.99E−07 28.71530612 Hyper-methylated PCa|NTDMRs chr12 109273780 109278217 0.003871035 −27.56785714 Hypo-methylatedPCa|NT DMRs chr12 109297307 109299060 0.001241245 24.76190476Hyper-methylated PCa|NT DMRs chr12 109526810 109527869 0.006589535−30.18857143 Hypo-methylated PCa|NT DMRs chr12 109711168 1097113320.001969641 33.45238095 Hyper-methylated PCa|NT DMRs chr12 109716837109716969 0.00064571  −45.07142857 Hypo-methylated PCa|NT DMRs chr12109729299 109729961 3.87E−06 30.06893424 Hyper-methylated PCa|NT DMRschr12 110156175 110157510 1.66E−05 36.91456583 Hyper-methylated PCa|NTDMRs chr12 110265801 110266248 6.69E−05 50.88190476 Hyper-methylatedPCa|NT DMRs chr12 111112991 111117302 0.005968871 −32.98 Hypo-methylatedPCa|NT DMRs chr12 111331137 111331381 0.001969641 −40.22619048Hypo-methylated PCa|NT DMRs chr12 111456714 111456855 0.004095673−34.50793651 Hypo-methylated PCa|NT DMRs chr12 111470768 1114708280.001969641 41.39047619 Hyper-methylated PCa|NT DMRs chr12 111593459111596411 0.007305013 22.31547619 Hyper-methylated PCa|NT DMRs chr12111599699 111604656 0.007305013 −46.46785714 Hypo-methylated PCa|NT DMRschr12 111798936 111799226 0.00064571  37.85714286 Hyper-methylatedPCa|NT DMRs chr12 111842687 111842940 6.42E−05 31.69417989Hyper-methylated PCa|NT DMRs chr12 111844152 111847845 3.10E−1236.89194139 Hyper-methylated PCa|NT DMRs chr12 112591144 1125916360.005968871 −27.4 Hypo-methylated PCa|NT DMRs chr12 112835090 1128355260.008482405 −34.77142857 Hypo-methylated PCa|NT DMRs chr12 113031027113229124 4.40E−07 −24.31471861 Hypo-methylated PCa|NT DMRs chr12113234577 113307766 1.15E−08 −29.43756614 Hypo-methylated PCa|NT DMRschr12 113499672 113504056 0.000301781 23.0517316 Hyper-methylated PCa|NTDMRs chr12 113521291 113531394 0.000346222 20.35289575 Hyper-methylatedPCa|NT DMRs chr12 113679215 113684696 0.001216064 −26.65483871Hypo-methylated PCa|NT DMRs chr12 113770527 113771942 0.00620727130.31190476 Hyper-methylated PCa|NT DMRs chr12 114162770 1141630531.97E−05 −53.27809524 Hypo-methylated PCa|NT DMRs chr12 114192081114204098 2.45E−07 −31.16929392 Hypo-methylated PCa|NT DMRs chr12115133106 115152344 4.14E−05 46.20972222 Hyper-methylated PCa|NT DMRschr12 115153881 115174322 6.44E−06 35.96550265 Hyper-methylated PCa|NTDMRs chr12 115573770 115576790 0.007560755 −34.97777778 Hypo-methylatedPCa|NT DMRs chr12 116037353 116062028 3.96E−05 32.35892857Hyper-methylated PCa|NT DMRs chr12 116278193 116278292 0.005968871−46.06857143 Hypo-methylated PCa|NT DMRs chr12 116716409 1167243326.42E−05 41.56402116 Hyper-methylated PCa|NT DMRs chr12 116831310116831525 0.005513661 30.3877551 Hyper-methylated PCa|NT DMRs chr12116922248 116922446 0.001181579 −26.67346939 Hypo-methylated PCa|NT DMRschr12 116946159 116946306 7.70E−09 29.45308642 Hyper-methylated PCa|NTDMRs chr12 116996796 116997121 0.000176046 50.85281385 Hyper-methylatedPCa|NT DMRs chr12 117096354 117096479 0.003622801 −30.96666667Hypo-methylated PCa|NT DMRs chr12 117129243 117133383 2.29E−0628.6505291 Hyper-methylated PCa|NT DMRs chr12 117135779 1171556740.000188172 −28.63756614 Hypo-methylated PCa|NT DMRs chr12 117477883117478603 0.000117699 43.87012987 Hyper-methylated PCa|NT DMRs chr12117482953 117486917 0.000363991 31.76296296 Hyper-methylated PCa|NT DMRschr12 117501297 117501486 0.002437742 46.03809524 Hyper-methylatedPCa|NT DMRs chr12 117580082 117583972 0.000141004 −34.20502646Hypo-methylated PCa|NT DMRs chr12 117658428 117658788 0.001969641−31.45634921 Hypo-methylated PCa|NT DMRs chr12 117771728 1177727690.00641359  −31.93650794 Hypo-methylated PCa|NT DMRs chr12 118569390118569736 0.00064571  −38.18367347 Hypo-methylated PCa|NT DMRs chr12119070924 119206291 0.006225823 −22.72510823 Hypo-methylated PCa|NT DMRschr12 119216863 119407630 0.000567209 −27.97619048 Hypo-methylatedPCa|NT DMRs chr12 119653771 119695299 0.00051204  −25.98761905Hypo-methylated PCa|NT DMRs chr12 120106954 120107676 0.000167524−24.59275362 Hypo-methylated PCa|NT DMRs chr12 120700871 1207011750.000570576 −37.57354497 Hypo-methylated PCa|NT DMRs chr12 120799332120799725 2.39E−08 42.09213251 Hyper-methylated PCa|NT DMRs chr12120877112 120877187 0.001969641 −35.49603175 Hypo-methylated PCa|NT DMRschr12 120973751 120975323 0.003122338 −32.49603175 Hypo-methylatedPCa|NT DMRs chr12 121456139 121456255 0.00179283  28.02380952Hyper-methylated PCa|NT DMRs chr12 121565718 121565847 0.005968871−24.55428571 Hypo-methylated PCa|NT DMRs chr12 121716976 1217287843.96E−08 −37.09365079 Hypo-methylated PCa|NT DMRs chr12 121735816121735963 0.00064571  −42.3877551 Hypo-methylated PCa|NT DMRs chr12121881969 121882219 1.76E−06 −37.26190476 Hypo-methylated PCa|NT DMRschr12 121890460 121890799 0.001391421 24.93896104 Hyper-methylatedPCa|NT DMRs chr12 122014850 122017085 4.42E−12 30.87284226Hyper-methylated PCa|NT DMRs chr12 122018897 122020662 0.00603903 29.97671958 Hyper-methylated PCa|NT DMRs chr12 122233453 1222372902.86E−06 −39.08822055 Hypo-methylated PCa|NT DMRs chr12 122243926122248654 8.34E−08 −23.51671335 Hypo-methylated PCa|NT DMRs chr12122356025 122356144 6.42E−05 −21.89153439 Hypo-methylated PCa|NT DMRschr12 122444219 122444664 0.000149331 20.66233766 Hyper-methylatedPCa|NT DMRs chr12 122458822 122458917 0.000250214 −25.61904762Hypo-methylated PCa|NT DMRs chr12 122622501 122622628 0.000481535−30.98412698 Hypo-methylated PCa|NT DMRs chr12 122669143 1226694996.69E−05 51.23571429 Hyper-methylated PCa|NT DMRs chr12 123131635123131816 0.001969641 62.47619048 Hyper-methylated PCa|NT DMRs chr12123350609 123350956 0.007679542 26.36507937 Hyper-methylated PCa|NT DMRschr12 123428003 123432025 0.001170059 36.55380952 Hyper-methylatedPCa|NT DMRs chr12 123454719 123458517 0.00064571  −43.71428571Hypo-methylated PCa|NT DMRs chr12 123469208 123469588 3.36E−0632.4622449 Hyper-methylated PCa|NT DMRs chr12 123516088 1235193100.000475166 39.64761905 Hyper-methylated PCa|NT DMRs chr12 123738801123745121 0.000205174 −39.28511905 Hypo-methylated PCa|NT DMRs chr12123877672 123884045 4.90E−06 −46.30505952 Hypo-methylated PCa|NT DMRschr12 124539311 124539401 0.005968871 21.00571429 Hyper-methylatedPCa|NT DMRs chr12 124770923 124774533 0.003764982 −28.99801587Hypo-methylated PCa|NT DMRs chr12 124779455 124779574 0.00858178220.77777778 Hyper-methylated PCa|NT DMRs chr12 124780181 1247812105.12E−11 38.87738095 Hyper-methylated PCa|NT DMRs chr12 124781699124781926 0.00064571  −44.7755102 Hypo-methylated PCa|NT DMRs chr12124841219 124846100 4.03E−05 −29.51661601 Hypo-methylated PCa|NT DMRschr12 124853894 124856388 2.57E−11 −58.2122449 Hypo-methylated PCa|NTDMRs chr12 124864594 124864658 0.005968871 34.57142857 Hyper-methylatedPCa|NT DMRs chr12 124877457 124889142 3.38E−05 −23.55468254Hypo-methylated PCa|NT DMRs chr12 124905648 124908130 0.000229601−39.37946429 Hypo-methylated PCa|NT DMRs chr12 124925728 1249275520.001969641 −24.17063492 Hypo-methylated PCa|NT DMRs chr12 124937758124942464 2.06E−10 44.25765766 Hyper-methylated PCa|NT DMRs chr12124950553 124951223 5.51E−08 51.71861472 Hyper-methylated PCa|NT DMRschr12 124982371 124983008 0.000215808 35.66666667 Hyper-methylatedPCa|NT DMRs chr12 124985381 124986238 0.00064571  29.15306122Hyper-methylated PCa|NT DMRs chr12 124986459 124986722 0.000250214−35.29285714 Hypo-methylated PCa|NT DMRs chr12 125000485 1250034301.41E−13 −21.25889436 Hypo-methylated PCa|NT DMRs chr12 125028943125030659 0.000349416 24.90225564 Hyper-methylated PCa|NT DMRs chr12125076772 125091185 0.000924001 23.57192982 Hyper-methylated PCa|NT DMRschr12 125101264 125101443 0.001969641 38.71428571 Hyper-methylatedPCa|NT DMRs chr12 125258704 125258850 0.000205174 39.92678571Hyper-methylated PCa|NT DMRs chr12 125322777 125322961 0.00064571 −56.99319728 Hypo-methylated PCa|NT DMRs chr12 125341263 1253415070.002534928 32.61857143 Hyper-methylated PCa|NT DMRs chr12 125353643125353743 0.005968871 49.63714286 Hyper-methylated PCa|NT DMRs chr12125413033 125413165 0.000205174 21.5 Hyper-methylated PCa|NT DMRs chr12125670133 125670341 0.000635257 23.37254902 Hyper-methylated PCa|NT DMRschr12 127545339 127630315 0.000207233 −30.74732143 Hypo-methylatedPCa|NT DMRs chr12 127631151 127645653 7.57E−05 −28.73571429Hypo-methylated PCa|NT DMRs chr12 127666101 127751370 0.000974795−37.81547619 Hypo-methylated PCa|NT DMRs chr12 127771410 1278390875.94E−06 −36.995671 Hypo-methylated PCa|NT DMRs chr12 127868235127938771 4.10E−08 −33.52666667 Hypo-methylated PCa|NT DMRs chr12127941049 127962865 3.20E−05 −33.25442177 Hypo-methylated PCa|NT DMRschr12 127967686 128154845 1.17E−15 −33.24277778 Hypo-methylated PCa|NTDMRs chr12 128210131 128235755 0.000179253 −31.6007326 Hypo-methylatedPCa|NT DMRs chr12 128335466 128383456 1.57E−07 −35.27365079Hypo-methylated PCa|NT DMRs chr12 128675569 128750043 0.003520801−30.51071429 Hypo-methylated PCa|NT DMRs chr12 128762836 1288138791.69E−06 −33.41344538 Hypo-methylated PCa|NT DMRs chr12 128852810128865999 1.93E−06 −32.86616541 Hypo-methylated PCa|NT DMRs chr12129458299 129552362 2.35E−12 −29.82289377 Hypo-methylated PCa|NT DMRschr12 129702538 129716266 0.000377317 −27.63809524 Hypo-methylatedPCa|NT DMRs chr12 130300244 130317296 7.64E−07 −23.36825397Hypo-methylated PCa|NT DMRs chr12 130540502 130568557 2.54E−07−24.95044643 Hypo-methylated PCa|NT DMRs chr12 130580399 1305858123.20E−05 −31.65966387 Hypo-methylated PCa|NT DMRs chr12 130590155130603569 9.42E−12 −31.64875776 Hypo-methylated PCa|NT DMRs chr12130612346 130640384 2.30E−17 −31.96168582 Hypo-methylated PCa|NT DMRschr12 130645328 130645375 0.000117507 24.61038961 Hyper-methylatedPCa|NT DMRs chr12 130663490 130670959 2.95E−09 −30.62236652Hypo-methylated PCa|NT DMRs chr12 130680211 130683050 0.000106046−36.92857143 Hypo-methylated PCa|NT DMRs chr12 130699859 1307533747.85E−11 −31.72954823 Hypo-methylated PCa|NT DMRs chr12 130910143130942579 9.00E−32 −27.48298137 Hypo-methylated PCa|NT DMRs chr12131096742 131122403 3.09E−05 −25.62199546 Hypo-methylated PCa|NT DMRschr12 131214254 131237782 6.47E−07 −26.91795918 Hypo-methylated PCa|NTDMRs chr12 131245704 131260185 0.000363991 −24.47759104 Hypo-methylatedPCa|NT DMRs chr12 131260380 131260684 0.000652115 22.76923077Hyper-methylated PCa|NT DMRs chr12 131439121 131462102 9.19E−10−24.33410138 Hypo-methylated PCa|NT DMRs chr12 131474131 1314787921.13E−05 −24.78864469 Hypo-methylated PCa|NT DMRs chr12 131492861131496958 1.68E−07 −29.31071429 Hypo-methylated PCa|NT DMRs chr12131519674 131520766 0.000729802 −35.7984127 Hypo-methylated PCa|NT DMRschr12 131522919 131527770 2.52E−10 −24.7997426 Hypo-methylated PCa|NTDMRs chr12 131588340 131589170 0.000570576 −28.49450549 Hypo-methylatedPCa|NT DMRs chr12 131604065 131607137 1.63E−08 −26.21612903Hypo-methylated PCa|NT DMRs chr12 131653302 131694221 8.73E−16−31.75753968 Hypo-methylated PCa|NT DMRs chr12 131812802 1318638766.89E−19 −29.5207483 Hypo-methylated PCa|NT DMRs chr12 131872360131876009 0.001860863 −24.2327381 Hypo-methylated PCa|NT DMRs chr12131892700 131916572 5.88E−11 −39.03392857 Hypo-methylated PCa|NT DMRschr12 131923698 131933022 1.12E−08 −28.00677656 Hypo-methylated PCa|NTDMRs chr12 131941562 132017866 1.82E−21 −31.67383966 Hypo-methylatedPCa|NT DMRs chr12 132041856 132106912 4.44E−37 −29.70204518Hypo-methylated PCa|NT DMRs chr12 132107115 132122144 4.31E−08−25.94790765 Hypo-methylated PCa|NT DMRs chr12 132336728 1323377294.57E−06 34.46043956 Hyper-methylated PCa|NT DMRs chr12 132340000132340675 0.000916248 −24.93253968 Hypo-methylated PCa|NT DMRs chr12132345320 132345483 0.001181579 33.3877551 Hyper-methylated PCa|NT DMRschr12 132423427 132423733 0.001181579 −47.63265306 Hypo-methylatedPCa|NT DMRs chr12 132663394 132663456 0.000205174 −25.64285714Hypo-methylated PCa|NT DMRs chr12 132666489 132671672 0.00046169627.10140056 Hyper-methylated PCa|NT DMRs chr12 132687778 1326880310.000688325 −27.71794872 Hypo-methylated PCa|NT DMRs chr12 132688909132689836 0.000308889 −32.90050125 Hypo-methylated PCa|NT DMRs chr12132699875 132704243 0.000272699 −25.45468975 Hypo-methylated PCa|NT DMRschr12 132849461 132852604 1.14E−06 −21.44015444 Hypo-methylated PCa|NTDMRs chr12 132856070 132857869 0.000323929 −27.8047619 Hypo-methylatedPCa|NT DMRs chr12 132922058 132924382 1.96E−08 −21.01972789Hypo-methylated PCa|NT DMRs chr12 132934577 132934641 1.97E−05−33.71428571 Hypo-methylated PCa|NT DMRs chr12 132938014 1329401230.001241245 −26.88941799 Hypo-methylated PCa|NT DMRs chr12 132977135132979726 0.004045699 −24.15833333 Hypo-methylated PCa|NT DMRs chr12132980227 132981745 0.000754912 −27.82507937 Hypo-methylated PCa|NT DMRschr12 132991172 132991480 0.002580892 −20.46865079 Hypo-methylatedPCa|NT DMRs chr12 133014314 133014429 0.001969641 31.97619048Hyper-methylated PCa|NT DMRs chr12 133015600 133017219 0.00622582334.50649351 Hyper-methylated PCa|NT DMRs chr12 133021105 1330217610.00026034  41.33374741 Hyper-methylated PCa|NT DMRs chr12 133081803133082783 0.004496757 23.8358396 Hyper-methylated PCa|NT DMRs chr12133083468 133083918 2.42E−05 27.96984127 Hyper-methylated PCa|NT DMRschr12 133134890 133136070 2.29E−06 39.42792208 Hyper-methylated PCa|NTDMRs chr12 133346473 133348453 5.11E−05 43.11339286 Hyper-methylatedPCa|NT DMRs chr12 133350847 133355607 3.74E−06 −22.51949405Hypo-methylated PCa|NT DMRs chr12 133442840 133449282 0.00082238838.05324675 Hyper-methylated PCa|NT DMRs chr12 133458790 1334590890.00064571  −23.48979592 Hypo-methylated PCa|NT DMRs chr12 133481352133481529 1.21E−06 21.42698413 Hyper-methylated PCa|NT DMRs chr1319183558 19183583 0.007959104 25.8 Hyper-methylated PCa|NT DMRs chr1319457406 19518336 1.52E−09 −21.17973422 Hypo-methylated PCa|NT DMRschr13 20023259 20125651 0.000226106 −32.43040293 Hypo-methylated PCa|NTDMRs chr13 20735461 20766327 5.71E−15 28.08456486 Hyper-methylatedPCa|NT DMRs chr13 21519813 21520564 3.06E−05 33.12205514Hyper-methylated PCa|NT DMRs chr13 21649287 21649454 0.00596887154.44285714 Hyper-methylated PCa|NT DMRs chr13 22408162 224942771.80E−14 −30.40739796 Hypo-methylated PCa|NT DMRs chr13 2250274522551968 6.37E−13 −32.81174603 Hypo-methylated PCa|NT DMRs chr1324289374 24289782 0.000205174 −38.58928571 Hypo-methylated PCa|NT DMRschr13 25115530 25115729 0.002770271 23.14285714 Hyper-methylated PCa|NTDMRs chr13 25635592 25643451 4.36E−06 −28.03781513 Hypo-methylatedPCa|NT DMRs chr13 27295824 27296022 5.19E−07 34.13772894Hyper-methylated PCa|NT DMRs chr13 27846149 27847366 0.004677148−34.67272727 Hypo-methylated PCa|NT DMRs chr13 28318676 283187290.001969641 −40.63888889 Hypo-methylated PCa|NT DMRs chr13 2836362528364738 7.87E−12 21.6172619 Hyper-methylated PCa|NT DMRs chr13 2841735028432473 0.000603675 −26.18392857 Hypo-methylated PCa|NT DMRs chr1328527434 28527935 1.49E−06 24.32640693 Hyper-methylated PCa|NT DMRschr13 28541098 28541421 0.000159287 20.22539683 Hyper-methylated PCa|NTDMRs chr13 28944197 29060644 0.003122338 −38.9734127 Hypo-methylatedPCa|NT DMRs chr13 29157973 29220757 0.001902894 −25.97321429Hypo-methylated PCa|NT DMRs chr13 30077315 30077371 0.000974795 35.5Hyper-methylated PCa|NT DMRs chr13 30251580 30268118 0.000972067−24.36785714 Hypo-methylated PCa|NT DMRs chr13 30681749 306819980.00064571  44.32653061 Hyper-methylated PCa|NT DMRs chr13 3143707131437213 0.005968871 −51.11428571 Hypo-methylated PCa|NT DMRs chr1331446658 31470101 0.001254235 −21.43589744 Hypo-methylated PCa|NT DMRschr13 31480865 31481662 1.76E−06 27.36507937 Hyper-methylated PCa|NTDMRs chr13 31573145 31595895 0.00017871  −20.84857143 Hypo-methylatedPCa|NT DMRs chr13 34909982 34910047 0.005968871 −40.63809524Hypo-methylated PCa|NT DMRs chr13 37122118 37125383 0.005968871−25.38666667 Hypo-methylated PCa|NT DMRs chr13 37729815 381596547.66E−12 −25.1231685 Hypo-methylated PCa|NT DMRs chr13 38307851 384025410.003892841 −22.10899471 Hypo-methylated PCa|NT DMRs chr13 3844310438443480 1.92E−05 30.28125 Hyper-methylated PCa|NT DMRs chr13 3970173039805476 0.00068166  −29.63035714 Hypo-methylated PCa|NT DMRs chr1340402446 40410011 0.00641359  −23.6547619 Hypo-methylated PCa|NT DMRschr13 40791366 40850557 0.002437742 −25.01216931 Hypo-methylated PCa|NTDMRs chr13 44947701 44948373 9.40E−25 23.09492888 Hyper-methylatedPCa|NT DMRs chr13 44980998 44995041 0.009510325 22.24732143Hyper-methylated PCa|NT DMRs chr13 45493435 45495087 0.000822388−21.85952381 Hypo-methylated PCa|NT DMRs chr13 45535113 455624120.005968871 −28.1352381 Hypo-methylated PCa|NT DMRs chr13 4670898846736724 0.002770271 −29.23333333 Hypo-methylated PCa|NT DMRs chr1347392321 47447169 0.001480644 −41.76761905 Hypo-methylated PCa|NT DMRschr13 48891926 48895324 3.37E−30 28.2506008 Hyper-methylated PCa|NT DMRschr13 49888148 49888351 0.001969641 −50.27380952 Hypo-methylated PCa|NTDMRs chr13 50070551 50070719 1.97E−05 40.36428571 Hyper-methylatedPCa|NT DMRs chr13 50704030 50704319 0.001429556 24.32987013Hyper-methylated PCa|NT DMRs chr13 50706360 50708019 3.24E−08 32.2772381Hyper-methylated PCa|NT DMRs chr13 50901229 50940003 0.004057568−31.94603175 Hypo-methylated PCa|NT DMRs chr13 51861176 518668250.00064571  −27.05782313 Hypo-methylated PCa|NT DMRs chr13 5276678552767044 0.001969641 −38.30555556 Hypo-methylated PCa|NT DMRs chr1352918039 52918598 0.005968871 −21.38285714 Hypo-methylated PCa|NT DMRschr13 54357656 54396152 1.76E−06 −47.01865079 Hypo-methylated PCa|NTDMRs chr13 55403634 55628877 3.58E−08 −27.47517007 Hypo-methylatedPCa|NT DMRs chr13 56075445 56537800 5.35E−12 −33.41660859Hypo-methylated PCa|NT DMRs chr13 57204589 57476539 3.97E−12−25.51481481 Hypo-methylated PCa|NT DMRs chr13 57545059 577689390.000143553 −28.20714286 Hypo-methylated PCa|NT DMRs chr13 5786055957860886 0.000117699 −31.94805195 Hypo-methylated PCa|NT DMRs chr1358368916 58826515 2.28E−11 −36.03611111 Hypo-methylated PCa|NT DMRschr13 60841835 60842991 0.003892841 23.17460317 Hyper-methylated PCa|NTDMRs chr13 61804141 61804730 6.42E−05 −25.87830688 Hypo-methylatedPCa|NT DMRs chr13 61987935 61988042 6.42E−05 26.06402116Hyper-methylated PCa|NT DMRs chr13 62359010 62499812 1.37E−09−28.52857143 Hypo-methylated PCa|NT DMRs chr13 64167770 644050612.89E−14 −24.96595745 Hypo-methylated PCa|NT DMRs chr13 6442168464603893 6.90E−06 −30.17301587 Hypo-methylated PCa|NT DMRs chr1364652771 64664705 9.62E−06 −26.44444444 Hypo-methylated PCa|NT DMRschr13 66357827 66444160 5.44E−07 −29.2556391 Hypo-methylated PCa|NT DMRschr13 67311776 67311966 0.001789867 −28.55343915 Hypo-methylated PCa|NTDMRs chr13 67568473 67568589 0.000205174 28.22380952 Hyper-methylatedPCa|NT DMRs chr13 67974608 68349966 1.47E−11 −33.18893557Hypo-methylated PCa|NT DMRs chr13 71546030 71724087 0.001969641−31.06394558 Hypo-methylated PCa|NT DMRs chr13 74666532 747082855.00E−07 24.14506803 Hyper-methylated PCa|NT DMRs chr13 7620939576209621 8.73E−05 −31.9744898 Hypo-methylated PCa|NT DMRs chr13 7811706378132808 0.001181579 −39.33333333 Hypo-methylated PCa|NT DMRs chr1379284992 79942284 6.48E−16 −30.59349962 Hypo-methylated PCa|NT DMRschr13 80426582 80823358 4.24E−17 −31.77419913 Hypo-methylated PCa|NTDMRs chr13 80937371 81198124 4.62E−14 −33.21168831 Hypo-methylatedPCa|NT DMRs chr13 81324988 81600596 1.47E−07 −29.12212885Hypo-methylated PCa|NT DMRs chr13 82088183 82308857 2.81E−09−29.90095238 Hypo-methylated PCa|NT DMRs chr13 84480709 846108611.43E−08 −29.08456486 Hypo-methylated PCa|NT DMRs chr13 8505858185058635 0.000974795 −31.66369048 Hypo-methylated PCa|NT DMRs chr1385470198 85536515 2.73E−08 −29.34927536 Hypo-methylated PCa|NT DMRschr13 86427492 86498929 6.56E−06 −29.73730159 Hypo-methylated PCa|NTDMRs chr13 86590986 87420902 4.90E−14 −29.40592992 Hypo-methylatedPCa|NT DMRs chr13 87490771 87542596 0.00051204  −25.11190476Hypo-methylated PCa|NT DMRs chr13 88435008 88600195 9.35E−06−29.79546485 Hypo-methylated PCa|NT DMRs chr13 90026614 903177491.87E−16 −29.87725948 Hypo-methylated PCa|NT DMRs chr13 9374408593748882 0.000172237 −23.98707483 Hypo-methylated PCa|NT DMRs chr1395620295 95719742 5.56E−20 26.89817276 Hyper-methylated PCa|NT DMRschr13 95845546 95855253 0.003305567 −22.65833333 Hypo-methylated PCa|NTDMRs chr13 96294544 96296438 2.16E−06 22.59863946 Hyper-methylatedPCa|NT DMRs chr13 98866102 98866483 0.000554289 −30.99206349Hypo-methylated PCa|NT DMRs chr13 99057348 99058218 0.001969641−37.11904762 Hypo-methylated PCa|NT DMRs chr13 99064004 990641930.008482405 50.71428571 Hyper-methylated PCa|NT DMRs chr13 9908336699083678 6.94E−06 −45.36952381 Hypo-methylated PCa|NT DMRs chr13100310212 100310842 7.47E−06 24.45238095 Hyper-methylated PCa|NT DMRschr13 100568076 100578586 0.001969641 −40.21238095 Hypo-methylatedPCa|NT DMRs chr13 100624234 100630385 1.99E−12 34.40357143Hyper-methylated PCa|NT DMRs chr13 100740393 100740481 0.001969641−56.45634921 Hypo-methylated PCa|NT DMRs chr13 101173580 1011740975.20E−08 27.04761905 Hyper-methylated PCa|NT DMRs chr13 101186116101197410 1.42E−05 −45.65306122 Hypo-methylated PCa|NT DMRs chr13102431388 102532842 0.000354065 −31.2026455 Hypo-methylated PCa|NT DMRschr13 102580006 102888822 1.57E−10 −32.75416667 Hypo-methylated PCa|NTDMRs chr13 102892803 103042408 6.17E−06 −37.39087302 Hypo-methylatedPCa|NT DMRs chr13 103088596 103203949 1.76E−06 −42.80952381Hypo-methylated PCa|NT DMRs chr13 103344517 103366455 2.42E−05−26.54931973 Hypo-methylated PCa|NT DMRs chr13 106062676 1060627546.42E−05 −23.06137566 Hypo-methylated PCa|NT DMRs chr13 107069338107069987 0.002373155 36.31481481 Hyper-methylated PCa|NT DMRs chr13107799764 108506793 5.09E−20 −31.1021164 Hypo-methylated PCa|NT DMRschr13 108535715 108831780 4.54E−14 −34.68590865 Hypo-methylated PCa|NTDMRs chr13 108922481 108922544 0.001969641 33.88095238 Hyper-methylatedPCa|NT DMRs chr13 109148894 109148956 1.97E−05 22.91428571Hyper-methylated PCa|NT DMRs chr13 110512413 110522309 9.48E−0725.31972789 Hyper-methylated PCa|NT DMRs chr13 110781664 1107840412.12E−05 −29.52095238 Hypo-methylated PCa|NT DMRs chr13 110831650110835962 9.20E−10 −28.10568356 Hypo-methylated PCa|NT DMRs chr13110958690 110958946 0.000117699 23.66233766 Hyper-methylated PCa|NT DMRschr13 111070350 111072546 0.00064571  −28.77959184 Hypo-methylatedPCa|NT DMRs chr13 111106961 111107586 5.99E−05 −29.33919414Hypo-methylated PCa|NT DMRs chr13 111159575 111160475 0.001310211−46.35714286 Hypo-methylated PCa|NT DMRs chr13 111179796 1111800800.001969641 −25.8531746 Hypo-methylated PCa|NT DMRs chr13 111268715111278546 9.54E−05 −36.89409524 Hypo-methylated PCa|NT DMRs chr13111316634 111318855 3.28E−05 21.03380952 Hyper-methylated PCa|NT DMRschr13 111445615 111466230 9.06E−06 25.47261905 Hyper-methylated PCa|NTDMRs chr13 111684037 111697266 6.42E−05 −24.94444444 Hypo-methylatedPCa|NT DMRs chr13 111718993 111719267 5.71E−06 40.0264881Hyper-methylated PCa|NT DMRs chr13 112061914 112062903 2.85E−05−38.93040293 Hypo-methylated PCa|NT DMRs chr13 112063644 1121131235.72E−07 −21.59313037 Hypo-methylated PCa|NT DMRs chr13 112278837112285475 1.97E−05 −54.23619048 Hypo-methylated PCa|NT DMRs chr13112323193 112326118 1.42E−05 −26.15986395 Hypo-methylated PCa|NT DMRschr13 112329989 112330268 0.001969641 35.67063492 Hyper-methylatedPCa|NT DMRs chr13 112612375 112630338 1.11E−11 −28.10482625Hypo-methylated PCa|NT DMRs chr13 112630698 112706654 5.88E−18−28.87562657 Hypo-methylated PCa|NT DMRs chr13 112837680 1128377440.005968871 33.91428571 Hyper-methylated PCa|NT DMRs chr13 112996346112997267 0.000271988 −22.75714286 Hypo-methylated PCa|NT DMRs chr13112997608 113000429 0.000406444 −24.71142857 Hypo-methylated PCa|NT DMRschr13 113011051 113018381 0.001969641 −37.26190476 Hypo-methylatedPCa|NT DMRs chr13 113079481 113099478 0.005892073 −21.17891156Hypo-methylated PCa|NT DMRs chr13 113528544 113528678 3.61E−0538.41836735 Hyper-methylated PCa|NT DMRs chr13 113547154 1135472470.002086072 23.58333333 Hyper-methylated PCa|NT DMRs chr13 113556662113557493 0.000260936 −28.44952381 Hypo-methylated PCa|NT DMRs chr13113641885 113642543 0.008908019 27.65714286 Hyper-methylated PCa|NT DMRschr13 113689112 113689801 0.004095673 −27.67857143 Hypo-methylatedPCa|NT DMRs chr13 113765274 113765398 8.80E−08 27.18452381Hyper-methylated PCa|NT DMRs chr13 113807311 113807971 2.87E−1031.33791887 Hyper-methylated PCa|NT DMRs chr13 113979880 1139803944.18E−09 −39.16666667 Hypo-methylated PCa|NT DMRs chr13 114055864114056576 3.64E−05 −24.68073593 Hypo-methylated PCa|NT DMRs chr13114064623 114065183 3.10E−09 −31.97845805 Hypo-methylated PCa|NT DMRschr13 114075216 114075871 0.00208105  −20.45378151 Hypo-methylatedPCa|NT DMRs chr13 114091590 114091770 0.004095673 −46.3531746Hypo-methylated PCa|NT DMRs chr13 114102901 114105415 0.000117699−36.65021645 Hypo-methylated PCa|NT DMRs chr13 114145943 1141462330.001083007 28.79285714 Hyper-methylated PCa|NT DMRs chr13 114184420114184510 0.001969641 40.02380952 Hyper-methylated PCa|NT DMRs chr13114214648 114215140 0.000510004 −21.59714286 Hypo-methylated PCa|NT DMRschr13 114429454 114429609 0.009382828 −25.04232804 Hypo-methylatedPCa|NT DMRs chr13 114439188 114439618 0.003391914 27.94497354Hyper-methylated PCa|NT DMRs chr13 114450316 114450423 0.00014509429.40595238 Hyper-methylated PCa|NT DMRs chr13 114467102 1144673595.94E−06 −26.09307359 Hypo-methylated PCa|NT DMRs chr13 114496122114496429 0.005513661 −33.00952381 Hypo-methylated PCa|NT DMRs chr13114507064 114507393 3.05E−06 −20.9047619 Hypo-methylated PCa|NT DMRschr13 114514329 114515665 8.83E−06 −26.17432712 Hypo-methylated PCa|NTDMRs chr13 114515714 114518296 1.37E−06 −28.7032967 Hypo-methylatedPCa|NT DMRs chr13 114519669 114519709 0.00179283  40.26964286Hyper-methylated PCa|NT DMRs chr13 114519915 114520039 0.00641359 −23.86111111 Hypo-methylated PCa|NT DMRs chr13 114549606 1145498530.001969641 34.61564626 Hyper-methylated PCa|NT DMRs chr13 114559758114559971 0.005968871 −63.02857143 Hypo-methylated PCa|NT DMRs chr13114565894 114566687 1.76E−12 27.95772595 Hyper-methylated PCa|NT DMRschr13 114740004 114740618 3.42E−06 −57.12946429 Hypo-methylated PCa|NTDMRs chr13 114764602 114765478 0.000632596 −21.68571429 Hypo-methylatedPCa|NT DMRs chr13 114826043 114826549 7.78E−09 −24.20851371Hypo-methylated PCa|NT DMRs chr13 114828436 114829497 0.00198587441.84619048 Hyper-methylated PCa|NT DMRs chr13 114831687 1148349237.06E−07 30.8265873 Hyper-methylated PCa|NT DMRs chr13 114847300114847659 0.001969641 −42.60204082 Hypo-methylated PCa|NT DMRs chr13114875869 114876391 3.92E−06 38.03896104 Hyper-methylated PCa|NT DMRschr13 114894088 114897135 0.008243355 22.02298137 Hyper-methylatedPCa|NT DMRs chr14 20898057 20898224 1.97E−05 47.77619048Hyper-methylated PCa|NT DMRs chr14 21069688 21069928 1.76E−0635.69047619 Hyper-methylated PCa|NT DMRs chr14 21091062 210941583.69E−05 26.62545156 Hyper-methylated PCa|NT DMRs chr14 2197987221983833 0.004178506 −26.5327381 Hypo-methylated PCa|NT DMRs chr1423270004 23270131 0.001181579 38.89591837 Hyper-methylated PCa|NT DMRschr14 23276073 23290620 0.005513661 −21.32916667 Hypo-methylated PCa|NTDMRs chr14 23583383 23588172 7.86E−08 28.79858907 Hyper-methylatedPCa|NT DMRs chr14 23611367 23623810 0.00064571  −38.03174603Hypo-methylated PCa|NT DMRs chr14 23821229 23821446 3.05E−06 33.53479853Hyper-methylated PCa|NT DMRs chr14 23834789 23835756 4.47E−0932.95767196 Hyper-methylated PCa|NT DMRs chr14 24540025 245404150.005513661 28.04081633 Hyper-methylated PCa|NT DMRs chr14 2478043424780905 4.17E−06 30.66265664 Hyper-methylated PCa|NT DMRs chr1424808422 24809179 1.92E−12 38.33552381 Hyper-methylated PCa|NT DMRschr14 24837540 24838170 3.97E−13 34.00069686 Hyper-methylated PCa|NTDMRs chr14 24951105 24951258 0.005968871 44.77142857 Hyper-methylatedPCa|NT DMRs chr14 26725518 27062728 1.29E−07 −35.31746032Hypo-methylated PCa|NT DMRs chr14 29772983 29952738 0.001076343−34.7978355 Hypo-methylated PCa|NT DMRs chr14 30646231 307912760.000783791 −35.39380952 Hypo-methylated PCa|NT DMRs chr14 3089376330897658 0.005968871 −26.72952381 Hypo-methylated PCa|NT DMRs chr1431159737 31159787 0.005968871 −22.45714286 Hypo-methylated PCa|NT DMRschr14 31344151 31345058 0.000157373 25.3452381 Hyper-methylated PCa|NTDMRs chr14 32950619 32979137 0.00051204  −50.03571429 Hypo-methylatedPCa|NT DMRs chr14 34268920 34270337 6.88E−16 26.18995671Hyper-methylated PCa|NT DMRs chr14 34418609 34419838 0.00033962723.91119048 Hyper-methylated PCa|NT DMRs chr14 35020778 350212860.001181579 −24.65170068 Hypo-methylated PCa|NT DMRs chr14 3867864838680856 5.59E−12 30.71679198 Hyper-methylated PCa|NT DMRs chr1440933321 41599372 2.95E−13 −28.12945326 Hypo-methylated PCa|NT DMRschr14 41878730 42040754 0.003159484 −25.34603175 Hypo-methylated PCa|NTDMRs chr14 42074561 42075407 4.19E−06 26.5978836 Hyper-methylated PCa|NTDMRs chr14 43046504 43817028 9.21E−23 −28.41696429 Hypo-methylatedPCa|NT DMRs chr14 44854012 45221580 2.68E−17 −27.98486395Hypo-methylated PCa|NT DMRs chr14 45268046 45343117 0.000176046−29.1004329 Hypo-methylated PCa|NT DMRs chr14 48096085 48142684 1.46E−10−30.18301158 Hypo-methylated PCa|NT DMRs chr14 50155167 501553310.000396159 29.18428571 Hyper-methylated PCa|NT DMRs chr14 5125197451252499 0.009461608 24.81309524 Hyper-methylated PCa|NT DMRs chr1451410501 51410922 4.79E−06 24.05416667 Hyper-methylated PCa|NT DMRschr14 51974848 51975014 0.00023371  41.67532468 Hyper-methylated PCa|NTDMRs chr14 52218930 52219392 5.42E−05 −36.96825397 Hypo-methylatedPCa|NT DMRs chr14 52509589 52518560 0.007959104 −37.26394558Hypo-methylated PCa|NT DMRs chr14 54686140 54687028 3.85E−08 22.74421769Hyper-methylated PCa|NT DMRs chr14 54732013 54810795 1.43E−05−30.59642857 Hypo-methylated PCa|NT DMRs chr14 55120606 551208610.009503366 34.15357143 Hyper-methylated PCa|NT DMRs chr14 5558332255596561 6.41E−23 22.535 Hyper-methylated PCa|NT DMRs chr14 5590719955907375 1.24E−05 24.73361345 Hyper-methylated PCa|NT DMRs chr1456471819 56471887 0.005968871 22.65714286 Hyper-methylated PCa|NT DMRschr14 58484871 58593799 0.006976128 −25.47703081 Hypo-methylated PCa|NTDMRs chr14 60043077 60043556 4.20E−06 20.7443609 Hyper-methylated PCa|NTDMRs chr14 60794382 60795094 9.06E−13 21.71138211 Hyper-methylatedPCa|NT DMRs chr14 61032090 61032402 0.005968871 −44.86666667Hypo-methylated PCa|NT DMRs chr14 61118385 61119886 7.00E−11 39.48065476Hyper-methylated PCa|NT DMRs chr14 61654904 61655229 0.00068166 24.5031746 Hyper-methylated PCa|NT DMRs chr14 62035355 62035512 1.35E−0938.19047619 Hyper-methylated PCa|NT DMRs chr14 64208014 642158470.000333533 −40.14319728 Hypo-methylated PCa|NT DMRs chr14 6458014464580232 0.005968871 −59.25714286 Hypo-methylated PCa|NT DMRs chr1465007847 65009126 8.08E−07 29.63251232 Hyper-methylated PCa|NT DMRschr14 65172415 65172612 5.94E−06 50.66233766 Hyper-methylated PCa|NTDMRs chr14 65186709 65188402 6.42E−05 −32.06349206 Hypo-methylatedPCa|NT DMRs chr14 65438225 65438378 0.001115302 26.85416667Hyper-methylated PCa|NT DMRs chr14 65749247 65754508 0.00011508526.89223058 Hyper-methylated PCa|NT DMRs chr14 67955189 679554740.001969641 52.78571429 Hyper-methylated PCa|NT DMRs chr14 6828398468283999 0.008482405 46.66190476 Hyper-methylated PCa|NT DMRs chr1468750407 68750507 0.005968871 55.28095238 Hyper-methylated PCa|NT DMRschr14 69095026 69095336 9.06E−13 33.7358885 Hyper-methylated PCa|NT DMRschr14 69158048 69170010 0.001907648 23.45952381 Hyper-methylated PCa|NTDMRs chr14 69395207 69396145 0.005438982 29.3047619 Hyper-methylatedPCa|NT DMRs chr14 69402596 69403049 0.003871035 −24.16071429Hypo-methylated PCa|NT DMRs chr14 69813636 69813782 0.00196964140.07142857 Hyper-methylated PCa|NT DMRs chr14 70039398 700400201.54E−18 22.77529412 Hyper-methylated PCa|NT DMRs chr14 7012524370125430 0.005968871 −49.28571429 Hypo-methylated PCa|NT DMRs chr1470653765 70654671 3.23E−07 21.43537415 Hyper-methylated PCa|NT DMRschr14 70756046 70756121 0.000205174 43.43452381 Hyper-methylated PCa|NTDMRs chr14 71583517 71583703 0.005968871 −43.2 Hypo-methylated PCa|NTDMRs chr14 72239539 72318581 3.74E−06 −26.53869048 Hypo-methylatedPCa|NT DMRs chr14 72357011 72375125 0.005968871 −37.61428571Hypo-methylated PCa|NT DMRs chr14 72425642 72938442 8.50E−20−31.36443641 Hypo-methylated PCa|NT DMRs chr14 72946891 730724803.29E−12 −30.92325397 Hypo-methylated PCa|NT DMRs chr14 7308237673177392 1.65E−19 −37.25628816 Hypo-methylated PCa|NT DMRs chr1474177956 74180312 0.000487946 33.75666667 Hyper-methylated PCa|NT DMRschr14 74409083 74409329 0.007959104 28.85714286 Hyper-methylated PCa|NTDMRs chr14 74438909 74462826 0.000494377 −26.59727891 Hypo-methylatedPCa|NT DMRs chr14 74725151 74725348 0.003032307 27.21972789Hyper-methylated PCa|NT DMRs chr14 74769976 74770137 0.004947537−27.86772487 Hypo-methylated PCa|NT DMRs chr14 75342756 753428820.005968871 40.13809524 Hyper-methylated PCa|NT DMRs chr14 7540851175408957 0.003391914 37.43544974 Hyper-methylated PCa|NT DMRs chr1475800254 75801077 1.02E−09 51.41878307 Hyper-methylated PCa|NT DMRschr14 75893926 75894395 1.63E−07 25.11520737 Hyper-methylated PCa|NTDMRs chr14 76006589 76009568 0.007560755 28.16320346 Hyper-methylatedPCa|NT DMRs chr14 76600683 76600792 0.000481535 −27.38994709Hypo-methylated PCa|NT DMRs chr14 76939917 76940337 0.00253492821.31666667 Hyper-methylated PCa|NT DMRs chr14 77422419 774227380.003892896 43.81428571 Hyper-methylated PCa|NT DMRs chr14 7742806077428383 4.28E−07 20.27969925 Hyper-methylated PCa|NT DMRs chr1477434995 77435580 0.003314163 −35.95714286 Hypo-methylated PCa|NT DMRschr14 77489712 77493458 3.96E−32 −49.91744792 Hypo-methylated PCa|NTDMRs chr14 78432683 78432797 0.000215387 31.78571429 Hyper-methylatedPCa|NT DMRs chr14 79111674 79111760 0.004095673 −22.5 Hypo-methylatedPCa|NT DMRs chr14 79746628 79746781 0.000205174 22.07440476Hyper-methylated PCa|NT DMRs chr14 81433721 81439725 0.002141488−32.32380952 Hypo-methylated PCa|NT DMRs chr14 82296042 824783303.47E−05 −30.86412698 Hypo-methylated PCa|NT DMRs chr14 8351542083666727 1.38E−13 −30.69813259 Hypo-methylated PCa|NT DMRs chr1483703627 84283285 3.64E−17 −32.36137566 Hypo-methylated PCa|NT DMRschr14 84484112 84484266 0.001969641 −45.95918367 Hypo-methylated PCa|NTDMRs chr14 89493240 89493318 0.00015047  33.56043956 Hyper-methylatedPCa|NT DMRs chr14 89631058 89644632 0.007959104 26.33265306Hyper-methylated PCa|NT DMRs chr14 89771438 89771499 0.005968871−29.03809524 Hypo-methylated PCa|NT DMRs chr14 89818887 898378300.003034084 −22.64795918 Hypo-methylated PCa|NT DMRs chr14 8997703589977212 0.001969641 29.90873016 Hyper-methylated PCa|NT DMRs chr1490967174 90967644 1.27E−08 45.66755952 Hyper-methylated PCa|NT DMRschr14 91287431 91287580 0.004095673 44.5 Hyper-methylated PCa|NT DMRschr14 91731083 91731425 0.006185293 23.37414966 Hyper-methylated PCa|NTDMRs chr14 91740414 91740866 5.52E−05 28.66233766 Hyper-methylatedPCa|NT DMRs chr14 91743406 91744282 0.001969641 −35.42857143Hypo-methylated PCa|NT DMRs chr14 91860314 91862979 0.007563547−25.54545455 Hypo-methylated PCa|NT DMRs chr14 91881488 918817886.42E−05 36.22751323 Hyper-methylated PCa|NT DMRs chr14 9241363392413768 1.35E−05 31.30340136 Hyper-methylated PCa|NT DMRs chr1492652091 92652216 0.001969641 29.12936508 Hyper-methylated PCa|NT DMRschr14 92680323 92691421 0.003391914 −21.37460317 Hypo-methylated PCa|NTDMRs chr14 92790439 92790508 9.41E−05 25.56410256 Hyper-methylatedPCa|NT DMRs chr14 92849470 92850047 0.000260936 −21.09333333Hypo-methylated PCa|NT DMRs chr14 92853140 92853227 0.00596887149.81904762 Hyper-methylated PCa|NT DMRs chr14 92980747 929811434.21E−07 27.4141369 Hyper-methylated PCa|NT DMRs chr14 93006310 930100770.001181579 35.11904762 Hyper-methylated PCa|NT DMRs chr14 9311555593125829 1.07E−06 39.0385034 Hyper-methylated PCa|NT DMRs chr14 9315325093154607 1.87E−28 −44.42589893 Hypo-methylated PCa|NT DMRs chr1493389695 93389744 0.000143553 20.52312925 Hyper-methylated PCa|NT DMRschr14 93412555 93413112 0.002044625 −43.60822511 Hypo-methylated PCa|NTDMRs chr14 93505152 93512934 0.002097193 31.20068027 Hyper-methylatedPCa|NT DMRs chr14 93827416 93885481 6.42E−05 −27.68518519Hypo-methylated PCa|NT DMRs chr14 93925461 93968616 0.000122432−25.78354978 Hypo-methylated PCa|NT DMRs chr14 94032483 940843045.86E−11 −23.36816327 Hypo-methylated PCa|NT DMRs chr14 9425375294254842 1.66E−11 31.65 Hyper-methylated PCa|NT DMRs chr14 9429103294291414 0.001451132 −21.89010989 Hypo-methylated PCa|NT DMRs chr1494360021 94360328 0.001969641 −32.01020408 Hypo-methylated PCa|NT DMRschr14 94467340 94470596 7.48E−05 −34.83915344 Hypo-methylated PCa|NTDMRs chr14 95237574 95244825 1.60E−19 34.16367521 Hyper-methylatedPCa|NT DMRs chr14 95403215 95403422 5.42E−05 −27.74246032Hypo-methylated PCa|NT DMRs chr14 95837370 95837624 3.66E−05 36.95047619Hyper-methylated PCa|NT DMRs chr14 95882539 95898749 0.005295761−36.07272727 Hypo-methylated PCa|NT DMRs chr14 95966492 959669170.000847246 −31.85457875 Hypo-methylated PCa|NT DMRs chr14 9624076596341008 0.00023938  −24.58853616 Hypo-methylated PCa|NT DMRs chr1496362466 96428783 2.37E−05 −33.07460317 Hypo-methylated PCa|NT DMRschr14 96520635 96521554 0.000205174 −27.15 Hypo-methylated PCa|NT DMRschr14 96707164 96728062 5.52E−05 −23.4914966 Hypo-methylated PCa|NT DMRschr14 96730215 96730456 0.00064571  −49.34693878 Hypo-methylated PCa|NTDMRs chr14 96735546 96735868 0.002767976 −20.94805195 Hypo-methylatedPCa|NT DMRs chr14 97093420 97093518 0.005968871 38.58952381Hyper-methylated PCa|NT DMRs chr14 97399081 97463882 6.29E−12−22.4707672 Hypo-methylated PCa|NT DMRs chr14 97492461 974942530.00064571  −45.04421769 Hypo-methylated PCa|NT DMRs ehrl4 9755687497683619 7.86E−08 −37.4287415 Hypo-methylated PCa|NT DMRs chr14 9769379198178276 1.27E−28 −36.62623907 Hypo-methylated PCa|NT DMRs chr1498224071 98455419 1.69E−13 −34.33189369 Hypo-methylated PCa|NT DMRschr14 99420764 99499551 4.18E−14 −29.09435626 Hypo-methylated PCa|NTDMRs chr14 99506229 99506674 1.42E−05 −31.6292517 Hypo-methylated PCa|NTDMRs chr14 99532758 99532894 1.76E−06 −34.33333333 Hypo-methylatedPCa|NT DMRs chr14 99658816 99658939 0.001969641 −33.87482993Hypo-methylated PCa|NT DMRs chr14 99711875 99711921 0.00196964128.02777778 Hyper-methylated PCa|NT DMRs chr14 100039827 1000436090.000807276 −35.15546218 Hypo-methylated PCa|NT DMRs chr14 100091467100091521 0.000377317 −31.11607143 Hypo-methylated PCa|NT DMRs chr14100125594 100130466 1.97E−06 27.67953394 Hyper-methylated PCa|NT DMRschr14 100133204 100146451 2.99E−05 22.55868726 Hyper-methylated PCa|NTDMRs chr14 100148295 100148363 0.005968871 −35.13333333 Hypo-methylatedPCa|NT DMRs chr14 100154773 100192812 0.001975917 25.26479076Hyper-methylated PCa|NT DMRs chr14 100201160 100201236 0.001969641 −44Hypo-methylated PCa|NT DMRs chr14 100212986 100213394 0.00057057625.57936508 Hyper-methylated PCa|NT DMRs chr14 100216292 1002166030.006589535 −28.68571429 Hypo-methylated PCa|NT DMRs chr14 100431319100437027 0.000494377 −42.68061224 Hypo-methylated PCa|NT DMRs chr14100496719 100537036 0.005968871 −34.8 Hypo-methylated PCa|NT DMRs chr14100621949 100622582 5.84E−05 −51.34960317 Hypo-methylated PCa|NT DMRschr14 100784369 100784847 5.86E−07 22.70539683 Hyper-methylated PCa|NTDMRs chr14 100859981 100883064 0.000132829 29.51753247 Hyper-methylatedPCa|NT DMRs chr14 100907114 100907317 0.005968871 −23.8 Hypo-methylatedPCa|NT DMRs chr14 100998266 101003027 0.000349171 22.61870748Hyper-methylated PCa|NT DMRs chr14 101033362 101033979 2.04E−0725.26836735 Hyper-methylated PCa|NT DMRs chr14 101106695 1011074340.000215808 50.96560847 Hyper-methylated PCa|NT DMRs chr14 101131254101132077 0.001969641 −49.31349206 Hypo-methylated PCa|NT DMRs chr14101172979 101173113 0.001111028 22.85449735 Hyper-methylated PCa|NT DMRschr14 101174591 101175667 8.23E−07 −34.67329932 Hypo-methylated PCa|NTDMRs chr14 101180323 101185461 0.009924186 20.81746032 Hyper-methylatedPCa|NT DMRs chr14 101189225 101190570 2.00E−08 −39.38095238Hypo-methylated PCa|NT DMRs chr14 101263229 101284415 2.61E−13−27.41028139 Hypo-methylated PCa|NT DMRs chr14 101294315 1012945080.003809353 −21.52857143 Hypo-methylated PCa|NT DMRs chr14 101301380101301859 4.10E−09 −27.96904762 Hypo-methylated PCa|NT DMRs chr14101302916 101311984 1.87E−08 −29.14583333 Hypo-methylated PCa|NT DMRschr14 101333924 101346783 1.13E−12 −26.03462033 Hypo-methylated PCa|NTDMRs chr14 101518296 101528649 2.01E−07 −30.74761905 Hypo-methylatedPCa|NT DMRs chr14 101538880 101539975 4.69E−05 −33.03630952Hypo-methylated PCa|NT DMRs chr14 101578313 101578423 0.00196964125.0952381 Hyper-methylated PCa|NT DMRs chr14 101579049 1015859909.27E−10 −26.77258687 Hypo-methylated PCa|NT DMRs chr14 101701119101713820 3.68E−08 −29.85205255 Hypo-methylated PCa|NT DMRs chr14101826486 101836746 0.000243232 −25.04696223 Hypo-methylated PCa|NT DMRschr14 102101382 102156939 1.95E−12 −21.61758242 Hypo-methylated PCa|NTDMRs chr14 102501541 102501768 0.001969641 −41.46031746 Hypo-methylatedPCa|NT DMRs chr14 102526995 102530115 0.000214774 −36.67719298Hypo-methylated PCa|NT DMRs chr14 102675913 102680519 0.00084529329.67785714 Hyper-methylated PCa|NT DMRs chr14 102681469 1026817121.97E−05 −55.14857143 Hypo-methylated PCa|NT DMRs chr14 102964809102964952 0.001423532 −21.95238095 Hypo-methylated PCa|NT DMRs chr14103389944 103390410 0.000175619 21.4021164 Hyper-methylated PCa|NT DMRschr14 103394344 103395725 6.38E−27 22.46471088 Hyper-methylated PCa|NTDMRs chr14 103560935 103561069 0.003448944 29.23809524 Hyper-methylatedPCa|NT DMRs chr14 103592992 103594052 1.96E−05 −37.77962963Hypo-methylated PCa|NT DMRs chr14 103603330 103603648 4.90E−0639.20357143 Hyper-methylated PCa|NT DMRs chr14 103604943 1036054228.71E−07 20.03581349 Hyper-methylated PCa|NT DMRs chr14 103745898103747391 9.29E−07 24.15250965 Hyper-methylated PCa|NT DMRs chr14103760337 103760870 0.005531225 −32.47354497 Hypo-methylated PCa|NT DMRschr14 104005066 104006787 0.000173442 −23.19345238 Hypo-methylatedPCa|NT DMRs chr14 104094770 104095033 0.001083007 26.81 Hyper-methylatedPCa|NT DMRs chr14 104159363 104164598 0.002360289 −31.95371429Hypo-methylated PCa|NT DMRs chr14 104330466 104334123 0.001083007−44.30857143 Hypo-methylated PCa|NT DMRs chr14 104338087 1043387891.66E−08 34.65026455 Hyper-methylated PCa|NT DMRs chr14 104339780104345945 0.000632596 −33.9327381 Hypo-methylated PCa|NT DMRs chr14104561302 104562380 1.48E−05 −27.57282913 Hypo-methylated PCa|NT DMRschr14 104563219 104567800 2.11E−06 −26.92216117 Hypo-methylated PCa|NTDMRs chr14 104596956 104600814 0.000234162 −25.85659341 Hypo-methylatedPCa|NT DMRs chr14 104609445 104610443 0.001129594 −32.19206349Hypo-methylated PCa|NT DMRs chr14 104622064 104622215 1.97E−05−35.89714286 Hypo-methylated PCa|NT DMRs chr14 104644569 1046464771.99E−07 −31.58864469 Hypo-methylated PCa|NT DMRs chr14 104689883104690998 1.55E−05 25.92070393 Hyper-methylated PCa|NT DMRs chr14104710740 104713530 2.06E−05 −25.73469388 Hypo-methylated PCa|NT DMRschr14 104741700 104749852 1.99E−07 −32.47943723 Hypo-methylated PCa|NTDMRs chr14 104757434 104761709 7.32E−09 −23.69530812 Hypo-methylatedPCa|NT DMRs chr14 104799385 104799420 0.005968871 25.2952381Hyper-methylated PCa|NT DMRs chr14 104799487 104801103 4.24E−07−21.35632184 Hypo-methylated PCa|NT DMRs chr14 104902476 1049028975.67E−06 23.53571429 Hyper-methylated PCa|NT DMRs chr14 105054923105055050 6.93E−06 −65.31428571 Hypo-methylated PCa|NT DMRs chr14105124904 105127312 0.000641983 26.11013825 Hyper-methylated PCa|NT DMRschr14 105144478 105144982 0.00064571  34.25809524 Hyper-methylatedPCa|NT DMRs chr14 105148179 105148235 0.008482405 −30.84571429Hypo-methylated PCa|NT DMRs chr14 105153420 105153951 0.00339191433.93915344 Hyper-methylated PCa|NT DMRs chr14 105154445 1051553289.85E−08 −37.74497354 Hypo-methylated PCa|NT DMRs chr14 105166964105167415 1.97E−05 30.88142857 Hyper-methylated PCa|NT DMRs chr14105236410 105240179 0.000196948 −20.77514881 Hypo-methylated PCa|NT DMRschr14 105252117 105252339 0.000179253 20.18681319 Hyper-methylatedPCa|NT DMRs chr14 105267701 105269175 0.001971273 −26.14502165Hypo-methylated PCa|NT DMRs chr14 105330015 105330536 0.00025637 27.56428571 Hyper-methylated PCa|NT DMRs chr14 105393144 1053932330.000205174 31.17857143 Hyper-methylated PCa|NT DMRs chr14 105398331105398969 4.00E−11 −22.1237037 Hypo-methylated PCa|NT DMRs chr14105399027 105399342 0.007716412 −20.24671202 Hypo-methylated PCa|NT DMRschr14 105435058 105444127 2.83E−05 −22.03103175 Hypo-methylated PCa|NTDMRs chr14 105446449 105446720 1.42E−05 −47.31802721 Hypo-methylatedPCa|NT DMRs chr14 105525052 105528266 2.69E−13 40.76634383Hyper-methylated PCa|NT DMRs chr14 105543326 105543602 0.00418787534.03333333 Hyper-methylated PCa|NT DMRs chr14 105557746 1055580691.97E−05 −45.85095238 Hypo-methylated PCa|NT DMRs chr14 105633611105633819 4.82E−06 24.76455026 Hyper-methylated PCa|NT DMRs chr14105655398 105657755 0.001391421 −23.21255411 Hypo-methylated PCa|NT DMRschr14 105687906 105688130 0.000278967 −59.5003663 Hypo-methylated PCa|NTDMRs chr14 105715867 105716237 0.000293608 −28.92121212 Hypo-methylatedPCa|NT DMRs chr14 105750529 105750614 0.00064571  49.71428571Hyper-methylated PCa|NT DMRs chr14 105880799 105881035 0.00423697435.22142857 Hyper-methylated PCa|NT DMRs chr14 105888433 1058896598.30E−05 42.05026455 Hyper-methylated PCa|NT DMRs chr14 105935708105936452 6.32E−05 26.29241071 Hyper-methylated PCa|NT DMRs chr14105948819 105949229 0.005438982 −21.40714286 Hypo-methylated PCa|NT DMRschr14 106016106 106016165 1.97E−05 −32.8947619 Hypo-methylated PCa|NTDMRs chr14 106344670 106348320 6.45E−05 34.8719888 Hyper-methylatedPCa|NT DMRs chr14 106356880 106366615 6.88E−08 22.54772979Hyper-methylated PCa|NT DMRs chr14 106734078 106743505 0.003314163−27.45714286 Hypo-methylated PCa|NT DMRs chr15 22029069 220420051.97E−05 −27.96857143 Hypo-methylated PCa|NT DMRs chr15 2254482222545409 3.19E−07 −31.08333333 Hypo-methylated PCa|NT DMRs chr1522825759 22828255 0.000189331 −24.98484848 Hypo-methylated PCa|NT DMRschr15 23032582 23032910 1.97E−05 −32.14285714 Hypo-methylated PCa|NTDMRs chr15 23807225 23807592 2.41E−08 27.52070393 Hyper-methylatedPCa|NT DMRs chr15 23888054 23891916 6.37E−06 −29.03980952Hypo-methylated PCa|NT DMRs chr15 24726006 24784826 3.17E−07−28.45897436 Hypo-methylated PCa|NT DMRs chr15 24943606 249928080.000339757 −25.63982684 Hypo-methylated PCa|NT DMRs chr15 2514342325200049 6.20E−09 −20.78188153 Hypo-methylated PCa|NT DMRs chr1526043821 26044589 0.006950763 30.3004329 Hyper-methylated PCa|NT DMRschr15 26193752 26221074 5.94E−06 −27.41774892 Hypo-methylated PCa|NTDMRs chr15 26263104 26302167 9.83E−09 −28.70770308 Hypo-methylatedPCa|NT DMRs chr15 26665873 26846396 0.001391421 −27.20562771Hypo-methylated PCa|NT DMRs chr15 27137410 27139864 1.92E−07 21.35371763Hyper-methylated PCa|NT DMRs chr15 28070895 28070986 0.005968871−20.25714286 Hypo-methylated PCa|NT DMRs chr15 28753762 287538130.00097807  24.37312925 Hyper-methylated PCa|NT DMRs chr15 2913032329130754 0.00064571  24.98148148 Hyper-methylated PCa|NT DMRs chr1529423922 29424197 0.00068166  51.28869048 Hyper-methylated PCa|NT DMRschr15 29572935 29573057 0.005968871 25.65714286 Hyper-methylated PCa|NTDMRs chr15 29967397 29968617 0.000286492 24.1484127 Hyper-methylatedPCa|NT DMRs chr15 31476380 31499290 0.001604291 −21.69285714Hypo-methylated PCa|NT DMRs chr15 31508622 31516120 0.00289443823.05993432 Hyper-methylated PCa|NT DMRs chr15 31603919 316047480.00641359  −21.97619048 Hypo-methylated PCa|NT DMRs chr15 3163078131658358 4.24E−07 22.9412415 Hyper-methylated PCa|NT DMRs chr15 3168472331685698 0.00018587  35.68354978 Hyper-methylated PCa|NT DMRs chr1534636940 34654458 1.78E−08 −20.31873016 Hypo-methylated PCa|NT DMRschr15 35014197 35014660 1.66E−07 41.70562771 Hyper-methylated PCa|NTDMRs chr15 35363399 35363504 0.001969641 34.07619048 Hyper-methylatedPCa|NT DMRs chr15 37172485 37181088 2.66E−13 25.88128307Hyper-methylated PCa|NT DMRs chr15 37697605 37874682 2.45E−07−26.89047619 Hypo-methylated PCa|NT DMRs chr15 37921054 381170400.00083549  −26.3215873 Hypo-methylated PCa|NT DMRs chr15 3812631838155343 0.005968871 −33.45428571 Hypo-methylated PCa|NT DMRs chr1539160002 39160211 0.00641359  28.16825397 Hyper-methylated PCa|NT DMRschr15 39874437 39874777 0.000339627 −21.46428571 Hypo-methylated PCa|NTDMRs chr15 40268678 40269241 0.000651745 −44.16746032 Hypo-methylatedPCa|NT DMRs chr15 40314882 40329305 0.004947537 −22.45449735Hypo-methylated PCa|NT DMRs chr15 40348308 40362086 2.28E−06−35.56289683 Hypo-methylated PCa|NT DMRs chr15 40395837 403960220.001969641 −58.74047619 Hypo-methylated PCa|NT DMRs chr15 4057603440576117 0.008234951 26.96666667 Hyper-methylated PCa|NT DMRs chr1540627374 40627503 8.17E−05 −32.33766234 Hypo-methylated PCa|NT DMRschr15 40628591 40629344 0.007560755 27.81607143 Hyper-methylated PCa|NTDMRs chr15 40738481 40745036 0.001241245 22.26984127 Hyper-methylatedPCa|NT DMRs chr15 41075917 41080617 0.007560755 −32.58614719Hypo-methylated PCa|NT DMRs chr15 41165191 41165916 0.006148156−23.32922824 Hypo-methylated PCa|NT DMRs chr15 41194603 411954874.39E−08 45.56604555 Hyper-methylated PCa|NT DMRs chr15 4121754441218725 2.67E−16 28.69387755 Hyper-methylated PCa|NT DMRs chr1541232703 41232933 0.005968871 34.34285714 Hyper-methylated PCa|NT DMRschr15 41252097 41252982 0.004553481 25.41587302 Hyper-methylated PCa|NTDMRs chr15 42173883 42174854 5.95E−10 31.66821705 Hyper-methylatedPCa|NT DMRs chr15 42185156 42185257 0.000205174 29.94940476Hyper-methylated PCa|NT DMRs chr15 42447729 42470990 3.11E−05−32.25066667 Hypo-methylated PCa|NT DMRs chr15 42652080 426595022.85E−05 40.48717949 Hyper-methylated PCa|NT DMRs chr15 4357949643580893 5.52E−05 −33.95021645 Hypo-methylated PCa|NT DMRs chr1544052919 44068997 3.62E−05 −23.72539683 Hypo-methylated PCa|NT DMRschr15 45467538 45479934 8.58E−13 30.99402428 Hyper-methylated PCa|NTDMRs chr15 45670456 45670952 2.74E−25 23.12908778 Hyper-methylatedPCa|NT DMRs chr15 45942458 45942549 0.005968871 38.7 Hyper-methylatedPCa|NT DMRs chr15 47292797 47392206 0.003448944 −31.8414966Hypo-methylated PCa|NT DMRs chr15 47477056 47477411 4.24E−06 29.00250627Hyper-methylated PCa|NT DMRs chr15 52000774 52000949 0.001969641−62.75510204 Hypo-methylated PCa|NT DMRs chr15 52551211 525747670.003314163 −23.25714286 Hypo-methylated PCa|NT DMRs chr15 5310584353328080 1.79E−06 −39.29952381 Hypo-methylated PCa|NT DMRs chr1553591585 53802443 5.10E−08 −33.66059113 Hypo-methylated PCa|NT DMRschr15 55590327 55600864 0.009924186 22.24338624 Hyper-methylated PCa|NTDMRs chr15 55806775 55806837 0.005968871 −30.99047619 Hypo-methylatedPCa|NT DMRs chr15 59157047 59157300 2.80E−05 29.71111111Hyper-methylated PCa|NT DMRs chr15 59730722 59730975 0.00658953521.04047619 Hyper-methylated PCa|NT DMRs chr15 60084450 600847050.003622801 −22.48809524 Hypo-methylated PCa|NT DMRs chr15 6023740960285810 0.000109889 −22.37983193 Hypo-methylated PCa|NT DMRs chr1562042951 62043314 0.001969641 −37.32857143 Hypo-methylated PCa|NT DMRschr15 62411153 62437557 0.007428376 −28.17802198 Hypo-methylated PCa|NTDMRs chr15 62456918 62457601 1.10E−09 21.52107143 Hyper-methylatedPCa|NT DMRs chr15 62510408 62511293 0.000205174 −29.41071429Hypo-methylated PCa|NT DMRs chr15 62720479 62720729 0.008482405−59.83333333 Hypo-methylated PCa|NT DMRs chr15 63189297 631895373.44E−06 −52.01785714 Hypo-methylated PCa|NT DMRs chr15 6319291663192973 0.001969641 28.36734694 Hyper-methylated PCa|NT DMRs chr1564447092 64453647 5.92E−05 −22.78428571 Hypo-methylated PCa|NT DMRschr15 64841547 64864948 0.001657405 23.48571429 Hyper-methylated PCa|NTDMRs chr15 65115885 65116069 0.005295761 24.59090909 Hyper-methylatedPCa|NT DMRs chr15 65135286 65137216 0.001969641 45.19047619Hyper-methylated PCa|NT DMRs chr15 65360510 65360538 0.00209719321.28571429 Hyper-methylated PCa|NT DMRs chr15 65597874 656119142.78E−05 −22.19627329 Hypo-methylated PCa|NT DMRs chr15 6570732565708988 0.007560755 −23.82142857 Hypo-methylated PCa|NT DMRs chr1565715408 65715515 1.06E−06 21.35064935 Hyper-methylated PCa|NT DMRschr15 66473053 66483605 0.001391421 −26.30562771 Hypo-methylated PCa|NTDMRs chr15 66648693 66648786 0.004057568 25.61904762 Hyper-methylatedPCa|NT DMRs chr15 66790377 66792977 0.005375157 −21.93503401Hypo-methylated PCa|NT DMRs chr15 66922915 66930993 0.00038604131.30505952 Hyper-methylated PCa|NT DMRs chr15 66939822 669400000.001969641 −30.8 Hypo-methylated PCa|NT DMRs chr15 66941645 669430460.001969641 −53.49206349 Hypo-methylated PCa|NT DMRs chr15 6696586466965923 0.005968871 47.93809524 Hyper-methylated PCa|NT DMRs chr1567413302 67413801 1.36E−05 44.53741497 Hyper-methylated PCa|NT DMRschr15 68116472 68116935 2.80E−05 22.32063492 Hyper-methylated PCa|NTDMRs chr15 68498070 68502604 0.001391421 25.22789116 Hyper-methylatedPCa|NT DMRs chr15 70354718 70354835 6.94E−06 −47.44761905Hypo-methylated PCa|NT DMRs chr15 70641449 70641603 0.00064571 51.0122449 Hyper-methylated PCa|NT DMRs chr15 70740904 707448560.004794367 29.18367347 Hyper-methylated PCa|NT DMRs chr15 7150701271529969 0.001047828 22.50576441 Hyper-methylated PCa|NT DMRs chr1572472500 72472793 0.004149771 −37.76923077 Hypo-methylated PCa|NT DMRschr15 72519739 72520689 0.001969641 36.27063492 Hyper-methylated PCa|NTDMRs chr15 72668088 72669048 5.76E−11 41.44086022 Hyper-methylatedPCa|NT DMRs chr15 72979666 72979871 0.000974795 −28.02678571Hypo-methylated PCa|NT DMRs chr15 73611223 73611529 3.39E−07 25.79911817Hyper-methylated PCa|NT DMRs chr15 73617793 73617969 6.42E−0524.41269841 Hyper-methylated PCa|NT DMRs chr15 74215872 742192081.19E−05 26.03219048 Hyper-methylated PCa|NT DMRs chr15 7423428574244344 0.002082381 27.4789916 Hyper-methylated PCa|NT DMRs chr1574249177 74249231 0.000974795 22.94642857 Hyper-methylated PCa|NT DMRschr15 74400269 74419179 0.000242379 −28.42666667 Hypo-methylated PCa|NTDMRs chr15 74484446 74484870 0.000392715 −24.98095238 Hypo-methylatedPCa|NT DMRs chr15 74564053 74591576 6.02E−06 −26.46252588Hypo-methylated PCa|NT DMRs chr15 74658079 74658466 3.09E−12 29.84555985Hyper-methylated PCa|NT DMRs chr15 75018814 75019336 0.00355142 27.76007326 Hyper-methylated PCa|NT DMRs chr15 75069591 750697610.000205174 56.06845238 Hyper-methylated PCa|NT DMRs chr15 7521304075213089 0.005968871 35.85714286 Hyper-methylated PCa|NT DMRs chr1575251061 75254698 2.48E−08 31.83384813 Hyper-methylated PCa|NT DMRschr15 75470918 75471350 2.24E−14 38.82336656 Hyper-methylated PCa|NTDMRs chr15 75614969 75620496 6.69E−05 −20.72261905 Hypo-methylatedPCa|NT DMRs chr15 75940744 75941919 0.001795658 −20.96645022Hypo-methylated PCa|NT DMRs chr15 75969571 75974521 0.001836557−23.29304029 Hypo-methylated PCa|NT DMRs chr15 76257288 762574910.00064571  −66.26530612 Hypo-methylated PCa|NT DMRs chr15 7648405176487308 9.19E−10 32.96597403 Hyper-methylated PCa|NT DMRs chr1577271846 77271970 0.005968871 −24.34761905 Hypo-methylated PCa|NT DMRschr15 77861900 77862131 0.000176046 25.7012987 Hyper-methylated PCa|NTDMRs chr15 77874305 77874698 0.003032307 −24.3792517 Hypo-methylatedPCa|NT DMRs chr15 77949978 77952727 0.001899053 −24.6302521Hypo-methylated PCa|NT DMRs chr15 78090566 78090777 0.00068166 −35.64464286 Hypo-methylated PCa|NT DMRs chr15 78108412 781112521.32E−05 24.08378926 Hyper-methylated PCa|NT DMRs chr15 7816329778163822 0.004095673 −35.88095238 Hypo-methylated PCa|NT DMRs chr1578235966 78237083 1.13E−08 23.22563025 Hyper-methylated PCa|NT DMRschr15 78911719 78912591 7.68E−06 23.06105006 Hyper-methylated PCa|NTDMRs chr15 79122995 79123539 1.92E−11 37.98126294 Hyper-methylatedPCa|NT DMRs chr15 79471392 79497517 7.44E−05 −30.37936508Hypo-methylated PCa|NT DMRs chr15 79502068 79502228 0.00020517437.28452381 Hyper-methylated PCa|NT DMRs chr15 79725328 797439770.009069241 26.00779221 Hyper-methylated PCa|NT DMRs chr15 8224746882306639 0.007560755 −20.01071429 Hypo-methylated PCa|NT DMRs chr1583317801 83331629 0.001969641 −26.45442177 Hypo-methylated PCa|NT DMRschr15 84748595 84748733 6.99E−08 20.45341615 Hyper-methylated PCa|NTDMRs chr15 84923577 84946482 0.005968871 −27.78095238 Hypo-methylatedPCa|NT DMRs chr15 85145308 85145478 0.000205174 −32.28571429Hypo-methylated PCa|NT DMRs chr15 85398294 85398498 0.005968871−61.98095238 Hypo-methylated PCa|NT DMRs chr15 87182868 874150200.009084137 −20.87179487 Hypo-methylated PCa|NT DMRs chr15 8752288088296924 1.63E−17 −29.88275862 Hypo-methylated PCa|NT DMRs chr1588447542 88522657 1.60E−13 −25.25228175 Hypo-methylated PCa|NT DMRschr15 88596574 88621644 1.16E−05 −22.45192744 Hypo-methylated PCa|NTDMRs chr15 88649335 88749293 5.23E−09 −30.45780731 Hypo-methylatedPCa|NT DMRs chr15 88842943 88939251 7.48E−08 −31.36912442Hypo-methylated PCa|NT DMRs chr15 89174997 89175108 0.004095673−67.37619048 Hypo-methylated PCa|NT DMRs chr15 89182658 891828110.00064571  −25.92857143 Hypo-methylated PCa|NT DMRs chr15 8920043189246883 3.02E−07 −30.17417582 Hypo-methylated PCa|NT DMRs chr1589254550 89273482 0.001241245 −27.47883598 Hypo-methylated PCa|NT DMRschr15 89438128 89442224 4.04E−12 23.12242063 Hyper-methylated PCa|NTDMRs chr15 89455546 89455938 0.000122432 41.36580087 Hyper-methylatedPCa|NT DMRs chr15 89682168 89691275 0.002568162 −20.08253968Hypo-methylated PCa|NT DMRs chr15 89903447 89903705 3.63E−06 30.87328042Hyper-methylated PCa|NT DMRs chr15 89905949 89906200 5.36E−0622.40761905 Hyper-methylated PCa|NT DMRs chr15 90320205 903206359.08E−07 28.35497835 Hyper-methylated PCa|NT DMRs chr15 9034545690347438 0.00064571  31.29251701 Hyper-methylated PCa|NT DMRs chr1590608490 90609864 0.005685126 30.23992674 Hyper-methylated PCa|NT DMRschr15 90693374 90703780 0.000294557 −33.5952381 Hypo-methylated PCa|NTDMRs chr15 90717795 90717995 0.00023371  −55.99047619 Hypo-methylatedPCa|NT DMRs chr15 90727205 90728045 1.54E−05 −27.51316527Hypo-methylated PCa|NT DMRs chr15 90754353 90755501 0.00641001221.93290043 Hyper-methylated PCa|NT DMRs chr15 90768876 907718040.00025637  −21.3234127 Hypo-methylated PCa|NT DMRs chr15 9141347991414465 0.005513661 20.7952381 Hyper-methylated PCa|NT DMRs chr1591438912 91439061 0.001115302 −30.39285714 Hypo-methylated PCa|NT DMRschr15 91822078 92043600 6.55E−07 −25.92301587 Hypo-methylated PCa|NTDMRs chr15 92172082 92194203 0.00064571  −44.41904762 Hypo-methylatedPCa|NT DMRs chr15 92231226 92383271 8.32E−09 −35.70816327Hypo-methylated PCa|NT DMRs chr15 92884266 92930804 1.40E−05−31.58928571 Hypo-methylated PCa|NT DMRs chr15 93315575 933162900.002097193 −40.53061224 Hypo-methylated PCa|NT DMRs chr15 9335568493355890 0.001969641 −45.78571429 Hypo-methylated PCa|NT DMRs chr1593590747 93592053 0.003032307 30.83650794 Hyper-methylated PCa|NT DMRschr15 93664314 93687756 2.32E−06 −41.432493 Hypo-methylated PCa|NT DMRschr15 93700711 93715169 4.05E−06 −35.07857143 Hypo-methylated PCa|NTDMRs chr15 93881119 93897807 1.42E−05 −35.0452381 Hypo-methylated PCa|NTDMRs chr15 93958496 94006028 1.45E−08 −25.09396825 Hypo-methylatedPCa|NT DMRs chr15 94072338 94518572 4.61E−18 −29.1688254 Hypo-methylatedPCa|NT DMRs chr15 96170203 96170334 0.005968871 48.18761905Hyper-methylated PCa|NT DMRs chr15 96828892 96865061 0.00228045322.24302135 Hyper-methylated PCa|NT DMRs chr15 96865958 968668154.34E−11 30.44519141 Hyper-methylated PCa|NT DMRs chr15 9688457896899722 1.49E−13 25.76121032 Hyper-methylated PCa|NT DMRs chr1597977700 97992575 0.00064571  −36.29931973 Hypo-methylated PCa|NT DMRschr15 98836205 98836262 4.10E−07 21.92481203 Hyper-methylated PCa|NTDMRs chr15 99091076 99091263 0.004095673 42.92857143 Hyper-methylatedPCa|NT DMRs chr15 99289458 99289756 0.005968871 −32.44571429Hypo-methylated PCa|NT DMRs chr15 99488657 99489989 0.00108300728.66190476 Hyper-methylated PCa|NT DMRs chr15 99494842 994974650.003510453 −21.43877551 Hypo-methylated PCa|NT DMRs chr15 9996834799968608 0.000205174 −37.87202381 Hypo-methylated PCa|NT DMRs chr15100289436 100295420 0.009807302 −39.44238095 Hypo-methylated PCa|NT DMRschr15 101306522 101306688 0.001969641 24.75238095 Hyper-methylatedPCa|NT DMRs chr15 101434708 101442803 0.00358897  −37.5415873Hypo-methylated PCa|NT DMRs chr15 101703020 101703297 0.001969641−31.13492063 Hypo-methylated PCa|NT DMRs chr15 101715537 1017157980.000205174 50.61607143 Hyper-methylated PCa|NT DMRs chr15 101729380101729709 0.000481535 −47.57777778 Hypo-methylated PCa|NT DMRs chr15101807224 101816797 0.002313796 −24.37678571 Hypo-methylated PCa|NT DMRschr15 101938428 101938823 1.76E−06 −52.53174603 Hypo-methylated PCa|NTDMRs chr16 129587 129718 0.000205174 24.92857143 Hyper-methylated PCa|NTDMRs chr16 316409 318893 1.02E−05 −37.50331263 Hypo-methylated PCa|NTDMRs chr16 374770 375243 9.58E−07 52.56491228 Hyper-methylated PCa|NTDMRs chr16 377411 377654 0.001181579 −21.68027211 Hypo-methylated PCa|NTDMRs chr16 390151 390199 0.005968871 42.69142857 Hyper-methylated PCa|NTDMRs chr16 419880 420151 0.003314163 −33.37428571 Hypo-methylated PCa|NTDMRs chr16 452296 452626 0.006589535 −38.58571429 Hypo-methylated PCa|NTDMRs chr16 507998 508061 0.004095673 21.70634921 Hyper-methylated PCa|NTDMRs chr16 521358 521474 0.001969641 44.68650794 Hyper-methylated PCa|NTDMRs chr16 579442 584276 4.08E−09 −24.02521008 Hypo-methylated PCa|NTDMRs chr16 596832 597005 2.31E−05 29.81758242 Hyper-methylated PCa|NTDMRs chr16 607930 608330 0.00179283  44.71130952 Hyper-methylated PCa|NTDMRs chr16 640733 640960 0.005513661 −28.38154762 Hypo-methylated PCa|NTDMRs chr16 648872 651537 5.76E−05 −31.77063492 Hypo-methylated PCa|NTDMRs chr16 666321 667486 0.000205174 −45.48214286 Hypo-methylated PCa|NTDMRs chr16 695119 698338 1.21E−06 −23.22914863 Hypo-methylated PCa|NTDMRs chr16 731089 733945 6.61E−06 −22.893912 Hypo-methylated PCa|NT DMRschr16 771702 772690 7.76E−07 20.40168971 Hyper-methylated PCa|NT DMRschr16 800340 801597 8.84E−07 −41.60869565 Hypo-methylated PCa|NT DMRschr16 804931 805156 0.005542011 26.03463203 Hyper-methylated PCa|NT DMRschr16 809405 809722 4.62E−05 −35.01904762 Hypo-methylated PCa|NT DMRschr16 824130 824399 0.000118733 −39.66031746 Hypo-methylated PCa|NT DMRschr16 831290 831600 0.000822388 30.80519481 Hyper-methylated PCa|NT DMRschr16 833232 834438 0.00016113  −37.3397619 Hypo-methylated PCa|NT DMRschr16 845365 846078 1.82E−06 −44.38644689 Hypo-methylated PCa|NT DMRschr16 879975 880371 0.007433023 25.80753968 Hyper-methylated PCa|NT DMRschr16 881016 881348 1.82E−06 43.82783883 Hyper-methylated PCa|NT DMRschr16 881738 883205 0.004173168 −24.24126984 Hypo-methylated PCa|NT DMRschr16 1017270 1017506 6.69E−05 −23.56785714 Hypo-methylated PCa|NT DMRschr16 1027225 1027604 0.001241245 −30.63186813 Hypo-methylated PCa|NTDMRs chr16 1032361 1032730 3.60E−06 21.51498599 Hyper-methylated PCa|NTDMRs chr16 1054132 1054494 0.00064571  52.65646259 Hyper-methylatedPCa|NT DMRs chr16 1116428 1119025 4.23E−06 −26.82653061 Hypo-methylatedPCa|NT DMRs chr16 1128026 1129023 1.42E−10 −41.94964286 Hypo-methylatedPCa|NT DMRs chr16 1138649 1140099 0.001975042 −28.11002506Hypo-methylated PCa|NT DMRs chr16 1143516 1144910 9.64E−13 30.60883257Hyper-methylated PCa|NT DMRs chr16 1147838 1148922 0.002185514−25.15674603 Hypo-methylated PCa|NT DMRs chr16 1150350 1152475 1.25E−05−25.52354497 Hypo-methylated PCa|NT DMRs chr16 1167634 11680500.00064571  −28.22789116 Hypo-methylated PCa|NT DMRs chr16 12098111210944 6.15E−17 −40.77067271 Hypo-methylated PCa|NT DMRs chr16 12134531213857 0.000491935 26.35 Hyper-methylated PCa|NT DMRs chr16 12387671238824 0.001969641 29.04761905 Hyper-methylated PCa|NT DMRs chr161294104 1295456 5.68E−08 28.52904762 Hyper-methylated PCa|NT DMRs chr161296216 1297328 0.001789867 −31.01904762 Hypo-methylated PCa|NT DMRschr16 1312250 1312413 0.001850915 −22.75 Hypo-methylated PCa|NT DMRschr16 1332687 1333610 9.81E−06 32.34391534 Hyper-methylated PCa|NT DMRschr16 1338204 1338392 0.006410012 −31.67857143 Hypo-methylated PCa|NTDMRs chr16 1339750 1340288 0.000215808 39.78941799 Hyper-methylatedPCa|NT DMRs chr16 1368728 1374052 0.000261046 −23.57653061Hypo-methylated PCa|NT DMRs chr16 1382482 1383057 4.56E−08 31.74450549Hyper-methylated PCa|NT DMRs chr16 1400730 1401063 0.000494377−20.5085034 Hypo-methylated PCa|NT DMRs chr16 1416974 1418827 1.59E−06−42.14744898 Hypo-methylated PCa|NT DMRs chr16 1477905 14787460.000339079 29.43596059 Hyper-methylated PCa|NT DMRs chr16 14806571481065 1.16E−05 −24.0244898 Hypo-methylated PCa|NT DMRs chr16 15107071510800 0.001139334 −26.43650794 Hypo-methylated PCa|NT DMRs chr161544069 1545020 0.0009659  −27.6046176 Hypo-methylated PCa|NT DMRs chr161606297 1606481 0.001969641 −46.36507937 Hypo-methylated PCa|NT DMRschr16 1729914 1730328 2.85E−05 −55.95604396 Hypo-methylated PCa|NT DMRschr16 1737392 1748877 2.28E−05 −29.48150183 Hypo-methylated PCa|NT DMRschr16 1762445 1763089 0.000331541 20.81255411 Hyper-methylated PCa|NTDMRs chr16 1829686 1831723 1.72E−05 −28.79231951 Hypo-methylated PCa|NTDMRs chr16 1843515 1844184 7.47E−06 −32.26031746 Hypo-methylated PCa|NTDMRs chr16 1963218 1963688 0.009503366 −29.73214286 Hypo-methylatedPCa|NT DMRs chr16 1988972 1989208 0.001969641 30.27539683Hyper-methylated PCa|NT DMRs chr16 2013337 2013474 0.005968871−33.3247619 Hypo-methylated PCa|NT DMRs chr16 2040902 2041613 6.80E−0927.18174603 Hyper-methylated PCa|NT DMRs chr16 2042480 2042875 1.74E−0825.47312169 Hyper-methylated PCa|NT DMRs chr16 2077489 20797110.000457787 −22.55531136 Hypo-methylated PCa|NT DMRs chr16 20829852083178 0.007560755 22.00416667 Hyper-methylated PCa|NT DMRs chr162083393 2083684 6.42E−05 21.6031746 Hyper-methylated PCa|NT DMRs chr162094109 2094645 0.004095673 45.76984127 Hyper-methylated PCa|NT DMRschr16 2139882 2141984 2.25E−12 −33.41763192 Hypo-methylated PCa|NT DMRschr16 2173124 2176198 2.74E−08 26.98794326 Hyper-methylated PCa|NT DMRschr16 2212733 2213016 1.42E−05 −25.8707483 Hypo-methylated PCa|NT DMRschr16 2261316 2264037 0.001337734 −24.2162465 Hypo-methylated PCa|NTDMRs chr16 2286538 2288301 1.97E−17 26.84145658 Hyper-methylated PCa|NTDMRs chr16 2310317 2315610 0.000836132 −44.47619048 Hypo-methylatedPCa|NT DMRs chr16 2319266 2319666 0.009807302 −24.76904762Hypo-methylated PCa|NT DMRs chr16 2323514 2323894 8.96E−05 −48.93253968Hypo-methylated PCa|NT DMRs chr16 2391323 2392106 9.81E−13 26.07663004Hyper-methylated PCa|NT DMRs chr16 2531115 2531267 0.001969641−43.38650794 Hypo-methylated PCa|NT DMRs chr16 2536085 2537560 6.69E−0538.79047619 Hyper-methylated PCa|NT DMRs chr16 2556878 25574980.006589535 38.23285714 Hyper-methylated PCa|NT DMRs chr16 25599032563541 0.00641359  24.86507937 Hyper-methylated PCa|NT DMRs chr162569458 2569997 0.003162339 −33.55238095 Hypo-methylated PCa|NT DMRschr16 2579575 2579747 0.000339757 −24.28571429 Hypo-methylated PCa|NTDMRs chr16 2587001 2587382 0.001789867 −32.88253968 Hypo-methylatedPCa|NT DMRs chr16 2731606 2731884 0.003583021 −28.56428571Hypo-methylated PCa|NT DMRs chr16 2740098 2740473 0.00146640241.04285714 Hyper-methylated PCa|NT DMRs chr16 2753295 2753532 6.42E−05−52.0952381 Hypo-methylated PCa|NT DMRs chr16 2767656 27680220.002585277 30.85119048 Hyper-methylated PCa|NT DMRs chr16 27707842770842 0.007573168 22.00340136 Hyper-methylated PCa|NT DMRs chr162774824 2775168 0.007560755 −22.30952381 Hypo-methylated PCa|NT DMRschr16 3002543 3003018 0.002437742 −41.31216931 Hypo-methylated PCa|NTDMRs chrl6 3008659 3010399 0.005578507 −35.06227106 Hypo-methylatedPCa|NT DMRs chr16 3096651 3105181 1.92E−08 26.14668737 Hyper-methylatedPCa|NT DMRs chr16 3142132 3143251 1.24E−05 −35.07563025 Hypo-methylatedPCa|NT DMRs chr16 3221699 3222366 5.01E−08 21.03040293 Hyper-methylatedPCa|NT DMRs chr16 3230711 3230853 0.002373155 20.19047619Hyper-methylated PCa|NT DMRs chr16 3237212 3238613 8.38E−05 20.60451128Hyper-methylated PCa|NT DMRs chr16 3245574 3257521 0.00179283 −30.85059524 Hypo-methylated PCa|NT DMRs chr16 3345159 33454150.000122527 21.06971429 Hyper-methylated PCa|NT DMRs chr16 34006583406974 5.20E−08 −21.15363409 Hypo-methylated PCa|NT DMRs chr16 35500663550247 4.16E−07 34.70327381 Hyper-methylated PCa|NT DMRs chr16 36255613630897 7.45E−05 29.80431548 Hyper-methylated PCa|NT DMRs chr16 36390223641715 1.60E−07 28.85714286 Hyper-methylated PCa|NT DMRs chr16 36955923696467 0.000783791 −37.92857143 Hypo-methylated PCa|NT DMRs chr163746410 3746889 0.00064571  −52.8877551 Hypo-methylated PCa|NT DMRschr16 3770441 3774701 0.001171318 −20.73917749 Hypo-methylated PCa|NTDMRs chr16 3999452 4004641 4.41E−05 34.07006803 Hyper-methylated PCa|NTDMRs chr16 4008010 4008280 0.006743251 −27.22433862 Hypo-methylatedPCa|NT DMRs chr16 4366670 4368899 0.001022616 −24.48138528Hypo-methylated PCa|NT DMRs chr16 4452456 4453668 0.006518597−30.84081633 Hypo-methylated PCa|NT DMRs chr16 4464451 44657630.009106413 45.51269841 Hyper-methylated PCa|NT DMRs chr16 45876194588433 3.15E−11 24.92796353 Hyper-methylated PCa|NT DMRs chr16 46861974687202 0.000200126 30.66849817 Hyper-methylated PCa|NT DMRs chr164710700 4717443 3.61E−06 32.68673469 Hyper-methylated PCa|NT DMRs chr164723493 4723653 0.000190021 −25.71428571 Hypo-methylated PCa|NT DMRschr16 4739859 4741376 0.000103014 25.95658263 Hyper-methylated PCa|NTDMRs chr16 4851034 4851345 0.003464153 20.3333333 Hyper-methylatedPCa|NT DMRs chr16 4854036 4864547 0.000210841 −28.4952381Hypo-methylated PCa|NT DMRs chr16 5030424 5038314 2.93E−05 30.95714286Hyper-methylated PCa|NT DMRs chr16 5298577 5537115 3.20E−13 −34.68508403Hypo-methylated PCa|NT DMRs chr16 5571821 6049568 2.15E−29 −35.58996728Hypo-methylated PCa|NT DMRs chr16 6049600 6056311 0.004553481−32.63544974 Hypo-methylated PCa|NT DMRs chr16 6093876 6523101 4.85E−27−34.88836996 Hypo-methylated PCa|NT DMRs chr16 6695394 6771171 1.59E−11−31.27422969 Hypo-methylated PCa|NT DMRs chr16 6865061 7338727 3.17E−31−34.86954436 Hypo-methylated PCa|NT DMRs chr16 7359520 7694298 2.47E−17−37.27677656 Hypo-methylated PCa|NT DMRs chr16 7710748 8148995 1.28E−14−38.47738095 Hypo-methylated PCa|NT DMRs chr16 8158434 8609206 1.19E−31−35.50872314 Hypo-methylated PCa|NT DMRs chr16 8779964 87800630.005968871 −53.99428571 Hypo-methylated PCa|NT DMRs chr16 88087108815433 0.000118733 −39.26455026 Hypo-methylated PCa|NT DMRs chr168960174 8960904 4.11E−07 −54.43007519 Hypo-methylated PCa|NT DMRs chr168963552 8963808 1.34E−05 31.58843537 Hyper-methylated PCa|NT DMRs chr169107009 9107319 2.81E−09 42.40384615 Hyper-methylated PCa|NT DMRs chr169184207 9184407 8.69E−05 22.28163265 Hyper-methylated PCa|NT DMRs chr169248446 9250894 0.003034084 22.55782313 Hyper-methylated PCa|NT DMRschr16 9283984 9335815 9.05E−09 −34.52765568 Hypo-methylated PCa|NT DMRschr16 10481704 10482044 0.000117699 −34.77922078 Hypo-methylated PCa|NTDMRs chr16 10652798 10653288 0.000974795 −63.29761905 Hypo-methylatedPCa|NT DMRs chr16 10716275 10721971 0.00641359  −21.97619048Hypo-methylated PCa|NT DMRs chr16 10912139 10912855 2.06E−07 29.61612903Hyper-methylated PCa|NT DMRs chr16 10912902 10935122 0.000493372−23.57431078 Hypo-methylated PCa|NT DMRs chr16 10968136 109722980.000847246 45.44322344 Hyper-methylated PCa|NT DMRs chr16 1097351110974993 0.005498599 31.77769424 Hyper-methylated PCa|NT DMRs chr1610985729 10985903 0.000205174 41.43154762 Hyper-methylated PCa|NT DMRschr16 11227260 11227346 0.000205174 −39.53571429 Hypo-methylated PCa|NTDMRs chr16 11282987 11283381 6.42E−05 −49.04761905 Hypo-methylatedPCa|NT DMRs chr16 11304969 11305220 0.00179283  −24.47916667Hypo-methylated PCa|NT DMRs chr16 11480649 11481343 0.00142861520.98958333 Hyper-methylated PCa|NT DMRs chr16 11485462 114859230.001969641 −49.46428571 Hypo-methylated PCa|NT DMRs chr16 1151903711524271 7.48E−05 27.47804233 Hyper-methylated PCa|NT DMRs chr1611763088 11764208 0.000814525 25.01888342 Hyper-methylated PCa|NT DMRschr16 11893815 11893874 0.005968871 50.65714286 Hyper-methylated PCa|NTDMRs chr16 12010419 12010699 6.42E−05 −43.13492063 Hypo-methylatedPCa|NT DMRs chr16 12352125 12352377 0.001181579 −41.44557823Hypo-methylated PCa|NT DMRs chr16 12355015 12355349 1.69E−06−23.46722689 Hypo-methylated PCa|NT DMRs chr16 12992665 129945960.000117699 21.57968254 Hyper-methylated PCa|NT DMRs chr16 1352437513545035 1.76E−06 −20.1218254 Hypo-methylated PCa|NT DMRs chr16 1374188613904843 2.62E−05 −24.95995671 Hypo-methylated PCa|NT DMRs chr1614397001 14397993 7.93E−05 28.99180952 Hyper-methylated PCa|NT DMRschr16 15797238 15797298 0.005968871 26.68571429 Hyper-methylated PCa|NTDMRs chr16 15952405 15952484 5.84E−05 24.5952381 Hyper-methylated PCa|NTDMRs chr16 16116243 16122627 0.000972067 −35.01322751 Hypo-methylatedPCa|NT DMRs chr16 16693301 16730538 1.16E−07 −27.47142857Hypo-methylated PCa|NT DMRs chr16 17107610 17107826 0.00196964123.53968254 Hyper-methylated PCa|NT DMRs chr16 17199250 172002440.006096657 20.26587302 Hyper-methylated PCa|NT DMRs chr16 1736053217360585 0.00064571  −49.53061224 Hypo-methylated PCa|NT DMRs chr1617699253 17813072 2.33E−10 −30.3315873 Hypo-methylated PCa|NT DMRs chr1619030300 19041334 0.007959104 −33.31292517 Hypo-methylated PCa|NT DMRschr16 19088006 19088442 0.003448944 −41.3877551 Hypo-methylated PCa|NTDMRs chr16 19125846 19126157 5.27E−08 24.08823529 Hyper-methylatedPCa|NT DMRs chr16 19147105 19150057 0.007391799 −28.62380952Hypo-methylated PCa|NT DMRs chr16 19568951 19570034 0.003622801−25.61904762 Hypo-methylated PCa|NT DMRs chr16 19894307 198955795.30E−12 23.46248548 Hyper-methylated PCa|NT DMRs chr16 1989701319897156 0.001451132 21.08051948 Hyper-methylated PCa|NT DMRs chr1620397851 20398315 0.00324187  25.94217687 Hyper-methylated PCa|NT DMRschr16 20923684 20923750 0.003448944 23.53061224 Hyper-methylated PCa|NTDMRs chr16 21294947 21295120 0.000233379 36.38571429 Hyper-methylatedPCa|NT DMRs chr16 21656698 21658713 0.000260936 23.8 Hyper-methylatedPCa|NT DMRs chr16 22635683 22675597 0.005646573 −28.15068027Hypo-methylated PCa|NT DMRs chr16 22745523 22745899 0.000117699−47.20952381 Hypo-methylated PCa|NT DMRs chr16 23706211 237065381.68E−05 22.70982143 Hyper-methylated PCa|NT DMRs chr16 2385011424266921 3.40E−18 −36.39916944 Hypo-methylated PCa|NT DMRs chr1625704220 25704401 1.17E−08 29.75496032 Hyper-methylated PCa|NT DMRschr16 26676580 26700624 0.000286238 −32.4014652 Hypo-methylated PCa|NTDMRs chr16 27231985 27234625 0.001083007 −40.84285714 Hypo-methylatedPCa|NT DMRs chr16 27237991 27238100 6.42E−05 −33.22539683Hypo-methylated PCa|NT DMRs chr16 27243976 27244604 5.94E−06−41.46493506 Hypo-methylated PCa|NT DMRs chr16 27325893 273273150.003871035 25.43452381 Hyper-methylated PCa|NT DMRs chr16 2733009727330246 0.00064571  59.93197279 Hyper-methylated PCa|NT DMRs chr1627445366 27445781 0.005674668 −31.94557823 Hypo-methylated PCa|NT DMRschr16 27475091 27475140 0.008234951 23.36 Hyper-methylated PCa|NT DMRschr16 27510503 27511270 0.000514174 −31.33766234 Hypo-methylated PCa|NTDMRs chr16 27791162 27791356 4.08E−06 −25.5327381 Hypo-methylated PCa|NTDMRs chr16 27792769 27793304 0.00068166  −44.05357143 Hypo-methylatedPCa|NT DMRs chr16 27984243 28014977 0.004691973 −22.82993197Hypo-methylated PCa|NT DMRs chr16 28312542 28321579 0.00253492828.41428571 Hyper-methylated PCa|NT DMRs chr16 28505826 285061180.005968871 50.5952381 Hyper-methylated PCa|NT DMRs chr16 2854926728550794 5.19E−07 −59.83113553 Hypo-methylated PCa|NT DMRs chr1628555134 28564807 0.003448944 −32.83265306 Hypo-methylated PCa|NT DMRschr16 28750459 28758726 0.000339627 21.16309524 Hyper-methylated PCa|NTDMRs chr16 28893790 28894485 4.11E−06 −34.03063492 Hypo-methylatedPCa|NT DMRs chr16 28914467 28914660 0.004095673 38.69206349Hyper-methylated PCa|NT DMRs chr16 28995537 28999703 5.37E−0546.23952381 Hyper-methylated PCa|NT DMRs chr16 29030346 290317140.000205174 −21.32440476 Hypo-methylated PCa|NT DMRs chr16 2908622129086283 0.00023371  45.45714286 Hyper-methylated PCa|NT DMRs chr1629118855 29118998 0.002373155 −39.82539683 Hypo-methylated PCa|NT DMRschr16 29140241 29159108 2.15E−11 −25.04742468 Hypo-methylated PCa|NTDMRs chr16 29160196 29160273 0.00064571  39.69387755 Hyper-methylatedPCa|NT DMRs chr16 29170156 29189484 4.92E−13 −25.3822619 Hypo-methylatedPCa|NT DMRs chr16 29191465 29193962 4.20E−07 −22.00910973Hypo-methylated PCa|NT DMRs chr16 29229209 29268470 8.33E−29−23.31564073 Hypo-methylated PCa|NT DMRs chr16 29697695 297011160.004553481 34.11904762 Hyper-methylated PCa|NT DMRs chr16 2975550329758784 1.96E−05 27.1875 Hyper-methylated PCa|NT DMRs chr16 2983088729831040 2.06E−05 −33.41836735 Hypo-methylated PCa|NT DMRs chr1629868727 29870508 0.000483473 −20.96390977 Hypo-methylated PCa|NT DMRschr16 29887710 29890333 3.49E−12 36.93904762 Hyper-methylated PCa|NTDMRs chr16 30034006 30036062 0.000836132 −27.81746032 Hypo-methylatedPCa|NT DMRs chr16 30066508 30066606 0.001969641 37.97619048Hyper-methylated PCa|NT DMRs chr16 30103997 30104150 0.00111530225.69642857 Hyper-methylated PCa|NT DMRs chr16 30370636 303751831.42E−05 −20.76857143 Hypo-methylated PCa|NT DMRs chr16 3048505330485425 3.61E−05 38.51870748 Hyper-methylated PCa|NT DMRs chr1630567234 30567586 0.001344447 −39.85873016 Hypo-methylated PCa|NT DMRschr16 30572702 30573334 2.01E−09 22.61778976 Hyper-methylated PCa|NTDMRs chr16 30660787 30661577 0.002437742 35.36772487 Hyper-methylatedPCa|NT DMRs chr16 30736144 30736666 8.96E−05 25.78061224Hyper-methylated PCa|NT DMRs chr16 30907606 30908535 2.17E−1023.55592186 Hyper-methylated PCa|NT DMRs chr16 30914154 309158890.004553481 34.89417989 Hyper-methylated PCa|NT DMRs chr16 3097618730976274 0.005968871 37.92 Hyper-methylated PCa|NT DMRs chr16 3100439831004456 0.003871035 32.125 Hyper-methylated PCa|NT DMRs chr16 3101328931020068 0.002193447 −23.295671 Hypo-methylated PCa|NT DMRs chr1631075643 31075742 0.000652677 48.67222222 Hyper-methylated PCa|NT DMRschr16 31120626 31120674 0.003871035 −24.89285714 Hypo-methylated PCa|NTDMRs chr16 31141563 31141817 0.001115302 23.19642857 Hyper-methylatedPCa|NT DMRs chr16 31226074 31226186 0.00023371  27.26666667Hyper-methylated PCa|NT DMRs chr16 31271642 31271992 0.00196964138.81984127 Hyper-methylated PCa|NT DMRs chr16 31276614 312768380.00641359  20.54761905 Hyper-methylated PCa|NT DMRs chr16 3128296931341899 8.62E−12 −24.68791756 Hypo-methylated PCa|NT DMRs chr1631363703 31363807 0.003622801 28.94761905 Hyper-methylated PCa|NT DMRschr16 31368394 31368868 0.009924186 20.1952381 Hyper-methylated PCa|NTDMRs chr16 31548681 31549142 5.49E−13 22.38095238 Hyper-methylatedPCa|NT DMRs chr16 31590383 31709112 4.30E−08 −31.54642857Hypo-methylated PCa|NT DMRs chr16 32297137 32300810 0.000117699−29.54588745 Hypo-methylated PCa|NT DMRs chr16 32338210 323525200.002048317 −27.125 Hypo-methylated PCa|NT DMRs chr16 32640501 326457980.00379014  −34.72916667 Hypo-methylated PCa|NT DMRs chr16 3323796233298210 1.21E−06 −27.73581781 Hypo-methylated PCa|NT DMRs chr1633406088 33483659 2.02E−09 −30.97863578 Hypo-methylated PCa|NT DMRschr16 33944442 33949690 1.62E−05 −22.26060606 Hypo-methylated PCa|NTDMRs chr16 33955811 33956699 0.005968871 −23.84415584 Hypo-methylatedPCa|NT DMRs chr16 33958841 33959929 0.000232782 −25.0702381Hypo-methylated PCa|NT DMRs chr16 46765374 46765466 0.008482405−53.82285714 Hypo-methylated PCa|NT DMRs chr16 46791236 467914940.001969641 −46.7755102 Hypo-methylated PCa|NT DMRs chr16 4687831446878490 7.15E−06 27.615 Hyper-methylated PCa|NT DMRs chr16 4691900446921305 0.003535943 −20.41552028 Hypo-methylated PCa|NT DMRs chr1646945625 46956365 1.20E−05 −46.18095238 Hypo-methylated PCa|NT DMRschr16 48093524 48094446 2.41E−08 −29.40062112 Hypo-methylated PCa|NTDMRs chr16 48641898 48643082 0.001237229 −27.32261905 Hypo-methylatedPCa|NT DMRs chr16 48644653 48644724 0.005513661 −20.06845238Hypo-methylated PCa|NT DMRs chr16 48663320 48663544 0.000215808−39.88095238 Hypo-methylated PCa|NT DMRs chr16 48665375 487338110.001241245 −34.85873016 Hypo-methylated PCa|NT DMRs chr16 4952529549525795 0.001563885 −30.705 Hypo-methylated PCa|NT DMRs chr16 4953720749537395 0.001969641 37.54761905 Hyper-methylated PCa|NT DMRs chr1649758531 49764953 1.44E−06 −25.93109244 Hypo-methylated PCa|NT DMRschr16 49776723 49800714 0.00046742  −23.87662338 Hypo-methylated PCa|NTDMRs chr16 49911050 49930277 0.001993134 −20.01515152 Hypo-methylatedPCa|NT DMRs chr16 50280386 50280724 0.00068008  28.49548872Hyper-methylated PCa|NT DMRs chr16 50301976 50318037 1.45E−0742.65498866 Hyper-methylated PCa|NT DMRs chr16 50715181 507203560.001139334 36.15079365 Hyper-methylated PCa|NT DMRs chr16 5087516650875609 4.35E−06 20.3987013 Hyper-methylated PCa|NT DMRs chr16 5146750751591255 7.09E−05 −25.65057471 Hypo-methylated PCa|NT DMRs chr1652581377 52589163 2.42E−06 31.60547619 Hyper-methylated PCa|NT DMRschr16 52655635 52655804 0.001969641 −34.19206349 Hypo-methylated PCa|NTDMRs chr16 54209645 54210071 0.00064571  20.82312925 Hyper-methylatedPCa|NT DMRs chr16 54268993 54269138 0.005968871 40.48571429Hyper-methylated PCa|NT DMRs chr16 54465950 54467538 8.94E−0531.65162907 Hyper-methylated PCa|NT DMRs chr16 54851427 548517270.007347803 −24.80952381 Hypo-methylated PCa|NT DMRs chr16 5504080955079401 1.54E−12 −23.83809524 Hypo-methylated PCa|NT DMRs chr1655290536 55297451 2.42E−08 −32.2672619 Hypo-methylated PCa|NT DMRs chr1655425192 55504853 3.58E−07 −31.55192744 Hypo-methylated PCa|NT DMRschr16 55519607 55522628 0.000205174 −24.08333333 Hypo-methylated PCa|NTDMRs chr16 56362672 56362957 5.71E−06 −20.22321429 Hypo-methylatedPCa|NT DMRs chr16 56385026 56386186 0.001969641 −20.17460317Hypo-methylated PCa|NT DMRs chr16 56661082 56661690 0.005513661−43.98027211 Hypo-methylated PCa|NT DMRs chr16 56668846 566738681.03E−24 34.13711002 Hyper-methylated PCa|NT DMRs chr16 5668170356682206 2.49E−05 23.73764881 Hyper-methylated PCa|NT DMRs chr1656696592 56697034 3.11E−06 33.57261905 Hyper-methylated PCa|NT DMRschr16 56703388 56704438 1.73E−10 31.3697995 Hyper-methylated PCa|NT DMRschr16 56709403 56715456 0.000143323 26.59255189 Hyper-methylated PCa|NTDMRs chr16 56892413 56892547 6.93E−06 52.45714286 Hyper-methylatedPCa|NT DMRs chr16 57311903 57318285 0.001651534 20.79831029Hyper-methylated PCa|NT DMRs chr16 57352141 57373846 0.007959104−35.28911565 Hypo-methylated PCa|NT DMRs chr16 57509003 575100040.000122432 35.05194805 Hyper-methylated PCa|NT DMRs chr16 5751294057513297 2.87E−06 30.00661376 Hyper-methylated PCa|NT DMRs chr1657519833 57520015 2.85E−05 27.35714286 Hyper-methylated PCa|NT DMRschr16 57578985 57605309 0.00023371  −27.97190476 Hypo-methylated PCa|NTDMRs chr16 57648940 57657248 1.34E−08 −39.91803752 Hypo-methylatedPCa|NT DMRs chr16 57659254 57659440 0.001969641 52.95634921Hyper-methylated PCa|NT DMRs chr16 57662166 57697216 2.15E−0629.26357143 Hyper-methylated PCa|NT DMRs chr16 57828807 578322925.71E−10 −35.82578397 Hypo-methylated PCa|NT DMRs chr16 5801844058018757 8.75E−05 24.15079365 Hyper-methylated PCa|NT DMRs chr1658115573 58115754 0.004095673 40.5952381 Hyper-methylated PCa|NT DMRschr16 58148917 58149526 0.000570576 −24.34920635 Hypo-methylated PCa|NTDMRs chr16 58880322 59494155 2.60E−19 −34.49847375 Hypo-methylatedPCa|NT DMRs chr16 59554848 59788978 3.75E−12 −30.41439909Hypo-methylated PCa|NT DMRs chr16 62485889 62682151 2.01E−07−36.32928571 Hypo-methylated PCa|NT DMRs chr16 62758889 629928233.46E−15 −28.91492674 Hypo-methylated PCa|NT DMRs chr16 6636070466361203 1.76E−06 −47.7218254 Hypo-methylated PCa|NT DMRs chr16 6643662466437053 7.33E−10 −21.65894466 Hypo-methylated PCa|NT DMRs chr1666461441 66462196 9.31E−10 22.17904762 Hyper-methylated PCa|NT DMRschr16 66969363 66969606 2.18E−06 −36.13784461 Hypo-methylated PCa|NTDMRs chr16 66982435 66982944 5.37E−09 33.00549451 Hyper-methylatedPCa|NT DMRs chr16 67184052 67188775 4.76E−17 23.42979094Hyper-methylated PCa|NT DMRs chr16 67195270 67196089 0.003764982−23.73809524 Hypo-methylated PCa|NT DMRs chr16 67196900 672045092.41E−28 31.29674185 Hyper-methylated PCa|NT DMRs chr16 6720880067209081 0.001969641 20.58095238 Hyper-methylated PCa|NT DMRs chr1667226937 67234153 1.09E−16 −38.08596491 Hypo-methylated PCa|NT DMRschr16 67241436 67241710 0.000205174 −51.98214286 Hypo-methylated PCa|NTDMRs chr16 67318599 67319292 0.000564835 −36.59340659 Hypo-methylatedPCa|NT DMRs chr16 67335510 67335792 0.00064571  −50.74829932Hypo-methylated PCa|NT DMRs chr16 67427105 67429065 1.41E−23 28.25015576Hyper-methylated PCa|NT DMRs chr16 67475109 67481530 0.000580099−35.4929972 Hypo-methylated PCa|NT DMRs chr16 67552676 675528350.005968871 51.5952381 Hyper-methylated PCa|NT DMRs chr16 6767810267679557 4.59E−10 20.634 Hyper-methylated PCa|NT DMRs chr16 6768206567688497 5.32E−23 −33.09000249 Hypo-methylated PCa|NT DMRs chr1667701162 67703106 0.001391421 28.17662338 Hyper-methylated PCa|NT DMRschr16 67916426 67918902 1.56E−05 −43.96492063 Hypo-methylated PCa|NTDMRs chr16 67960491 67960722 0.000377317 −35.28571429 Hypo-methylatedPCa|NT DMRs chr16 67967146 67969343 0.001083007 −42.13142857Hypo-methylated PCa|NT DMRs chr16 68001760 68002208 1.34E−05 24.76693122Hyper-methylated PCa|NT DMRs chr16 68035220 68053960 6.69E−05−26.6047619 Hypo-methylated PCa|NT DMRs chr16 68109138 68119017 1.09E−0736.05064935 Hyper-methylated PCa|NT DMRs chr16 68265576 682710468.06E−08 −22.62292627 Hypo-methylated PCa|NT DMRs chr16 6838526968385717 5.84E−05 −39.30555556 Hypo-methylated PCa|NT DMRs chr1668389417 68390717 4.25E−06 40.31878307 Hyper-methylated PCa|NT DMRschr16 68411847 68412150 0.00641359  −34.96428571 Hypo-methylated PCa|NTDMRs chr16 68670007 68670380 0.000205174 −52.42261905 Hypo-methylatedPCa|NT DMRs chr16 68676215 68678616 3.89E−23 37.88924162Hyper-methylated PCa|NT DMRs chr16 69141067 69142170 4.52E−1427.99831933 Hyper-methylated PCa|NT DMRs chr16 69895355 698960370.007959104 −37.65646259 Hypo-methylated PCa|NT DMRs chr16 6997142269971565 0.001583444 −21.31428571 Hypo-methylated PCa|NT DMRs chr1670222533 70222612 0.000474737 29.1962963 Hyper-methylated PCa|NT DMRschr16 70321963 70322213 0.000205174 −44.46130952 Hypo-methylated PCa|NTDMRs chr16 70381845 70381893 0.005968871 −26.82857143 Hypo-methylatedPCa|NT DMRs chr16 70457082 70460575 0.005674668 31.61020408Hyper-methylated PCa|NT DMRs chr16 70633352 70642101 0.002767976−23.35714286 Hypo-methylated PCa|NT DMRs chr16 70646782 706474160.003689112 33.99267399 Hyper-methylated PCa|NT DMRs chr16 7140745871414373 6.69E−05 −22.52571429 Hypo-methylated PCa|NT DMRs chr1671465153 71467260 0.003871035 −30.39285714 Hypo-methylated PCa|NT DMRschr16 71844062 71845892 0.002767976 26.05800866 Hyper-methylated PCa|NTDMRs chr16 72661210 72661480 0.00023371  −35.65714286 Hypo-methylatedPCa|NT DMRs chr16 72940258 72940306 0.001969641 23.39285714Hyper-methylated PCa|NT DMRs chr16 73461766 73514946 6.85E−06−25.06582633 Hypo-methylated PCa|NT DMRs chr16 73716406 737164500.005968871 −21.05238095 Hypo-methylated PCa|NT DMRs chr16 7390035773900614 0.005968871 −45.20380952 Hypo-methylated PCa|NT DMRs chr1674030719 74064139 0.000205174 −25.10714286 Hypo-methylated PCa|NT DMRschr16 74411948 74433121 0.002826041 −26.2755102 Hypo-methylated PCa|NTDMRs chr16 74777837 74778058 0.001969641 −64.62517007 Hypo-methylatedPCa|NT DMRs chr16 75256329 75261099 0.000438659 −28.59761905Hypo-methylated PCa|NT DMRs chr16 75279396 75282362 0.003391914−29.32592593 Hypo-methylated PCa|NT DMRs chr16 75540559 755407080.005968871 25.42857143 Hyper-methylated PCa|NT DMRs chr16 7722864877228980 5.84E−05 −29.325 Hypo-methylated PCa|NT DMRs chr16 7736970477392244 2.79E−05 −27.3047619 Hypo-methylated PCa|NT DMRs chr16 7789586277918602 0.00179283  −25.95454545 Hypo-methylated PCa|NT DMRs chr1679253101 79287222 0.001060348 −23.83982684 Hypo-methylated PCa|NT DMRschr16 79463826 79464272 0.00064571  −41.01496599 Hypo-methylated PCa|NTDMRs chr16 79553532 79553817 0.001076343 33.49350649 Hyper-methylatedPCa|NT DMRs chr16 81270959 81272783 0.005968871 −60.49142857Hypo-methylated PCa|NT DMRs chr16 81434752 81435017 0.000205174−54.74642857 Hypo-methylated PCa|NT DMRs chr16 81490286 815069990.00641359  20.28698413 Hyper-methylated PCa|NT DMRs chr16 8152819481529074 0.000117699 44.24935065 Hyper-methylated PCa|NT DMRs chr1681552099 81554825 0.001111028 20.4042328 Hyper-methylated PCa|NT DMRschr16 81580631 81585567 0.000783791 21.05238095 Hyper-methylated PCa|NTDMRs chr16 81632836 81640483 0.000754912 −33.94984127 Hypo-methylatedPCa|NT DMRs chr16 81776981 81778849 0.007959104 −24.16122449Hypo-methylated PCa|NT DMRs chr16 81832432 81836220 0.00596887139.90793651 Hyper-methylated PCa|NT DMRs chr16 83442827 834979741.85E−06 −28.03781513 Hypo-methylated PCa|NT DMRs chr16 8365533983728737 4.93E−07 −24.46666667 Hypo-methylated PCa|NT DMRs chr1683914357 83916269 0.000205174 −24.51309524 Hypo-methylated PCa|NT DMRschr16 84057355 84057681 0.000215808 −26.58730159 Hypo-methylated PCa|NTDMRs chr16 84078931 84079123 0.002094   29.6452381 Hyper-methylatedPCa|NT DMRs chr16 84327616 84328392 0.000371883 32.96642857Hyper-methylated PCa|NT DMRs chr16 84335171 84336770 0.000170278−20.21428571 Hypo-methylated PCa|NT DMRs chr16 84390197 843904680.005968871 −50.21428571 Hypo-methylated PCa|NT DMRs chr16 8444171684441780 0.008482405 −51.25714286 Hypo-methylated PCa|NT DMRs chr1684578282 84578376 0.005968871 42.14761905 Hyper-methylated PCa|NT DMRschr16 84763185 84771552 0.006170736 −27.19421769 Hypo-methylated PCa|NTDMRs chr16 84819552 84819620 0.00068166  −29.69642857 Hypo-methylatedPCa|NT DMRs chr16 84860443 84860841 0.001789867 22.75132275Hyper-methylated PCa|NT DMRs chr16 84861455 84861803 3.44E−06−47.92857143 Hypo-methylated PCa|NT DMRs chr16 84876118 848768626.69E−05 −38.13333333 Hypo-methylated PCa|NT DMRs chr16 8491882384919169 0.000205174 40.95178571 Hyper-methylated PCa|NT DMRs chr1684943821 84950077 0.000296718 27.55646259 Hyper-methylated PCa|NT DMRschr16 85110644 85112489 0.00046742  37.60779221 Hyper-methylated PCa|NTDMRs chr16 85116332 85119269 6.51E−07 51.89104762 Hyper-methylatedPCa|NT DMRs chr16 85168443 85170151 6.69E−05 31.93854875Hyper-methylated PCa|NT DMRs chr16 85183518 85183685 0.005968871−56.57142857 Hypo-methylated PCa|NT DMRs chr16 85203608 852039401.69E−06 25.3226601 Hyper-methylated PCa|NT DMRs chr16 85271771 852720630.000294557 22.48484848 Hyper-methylated PCa|NT DMRs chr16 8529269085296087 5.84E−05 48.92420635 Hyper-methylated PCa|NT DMRs chr1685337819 85349956 1.30E−06 32.44621849 Hyper-methylated PCa|NT DMRschr16 85361134 85363063 0.001083007 30.84285714 Hyper-methylated PCa|NTDMRs chr16 85388137 85388729 0.001115302 33.05952381 Hyper-methylatedPCa|NT DMRs chr16 85418540 85418838 0.000652677 −28.44047619Hypo-methylated PCa|NT DMRs chr16 85418881 85422836 0.00186647132.5242236 Hyper-methylated PCa|NT DMRs chr16 85429386 854295700.009106413 27.98412698 Hyper-methylated PCa|NT DMRs chr16 8549544885495725 0.00064571  44.31292517 Hyper-methylated PCa|NT DMRs chr1685517185 85518386 6.42E−05 −33.19047619 Hypo-methylated PCa|NT DMRschr16 85522260 85522512 0.001969641 22.00396825 Hyper-methylated PCa|NTDMRs chr16 85551958 85552154 0.000205174 24.38392857 Hyper-methylatedPCa|NT DMRs chr16 85554650 85557931 2.26E−06 −36.81547619Hypo-methylated PCa|NT DMRs chr16 85600230 85607809 5.84E−06 24.21606134Hyper-methylated PCa|NT DMRs chr16 85619999 85620238 7.57E−05−43.33333333 Hypo-methylated PCa|NT DMRs chr16 85741402 857415551.97E−05 −53.34 Hypo-methylated PCa|NT DMRs chr16 85783538 857841930.00051204  43.96285714 Hyper-methylated PCa|NT DMRs chr16 8581631685816992 0.003871035 34.9797619 Hyper-methylated PCa|NT DMRs chr1685981833 85982028 0.000205174 32.79761905 Hyper-methylated PCa|NT DMRschr16 85982195 86005909 1.70E−06 −27.07301587 Hypo-methylated PCa|NTDMRs chr16 86605190 86607704 5.99E−05 −25.96630037 Hypo-methylatedPCa|NT DMRs chr16 86611303 86611892 0.000215808 −24.44444444Hypo-methylated PCa|NT DMRs chr16 86625460 86629385 4.73E−05 −36.4360119Hypo-methylated PCa|NT DMRs chr16 86962224 86963104 8.82E−07 20.72419562Hyper-methylated PCa|NT DMRs chr16 87086835 87087126 8.28E−0725.81746032 Hyper-methylated PCa|NT DMRs chr16 87312849 873131330.00641359  −21.81746032 Hypo-methylated PCa|NT DMRs chr16 8735857187358621 0.00064571  40.88095238 Hyper-methylated PCa|NT DMRs chr1687417801 87418310 0.000117986 27.59821429 Hyper-methylated PCa|NT DMRschr16 87527371 87531345 9.23E−05 −46.22745098 Hypo-methylated PCa|NTDMRs chr16 87545844 87550120 6.42E−05 −21.22486772 Hypo-methylatedPCa|NT DMRs chr16 87552012 87552511 0.00023371  −24.4965368Hypo-methylated PCa|NT DMRs chr16 87569839 87572637 0.005968871−33.61714286 Hypo-methylated PCa|NT DMRs chr16 87624313 876282483.10E−09 −28.4764411 Hypo-methylated PCa|NT DMRs chr16 87671820 876755385.78E−05 −26.32380952 Hypo-methylated PCa|NT DMRs chr16 8768159687682204 2.82E−10 −26.15873016 Hypo-methylated PCa|NT DMRs chr1687690069 87690138 0.002097193 −33.67346939 Hypo-methylated PCa|NT DMRschr16 87717884 87718134 1.42E−05 −47.05952381 Hypo-methylated PCa|NTDMRs chr16 87720606 87720767 0.007959104 −29.95918367 Hypo-methylatedPCa|NT DMRs chr16 87842167 87843352 0.002097193 37.21972789Hyper-methylated PCa|NT DMRs chr16 87850009 87850371 1.97E−0534.11428571 Hyper-methylated PCa|NT DMRs chr16 87852974 878537101.11E−05 −26.4025974 Hypo-methylated PCa|NT DMRs chr16 87857290 878608841.12E−09 −22.9912892 Hypo-methylated PCa|NT DMRs chr16 87942514 879451593.89E−05 −50.69047619 Hypo-methylated PCa|NT DMRs chr16 8797918187979417 0.00064571  −20.81292517 Hypo-methylated PCa|NT DMRs chr1687988087 88000776 4.79E−05 31.91991342 Hyper-methylated PCa|NT DMRschr16 88111053 88112406 0.003662905 −29.78095238 Hypo-methylated PCa|NTDMRs chr16 88123428 88124183 0.000122432 34.28311688 Hyper-methylatedPCa|NT DMRs chr16 88279309 88279491 0.004095673 −43.07142857Hypo-methylated PCa|NT DMRs chr16 88454593 88455226 6.52E−10 −47.8218126Hypo-methylated PCa|NT DMRs chr16 88499240 88501573 1.85E−10−25.72777778 Hypo-methylated PCa|NT DMRs chr16 88503436 885035240.000205174 −45.14880952 Hypo-methylated PCa|NT DMRs chr16 8850361188505415 2.55E−06 −23.79708141 Hypo-methylated PCa|NT DMRs chr1688518782 88518822 0.005968871 43.31428571 Hyper-methylated PCa|NT DMRschr16 88535803 88537416 0.00044133  24.84081633 Hyper-methylated PCa|NTDMRs chr16 88543358 88545582 0.000713083 20.70680272 Hyper-methylatedPCa|NT DMRs chr16 88565468 88566700 4.74E−10 32.31785714Hyper-methylated PCa|NT DMRs chr16 88575736 88576721 1.02E−05−29.54880952 Hypo-methylated PCa|NT DMRs chr16 88594340 885945290.001610287 −21.6875 Hypo-methylated PCa|NT DMRs chr16 88615339 886158918.93E−05 −27.7264881 Hypo-methylated PCa|NT DMRs chr16 88619410 886196010.005968871 27.71428571 Hyper-methylated PCa|NT DMRs chr16 8863764588638000 0.006225823 −27.99350649 Hypo-methylated PCa|NT DMRs chr1688665986 88666412 6.17E−06 28.94246032 Hyper-methylated PCa|NT DMRschr16 88715958 88719086 9.26E−14 39.17441193 Hyper-methylated PCa|NTDMRs chr16 88757871 88760007 0.000734562 30.43877551 Hyper-methylatedPCa|NT DMRs chr16 88765156 88771255 3.42E−18 40.06059415Hyper-methylated PCa|NT DMRs chr16 88794490 88794625 0.001969641−50.24489796 Hypo-methylated PCa|NT DMRs chr16 88812181 888126391.76E−06 54.7952381 Hyper-methylated PCa|NT DMRs chr16 88821701 888227480.000951499 −28.6 Hypo-methylated PCa|NT DMRs chr16 88844378 888455950.000247245 29.73214286 Hyper-methylated PCa|NT DMRs chr16 8885324388860289 3.85E−06 33.03519164 Hyper-methylated PCa|NT DMRs chr1688865937 88869438 4.61E−07 38.35277778 Hyper-methylated PCa|NT DMRschr16 88910430 88910690 0.000205174 −45.89285714 Hypo-methylated PCa|NTDMRs chr16 88985176 88985946 0.000104349 −24.19217687 Hypo-methylatedPCa|NT DMRs chr16 88993501 88993646 0.000215808 −21.11111111Hypo-methylated PCa|NT DMRs chr16 89000311 89006583 4.55E−07 20.3780506Hyper-methylated PCa|NT DMRs chr16 89023380 89025097 4.73E−0932.69277504 Hyper-methylated PCa|NT DMRs chr16 89033864 890342238.31E−07 32.86375661 Hyper-methylated PCa|NT DMRs chr16 8903596489037272 7.95E−05 −26.18205128 Hypo-methylated PCa|NT DMRs chr1689038036 89038197 0.000377317 −23.21428571 Hypo-methylated PCa|NT DMRschr16 89041832 89045234 1.34E−29 39.50926407 Hyper-methylated PCa|NTDMRs chr16 89047616 89047815 0.001969641 −23.27222222 Hypo-methylatedPCa|NT DMRs chr16 89050243 89050546 2.81E−09 29.98766234Hyper-methylated PCa|NT DMRs chr16 89050732 89052291 6.69E−05−35.39761905 Hypo-methylated PCa|NT DMRs chr16 89071807 890802823.81E−05 −27.62510823 Hypo-methylated PCa|NT DMRs chr16 8911756089120260 8.84E−05 −23.91227106 Hypo-methylated PCa|NT DMRs chr1689129561 89155984 2.41E−18 −20.75277986 Hypo-methylated PCa|NT DMRschr16 89220176 89221053 0.000443725 −38.65277778 Hypo-methylated PCa|NTDMRs chr16 89233831 89236933 0.000221737 −26.1637037 Hypo-methylatedPCa|NT DMRs chr16 89246570 89252105 8.37E−05 −20.38095238Hypo-methylated PCa|NT DMRs chr16 89261075 89261684 0.00296063834.60767196 Hyper-methylated PCa|NT DMRs chr16 89308450 893134650.004656267 −22.43760263 Hypo-methylated PCa|NT DMRs chr16 8938088789380946 0.001969641 −35.10714286 Hypo-methylated PCa|NT DMRs chr1689410450 89411755 0.003544378 −31.28984127 Hypo-methylated PCa|NT DMRschr16 89473080 89473324 0.00064571  20.91156463 Hyper-methylated PCa|NTDMRs chr16 89497164 89497628 0.000974795 −61.17916667 Hypo-methylatedPCa|NT DMRs chr16 89632402 89632762 1.11E−06 21.56666667Hyper-methylated PCa|NT DMRs chr16 89668771 89669085 0.00048038330.12962963 Hyper-methylated PCa|NT DMRs chr16 89674813 896759520.000972067 −48.75 Hypo-methylated PCa|NT DMRs chr16 89699579 896997900.001969641 −40.35714286 Hypo-methylated PCa|NT DMRs chr16 8977152089772073 1.69E−06 −50.83193277 Hypo-methylated PCa|NT DMRs chr1689909614 89909941 0.005968871 28.54112554 Hyper-methylated PCa|NT DMRschr16 89919706 89920026 0.000205174 −44.175 Hypo-methylated PCa|NT DMRschr16 90075183 90077803 6.48E−05 42.73333333 Hyper-methylated PCa|NTDMRs chr17 29849 30033 0.006694433 24.52857143 Hyper-methylated PCa|NTDMRs chr17 142406 143470 0.000981741 20.30933333 Hyper-methylated PCa|NTDMRs chr17 154408 154672 0.005968871 37.3647619 Hyper-methylated PCa|NTDMRs chr17 234709 235109 0.000130897 26.87844612 Hyper-methylated PCa|NTDMRs chr17 263170 266675 1.42E−05 52.42823129 Hyper-methylated PCa|NTDMRs chr17 398090 398330 0.00064571  46.91496599 Hyper-methylated PCa|NTDMRs chr17 435760 440964 0.000406205 20.20607553 Hyper-methylated PCa|NTDMRs chr17 500943 505389 0.005968871 45.98857143 Hyper-methylated PCa|NTDMRs chr17 643211 643752 0.00179283  53.83333333 Hyper-methylated PCa|NTDMRs chr17 695027 695096 0.000205174 40.58035714 Hyper-methylated PCa|NTDMRs chr17 782822 783752 0.003544378 −27.95396825 Hypo-methylated PCa|NTDMRs chr17 789739 790736 0.003314163 −35.58857143 Hypo-methylated PCa|NTDMRs chr17 904928 911213 0.000193691 −35.44662698 Hypo-methylated PCa|NTDMRs chr17 958978 960395 0.00071886  −31.58004535 Hypo-methylated PCa|NTDMRs chr17 990491 991611 2.78E−15 −47.48469388 Hypo-methylated PCa|NTDMRs chr17 1102425 1104766 1.34E−05 37.52585034 Hyper-methylated PCa|NTDMRs chr17 1131312 1132226 5.43E−11 27.34981685 Hyper-methylated PCa|NTDMRs chr17 1160033 1160311 1.53E−06 42.40340136 Hyper-methylated PCa|NTDMRs chr17 1191548 1193110 0.00064571  −22.42857143 Hypo-methylatedPCa|NT DMRs chr17 1251121 1272736 6.50E−06 −25.31666667 Hypo-methylatedPCa|NT DMRs chr17 1364119 1364319 0.004095673 −31.67063492Hypo-methylated PCa|NT DMRs chr17 1365444 1371366 8.31E−05 30.85769231Hyper-methylated PCa|NT DMRs chr17 1372480 1372730 0.000145366−31.00612245 Hypo-methylated PCa|NT DMRs chr17 1372751 13728920.00064571  27.76734694 Hyper-methylated PCa|NT DMRs chr17 13734741373944 0.000138104 31.06776557 Hyper-methylated PCa|NT DMRs chr171389602 1390934 5.71E−10 31.2195122 Hyper-methylated PCa|NT DMRs chr171420921 1420970 0.001969641 −38.55555556 Hypo-methylated PCa|NT DMRschr17 1462651 1465163 0.002885118 −30.85833333 Hypo-methylated PCa|NTDMRs chr17 1492163 1492298 6.98E−05 20.21598639 Hyper-methylated PCa|NTDMRs chr17 1507781 1508690 0.000173442 33.58670635 Hyper-methylatedPCa|NT DMRs chr17 1518236 1521487 1.30E−05 21.29809524 Hyper-methylatedPCa|NT DMRs chr17 1543014 1546412 2.71E−06 −52.86375661 Hypo-methylatedPCa|NT DMRs chr17 1547290 1549247 0.00109255  40.38660714Hyper-methylated PCa|NT DMRs chr17 1650284 1650961 0.001610287−26.32202381 Hypo-methylated PCa|NT DMRs chr17 1657530 16577470.007959104 27.39795918 Hyper-methylated PCa|NT DMRs chr17 18245951824636 0.004095673 −25.81904762 Hypo-methylated PCa|NT DMRs chr171843223 1843491 0.001985874 −20.23142857 Hypo-methylated PCa|NT DMRschr17 1880981 1881520 6.42E−10 29.71010453 Hyper-methylated PCa|NT DMRschr17 1903143 1903487 0.000972067 −26.91071429 Hypo-methylated PCa|NTDMRs chr17 1939737 1939853 0.005968871 −51.67428571 Hypo-methylatedPCa|NT DMRs chr17 2696048 2696222 0.000783791 39.47857143Hyper-methylated PCa|NT DMRs chr17 2699505 2700793 7.69E−07 48.27238095Hyper-methylated PCa|NT DMRs chr17 2755548 2756518 8.66E−09 36.44193548Hyper-methylated PCa|NT DMRs chr17 2838934 2839897 2.44E−10 49.76551227Hyper-methylated PCa|NT DMRs chr17 2866438 2881805 3.20E−05 −35.44393241Hypo-methylated PCa|NT DMRs chr17 2898695 2898871 0.000205174−63.85714286 Hypo-methylated PCa|NT DMRs chr17 3634937 36361510.003218673 −20.11538462 Hypo-methylated PCa|NT DMRs chr17 38176833820741 6.72E−11 48.62039072 Hyper-methylated PCa|NT DMRs chr17 38670923867443 5.77E−09 26.68571429 Hyper-methylated PCa|NT DMRs chr17 38799113880230 0.001115302 −36.30059524 Hypo-methylated PCa|NT DMRs chr173922850 3946272 0.008812478 −20.16772487 Hypo-methylated PCa|NT DMRschr17 4080331 4082167 0.002248181 29.47012987 Hyper-methylated PCa|NTDMRs chr17 4219263 4230877 0.007959104 −41.54761905 Hypo-methylatedPCa|NT DMRs chr17 4353144 4353352 0.001583613 29.00779221Hyper-methylated PCa|NT DMRs chr17 4437886 4439446 0.000203452−31.45204082 Hypo-methylated PCa|NT DMRs chr17 4443016 44447370.000293988 24.26165414 Hyper-methylated PCa|NT DMRs chr17 44627024469956 2.64E−05 −21.85407066 Hypo-methylated PCa|NT DMRs chr17 44985424498577 0.004095673 49.15 Hyper-methylated PCa|NT DMRs chr17 45534464553515 0.005968871 41.45714286 Hyper-methylated PCa|NT DMRs chr174641834 4642120 0.000305995 32.10714286 Hyper-methylated PCa|NT DMRschr17 4711284 4711782 0.001115302 −31.99107143 Hypo-methylated PCa|NTDMRs chr17 4831092 4835668 0.002225983 30.09714286 Hyper-methylatedPCa|NT DMRs chr17 4973685 4977345 4.96E−06 −32.11721612 Hypo-methylatedPCa|NT DMRs chr17 5019150 5020004 4.33E−05 22.21396825 Hyper-methylatedPCa|NT DMRs chr17 5402883 5403687 8.36E−06 −25.18740399 Hypo-methylatedPCa|NT DMRs chr17 5405260 5496850 2.00E−12 −26.91718427 Hypo-methylatedPCa|NT DMRs chr17 5516080 5609439 1.42E−09 −27.38534799 Hypo-methylatedPCa|NT DMRs chr17 5635333 5670876 2.05E−05 −40.97835498 Hypo-methylatedPCa|NT DMRs chr17 5689857 5703014 0.003314163 −28.87142857Hypo-methylated PCa|NT DMRs chr17 5846533 5973445 7.01E−09 −25.21412429Hypo-methylated PCa|NT DMRs chr17 6001587 6001955 0.001969641−37.71428571 Hypo-methylated PCa|NT DMRs chr17 6039466 60569200.002534928 −29.98 Hypo-methylated PCa|NT DMRs chr17 6064415 61361173.99E−11 −28.93428571 Hypo-methylated PCa|NT DMRs chr17 6155527 62978744.55E−15 −31.96263736 Hypo-methylated PCa|NT DMRs chr17 6338195 63395810.003893879 −28.28741497 Hypo-methylated PCa|NT DMRs chr17 65588516563630 2.06E−05 25.41879699 Hyper-methylated PCa|NT DMRs chr17 68989346899866 1.77E−17 30.5776455 Hyper-methylated PCa|NT DMRs chr17 69453916946780 2.27E−12 27.47997391 Hyper-methylated PCa|NT DMRs chr17 70041987004225 6.42E−05 −36.60634921 Hypo-methylated PCa|NT DMRs chr17 70059147006210 0.00017871  −22.40142857 Hypo-methylated PCa|NT DMRs chr177018443 7024314 0.00064571  41.08503401 Hyper-methylated PCa|NT DMRschr17 7077404 7081510 4.81E−06 32.91278195 Hyper-methylated PCa|NT DMRschr17 7082148 7093759 0.001399621 −24.11688312 Hypo-methylated PCa|NTDMRs chr17 7111321 7112269 0.000418479 −20.82633053 Hypo-methylatedPCa|NT DMRs chr17 7114953 7116883 0.00068166  −25.17440476Hypo-methylated PCa|NT DMRs chr17 7165624 7165658 0.001241245−20.47619048 Hypo-methylated PCa|NT DMRs chr17 7185382 7185630 1.12E−0721.75510204 Hyper-methylated PCa|NT DMRs chr17 7200469 72007370.000570576 −28.07671958 Hypo-methylated PCa|NT DMRs chr17 72400137240106 0.00064571  39.97959184 Hyper-methylated PCa|NT DMRs chr177308911 7312016 5.51E−08 46.04395604 Hyper-methylated PCa|NT DMRs chr177321689 7330192 0.000563378 −21.46992481 Hypo-methylated PCa|NT DMRschr17 7344027 7348666 1.64E−06 20.93660714 Hyper-methylated PCa|NT DMRschr17 7761950 7762833 6.69E−05 −29.42142857 Hypo-methylated PCa|NT DMRschr17 7806216 7807212 0.005968871 −41.48917749 Hypo-methylated PCa|NTDMRs chr17 7814173 7814877 3.11E−06 30.34880952 Hyper-methylated PCa|NTDMRs chr17 8123516 8123706 0.005968871 −51.47142857 Hypo-methylatedPCa|NT DMRs chr17 8229868 8230459 2.57E−11 33.71688312 Hyper-methylatedPCa|NT DMRs chr17 8311890 8311929 0.001969641 36.34920635Hyper-methylated PCa|NT DMRs chr17 9011726 9011774 0.00596887143.19428571 Hyper-methylated PCa|NT DMRs chr17 9018966 9019376 7.19E−0922.21980952 Hyper-methylated PCa|NT DMRs chr17 9066153 9066358 1.37E−09−30.90299824 Hypo-methylated PCa|NT DMRs chr17 9079154 9081870 5.20E−05−24.57619048 Hypo-methylated PCa|NT DMRs chr17 9135926 9143838 5.10E−1021.60593286 Hyper-methylated PCa|NT DMRs chr17 9144801 91449410.000974795 38.21428571 Hyper-methylated PCa|NT DMRs chr17 1285660412877651 1.01E−06 24.37722944 Hyper-methylated PCa|NT DMRs chr1712946737 12947377 0.006694433 −25.65761905 Hypo-methylated PCa|NT DMRschr17 13227831 13245284 0.005968871 −35.7 Hypo-methylated PCa|NT DMRschr17 13365965 13427776 1.34E−05 −25.81394558 Hypo-methylated PCa|NTDMRs chr17 13503848 13504034 0.006589535 22.95714286 Hyper-methylatedPCa|NT DMRs chr17 13553643 13557290 0.00068166  −28.78869048Hypo-methylated PCa|NT DMRs chr17 13950151 13950458 0.001969641−47.54761905 Hypo-methylated PCa|NT DMRs chr17 14059635 141155630.001050594 23.22786596 Hyper-methylated PCa|NT DMRs chr17 1420719314207539 1.37E−06 24.99614512 Hyper-methylated PCa|NT DMRs chr1714975063 15015703 5.99E−05 −25.63589744 Hypo-methylated PCa|NT DMRschr17 15849053 15849444 2.33E−10 22.32574405 Hyper-methylated PCa|NTDMRs chr17 16117366 16117689 0.001969641 −27.53174603 Hypo-methylatedPCa|NT DMRs chr17 16282382 16282455 0.005968871 −32.17142857Hypo-methylated PCa|NT DMRs chr17 16318945 16319187 0.00037547 26.09142857 Hyper-methylated PCa|NT DMRs chr17 16323248 163234820.001969641 44.02857143 Hyper-methylated PCa|NT DMRs chr17 1665005116650093 0.00064571  24.14285714 Hyper-methylated PCa|NT DMRs chr1716921326 16921487 0.005968871 21.6 Hyper-methylated PCa|NT DMRs chr1717110285 17110574 0.001896858 −29 Hypo-methylated PCa|NT DMRs chr1717204363 17204425 0.001969641 40.02380952 Hyper-methylated PCa|NT DMRschr17 17429414 17429982 2.05E−05 −34.01082251 Hypo-methylated PCa|NTDMRs chr17 17460868 17461169 0.001181579 −36.87755102 Hypo-methylatedPCa|NT DMRs chr17 17603437 17604103 1.66E−15 23.78532397Hyper-methylated PCa|NT DMRs chr17 17730932 17736460 0.002094  −21.56150794 Hypo-methylated PCa|NT DMRs chr17 18885080 188853290.001115302 −34.98214286 Hypo-methylated PCa|NT DMRs chr17 1890678618907708 2.88E−05 21.82849336 Hyper-methylated PCa|NT DMRs chr1718908404 18908427 0.00064571  −24.67346939 Hypo-methylated PCa|NT DMRschr17 19651508 19652057 0.000632596 −27.86493506 Hypo-methylated PCa|NTDMRs chr17 19911626 19911791 0.001181579 −25.7755102 Hypo-methylatedPCa|NT DMRs chr17 20902570 20913160 0.000251555 −27.25442177Hypo-methylated PCa|NT DMRs chr17 21366806 21368047 2.65E−08 22.3837535Hyper-methylated PCa|NT DMRs chr17 25676398 25676730 0.00145827222.13897243 Hyper-methylated PCa|NT DMRs chr17 25793824 257939210.001969641 55.36269841 Hyper-methylated PCa|NT DMRs chr17 2591464025915833 1.57E−07 −25.08349206 Hypo-methylated PCa|NT DMRs chr1726082735 26083043 0.00064571  −36.59857143 Hypo-methylated PCa|NT DMRschr17 26173143 26173408 0.004095673 52.90952381 Hyper-methylated PCa|NTDMRs chr17 26554245 26554488 0.007167999 22.34047619 Hyper-methylatedPCa|NT DMRs chr17 26557402 26557584 0.001969641 29.61904762Hyper-methylated PCa|NT DMRs chr17 26634050 26634336 7.47E−0625.02891156 Hyper-methylated PCa|NT DMRs chr17 26794808 267952942.86E−06 37.9031746 Hyper-methylated PCa|NT DMRs chr17 27168687 271688290.001969641 −43.75396825 Hypo-methylated PCa|NT DMRs chr17 2723087527248052 0.000585936 −24.75071429 Hypo-methylated PCa|NT DMRs chr1727451976 27452039 0.005968871 −28.05714286 Hypo-methylated PCa|NT DMRschr17 27943248 27943897 1.76E−06 36.94047619 Hyper-methylated PCa|NTDMRs chr17 28562435 28562660 4.59E−07 31.01680672 Hyper-methylatedPCa|NT DMRs chr17 29719101 29726026 3.06E−07 24.82324263Hyper-methylated PCa|NT DMRs chr17 30023371 30023459 0.001969641−57.52380952 Hypo-methylated PCa|NT DMRs chr17 30089774 300901930.001181579 −32.04081633 Hypo-methylated PCa|NT DMRs chr17 3021554930215813 0.005968871 33.46666667 Hyper-methylated PCa|NT DMRs chr1730243737 30243829 0.005968871 −28.72095238 Hypo-methylated PCa|NT DMRschr17 30676411 30676492 0.001969641 −31.18253968 Hypo-methylated PCa|NTDMRs chr17 30847262 30847348 0.001969641 46.38095238 Hyper-methylatedPCa|NT DMRs chr17 31649097 31776835 0.00071886  −25.8462585Hypo-methylated PCa|NT DMRs chr17 31806888 31825716 6.42E−05−26.48148148 Hypo-methylated PCa|NT DMRs chr17 32078874 324822832.39E−11 −27.14239418 Hypo-methylated PCa|NT DMRs chr17 3248281832483431 5.19E−07 −32.37179487 Hypo-methylated PCa|NT DMRs chr1732489947 32510198 0.007560755 −36.41071429 Hypo-methylated PCa|NT DMRschr17 32964325 32965263 2.17E−05 26.6447619 Hyper-methylated PCa|NT DMRschr17 32968855 32980623 0.006410012 −23.03846154 Hypo-methylated PCa|NTDMRs chr17 33446290 33446344 0.005513661 36.61488095 Hyper-methylatedPCa|NT DMRs chr17 33487618 33518536 0.000225685 −28.10045351Hypo-methylated PCa|NT DMRs chr17 33715844 33735419 0.001052963−29.72244898 Hypo-methylated PCa|NT DMRs chr17 33808126 338097920.00641359  −29.27698413 Hypo-methylated PCa|NT DMRs chr17 3405889534059374 0.001969641 24.99013605 Hyper-methylated PCa|NT DMRs chr1734077253 34077401 0.00064571  27.71428571 Hyper-methylated PCa|NT DMRschr17 34079855 34080266 0.007560755 29.38511905 Hyper-methylated PCa|NTDMRs chr17 34121869 34122078 4.32E−05 21.44727891 Hyper-methylatedPCa|NT DMRs chr17 34130944 34131414 0.00068166  −37.41071429Hypo-methylated PCa|NT DMRs chr17 34824909 34837275 2.02E−05−29.16613757 Hypo-methylated PCa|NT DMRs chr17 35014166 350149021.33E−09 23.84123113 Hyper-methylated PCa|NT DMRs chr17 3508432335085068 0.001969641 44.88650794 Hyper-methylated PCa|NT DMRs chr1735290924 35292442 8.19E−21 23.18267196 Hyper-methylated PCa|NT DMRschr17 35294171 35295321 5.35E−07 28.14609524 Hyper-methylated PCa|NTDMRs chr17 35423389 35424186 0.001254235 21.68058608 Hyper-methylatedPCa|NT DMRs chr17 35671538 35673094 0.000205174 −27.41964286Hypo-methylated PCa|NT DMRs chr17 35850854 35851134 0.00118157925.37755102 Hyper-methylated PCa|NT DMRs chr17 36184154 361930630.001210062 35.0085034 Hyper-methylated PCa|NT DMRs chr17 3658491736585790 2.94E−08 29.93972789 Hyper-methylated PCa|NT DMRs chr1736841923 36842035 0.000205174 23.16071429 Hyper-methylated PCa|NT DMRschr17 36898609 36898818 0.005968871 −36.5952381 Hypo-methylated PCa|NTDMRs chr17 37023588 37024783 0.00064571  32.31972789 Hyper-methylatedPCa|NT DMRs chr17 37045573 37048967 0.000342782 20.93082707Hyper-methylated PCa|NT DMRs chr17 37321375 37332007 1.76E−0623.97035147 Hyper-methylated PCa|NT DMRs chr17 37369289 373788130.000104435 −30.1276644 Hypo-methylated PCa|NT DMRs chr17 3771983037719914 0.001969641 26.21428571 Hyper-methylated PCa|NT DMRs chr1737764094 37764285 0.000124779 23.72619048 Hyper-methylated PCa|NT DMRschr17 37817230 37821665 3.28E−05 −24.11657509 Hypo-methylated PCa|NTDMRs chr17 37875774 37875847 0.005968871 27.74285714 Hyper-methylatedPCa|NT DMRs chr17 38100307 38100812 0.004505524 −22.08571429Hypo-methylated PCa|NT DMRs chr17 38212952 38213451 0.001969641−25.09126984 Hypo-methylated PCa|NT DMRs chr17 38334187 383346441.22E−09 39.42815126 Hyper-methylated PCa|NT DMRs chr17 3847302438473412 3.15E−07 −46.87301587 Hypo-methylated PCa|NT DMRs chr1738476024 38481227 0.001775064 31.88756614 Hyper-methylated PCa|NT DMRschr17 38487023 38488769 0.000158634 −25.99019608 Hypo-methylated PCa|NTDMRs chr17 38599056 38599621 0.005295761 20.53630952 Hyper-methylatedPCa|NT DMRs chr17 38774790 38775442 0.004505524 −34.15119048Hypo-methylated PCa|NT DMRs chr17 38935824 38936051 4.33E−05 26.35384615Hyper-methylated PCa|NT DMRs chr17 39551441 39557930 0.005968871−34.5447619 Hypo-methylated PCa|NT DMRs chr17 39780606 397821330.002111644 26.01648352 Hyper-methylated PCa|NT DMRs chr17 3996924039969580 6.66E−05 22.35273369 Hyper-methylated PCa|NT DMRs chr1740125571 40127709 0.000159287 −20.6254902 Hypo-methylated PCa|NT DMRschr17 40192161 40192483 2.02E−08 34.74537815 Hyper-methylated PCa|NTDMRs chr17 40221718 40224992 1.19E−05 24.09163059 Hyper-methylatedPCa|NT DMRs chr17 40259593 40260567 0.000583352 25.35555556Hyper-methylated PCa|NT DMRs chr17 40340825 40341505 0.00020517435.62916667 Hyper-methylated PCa|NT DMRs chr17 40440758 404415212.38E−10 43.47685185 Hyper-methylated PCa|NT DMRs chr17 4046342640465243 0.000285978 31.64380952 Hyper-methylated PCa|NT DMRs chr1740572399 40574560 6.77E−05 32.33333333 Hyper-methylated PCa|NT DMRschr17 40705975 40706061 0.001181579 −34.97278912 Hypo-methylated PCa|NTDMRs chr17 40723447 40723697 0.00064571  −51.3707483 Hypo-methylatedPCa|NT DMRs chr17 40811703 40811990 0.006589535 20.53619048Hyper-methylated PCa|NT DMRs chr17 40835778 40836801 0.002818478−20.49977324 Hypo-methylated PCa|NT DMRs chr17 40931996 409324450.000611234 −22.08507937 Hypo-methylated PCa|NT DMRs chr17 4117726541177495 3.19E−08 27.53690476 Hyper-methylated PCa|NT DMRs chr1741742803 41742993 0.005968871 20.13333333 Hyper-methylated PCa|NT DMRschr17 41770802 41779529 0.00068166  −26.19464286 Hypo-methylated PCa|NTDMRs chr17 42030536 42030962 0.000219415 20.43452381 Hyper-methylatedPCa|NT DMRs chr17 42246099 42248359 0.005425083 −31.66666667Hypo-methylated PCa|NT DMRs chr17 42336559 42336709 1.29E−05 41.11607143Hyper-methylated PCa|NT DMRs chr17 42357220 42357518 0.00992418628.36507937 Hyper-methylated PCa|NT DMRs chr17 42386058 423865151.66E−06 27.51177945 Hyper-methylated PCa|NT DMRs chr17 4243976142439985 0.005513661 35.21785714 Hyper-methylated PCa|NT DMRs chr1742452205 42453166 0.000218021 29.39550265 Hyper-methylated PCa|NT DMRschr17 42636124 42641018 2.20E−08 27.76587302 Hyper-methylated PCa|NTDMRs chr17 42685781 42685943 0.001969641 −54.67460317 Hypo-methylatedPCa|NT DMRs chr17 42835777 42836026 0.00266722  23.12745098Hyper-methylated PCa|NT DMRs chr17 42992709 43001467 0.002750151−24.35587302 Hypo-methylated PCa|NT DMRs chr17 43120934 431229680.002654087 −38.57380952 Hypo-methylated PCa|NT DMRs chr17 4319825843198760 4.90E−17 46.61335201 Hyper-methylated PCa|NT DMRs chr1743204387 43204802 0.001241245 32.74550265 Hyper-methylated PCa|NT DMRschr17 43221187 43221967 5.40E−09 31.13064713 Hyper-methylated PCa|NTDMRs chr17 43299633 43302819 0.000177981 26.74145658 Hyper-methylatedPCa|NT DMRs chr17 43311645 43319868 3.13E−10 −50.33217189Hypo-methylated PCa|NT DMRs chr17 43448920 43449280 3.92E−14 27.49028183Hyper-methylated PCa|NT DMRs chr17 43482264 43483327 0.005968871−29.01809524 Hypo-methylated PCa|NT DMRs chr17 43723749 437239200.001969641 44.78571429 Hyper-methylated PCa|NT DMRs chr17 4377212443787766 0.004553481 −23.95396825 Hypo-methylated PCa|NT DMRs chr1743860702 43861126 3.46E−11 20.10909091 Hyper-methylated PCa|NT DMRschr17 43901001 43901196 0.001969641 24.16190476 Hyper-methylated PCa|NTDMRs chr17 44845792 44848771 7.23E−08 26.02951334 Hyper-methylatedPCa|NT DMRs chr17 44953929 44972072 0.000535196 −26.82205514Hypo-methylated PCa|NT DMRs chr17 45772719 45773560 1.08E−05 33.67477954Hyper-methylated PCa|NT DMRs chr17 45778236 45781740 0.00622356 28.17559524 Hyper-methylated PCa|NT DMRs chr17 45785806 457867395.61E−12 −21.93438538 Hypo-methylated PCa|NT DMRs chr17 4582138845821894 0.000688325 −25.17765568 Hypo-methylated PCa|NT DMRs chr1745897102 45897179 0.008482405 29.6 Hyper-methylated PCa|NT DMRs chr1745924164 45925265 4.01E−13 26.26634492 Hyper-methylated PCa|NT DMRschr17 45928959 45929684 0.000271988 38.50634921 Hyper-methylated PCa|NTDMRs chr17 46027094 46035273 0.002437742 −38.21693122 Hypo-methylatedPCa|NT DMRs chr17 46128598 46132436 0.000118733 −24.66666667Hypo-methylated PCa|NT DMRs chr17 46645891 46646578 1.42E−05 33.83877551Hyper-methylated PCa|NT DMRs chr17 46663394 46671501 1.31E−11 32.6890377Hyper-methylated PCa|NT DMRs chr17 46673604 46675173 4.37E−06 24.5264652Hyper-methylated PCa|NT DMRs chr17 46679338 46679594 0.005968871−31.59714286 Hypo-methylated PCa|NT DMRs chr17 46696993 466975840.000175653 −23.62962963 Hypo-methylated PCa|NT DMRs chr17 4671926546719516 6.98E−05 24.76394558 Hyper-methylated PCa|NT DMRs chr1746723587 46723790 0.005685503 21.10952381 Hyper-methylated PCa|NT DMRschr17 47060483 47066626 0.003093471 −23.95428571 Hypo-methylated PCa|NTDMRs chr17 47287931 47288173 0.003448944 24.07755102 Hyper-methylatedPCa|NT DMRs chr17 47515946 47518536 5.66E−05 27.71315193Hyper-methylated PCa|NT DMRs chr17 47519662 47535178 0.003152456−22.63015873 Hypo-methylated PCa|NT DMRs chr17 47547201 475477680.002400984 20.32063492 Hyper-methylated PCa|NT DMRs chr17 4798502947992711 3.64E−14 35.02892416 Hyper-methylated PCa|NT DMRs chr1748046982 48049652 7.81E−06 23.03174603 Hyper-methylated PCa|NT DMRschr17 48071824 48072086 1.46E−06 20.1702381 Hyper-methylated PCa|NT DMRschr17 48222642 48226084 0.004266047 30.61515152 Hyper-methylated PCa|NTDMRs chr17 48422457 48422588 0.008482405 −56.47142857 Hypo-methylatedPCa|NT DMRs chr17 48545943 48546774 5.14E−13 24.86825397Hyper-methylated PCa|NT DMRs chr17 48559485 48560818 9.85E−06−20.12637363 Hypo-methylated PCa|NT DMRs chr17 48586118 485861840.000974795 41.94642857 Hyper-methylated PCa|NT DMRs chr17 4862796948628618 0.000766778 −38.77819549 Hypo-methylated PCa|NT DMRs chr1748639261 48639794 0.000106046 26.94047619 Hyper-methylated PCa|NT DMRschr17 48712473 48715144 0.00018063  24.7552795 Hyper-methylated PCa|NTDMRs chr17 48762191 48777009 6.19E−07 −33.7567619 Hypo-methylated PCa|NTDMRs chr17 48911577 48912509 1.34E−05 −25.16666667 Hypo-methylatedPCa|NT DMRs chr17 48999145 49007170 0.009503366 37.10714286Hyper-methylated PCa|NT DMRs chr17 49449345 49539553 0.002330844−29.77210884 Hypo-methylated PCa|NT DMRs chr17 49968510 500247840.005513661 −38.38911565 Hypo-methylated PCa|NT DMRs chr17 5390822553972771 0.007679542 25.11111111 Hyper-methylated PCa|NT DMRs chr1754755992 54756199 1.29E−05 34.9829932 Hyper-methylated PCa|NT DMRs chr1754776653 54787992 8.64E−05 −47.94315476 Hypo-methylated PCa|NT DMRschr17 55184069 55207150 0.000443725 −23.04104308 Hypo-methylated PCa|NTDMRs chr17 55609803 55615176 0.000783791 38.25904762 Hyper-methylatedPCa|NT DMRs chr17 55740465 55740792 0.000715461 −22.0047619Hypo-methylated PCa|NT DMRs chr17 55801427 55801633 0.00068166 28.44642857 Hyper-methylated PCa|NT DMRs chr17 55820329 558223060.007959104 20.55170068 Hyper-methylated PCa|NT DMRs chr17 5591727155924746 0.002400984 −23.94412698 Hypo-methylated PCa|NT DMRs chr1755968004 55968073 0.008482405 −21.95238095 Hypo-methylated PCa|NT DMRschr17 56220091 56233772 1.53E−05 −20.96560847 Hypo-methylated PCa|NTDMRs chr17 56245816 56255755 0.001451132 −24.1042328 Hypo-methylatedPCa|NT DMRs chr17 56405141 56421930 1.63E−09 44.32843915Hyper-methylated PCa|NT DMRs chr17 56591006 56591545 0.00196964123.47619048 Hyper-methylated PCa|NT DMRs chr17 56709848 567100500.003400006 −22.53061224 Hypo-methylated PCa|NT DMRs chr17 5674408756744491 0.000858283 −20.22896825 Hypo-methylated PCa|NT DMRs chr1759473114 59475769 1.40E−34 33.47424812 Hyper-methylated PCa|NT DMRschr17 59652327 59652568 0.000205174 −25.16369048 Hypo-methylated PCa|NTDMRs chr17 60757293 60757347 0.001850915 −30.87202381 Hypo-methylatedPCa|NT DMRs chr17 60757992 60758147 1.42E−05 −31.49013605Hypo-methylated PCa|NT DMRs chr17 60881193 60885780 3.74E−06 31.92626263Hyper-methylated PCa|NT DMRs chr17 61354673 61354750 0.00409567325.88095238 Hyper-methylated PCa|NT DMRs chr17 61497518 614979530.005968871 49.06952381 Hyper-methylated PCa|NT DMRs chr17 6150962061510041 0.000205174 −49.6875 Hypo-methylated PCa|NT DMRs chr17 6155386461554253 6.69E−14 35.46235828 Hyper-methylated PCa|NT DMRs chr1761614986 61616032 8.40E−08 34.1952381 Hyper-methylated PCa|NT DMRs chr1761773963 61776940 4.36E−11 31.10787879 Hyper-methylated PCa|NT DMRschr17 61817252 61817355 0.000632596 −51.70822511 Hypo-methylated PCa|NTDMRs chr17 62008831 62010012 5.92E−06 42.94593838 Hyper-methylatedPCa|NT DMRs chr17 62038982 62039170 0.000133909 23.32142857Hyper-methylated PCa|NT DMRs chr17 62065549 62066996 1.43E−07−26.43446115 Hypo-methylated PCa|NT DMRs chr17 62141224 621414010.006225823 24.32727273 Hyper-methylated PCa|NT DMRs chr17 6277364062777838 1.53E−55 33.94868316 Hyper-methylated PCa|NT DMRs chr1763434457 63438808 0.002585277 25.64880952 Hyper-methylated PCa|NT DMRschr17 64671880 64672869 6.83E−06 −57.02436975 Hypo-methylated PCa|NTDMRs chr17 64954408 64954523 0.003892841 −52.76772487 Hypo-methylatedPCa|NT DMRs chr17 65796053 65803210 0.001518408 −24.77886905Hypo-methylated PCa|NT DMRs chr17 66194534 66195112 2.31E−05 21.07032967Hyper-methylated PCa|NT DMRs chr17 66283529 66286130 0.00904940228.15428571 Hyper-methylated PCa|NT DMRs chr17 66308871 663092590.002437742 34.32804233 Hyper-methylated PCa|NT DMRs chr17 6687263266876198 1.11E−05 −27.03030303 Hypo-methylated PCa|NT DMRs chr1769971349 69971640 0.00064571  −26.58843537 Hypo-methylated PCa|NT DMRschr17 70119459 70120379 1.45E−23 28.26400227 Hyper-methylated PCa|NTDMRs chr17 70376170 70384952 0.000121489 25.52619048 Hyper-methylatedPCa|NT DMRs chr17 71190109 71197723 0.002424722 −34.44077381Hypo-methylated PCa|NT DMRs chr17 71201722 71201801 0.005968871−45.37142857 Hypo-methylated PCa|NT DMRs chr17 71286873 712881600.002097193 39.8244898 Hyper-methylated PCa|NT DMRs chr17 7139546271398377 0.00358897  24.49015873 Hyper-methylated PCa|NT DMRs chr1771622064 71627573 0.001336455 25.21428571 Hyper-methylated PCa|NT DMRschr17 71641633 71642099 0.003034084 −25.12414966 Hypo-methylated PCa|NTDMRs chr17 71760111 71773459 0.001589893 −20.91309524 Hypo-methylatedPCa|NT DMRs chr17 71948480 71949246 2.39E−16 21.18130252Hyper-methylated PCa|NT DMRs chr17 72090277 72098713 0.002097193−27.19931973 Hypo-methylated PCa|NT DMRs chr17 72209865 722103752.22E−11 37.48730159 Hyper-methylated PCa|NT DMRs chr17 7228418572301189 0.000377317 −25.84047619 Hypo-methylated PCa|NT DMRs chr1772343982 72346992 1.08E−06 −23.11142857 Hypo-methylated PCa|NT DMRschr17 72462522 72463272 4.11E−07 45.86466165 Hyper-methylated PCa|NTDMRs chr17 72464888 72476525 5.18E−06 −20.04550265 Hypo-methylatedPCa|NT DMRs chr17 72535504 72545983 4.89E−07 −20.97047619Hypo-methylated PCa|NT DMRs chr17 72645290 72657724 2.94E−06−29.88359788 Hypo-methylated PCa|NT DMRs chr17 72707221 727088850.001181579 40.71428571 Hyper-methylated PCa|NT DMRs chr17 7273698172741459 0.002802605 −26.41176471 Hypo-methylated PCa|NT DMRs chr1772755638 72756260 0.005968871 20.88190476 Hyper-methylated PCa|NT DMRschr17 72782308 72786474 1.50E−05 32.41704261 Hyper-methylated PCa|NTDMRs chr17 72848842 72849368 6.45E−05 21.94313725 Hyper-methylatedPCa|NT DMRs chr17 72857995 72858033 0.007959104 20.69387755Hyper-methylated PCa|NT DMRs chr17 72913566 72916435 3.90E−1026.47706767 Hyper-methylated PCa|NT DMRs chr17 73200735 732010680.007560755 −28.86796537 Hypo-methylated PCa|NT DMRs chr17 7332129973323321 0.002585277 21.1875 Hyper-methylated PCa|NT DMRs chr17 7343718973440280 0.005122815 −31.19264069 Hypo-methylated PCa|NT DMRs chr1773494058 73494362 0.000205174 41.96428571 Hyper-methylated PCa|NT DMRschr17 73545489 73553691 7.34E−05 −39.05555556 Hypo-methylated PCa|NTDMRs chr17 73717684 73717837 0.003871035 −21.28373016 Hypo-methylatedPCa|NT DMRs chr17 73824171 73824344 0.005968871 33.46666667Hyper-methylated PCa|NT DMRs chr17 73838733 73841195 0.00124517841.5202381 Hyper-methylated PCa|NT DMRs chr17 73992997 739935170.000974795 44.4672619 Hyper-methylated PCa|NT DMRs chr17 7399629973997315 0.000122432 −26.41788932 Hypo-methylated PCa|NT DMRs chr1773999632 74001745 0.001181579 −55.0755102 Hypo-methylated PCa|NT DMRschr17 74032659 74033034 0.00064571  −55.6244898 Hypo-methylated PCa|NTDMRs chr17 74128537 74128951 0.000286238 −42.08937729 Hypo-methylatedPCa|NT DMRs chr17 74136213 74136587 3.21E−14 32.79128482Hyper-methylated PCa|NT DMRs chr17 74235859 74236109 2.04E−0525.94642857 Hyper-methylated PCa|NT DMRs chr17 74267548 742687600.009214933 27.4789916 Hyper-methylated PCa|NT DMRs chr17 7427512574275552 0.005968871 −30.58791209 Hypo-methylated PCa|NT DMRs chr1774377011 74378569 1.21E−07 48.6210084 Hyper-methylated PCa|NT DMRs chr1774485765 74490064 0.001054317 39.36054422 Hyper-methylated PCa|NT DMRschr17 74527294 74529730 0.004178506 −32.06577381 Hypo-methylated PCa|NTDMRs chr17 74557626 74565009 0.000960149 29.15535714 Hyper-methylatedPCa|NT DMRs chr17 74566041 74566431 0.003892841 −36.43121693Hypo-methylated PCa|NT DMRs chr17 74822659 74823027 2.86E−05 29.57142857Hyper-methylated PCa|NT DMRs chr17 74994454 74994805 6.42E−05 47.8Hyper-methylated PCa|NT DMRs chr17 75074776 75079364 0.007497996−20.92857143 Hypo-methylated PCa|NT DMRs chr17 75231604 752318160.000481535 53.50793651 Hyper-methylated PCa|NT DMRs chr17 7528193675282041 0.001969641 40.90408163 Hyper-methylated PCa|NT DMRs chr1775311663 75312391 0.001969641 48.9484127 Hyper-methylated PCa|NT DMRschr17 75313789 75319024 0.003917805 24.04537815 Hyper-methylated PCa|NTDMRs chr17 75385167 75387251 7.59E−06 34.81994048 Hyper-methylatedPCa|NT DMRs chr17 75421158 75422626 0.000128095 31.29980159Hyper-methylated PCa|NT DMRs chr17 75448405 75450254 0.00043134528.65297619 Hyper-methylated PCa|NT DMRs chr17 75450700 754625361.68E−12 32.7140625 Hyper-methylated PCa|NT DMRs chr17 75468686 754714910.00064571  35.1047619 Hyper-methylated PCa|NT DMRs chr17 7552325575523479 0.001344447 −36.55357143 Hypo-methylated PCa|NT DMRs chr1775530879 75540041 5.46E−05 −22.39047619 Hypo-methylated PCa|NT DMRschr17 75567588 75568711 0.000364072 30.41208791 Hyper-methylated PCa|NTDMRs chr17 75652314 75674045 6.72E−09 −24.59408369 Hypo-methylatedPCa|NT DMRs chr17 75703130 75705285 3.39E−05 −30.92770563Hypo-methylated PCa|NT DMRs chr17 75751822 75759239 0.001181579−42.10204082 Hypo-methylated PCa|NT DMRs chr17 75805015 758080380.007560755 −21.22261905 Hypo-methylated PCa|NT DMRs chr17 7581867575820648 0.001709403 −22.45416667 Hypo-methylated PCa|NT DMRs chr1775827381 75827782 6.42E−05 −23.52380952 Hypo-methylated PCa|NT DMRschr17 75842522 75843624 0.002585277 32.10714286 Hyper-methylated PCa|NTDMRs chr17 75865566 75865990 0.005186056 28.64809524 Hyper-methylatedPCa|NT DMRs chr17 76112056 76112134 0.005968871 40.4 Hyper-methylatedPCa|NT DMRs chr17 76117002 76124173 4.26E−06 23.72311111Hyper-methylated PCa|NT DMRs chr17 76126263 76133937 2.95E−17 30.1315735Hyper-methylated PCa|NT DMRs chr17 76140951 76141577 0.000161233−40.37428571 Hypo-methylated PCa|NT DMRs chr17 76160493 761605490.005968871 −24.57619048 Hypo-methylated PCa|NT DMRs chr17 7616749576167900 0.000570576 −22.52910053 Hypo-methylated PCa|NT DMRs chr1776170950 76171881 3.80E−06 −34.27113997 Hypo-methylated PCa|NT DMRschr17 76172781 76172850 6.42E−05 35.3015873 Hyper-methylated PCa|NT DMRschr17 76227803 76228830 1.24E−10 25.5248227 Hyper-methylated PCa|NT DMRschr17 76361174 76361451 0.000149331 39.68831169 Hyper-methylated PCa|NTDMRs chr17 76361762 76362800 2.03E−06 −22.60888889 Hypo-methylatedPCa|NT DMRs chr17 76380937 76385429 0.00179283  35.45892857Hyper-methylated PCa|NT DMRs chr17 76472324 76478296 3.20E−06−22.53501401 Hypo-methylated PCa|NT DMRs chr17 76479834 764813810.008083098 24.7047619 Hyper-methylated PCa|NT DMRs chr17 7658644176596569 0.000149336 −24.89411765 Hypo-methylated PCa|NT DMRs chr1776646502 76654718 0.00023371  −35.09215686 Hypo-methylated PCa|NT DMRschr17 76661489 76662907 0.001181579 39.55102041 Hyper-methylated PCa|NTDMRs chr17 76712831 76713341 0.000305995 −47.15666667 Hypo-methylatedPCa|NT DMRs chr17 76886583 76887592 2.86E−05 49.75824176Hyper-methylated PCa|NT DMRs chr17 76953441 76953488 0.005968871−52.56571429 Hypo-methylated PCa|NT DMRs chr17 76970989 769717316.16E−06 −45.53869048 Hypo-methylated PCa|NT DMRs chr17 7702107977021828 0.000112344 −34.15396825 Hypo-methylated PCa|NT DMRs chr1777092717 77092978 0.009924186 −29.52698413 Hypo-methylated PCa|NT DMRschr17 77099798 77100321 0.000243577 30.77113095 Hyper-methylated PCa|NTDMRs chr17 77110607 77111617 0.000149244 −37.78630952 Hypo-methylatedPCa|NT DMRs chr17 77121790 77123774 6.68E−05 −25.98039216Hypo-methylated PCa|NT DMRs chr17 77145368 77152976 1.47E−12−31.54484127 Hypo-methylated PCa|NT DMRs chr17 77175610 771775045.87E−08 −25.47380952 Hypo-methylated PCa|NT DMRs chr17 7719076877215871 7.72E−13 −22.84778613 Hypo-methylated PCa|NT DMRs chr1777285423 77293777 1.13E−05 −28.46813187 Hypo-methylated PCa|NT DMRschr17 77315523 77317949 0.000974795 −33.95119048 Hypo-methylated PCa|NTDMRs chr17 77325839 77365381 9.56E−16 −28.140764 Hypo-methylated PCa|NTDMRs chr17 77395158 77398979 0.00010532  −22.84920635 Hypo-methylatedPCa|NT DMRs chr17 77536253 77546171 8.77E−12 −22.04505495Hypo-methylated PCa|NT DMRs chr17 77660432 77660752 0.00742837620.49450549 Hyper-methylated PCa|NT DMRs chr17 77674065 776742170.001969641 34.23809524 Hyper-methylated PCa|NT DMRs chr17 7772215077722457 7.48E−11 22.51587302 Hyper-methylated PCa|NT DMRs chr1777746456 77747566 0.001171269 −27.64935065 Hypo-methylated PCa|NT DMRschr17 77755583 77755966 0.000480383 54.88624339 Hyper-methylated PCa|NTDMRs chr17 77764781 77766130 1.40E−17 36.97878028 Hyper-methylatedPCa|NT DMRs chr17 77788000 77788439 6.42E−05 34.53968254Hyper-methylated PCa|NT DMRs chr17 77893070 77894006 2.75E−07−37.50272109 Hypo-methylated PCa|NT DMRs chr17 77894032 778950920.000145094 27.40079365 Hyper-methylated PCa|NT DMRs chr17 7789885977899654 0.003448944 −21.15391705 Hypo-methylated PCa|NT DMRs chr1777909301 77911936 0.00064571  −28.73015873 Hypo-methylated PCa|NT DMRschr17 77922731 77923161 0.000187865 −25.10277778 Hypo-methylated PCa|NTDMRs chr17 77960558 77960715 3.20E−06 −46.69187675 Hypo-methylatedPCa|NT DMRs chr17 77966181 77966505 0.006190613 −20.97835498Hypo-methylated PCa|NT DMRs chr17 77982180 77983542 1.17E−05−21.67728938 Hypo-methylated PCa|NT DMRs chr17 77996733 780091603.17E−07 −24.01991342 Hypo-methylated PCa|NT DMRs chr17 7804137778044790 3.26E−10 −34.42528736 Hypo-methylated PCa|NT DMRs chr1778161083 78161860 4.84E−06 −44.61772487 Hypo-methylated PCa|NT DMRschr17 78169924 78169998 0.007628253 29.18707483 Hyper-methylated PCa|NTDMRs chr17 78235448 78251123 0.006791526 23.41927438 Hyper-methylatedPCa|NT DMRs chr17 78262477 78262609 0.001969641 23.63730159Hyper-methylated PCa|NT DMRs chr17 78424123 78424297 0.001115302−29.16964286 Hypo-methylated PCa|NT DMRs chr17 78754323 787552150.000205174 50.53869048 Hyper-methylated PCa|NT DMRs chr17 7884506678847753 3.79E−05 25.11287478 Hyper-methylated PCa|NT DMRs chr1778853824 78854059 0.001789867 32.27195767 Hyper-methylated PCa|NT DMRschr17 78860036 78860413 9.81E−07 25.53333333 Hyper-methylated PCa|NTDMRs chr17 78915627 78916403 0.000729529 −34.82380952 Hypo-methylatedPCa|NT DMRs chr17 78957505 78962207 0.001241245 −21.7956044Hypo-methylated PCa|NT DMRs chrl7 78963414 78965075 0.005968871−23.02579365 Hypo-methylated PCa|NT DMRs chr17 78974683 789752320.00080034  −29.84017857 Hypo-methylated PCa|NT DMRs chr17 7899935079001859 3.75E−06 −26.14307359 Hypo-methylated PCa|NT DMRs chr1779024835 79025692 0.000339627 −23.70595238 Hypo-methylated PCa|NT DMRschr17 79028749 79041678 7.45E−07 −21.17080745 Hypo-methylated PCa|NTDMRs chr17 79042879 79043265 2.31E−05 −34.92307692 Hypo-methylatedPCa|NT DMRs chr17 79066746 79067196 6.29E−09 −23.35185185Hypo-methylated PCa|NT DMRs chr17 79095365 79098041 8.33E−28−47.30533752 Hypo-methylated PCa|NT DMRs chr17 79125228 791253240.001093287 28.08253968 Hyper-methylated PCa|NT DMRs chr17 7913357379134646 5.31E−06 22.31492063 Hyper-methylated PCa|NT DMRs chr1779138730 79139351 5.50E−05 −21.84210526 Hypo-methylated PCa|NT DMRschr17 79213998 79214135 0.000205174 −27 Hypo-methylated PCa|NT DMRschr17 79258585 79260095 5.15E−08 37.69627976 Hyper-methylated PCa|NTDMRs chr17 79261627 79262123 1.42E−05 44.06292517 Hyper-methylatedPCa|NT DMRs chr17 79283832 79283926 0.000122432 24.35497835Hyper-methylated PCa|NT DMRs chr17 79297386 79297773 0.00011769945.94805195 Hyper-methylated PCa|NT DMRs chr17 79375341 793758092.86E−05 43.30769231 Hyper-methylated PCa|NT DMRs chr17 7939531779396928 0.006976128 21.91764706 Hyper-methylated PCa|NT DMRs chr1779404294 79409509 7.39E−08 23.66557272 Hyper-methylated PCa|NT DMRschr17 79427225 79428894 1.27E−19 35.98879552 Hyper-methylated PCa|NTDMRs chr17 79450263 79451215 1.28E−05 28.67654987 Hyper-methylatedPCa|NT DMRs chr17 79503591 79504469 2.51E−23 30.19090354Hyper-methylated PCa|NT DMRs chr17 79619878 79620666 0.00032872 34.90884354 Hyper-methylated PCa|NT DMRs chr17 79626532 796269721.97E−05 −53.22619048 Hypo-methylated PCa|NT DMRs chr17 7964956779649845 0.002585277 −28.875 Hypo-methylated PCa|NT DMRs chr17 7965201579653971 2.56E−05 −30.54444444 Hypo-methylated PCa|NT DMRs chr1779668608 79668747 4.06E−05 −23.95535714 Hypo-methylated PCa|NT DMRschr17 79679794 79681312 0.002562638 −39.30873016 Hypo-methylated PCa|NTDMRs chr17 79694463 79694557 0.003464153 −44.50649351 Hypo-methylatedPCa|NT DMRs chr17 79701435 79701791 3.14E−05 −24.77142857Hypo-methylated PCa|NT DMRs chr17 79707782 79708510 1.44E−05 28.48245614Hyper-methylated PCa|NT DMRs chr17 79763216 79766197 0.001000355−22.28666667 Hypo-methylated PCa|NT DMRs chr17 79873535 798738170.000392715 −22.6047619 Hypo-methylated PCa|NT DMRs chr17 7988061479883766 4.43E−06 25.99514286 Hyper-methylated PCa|NT DMRs chr1779887989 79888329 0.006410012 −20.55367965 Hypo-methylated PCa|NT DMRschr17 79897923 79898002 4.43E−05 −29.19413919 Hypo-methylated PCa|NTDMRs chr17 79919556 79920603 5.05E−07 28.08444444 Hyper-methylatedPCa|NT DMRs chr17 79949256 79950562 1.26E−06 −35.66954596Hypo-methylated PCa|NT DMRs chr17 79977130 79979628 5.04E−05−30.23619048 Hypo-methylated PCa|NT DMRs chr17 79991872 799928552.37E−05 −35.01333333 Hypo-methylated PCa|NT DMRs chr17 8001254980022967 3.24E−12 −28.54686248 Hypo-methylated PCa|NT DMRs chr1780030597 80054365  4.93E−116 −35.97386377 Hypo-methylated PCa|NT DMRschr17 80174767 80175804 7.84E−06 39.97714286 Hyper-methylated PCa|NTDMRs chr17 80185958 80186766 3.44E−12 38.51873706 Hyper-methylatedPCa|NT DMRs chr17 80215659 80225606 0.008497149 −24.8047619Hypo-methylated PCa|NT DMRs chr17 80253604 80254273 0.00064571 −38.41156463 Hypo-methylated PCa|NT DMRs chr17 80259204 802634215.89E−11 26.61152882 Hyper-methylated PCa|NT DMRs chr17 8026788680268482 0.001344447 −23.32142857 Hypo-methylated PCa|NT DMRs chr1780292191 80292796 5.44E−05 28.75 Hyper-methylated PCa|NT DMRs chr1780308407 80309325 0.00023371  24.25578231 Hyper-methylated PCa|NT DMRschr17 80341259 80343302 1.44E−05 −27.50822511 Hypo-methylated PCa|NTDMRs chr17 80345995 80346517 0.000339627 −21.5077381 Hypo-methylatedPCa|NT DMRs chr17 80357183 80358923 0.000117699 49.29437229Hyper-methylated PCa|NT DMRs chr17 80593887 80597555 1.97E−05−51.6452381 Hypo-methylated PCa|NT DMRs chr17 80636580 806366780.000205174 −33.88690476 Hypo-methylated PCa|NT DMRs chr17 8066064980660846 0.001969641 −51.43253968 Hypo-methylated PCa|NT DMRs chr1780846867 80850475 0.000107028 −23.90029762 Hypo-methylated PCa|NT DMRschr17 80923382 80926233 0.002097193 −38.26530612 Hypo-methylated PCa|NTDMRs chr17 80943851 80944094 0.000474737 47.2037037 Hyper-methylatedPCa|NT DMRs chr17 80981902 80982435 0.000286238 33.8484127Hyper-methylated PCa|NT DMRs chr17 81025841 81026757 6.69E−05 −33.34Hypo-methylated PCa|NT DMRs chr17 81026919 81027222 0.00011769950.30735931 Hyper-methylated PCa|NT DMRs chr17 81047008 810478554.36E−12 −48.49659864 Hypo-methylated PCa|NT DMRs chr17 8105446981055049 3.20E−05 −39.6292517 Hypo-methylated PCa|NT DMRs chr17 8105706281057715 0.002285154 22.19761905 Hyper-methylated PCa|NT DMRs chr1781071958 81072216 1.76E−06 −28.04761905 Hypo-methylated PCa|NT DMRschr17 81083398 81085505 1.93E−10 −21.96056166 Hypo-methylated PCa|NTDMRs chr17 81143889 81148046 3.10E−08 37.56075534 Hyper-methylatedPCa|NT DMRs chr18 465930 466038 0.001969641 22.07142857 Hyper-methylatedPCa|NT DMRs chr18 501047 501653 0.009924186 22.09899749 Hyper-methylatedPCa|NT DMRs chr18 514363 514574 0.007560755 −21.24155844 Hypo-methylatedPCa|NT DMRs chr18 904493 905101 8.31E−07 21.65538847 Hyper-methylatedPCa|NT DMRs chr18 951739 951983 0.005968871 −37.13333333 Hypo-methylatedPCa|NT DMRs chr18 1676045 1955468 1.01E−14 −36.68706004 Hypo-methylatedPCa|NT DMRs chr18 2033276 2192354 2.01E−07 −39.28928571 Hypo-methylatedPCa|NT DMRs chr18 2270060 2471687 1.35E−11 −30.58783069 Hypo-methylatedPCa|NT DMRs chr18 2858012 2859081 0.006410012 35.35654762Hyper-methylated PCa|NT DMRs chr18 3411918 3412165 0.00014900629.23203463 Hyper-methylated PCa|NT DMRs chr18 3499025 3499861 1.46E−0841.60297619 Hyper-methylated PCa|NT DMRs chr18 5635801 57614290.000987641 −29.20925926 Hypo-methylated PCa|NT DMRs chr18 59769886113039 1.88E−07 −25.18484848 Hypo-methylated PCa|NT DMRs chr18 62521406268263 6.42E−05 −21.95238095 Hypo-methylated PCa|NT DMRs chr18 64139606414460 1.54E−11 27.59716312 Hyper-methylated PCa|NT DMRs chr18 84799888480174 0.001969641 −41.60714286 Hypo-methylated PCa|NT DMRs chr188706693 8707546 6.35E−16 21.01549509 Hyper-methylated PCa|NT DMRs chr188990408 8990902 1.97E−05 −40.68315018 Hypo-methylated PCa|NT DMRs chr189404630 9404870 1.97E−05 57.23809524 Hyper-methylated PCa|NT DMRs chr189434059 9434604 0.000252289 33.14557823 Hyper-methylated PCa|NT DMRschr18 9735310 9735576 0.000205174 62.1452381 Hyper-methylated PCa|NTDMRs chr18 9994457 9994840 1.11E−05 −25.95238095 Hypo-methylated PCa|NTDMRs chr18 10031031 10031433 1.91E−05 −29.28823529 Hypo-methylatedPCa|NT DMRs chr18 10044815 10045873 5.94E−06 −28.79220779Hypo-methylated PCa|NT DMRs chr18 10154168 10165815 4.11E−07−25.73082707 Hypo-methylated PCa|NT DMRs chr18 10205334 102054580.001969641 −40.38095238 Hypo-methylated PCa|NT DMRs chr18 1191291111913228 0.000205174 −44.7202381 Hypo-methylated PCa|NT DMRs chr1811947339 11947990 6.98E−09 36.44109347 Hyper-methylated PCa|NT DMRschr18 11972539 11973184 4.45E−08 47.08984127 Hyper-methylated PCa|NTDMRs chr18 12030311 12038759 1.23E−07 30.60260771 Hyper-methylatedPCa|NT DMRs chr18 12254366 12258991 0.001789867 23.57812098Hyper-methylated PCa|NT DMRs chr18 12304718 12305349 1.97E−05−50.91857143 Hypo-methylated PCa|NT DMRs chr18 13125696 131276280.000133627 −43.75272109 Hypo-methylated PCa|NT DMRs chr18 1360983813612631 5.61E−06 29.99293924 Hyper-methylated PCa|NT DMRs chr1814089936 14090087 0.003622801 −45.35714286 Hypo-methylated PCa|NT DMRschr18 18820939 18821478 0.000551093 27.49166667 Hyper-methylated PCa|NTDMRs chr18 19928268 19928436 0.00064571  25.63265306 Hyper-methylatedPCa|NT DMRs chr18 20139815 20140198 3.43E−06 20.00744048Hyper-methylated PCa|NT DMRs chr18 20910586 20945671 0.00046742 −46.10978836 Hypo-methylated PCa|NT DMRs chr18 21538184 215382790.005968871 −56.72380952 Hypo-methylated PCa|NT DMRs chr18 2427635624276514 0.000205174 −55.82738095 Hypo-methylated PCa|NT DMRs chr1825228330 25253283 8.96E−05 −29.74484127 Hypo-methylated PCa|NT DMRschr18 27932428 28466836 1.45E−22 −34.74115646 Hypo-methylated PCa|NTDMRs chr18 28620847 28622543 3.99E−07 30.00595238 Hyper-methylatedPCa|NT DMRs chr18 29077638 29077795 9.90E−08 34.74489796Hyper-methylated PCa|NT DMRs chr18 30352209 30352557 1.17E−0526.52089947 Hyper-methylated PCa|NT DMRs chr18 30442296 305095212.29E−06 −22.46580087 Hypo-methylated PCa|NT DMRs chr18 3132333931390167 0.003448944 −32.72176871 Hypo-methylated PCa|NT DMRs chr1831390368 31400593 8.49E−05 20.85460317 Hyper-methylated PCa|NT DMRschr18 32792152 32813276 0.001012507 −23.67518797 Hypo-methylated PCa|NTDMRs chr18 32847409 32851161 0.0005791  28.64173669 Hyper-methylatedPCa|NT DMRs chr18 34020215 34020487 0.002585277 29.01488095Hyper-methylated PCa|NT DMRs chr18 34252375 34274307 0.007428376−31.61794872 Hypo-methylated PCa|NT DMRs chr18 34940110 349424440.001969641 27.85142857 Hyper-methylated PCa|NT DMRs chr18 3539469635608880 4.84E−06 −29.72312925 Hypo-methylated PCa|NT DMRs chr1838126083 38360861 4.90E−08 −28.0805383 Hypo-methylated PCa|NT DMRs chr1838443201 38446621 0.001969641 −27.76587302 Hypo-methylated PCa|NT DMRschr18 42205310 42205381 0.005968871 24.84285714 Hyper-methylated PCa|NTDMRs chr18 42260979 42261339 5.84E−05 36.83690476 Hyper-methylatedPCa|NT DMRs chr18 43729751 43729860 0.005968871 39.48952381Hyper-methylated PCa|NT DMRs chr18 44000356 44007468 0.001969641−20.61768707 Hypo-methylated PCa|NT DMRs chr18 44083744 441192339.63E−06 −23.72040816 Hypo-methylated PCa|NT DMRs chr18 4505274845088031 1.12E−05 27.18872692 Hyper-methylated PCa|NT DMRs chr1845663439 45664546 2.25E−06 22.96245421 Hyper-methylated PCa|NT DMRschr18 45885472 45902852 0.007679542 23.14285714 Hyper-methylated PCa|NTDMRs chr18 45967896 45968273 6.92E−09 35.71652661 Hyper-methylatedPCa|NT DMRs chr18 46140263 46142694 0.000279943 −40.35714286Hypo-methylated PCa|NT DMRs chr18 46269517 46277092 0.00551366126.04081633 Hyper-methylated PCa|NT DMRs chr18 46298127 462982522.86E−05 55.07875458 Hyper-methylated PCa|NT DMRs chr18 4630755846307907 8.29E−07 39.23809524 Hyper-methylated PCa|NT DMRs chr1846378023 46378134 6.42E−05 44.83280423 Hyper-methylated PCa|NT DMRschr18 46423165 46428480 0.002346655 33.04952381 Hyper-methylated PCa|NTDMRs chr18 46449021 46453935 0.000900958 25.91011905 Hyper-methylatedPCa|NT DMRs chr18 46469134 46474220 0.00248539  −27.05952381Hypo-methylated PCa|NT DMRs chr18 46989638 46989709 0.003622801−37.3015873 Hypo-methylated PCa|NT DMRs chr18 47655124 476554280.002585277 −22.03869048 Hypo-methylated PCa|NT DMRs chr18 4780895047809166 0.000205174 −56.75 Hypo-methylated PCa|NT DMRs chr18 4782511547825150 3.32E−06 30.00992063 Hyper-methylated PCa|NT DMRs chr1847926679 47927797 0.000516919 21.6280112 Hyper-methylated PCa|NT DMRschr18 55020895 55020977 6.29E−05 21.37678571 Hyper-methylated PCa|NTDMRs chr18 55103505 55104185 6.07E−15 28.77847619 Hyper-methylatedPCa|NT DMRs chr18 55862725 55862837 0.003949155 25.6547619Hyper-methylated PCa|NT DMRs chr18 55866457 55888853 8.96E−05 −34.6Hypo-methylated PCa|NT DMRs chr18 55914971 55983264 9.19E−17−33.72566586 Hypo-methylated PCa|NT DMRs chr18 56435928 564594910.000916248 −30.58809524 Hypo-methylated PCa|NT DMRs chr18 5653482656534925 0.005513661 −21.73809524 Hypo-methylated PCa|NT DMRs chr1859221458 59221582 4.96E−06 24.05970696 Hyper-methylated PCa|NT DMRschr18 60283708 60284081 4.96E−06 −22.99157509 Hypo-methylated PCa|NTDMRs chr18 60805457 60805774 0.001969641 52.49206349 Hyper-methylatedPCa|NT DMRs chr18 60872466 60874723 0.000836132 −30.16137566Hypo-methylated PCa|NT DMRs chr18 61693760 62049292 2.63E−07−28.17708333 Hypo-methylated PCa|NT DMRs chr18 62341460 623887350.001480644 −25.30666667 Hypo-methylated PCa|NT DMRs chr18 6279999663051094 7.75E−09 −32.64039409 Hypo-methylated PCa|NT DMRs chr1863941738 64696309 7.64E−25 −32.02869048 Hypo-methylated PCa|NT DMRschr18 65397856 65409883 3.75E−05 −23.05039683 Hypo-methylated PCa|NTDMRs chr18 66398373 67055347 4.72E−13 −32.81855159 Hypo-methylatedPCa|NT DMRs chr18 68235017 68584210 8.86E−12 −35.13515406Hypo-methylated PCa|NT DMRs chr18 68695627 69162967 1.50E−24−32.88127706 Hypo-methylated PCa|NT DMRs chr18 71864931 718652390.00023371  −38.9 Hypo-methylated PCa|NT DMRs chr18 72191913 721919820.000205174 37.44047619 Hyper-methylated PCa|NT DMRs chr18 7284339172845789 1.25E−05 −39.57518797 Hypo-methylated PCa|NT DMRs chr1873103349 73103490 0.005968871 32.84285714 Hyper-methylated PCa|NT DMRschr18 73147711 73147792 0.001969641 −22.23809524 Hypo-methylated PCa|NTDMRs chr18 73207047 73263168 1.70E−09 −29.72380952 Hypo-methylatedPCa|NT DMRs chr18 74060619 74063016 1.89E−10 −25.09663866Hypo-methylated PCa|NT DMRs chr18 74100758 74101207 0.00023371 −27.97619048 Hypo-methylated PCa|NT DMRs chr18 74101933 741021080.001969641 30.83333333 Hyper-methylated PCa|NT DMRs chr18 7410260974102752 0.000205174 −32.39285714 Hypo-methylated PCa|NT DMRs chr1874156220 74161241 0.007560755 −25.3025974 Hypo-methylated PCa|NT DMRschr18 74168557 74171800 0.000340264 −24.03184524 Hypo-methylated PCa|NTDMRs chr18 74177635 74178207 6.42E−05 −33.87037037 Hypo-methylatedPCa|NT DMRs chr18 74237436 74240997 0.001789867 −26.85978836Hypo-methylated PCa|NT DMRs chr18 74260396 74271539 1.44E−08−30.62807018 Hypo-methylated PCa|NT DMRs chr18 74302669 743298046.67E−10 −35.3997558 Hypo-methylated PCa|NT DMRs chr18 74359525 744203643.26E−18 −31.78115359 Hypo-methylated PCa|NT DMRs chr18 7445175774471188 8.31E−07 −26.08596491 Hypo-methylated PCa|NT DMRs chr1874485103 74489301 0.00023371  −32.27857143 Hypo-methylated PCa|NT DMRschr18 74501062 74505197 6.96E−08 −26.53602484 Hypo-methylated PCa|NTDMRs chr18 74532349 74532765 5.52E−05 −34.10544218 Hypo-methylatedPCa|NT DMRs chr18 74639935 74668181 0.000187876 −35.94571429Hypo-methylated PCa|NT DMRs chr18 74717117 74718685 0.00097031728.72005013 Hyper-methylated PCa|NT DMRs chr18 74764569 747701860.002802996 25.23558201 Hyper-methylated PCa|NT DMRs chr18 7481153274831307 1.73E−05 39.09942857 Hyper-methylated PCa|NT DMRs chr1874845689 74846836 0.000279449 36.77838828 Hyper-methylated PCa|NT DMRschr18 74974925 75361403 4.84E−35 −33.00436782 Hypo-methylated PCa|NTDMRs chr18 75988277 75989287 2.34E−06 −25.54209524 Hypo-methylatedPCa|NT DMRs chr18 76001773 76066502 4.25E−12 −40.5877551 Hypo-methylatedPCa|NT DMRs chr18 76397834 76398344 1.32E−11 −23.85030525Hypo-methylated PCa|NT DMRs chr18 76686037 76694294 7.83E−12−29.80888031 Hypo-methylated PCa|NT DMRs chr18 76696627 767014021.76E−06 −35.34444444 Hypo-methylated PCa|NT DMRs chr18 7673273776733245 0.000847246 21.2514881 Hyper-methylated PCa|NT DMRs chr1876771436 76771765 0.000377317 −33.36607143 Hypo-methylated PCa|NT DMRschr18 76809069 76819347 0.004095673 −23.38015873 Hypo-methylated PCa|NTDMRs chr18 77164214 77164402 0.00068166  −33.29464286 Hypo-methylatedPCa|NT DMRs chr18 77165070 77166405 0.006962527 24.77922078Hyper-methylated PCa|NT DMRs chr18 77230973 77231391 2.86E−05−26.37728938 Hypo-methylated PCa|NT DMRs chr18 77269146 772711550.005250907 24.71428571 Hyper-methylated PCa|NT DMRs chr18 7728619677286514 0.000138104 −40.89010989 Hypo-methylated PCa|NT DMRs chr1877286792 77286863 0.005968871 45.05714286 Hyper-methylated PCa|NT DMRschr18 77305815 77306020 0.000111427 31.64285714 Hyper-methylated PCa|NTDMRs chr18 77326996 77327149 0.000840726 25.54497354 Hyper-methylatedPCa|NT DMRs chr18 77377287 77378031 2.28E−10 31.24540421Hyper-methylated PCa|NT DMRs chr18 77385419 77385522 0.00011769944.78268398 Hyper-methylated PCa|NT DMRs chr18 77397396 773985526.37E−17 29.2531746 Hyper-methylated PCa|NT DMRs chr18 77401928 774036669.63E−06 24.98503401 Hyper-methylated PCa|NT DMRs chr18 7741705877421389 9.82E−05 −37.43785714 Hypo-methylated PCa|NT DMRs chr1877513564 77513610 0.003622801 30.06349206 Hyper-methylated PCa|NT DMRschr18 77550113 77552761 5.52E−05 40.15612245 Hyper-methylated PCa|NTDMRs chr18 77585927 77587079 0.001387751 21.38888889 Hyper-methylatedPCa|NT DMRs chr18 77624182 77624643 0.001419801 −22.89801587Hypo-methylated PCa|NT DMRs chr18 77645189 77645464 2.86E−05−33.14652015 Hypo-methylated PCa|NT DMRs chr18 77701958 777021300.005968871 −46.71428571 Hypo-methylated PCa|NT DMRs chr18 7774920177749269 0.00068166  −25.5297619 Hypo-methylated PCa|NT DMRs chr1877917521 77918406 1.35E−10 22.29748918 Hyper-methylated PCa|NT DMRschr19 371152 378497 2.00E−06 −23.41666667 Hypo-methylated PCa|NT DMRschr19 378512 384409 0.000836113 21.26478405 Hyper-methylated PCa|NT DMRschr19 402190 405795 0.001255204 −21.92883598 Hypo-methylated PCa|NT DMRschr19 408140 408687 1.88E−05 29.99333333 Hyper-methylated PCa|NT DMRschr19 447294 448407 7.67E−06 20.92712843 Hyper-methylated PCa|NT DMRschr19 478295 478505 0.000413298 −23.54761905 Hypo-methylated PCa|NT DMRschr19 510096 512297 0.002614618 30.35238095 Hyper-methylated PCa|NT DMRschr19 518100 519234 1.10E−15 24.23426704 Hyper-methylated PCa|NT DMRschr19 530194 530751 0.002534928 −34.85714286 Hypo-methylated PCa|NT DMRschr19 548955 551325 0.000267776 −22.86434379 Hypo-methylated PCa|NT DMRschr19 560234 560348 0.000481535 46.91005291 Hyper-methylated PCa|NT DMRschr19 584816 584981 1.76E−06 −26.36309524 Hypo-methylated PCa|NT DMRschr19 601919 602003 0.000205174 −28.57142857 Hypo-methylated PCa|NT DMRschr19 681323 681990 4.33E−08 43.19092262 Hyper-methylated PCa|NT DMRschr19 695352 696175 1.11E−05 33.18673469 Hyper-methylated PCa|NT DMRschr19 709640 710259 5.77E−08 22.90509031 Hyper-methylated PCa|NT DMRschr19 718532 725613 1.48E−18 22.54185185 Hyper-methylated PCa|NT DMRschr19 728020 728703 6.09E−07 29.52857143 Hyper-methylated PCa|NT DMRschr19 757465 757591 0.001181579 28.84013605 Hyper-methylated PCa|NT DMRschr19 782402 783442 8.88E−07 −38.90142857 Hypo-methylated PCa|NT DMRschr19 799341 803541 2.67E−05 −31.15526316 Hypo-methylated PCa|NT DMRschr19 822785 825238 1.37E−06 31.03061224 Hyper-methylated PCa|NT DMRschr19 827950 831864 2.05E−11 27.48715986 Hyper-methylated PCa|NT DMRschr19 835599 836772 0.00046638  33.76785714 Hyper-methylated PCa|NT DMRschr19 839383 841111 1.21E−07 34.06371882 Hyper-methylated PCa|NT DMRschr19 846101 846650 0.008581782 20.56626984 Hyper-methylated PCa|NT DMRschr19 854165 855286 0.00641359  26.8531746 Hyper-methylated PCa|NT DMRschr19 859395 859606 0.0019106  29.60912698 Hyper-methylated PCa|NT DMRschr19 932153 933525 3.00E−10 38.27777778 Hyper-methylated PCa|NT DMRschr19 947398 949464 4.49E−10 32.19115646 Hyper-methylated PCa|NT DMRschr19 1007773 1007858 0.00023371  −25.44155844 Hypo-methylated PCa|NTDMRs chr19 1018844 1019992 0.000358233 −25.04195011 Hypo-methylatedPCa|NT DMRs chr19 1034196 1039775 6.42E−05 25.3923436 Hyper-methylatedPCa|NT DMRs chr19 1067618 1069625 2.77E−06 35.63080357 Hyper-methylatedPCa|NT DMRs chr19 1070598 1071921 2.08E−23 −47.11936937 Hypo-methylatedPCa|NT DMRs chr19 1075175 1075599 0.003622801 −29.02380952Hypo-methylated PCa|NT DMRs chr19 1086852 1088697 0.00102187830.52063492 Hyper-methylated PCa|NT DMRs chr19 1101810 11021020.000480383 48.91798942 Hyper-methylated PCa|NT DMRs chr19 11363081136738 2.06E−05 29.54428571 Hyper-methylated PCa|NT DMRs chr19 11599851160266 0.000239173 23.00250627 Hyper-methylated PCa|NT DMRs chr191161048 1162181 0.006589535 −31.86190476 Hypo-methylated PCa|NT DMRschr19 1176597 1177816 7.21E−08 28.76904762 Hyper-methylated PCa|NT DMRschr19 1242192 1243429 4.02E−06 −29.53586626 Hypo-methylated PCa|NT DMRschr19 1262222 1262382 0.007959104 −23.22108844 Hypo-methylated PCa|NTDMRs chr19 1265942 1266420 1.09E−07 23.61591479 Hyper-methylated PCa|NTDMRs chr19 1271418 1273576 9.86E−11 −40.40735931 Hypo-methylated PCa|NTDMRs chr19 1274244 1275277 4.01E−05 −32.19595238 Hypo-methylated PCa|NTDMRs chr19 1285212 1285734 8.99E−07 22.62380952 Hyper-methylated PCa|NTDMRs chr19 1287464 1288163 9.85E−10 31.49880952 Hyper-methylated PCa|NTDMRs chr19 1288639 1289667 1.10E−06 −38.79276896 Hypo-methylated PCa|NTDMRs chr19 1313033 1313733 3.52E−06 −38.08110119 Hypo-methylated PCa|NTDMRs chr19 1361935 1365290 1.62E−05 43.31690476 Hyper-methylated PCa|NTDMRs chr19 1402314 1403326 2.02E−05 33.21329365 Hyper-methylated PCa|NTDMRs chr19 1406473 1406675 0.003034084 −28.2829932 Hypo-methylatedPCa|NT DMRs chr19 1409232 1413512 2.03E−06 −25.5335277 Hypo-methylatedPCa|NT DMRs chr19 1423630 1423980 6.15E−05 32.34693878 Hyper-methylatedPCa|NT DMRs chr19 1428919 1430074 3.09E−13 −24.95111759 Hypo-methylatedPCa|NT DMRs chr19 1439387 1442204 3.11E−06 −36.11198157 Hypo-methylatedPCa|NT DMRs chr19 1444782 1445172 0.000832876 21.55734127Hyper-methylated PCa|NT DMRs chr19 1465543 1468222 8.35E−36 23.71452888Hyper-methylated PCa|NT DMRs chr19 1488871 1489961 0.00191773425.87900433 Hyper-methylated PCa|NT DMRs chr19 1560401 15604830.005513661 31.65178571 Hyper-methylated PCa|NT DMRs chr19 15664591567001 6.62E−07 −22.68571429 Hypo-methylated PCa|NT DMRs chr19 16088011609277 1.97E−05 46.47714286 Hyper-methylated PCa|NT DMRs chr19 16506861651372 1.18E−05 26.80333333 Hyper-methylated PCa|NT DMRs chr19 18076471807781 0.001969641 −47.3015873 Hypo-methylated PCa|NT DMRs chr191851350 1852902 5.20E−05 26.40445469 Hyper-methylated PCa|NT DMRs chr191871300 1871440 0.004095673 −55.8531746 Hypo-methylated PCa|NT DMRschr19 1873159 1873842 2.86E−06 −42.75062657 Hypo-methylated PCa|NT DMRschr19 1895160 1896611 0.002572399 42.63003663 Hyper-methylated PCa|NTDMRs chr19 1902083 1902433 0.001969641 33.24285714 Hyper-methylatedPCa|NT DMRs chr19 1909735 1910292 0.001036892 23.48049887Hyper-methylated PCa|NT DMRs chr19 1942876 1943965 0.00472248920.05161905 Hyper-methylated PCa|NT DMRs chr19 1966065 1967497 2.11E−0520.50414079 Hyper-methylated PCa|NT DMRs chr19 2039373 2040317 1.44E−05−20.46571429 Hypo-methylated PCa|NT DMRs chr19 2042730 2048391 6.14E−06−22.88179272 Hypo-methylated PCa|NT DMRs chr19 2187846 21880960.000481535 47.99470899 Hyper-methylated PCa|NT DMRs chr19 22822302282727 2.65E−07 37.35862069 Hyper-methylated PCa|NT DMRs chr19 22878242289683 1.32E−06 30.80083333 Hyper-methylated PCa|NT DMRs chr19 22910202293774 1.66E−23 −29.37114846 Hypo-methylated PCa|NT DMRs chr19 23023072303568 4.49E−13 36.91047619 Hyper-methylated PCa|NT DMRs chr19 23454912345665 0.00641359  28.88095238 Hyper-methylated PCa|NT DMRs chr192354910 2359677 0.002529619 −22.81648352 Hypo-methylated PCa|NT DMRschr19 2385087 2390403 0.004164881 −23.08902692 Hypo-methylated PCa|NTDMRs chr19 2424058 2424686 7.04E−12 28.32987013 Hyper-methylated PCa|NTDMRs chr19 2459860 2460148 0.004175963 37.89380952 Hyper-methylatedPCa|NT DMRs chr19 2485702 2489206 1.35E−07 28.4218845 Hyper-methylatedPCa|NT DMRs chr19 2556146 2556599 0.001907648 24.51190476Hyper-methylated PCa|NT DMRs chr19 2560196 2567879 9.55E−05 34.53601954Hyper-methylated PCa|NT DMRs chr19 2588128 2588480 0.00064571 −59.65510204 Hypo-methylated PCa|NT DMRs chr19 2602607 26034320.001651948 −44.16428571 Hypo-methylated PCa|NT DMRs chr19 26166952622934 8.64E−11 29.11208113 Hyper-methylated PCa|NT DMRs chr19 27747752777106 0.003325063 22.76482335 Hyper-methylated PCa|NT DMRs chr192951723 2953384 0.009050681 −36.64761905 Hypo-methylated PCa|NT DMRschr19 2987049 2987498 0.000320955 23.11904762 Hyper-methylated PCa|NTDMRs chr19 3012871 3013791 5.77E−05 −29.91792717 Hypo-methylated PCa|NTDMRs chr19 3138355 3146717 2.37E−05 30.29365079 Hyper-methylated PCa|NTDMRs chr19 3178378 3180413 7.37E−21 53.68178382 Hyper-methylated PCa|NTDMRs chr19 3187917 3190958 1.22E−07 23.74834055 Hyper-methylated PCa|NTDMRs chr19 3238074 3252530 1.09E−12 −26.23852814 Hypo-methylated PCa|NTDMRs chr19 3264014 3269456 3.67E−06 −30.29619048 Hypo-methylated PCa|NTDMRs chr19 3313259 3314118 2.09E−05 −27.2032381 Hypo-methylated PCa|NTDMRs chr19 3317793 3327553 0.000348785 −21.34313725 Hypo-methylatedPCa|NT DMRs chr19 3358286 3358744 1.75E−11 29.22453102 Hyper-methylatedPCa|NT DMRs chr19 3374732 3376007 9.81E−08 −37.57744361 Hypo-methylatedPCa|NT DMRs chr19 3381483 3383444 2.64E−14 −42.01149068 Hypo-methylatedPCa|NT DMRs chr19 3428520 3428833 3.00E−05 28.23469388 Hyper-methylatedPCa|NT DMRs chr19 3478582 3480252 0.005438982 29.71428571Hyper-methylated PCa|NT DMRs chr19 3482628 3483658 3.33E−16 −49.66025267Hypo-methylated PCa|NT DMRs chr19 3511710 3512025 0.000632596−32.56926407 Hypo-methylated PCa|NT DMRs chr19 3516500 35169330.008649834 −20.1625 Hypo-methylated PCa|NT DMRs chr19 3574382 35745122.81E−09 −41.76648352 Hypo-methylated PCa|NT DMRs chr19 3604804 36052484.45E−08 54.52857143 Hyper-methylated PCa|NT DMRs chr19 3607029 36087893.27E−05 20.22236025 Hyper-methylated PCa|NT DMRs chr19 3617535 36181766.63E−09 45.16007326 Hyper-methylated PCa|NT DMRs chr19 3670411 36736832.66E−06 26.97888889 Hyper-methylated PCa|NT DMRs chr19 3683811 36840360.000652115 32.53516484 Hyper-methylated PCa|NT DMRs chr19 37102123710355 0.001583613 −40.88961039 Hypo-methylated PCa|NT DMRs chr193718829 3718907 0.000215808 −31.73015873 Hypo-methylated PCa|NT DMRschr19 3807390 3809019 8.19E−05 −30.504329 Hypo-methylated PCa|NT DMRschr19 3819013 3819252 1.88E−05 −21.65449735 Hypo-methylated PCa|NT DMRschr19 3907690 3908173 6.90E−07 −22.52321429 Hypo-methylated PCa|NT DMRschr19 3948043 3951920 9.11E−06 35.28941799 Hyper-methylated PCa|NT DMRschr19 3966265 3967186 1.12E−07 −29.73219048 Hypo-methylated PCa|NT DMRschr19 3977640 3978160 3.33E−11 −31.31529582 Hypo-methylated PCa|NT DMRschr19 3979239 3979393 0.008482405 −21.01809524 Hypo-methylated PCa|NTDMRs chr19 3981115 3983190 6.42E−05 −35.31534392 Hypo-methylated PCa|NTDMRs chr19 4015736 4015812 0.003622801 22.84920635 Hyper-methylatedPCa|NT DMRs chr19 4038770 4045696 2.08E−10 −32.49554044 Hypo-methylatedPCa|NT DMRs chr19 4046926 4046984 0.001181579 −24.55102041Hypo-methylated PCa|NT DMRs chr19 4058067 4058586 0.00265128621.59693878 Hyper-methylated PCa|NT DMRs chr19 4068070 40687510.000679335 22.80304762 Hyper-methylated PCa|NT DMRs chr19 40864554086794 0.00010418  −34.80986395 Hypo-methylated PCa|NT DMRs chr194103193 4103246 0.00064571  30.16462585 Hyper-methylated PCa|NT DMRschr19 4108812 4109207 6.94E−06 59.03555556 Hyper-methylated PCa|NT DMRschr19 4163482 4168379 0.001394173 −28.98231293 Hypo-methylated PCa|NTDMRs chr19 4198205 4198602 7.28E−11 21.66383929 Hyper-methylated PCa|NTDMRs chr19 4301832 4302494 0.00064571  55.40816327 Hyper-methylatedPCa|NT DMRs chr19 4344571 4344619 0.008482405 52.83809524Hyper-methylated PCa|NT DMRs chr19 4369323 4370878 4.58E−07 23.83088023Hyper-methylated PCa|NT DMRs chr19 4373772 4374700 7.28E−07 35.05639098Hyper-methylated PCa|NT DMRs chr19 4518533 4518598 0.000305995−26.86190476 Hypo-methylated PCa|NT DMRs chr19 4536655 45382640.000524456 −28.80995671 Hypo-methylated PCa|NT DMRs chr19 45426024544477 5.88E−25 38.73634322 Hyper-methylated PCa|NT DMRs chr19 45561614558124 0.000348677 −24.39103641 Hypo-methylated PCa|NT DMRs chr194559566 4559839 0.004095673 50.1 Hyper-methylated PCa|NT DMRs chr194567138 4567482 3.00E−05 −46.75102041 Hypo-methylated PCa|NT DMRs chr194620229 4624238 5.52E−05 −38.80519481 Hypo-methylated PCa|NT DMRs chr194713714 4717697 2.28E−08 −45.64262485 Hypo-methylated PCa|NT DMRs chr194772470 4787253 0.001969641 −25.25833333 Hypo-methylated PCa|NT DMRschr19 4800720 4804755 0.000957967 −31.95362319 Hypo-methylated PCa|NTDMRs chr19 4807778 4808386 0.001344447 43.01785714 Hyper-methylatedPCa|NT DMRs chr19 4877969 4878424 9.61E−05 −39.47767857 Hypo-methylatedPCa|NT DMRs chr19 4878461 4878713 0.000377317 36.97916667Hyper-methylated PCa|NT DMRs chr19 4950551 4950963 0.00011212342.05357143 Hyper-methylated PCa|NT DMRs chr19 5046482 5048428 3.62E−05−24.28611111 Hypo-methylated PCa|NT DMRs chr19 5074460 50753770.003762238 21.56666667 Hyper-methylated PCa|NT DMRs chr19 51304675131295 8.94E−07 34.0377551 Hyper-methylated PCa|NT DMRs chr19 51393475139556 0.000480383 42.31534392 Hyper-methylated PCa|NT DMRs chr195205514 5205583 0.00064571  26.36734694 Hyper-methylated PCa|NT DMRschr19 5215656 5218706 0.003919956 20.71596639 Hyper-methylated PCa|NTDMRs chr19 5250114 5251558 3.44E−06 −38.2452381 Hypo-methylated PCa|NTDMRs chr19 5269515 5269626 0.001969641 −52.9047619 Hypo-methylatedPCa|NT DMRs chr19 5294036 5294417 2.40E−05 23.62698413 Hyper-methylatedPCa|NT DMRs chr19 5322403 5322661 0.000145171 32.5085034Hyper-methylated PCa|NT DMRs chr19 5335747 5339130 1.03E−06 37.4046332Hyper-methylated PCa|NT DMRs chr19 5418110 5426591 0.002185514−25.8218254 Hypo-methylated PCa|NT DMRs chr19 5448575 54506240.00064571  −37.08163265 Hypo-methylated PCa|NT DMRs chr19 54990965499475 0.001969641 36.84126984 Hyper-methylated PCa|NT DMRs chr195621525 5621773 0.000974795 −35.85714286 Hypo-methylated PCa|NT DMRschr19 5686442 5686569 0.007959104 34.59251701 Hyper-methylated PCa|NTDMRs chr19 5838153 5839226 0.008506146 28.1025641 Hyper-methylatedPCa|NT DMRs chr19 5894674 5894896 1.34E−05 25.06870748 Hyper-methylatedPCa|NT DMRs chr19 5905591 5905798 0.005186056 −33.45714286Hypo-methylated PCa|NT DMRs chr19 5914451 5916316 6.65E−06 −29.42031746Hypo-methylated PCa|NT DMRs chr19 5945815 5953965 0.00409567335.83630952 Hyper-methylated PCa|NT DMRs chr19 6114636 61146900.005968871 −25.49809524 Hypo-methylated PCa|NT DMRs chr19 61290556137081 0.00051204  −34.82857143 Hypo-methylated PCa|NT DMRs chr196144622 6154136 2.86E−05 −21.93003663 Hypo-methylated PCa|NT DMRs chr196270202 6273136 1.92E−05 −21.07518797 Hypo-methylated PCa|NT DMRs chr196333548 6333658 0.00068166  −46.35714286 Hypo-methylated PCa|NT DMRschr19 6376545 6378720 5.52E−05 −20.75324675 Hypo-methylated PCa|NT DMRschr19 6417812 6418059 0.000205174 −33.16845238 Hypo-methylated PCa|NTDMRs chr19 6481647 6481833 0.000205174 27.04940476 Hyper-methylatedPCa|NT DMRs chr19 6697435 6697472 0.005968871 50.57142857Hyper-methylated PCa|NT DMRs chr19 6710805 6711076 0.00090825721.97985348 Hyper-methylated PCa|NT DMRs chr19 6724750 6730808 9.82E−07−26.81987578 Hypo-methylated PCa|NT DMRs chr19 6744609 6750343 5.76E−05−35.18492063 Hypo-methylated PCa|NT DMRs chr19 7101062 71016280.001115302 −42.13392857 Hypo-methylated PCa|NT DMRs chr19 72547677266253 0.001969641 −37.21825397 Hypo-methylated PCa|NT DMRs chr197267671 7267734 6.42E−05 −32.65343915 Hypo-methylated PCa|NT DMRs chr197543280 7543862 4.37E−05 −37.94957983 Hypo-methylated PCa|NT DMRs chr197547753 7549196 0.008482405 24.77777778 Hyper-methylated PCa|NT DMRschr19 7592700 7592858 0.001969641 43.54421769 Hyper-methylated PCa|NTDMRs chr19 7615579 7616039 0.000226704 −22.12698413 Hypo-methylatedPCa|NT DMRs chr19 7709745 7711614 1.57E−06 24.61904762 Hyper-methylatedPCa|NT DMRs chr19 7727512 7729091 0.004649531 −30.53673469Hypo-methylated PCa|NT DMRs chr19 7733401 7734144 0.00090934732.19047619 Hyper-methylated PCa|NT DMRs chr19 7796262 78107670.000145907 −23.63214286 Hypo-methylated PCa|NT DMRs chr19 78705927870720 0.000205174 −30.4827381 Hypo-methylated PCa|NT DMRs chr197918539 7918932 0.000191452 −34.01904762 Hypo-methylated PCa|NT DMRschr19 7959672 7960059 5.87E−05 −30.88541667 Hypo-methylated PCa|NT DMRschr19 7983777 7984641 0.0002059  22.02724868 Hyper-methylated PCa|NTDMRs chr19 8048603 8052184 0.00641359  −24.1631746 Hypo-methylatedPCa|NT DMRs chr19 8212110 8212815 0.007959104 −26.75238095Hypo-methylated PCa|NT DMRs chr19 8285132 8290802 0.001969641−34.3047619 Hypo-methylated PCa|NT DMRs chr19 8347921 83627900.001969641 49.77777778 Hyper-methylated PCa|NT DMRs chr19 84057418405903 0.001969641 34.5952381 Hyper-methylated PCa|NT DMRs chr198407336 8408048 4.06E−11 23.83996265 Hyper-methylated PCa|NT DMRs chr198563629 8568649 5.08E−08 28.72363946 Hyper-methylated PCa|NT DMRs chr198641619 8641790 0.001969641 48.38095238 Hyper-methylated PCa|NT DMRschr19 8648734 8649840 0.000205174 −29.39583333 Hypo-methylated PCa|NTDMRs chr19 8808017 8808271 5.70E−06 −28.68779762 Hypo-methylated PCa|NTDMRs chr19 8850037 8900701 6.09E−06 −33.87468672 Hypo-methylated PCa|NTDMRs chr19 8959595 9094957 2.89E−10 −26.82419825 Hypo-methylated PCa|NTDMRs chr19 9121025 9129101 0.000186125 −24.69863946 Hypo-methylatedPCa|NT DMRs chr19 9193322 9245738 2.11E−06 −27.74807256 Hypo-methylatedPCa|NT DMRs chr19 9324971 9341980 0.000836132 −29.67089947Hypo-methylated PCa|NT DMRs chr19 9594179 9600248 0.000570576−25.46296296 Hypo-methylated PCa|NT DMRs chr19 9811212 98114100.001969641 −41.33333333 Hypo-methylated PCa|NT DMRs chr19 1002394410024122 6.16E−06 27.3141321 Hyper-methylated PCa|NT DMRs chr19 1019752410197962 3.91E−08 33.24055829 Hyper-methylated PCa|NT DMRs chr1910212648 10216685 2.12E−05 32.39880952 Hyper-methylated PCa|NT DMRschr19 10348462 10350007 0.000205174 −20.82738095 Hypo-methylated PCa|NTDMRs chr19 10415932 10416154 0.000205174 38.83333333 Hyper-methylatedPCa|NT DMRs chr19 10427154 10427523 0.000680799 −23.62619048Hypo-methylated PCa|NT DMRs chr19 10444751 10446562 3.30E−15−40.16089873 Hypo-methylated PCa|NT DMRs chr19 10621079 106279822.56E−13 34.48672032 Hyper-methylated PCa|NT DMRs chr19 1065517010655622 2.87E−07 −36.90625 Hypo-methylated PCa|NT DMRs chr19 1072828210728944 0.00064571  −41.55646259 Hypo-methylated PCa|NT DMRs chr1910729827 10736595 4.86E−05 −45.60612245 Hypo-methylated PCa|NT DMRschr19 10913426 10916550 0.001775064 33.55357143 Hyper-methylated PCa|NTDMRs chr19 11006529 11008429 0.008576577 −22.41333333 Hypo-methylatedPCa|NT DMRs chr19 11009808 11010367 0.000205174 −52.17857143Hypo-methylated PCa|NT DMRs chr19 11046776 11049788 0.007959104−21.00340136 Hypo-methylated PCa|NT DMRs chr19 11129600 111298580.001969641 −43.06666667 Hypo-methylated PCa|NT DMRs chr19 1122253511225019 0.001115302 −25.075 Hypo-methylated PCa|NT DMRs chr19 1125344511256750 0.000747867 25.72732919 Hyper-methylated PCa|NT DMRs chr1911275865 11276631 0.001083007 −42.96 Hypo-methylated PCa|NT DMRs chr1911290781 11290880 0.00064571  41.2244898 Hyper-methylated PCa|NT DMRschr19 11346278 11346423 0.001969641 −26.88095238 Hypo-methylated PCa|NTDMRs chr19 11510773 11517387 1.37E−06 30.8956044 Hyper-methylated PCa|NTDMRs chr19 11533973 11534787 0.002178049 26.70238095 Hyper-methylatedPCa|NT DMRs chr19 11561958 11563491 0.003764982 −20.23214286Hypo-methylated PCa|NT DMRs chr19 11689380 11695537 7.09E−06 23.63492063Hyper-methylated PCa|NT DMRs chr19 12799867 12801000 1.15E−1039.12310924 Hyper-methylated PCa|NT DMRs chr19 12809953 128101190.005968871 44.51428571 Hyper-methylated PCa|NT DMRs chr19 1286110012863961 7.57E−06 −30.94334975 Hypo-methylated PCa|NT DMRs chr1912991878 12992096 4.45E−06 37.02255639 Hyper-methylated PCa|NT DMRschr19 13024891 13025225 0.001969641 31.39285714 Hyper-methylated PCa|NTDMRs chr19 13135415 13170789 9.28E−07 −22.23027569 Hypo-methylatedPCa|NT DMRs chr19 13187907 13188162 0.009807302 29.96666667Hyper-methylated PCa|NT DMRs chr19 13190529 13192536 0.00795910421.35034014 Hyper-methylated PCa|NT DMRs chr19 13278440 132835796.50E−05 37.99338624 Hyper-methylated PCa|NT DMRs chr19 1331858113319534 4.92E−08 21.4155102 Hyper-methylated PCa|NT DMRs chr19 1333449613338154 3.10E−06 −26.37338936 Hypo-methylated PCa|NT DMRs chr1913354790 13356130 0.00068166  −22.59047619 Hypo-methylated PCa|NT DMRschr19 13378118 13392280 0.000138013 −21.50019841 Hypo-methylated PCa|NTDMRs chr19 13737577 13805027 9.70E−13 −28.52210012 Hypo-methylatedPCa|NT DMRs chr19 13892166 13895619 0.007628253 −32.63265306Hypo-methylated PCa|NT DMRs chr19 13957399 13957836 2.50E−05 30.10204082Hyper-methylated PCa|NT DMRs chr19 13985009 13988520 1.18E−07−40.88280423 Hypo-methylated PCa|NT DMRs chr19 14048637 140495191.25E−05 22.07238095 Hyper-methylated PCa|NT DMRs chr19 1417263714173098 5.49E−06 −34.84117647 Hypo-methylated PCa|NT DMRs chr1914275032 14275847 2.40E−06 −25.12296919 Hypo-methylated PCa|NT DMRschr19 14278533 14278695 0.005968871 36.34285714 Hyper-methylated PCa|NTDMRs chr19 14549802 14551213 0.000215808 49.0984127 Hyper-methylatedPCa|NT DMRs chr19 14590249 14595415 0.000878681 22.97910906Hyper-methylated PCa|NT DMRs chr19 14664087 14664476 0.001060348−33.16796537 Hypo-methylated PCa|NT DMRs chr19 14672903 146734011.05E−06 25.17232143 Hyper-methylated PCa|NT DMRs chr19 1468212914682334 0.009407512 −25.07936508 Hypo-methylated PCa|NT DMRs chr1915093063 15103275 0.001969641 −37.76428571 Hypo-methylated PCa|NT DMRschr19 15362390 15375514 0.001083007 −23.97333333 Hypo-methylated PCa|NTDMRs chr19 15485652 15488971 0.000221601 −35.68 Hypo-methylated PCa|NTDMRs chr19 15574654 15575148 0.001291665 32.36060606 Hyper-methylatedPCa|NT DMRs chr19 15596467 15605638 0.005968871 −38.57142857Hypo-methylated PCa|NT DMRs chr19 16013127 16013383 0.000205174−55.61130952 Hypo-methylated PCa|NT DMRs chr19 16021999 160227673.20E−05 25.27857143 Hyper-methylated PCa|NT DMRs chr19 1617819516179234 2.67E−06 −40.45238095 Hypo-methylated PCa|NT DMRs chr1916240467 16260740 0.00717477  23.69547619 Hyper-methylated PCa|NT DMRschr19 16349971 16350040 0.005968871 42.88571429 Hyper-methylated PCa|NTDMRs chr19 16369475 16370071 2.87E−07 42.40892857 Hyper-methylatedPCa|NT DMRs chr19 16370711 16374643 3.80E−05 29.90895238Hyper-methylated PCa|NT DMRs chr19 16436257 16436488 8.46E−0930.67454844 Hyper-methylated PCa|NT DMRs chr19 16436517 164381181.31E−14 25.92214286 Hyper-methylated PCa|NT DMRs chr19 1646979416474415 1.87E−07 −35.62775041 Hypo-methylated PCa|NT DMRs chr1916553536 16572854 0.003410216 24.22118227 Hyper-methylated PCa|NT DMRschr19 16679409 16681355 6.46E−05 −42.67927171 Hypo-methylated PCa|NTDMRs chr19 16740662 16741101 0.002437742 −25.48677249 Hypo-methylatedPCa|NT DMRs chr19 16997017 16997386 6.42E−05 −52.04444444Hypo-methylated PCa|NT DMRs chr19 16998131 17000172 2.05E−08 32.50805861Hyper-methylated PCa|NT DMRs chr19 17000416 17000553 0.00641359 −35.16666667 Hypo-methylated PCa|NT DMRs chr19 17220811 172231380.000238933 40.76134454 Hyper-methylated PCa|NT DMRs chr19 1729546517295652 5.84E−05 31.91269841 Hyper-methylated PCa|NT DMRs chr1917432633 17434853 7.63E−06 27.89943978 Hyper-methylated PCa|NT DMRschr19 17435675 17435887 2.50E−05 24.71428571 Hyper-methylated PCa|NTDMRs chr19 17436824 17436925 0.008482405 −56.4 Hypo-methylated PCa|NTDMRs chr19 17439195 17444730 1.38E−10 28.28034188 Hyper-methylatedPCa|NT DMRs chr19 17525215 17526515 0.000354065 −24.05291005Hypo-methylated PCa|NT DMRs chr19 17577605 17579893 0.000532147−29.36160714 Hypo-methylated PCa|NT DMRs chr19 17611054 176112764.43E−05 35.53846154 Hyper-methylated PCa|NT DMRs chr19 1775031117754804 0.001241245 −24.24603175 Hypo-methylated PCa|NT DMRs chr1917798795 17799015 0.000260936 20.32857143 Hyper-methylated PCa|NT DMRschr19 17801261 17811490 0.000264944 −25.95914787 Hypo-methylated PCa|NTDMRs chr19 17822460 17826085 0.003314163 −20.30095238 Hypo-methylatedPCa|NT DMRs chr19 17862385 17862689 0.001969641 50.93650794Hyper-methylated PCa|NT DMRs chr19 17865032 17867890 0.002437742−43.73174603 Hypo-methylated PCa|NT DMRs chr19 17889612 178896870.000117699 20.58961039 Hyper-methylated PCa|NT DMRs chr19 1789503717899476 3.50E−07 −35.64130952 Hypo-methylated PCa|NT DMRs chr1917918738 17919098 1.69E−06 40.25378151 Hyper-methylated PCa|NT DMRschr19 17952174 17953860 7.57E−14 −44.66057767 Hypo-methylated PCa|NTDMRs chr19 17956861 17961721 3.70E−07 36.47037037 Hyper-methylatedPCa|NT DMRs chr19 17972294 17972423 0.00064571  −36.07823129Hypo-methylated PCa|NT DMRs chr19 17979885 17981185 0.001836557−37.6014652 Hypo-methylated PCa|NT DMRs chr19 18000442 180162760.000458282 −26.8 Hypo-methylated PCa|NT DMRs chr19 18103747 181055146.67E−08 −37.8452381 Hypo-methylated PCa|NT DMRs chr19 18112564 181138340.000483473 42.45388471 Hyper-methylated PCa|NT DMRs chr19 1816030218164219 1.28E−11 −32.52571429 Hypo-methylated PCa|NT DMRs chr1918241272 18241477 0.005968871 −39.31428571 Hypo-methylated PCa|NT DMRschr19 18280215 18280875 3.45E−06 35.44047619 Hyper-methylated PCa|NTDMRs chr19 18337226 18337259 0.001969641 25.24489796 Hyper-methylatedPCa|NT DMRs chr19 18385724 18389226 0.001076343 −38.34415584Hypo-methylated PCa|NT DMRs chr19 18402128 18402488 0.00466826636.45670996 Hyper-methylated PCa|NT DMRs chr19 18413801 184182590.004147932 22.3572536 Hyper-methylated PCa|NT DMRs chr19 1848735318487402 0.001969641 −37.1 Hypo-methylated PCa|NT DMRs chr19 1849695318497245 0.003314163 −24.89134199 Hypo-methylated PCa|NT DMRs chr1918543841 18546127 4.57E−15 24.48280952 Hyper-methylated PCa|NT DMRschr19 18547391 18548286 7.46E−07 27.42433862 Hyper-methylated PCa|NTDMRs chr19 18575494 18575762 0.004095673 −27.37777778 Hypo-methylatedPCa|NT DMRs chr19 18681567 18681778 0.004095673 −37.64285714Hypo-methylated PCa|NT DMRs chr19 18714318 18716768 8.85E−08 24.22438095Hyper-methylated PCa|NT DMRs chr19 18760599 18761133 3.64E−0934.03669468 Hyper-methylated PCa|NT DMRs chr19 18811957 188121990.000149006 23.7 Hyper-methylated PCa|NT DMRs chr19 18901520 189022844.03E−18 27.05335628 Hyper-methylated PCa|NT DMRs chr19 1890509018906588 0.000374142 38.72380952 Hyper-methylated PCa|NT DMRs chr1918951016 18960412 0.001352148 −25.53112245 Hypo-methylated PCa|NT DMRschr19 18979694 18981748 2.18E−39 39.42739927 Hyper-methylated PCa|NTDMRs chr19 19063548 19063652 0.00064571  21.24489796 Hyper-methylatedPCa|NT DMRs chr19 19147116 19157167 0.000104747 −40.22321429Hypo-methylated PCa|NT DMRs chr19 19271495 19271710 0.00329081738.84464286 Hyper-methylated PCa|NT DMRs chr19 19283026 192830810.003622801 41.43730159 Hyper-methylated PCa|NT DMRs chr19 1949164519492619 0.000118733 −40.93650794 Hypo-methylated PCa|NT DMRs chr1919571532 19572810 0.007904371 26.40505952 Hyper-methylated PCa|NT DMRschr19 19651498 19651882 1.66E−05 21.09943978 Hyper-methylated PCa|NTDMRs chr19 19653211 19654259 0.000214897 37.62783883 Hyper-methylatedPCa|NT DMRs chr19 19778818 19778994 0.000205174 54.33928571Hyper-methylated PCa|NT DMRs chr19 20278004 20278616 1.18E−0830.81845238 Hyper-methylated PCa|NT DMRs chr19 20348686 203492286.93E−06 45.61111111 Hyper-methylated PCa|NT DMRs chr19 2060625020607581 2.15E−07 31.74557823 Hyper-methylated PCa|NT DMRs chr1920843255 20843844 0.001992179 −44.47142857 Hypo-methylated PCa|NT DMRschr19 20847353 20847508 0.005968871 56.88571429 Hyper-methylated PCa|NTDMRs chr19 21623174 21623405 0.000233379 −34.67142857 Hypo-methylatedPCa|NT DMRs chr19 22123798 22181253 0.000377317 −34.11904762Hypo-methylated PCa|NT DMRs chr19 22490402 22550924 5.84E−05−31.26984127 Hypo-methylated PCa|NT DMRs chr19 22802992 228033600.005968871 −40.42857143 Hypo-methylated PCa|NT DMRs chr19 2288607822886440 4.11E−07 −29.15162907 Hypo-methylated PCa|NT DMRs chr1923120722 23159340 0.00023371  −39.27714286 Hypo-methylated PCa|NT DMRschr19 23227552 23245488 0.005968871 −26.84761905 Hypo-methylated PCa|NTDMRs chr19 23432262 23432362 0.001241245 23.78042328 Hyper-methylatedPCa|NT DMRs chr19 28127248 28148388 0.003464153 −27.0995671Hypo-methylated PCa|NT DMRs chr19 30086741 30089433 0.005513661−34.20535714 Hypo-methylated PCa|NT DMRs chr19 30166557 301694470.000176046 −41.88961039 Hypo-methylated PCa|NT DMRs chr19 3094197330942241 1.41E−06 −31.22987013 Hypo-methylated PCa|NT DMRs chr1930986767 30987216 0.00064571  −29.3414966 Hypo-methylated PCa|NT DMRschr19 31321711 31321998 0.001969641 −45.18253968 Hypo-methylated PCa|NTDMRs chr19 31474520 31555683 0.001969641 −23.74285714 Hypo-methylatedPCa|NT DMRs chr19 31826312 31839968 1.18E−09 23.75385488Hyper-methylated PCa|NT DMRs chr19 32714895 32715500 1.88E−0934.75977444 Hyper-methylated PCa|NT DMRs chr19 32801697 328200050.005968871 −20.4 Hypo-methylated PCa|NT DMRs chr19 32898351 328985160.005968871 −50.53714286 Hypo-methylated PCa|NT DMRs chr19 3301413833028623 0.00641359  −25.08174603 Hypo-methylated PCa|NT DMRs chr1933167677 33168890 0.001836557 31 Hyper-methylated PCa|NT DMRs chr1933462065 33462322 0.000145094 −26.91984127 Hypo-methylated PCa|NT DMRschr19 33493262 33494136 0.007560755 −28.73214286 Hypo-methylated PCa|NTDMRs chr19 33528506 33528757 0.00064571  45.38095238 Hyper-methylatedPCa|NT DMRs chr19 33703571 33705583 6.64E−06 −22.44658385Hypo-methylated PCa|NT DMRs chr19 33738253 33740439 1.41E−06 47.6890873Hyper-methylated PCa|NT DMRs chr19 33863333 33863367 0.00196964152.16269841 Hyper-methylated PCa|NT DMRs chr19 34175937 341760920.001969641 −30.52380952 Hypo-methylated PCa|NT DMRs chr19 3419096934191046 0.005968871 −24.62857143 Hypo-methylated PCa|NT DMRs chr1934269364 34270600 0.000159126 −32.30392157 Hypo-methylated PCa|NT DMRschr19 34288917 34289092 0.000397381 28.86813187 Hyper-methylated PCa|NTDMRs chr19 34397576 34398063 2.01E−07 39.61547619 Hyper-methylatedPCa|NT DMRs chr19 34990698 34992342 5.22E−06 27.00620491Hyper-methylated PCa|NT DMRs chr19 35329641 35330050 2.37E−05 30.0015873Hyper-methylated PCa|NT DMRs chr19 35513606 35514698 0.00418787522.17904762 Hyper-methylated PCa|NT DMRs chr19 35529289 355304836.42E−05 51.38624339 Hyper-methylated PCa|NT DMRs chr19 3557136135571936 0.004505524 −22.72619048 Hypo-methylated PCa|NT DMRs chr1935589653 35589780 0.001969641 −46.29444444 Hypo-methylated PCa|NT DMRschr19 35617536 35622220 4.92E−05 −32.45445135 Hypo-methylated PCa|NTDMRs chr19 35630057 35630425 0.001969641 37.53412698 Hyper-methylatedPCa|NT DMRs chr19 35646137 35646705 3.45E−06 27.78548753Hyper-methylated PCa|NT DMRs chr19 35776898 35786457 1.86E−05−30.05357143 Hypo-methylated PCa|NT DMRs chr19 35786470 357869134.08E−07 43.64172336 Hyper-methylated PCa|NT DMRs chr19 3586706635889791 0.000918789 −34.93373016 Hypo-methylated PCa|NT DMRs chr1936034454 36036245 1.05E−06 20.21031746 Hyper-methylated PCa|NT DMRschr19 36076491 36095407 0.00179283  −27.83333333 Hypo-methylated PCa|NTDMRs chr19 36156676 36162056 0.000106046 −25.38388278 Hypo-methylatedPCa|NT DMRs chr19 36164216 36164312 0.001607793 20.10170068Hyper-methylated PCa|NT DMRs chr19 36247064 36247623 4.08E−05 22.3527619Hyper-methylated PCa|NT DMRs chr19 36288748 36288946 0.00048153525.96825397 Hyper-methylated PCa|NT DMRs chr19 36389354 363895950.00046742  25.23246753 Hyper-methylated PCa|NT DMRs chr19 3642523636426349 0.001969641 −31.25 Hypo-methylated PCa|NT DMRs chr19 3645630836473550 7.18E−06 −27.83460317 Hypo-methylated PCa|NT DMRs chr1936497964 36499748 2.28E−05 −36.21794872 Hypo-methylated PCa|NT DMRschr19 36523147 36526376 8.87E−08 27.75608466 Hyper-methylated PCa|NTDMRs chr19 36623220 36630256 0.002082381 −25.39635854 Hypo-methylatedPCa|NT DMRs chr19 36643236 36645673 2.09E−05 30.6727619 Hyper-methylatedPCa|NT DMRs chr19 36736022 36736839 7.02E−16 34.61350826Hyper-methylated PCa|NT DMRs chr19 37287620 37287787 0.00851153222.78717949 Hyper-methylated PCa|NT DMRs chr19 37719008 377191050.00064571  −40.95918367 Hypo-methylated PCa|NT DMRs chr19 3832189938344642 4.57E−08 −36.26488095 Hypo-methylated PCa|NT DMRs chr1938700251 38705221 1.82E−10 28.42932331 Hyper-methylated PCa|NT DMRschr19 38712862 38713495 5.06E−13 39.16243386 Hyper-methylated PCa|NTDMRs chr19 38734003 38736437 0.00603903  −29.94021164 Hypo-methylatedPCa|NT DMRs chr19 38741729 38742036 0.001451132 −30.25164835Hypo-methylated PCa|NT DMRs chr19 38757037 38768268 0.001115302−38.47321429 Hypo-methylated PCa|NT DMRs chr19 38876420 388780089.21E−18 32.2982962 Hyper-methylated PCa|NT DMRs chr19 39018216 390184372.04E−05 22.04047619 Hyper-methylated PCa|NT DMRs chr19 3908361639105102 4.63E−07 −38.84093407 Hypo-methylated PCa|NT DMRs chr1939227169 39228308 2.23E−08 42.62759104 Hyper-methylated PCa|NT DMRschr19 39260650 39261013 1.18E−08 24.11309524 Hyper-methylated PCa|NTDMRs chr19 39466078 39467011 4.62E−14 23.51975684 Hyper-methylatedPCa|NT DMRs chr19 39523419 39524207 0.000260936 −36.13809524Hypo-methylated PCa|NT DMRs chr19 39694478 39694549 0.00012243220.65800866 Hyper-methylated PCa|NT DMRs chr19 39908574 399086864.32E−05 27.52014652 Hyper-methylated PCa|NT DMRs chr19 3995378939954920 0.001181579 −30.06802721 Hypo-methylated PCa|NT DMRs chr1940009637 40009906 5.84E−05 −26.58333333 Hypo-methylated PCa|NT DMRschr19 40061407 40082871 3.39E−05 −27.90995671 Hypo-methylated PCa|NTDMRs chr19 40264258 40282009 0.000554289 −24.57857143 Hypo-methylatedPCa|NT DMRs chr19 40329675 40329748 6.42E−05 −32.34920635Hypo-methylated PCa|NT DMRs chr19 40366038 40366240 6.22E−05−30.11394558 Hypo-methylated PCa|NT DMRs chr19 40732294 407328043.39E−13 21.29153439 Hyper-methylated PCa|NT DMRs chr19 4087161840871679 2.83E−05 43.18681319 Hyper-methylated PCa|NT DMRs chr1940904509 40904765 1.21E−07 33.95739348 Hyper-methylated PCa|NT DMRschr19 40923191 40923426 0.005968871 48.57619048 Hyper-methylated PCa|NTDMRs chr19 40938664 40939515 0.000474458 −36.24835165 Hypo-methylatedPCa|NT DMRs chr19 41018897 41018956 4.11E−07 21.87218045Hyper-methylated PCa|NT DMRs chr19 41086118 41086527 0.00756075535.04112554 Hyper-methylated PCa|NT DMRs chr19 41119033 411210315.50E−12 40.30868839 Hyper-methylated PCa|NT DMRs chr19 4122340541225006 9.80E−05 −27.86984127 Hypo-methylated PCa|NT DMRs chr1941312763 41313052 0.000149331 37.35324675 Hyper-methylated PCa|NT DMRschr19 41836698 41837087 4.97E−06 −28.87507003 Hypo-methylated PCa|NTDMRs chr19 41843818 41847924 3.67E−06 −22.92404762 Hypo-methylatedPCa|NT DMRs chr19 41897188 41899754 0.009106413 23.71428571Hyper-methylated PCa|NT DMRs chr19 41921972 41927168 0.00033154136.97402597 Hyper-methylated PCa|NT DMRs chr19 41992299 420113617.39E−05 −21.33100775 Hypo-methylated PCa|NT DMRs chr19 4207687742093112 0.003314163 −34.68095238 Hypo-methylated PCa|NT DMRs chr1942419879 42420037 0.005034713 28.85714286 Hyper-methylated PCa|NT DMRschr19 42656558 42667828 0.000339757 −22.83541667 Hypo-methylated PCa|NTDMRs chr19 42703350 42708858 2.21E−10 58.5042471 Hyper-methylated PCa|NTDMRs chr19 42712919 42713576 0.001969641 −48.25396825 Hypo-methylatedPCa|NT DMRs chr19 42785248 42786153 1.42E−05 29.16770186Hyper-methylated PCa|NT DMRs chr19 42927001 42929067 1.85E−1220.34285714 Hyper-methylated PCa|NT DMRs chr19 43430497 435198717.21E−08 −32.48571429 Hypo-methylated PCa|NT DMRs chr19 4360106243690222 1.06E−06 −25.22582973 Hypo-methylated PCa|NT DMRs chr1943715046 43832523 0.00028643  −20.89845938 Hypo-methylated PCa|NT DMRschr19 44111754 44112217 0.000572385 36.7297619 Hyper-methylated PCa|NTDMRs chr19 44313171 44318001 6.98E−05 −28.71938776 Hypo-methylatedPCa|NT DMRs chr19 45033786 45034000 0.000205174 −47.1672619Hypo-methylated PCa|NT DMRs chr19 45260361 45262537 2.78E−12−20.01241956 Hypo-methylated PCa|NT DMRs chr19 45381937 453821130.00064571  −47.97959184 Hypo-methylated PCa|NT DMRs chr19 4544709945447241 0.00023371  47.58809524 Hyper-methylated PCa|NT DMRs chr1945664240 45666026 7.81E−10 −38.21020408 Hypo-methylated PCa|NT DMRschr19 45975735 45976180 0.000914361 23.05102041 Hyper-methylated PCa|NTDMRs chr19 46102734 46102800 0.007628253 28.12244898 Hyper-methylatedPCa|NT DMRs chr19 46386083 46388503 1.35E−08 −35.62518979Hypo-methylated PCa|NT DMRs chr19 46503762 46504395 1.52E−07 42.25340136Hyper-methylated PCa|NT DMRs chr19 46714634 46730048 0.000556997−23.10098522 Hypo-methylated PCa|NT DMRs chr19 46773855 467745470.001241245 32.07936508 Hyper-methylated PCa|NT DMRs chr19 4678706246801217 0.000140031 33.01120448 Hyper-methylated PCa|NT DMRs chr1946877002 46878175 0.009924186 −28.48571429 Hypo-methylated PCa|NT DMRschr19 46907158 46908576 7.08E−14 26.33525836 Hyper-methylated PCa|NTDMRs chr19 47125242 47126400 0.000564835 −26.34238095 Hypo-methylatedPCa|NT DMRs chr19 47128687 47134999 0.002437742 29.9031746Hyper-methylated PCa|NT DMRs chr19 47225733 47226402 0.00346415331.2021645 Hyper-methylated PCa|NT DMRs chr19 47259975 47260133 9.92E−0843.12018141 Hyper-methylated PCa|NT DMRs chr19 47479848 474811770.001969641 −50.03401361 Hypo-methylated PCa|NT DMRs chr19 4750636347508649 4.65E−07 31.4552964 Hyper-methylated PCa|NT DMRs chr19 4759839147598720 0.000118733 36.75396825 Hyper-methylated PCa|NT DMRs chr1947617702 47617860 1.97E−05 −40.87714286 Hypo-methylated PCa|NT DMRschr19 47635083 47635313 0.004677148 −22.4025974 Hypo-methylated PCa|NTDMRs chr19 47730276 47731854 8.96E−18 21.13639456 Hyper-methylatedPCa|NT DMRs chr19 47765721 47765770 0.005968871 40.66666667Hyper-methylated PCa|NT DMRs chr19 47838885 47840511 0.00196964134.65714286 Hyper-methylated PCa|NT DMRs chr19 47879851 478800710.000377317 20.78571429 Hyper-methylated PCa|NT DMRs chr19 4791998047920505 0.000574164 29.75064935 Hyper-methylated PCa|NT DMRs chr1947923347 47924413 0.00641359  33.57301587 Hyper-methylated PCa|NT DMRschr19 48000299 48003854 1.45E−08 −30.01479592 Hypo-methylated PCa|NTDMRs chr19 48025138 48025353 0.005968871 38.4 Hyper-methylated PCa|NTDMRs chr19 48122127 48122640 0.001850915 −46.85119048 Hypo-methylatedPCa|NT DMRs chr19 48267524 48267826 0.000974795 −45.16071429Hypo-methylated PCa|NT DMRs chr19 48565036 48565312 0.000375274−25.3452381 Hypo-methylated PCa|NT DMRs chr19 48588535 485939270.005968871 −52.17142857 Hypo-methylated PCa|NT DMRs chr19 4882835148834221 0.000232923 29.88809524 Hyper-methylated PCa|NT DMRs chr1948993963 48995094 0.000113183 22.20793651 Hyper-methylated PCa|NT DMRschr19 49046770 49047001 0.000481535 −39.65079365 Hypo-methylated PCa|NTDMRs chr19 49055198 49055683 8.35E−08 −42 Hypo-methylated PCa|NT DMRschr19 49116250 49119583 6.45E−16 −39.1979243 Hypo-methylated PCa|NT DMRschr19 49133883 49134291 1.71E−05 24.19025974 Hyper-methylated PCa|NTDMRs chr19 49216218 49216916 0.006170736 22.58333333 Hyper-methylatedPCa|NT DMRs chr19 49232216 49232628 7.26E−10 −27.08435374Hypo-methylated PCa|NT DMRs chr19 49263800 49263986 0.00048153547.02380952 Hyper-methylated PCa|NT DMRs chr19 49275993 492761800.00064571  −57.84353741 Hypo-methylated PCa|NT DMRs chr19 4936280849363161 0.003464153 21.22597403 Hyper-methylated PCa|NT DMRs chr1949363634 49363921 7.35E−05 −30.28126984 Hypo-methylated PCa|NT DMRschr19 49426467 49426594 0.001969641 −37.86904762 Hypo-methylated PCa|NTDMRs chr19 49428602 49428862 0.00641359  −34.36904762 Hypo-methylatedPCa|NT DMRs chr19 49466237 49468076 0.006207271 31.63412698Hyper-methylated PCa|NT DMRs chr19 49564802 49565792 6.21E−0527.87755102 Hyper-methylated PCa|NT DMRs chr19 49568737 495695570.004047992 20.30442177 Hyper-methylated PCa|NT DMRs chr19 4958997649590301 1.76E−06 −49.00912698 Hypo-methylated PCa|NT DMRs chr1949719451 49719808 0.001969641 −39.37063492 Hypo-methylated PCa|NT DMRschr19 49841314 49842964 2.74E−10 −32.92473118 Hypo-methylated PCa|NTDMRs chr19 49918548 49918601 0.000205174 45.42261905 Hyper-methylatedPCa|NT DMRs chr19 49937004 49937224 0.000114755 30.78388278Hyper-methylated PCa|NT DMRs chr19 49939998 49940044 0.00196964123.83333333 Hyper-methylated PCa|NT DMRs chr19 50215887 502167620.00569382  −20.77904762 Hypo-methylated PCa|NT DMRs chr19 5022731750232237 0.001310211 −24.12380952 Hypo-methylated PCa|NT DMRs chr1950312016 50312821 8.02E−10 21.69146141 Hyper-methylated PCa|NT DMRschr19 50363547 50364453 3.66E−05 −48.4952381 Hypo-methylated PCa|NT DMRschr19 50396731 50401450 0.00460588  30.10412698 Hyper-methylated PCa|NTDMRs chr19 50481363 50481764 0.005521663 −24.41904762 Hypo-methylatedPCa|NT DMRs chr19 50706335 50706403 0.004553481 23.05555556Hyper-methylated PCa|NT DMRs chr19 50770354 50770611 0.00022692 26.98095238 Hyper-methylated PCa|NT DMRs chr19 50867971 508680200.008482405 25.05238095 Hyper-methylated PCa|NT DMRs chr19 5092014950921379 0.004516076 −31.59325397 Hypo-methylated PCa|NT DMRs chr1951022642 51022743 5.82E−05 −21.08333333 Hypo-methylated PCa|NT DMRschr19 51340199 51345782 3.93E−05 −34.02209524 Hypo-methylated PCa|NTDMRs chr19 51521769 51523206 4.62E−15 29.45134199 Hyper-methylatedPCa|NT DMRs chr19 51568096 51568561 2.53E−11 24.20767196Hyper-methylated PCa|NT DMRs chr19 52216773 52222059 1.23E−05−20.94513458 Hypo-methylated PCa|NT DMRs chr19 52469725 524893310.005295761 −25.88961039 Hypo-methylated PCa|NT DMRs chr19 5299596252997014 4.00E−08 27.41643991 Hyper-methylated PCa|NT DMRs chr1953540896 53541139 1.69E−06 22.32492997 Hyper-methylated PCa|NT DMRschr19 53777249 53798642 0.005968871 −31.62698413 Hypo-methylated PCa|NTDMRs chr19 54128020 54132209 0.005513661 40.54464286 Hyper-methylatedPCa|NT DMRs chr19 54370619 54370797 0.005633183 23.97959184Hyper-methylated PCa|NT DMRs chr19 54617586 54617655 0.00064571 −25.12244898 Hypo-methylated PCa|NT DMRs chr19 54937160 549436967.74E−06 −27.82822511 Hypo-methylated PCa|NT DMRs chr19 5497205354974086 0.002579925 −25.38551587 Hypo-methylated PCa|NT DMRs chr1955065801 55107691 7.37E−10 −33.14115646 Hypo-methylated PCa|NT DMRschr19 55596179 55599200 2.35E−22 34.57922999 Hyper-methylated PCa|NTDMRs chr19 55609979 55610202 0.001969641 37.14206349 Hyper-methylatedPCa|NT DMRs chr19 55630230 55630699 1.34E−05 38.71428571Hyper-methylated PCa|NT DMRs chr19 55668903 55669229 0.000441963−23.15037594 Hypo-methylated PCa|NT DMRs chr19 55684877 556849503.00E−05 21.59183673 Hyper-methylated PCa|NT DMRs chr19 5568631655689055 0.006207271 −22.7281746 Hypo-methylated PCa|NT DMRs chr1955693469 55698281 6.90E−06 −32.04863946 Hypo-methylated PCa|NT DMRschr19 55708628 55716773 4.41E−05 −21.48095238 Hypo-methylated PCa|NTDMRs chr19 55760770 55768901 3.89E−06 36.77258687 Hyper-methylatedPCa|NT DMRs chr19 55815996 55816145 6.94E−06 −23.15460317Hypo-methylated PCa|NT DMRs chr19 55873668 55874073 0.001139334−24.46388889 Hypo-methylated PCa|NT DMRs chr19 55963619 559644464.51E−06 20.04557823 Hyper-methylated PCa|NT DMRs chr19 5600268456005173 5.51E−05 −20.05481728 Hypo-methylated PCa|NT DMRs chr1956018603 56018762 0.001969641 −32.15873016 Hypo-methylated PCa|NT DMRschr19 56037188 56037287 0.00064571  −30.05442177 Hypo-methylated PCa|NTDMRs chr19 56075713 56075917 1.97E−05 −40.79428571 Hypo-methylatedPCa|NT DMRs chr19 56343833 56347146 3.32E−06 −29.86904762Hypo-methylated PCa|NT DMRs chr19 56608157 56608326 0.000974795−22.77380952 Hypo-methylated PCa|NT DMRs chr19 56608485 566094059.92E−08 −48.2047619 Hypo-methylated PCa|NT DMRs chr19 56612917 566146850.000207488 21.35548654 Hyper-methylated PCa|NT DMRs chr19 5661722356618105 4.08E−06 29.52321429 Hyper-methylated PCa|NT DMRs chr1957356004 57356483 0.007628253 −29.44897959 Hypo-methylated PCa|NT DMRschr19 57375887 57376129 4.43E−05 23.47069597 Hyper-methylated PCa|NTDMRs chr19 58314937 58325339 0.000731086 −26.4984127 Hypo-methylatedPCa|NT DMRs chr19 58520847 58521755 0.000349861 28.92 Hyper-methylatedPCa|NT DMRs chr19 58715677 58715746 0.000909347 25.86507937Hyper-methylated PCa|NT DMRs chr19 58839320 58839436 0.001115302−29.51785714 Hypo-methylated PCa|NT DMRs chr19 58860844 588651650.000166027 −22.52857143 Hypo-methylated PCa|NT DMRs chr19 5890794158910708 2.07E−08 24.83158263 Hyper-methylated PCa|NT DMRs chr1958916382 58916576 0.004266047 −26.55584416 Hypo-methylated PCa|NT DMRschr20 290953 291152 2.85E−05 33.84835165 Hyper-methylated PCa|NT DMRschr20 370829 371257 0.009924186 −25.04867725 Hypo-methylated PCa|NT DMRschr20 398770 401742 1.52E−10 −30.97703081 Hypo-methylated PCa|NT DMRschr20 623281 623336 0.004095673 28.78571429 Hyper-methylated PCa|NT DMRschr20 680838 681383 0.000170278 −41.92738095 Hypo-methylated PCa|NT DMRschr20 1783684 1784552 9.09E−30 23.9414966 Hyper-methylated PCa|NT DMRschr20 1876471 1877094 3.44E−05 35.09448622 Hyper-methylated PCa|NT DMRschr20 1893501 1893587 0.001969641 −35.88095238 Hypo-methylated PCa|NTDMRs chr20 1918171 1926404 0.001098825 20.21288515 Hyper-methylatedPCa|NT DMRs chr20 2510691 2521029 0.000138104 −22.48388278Hypo-methylated PCa|NT DMRs chr20 2655366 2667918 5.42E−05 −30.0015873Hypo-methylated PCa|NT DMRs chr20 2668808 2670350 0.00331416335.17619048 Hyper-methylated PCa|NT DMRs chr20 2729998 2731561 5.89E−0626.17453839 Hyper-methylated PCa|NT DMRs chr20 2781180 2782256 1.02E−0620.14887218 Hyper-methylated PCa|NT DMRs chr20 2801591 2803966 5.73E−1330.34688013 Hyper-methylated PCa|NT DMRs chr20 2852740 28530920.00179283  26.53679654 Hyper-methylated PCa|NT DMRs chr20 30520433052923 9.29E−14 34.21098485 Hyper-methylated PCa|NT DMRs chr20 30638623064520 0.000161254 39.41002506 Hyper-methylated PCa|NT DMRs chr203073286 3075043 2.38E−17 24.93670412 Hyper-methylated PCa|NT DMRs chr203218646 3219205 5.20E−13 35.7965368 Hyper-methylated PCa|NT DMRs chr203220409 3220986 1.64E−15 35.93303571 Hyper-methylated PCa|NT DMRs chr203732490 3733265 3.41E−19 28.77585513 Hyper-methylated PCa|NT DMRs chr205046531 5046645 0.001146289 23.01785714 Hyper-methylated PCa|NT DMRschr20 5641563 5641760 0.005968871 39.82857143 Hyper-methylated PCa|NTDMRs chr20 6160596 6723432 8.08E−12 −32.2335277 Hypo-methylated PCa|NTDMRs chr20 6783939 7969623 1.39E−26 −35.28099048 Hypo-methylated PCa|NTDMRs chr20 10603943 10647944 1.92E−05 −26.14761905 Hypo-methylatedPCa|NT DMRs chr20 11622746 11658545 0.00064571  −31.90544218Hypo-methylated PCa|NT DMRs chr20 11690071 11835274 1.63E−07−32.35930736 Hypo-methylated PCa|NT DMRs chr20 12020714 128734103.95E−18 −32.26139194 Hypo-methylated PCa|NT DMRs chr20 1382876113927899 4.29E−08 −29.45646259 Hypo-methylated PCa|NT DMRs chr2016106790 16287187 0.005438982 −32.06904762 Hypo-methylated PCa|NT DMRschr20 17595189 17595700 1.78E−05 −36.75600907 Hypo-methylated PCa|NTDMRs chr20 17595971 17596423 4.89E−05 30.46369048 Hyper-methylatedPCa|NT DMRs chr20 17598252 17601120 0.003573252 −24.11734694Hypo-methylated PCa|NT DMRs chr20 17844683 17851138 0.005513661−21.2244898 Hypo-methylated PCa|NT DMRs chr20 17936940 179371100.001969641 45.26587302 Hyper-methylated PCa|NT DMRs chr20 1823383918250127 6.98E−05 −23.68367347 Hypo-methylated PCa|NT DMRs chr2018485311 18485580 9.30E−06 −28.17142857 Hypo-methylated PCa|NT DMRschr20 18794791 18818686 8.00E−06 −26.81532091 Hypo-methylated PCa|NTDMRs chr20 19523960 19524213 0.001969641 35.3968254 Hyper-methylatedPCa|NT DMRs chr20 19642546 19669183 0.000836132 −35.53846154Hypo-methylated PCa|NT DMRs chr20 20344717 20348271 1.31E−34 26.1655754Hyper-methylated PCa|NT DMRs chr20 21390540 21442274 0.00641359 −32.02301587 Hypo-methylated PCa|NT DMRs chr20 21497910 214988806.67E−10 26.23809524 Hyper-methylated PCa|NT DMRs chr20 2158917821596682 0.001789867 −39.82539683 Hypo-methylated PCa|NT DMRs chr2021687395 21695629 6.88E−16 24.47631416 Hyper-methylated PCa|NT DMRschr20 22557524 22557992 2.26E−07 21.02063492 Hyper-methylated PCa|NTDMRs chr20 23031774 23032167 0.000481535 21.85714286 Hyper-methylatedPCa|NT DMRs chr20 23066264 23067193 2.17E−11 44.94617605Hyper-methylated PCa|NT DMRs chr20 24318195 24415710 5.24E−06−35.83690476 Hypo-methylated PCa|NT DMRs chr20 24637710 247511081.66E−32 −32.46536797 Hypo-methylated PCa|NT DMRs chr20 2476778724852446 6.16E−21 −37.34133885 Hypo-methylated PCa|NT DMRs chr2024859448 24873322 0.000411983 −26.20922619 Hypo-methylated PCa|NT DMRschr20 24929954 24930149 0.000481535 39.95873016 Hyper-methylated PCa|NTDMRs chr20 25085136 25086082 0.000260936 −23.98952381 Hypo-methylatedPCa|NT DMRs chr20 25128565 25129142 0.002680483 20.00729167Hyper-methylated PCa|NT DMRs chr20 25257915 25258763 0.009924186−28.66666667 Hypo-methylated PCa|NT DMRs chr20 25262245 252627372.50E−05 −31.31972789 Hypo-methylated PCa|NT DMRs chr20 2529076325290885 0.000117699 −38.72727273 Hypo-methylated PCa|NT DMRs chr2026205151 26205219 0.001969641 −31.52619048 Hypo-methylated PCa|NT DMRschr20 26248196 26257114 0.001181579 −35.12244898 Hypo-methylated PCa|NTDMRs chr20 29439365 29439433 0.001969641 −41.6031746 Hypo-methylatedPCa|NT DMRs chr20 29516322 29517183 4.81E−05 −25.87642857Hypo-methylated PCa|NT DMRs chr20 29596137 29596829 0.000570576−25.31206349 Hypo-methylated PCa|NT DMRs chr20 30080173 300945560.005513661 −24.57954145 Hypo-methylated PCa|NT DMRs chr20 3015600230156074 0.00576331  21.44642857 Hyper-methylated PCa|NT DMRs chr2030193523 30193987 1.00E−11 28.17706767 Hyper-methylated PCa|NT DMRschr20 30420016 30422355 0.002767976 −20.62683983 Hypo-methylated PCa|NTDMRs chr20 30639262 30639427 0.000974795 25.98690476 Hyper-methylatedPCa|NT DMRs chr20 30646236 30646860 0.005968871 −28.08571429Hypo-methylated PCa|NT DMRs chr20 30681095 30695433 7.57E−05−27.94444444 Hypo-methylated PCa|NT DMRs chr20 31062364 310634860.001480644 26.39761905 Hyper-methylated PCa|NT DMRs chr20 3116234431162702 0.000179572 25.46845238 Hyper-methylated PCa|NT DMRs chr2031168764 31170864 6.69E−05 28.61986864 Hyper-methylated PCa|NT DMRschr20 31210531 31210734 6.69E−05 −37.28285714 Hypo-methylated PCa|NTDMRs chr20 31261124 31261452 5.84E−05 55.21428571 Hyper-methylatedPCa|NT DMRs chr20 32232529 32239958 1.70E−05 −41.3047619 Hypo-methylatedPCa|NT DMRs chr20 32321117 32321196 0.005674668 −25.63265306Hypo-methylated PCa|NT DMRs chr20 32450338 32450413 0.004037929−35.06122449 Hypo-methylated PCa|NT DMRs chr20 32677589 326778970.000117699 −54.4025974 Hypo-methylated PCa|NT DMRs chr20 3285678032857228 1.79E−12 39.07809524 Hyper-methylated PCa|NT DMRs chr2032978650 32978855 0.003622801 −34.88095238 Hypo-methylated PCa|NT DMRschr20 33146756 33147398 3.36E−05 −25.63809524 Hypo-methylated PCa|NTDMRs chr20 34187634 34189196 0.000260936 30.16071429 Hyper-methylatedPCa|NT DMRs chr20 34190058 34190493 0.000155784 35.72380952Hyper-methylated PCa|NT DMRs chr20 34316555 34329144 0.007383952−27.06603175 Hypo-methylated PCa|NT DMRs chr20 34742966 347430930.001115302 20.62797619 Hyper-methylated PCa|NT DMRs chr20 3508916935089307 0.002097193 −33.83741497 Hypo-methylated PCa|NT DMRs chr2035210565 35233597 0.000308231 29.81166667 Hyper-methylated PCa|NT DMRschr20 36147141 36147987 3.20E−05 −35.3744898 Hypo-methylated PCa|NT DMRschr20 36148716 36150113 9.53E−10 27.6804878 Hyper-methylated PCa|NT DMRschr20 36298866 36299145 0.000457395 −26.23626374 Hypo-methylated PCa|NTDMRs chr20 36526505 36526881 0.009882246 −34.50595238 Hypo-methylatedPCa|NT DMRs chr20 36543025 36552056 8.76E−09 32.9706044 Hyper-methylatedPCa|NT DMRs chr20 37228418 37228532 0.000205174 −47.025 Hypo-methylatedPCa|NT DMRs chr20 37230413 37230564 6.42E−05 45.14285714Hyper-methylated PCa|NT DMRs chr20 37433373 37434397 0.00033768125.30914286 Hyper-methylated PCa|NT DMRs chr20 37435354 374358361.28E−07 40.01133787 Hyper-methylated PCa|NT DMRs chr20 3778479437784928 0.005968871 27.94285714 Hyper-methylated PCa|NT DMRs chr2037897292 38042252 2.27E−05 −25.21028571 Hypo-methylated PCa|NT DMRschr20 38181252 38263740 0.002585277 −29.61428571 Hypo-methylated PCa|NTDMRs chr20 39311309 39312812 2.09E−20 50.318065 Hyper-methylated PCa|NTDMRs chr20 39515963 39516096 0.000205174 27.70892857 Hyper-methylatedPCa|NT DMRs chr20 39526058 39579525 7.79E−05 −22.46481481Hypo-methylated PCa|NT DMRs chr20 41573880 41598857 0.004231599−21.91208791 Hypo-methylated PCa|NT DMRs chr20 41766958 417671910.005513661 −34.375 Hypo-methylated PCa|NT DMRs chr20 41818750 420182834.80E−10 −22.2881459 Hypo-methylated PCa|NT DMRs chr20 42395188 424376220.002193447 −30.504329 Hypo-methylated PCa|NT DMRs chr20 4269709942701838 1.46E−06 39.49343186 Hyper-methylated PCa|NT DMRs chr2042815550 42816152 6.21E−12 25.37272727 Hyper-methylated PCa|NT DMRschr20 42875841 42876602 6.22E−07 32.38662132 Hyper-methylated PCa|NTDMRs chr20 43161153 43161221 0.004007303 −31.83333333 Hypo-methylatedPCa|NT DMRs chr20 43209284 43238439 0.008083098 −20.83333333Hypo-methylated PCa|NT DMRs chr20 43279741 43280062 2.06E−05 39.86360544Hyper-methylated PCa|NT DMRs chr20 43378690 43378973 7.28E−0629.87433862 Hyper-methylated PCa|NT DMRs chr20 43437977 434382556.17E−06 40.42857143 Hyper-methylated PCa|NT DMRs chr20 4396642343973156 0.003032307 −25.1122449 Hypo-methylated PCa|NT DMRs chr2044001656 44001943 1.76E−05 34.25297619 Hyper-methylated PCa|NT DMRschr20 44035317 44037625 1.28E−12 29.33791887 Hyper-methylated PCa|NTDMRs chr20 44518794 44519291 2.33E−10 24.92496392 Hyper-methylatedPCa|NT DMRs chr20 44521160 44521740 0.000118733 42.11111111Hyper-methylated PCa|NT DMRs chr20 44635825 44636206 0.001969641−38.77380952 Hypo-methylated PCa|NT DMRs chr20 44718985 447206570.000585936 −22.0097619 Hypo-methylated PCa|NT DMRs chr20 4472828544728476 5.18E−06 24.37962963 Hyper-methylated PCa|NT DMRs chr2044746651 44747798 0.000377317 28 Hyper-methylated PCa|NT DMRs chr2044751033 44751328 0.005968871 −22.2847619 Hypo-methylated PCa|NT DMRschr20 44791466 44791697 0.001969641 −21.98571429 Hypo-methylated PCa|NTDMRs chr20 44893698 44893857 0.00064571  −44.40816327 Hypo-methylatedPCa|NT DMRs chr20 45017804 45034199 0.00064571  −38.7755102Hypo-methylated PCa|NT DMRs chr20 45269307 45269682 0.000176046−44.17532468 Hypo-methylated PCa|NT DMRs chr20 45312695 453130015.19E−07 −58.54395604 Hypo-methylated PCa|NT DMRs chr20 4583441945834555 0.005968871 −39.45714286 Hypo-methylated PCa|NT DMRs chr2046305188 46305459 0.002097193 −36.96054422 Hypo-methylated PCa|NT DMRschr20 46369875 46391734 2.31E−06 −26.15887446 Hypo-methylated PCa|NTDMRs chr20 46429621 46635704 3.13E−54 −32.98792668 Hypo-methylatedPCa|NT DMRs chr20 46648634 46687893 1.05E−06 −30.76157635Hypo-methylated PCa|NT DMRs chr20 46700377 46839599 8.49E−36−34.12034286 Hypo-methylated PCa|NT DMRs chr20 46925015 470048695.04E−14 −32.67414966 Hypo-methylated PCa|NT DMRs chr20 4702551447105192 5.89E−27 −35.21610942 Hypo-methylated PCa|NT DMRs chr2047128181 47189006 2.99E−18 −36.13184524 Hypo-methylated PCa|NT DMRschr20 47239078 47241358 0.005968871 26.76666667 Hyper-methylated PCa|NTDMRs chr20 47303481 47304240 0.001969641 29.75 Hyper-methylated PCa|NTDMRs chr20 47319660 47323677 0.005249864 24.42857143 Hyper-methylatedPCa|NT DMRs chr20 47439700 47443972 0.000773332 26.1621118Hyper-methylated PCa|NT DMRs chr20 47466744 47466982 0.005513661−23.17857143 Hypo-methylated PCa|NT DMRs chr20 48124365 481531740.001241245 −44.25641026 Hypo-methylated PCa|NT DMRs chr20 4818419548184488 7.87E−05 20.32352941 Hyper-methylated PCa|NT DMRs chr2048533081 48533691 0.005968871 −38.48571429 Hypo-methylated PCa|NT DMRschr20 48657930 48665142 0.007776456 26.94940476 Hyper-methylated PCa|NTDMRs chr20 48889876 48900733 8.77E−05 26.52642089 Hyper-methylatedPCa|NT DMRs chr20 48959845 48965968 0.001969641 43.05714286Hyper-methylated PCa|NT DMRs chr20 49011198 49011586 0.00848240526.76666667 Hyper-methylated PCa|NT DMRs chr20 49011792 490167490.006410012 −28.56147186 Hypo-methylated PCa|NT DMRs chr20 4915788949158302 0.001181579 45.79931973 Hyper-methylated PCa|NT DMRs chr2049208888 49209198 0.000231104 −59.88571429 Hypo-methylated PCa|NT DMRschr20 49212739 49212793 0.004095673 −43.92857143 Hypo-methylated PCa|NTDMRs chr20 49214117 49214325 0.00103773  −28.76269841 Hypo-methylatedPCa|NT DMRs chr20 49307216 49308083 3.61E−10 37.31402116Hyper-methylated PCa|NT DMRs chr20 49483120 49483476 0.00179283 −20.35714286 Hypo-methylated PCa|NT DMRs chr20 49639950 496401200.006410012 20.92857143 Hyper-methylated PCa|NT DMRs chr20 4995841149958821 0.00641359  −23.12301587 Hypo-methylated PCa|NT DMRs chr2050106194 50120864 0.000530246 29.09291005 Hyper-methylated PCa|NT DMRschr20 50187063 50190741 0.005949796 −20.31148459 Hypo-methylated PCa|NTDMRs chr20 50352436 50352690 0.005968871 −49.14952381 Hypo-methylatedPCa|NT DMRs chr20 50369136 50374046 1.97E−05 −49.42285714Hypo-methylated PCa|NT DMRs chr20 51959856 52000535 0.002379616−35.69761905 Hypo-methylated PCa|NT DMRs chr20 52374188 523743140.001969641 −43.34603175 Hypo-methylated PCa|NT DMRs chr20 5420595854261119 0.00023371  −34.86666667 Hypo-methylated PCa|NT DMRs chr2055199769 55203849 1.48E−38 38.81931429 Hyper-methylated PCa|NT DMRschr20 55500054 55500462 1.51E−09 23.76336996 Hyper-methylated PCa|NTDMRs chr20 55842022 55842072 0.005968871 36.10952381 Hyper-methylatedPCa|NT DMRs chr20 55964707 55965826 1.79E−12 45.79126984Hyper-methylated PCa|NT DMRs chr20 55975496 55977927 2.74E−0525.43452381 Hyper-methylated PCa|NT DMRs chr20 55985155 559852780.001969641 40.52380952 Hyper-methylated PCa|NT DMRs chr20 5599341255993730 0.000822388 −26.53246753 Hypo-methylated PCa|NT DMRs chr2056008091 56008227 0.004095673 47.79206349 Hyper-methylated PCa|NT DMRschr20 56014753 56014896 0.005968871 −44.26095238 Hypo-methylated PCa|NTDMRs chr20 56016039 56017850 0.000431954 −21.74801587 Hypo-methylatedPCa|NT DMRs chr20 56025773 56027162 1.12E−06 50.72222222Hyper-methylated PCa|NT DMRs chr20 56035256 56039183 0.00041205321.85833333 Hyper-methylated PCa|NT DMRs chr20 56065548 560709650.009807302 −28.07857143 Hypo-methylated PCa|NT DMRs chr20 5607609256076289 0.00179283  −27.28035714 Hypo-methylated PCa|NT DMRs chr2056124020 56131899 0.000812507 −24.55714286 Hypo-methylated PCa|NT DMRschr20 56168621 56171766 0.006207271 −28.17857143 Hypo-methylated PCa|NTDMRs chr20 56193554 56196229 1.29E−06 37.81428571 Hyper-methylatedPCa|NT DMRs chr20 56227253 56245436 6.86E−20 −36.16281385Hypo-methylated PCa|NT DMRs chr20 56286421 56293119 0.005433534−26.84259259 Hypo-methylated PCa|NT DMRs chr20 56345569 563478830.000836132 −35.75132275 Hypo-methylated PCa|NT DMRs chr20 5651028156523179 0.001637131 −22.84702381 Hypo-methylated PCa|NT DMRs chr2057042168 57045845 4.99E−08 27.85859788 Hyper-methylated PCa|NT DMRschr20 57091832 57098402 0.005968871 −21.48639456 Hypo-methylated PCa|NTDMRs chr20 57143331 57144511 1.42E−05 −20.5647619 Hypo-methylated PCa|NTDMRs chr20 57224696 57225494 3.72E−13 25.94387755 Hyper-methylatedPCa|NT DMRs chr20 57295545 57337922 1.44E−06 −22.60714286Hypo-methylated PCa|NT DMRs chr20 57555770 57555897 0.005968871−39.85714286 Hypo-methylated PCa|NT DMRs chr20 57579515 575819910.00013285  22.79365079 Hyper-methylated PCa|NT DMRs chr20 5758307657583392 0.00064571  36.39795918 Hyper-methylated PCa|NT DMRs chr2057816356 57868338 0.000457395 −33.01391941 Hypo-methylated PCa|NT DMRschr20 58631001 58634023 1.97E−05 49.69142857 Hyper-methylated PCa|NTDMRs chr20 58688881 58691755 0.001471804 24.07380952 Hyper-methylatedPCa|NT DMRs chr20 58797699 58822627 0.006096657 −29.21825397Hypo-methylated PCa|NT DMRs chr20 59053191 59053293 0.00118157927.76190476 Hyper-methylated PCa|NT DMRs chr20 59053543 592153114.15E−14 −31.77423469 Hypo-methylated PCa|NT DMRs chr20 6047052060492722 1.98E−18 −24.54558442 Hypo-methylated PCa|NT DMRs chr2060500037 60500596 0.004236974 −25.66571429 Hypo-methylated PCa|NT DMRschr20 60578837 60578898 0.000117699 −28.31168831 Hypo-methylated PCa|NTDMRs chr20 60596434 60598869 0.002577156 −27.46582633 Hypo-methylatedPCa|NT DMRs chr20 60639173 60639848 1.15E−05 −27.33503401Hypo-methylated PCa|NT DMRs chr20 60677711 60677903 0.00551366131.05059524 Hyper-methylated PCa|NT DMRs chr20 60754003 607541780.001969641 −37.11904762 Hypo-methylated PCa|NT DMRs chr20 6079014460791275 3.03E−08 −33.56451613 Hypo-methylated PCa|NT DMRs chr2060814232 60814900 0.00064571  −27.78646617 Hypo-methylated PCa|NT DMRschr20 60819809 60819888 0.001969641 47.33333333 Hyper-methylated PCa|NTDMRs chr20 60821901 60822245 0.002826041 −39.30272109 Hypo-methylatedPCa|NT DMRs chr20 60881105 60883387 1.10E−07 −26.35064935Hypo-methylated PCa|NT DMRs chr20 60927828 60928238 0.001397404−37.03015873 Hypo-methylated PCa|NT DMRs chr20 60930593 609314370.002193447 −21.51298701 Hypo-methylated PCa|NT DMRs chr20 6093166460932692 5.87E−06 24.94444444 Hyper-methylated PCa|NT DMRs chr2061001789 61003304 5.05E−05 −31.62605042 Hypo-methylated PCa|NT DMRschr20 61022302 61022498 0.003435258 −21.36619048 Hypo-methylated PCa|NTDMRs chr20 61048321 61050272 1.22E−08 20.2956595 Hyper-methylated PCa|NTDMRs chr20 61087268 61088289 2.42E−06 31.43846154 Hyper-methylatedPCa|NT DMRs chr20 61088820 61090463 4.11E−07 −24.78571429Hypo-methylated PCa|NT DMRs chr20 61151391 61152143 7.59E−08−31.51038961 Hypo-methylated PCa|NT DMRs chr20 61158418 611595383.63E−06 21.17403994 Hyper-methylated PCa|NT DMRs chr20 6118536161185456 0.000205174 36.3452381 Hyper-methylated PCa|NT DMRs chr2061187582 61193999 1.13E−05 −26.59501134 Hypo-methylated PCa|NT DMRschr20 61211763 61211873 0.00179283  −20.71071429 Hypo-methylated PCa|NTDMRs chr20 61306941 61309977 0.000412171 20.35340136 Hyper-methylatedPCa|NT DMRs chr20 61325062 61329699 0.000157125 −21.70952381Hypo-methylated PCa|NT DMRs chr20 61337185 61337431 0.00179283 −20.07428571 Hypo-methylated PCa|NT DMRs chr20 61354704 613547570.002585277 −47.23214286 Hypo-methylated PCa|NT DMRs chr20 6135862461360594 6.84E−05 21.73323202 Hyper-methylated PCa|NT DMRs chr2061371408 61372595 1.60E−10 29.69222222 Hyper-methylated PCa|NT DMRschr20 61384301 61384611 0.001241245 −21.37830688 Hypo-methylated PCa|NTDMRs chr20 61391266 61391514 0.001115302 23.375 Hyper-methylated PCa|NTDMRs chr20 61410484 61412536 0.000339757 −42.37489177 Hypo-methylatedPCa|NT DMRs chr20 61416158 61420896 5.87E−08 −28.87404762Hypo-methylated PCa|NT DMRs chr20 61446079 61447276 0.005302622−22.65178571 Hypo-methylated PCa|NT DMRs chr20 61450407 614506840.000354065 32.20634921 Hyper-methylated PCa|NT DMRs chr20 6146451761464689 0.003809353 29.17142857 Hyper-methylated PCa|NT DMRs chr2061507009 61507189 0.003448944 −22.93877551 Hypo-methylated PCa|NT DMRschr20 61554825 61554911 0.005968871 −40.65238095 Hypo-methylated PCa|NTDMRs chr20 61587509 61587829 0.007560755 −31.61607143 Hypo-methylatedPCa|NT DMRs chr20 61605742 61608123 0.00841938  −23.63865546Hypo-methylated PCa|NT DMRs chr20 61609402 61610243 0.00056483529.57095238 Hyper-methylated PCa|NT DMRs chr20 61630617 616308030.001969641 −27.83333333 Hypo-methylated PCa|NT DMRs chr20 6171511561716470 2.84E−08 −28.71493506 Hypo-methylated PCa|NT DMRs chr2061718187 61718767 0.000386426 −27.43452381 Hypo-methylated PCa|NT DMRschr20 61731416 61732480 0.000205174 −24.81845238 Hypo-methylated PCa|NTDMRs chr20 61751153 61756554 5.47E−12 −27.5767316 Hypo-methylated PCa|NTDMRs chr20 61938692 61944033 2.69E−09 −26.3552521 Hypo-methylated PCa|NTDMRs chr20 62042829 62043086 0.000909347 26.25793651 Hyper-methylatedPCa|NT DMRs chr20 62072040 62073213 0.000354065 29.32698413Hyper-methylated PCa|NT DMRs chr20 62077932 62080130 4.13E−06−26.20281385 Hypo-methylated PCa|NT DMRs chr20 62085930 620886554.79E−07 −32.80414747 Hypo-methylated PCa|NT DMRs chr20 6210254862102987 3.60E−08 21.12872024 Hyper-methylated PCa|NT DMRs chr2062116444 62116597 0.00068166  −32.08869048 Hypo-methylated PCa|NT DMRschr20 62131026 62131332 0.000494377 30.12993197 Hyper-methylated PCa|NTDMRs chr20 62164219 62164288 0.007959104 22.36734694 Hyper-methylatedPCa|NT DMRs chr20 62167618 62168604 2.22E−11 −39.24693878Hypo-methylated PCa|NT DMRs chr20 62170689 62170931 0.000972067 −33.5Hypo-methylated PCa|NT DMRs chr20 62173166 62173764 1.60E−10 −26.5906298Hypo-methylated PCa|NT DMRs chr20 62178809 62178860 0.00064571 26.6047619 Hyper-methylated PCa|NT DMRs chr20 62198188 62201158 4.67E−0930.51285714 Hyper-methylated PCa|NT DMRs chr20 62207186 622089230.000205174 −48.72857143 Hypo-methylated PCa|NT DMRs chr20 6222013462222008 2.16E−14 −39.42569444 Hypo-methylated PCa|NT DMRs chr2062244074 62244234 0.001969641 49.40079365 Hyper-methylated PCa|NT DMRschr20 62317724 62319022 5.76E−08 29.07123421 Hyper-methylated PCa|NTDMRs chr20 62328034 62328557 1.55E−08 24.49333333 Hyper-methylatedPCa|NT DMRs chr20 62367007 62370138 1.35E−08 29.8214986 Hyper-methylatedPCa|NT DMRs chr20 62434267 62435863 0.00022692  29.05714286Hyper-methylated PCa|NT DMRs chr20 62461656 62461764 0.00409567332.56746032 Hyper-methylated PCa|NT DMRs chr20 62486691 624893330.000106371 −31.72190476 Hypo-methylated PCa|NT DMRs chr20 6250901962510880 6.22E−07 20.55697279 Hyper-methylated PCa|NT DMRs chr2062522309 62522518 0.005513661 34.20068027 Hyper-methylated PCa|NT DMRschr20 62540851 62544255 0.002585277 −27.96428571 Hypo-methylated PCa|NTDMRs chr20 62570111 62570725 1.42E−11 31.58730159 Hyper-methylatedPCa|NT DMRs chr20 62572875 62573215 1.85E−06 43.49803922Hyper-methylated PCa|NT DMRs chr20 62683031 62684525 8.73E−05−24.02482993 Hypo-methylated PCa|NT DMRs chr20 62685400 626890012.41E−05 30.3686067 Hyper-methylated PCa|NT DMRs chr20 62711559 627121254.10E−05 20.67969925 Hyper-methylated PCa|NT DMRs chr20 6273055462730782 0.001969641 −21.84126984 Hypo-methylated PCa|NT DMRs chr2062738880 62739172 0.001969641 23.61190476 Hyper-methylated PCa|NT DMRschr20 62761065 62765629 0.004236974 −32.00238095 Hypo-methylated PCa|NTDMRs chr20 62795481 62808209 1.11E−05 −22.49201681 Hypo-methylatedPCa|NT DMRs chr20 62826409 62831730 4.97E−06 −26.38543417Hypo-methylated PCa|NT DMRs chr20 62917292 62917489 0.002826041−35.06122449 Hypo-methylated PCa|NT DMRs chr21 19629016 198158592.29E−09 −32.24285714 Hypo-methylated PCa|NT DMRs chr21 1982484020907871 6.58E−22 −34.35731092 Hypo-methylated PCa|NT DMRs chr2121863082 22361964 1.30E−15 −31.69437939 Hypo-methylated PCa|NT DMRschr21 22369363 22370241 4.02E−05 27.66111111 Hyper-methylated PCa|NTDMRs chr21 22987602 23162740 1.21E−07 −26.45739348 Hypo-methylatedPCa|NT DMRs chr21 24349698 24393877 0.00064571  −28.82444444Hypo-methylated PCa|NT DMRs chr21 24412021 25221284 1.50E−31−32.06731951 Hypo-methylated PCa|NT DMRs chr21 25253813 253205352.85E−13 −32.67464286 Hypo-methylated PCa|NT DMRs chr21 2633266626657828 3.72E−11 −28.81083333 Hypo-methylated PCa|NT DMRs chr2126751761 26754835 0.005968871 −21.42380952 Hypo-methylated PCa|NT DMRschr21 27959216 28215691 0.0001882  −26.74920635 Hypo-methylated PCa|NTDMRs chr21 28217974 28219166 1.46E−14 25.17142857 Hyper-methylatedPCa|NT DMRs chr21 28307119 28337820 0.000145094 −27.25873016Hypo-methylated PCa|NT DMRs chr21 28433838 28757505 5.16E−21 −34.6985119Hypo-methylated PCa|NT DMRs chr21 32465775 32486363 0.002400984−23.82349206 Hypo-methylated PCa|NT DMRs chr21 32707165 327073340.00641359  −37.01984127 Hypo-methylated PCa|NT DMRs chr21 3334518933345244 0.001969641 −60.33333333 Hypo-methylated PCa|NT DMRs chr2133393836 33394208 5.19E−07 −52.56776557 Hypo-methylated PCa|NT DMRschr21 33720364 33732136 0.00068166  −35.26666667 Hypo-methylated PCa|NTDMRs chr21 33871659 33871850 0.00064571  −38.80680272 Hypo-methylatedPCa|NT DMRs chr21 34406061 34406715 0.000537598 −25.296 Hypo-methylatedPCa|NT DMRs chr21 34940520 34940655 0.00641359  −36.69444444Hypo-methylated PCa|NT DMRs chr21 34990080 34990123 0.00596887122.5047619 Hyper-methylated PCa|NT DMRs chr21 35467804 355078570.008581782 24.38293651 Hyper-methylated PCa|NT DMRs chr21 3557492335575053 0.000205174 50.67261905 Hyper-methylated PCa|NT DMRs chr2135700156 35718445 3.31E−05 −24.91540616 Hypo-methylated PCa|NT DMRschr21 35738859 35739404 0.005968871 −34.68095238 Hypo-methylated PCa|NTDMRs chr21 35831851 35832142 5.42E−06 20.03760263 Hyper-methylatedPCa|NT DMRs chr21 36877555 36894085 0.00641359  −21.04761905Hypo-methylated PCa|NT DMRs chr21 36900928 36901247 3.50E−05 50.6007326Hyper-methylated PCa|NT DMRs chr21 37081019 37127526 0.005968871−29.00952381 Hypo-methylated PCa|NT DMRs chr21 37485304 374862410.001007739 −21.08829365 Hypo-methylated PCa|NT DMRs chr21 3761868637618829 0.001969641 −57.83673469 Hypo-methylated PCa|NT DMRs chr2137794069 37794558 0.00603903  −37.74867725 Hypo-methylated PCa|NT DMRschr21 37880782 37881862 0.00064571  −34.87037037 Hypo-methylated PCa|NTDMRs chr21 37914560 37915020 1.87E−08 37.98351648 Hyper-methylatedPCa|NT DMRs chr21 38117218 38117455 8.17E−05 −34.38311688Hypo-methylated PCa|NT DMRs chr21 38300427 38301554 0.006096657−44.07142857 Hypo-methylated PCa|NT DMRs chr21 38379654 383812230.000178482 23.30357143 Hyper-methylated PCa|NT DMRs chr21 3859296238598034 7.03E−11 28.8087619 Hyper-methylated PCa|NT DMRs chr21 3891889738919581 1.67E−05 29.30634921 Hyper-methylated PCa|NT DMRs chr2139311492 39334840 0.001969641 −34.89444444 Hypo-methylated PCa|NT DMRschr21 39755553 39755720 0.000972067 −30.44642857 Hypo-methylated PCa|NTDMRs chr21 39813857 39815354 0.000286238 −21.35531136 Hypo-methylatedPCa|NT DMRs chr21 39862516 39880984 0.009807302 32.17904762Hyper-methylated PCa|NT DMRs chr21 40033374 40033635 6.03E−0822.60912698 Hyper-methylated PCa|NT DMRs chr21 40176560 401766940.000974795 30.18452381 Hyper-methylated PCa|NT DMRs chr21 4042110140455576 0.000447319 −39.175 Hypo-methylated PCa|NT DMRs chr21 4116026641160520 0.007494574 −36.18367347 Hypo-methylated PCa|NT DMRs chr2141550841 41550908 0.000117699 −33.52380952 Hypo-methylated PCa|NT DMRschr21 42485213 42485762 0.001969641 42.78231293 Hyper-methylated PCa|NTDMRs chr21 42722029 42729919 0.000286238 −21.55494505 Hypo-methylatedPCa|NT DMRs chr21 42732378 42732745 0.002585277 −22.53214286Hypo-methylated PCa|NT DMRs chr21 42908455 42916105 0.001115302−46.51785714 Hypo-methylated PCa|NT DMRs chr21 43025822 430260590.000117699 −51.81818182 Hypo-methylated PCa|NT DMRs chr21 4310150943102244 1.81E−05 −48.48673469 Hypo-methylated PCa|NT DMRs chr2143182655 43183989 9.63E−06 36.5 Hyper-methylated PCa|NT DMRs chr2143221381 43221433 0.005968871 −33.6 Hypo-methylated PCa|NT DMRs chr2143221581 43222615 1.67E−05 21.27380952 Hyper-methylated PCa|NT DMRschr21 43222808 43222975 0.000205174 −28.67857143 Hypo-methylated PCa|NTDMRs chr21 43481974 43484442 2.05E−05 51.86190476 Hyper-methylatedPCa|NT DMRs chr21 43542566 43546018 0.009781813 25.94047619Hyper-methylated PCa|NT DMRs chr21 43575605 43575871 0.00596887121.17333333 Hyper-methylated PCa|NT DMRs chr21 43685949 436902950.000783791 29.55272109 Hyper-methylated PCa|NT DMRs chr21 4373082543731038 0.001969641 −25.26666667 Hypo-methylated PCa|NT DMRs chr2143784335 43786119 0.007959104 29.7707483 Hyper-methylated PCa|NT DMRschr21 43786285 43786998 8.17E−05 −41.04848485 Hypo-methylated PCa|NTDMRs chr21 43945113 43951322 0.005968871 −22.14935065 Hypo-methylatedPCa|NT DMRs chr21 44013448 44013840 8.96E−05 20.64246032Hyper-methylated PCa|NT DMRs chr21 44072805 44072939 0.005968871−47.12857143 Hypo-methylated PCa|NT DMRs chr21 44074927 440761430.006207271 −23.35714286 Hypo-methylated PCa|NT DMRs chr21 4407990344080174 0.00025637  24.2952381 Hyper-methylated PCa|NT DMRs chr2144165294 44171359 0.007560755 30.59821429 Hyper-methylated PCa|NT DMRschr21 44222891 44227382 0.00641359  20.62539683 Hyper-methylated PCa|NTDMRs chr21 44259715 44260132 0.001181579 25.6 Hyper-methylated PCa|NTDMRs chr21 44373759 44375977 0.000117699 −55.35844156 Hypo-methylatedPCa|NT DMRs chr21 44484698 44484875 0.004947537 −43.26878307Hypo-methylated PCa|NT DMRs chr21 44594030 44594485 0.001419801−23.93571429 Hypo-methylated PCa|NT DMRs chr21 44597135 445973050.001969641 38.33333333 Hyper-methylated PCa|NT DMRs chr21 4460901644609085 0.005968871 −48.74285714 Hypo-methylated PCa|NT DMRs chr2144743146 44743636 0.00064571  −50.84013605 Hypo-methylated PCa|NT DMRschr21 44746073 44746162 0.004057568 51.64285714 Hyper-methylated PCa|NTDMRs chr21 44809968 44810286 0.003448944 38.52721088 Hyper-methylatedPCa|NT DMRs chr21 44818417 44820569 1.05E−18 50.69002976Hyper-methylated PCa|NT DMRs chr21 44847417 44848556 3.37E−1422.23240166 Hyper-methylated PCa|NT DMRs chr21 44876264 448769408.86E−05 29.30238095 Hyper-methylated PCa|NT DMRs chr21 4488353244883776 0.000474737 −42.01587302 Hypo-methylated PCa|NT DMRs chr2145025937 45077944 1.55E−07 28.30587302 Hyper-methylated PCa|NT DMRschr21 45148429 45149333 3.43E−06 35.31318681 Hyper-methylated PCa|NTDMRs chr21 45246278 45247123 0.001241245 −29.54761905 Hypo-methylatedPCa|NT DMRs chr21 45255205 45259032 0.005855202 25.79464286Hyper-methylated PCa|NT DMRs chr21 45280075 45280360 0.001969641−59.13945578 Hypo-methylated PCa|NT DMRs chr21 45336782 453372103.64E−09 56.56302521 Hyper-methylated PCa|NT DMRs chr21 4539317245401133 0.007628253 −39.93877551 Hypo-methylated PCa|NT DMRs chr2145405820 45406212 0.000206041 27.5952381 Hyper-methylated PCa|NT DMRschr21 45507402 45507604 0.005968871 42.94285714 Hyper-methylated PCa|NTDMRs chr21 45566682 45567111 0.00023371  −45.08937729 Hypo-methylatedPCa|NT DMRs chr21 45573632 45574168 0.001969641 42.28968254Hyper-methylated PCa|NT DMRs chr21 45574652 45579761 4.58E−15 45.5125Hyper-methylated PCa|NT DMRs chr21 45585868 45586048 0.001969641−44.38095238 Hypo-methylated PCa|NT DMRs chr21 45604990 456050840.00064571  −36.81632653 Hypo-methylated PCa|NT DMRs chr11 4562249445622932 0.003350175 24.19285714 Hyper-methylated PCa|NT DMRs chr2145626482 45626525 0.005968871 −43.14285714 Hypo-methylated PCa|NT DMRschr21 45626727 45627636 0.000135267 30.40142857 Hyper-methylated PCa|NTDMRs chr21 45662814 45663407 5.61E−06 23.68818342 Hyper-methylatedPCa|NT DMRs chr21 45681828 45684178 0.000303038 −26.4047619Hypo-methylated PCa|NT DMRs chr21 45762023 45769886 4.11E−08−44.96254826 Hypo-methylated PCa|NT DMRs chr21 45770980 457722910.002217636 −23.0235589 Hypo-methylated PCa|NT DMRs chr21 4578670945790853 6.80E−06 −24.26535304 Hypo-methylated PCa|NT DMRs chr2145795149 45795643 8.17E−05 36.22294372 Hyper-methylated PCa|NT DMRschr21 45858462 45859181 4.89E−08 −40.54372294 Hypo-methylated PCa|NTDMRs chr21 45881443 45881685 1.97E−05 −25.09 Hypo-methylated PCa|NT DMRschr21 45918970 45919589 4.96E−06 −29.25421245 Hypo-methylated PCa|NTDMRs chr21 45923111 45924362 4.95E−07 40.74484127 Hyper-methylatedPCa|NT DMRs chr21 45951621 45953661 0.001148141 −21.21611722Hypo-methylated PCa|NT DMRs chr21 46009781 46012423 0.003122338−22.31190476 Hypo-methylated PCa|NT DMRs chr21 46048609 460595370.001899053 −23.45798319 Hypo-methylated PCa|NT DMRs chr21 4605996446066758 0.00064571  −32.43265306 Hypo-methylated PCa|NT DMRs chr2146143226 46143567 9.08E−08 32.65324675 Hyper-methylated PCa|NT DMRschr21 46256658 46257034 0.003229648 −27.52606516 Hypo-methylated PCa|NTDMRs chr21 46331567 46334414 7.95E−05 31.75384615 Hyper-methylatedPCa|NT DMRs chr21 46385125 46388227 1.11E−05 23.76155633Hyper-methylated PCa|NT DMRs chr21 46400608 46400820 5.73E−0526.86335404 Hyper-methylated PCa|NT DMRs chr21 46438025 464383180.000789852 24.82086168 Hyper-methylated PCa|NT DMRs chr21 4667609846677446 9.05E−08 27.9639881 Hyper-methylated PCa|NT DMRs chr21 4673192546737119 0.002097193 −24.02721088 Hypo-methylated PCa|NT DMRs chr2146739385 46739579 0.005968871 37.32857143 Hyper-methylated PCa|NT DMRschr21 46777052 46777646 1.10E−05 −42.48839286 Hypo-methylated PCa|NTDMRs chr21 46851523 46854738 0.000143553 −43.31802721 Hypo-methylatedPCa|NT DMRs chr21 46891483 46892074 5.84E−05 −21.31613757Hypo-methylated PCa|NT DMRs chr21 46932035 46933559 0.001386887−27.22579365 Hypo-methylated PCa|NT DMRs chr21 46955438 469560004.30E−08 41.90289116 Hyper-methylated PCa|NT DMRs chr21 4696285146962991 2.17E−06 22.64511278 Hyper-methylated PCa|NT DMRs chr2147061050 47061209 1.20E−05 −28.24126984 Hypo-methylated PCa|NT DMRschr21 47062234 47062453 2.60E−07 21.23577864 Hyper-methylated PCa|NTDMRs chr21 47307011 47308084 9.60E−06 −37.31714286 Hypo-methylatedPCa|NT DMRs chr21 47394623 47395431 2.13E−08 34.62135642Hyper-methylated PCa|NT DMRs chr21 47401832 47402423 1.72E−0926.33780664 Hyper-methylated PCa|NT DMRs chr21 47546355 475471103.20E−05 −28.6547619 Hypo-methylated PCa|NT DMRs chr21 47716347 477180071.56E−15 35.67684729 Hyper-methylated PCa|NT DMRs chr21 4773699647738292 0.007560755 −36.02467532 Hypo-methylated PCa|NT DMRs chr2147789877 47794099 0.002988739 30.46923077 Hyper-methylated PCa|NT DMRschr21 47799824 47800045 0.005968871 −37.2 Hypo-methylated PCa|NT DMRschr21 47971611 47971863 6.90E−06 56.4 Hyper-methylated PCa|NT DMRs chr2217024712 17041772 0.000840726 −41.84126984 Hypo-methylated PCa|NT DMRschr22 17045516 17070765 1.27E−14 −37.345845 Hypo-methylated PCa|NT DMRschr22 17073132 17079179 1.09E−05 −25.3485119 Hypo-methylated PCa|NT DMRschr22 17092789 17178490 0.007560755 −27.75714286 Hypo-methylated PCa|NTDMRs chr22 17602340 17602562 5.89E−06 37.9789916 Hyper-methylated PCa|NTDMRs chr22 17640812 17640925 0.005968871 −29.27904762 Hypo-methylatedPCa|NT DMRs chr22 18048750 18051695 0.000769918 −29.36813187Hypo-methylated PCa|NT DMRs chr22 18260049 18260960 0.00011226439.43419913 Hyper-methylated PCa|NT DMRs chr22 18267831 182680630.000252289 −28.55102041 Hypo-methylated PCa|NT DMRs chr22 1854579218553990 0.001480644 −32.67142857 Hypo-methylated PCa|NT DMRs chr2218593981 18594193 0.000339627 20.54285714 Hyper-methylated PCa|NT DMRschr22 18894243 18894535 0.000363526 26.00549451 Hyper-methylated PCa|NTDMRs chr22 19091036 19091103 0.000205174 −44.96428571 Hypo-methylatedPCa|NT DMRs chr22 19136326 19136786 3.17E−10 26.63162624Hyper-methylated PCa|NT DMRs chr22 19164879 19165263 0.000339757−32.81755952 Hypo-methylated PCa|NT DMRs chr22 19567516 195675810.00064571  48 Hyper-methylated PCa|NT DMRs chr22 19594773 195951410.004947537 −21.34920635 Hypo-methylated PCa|NT DMRs chr22 1967487819677361 1.66E−10 39.6547619 Hyper-methylated PCa|NT DMRs chr22 1976020619760559 1.76E−06 46.13095238 Hyper-methylated PCa|NT DMRs chr2219861074 19861712 1.55E−08 −42.28038095 Hypo-methylated PCa|NT DMRschr22 19880537 19881265 0.000463506 −26.37662338 Hypo-methylated PCa|NTDMRs chr22 19937121 19941344 0.00657254  −25.89977324 Hypo-methylatedPCa|NT DMRs chr22 19950054 19958632 0.000249429 −26.42730159Hypo-methylated PCa|NT DMRs chr22 19958784 19959377 0.00025142928.23015873 Hyper-methylated PCa|NT DMRs chr22 20019658 200197440.004095673 43.16666667 Hyper-methylated PCa|NT DMRs chr22 2002063620020811 0.00641359  −35.4047619 Hypo-methylated PCa|NT DMRs chr2220103516 20104022 0.000753232 −26.73234127 Hypo-methylated PCa|NT DMRschr22 20145260 20147763 0.001205158 28.13877551 Hyper-methylated PCa|NTDMRs chr22 20217535 20218769 0.00064571  −43.22222222 Hypo-methylatedPCa|NT DMRs chr22 20225578 20225904 0.004266047 23.41341991Hyper-methylated PCa|NT DMRs chr22 20778079 20778698 4.64E−0721.42872024 Hyper-methylated PCa|NT DMRs chr22 20792364 207928204.54E−10 21.10801394 Hyper-methylated PCa|NT DMRs chr22 2138652221387059 7.24E−10 25.69129252 Hyper-methylated PCa|NT DMRs chr2222005751 22006325 5.51E−07 20.14935065 Hyper-methylated PCa|NT DMRschr22 22271664 22271971 0.005968871 −42.24285714 Hypo-methylated PCa|NTDMRs chr22 22471728 22472619 0.003290817 21.86466165 Hyper-methylatedPCa|NT DMRs chr22 22771829 22823769 0.000118596 −20.80357143Hypo-methylated PCa|NT DMRs chr22 22937393 22981516 0.000632596−22.13419913 Hypo-methylated PCa|NT DMRs chr22 23412990 234136665.16E−08 27.75220459 Hyper-methylated PCa|NT DMRs chr22 2346704823483924 0.001789867 −31.33386243 Hypo-methylated PCa|NT DMRs chr2223505542 23505616 0.005968871 −53.6 Hypo-methylated PCa|NT DMRs chr2223793820 23799497 0.001302261 20.31428571 Hyper-methylated PCa|NT DMRschr22 23863086 23863855 0.002245191 −22.08035714 Hypo-methylated PCa|NTDMRs chr22 24192128 24192579 0.003541715 −28.45714286 Hypo-methylatedPCa|NT DMRs chr22 24199008 24199599 3.34E−08 20.23479853Hyper-methylated PCa|NT DMRs chr22 24366534 24366670 0.00596887130.23333333 Hyper-methylated PCa|NT DMRs chr22 24373619 243833250.006466965 −26.21234568 Hypo-methylated PCa|NT DMRs chr22 2482302524823951 0.005438982 30.66904762 Hyper-methylated PCa|NT DMRs chr2224984458 24984864 2.86E−05 −52.68424908 Hypo-methylated PCa|NT DMRschr22 25814354 25817725 3.10E−19 27.87907801 Hyper-methylated PCa|NTDMRs chr22 25960138 25960355 0.00068166  24.425 Hyper-methylated PCa|NTDMRs chr22 26293931 26444050 5.47E−16 −31.08997114 Hypo-methylatedPCa|NT DMRs chr22 26446381 26538668 0.000130438 −27.69904762Hypo-methylated PCa|NT DMRs chr22 26566765 26567014 0.00148064425.17142857 Hyper-methylated PCa|NT DMRs chr22 26574231 266804332.70E−07 −33.03064182 Hypo-methylated PCa|NT DMRs chr22 2668828226821060 9.84E−10 −21.1946712 Hypo-methylated PCa|NT DMRs chr22 2684190926842115 0.00025637  −41.70277778 Hypo-methylated PCa|NT DMRs chr2226848679 26848953 2.80E−05 −57.54945055 Hypo-methylated PCa|NT DMRschr22 27010028 27035502 0.003464153 −22.33939394 Hypo-methylated PCa|NTDMRs chr22 27041156 27048415 0.004095673 −54.62301587 Hypo-methylatedPCa|NT DMRs chr22 27428507 27472362 6.42E−05 −30.59408867Hypo-methylated PCa|NT DMRs chr22 27633325 27640471 0.000642972−21.3702381 Hypo-methylated PCa|NT DMRs chr22 27674906 276955350.000199792 −27.91206349 Hypo-methylated PCa|NT DMRs chr22 2791458227929933 0.005425083 −21.48015873 Hypo-methylated PCa|NT DMRs chr2228005684 28005892 0.007560755 −33.81845238 Hypo-methylated PCa|NT DMRschr22 28063248 28067287 0.000425664 22.76714286 Hyper-methylated PCa|NTDMRs chr22 28198165 28198532 8.77E−12 25.11946779 Hyper-methylatedPCa|NT DMRs chr22 28246057 28277629 0.005968871 −53.33714286Hypo-methylated PCa|NT DMRs chr22 29319928 29340184 0.000297348−46.90327381 Hypo-methylated PCa|NT DMRs chr22 29541931 295423176.42E−05 −44.97883598 Hypo-methylated PCa|NT DMRs chr22 2960435029615295 0.000408406 29.63517665 Hyper-methylated PCa|NT DMRs chr2229698942 29699231 0.005968871 −47.31428571 Hypo-methylated PCa|NT DMRschr22 29709628 29710115 2.40E−09 27.17895545 Hyper-methylated PCa|NTDMRs chr22 29711829 29711970 0.004947537 24.78306878 Hyper-methylatedPCa|NT DMRs chr22 29773939 29774268 0.005968871 −49.60571429Hypo-methylated PCa|NT DMRs chr22 29885209 29886484 0.00551366132.76785714 Hyper-methylated PCa|NT DMRs chr22 30476067 304764337.95E−13 40.14987469 Hyper-methylated PCa|NT DMRs chr22 3064301830644081 0.007239577 24.47301587 Hyper-methylated PCa|NT DMRs chr2230659564 30659983 1.09E−07 31.14897959 Hyper-methylated PCa|NT DMRschr22 30660788 30667250 4.22E−09 44.87155388 Hyper-methylated PCa|NTDMRs chr22 30671142 30679171 1.27E−05 29.24024578 Hyper-methylatedPCa|NT DMRs chr22 30795428 30813744 7.98E−06 −22.57275132Hypo-methylated PCa|NT DMRs chr22 31268306 31268594 0.00064571  −55.6Hypo-methylated PCa|NT DMRs chr22 31432771 31435801 0.006589535−33.68809524 Hypo-methylated PCa|NT DMRs chr22 31480934 314818648.16E−16 23.01428571 Hyper-methylated PCa|NT DMRs chr22 3174418631746971 0.000205174 −22.33333333 Hypo-methylated PCa|NT DMRs chr2232601601 32602722 1.13E−06 −21.96071429 Hypo-methylated PCa|NT DMRschr22 32928683 32930418 0.00025637  −31.90396825 Hypo-methylated PCa|NTDMRs chr22 32948156 32978079 3.20E−06 −26.59389499 Hypo-methylatedPCa|NT DMRs chr22 32983624 32999221 3.44E−06 −26.01041667Hypo-methylated PCa|NT DMRs chr22 33200580 33200931 0.003448944−21.62585034 Hypo-methylated PCa|NT DMRs chr22 33216478 332455481.96E−06 −34.98988095 Hypo-methylated PCa|NT DMRs chr22 3330564533323343 0.00068166  −32.6875 Hypo-methylated PCa|NT DMRs chr22 3335337633353553 0.005968871 −33.72380952 Hypo-methylated PCa|NT DMRs chr2235021919 35090807 0.00010579  −21.97418546 Hypo-methylated PCa|NT DMRschr22 35711812 35712080 5.19E−07 −50.9007326 Hypo-methylated PCa|NT DMRschr22 35748539 35749528 0.006225823 24.31385281 Hyper-methylated PCa|NTDMRs chr22 35827034 35827315 0.001241245 −36.87830688 Hypo-methylatedPCa|NT DMRs chr22 36123779 36123826 0.003622801 −25.45238095Hypo-methylated PCa|NT DMRs chr22 36519405 36519925 0.005023204−37.1672619 Hypo-methylated PCa|NT DMRs chr22 36719573 367242560.003913431 −23.65019841 Hypo-methylated PCa|NT DMRs chr22 3676935536775943 0.00921822  27.18521303 Hyper-methylated PCa|NT DMRs chr2236855559 36855813 0.00064571  −49.3462585 Hypo-methylated PCa|NT DMRschr22 36856901 36860324 0.001969641 27.24047619 Hyper-methylated PCa|NTDMRs chr22 36861148 36861755 2.62E−08 −43.34433498 Hypo-methylatedPCa|NT DMRs chr22 36864139 36864391 0.001969641 51.0452381Hyper-methylated PCa|NT DMRs chr22 36973128 37002514 0.001053932−20.11450216 Hypo-methylated PCa|NT DMRs chr22 37249941 372521520.00064571  −42.75510204 Hypo-methylated PCa|NT DMRs chr22 3746501837465223 1.19E−09 22.63809524 Hyper-methylated PCa|NT DMRs chr2237466349 37471215 7.34E−05 −32.62380952 Hypo-methylated PCa|NT DMRschr22 37482336 37483559 0.001451132 −33.4 Hypo-methylated PCa|NT DMRschr22 37523944 37528414 2.77E−05 −20.58095238 Hypo-methylated PCa|NTDMRs chr22 37637434 37641596 3.46E−06 36.20164835 Hyper-methylatedPCa|NT DMRs chr22 37694128 37697092 0.00179283  45.65892857Hyper-methylated PCa|NT DMRs chr22 37705340 37707327 0.00196964139.90873016 Hyper-methylated PCa|NT DMRs chr22 37720720 377215141.12E−14 30.94480078 Hyper-methylated PCa|NT DMRs chr22 3774210837742350 6.42E−05 −44.3968254 Hypo-methylated PCa|NT DMRs chr22 3779635837798484 0.000117699 −41.04761905 Hypo-methylated PCa|NT DMRs chr2237880096 37882206 5.60E−19 53.38805488 Hyper-methylated PCa|NT DMRschr22 37897473 37898146 0.002034353 −35.47959184 Hypo-methylated PCa|NTDMRs chr22 37908752 37909243 0.003290817 −55.38392857 Hypo-methylatedPCa|NT DMRs chr22 37922526 37937792 0.00248539  −21.93095238Hypo-methylated PCa|NT DMRs chr22 37942798 37943189 0.001391421−23.31428571 Hypo-methylated PCa|NT DMRs chr22 37961882 379626462.24E−06 38.91707718 Hyper-methylated PCa|NT DMRs chr22 3803610138037250 0.004496757 22.58646617 Hyper-methylated PCa|NT DMRs chr2238104589 38104800 6.42E−05 37.70740741 Hyper-methylated PCa|NT DMRschr22 38130443 38131296 0.005513661 −34.30136054 Hypo-methylated PCa|NTDMRs chr22 38221127 38221213 0.00023371  22.08571429 Hyper-methylatedPCa|NT DMRs chr22 38434955 38435760 4.11E−06 −26.39417989Hypo-methylated PCa|NT DMRs chr22 38465060 38466279 0.001076343−28.59090909 Hypo-methylated PCa|NT DMRs chr22 38610287 386109540.000916248 21.78042328 Hyper-methylated PCa|NT DMRs chr22 3868738138687683 0.001789867 −25.87142857 Hypo-methylated PCa|NT DMRs chr2238695196 38696915 1.00E−09 −26.60842491 Hypo-methylated PCa|NT DMRschr22 38809164 38809414 5.84E−05 −43.76984127 Hypo-methylated PCa|NTDMRs chr22 38848522 38850791 0.001775064 29.30793651 Hyper-methylatedPCa|NT DMRs chr22 39173212 39173562 3.58E−07 −21.75124717Hypo-methylated PCa|NT DMRs chr22 39257118 39261056 0.002218812−20.09047619 Hypo-methylated PCa|NT DMRs chr22 39395611 394015130.000205174 −20.39404762 Hypo-methylated PCa|NT DMRs chr22 3941676439417804 0.00179283  37.69345238 Hyper-methylated PCa|NT DMRs chr2239540123 39540675 2.03E−05 27.49583333 Hyper-methylated PCa|NT DMRschr22 39572270 39572680 0.00046742  −57.4004329 Hypo-methylated PCa|NTDMRs chr22 39584970 39599577 0.001969641 −22.82571429 Hypo-methylatedPCa|NT DMRs chr22 39650960 39651432 0.001224841 31.45238095Hyper-methylated PCa|NT DMRs chr22 39686867 39687020 0.00064571 −29.91005291 Hypo-methylated PCa|NT DMRs chr22 39688750 396900400.00068166  −26.48412698 Hypo-methylated PCa|NT DMRs chr22 3969364939696527 0.000452947 27.33730159 Hyper-methylated PCa|NT DMRs chr2239712694 39714432 1.02E−05 −28.39214286 Hypo-methylated PCa|NT DMRschr22 39852622 39852965 0.000371379 −26.3022409 Hypo-methylated PCa|NTDMRs chr22 39919480 39925038 7.74E−06 −38.19805195 Hypo-methylatedPCa|NT DMRs chr22 39977457 39984289 0.000205174 −23.47321429Hypo-methylated PCa|NT DMRs chr22 40059727 40060150 4.84E−06−32.50526316 Hypo-methylated PCa|NT DMRs chr22 40081350 400830934.33E−11 25.52153846 Hyper-methylated PCa|NT DMRs chr22 4077455440800716 4.37E−05 29.37993197 Hyper-methylated PCa|NT DMRs chr2240800876 40800984 0.001969641 −22.81746032 Hypo-methylated PCa|NT DMRschr22 41047920 41048830 2.45E−07 −30.92019704 Hypo-methylated PCa|NTDMRs chr22 41776426 41777140 1.44E−05 −38.8531746 Hypo-methylated PCa|NTDMRs chr22 41808582 41809115 0.002105149 27.13047619 Hyper-methylatedPCa|NT DMRs chr22 42063193 42071305 0.000354065 −32.02486772Hypo-methylated PCa|NT DMRs chr22 42195954 42196351 0.00014204126.22435897 Hyper-methylated PCa|NT DMRs chr22 42305466 423063556.15E−09 24.93557423 Hyper-methylated PCa|NT DMRs chr22 4272102042724987 0.000457395 39.86556777 Hyper-methylated PCa|NT DMRs chr2242832817 42833445 0.00967147  −25.51428571 Hypo-methylated PCa|NT DMRschr22 42896908 42912274 0.006220956 −21.90714286 Hypo-methylated PCa|NTDMRs chr22 43089582 43089699 0.002437742 41.60846561 Hyper-methylatedPCa|NT DMRs chr22 43165992 43167431 1.55E−05 −38.05300207Hypo-methylated PCa|NT DMRs chr22 43264804 43264940 0.005968871 −39.24Hypo-methylated PCa|NT DMRs chr22 43524163 43524623 0.00103937829.72161172 Hyper-methylated PCa|NT DMRs chr22 43543732 435458040.001577531 38.71941392 Hyper-methylated PCa|NT DMRs chr22 4357016843572461 0.001004629 −21.95069124 Hypo-methylated PCa|NT DMRs chr2243582083 43582320 1.97E−05 −36.96285714 Hypo-methylated PCa|NT DMRschr22 43593647 43595250 0.002217888 −28.08974359 Hypo-methylated PCa|NTDMRs chr22 43652842 43653384 0.000836132 42.08201058 Hyper-methylatedPCa|NT DMRs chr22 43659512 43660959 7.91E−07 39.90123457Hyper-methylated PCa|NT DMRs chr22 43673779 43674170 0.00064571 −31.6447619 Hypo-methylated PCa|NT DMRs chr22 43688189 436894980.000205174 −48.96428571 Hypo-methylated PCa|NT DMRs chr22 4369348943694062 6.42E−05 −57.01058201 Hypo-methylated PCa|NT DMRs chr2243807305 43807614 8.06E−09 27.84505495 Hyper-methylated PCa|NT DMRschr22 43820980 43822229 0.00049771  −25.09166667 Hypo-methylated PCa|NTDMRs chr22 44130551 44130859 0.005968871 −60.86666667 Hypo-methylatedPCa|NT DMRs chr22 44220726 44227169 0.00013778  −36.04139194Hypo-methylated PCa|NT DMRs chr22 44391797 44391940 1.97E−05 46.4452381Hyper-methylated PCa|NT DMRs chr22 44421022 44421293 0.00068166 20.35059524 Hyper-methylated PCa|NT DMRs chr22 44422163 444356090.001881239 23.6154195 Hyper-methylated PCa|NT DMRs chr22 4444275444464996 0.002847038 25.51198686 Hyper-methylated PCa|NT DMRs chr2244494384 44495099 0.002225326 22.08163265 Hyper-methylated PCa|NT DMRschr22 44598763 44598834 0.001969641 −40.42857143 Hypo-methylated PCa|NTDMRs chr22 44697106 44708468 1.48E−05 −21.92795031 Hypo-methylatedPCa|NT DMRs chr22 44796176 44796400 0.00603903  −21.73544974Hypo-methylated PCa|NT DMRs chr22 44807644 44807931 0.000181485−20.49417989 Hypo-methylated PCa|NT DMRs chr22 44894632 449288410.001969641 −32.57936508 Hypo-methylated PCa|NT DMRs chr22 4497375444973767 0.005968871 28.16 Hyper-methylated PCa|NT DMRs chr22 4505510445055322 0.00064571  −29.31020408 Hypo-methylated PCa|NT DMRs chr2245124762 45126133 1.00E−10 36.41058201 Hyper-methylated PCa|NT DMRschr22 45149396 45154567 0.000554791 −32.76106443 Hypo-methylated PCa|NTDMRs chr22 45235453 45236728 9.29E−05 30.76857143 Hyper-methylatedPCa|NT DMRs chr22 45277187 45277773 6.49E−05 −20.12566138Hypo-methylated PCa|NT DMRs chr22 45368388 45368994 0.007560755−21.74464286 Hypo-methylated PCa|NT DMRs chr22 45621915 456328401.54E−06 25.83042973 Hyper-methylated PCa|NT DMRs chr22 4583672245836814 0.00641359  25.14285714 Hyper-methylated PCa|NT DMRs chr2245898180 45898468 2.24E−06 24.28809524 Hyper-methylated PCa|NT DMRschr22 45914606 45915974 0.001041871 −26.01203008 Hypo-methylated PCa|NTDMRs chr22 45976965 45977103 0.001969641 29.64285714 Hyper-methylatedPCa|NT DMRs chr22 46028669 46029145 7.95E−05 29.01025641Hyper-methylated PCa|NT DMRs chr22 46202942 46230312 0.008482405 −51.52Hypo-methylated PCa|NT DMRs chr22 46263747 46266563 0.00109025126.1552381 Hyper-methylated PCa|NT DMRs chr22 46292209 462926650.001969641 −46.06746032 Hypo-methylated PCa|NT DMRs chr22 4633063146330781 0.001969641 −38.36111111 Hypo-methylated PCa|NT DMRs chr2246392030 46392731 5.21E−09 34.48130511 Hyper-methylated PCa|NT DMRschr22 46450034 46454866 0.004216674 −22.77242525 Hypo-methylated PCa|NTDMRs chr22 46457715 46466113 1.64E−07 −24.14420929 Hypo-methylatedPCa|NT DMRs chr22 46683803 46684365 0.000122686 40.04251701Hyper-methylated PCa|NT DMRs chr22 46770769 46771303 5.40E−06−39.10873016 Hypo-methylated PCa|NT DMRs chr22 46786662 467871150.00023371  −51.61190476 Hypo-methylated PCa|NT DMRs chr22 4692160646921968 1.42E−05 −50.39795918 Hypo-methylated PCa|NT DMRs chr2246934021 46934839 1.10E−15 38.06646403 Hyper-methylated PCa|NT DMRschr22 46973538 46975007 0.000374633 28.12916667 Hyper-methylated PCa|NTDMRs chr22 46982366 46983354 0.000199043 24.5026455 Hyper-methylatedPCa|NT DMRs chr22 47018235 47022351 0.001221691 29.37585034Hyper-methylated PCa|NT DMRs chr22 47036663 47037018 9.61E−05−23.27731092 Hypo-methylated PCa|NT DMRs chr22 47057846 470585795.90E−07 −34.44071429 Hypo-methylated PCa|NT DMRs chr22 4706886947071292 3.74E−06 33.84873354 Hyper-methylated PCa|NT DMRs chr2247143597 47143983 0.005968871 −46.41714286 Hypo-methylated PCa|NT DMRschr22 47170473 47170814 1.42E−05 44.95306122 Hyper-methylated PCa|NTDMRs chr22 47242609 47242924 9.61E−05 24.16890756 Hyper-methylatedPCa|NT DMRs chr22 47465566 47465709 5.94E−06 −60.44545455Hypo-methylated PCa|NT DMRs chr22 47550304 47550383 0.004095673−52.78571429 Hypo-methylated PCa|NT DMRs chr22 47590058 475951905.02E−05 −26.57142857 Hypo-methylated PCa|NT DMRs chr22 4764337447646813 6.22E−05 −27.61258503 Hypo-methylated PCa|NT DMRs chr2247672954 47678313 1.21E−06 −27.70634921 Hypo-methylated PCa|NT DMRschr22 47770840 47784735 3.98E−06 −22.65 Hypo-methylated PCa|NT DMRschr22 47786550 47788537 2.80E−05 −24.11428571 Hypo-methylated PCa|NTDMRs chr22 47797235 47797962 0.00068166  −29.8 Hypo-methylated PCa|NTDMRs chr22 47945842 47960854 0.000150872 −23.26995074 Hypo-methylatedPCa|NT DMRs chr22 47970957 48005598 7.49E−08 −32.65176651Hypo-methylated PCa|NT DMRs chr22 48017883 48035016 2.47E−10−30.74817276 Hypo-methylated PCa|NT DMRs chr22 48071275 481433984.61E−19 −24.40392157 Hypo-methylated PCa|NT DMRs chr22 4817419248178836 3.66E−05 −27.67619048 Hypo-methylated PCa|NT DMRs chr2248206445 48258257 1.04E−08 −26.15607143 Hypo-methylated PCa|NT DMRschr22 48281451 48445323 5.89E−25 −29.92323391 Hypo-methylated PCa|NTDMRs chr22 48542623 48569409 5.01E−06 −34.77738095 Hypo-methylatedPCa|NT DMRs chr22 48594441 48594664 0.005968871 25.08571429Hyper-methylated PCa|NT DMRs chr22 48605245 48633392 2.65E−07−22.86575481 Hypo-methylated PCa|NT DMRs chr22 48705680 487101480.003464153 −23.09090909 Hypo-methylated PCa|NT DMRs chr22 4872219348730913 3.32E−14 −27.12244898 Hypo-methylated PCa|NT DMRs chr2248788912 48790788 4.33E−05 −29.44688645 Hypo-methylated PCa|NT DMRschr22 48827012 48852751 3.60E−16 −29.7236715 Hypo-methylated PCa|NT DMRschr22 48907552 48928174 1.94E−31 −26.12090942 Hypo-methylated PCa|NTDMRs chr22 48932080 48933016 2.13E−12 −50.99246032 Hypo-methylatedPCa|NT DMRs chr22 48934921 48935788 0.001969641 −40.86031746Hypo-methylated PCa|NT DMRs chr22 48973192 48973360 0.000463506−26.19264069 Hypo-methylated PCa|NT DMRs chr22 48974998 489762852.14E−05 −30.21929825 Hypo-methylated PCa|NT DMRs chr22 4898838048993091 1.76E−13 −26.89069264 Hypo-methylated PCa|NT DMRs chr2248998843 48999382 1.24E−07 −26.60952381 Hypo-methylated PCa|NT DMRschr22 49002925 49005619 1.57E−06 −29.97321429 Hypo-methylated PCa|NTDMRs chr22 49012868 49020659 1.03E−05 −36.19917898 Hypo-methylatedPCa|NT DMRs chr22 49057203 49079052 7.67E−25 −24.79627329Hypo-methylated PCa|NT DMRs chr22 49098544 49098733 0.00494753733.15608466 Hyper-methylated PCa|NT DMRs chr22 49114811 491159231.21E−06 −27.14679089 Hypo-methylated PCa|NT DMRs chr22 4920012949203804 6.66E−09 −23.6365353 Hypo-methylated PCa|NT DMRs chr22 4936889549369808 1.76E−06 −29.58809524 Hypo-methylated PCa|NT DMRs chr2249413871 49442520 2.65E−28 −28.24208683 Hypo-methylated PCa|NT DMRschr22 49447831 49456655 1.57E−05 −26.15494505 Hypo-methylated PCa|NTDMRs chr22 49477254 49485253 4.65E−09 −31.91717172 Hypo-methylatedPCa|NT DMRs chr22 49485941 49489584 2.08E−07 −32.37234432Hypo-methylated PCa|NT DMRs chr22 49490948 49549413 2.37E−31−27.66451701 Hypo-methylated PCa|NT DMRs chr22 49993535 499946261.67E−08 −25.87728938 Hypo-methylated PCa|NT DMRs chr22 4999470249994865 0.005968871 24.67619048 Hyper-methylated PCa|NT DMRs chr2250042460 50047785 2.44E−07 −33.31547619 Hypo-methylated PCa|NT DMRschr22 50050819 50052205 1.42E−05 28.34183673 Hyper-methylated PCa|NTDMRs chr22 50052375 50060289 4.80E−11 −32.49013605 Hypo-methylatedPCa|NT DMRs chr22 50098234 50098524 7.78E−07 27.59849624Hyper-methylated PCa|NT DMRs chr22 50107193 50115324 1.19E−09−24.95110337 Hypo-methylated PCa|NT DMRs chr22 50120593 501221050.0003047  28.28095238 Hyper-methylated PCa|NT DMRs chr22 5016265050162854 0.003577362 −44.03968254 Hypo-methylated PCa|NT DMRs chr2250164112 50165439 4.38E−07 20.38888889 Hyper-methylated PCa|NT DMRschr22 50201727 50208045 0.001732398 27.22559524 Hyper-methylated PCa|NTDMRs chr22 50231946 50232926 1.47E−06 37.90814132 Hyper-methylatedPCa|NT DMRs chr22 50241737 50241917 1.87E−06 30.88359788Hyper-methylated PCa|NT DMRs chr22 50243185 50245708 1.98E−0523.50443723 Hyper-methylated PCa|NT DMRs chr22 50319194 503197476.94E−06 56.84603175 Hyper-methylated PCa|NT DMRs chr22 5032839150328954 1.01E−05 30.859447 Hyper-methylated PCa|NT DMRs chr22 5034152750344608 1.12E−10 −38.61342857 Hypo-methylated PCa|NT DMRs chr2250347721 50348626 0.008581782 −23.14761905 Hypo-methylated PCa|NT DMRschr22 50356209 50358974 0.000598356 −27.1039897 Hypo-methylated PCa|NTDMRs chr22 50359001 50361044 0.000409331 28.82352941 Hyper-methylatedPCa|NT DMRs chr22 50435311 50435944 0.000392715 −41.15714286Hypo-methylated PCa|NT DMRs chr22 50444827 50447047 1.97E−05−48.86190476 Hypo-methylated PCa|NT DMRs chr22 50450635 504530704.36E−05 −24.02522046 Hypo-methylated PCa|NT DMRs chr22 5046588750466283 0.00068166  −38.57738095 Hypo-methylated PCa|NT DMRs chr2250472321 50483852 4.42E−08 32.18455026 Hyper-methylated PCa|NT DMRschr22 50492324 50492421 0.001969641 −26.6984127 Hypo-methylated PCa|NTDMRs chr22 50494218 50497649 4.47E−10 21.6475469 Hyper-methylated PCa|NTDMRs chr22 50499344 50501125 7.21E−06 31.93537415 Hyper-methylatedPCa|NT DMRs chr22 50507018 50507076 0.00068166  −27.96428571Hypo-methylated PCa|NT DMRs chr22 50522294 50528562 3.55E−06 22.92857143Hyper-methylated PCa|NT DMRs chr22 50550439 50551233 0.00551366136.83035714 Hyper-methylated PCa|NT DMRs chr22 50586613 505881850.004649531 22.81772487 Hyper-methylated PCa|NT DMRs chr22 5060773050608034 6.54E−05 27.2464986 Hyper-methylated PCa|NT DMRs chr22 5064051450640915 0.007679542 −23.97959184 Hypo-methylated PCa|NT DMRs chr2250689963 50690499 1.15E−05 25.39809524 Hyper-methylated PCa|NT DMRschr22 50720245 50722032 4.98E−11 −38.76097561 Hypo-methylated PCa|NTDMRs chr22 50879384 50879642 0.002291701 −24.25595238 Hypo-methylatedPCa|NT DMRs chr22 50920427 50925202 1.88E−05 −25.15691057Hypo-methylated PCa|NT DMRs chr22 50965219 50965614 0.00039615941.15428571 Hyper-methylated PCa|NT DMRs chr22 50975834 509811990.007679542 39.06349206 Hyper-methylated PCa|NT DMRs chr22 5100205051010074 0.002902476 −28.38612836 Hypo-methylated PCa|NT DMRs chr2251039741 51044178 1.47E−18 28.0995873 Hyper-methylated PCa|NT DMRs chr2251110120 51112461 2.82E−07 36.80444444 Hyper-methylated PCa|NT DMRschr22 51135020 51136679 1.43E−17 −49.90679012 Hypo-methylated PCa|NTDMRs chr22 51142482 51143093 9.98E−06 20.38408163 Hyper-methylatedPCa|NT DMRs chrX 3419738 3467842 1.33E−05 −34.39375 Hypo-methylatedPCa|NT DMRs chrX 3622147 3630620 0.008255277 23.07956349Hyper-methylated PCa|NT DMRs chrX 3674948 3719664 0.001129594−30.88928571 Hypo-methylated PCa|NT DMRs chrX 3857943 4198134 5.09E−11−37.01630592 Hypo-methylated PCa|NT DMRs chrX 6196153 6532728 7.74E−13−30.06666667 Hypo-methylated PCa|NT DMRs chrX 9307696 93092310.001451132 44.29365079 Hyper-methylated PCa|NT DMRs chrX 98485799848638 0.001969641 −46.07142857 Hypo-methylated PCa|NT DMRs chrX10126409 10139038 0.001243418 23.7547619 Hyper-methylated PCa|NT DMRschrX 10141439 10141658 0.003314163 −20.95952381 Hypo-methylated PCa|NTDMRs chrX 11577770 11639205 0.007560755 −27.27857143 Hypo-methylatedPCa|NT DMRs chrX 11682516 11682732 0.000260826 23.39583333Hyper-methylated PCa|NT DMRs chrX 12982947 12992733 0.00391995629.58795518 Hyper-methylated PCa|NT DMRs chrX 15518992 156064350.000564835 35.35714286 Hyper-methylated PCa|NT DMRs chrX 1890544918905522 0.00068166  28.07440476 Hyper-methylated PCa|NT DMRs chrX19765856 19776416 0.007776456 38.18639456 Hyper-methylated PCa|NT DMRschrX 20285567 20287640 6.92E−09 34.56615187 Hyper-methylated PCa|NT DMRschrX 21674268 21677027 9.11E−20 33.54954128 Hyper-methylated PCa|NT DMRschrX 21961090 21971275 0.00064571  −46.96802721 Hypo-methylated PCa|NTDMRs chrX 23353489 23353964 0.006407159 27.23073593 Hyper-methylatedPCa|NT DMRs chrX 23804818 23815719 0.005968871 −52.88 Hypo-methylatedPCa|NT DMRs chrX 24412948 24413615 0.005968871 −33.10095238Hypo-methylated PCa|NT DMRs chrX 24665662 24665883 0.00848240529.15238095 Hyper-methylated PCa|NT DMRs chrX 27398486 27399915 6.42E−05−43.56031746 Hypo-methylated PCa|NT DMRs chrX 27481149 275367120.000205174 −36.3827381 Hypo-methylated PCa|NT DMRs chrX 3063138130631486 0.002437742 30.91481481 Hyper-methylated PCa|NT DMRs chrX38080365 38080757 0.000334554 29.94395604 Hyper-methylated PCa|NT DMRschrX 38422277 38558038 0.006225823 −21.81298701 Hypo-methylated PCa|NTDMRs chrX 38950001 39017430 0.002097193 −30.42517007 Hypo-methylatedPCa|NT DMRs chrX 39021905 39021937 0.005968871 32.1952381Hyper-methylated PCa|NT DMRs chrX 39297702 39435492 2.47E−06−21.87305459 Hypo-methylated PCa|NT DMRs chrX 39615035 396155370.000117699 −53.91125541 Hypo-methylated PCa|NT DMRs chrX 3963172439639881 0.007959104 35.85646259 Hyper-methylated PCa|NT DMRs chrX39673244 39676247 6.42E−05 −54.96825397 Hypo-methylated PCa|NT DMRs chrX39764542 39765088 1.81E−05 −22.59489796 Hypo-methylated PCa|NT DMRs chrX39871593 39872580 2.89E−13 23.30279503 Hyper-methylated PCa|NT DMRs chrX40003285 40005082 4.38E−05 29.24196429 Hyper-methylated PCa|NT DMRs chrX40064796 40064977 0.000339757 24.82900433 Hyper-methylated PCa|NT DMRschrX 40275150 40309312 0.00641359  −30.09365079 Hypo-methylated PCa|NTDMRs chrX 40401751 40401820 0.003448944 −21.40816327 Hypo-methylatedPCa|NT DMRs chrX 40703267 40718169 0.005513661 −23.25238095Hypo-methylated PCa|NT DMRs chrX 41098538 41099478 0.00387103530.73511905 Hyper-methylated PCa|NT DMRs chrX 41343060 413432560.003622801 25.54761905 Hyper-methylated PCa|NT DMRs chrX 4374164443774238 7.86E−08 26.39295238 Hyper-methylated PCa|NT DMRs chrX 4420359644203713 6.42E−05 45.17248677 Hyper-methylated PCa|NT DMRs chrX 4476000444769593 0.00023371  −22.97380952 Hypo-methylated PCa|NT DMRs chrX45060311 45060916 0.008482405 49.11619048 Hyper-methylated PCa|NT DMRschrX 46433978 46434846 2.76E−32 24.56271429 Hyper-methylated PCa|NT DMRschrX 47199127 47204759 0.003448944 −23.91564626 Hypo-methylated PCa|NTDMRs chrX 47444646 47446158 1.04E−05 −22.27819549 Hypo-methylated PCa|NTDMRs chrX 48324152 48325878 0.001111028 −26.19100529 Hypo-methylatedPCa|NT DMRs chrX 48409193 48409405 0.005968871 26.99047619Hyper-methylated PCa|NT DMRs chrX 48769661 48769849 0.001129594−28.40674603 Hypo-methylated PCa|NT DMRs chrX 49013813 490145170.001241245 −40.72486772 Hypo-methylated PCa|NT DMRs chrX 4902131049023724 1.45E−17 47.8535892 Hyper-methylated PCa|NT DMRs chrX 4910510749105166 0.001969641 −43.67063492 Hypo-methylated PCa|NT DMRs chrX51138687 51139482 3.72E−07 32.66917293 Hyper-methylated PCa|NT DMRs chrX51380484 51437482 0.001969641 −35.72108844 Hypo-methylated PCa|NT DMRschrX 51718426 51778515 5.84E−05 −41.18690476 Hypo-methylated PCa|NT DMRschrX 53460616 53460813 0.003622801 −39.95634921 Hypo-methylated PCa|NTDMRs chrX 53468979 53469023 0.001969641 37.28571429 Hyper-methylatedPCa|NT DMRs chrX 53720736 53720938 0.001969641 −35.8531746Hypo-methylated PCa|NT DMRs chrX 54068973 54069131 0.005968871−31.41428571 Hypo-methylated PCa|NT DMRs chrX 54385317 54385690 6.42E−0542.96825397 Hyper-methylated PCa|NT DMRs chrX 56790661 567907960.000149331 −41.2961039 Hypo-methylated PCa|NT DMRs chrX 6363896463929683 0.000117699 −45.90909091 Hypo-methylated PCa|NT DMRs chrX64851067 64879510 0.000481535 −23.07142857 Hypo-methylated PCa|NT DMRschrX 64887811 64888466 0.000225685 26.51666667 Hyper-methylated PCa|NTDMRs chrX 67802415 67822868 0.001850915 −28.74107143 Hypo-methylatedPCa|NT DMRs chrX 68050207 68050396 0.000840726 29.21534392Hyper-methylated PCa|NT DMRs chrX 68344900 68348695 0.00103773835.24571429 Hyper-methylated PCa|NT DMRs chrX 68353870 683540670.005968871 −24.66190476 Hypo-methylated PCa|NT DMRs chrX 7015069270151166 1.04E−07 24.64980159 Hyper-methylated PCa|NT DMRs chrX 7088263570882792 0.00064571  58.09183673 Hyper-methylated PCa|NT DMRs chrX71308129 71318356 0.000974795 40.57440476 Hyper-methylated PCa|NT DMRschrX 71524800 71525167 1.27E−05 41.64761905 Hyper-methylated PCa|NT DMRschrX 76286504 76599326 6.69E−05 −38.93666667 Hypo-methylated PCa|NT DMRschrX 76703773 76704067 1.97E−05 47.39761905 Hyper-methylated PCa|NT DMRschrX 84111607 84150561 0.000205174 −38.50952381 Hypo-methylated PCa|NTDMRs chrX 84581332 84940950 9.01E−09 −35.6447619 Hypo-methylated PCa|NTDMRs chrX 85415435 85975267 4.90E−08 −37.0004329 Hypo-methylated PCa|NTDMRs chrX 97635798 98196647 4.11E−14 −26.20857143 Hypo-methylated PCa|NTDMRs chrX 98627197 98627273 0.00064571  −32.14081633 Hypo-methylatedPCa|NT DMRs chrX 98802699 99049297 2.59E−08 −26.62557319 Hypo-methylatedPCa|NT DMRs chrX 99306261 99551652 7.78E−07 −32.74636591 Hypo-methylatedPCa|NT DMRs chrX 99662504 99663256 0.000149336 34.26078431Hyper-methylated PCa|NT DMRs chrX 99663460 99663576 1.42E−05 22.98809524Hyper-methylated PCa|NT DMRs chrX 100545995 100546334 4.63E−1021.31514042 Hyper-methylated PCa|NT DMRs chrX 100805372 1008057900.00185014  33.01768707 Hyper-methylated PCa|NT DMRs chrX 101429500101440472 0.000396159 −33.19190476 Hypo-methylated PCa|NT DMRs chrX101802112 101802437 0.00179283  29.81845238 Hyper-methylated PCa|NT DMRschrX 102001147 102001558 6.58E−10 30.90646259 Hyper-methylated PCa|NTDMRs chrX 103295075 103331097 2.86E−07 −40.23537415 Hypo-methylatedPCa|NT DMRs chrX 103977994 103978159 0.008482405 −37.78761905Hypo-methylated PCa|NT DMRs chrX 105066606 105066895 0.00196964130.52380952 Hyper-methylated PCa|NT DMRs chrX 106694438 1066948440.000205174 45.4375 Hyper-methylated PCa|NT DMRs chrX 106961830106982201 0.002593284 −29.16292517 Hypo-methylated PCa|NT DMRs chrX107887851 107978125 0.003205074 24.8012987 Hyper-methylated PCa|NT DMRschrX 108868182 108868383 4.96E−06 27.69413919 Hyper-methylated PCa|NTDMRs chrX 109058243 109158681 1.82E−06 −21.90915751 Hypo-methylatedPCa|NT DMRs chrX 109416507 109416654 0.005968871 −55.81428571Hypo-methylated PCa|NT DMRs chrX 113817280 113817410 0.00020517422.67857143 Hyper-methylated PCa|NT DMRs chrX 114956670 1149575310.001969641 42.76507937 Hyper-methylated PCa|NT DMRs chrX 117250111117250305 2.25E−05 21.02055138 Hyper-methylated PCa|NT DMRs chrX118407331 118418067 0.000191452 30.31904762 Hyper-methylated PCa|NT DMRschrX 118491924 118496048 0.00023371  −23.12333333 Hypo-methylated PCa|NTDMRs chrX 118653545 118666617 0.00576331  21.94047619 Hyper-methylatedPCa|NT DMRs chrX 118751692 118753211 0.00064571  46.3537415Hyper-methylated PCa|NT DMRs chrX 118893071 118894740 0.00020562  20.44Hyper-methylated PCa|NT DMRs chrX 119124902 119147515 1.22E−0627.84315476 Hyper-methylated PCa|NT DMRs chrX 119404939 1194582573.93E−05 23.22559524 Hyper-methylated PCa|NT DMRs chrX 122317388122318642 1.32E−08 33.21964286 Hyper-methylated PCa|NT DMRs chrX123480537 123480938 2.06E−05 22.09557823 Hyper-methylated PCa|NT DMRschrX 125430259 125679623 1.24E−07 −33.70038095 Hypo-methylated PCa|NTDMRs chrX 125685949 125686094 0.001115302 −30.43928571 Hypo-methylatedPCa|NT DMRs chrX 125807571 125864841 2.44E−07 −28.01292517Hypo-methylated PCa|NT DMRs chrX 126120088 127066119 1.14E−11−27.85537415 Hypo-methylated PCa|NT DMRs chrX 128901556 1289147460.007683358 24.22417582 Hyper-methylated PCa|NT DMRs chrX 129067840129068339 0.000118733 −23.55132275 Hypo-methylated PCa|NT DMRs chrX129113280 129114164 0.000652011 20.30392157 Hyper-methylated PCa|NT DMRschrX 130192230 130192579 4.00E−07 28.06738095 Hyper-methylated PCa|NTDMRs chrX 130202141 130217941 2.26E−15 25.05962733 Hyper-methylatedPCa|NT DMRs chrX 132056790 132091788 1.60E−19 25.74152381Hyper-methylated PCa|NT DMRs chrX 133678817 133679201 2.00E−0722.42142857 Hyper-methylated PCa|NT DMRs chrX 134124839 1341250060.007560755 27.00595238 Hyper-methylated PCa|NT DMRs chrX 134556267134556750 0.000172237 33.73968254 Hyper-methylated PCa|NT DMRs chrX136515424 136601303 1.76E−06 −37.90039683 Hypo-methylated PCa|NT DMRschrX 142774516 142826712 4.83E−06 −34.49107143 Hypo-methylated PCa|NTDMRs chrX 143313497 143314640 2.01E−07 −29.95666667 Hypo-methylatedPCa|NT DMRs chrX 143477542 144599111 1.68E−17 −33.58040816Hypo-methylated PCa|NT DMRs chrX 144713810 144764865 0.001241245−34.55185185 Hypo-methylated PCa|NT DMRs chrX 144970738 1452809345.78E−09 −31.74571429 Hypo-methylated PCa|NT DMRs chrX 145340421145460969 0.000205174 −36.76190476 Hypo-methylated PCa|NT DMRs chrX149936797 149936898 0.005513661 28.37346939 Hyper-methylated PCa|NT DMRschrX 150134835 150140167 0.005685503 −29.69246032 Hypo-methylated PCa|NTDMRs chrX 150144407 150144825 2.37E−06 33.35914787 Hyper-methylatedPCa|NT DMRs chrX 151143026 151143469 1.49E−06 20.75569358Hyper-methylated PCa|NT DMRs chrX 152023843 152066309 0.00110492229.37868481 Hyper-methylated PCa|NT DMRs chrX 152753215 1527541640.001175696 −24.5789916 Hypo-methylated PCa|NT DMRs chrX 152830128152830220 0.005968871 −25.3952381 Hypo-methylated PCa|NT DMRs chrX152861426 152863799 0.000377317 −42.33630952 Hypo-methylated PCa|NT DMRschrX 152876646 152878070 0.001397404 −28.41269841 Hypo-methylated PCa|NTDMRs chrX 152942395 152950833 0.00024701  28.41269841 Hyper-methylatedPCa|NT DMRs chrX 152987722 152987887 0.005968871 −36.8 Hypo-methylatedPCa|NT DMRs chrX 153044149 153046538 0.006173852 −20.45026455Hypo-methylated PCa|NT DMRs chrX 153096570 153097110 0.00523391821.9997619 Hyper-methylated PCa|NT DMRs chrX 153135670 1531362570.00064571  −36.1585034 Hypo-methylated PCa|NT DMRs chrX 153186909153187137 1.31E−06 −30.93439153 Hypo-methylated PCa|NT DMRs chrX153210313 153210375 0.00064571  43.59183673 Hyper-methylated PCa|NT DMRschrX 153247228 153249478 1.62E−05 49.55380952 Hyper-methylated PCa|NTDMRs chrX 153265046 153265306 0.004350823 −22.02380952 Hypo-methylatedPCa|NT DMRs chrX 153279521 153284103 0.004900079 −20.1827381Hypo-methylated PCa|NT DMRs chrX 153389029 153391568 0.00025613721.46071429 Hyper-methylated PCa|NT DMRs chrX 153402520 1534025700.001896858 20.67619048 Hyper-methylated PCa|NT DMRs chrX 153740124153740334 0.003093471 25.22190476 Hyper-methylated PCa|NT DMRs chrX153764058 153769683 0.000440265 −35.14077381 Hypo-methylated PCa|NT DMRschrX 153885985 153886696 5.19E−07 −23.46996337 Hypo-methylated PCa|NTDMRs chrX 154563531 154842269 0.002643508 36.75119048 Hyper-methylatedPCa|NT DMRs chrY 13463589 13464487 1.24E−05 −20.29328231 Hypo-methylatedPCa|NT DMRs chrY 13471045 13471610 4.38E−05 −27.97397959 Hypo-methylatedPCa|NT DMRs chrY 13489568 13489881 0.002879573 −23.45185185Hypo-methylated PCa|NT DMRs chrY 16539933 16619252 4.62E−05 −30.31936508Hypo-methylated PCa|NT DMRs chrY 18255052 18958865 3.33E−07 −31.59047619Hypo-methylated PCa|NT DMRs chrY 23111562 23112013 0.001969641−24.47857143 Hypo-methylated PCa|NT DMRs chrY 23596847 236094250.005118278 −21.12539683 Hypo-methylated PCa|NT DMRs chr1 848739 8494140.003348504 −22.17517869 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1870425 871654 2.16E−11 −29.212915 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 984022 984429 1.97E−07 −28.24485099 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 986842 987058 8.37E−09 −29.75584795 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 1007056 1007879 4.16E−12 −21.44892339Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 1133030 1133217 7.23E−06−22.11199295 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 1221147 12218329.13E−07 −26.34678363 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 12341251235195 0.000307123 −25.45329067 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 1337686 1337736 0.001694183 30.2672619 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 1353533 1355640 3.31E−14 −21.34642492Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 1373372 1373611 0.00475084424.83164766 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 1397525 13983491.17E−08 −40.50736315 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 15384871540691 0.000921835 −20.25311943 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 1567269 1567869 9.55E−15 −22.41288022 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 1591256 1591305 0.005737741 −20.48202614Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 1879001 1887524 0.008866725−21.28134675 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 1896556 18972841.60E−06 −23.24402267 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 19408531946741 0.003652661 −24.92564745 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 1951348 1954793 0.000169597 −21.50611664 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 1986028 1986276 5.27E−10 37.39543706Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 2036222 2036833 2.94E−06−44.17522974 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 2110845 21113280.003484081 −24.96863728 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12171063 2171717 0.005899637 24.91915094 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 2259879 2264759 1.48E−09 −24.76411681 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 2286452 2287295 6.68E−05 −20.46129212Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 2307117 2308440 6.29E−06−26.5734858 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 2309867 23100859.68E−10 −41.35994152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 23591672360307 1.17E−08 −21.65369807 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12362827 2366638 1.35E−14 −23.81797005 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 2366802 2372772 2.35E−08 −21.960457 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 2379601 2384305 6.61E−05 −24.46729379Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 2400991 2403836 0.001402859−27.28723971 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 2472413 24725861.76E−08 −21.84329825 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 25253612525577 0.008510472 −22.63391813 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 2706076 2706299 5.50E−05 24.22001762 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 2706411 2706476 0.000200845 27.17Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 2780321 2780506 0.00220195225.4046841 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 3085851 30906281.17E−14 −30.39803271 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 30922223096495 4.07E−05 −23.88819386 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13375025 3377669 3.51E−09 20.26826225 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 3388196 3390288 1.55E−05 21.22200237 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 3418019 3418479 0.000287903 −25.90647773Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 3421599 3422096 8.77E−08−29.39494815 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 3438072 34382835.75E−05 −28.58918129 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 34596433460268 9.31E−09 30.116911 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13463918 3464395 0.009822962 −22.20619681 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 3506818 3507206 8.98E−08 −40.35016571 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 3511792 3512244 4.25E−06 −21.72374192Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 3607143 3607222 0.003525992−30.69110839 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 3615128 36155247.47E−05 −26.03563074 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 36437973644749 4.65E−10 22.24736136 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13669813 3672443 0.000400293 −23.86206924 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 3679587 3684215 0.000221105 −21.02997494 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 4773064 4774126 5.17E−06 −24.5404572Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 5710356 5710691 0.001694183−29.8079148 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 5806929 58069810.001694183 −26.20653021 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16108507 6109003 0.009274146 −21.65037594 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 6221905 6230389 0.000113382 21.93720158 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 6296631 6296737 0.000241282 22.67964912Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 6304286 6304652 0.00288530822.36546053 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 6330487 63318645.17E−06 −39.57825625 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 64383506438500 0.009458442 −35.69498747 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 6445632 6445894 0.000176134 −46.18077485 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 6533161 6534154 6.22E−12 −40.84144832Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 6647655 6647751 0.000176134−22.19061195 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 6767641 67723180.003113626 −40.2729439 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16775316 6778626 0.009285355 −22.56168746 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 6807362 6817716 0.001012154 −28.38100644 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 7710979 7711108 0.000549237 −36.08011696Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 7945526 7945651 0.00169418323.27738791 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 8014086 80146241.10E−23 23.59429747 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 91304359131611 0.005737741 30.17114293 Hyper-methylated NEPC|CRPC-Adeno DMRschr1 9376010 9376264 5.50E−05 22.04482619 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 9501650 9502882 0.000176134 −45.19445704Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 9653880 9654098 0.00367696 −23.84354067 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 9887816 98960890.000282282 −26.58046784 Hypo-methylated NEPC|CRPC-Adeno DMRs chr110095202 10095654 0.001694183 −34.18810916 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 10975754 10975909 0.001694183 −33.5974537Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 11008316 11008961 5.36E−06−28.83703704 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 11435636 114363910.005737741 −43.7377193 Hypo-methylated NEPC|CRPC-Adeno DMRs chr111696006 11708325 0.00222033  39.27577399 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 11713238 11713392 0.004750844 −20.30618212Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 12113627 12123863 8.46E−0727.11107314 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 13883902 138940190.001694183 −51.90935673 Hypo-methylated NEPC|CRPC-Adeno DMRs chr113914270 13970164 0.006597219 −35.58503899 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 14027548 14027604 0.001694183 36.17026942Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 15276468 15276617 0.000549237−28.97387288 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 15438936 154391520.002094266 −20.35746774 Hypo-methylated NEPC|CRPC-Adeno DMRs chr115653145 15664647 0.000224358 −31.87467382 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 15911071 15911703 3.12E−12 −21.642335Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 16065023 16065205 0.00222033 −22.90357143 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 16533719 165346830.001808548 −27.31392544 Hypo-methylated NEPC|CRPC-Adeno DMRs chr117019941 17026803 1.37E−09 23.49319888 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 17186315 17186349 0.001694183 32.24912281 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 17306624 17307241 7.41E−07 −21.71732572Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 17475708 17475923 1.94E−0620.49690446 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 17488505 174896490.000484821 −40.41052632 Hypo-methylated NEPC|CRPC-Adeno DMRs chr118032815 18033409 0.004750844 −35.66290727 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 18606212 18606375 0.000184724 −42.46725146Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 18808325 18812892 5.38E−38−53.2543711 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 19030039 190388130.008187764 −25.93745817 Hypo-methylated NEPC|CRPC-Adeno DMRs chr119057778 19121141 9.16E−06 −21.45587537 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 19186670 19194804 8.35E−06 −31.62631579 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 19258538 19258624 0.001694183 −35.89583333Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 19377393 19384828 2.04E−05−26.55734858 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 19664237 196644960.000253274 −37.5188229 Hypo-methylated NEPC|CRPC-Adeno DMRs chr119676470 19686501 6.32E−08 −30.33183761 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 19722252 19732801 2.91E−05 −32.87718634 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 20140860 20142765 2.92E−14 −47.89945554Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 20311214 20396751 0.002362173−20.34243181 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 20880205 208802410.000100851 −24.98421053 Hypo-methylated NEPC|CRPC-Adeno DMRs chr121953521 21960152 0.002592833 26.54858942 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 22141031 22141342 5.77E−06 21.17186626Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 22194316 22195653 1.70E−05−41.16979323 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 22240923 222418394.34E−06 −42.69576883 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 2226001922260752 0.008187764 −25.47755496 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 22511798 22511964 0.000926684 −23.36574561 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 22854360 22854409 0.001532655 −35.35723756Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 22920087 22920170 0.000176134−20.84671053 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 24463665 244697920.005899637 −21.08105263 Hypo-methylated NEPC|CRPC-Adeno DMRs chr125231369 25233024 0.000324528 −25.20504386 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 25522358 25525724 0.002885308 −26.22349125Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 27845945 27846128 0.003327791−41.09010255 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 27961638 279617400.000340762 21.18438596 Hyper-methylated NEPC|CRPC-Adeno DMRs chr128871410 28871634 0.002976353 −21.90300752 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 28918526 28919527 3.26E−13 −22.35819416Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 29449832 29449957 0.000184724−21.13898635 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 30815151 308156940.000731112 26.74130781 Hyper-methylated NEPC|CRPC-Adeno DMRs chr132054406 32054842 3.30E−13 −25.87491021 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 32180228 32180414 1.98E−05 28.07332533 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 32252165 32252427 5.50E−05 −53.69590643Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 32714121 32714183 0.000100851−34.51866029 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 34082982 340831960.002094266 −30.15178687 Hypo-methylated NEPC|CRPC-Adeno DMRs chr135297541 35311446 0.000586307 −22.78102723 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 36549282 36549982 7.60E−14 −27.36307949Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 37866213 37866383 0.000549237−39.09383754 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 38065716 380961440.000888   −32.73975298 Hypo-methylated NEPC|CRPC-Adeno DMRs chr138113125 38133342 0.000397177 −22.11663861 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 38230321 38230376 0.00041315  −25.39824561Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 38461600 38461897 4.39E−13−35.85376096 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 38513525 385136702.46E−05 28.50680387 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 3895579739012628 3.76E−05 −21.94345422 Hypo-methylated NEPC|CRPC-Adeno DMRs chr139206321 39213090 0.004051703 −22.63904423 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 40236936 40237158 2.01E−08 35.61952492Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 40421862 40426304 4.50E−05−23.77412281 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 41486102 414862565.99E−05 −30.21579992 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 4185711841857300 0.001694183 −40.09153439 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 41967415 41967600 1.70E−05 −25.39307018 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 44889376 44889443 0.000549237 29.21578947Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 45656666 45657053 5.01E−05−40.075 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 45768445 457685390.003113626 −36.76111111 Hypo-methylated NEPC|CRPC-Adeno DMRs chr146956572 46959593 2.62E−07 23.52855116 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 47009603 47013241 2.16E−06 31.64829624 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 48237520 48241090 0.00017321  −25.8764411Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 50741384 50741571 0.000176134−22.96381579 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 51763251 517633760.00222033  −22.34802632 Hypo-methylated NEPC|CRPC-Adeno DMRs chr152832763 52832874 0.000549237 −29.43289474 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 53785219 53785688 0.000549237 −31.92932331Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 53841347 53842853 9.76E−12−50.50255221 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 54072597 540726380.001694183 −36.6622807 Hypo-methylated NEPC|CRPC-Adeno DMRs chr154739154 54739199 0.000549237 −21.88703008 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 54808693 54808777 5.50E−05 −46.87089019Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 55075333 55089183 0.001310325−24.9670668 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 55461536 554629900.001310325 25.88825911 Hyper-methylated NEPC|CRPC-Adeno DMRs chr155525673 55530145 2.34E−07 −28.42802802 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 65431241 65431341 0.00041315  −23.72631579 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 65731412 65731782 7.63E−11 33.9382758Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 67773363 67773701 2.60E−17−20.3537604 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 68219766 682199610.004750844 −24.62124499 Hypo-methylated NEPC|CRPC-Adeno DMRs chr168281422 68281687 0.001694183 30.75108359 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 70598406 70598450 0.005737741 24.49444444Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 79472483 79472537 0.00169418320.78752437 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 81564805 815650000.006785531 −20.41785453 Hypo-methylated NEPC|CRPC-Adeno DMRs chr181869776 81869957 0.001694183 41.56666667 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 85527430 85527873 0.003113626 −21.43333333Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 88928458 88928533 4.94E−0528.47192982 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 88932816 889331041.92E−07 −36.25618461 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 8901694289103353 0.002376793 −26.64570785 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 90075469 90076027 0.003113626 −24.3662424 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 90099695 90099891 0.001694183 −20.95272904Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 91182462 91185367 1.56E−2428.6925175 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 91190946 911909850.003525992 29.62017544 Hyper-methylated NEPC|CRPC-Adeno DMRs chr194566449 94568090 0.000542154 24.67751196 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 98510937 98511106 4.76E−10 34.227618Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 99470311 99470639 3.73E−1127.29306861 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 103215035103268330 5.50E−05 −30.66237817 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 106675550 106926243 0.00222033  −20.93739427 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 106982881 107050285 1.60E−06 −26.43186671Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 107536775 1075562490.002976353 −27.24135338 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1110883147 110884779 0.000128281 −21.83186449 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 111218002 111218083 0.001802623 20.78788638Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 112282928 112283151 2.16E−12−21.33957115 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 114654380114654573 0.000549237 −28.91853654 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 116197674 116197814 0.000549237 40.82951128 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 144994610 144994895 0.000348917 −24.56340852Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 145514968 1455151650.000200845 −32.19906433 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1149333101 149333199 0.0001635  20.4851143 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 150254716 150255542 8.64E−11 −20.22602339Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 151105124 1511051810.005737741 20.08508772 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1151369847 151371481 0.007379618 −24.81473684 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 153505362 153539059 1.50E−07 −23.35227554Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 153748967 1537492130.005239183 −39.21106934 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1153768106 153768185 4.74E−05 −22.12099947 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 154259925 154273412 5.50E−05 −26.2675141Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 154386862 1543905050.00217795  26.50596491 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1154474108 154474751 2.73E−35 −21.6292707 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 154840396 154841951 8.52E−07 −37.19461812 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 154978298 154986712 0.003327791 25.91245079Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 155103222 1551040030.001694183 48.74731682 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1155220184 155220232 5.17E−06 23.78229665 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 155243891 155243940 0.001694183 −33.39105392Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 155262968 1552631010.005737741 −27.63859649 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1155912449 155915866 0.000890838 −31.15620055 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 156146474 156146805 0.00041315  −22.11580476Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 156379461 1563902520.000581135 25.14437135 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1156390706 156390914 1.11E−06 −21.13623239 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 156593608 156593887 1.49E−07 −26.00902446Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 156646419 156646946 5.72E−09−20.03551302 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 156890278156890488 1.45E−06 −22.45786894 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 158150797 158151205 8.34E−06 21.72869609 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 160094101 160104377 0.001125639 −27.00631579Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 161448889 1614717660.001802623 −42.54278343 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1161592118 161674114 0.000484821 −25.12484532 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 167408692 167409105 1.90E−12 −20.35913351Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 167458187 1674712830.000209051 −29.41777455 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1167881539 167898361 0.001012154 32.31248956 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 168054725 168054875 0.000549237 34.55829771Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 169707660 1697098620.003327791 −20.90998882 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1170883644 171350978 5.08E−08 −30.69585507 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 171625172 171640038 0.0001415  −20.49778488Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 173491184 1734912860.000549237 −21.71888545 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1177056919 177113360 0.001802623 27.68604845 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 177183426 177219623 1.29E−09 22.82347189Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 177247737 177716521 3.00E−0821.83378655 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 179388196179497888 3.58E−07 −32.18985507 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 179713513 179740376 3.74E−05 25.3960944 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 179742849 179743483 0.001694183 −23.67641326Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 180204579 180204974 2.19E−0821.53567406 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 181452972181453056 1.55E−06 26.27807018 Hyper-methylated NEPC|CRPC-Adeno DMRschr1 183155057 183169382 2.08E−08 −24.03792361 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 186889118 186949281 0.001642117 −23.16023392Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 188810539 1889321100.00158762  21.05204678 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1197879662 197879802 1.55E−06 31.09429825 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 197887955 197890813 1.21E−06 23.51822284Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 200992306 200992549 1.55E−08−22.36142788 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 201096142201096334 4.74E−05 −37.35956558 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 204827934 204839816 0.00060921  −20.76413829 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 205011154 205012570 9.27E−10 −27.80571518Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 205424899 2054249730.000318709 20.82020202 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1206837257 206837409 0.000953892 −27.04917763 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 207842658 207843013 1.84E−08 32.73795723Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 208202787 2082028660.001694183 −37.34385965 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1208255452 208255712 1.70E−05 −28.36458333 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 209548645 209785461 3.55E−06 −28.7670178Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 209803066 2098031750.000176134 −32.63460505 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1209920990 209921100 0.003113626 30.05701754 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 210111212 210111944 2.63E−25 32.60420009Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 210426095 210460305 5.75E−05−21.41190415 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 210526652210703855 0.005375697 −22.98817755 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 210806711 210825862 0.002976353 −37.24840252 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 213124496 213124946 1.06E−08 −21.28849903Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 215256112 215256635 8.27E−2625.93420627 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 218098336218098399 1.09E−07 27.77977839 Hyper-methylated NEPC|CRPC-Adeno DMRschr1 220636185 220636483 0.000101637 −35.45906433 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 220826507 220826565 0.001694183 −22.90150376Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 224372513 2243828340.00678631  25.86671335 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1225629948 225631281 0.001012154 −28.46495177 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 226003504 226003849 0.000303685 −27.39051332Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 226075069 2260757670.002667178 21.49674536 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1226090654 226099251 0.000154511 26.70270853 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 226126979 226127446 2.23E−05 22.66344507Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 228261545 2282636250.002376793 −33.74621838 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1228463266 228463571 3.68E−07 −24.47091413 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 228492413 228502871 6.49E−06 −21.71374269Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 228504625 2285063570.000763207 −20.34883041 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1229071337 229071545 0.001694183 −20.70779727 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 229506415 229517095 0.009274146 −27.25232456Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 229567994 229569644 9.72E−1726.89497624 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 229570004229570597 1.09E−08 −25.87887427 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 230266192 230266405 0.000549237 −47.26333691 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 230436736 230436927 0.000200845 −24.14106725Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 230849738 2308502120.003087144 20.44572471 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1231299496 231299678 3.71E−11 25.4944332 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 231826172 231829667 3.72E−06 −29.1713835 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 232463565 232463621 0.000832692 −27.09013158Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 234831584 2348453830.002094266 −45.37348928 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1234908226 234908382 0.000549237 −22.76853741 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 236306856 236308302 0.004693517 22.85116846Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 236849487 236850241 7.80E−2527.84412585 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 236857562236908311 1.30E−07 −36.01468551 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 237034318 237052704 0.001694183 22.39610136 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 237122944 237195447 7.25E−10 −42.84443736Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 237205222 237206562 4.39E−3225.56940787 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 237212338237832931 7.55E−31 −40.21227117 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 237832994 237959047 0.001802623 −21.93031537 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 239560828 239931256 7.16E−11 −28.97652329Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 242633393 2426740720.002718013 −20.45013645 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1243646523 243647205 0.000876403 25.17284516 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 244106446 244189663 0.002094266 −22.74063629Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 244394659 2443953660.001694183 −33.49080954 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1245375798 245376090 0.00041315  −28.24485055 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 245397978 245398214 5.36E−06 −43.2464425Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 246311010 2463113010.000581135 −27.66183297 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1246958344 246958526 0.000324528 −35.9125 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 247654811 247694461 4.08E−22 22.6762879 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr2 558070 565808 0.005899637 −20.64210483Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 574111 575374 0.004750844−31.08940058 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 587269 5948930.000153872 −20.88201546 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2946912 947141 0.003223004 20.12491676 Hyper-methylated NEPC|CRPC-AdenoDMRs chr2 1229230 1229292 0.001694183 −22.63308271 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 3704747 3704865 0.000176134 −33.80723684Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 5833641 5834110 6.46E−0822.55885167 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 7497762 75186830.006785531 −38.46185516 Hypo-methylated NEPC|CRPC-Adeno DMRs chr28793681 8797420 0.001802623 −26.99752954 Hypo-methylated NEPC|CRPC-AdenoDMRs chr2 9324021 9327608 4.29E−06 21.55963542 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr2 9513262 9513322 0.001694183 −30.67050961Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 10170502 10170669 0.000176134−33.37368421 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 10302076 103031450.000324528 −35.79671053 Hypo-methylated NEPC|CRPC-Adeno DMRs chr210899354 10899571 0.002094266 28.30116959 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr2 11925058 11925198 0.00324027  24.70484893Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 15936602 15940517 0.004750844−21.02404971 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 16153331 161543661.69E−10 −23.34380604 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 1651131916578454 0.000101574 −20.5190639 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 17421705 17524336 0.004750844 −29.73421053 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 20548540 20548615 0.000176134 −20.26578947Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 21056358 21101016 0.006847068−34.48125522 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 21266324 212670308.36E−05 23.78680574 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 2316719123167321 0.005737741 −21.97819201 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 23747138 23757045 5.04E−05 −30.68748173 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 23770125 23777570 1.50E−07 −34.75308642Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 23786468 23788930 0.002927544−21.08622482 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 25285553 252999300.000667554 −42.10759288 Hypo-methylated NEPC|CRPC-Adeno DMRs chr225452256 25459585 7.36E−07 −30.8897254 Hypo-methylated NEPC|CRPC-AdenoDMRs chr2 26407468 26408214 1.64E−30 −25.46531281 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 26681020 26681087 0.001694183 −25.86666667Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 26763381 26766237 0.000324528−25.56650219 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 27165508 271655440.000721524 21.47744361 Hyper-methylated NEPC|CRPC-Adeno DMRs chr227473163 27473238 5.36E−06 33.97272348 Hyper-methylated NEPC|CRPC-AdenoDMRs chr2 28907245 28907308 0.000549237 −31.74135338 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 29192790 29213525 2.76E−05 −22.80890688Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 29232329 29273929 3.07E−08−23.33551665 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 29285106 293201672.82E−06 −21.43834858 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 2943830729448419 0.002576454 −25.66365272 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 29563311 29722569 0.00060921  −27.92785804 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 30158882 30328159 1.99E−06 −23.881619Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 31231690 31231895 0.001549499−25.8625 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 32483098 324931841.46E−05 −24.73126198 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 3383596133979130 2.26E−06 −21.8558705 Hypo-methylated NEPC|CRPC-Adeno DMRs chr234367845 34373093 0.000549237 −26.02518551 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 34615317 34615366 0.004750844 −21.01269841Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 37571704 37572366 2.01E−18−24.71985052 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 39471098 394711480.00041315  −29.06169973 Hypo-methylated NEPC|CRPC-Adeno DMRs chr243038039 43038270 8.97E−08 −20.15104428 Hypo-methylated NEPC|CRPC-AdenoDMRs chr2 43327732 43328756 6.98E−17 −27.55103368 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 44058915 44059267 6.05E−10 −23.58462578Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 47877314 47904072 0.003348504−22.79426344 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 54010084 540102950.001694183 26.45233918 Hyper-methylated NEPC|CRPC-Adeno DMRs chr254685003 54685052 0.001694183 −24.97791005 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 58654887 58655598 4.11E−07 21.53544974Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 62221214 62221247 0.00573774120.79824561 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 65217164 652177420.001666853 −32.39952153 Hypo-methylated NEPC|CRPC-Adeno DMRs chr266804656 66810625 3.38E−08 31.89104224 Hyper-methylated NEPC|CRPC-AdenoDMRs chr2 73301681 73308018 1.98E−05 23.24652979 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 74006134 74006203 0.000549237 −23.42011278Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 77961147 77962203 5.50E−0520.36482231 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 79918776 799723270.000549237 −26.724914 Hypo-methylated NEPC|CRPC-Adeno DMRs chr180519910 80530588 6.32E−08 28.74203873 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 80531759 80531809 1.55E−06 20.3504386 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 81424285 81694490 4.01E−05 −24.8101957Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 81694557 81850017 7.45E−10−28.2601711 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 84770004 850431843.10E−06 −24.46461988 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 8701591187017295 1.53E−15 24.99944686 Hyper-methylated NEPC|CRPC-Adeno DMRs chr188305001 88305825 0.003525992 −20.39278752 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 88583923 88583990 0.001545937 23.94371345Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 88650149 88650678 0.00230924125.4040499 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 89064665 890647629.82E−05 21.048583 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 9175786191757982 8.87E−06 27.79373782 Hyper-methylated NEPC|CRPC-Adeno DMRs chr193018365 92028390 0.001012154 27.52294339 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 95541756 95584028 0.005532731 −23.90266734Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 95935759 95942618 0.00130678921.97767067 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 96053259 960553759.74E−06 −25.70678298 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 9635735096421972 0.007136365 −26.93834586 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 99531119 99531917 5.36E−06 −38.45979532 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 100863650 100864133 0.001642117 −20.34782326Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 101726347 1017466740.00450545  −27.78424493 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1102803560 102804460 6.88E−06 −29.1251075 Hypo-methylated NEPC|CRPC-AdenoDMRs chr1 102867728 102867822 5.17E−06 −22.90435977 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 105460250 105461169 1.70E−06 23.17106696Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 105469590 1054713630.002023694 24.07688209 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1105472598 105472739 2.60E−09 27.4558114 Hyper-methylated NEPC|CRPC-AdenoDMRs chr1 105474399 105474451 0.000549237 22.70290011 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 107103708 107104119 4.20E−09 −21.36352087Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 108602916 108603122 1.71E−0925.06372442 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 109523216109524435 4.66E−05 −28.38012914 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 110873010 110873170 0.001221669 −26.74025341 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 111957727 111958255 0.000926684 −45.48011174Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 113992763 113994167 8.00E−1331.37393241 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 114359410114360124 4.72E−07 28.17447793 Hyper-methylated NEPC|CRPC-Adeno DMRschr1 115918770 115919993 7.64E−28 25.05568087 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 119599142 119599175 5.50E−05 −27.6502924Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 119601016 119602645 9.09E−05−21.95368978 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 119606289119606544 0.009167638 26.56572927 Hyper-methylated NEPC|CRPC-Adeno DMRschr1 119610407 119610425 0.000303685 20.69532164 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 119915117 119915902 6.00E−08 22.09453582Hyper-methylated NEPC|CRPC-Adeno DMRs chr1 120452147 1204523210.000488426 −29.53157895 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1120825589 120826561 0.005239183 −28.72839506 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 121071218 121071615 2.14E−06 −20.7802562Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 121153634 1211537910.003348504 −40.20637589 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1121200581 121200763 2.64E−09 21.24714515 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr1 121223604 121223892 7.90E−06 −40.19098184Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 121238158 1212442680.001549499 26.48457602 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1121580735 121585855 1.47E−05 −21.33102312 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 121604037 121605767 5.50E−05 −36.93508772Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 121644936 121645587 7.96E−07−33.71186475 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 121846490121847867 0.007136365 −25.76876566 Hypo-methylated NEPC|CRPC-Adeno DMRschr1 128177475 128180539 0.005557404 −21.7417154 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 128366766 128370333 0.00324027  −20.84426907Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 128411111 1284120030.001689936 −22.42920649 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1128438863 128439315 2.69E−07 −24.72315262 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 128616678 128616767 0.000549237 −39.66474221Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 129019404 1290195340.003525992 −42.77777778 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1129063081 129063273 0.000581135 −31.43997248 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 129122084 129123431 5.75E−05 −28.03508772Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 129198482 1291988250.004750844 −30.19461644 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1129225176 129244012 0.00302923  −21.93509816 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 129260154 129337554 2.33E−05 −20.19219088Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 129352316 1293611800.000193859 −22.05175609 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1129435812 129491399 0.000246327 −23.97108751 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr1 129528148 129540816 0.005737741 −21.41918686Hypo-methylated NEPC|CRPC-Adeno DMRs chr1 130076619 130344545 1.50E−07−34.59962519 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 130408104130496813 8.93E−07 −28.94061341 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 130510355 130515318 0.000101637 −26.40830562 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 130661361 130671156 5.38E−06 −22.21064621Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 131060249 1310738200.000337664 −32.73859649 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2131514052 131514704 9.21E−06 −20.47162023 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 131936509 131968179 3.43E−06 −22.58689426Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 132251816 1322521330.000176134 −29.04024338 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2132293756 132391658 4.03E−10 −33.02168439 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 132877035 132944869 0.004750844 −31.15037594Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 133062272 1330624250.000200845 35.97508772 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2133246899 133247159 4.14E−08 36.7942792 Hyper-methylated NEPC|CRPC-AdenoDMRs chr2 134785429 134785660 0.001012154 25.96165414 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr2 143460125 144172370 4.88E−06 −25.82494081Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 153192734 153192875 1.22E−05−20.88712682 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 161052000161125859 0.008916498 −24.86994901 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 162838347 162838416 0.001694183 −25.95238095 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 163299224 163622381 0.005456645 21.47698413Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 163882749 163883094 1.70E−0522.68208333 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 170219995170220470 2.03E−06 −20.49118095 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 175205481 175205751 2.71E−06 20.63542189 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr2 179278075 179278593 8.97E−08 −21.46412787Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 182546475 182547973 1.80E−0720.57561404 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 186603546186603618 0.000549237 24.79033298 Hyper-methylated NEPC|CRPC-Adeno DMRschr2 188733953 188734511 0.009274146 −27.73866959 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 197379889 197380122 0.000176134 −42.02678019Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 198315420 1983154860.000549237 −25.87819549 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2206547479 206547524 0.000192248 −21.66059942 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 207115220 207115508 0.000291618 20.64307992Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 207521644 2075632090.004750844 −20.70701754 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2207929328 207972442 0.000176134 −49.82702851 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 217850623 217850810 0.001694183 −33.93518519Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 219748326 219748628 5.23E−13−23.12146814 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 219749016219749103 0.005737741 −26.24414775 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 220270066 220283866 3.22E−16 25.12400617 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr2 220316324 220317803 0.000102271 −22.15006579Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 220397136 220397259 5.75E−05−29.27138397 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 220439493220439633 1.70E−05 −27.35157895 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 220509463 220509832 2.85E−10 −45.58795322 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 222826407 222826513 0.000176134 −32.00328947Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 224477834 224478322 5.01E−05−24.43060429 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 227898189227898378 0.000549237 24.99906752 Hyper-methylated NEPC|CRPC-Adeno DMRschr2 232290776 232291013 0.003932932 −27.77493502 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 232536414 232545414 2.22E−11 −47.43532003Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 233306667 2333069020.009458442 −25.75048733 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2233464792 233464920 0.009458442 −23.64473684 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 233888552 233916226 5.61E−05 −20.08187749Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 234079048 2340836100.000153872 −21.05410401 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2234699500 234704770 4.00E−06 −24.53621233 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 235237250 235237950 0.001694183 −34.99074074Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 235737595 2357401180.000716333 −24.57805011 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2235941822 235949479 0.000104758 −27.16893303 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 236486227 236486417 0.000549237 −38.75005669Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 236528752 2365290120.002927544 −25.12469136 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2237501472 237501628 0.001694183 −31.77022059 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 237727216 237727409 0.001694183 28.49338624Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 238404105 238404446 1.70E−0524.31431373 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 238472648238472726 0.003327791 21.96388889 Hyper-methylated NEPC|CRPC-Adeno DMRschr2 238610221 238612278 0.000549237 −28.16165633 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 238794510 238794838 4.65E−07 −38.12277526Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 238832403 238832515 6.03E−0627.51333333 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 238856011238865307 1.73E−08 34.37750043 Hyper-methylated NEPC|CRPC-Adeno DMRschr2 239039611 239040086 1.41E−08 −27.08506006 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 239048258 239048449 2.07E−08 30.3332265Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 239066848 239067031 3.15E−05−26.96352941 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 239129499239130134 9.74E−06 −27.34281674 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 239147433 239148142 5.07E−08 −24.47076114 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 239149756 239149938 0.000553171 −20.06018519Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 239323913 2393242110.003113626 −38.39738173 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2239413150 239413386 3.06E−06 −37.48166667 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 239453395 239467821 0.000104758 −32.08421717Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 239487105 239612308 6.61E−09−20.68710654 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 239756501239757623 6.64E−11 26.80913042 Hyper-methylated NEPC|CRPC-Adeno DMRschr2 239780522 239800796 0.000218789 −21.59291472 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 239872281 239907659 3.16E−06 −22.67556307Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 239907717 239907900 1.40E−06−25.37291667 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 239907945239908470 0.000184724 −21.88547308 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 240002663 240003506 2.08E−05 −20.58040936 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 240044530 240044797 0.000303685 −25.20130719Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 240271689 2402717860.001694183 −27.36111111 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2240386993 240387067 0.000832692 −29.325 Hypo-methylated NEPC|CRPC-AdenoDMRs chr2 241176159 241185506 1.07E−06 −25.27123216 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 241232629 241233216 1.41E−05 −50.57723797Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 241393816 241397544 1.00E−1238.18395326 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2 241408285241408720 0.000440683 −24.19166965 Hypo-methylated NEPC|CRPC-Adeno DMRschr2 241772069 241772103 0.003525992 −27.11111111 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 241830975 241831203 0.000549237 −31.47376775Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 242139533 2421396160.000581135 34.62828947 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2242355688 242356453 0.000711935 −27.31578947 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr2 242481481 242481937 2.41E−07 −30.10079745Hypo-methylated NEPC|CRPC-Adeno DMRs chr2 242812420 242812661 1.57E−06−25.60897266 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 463049 5134600.001694183 −43.68333333 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3577629 577844 3.06E−06 26.15192224 Hyper-methylated NEPC|CRPC-Adeno DMRschr3 2125621 2125739 0.001694183 −29.78289474 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 2211250 2395440 2.96E−08 −24.9629741Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 2547773 2771394 0.000154411−25.14076933 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 2846718 31264224.31E−10 −23.08686935 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 32229763761172 1.85E−05 −24.72503578 Hypo-methylated NEPC|CRPC-Adeno DMRs chr34061898 4287901 4.74E−05 −29.32643737 Hypo-methylated NEPC|CRPC-AdenoDMRs chr3 4650559 4701228 0.001980589 −21.43587891 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 9595319 9595668 2.46E−06 21.1862008Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 9957450 9957637 1.77E−06−23.56558062 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 10363228 103632920.00222033  23.30555556 Hyper-methylated NEPC|CRPC-Adeno DMRs chr310877364 10928399 6.82E−05 −30.43403872 Hypo-methylated NEPC|CRPC-AdenoDMRs chr3 11046887 11072823 2.68E−07 −26.94088074 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 11112978 11133754 2.64E−05 −23.11886152Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 11138548 11168621 2.58E−05−25.26545015 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 12672954 126730230.000549237 −43.48517126 Hypo-methylated NEPC|CRPC-Adeno DMRs chr313008783 13009257 2.76E−21 35.76399768 Hyper-methylated NEPC|CRPC-AdenoDMRs chr3 13060941 13069923 2.23E−06 −28.9748894 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 13114303 13114344 0.003113626 −21.60350877Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 13245569 13246093 2.81E−0632.3879257 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 13367277 133673570.000549237 −22.96616541 Hypo-methylated NEPC|CRPC-Adeno DMRs chr313560180 13569838 0.007136365 −29.05864662 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 14445043 14445162 0.001694183 −27.02280702Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 14556022 14559856 0.000953892−28.0063274 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 14806535 148465341.53E−09 −22.37547218 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 1487777114910141 0.000224358 −24.82001462 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 15160267 15204210 0.000538714 22.84587069 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 18485142 18485766 9.36E−16 −22.70118134Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 22413885 22414340 3.82E−1735.11866472 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 24780720 248555650.000542154 −22.05241893 Hypo-methylated NEPC|CRPC-Adeno DMRs chr325109412 25348735 1.11E−08 −22.19636591 Hypo-methylated NEPC|CRPC-AdenoDMRs chr3 25928241 26608348 6.92E−10 −31.8026437 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 26664116 26665533 7.94E−17 33.53493626Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 26666972 27168486 3.44E−06−27.71704134 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 27944115 282414550.002692265 −21.07048872 Hypo-methylated NEPC|CRPC-Adeno DMRs chr329185724 29221824 0.000168572 −20.60233811 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 38070605 38070935 1.85E−05 22.99612442Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 38583417 38584178 0.001545937−30.12396733 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 42304914 423053071.54E−10 −24.6642161 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 4274374442743829 0.007136365 −20.08195489 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 46274813 46394598 5.23E−05 −24.18838306 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 48690417 48694482 2.85E−16 24.86272825Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 48698457 48699857 6.62E−0726.74565037 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 49381502 493832170.002094266 21.87965011 Hyper-methylated NEPC|CRPC-Adeno DMRs chr349692360 49695184 0.000721524 −36.80171583 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 49940117 49941426 5.70E−05 −29.68770968Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 50359583 50360007 2.22E−11−36.41238882 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 50402058 504025630.006339783 21.59683236 Hyper-methylated NEPC|CRPC-Adeno DMRs chr350480513 50480616 0.001694183 −55.54561404 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 50502527 50502597 0.001694183 −34.05877193Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 50795465 51221599 2.36E−08−27.51373467 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 51298580 513787850.002174767 −25.00891898 Hypo-methylated NEPC|CRPC-Adeno DMRs chr351489993 51509734 0.000549237 −21.61428571 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 51818199 51853767 0.007136365 −30.72330827Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 51884494 51944246 0.000549237−22.36215626 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 52402672 524033332.17E−07 −30.96656347 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 5253780352537879 5.50E−05 −39.98304094 Hypo-methylated NEPC|CRPC-Adeno DMRs chr353837301 53837653 1.55E−06 −45.31413255 Hypo-methylated NEPC|CRPC-AdenoDMRs chr3 61280786 61280835 0.000549237 29.31353383 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 66002883 66002980 0.000832692 −44.35584795Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 68056641 68057167 0.00033766424.25637427 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 71194772 712136460.001249757 38.60052651 Hyper-methylated NEPC|CRPC-Adeno DMRs chr372149779 72149976 0.000549237 −25.11597973 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 72305843 72308226 0.000176134 −40.72369281Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 74420028 74601215 0.000561687−20.24012346 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 74819415 750022110.001847465 −20.22825922 Hypo-methylated NEPC|CRPC-Adeno DMRs chr375668646 75668686 0.000224358 35.78859127 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 75683144 75697750 0.008187764 −27.61354724Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 75707580 75707707 1.43E−0525.20830688 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 75707805 757078260.001694183 20.24126984 Hyper-methylated NEPC|CRPC-Adeno DMRs chr375721563 75721594 0.001249757 28.05324722 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 87042004 87091725 0.001549499 −26.87361111Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 87424528 87728434 2.36E−10−31.3923574 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 87891471 880360204.03E−08 −29.81320106 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 9402478894656908 2.08E−10 −28.72438824 Hypo-methylated NEPC|CRPC-Adeno DMRs chr394665363 95313928 1.73E−11 −25.90864732 Hypo-methylated NEPC|CRPC-AdenoDMRs chr3 107833652 107872310 0.003525992 21.93820663 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 111431503 111469563 0.000549237 −49.08404221Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 113417992 1134183390.000184724 26.3654321 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3115133824 115332585 0.000153872 21.5758302 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 119528807 119529068 3.68E−07 −23.09808493Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 123003270 1230035290.002859601 −24.85842105 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3123166795 123166905 1.09E−08 36.64989731 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 123420221 123420466 0.000549237 27.37769424Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 125677175 125677258 6.03E−06−28.87922379 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 126397531126397741 0.007136365 −38.14205182 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 126714171 126715234 0.000542154 20.40382775 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 126716223 126718487 0.004222625 −24.42193171Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 127056919 127057150 2.62E−1324.48829205 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 127318195127318252 1.70E−05 −31.73754386 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 128140328 128141587 6.06E−05 31.58228906 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 128209516 128211155 7.02E−16 23.13433595Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 128564943 1285650940.003525992 25.81143791 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3128653931 128658829 0.009458442 −23.43259569 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 128787249 128787525 0.000176134 22.60641161Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 129299973 1293001130.003113626 −23.35964912 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3131753881 131753954 2.46E−05 42.16437247 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 137501042 137626636 0.001694183 −22.18415831Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 138765942 138825790 8.71E−07−36.06678363 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 138904612139053137 7.90E−08 −28.08957955 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 139379620 139396853 8.52E−17 −21.95038986 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 140814064 140814119 0.001694183 −44.70272904Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 143130737 1432929910.000209051 26.59270335 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3146187388 146188416 8.97E−08 −20.11957467 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 146872122 146872206 0.001694183 −20.10057261Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 147126697 147129334 5.56E−2822.61330125 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 148040232148335993 3.46E−05 −23.96160533 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 150675538 150696776 0.004750844 −22.97752193 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 151158578 151379420 0.0001635  −25.03709511Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 151523968 1515254650.000484821 −33.37719089 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3152277188 152352045 4.43E−06 −23.09415461 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 152927587 153356991 6.83E−14 −22.6334674Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 153403846 153563964 1.56E−05−30.3546326 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 153641300153784041 0.000220189 −30.0825597 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 154085753 154087701 0.000101637 −35.56562703 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 154157310 154337500 7.30E−06 −28.766122Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 154375244 1544023950.001012154 −32.22529854 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3155463652 155463812 0.000100851 −20.62018912 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 156823183 156827612 0.001549499 −32.36907895Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 160822530 160823121 2.31E−19−22.30868407 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 163719850163722226 3.13E−05 20.42541845 Hyper-methylated NEPC|CRPC-Adeno DMRschr3 169529889 169542956 1.02E−07 −22.10761543 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 170143047 170143637 0.000101637 −34.83489279Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 170303534 1703037010.001345309 21.21021853 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3179754224 179755087 2.04E−27 20.14397085 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 180806076 180901040 0.004750844 −22.86944444Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 181443544 1814446660.004750844 26.24013158 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3181445726 181445848 0.001694183 −23.33333333 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 182832766 182849284 0.000581135 −31.90026714Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 184243296 184243766 6.36E−10−25.23778195 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 184387338184387555 0.005737741 23.92660245 Hyper-methylated NEPC|CRPC-Adeno DMRschr3 184390859 184391068 0.00222033  −22.61023392 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 184468640 184468809 0.002219003 −22.76349903Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 185967142 185974096 2.78E−05−32.21808754 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 186803480186822011 0.001694183 −22.74025341 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 187455621 187456337 8.94E−07 22.32549402 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 192232381 192233064 6.75E−17 24.99494642Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 192958797 192959334 6.14E−1826.90095889 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3 194004633194012571 0.00217795  −23.094957 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 195535764 195537532 1.49E−07 −23.34058058 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr3 195540912 195541268 0.003327791 −31.36421784Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 195943487 1959441550.005557404 20.61833812 Hyper-methylated NEPC|CRPC-Adeno DMRs chr3196756053 196756225 0.000488426 23.03403002 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr3 196763256 196763582 1.48E−06 −21.12447712Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 197183430 197183678 9.45E−11−20.69183007 Hypo-methylated NEPC|CRPC-Adeno DMRs chr3 197401863197401996 0.000549237 −30.25331466 Hypo-methylated NEPC|CRPC-Adeno DMRschr3 197478835 197478908 0.001694183 −26.56851852 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 107043 107915 2.73E−26 26.96540576Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 206385 207594 1.76E−1433.35279909 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 298777 2990472.76E−10 29.60379963 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 568636568670 0.000549237 23.60977444 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 568722 568943 1.52E−10 26.39615961 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 640366 640542 1.18E−06 20.53181818 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 645310 645516 0.001549499 −22.25473684Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 681086 681321 0.00015187433.80914407 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 692357 6924780.001694183 −42.88430799 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4956594 956985 1.09E−08 −43.20475648 Hypo-methylated NEPC|CRPC-Adeno DMRschr4 985827 987836 2.02E−07 39.15922807 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 1016193 1016726 2.25E−12 −34.95869106 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 1022723 1022833 0.000101637 −20.84780033Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 1187895 1189161 2.21E−15−31.63918454 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 1338704 13387660.003525992 40.58947368 Hyper-methylated NEPC|CRPC-Adeno DMRs chr41398537 1398599 0.001694183 27.86432749 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 1498090 1505299 0.001802623 −21.39334289 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 1558319 1562804 5.04E−06 −20.70367537Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 1624271 1625485 7.43E−14−25.61002803 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 1774883 17751241.70E−05 −37.59871345 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 18001451801295 2.71E−07 −27.30936937 Hypo-methylated NEPC|CRPC-Adeno DMRs chr41827195 1827262 0.001802623 −21.5443609 Hypo-methylated NEPC|CRPC-AdenoDMRs chr4 2072559 2074840 0.000564611 −22.87341029 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 2298384 2298660 9.74E−06 −35.45146199Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 2305552 2305706 0.000185897−28.37493075 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 2305758 23060522.68E−06 −34.7459964 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 24345392435008 0.006597219 23.87213085 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 2451848 2452312 0.000488426 −21.58349342 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 2765269 2765879 4.87E−05 30.70148586Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 2925380 2926347 3.21E−06−28.64409357 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 3241235 32418274.24E−06 −35.8 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 3309966 33120027.41E−07 −54.48064968 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 33662923366474 0.001694183 −38.41822612 Hypo-methylated NEPC|CRPC-Adeno DMRschr4 3474193 3475085 8.06E−06 −28.33222732 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 3514679 3514737 0.001694183 24.83879142Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 3681675 3681807 5.17E−06−30.86836789 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 3716949 37171400.000303685 −25.50873753 Hypo-methylated NEPC|CRPC-Adeno DMRs chr43733981 3734137 0.001694183 −34.38421053 Hypo-methylated NEPC|CRPC-AdenoDMRs chr4 3752682 3752983 2.14E−05 −26.1192147 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 3776475 3777021 0.000153872 −33.26239766Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 4358241 4361641 0.001694183−28.7162768 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 6010217 60132670.009458442 25.96772262 Hyper-methylated NEPC|CRPC-Adeno DMRs chr46130336 6130384 0.009274146 −45.78013158 Hypo-methylated NEPC|CRPC-AdenoDMRs chr4 6339082 6344362 0.001910709 −20.0326664 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 6480444 6480572 0.001802623 −34.07218045Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 6728813 6729056 2.68E−06−20.47771673 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 6748332 67484650.000549237 −24.35568333 Hypo-methylated NEPC|CRPC-Adeno DMRs chr46912457 6912580 0.001545937 20.05412606 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 7124395 7126572 0.002227988 −20.14088598 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 7137251 7149747 0.001798167 −21.35181579Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 7150037 7150269 0.007136365−28.80891936 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 7279290 72796710.001694183 −33.24603175 Hypo-methylated NEPC|CRPC-Adeno DMRs chr47324147 7326286 0.000224358 −40.91433007 Hypo-methylated NEPC|CRPC-AdenoDMRs chr4 7479768 7483229 0.000194166 −23.96654504 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 7647689 7648003 0.000102266 −22.97096909Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 7741447 7742184 4.06E−08−20.980728 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 7968382 79685970.000253274 −27.80275198 Hypo-methylated NEPC|CRPC-Adeno DMRs chr48012496 8012553 0.000176134 −38.73172515 Hypo-methylated NEPC|CRPC-AdenoDMRs chr4 8046683 8048885 0.000291618 −25.89386272 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 8052250 8055954 0.000112347 −22.22377451Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 8137397 8137658 5.17E−06−34.367615 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 8190304 81913969.83E−06 −34.8466893 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 82723028272921 0.003652661 −23.68561404 Hypo-methylated NEPC|CRPC-Adeno DMRschr4 8308030 8311070 4.78E−05 −24.47625081 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 8502797 8519884 1.46E−09 −22.1239748Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 8546717 8556387 9.53E−06−23.64667996 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 8562389 85768909.61E−06 −26.53628769 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 88599218859996 4.58E−05 25.42064777 Hyper-methylated NEPC|CRPC-Adeno DMRs chr48860131 8860181 0.000828392 27.84342105 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 8862448 8863406 6.12E−26 20.57156307 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 8865001 8867237 0.0001248  −21.6385888Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 8873115 8874580 1.28E−2834.66035175 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 8876016 88762161.89E−09 21.82916667 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 89658328966099 0.001594211 26.88586944 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 14864563 14864658 0.000667554 23.11719298 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 15779999 15780328 5.42E−10 20.96438845Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 15907622 15907745 3.76E−08−29.14906256 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 21950297 219505135.04E−12 27.10330817 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 2200422122261118 0.00047236  −25.07491056 Hypo-methylated NEPC|CRPC-Adeno DMRschr4 22601034 22605890 9.54E−05 −20.18913847 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 25972024 25972308 0.006785531 −29.5401133Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 31999120 32143213 0.004906972−21.40697095 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 35465234 354967810.003327791 −23.69766082 Hypo-methylated NEPC|CRPC-Adeno DMRs chr437245332 37247113 2.12E−32 27.71839273 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 37891793 37892014 8.67E−07 −28.78396954 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 44449486 44450642 2.59E−31 39.84740685Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 46391929 46392389 3.90E−1030.72768404 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 48995814 490282590.00064342  −25.52280702 Hypo-methylated NEPC|CRPC-Adeno DMRs chr452943055 52943231 1.37E−07 22.2200188 Hyper-methylated NEPC|CRPC-AdenoDMRs chr4 69264478 69265296 0.000549237 −22.9556391 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 73573436 73617031 0.005557404 −23.02609357Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 75860240 75860322 0.000488426−29.80107212 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 77342147 773426911.24E−09 −23.00629699 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4100573828 100574479 5.11E−12 −27.28129275 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 103131764 103158583 0.005737741 −23.25396825Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 109092629 1090927490.000263232 26.56473684 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4109692948 109709129 0.0001635  −27.47655502 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 111178753 111367020 3.47E−08 −31.98680845Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 111543324 1115435210.001345794 20.90681244 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4111544325 111544400 4.65E−07 20.64331984 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 111555162 111555247 0.000118331 24.78863826Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 113430635 113431994 1.28E−09−20.32926857 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 113442037113444633 0.000670739 20.5255289 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 119186690 119186881 1.00E−11 37.90779133 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 122080124 122299730 2.12E−07 −22.68246801Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 122685757 122686454 9.67E−1429.48130205 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 134071988134073990 3.79E−27 20.93377544 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 139726023 139726078 0.001694183 25.81993177 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 140707856 140760460 0.005737741 −34.00315546Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 143766812 143767085 5.97E−11−21.33005729 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 144833165144833504 7.16E−11 25.91972915 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 147559923 147559956 0.001694183 −21.32539683 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 147561282 147562108 0.000100877 21.86546956Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 147569270 1475692910.001694183 21.37329435 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4147901913 148151807 0.00025311  −23.67947345 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 148213356 148268629 1.70E−05 −29.28543172Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 153941239 1539413900.004750844 −30.23157895 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4154143655 154144921 4.12E−16 −27.29381106 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 154680909 154681339 9.88E−11 23.42486388Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 154709607 1547096850.000549237 25.83609023 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4154709813 154710192 1.10E−10 28.27913385 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 154711171 154711347 0.001694183 −25.4120614Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 154712129 154713601 3.29E−1225.36497873 Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 155411495155411720 1.31E−14 27.98769186 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 156135533 156253885 0.004750844 −37.45413534 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 158141449 158143729 5.05E−24 20.03226006Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 160393088 160595703 7.96E−06−25.7773823 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 160652638160790501 1.86E−06 −26.32935372 Hypo-methylated NEPC|CRPC-Adeno DMRschr4 160917553 161230823 4.74E−05 −20.76706679 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 164253010 164253056 0.000549237 26.1337146Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 165703722 165854644 1.14E−07−22.79351436 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 165952764165952870 2.91E−05 −21.80339932 Hypo-methylated NEPC|CRPC-Adeno DMRschr4 165953157 165976637 0.000711935 −24.31388889 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 166500186 166720741 0.000112177 −24.22509659Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 170785691 170893524 8.77E−06−26.8739956 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 174437845174437944 0.002927544 22.5251462 Hyper-methylated NEPC|CRPC-Adeno DMRschr4 174450465 174451873 6.56E−16 22.5629451 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr4 174459376 174459588 0.000667554 32.42068161Hyper-methylated NEPC|CRPC-Adeno DMRs chr4 175339069 1754330930.000263673 −26.26754386 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4178782781 178832448 0.001802623 −23.4431391 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 183081214 183120339 1.27E−06 −30.30664201Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 183241123 1833111330.00010588  −25.35918518 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4183402714 183493254 2.92E−09 −32.79803653 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 183529792 183698872 1.20E−14 −29.65124633Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 183801572 1838019490.001694183 −23.68157895 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4186545426 186545487 0.000176134 −30.88093933 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 187025976 187028029 6.02E−19 −21.34827446Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 187225016 1872468130.005899637 −25.28902649 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4187580851 187581221 0.000184724 −24.95337308 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 188377454 188377608 0.000549237 −34.25639098Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 188964162 1889643320.002976353 −27.25124717 Hypo-methylated NEPC|CRPC-Adeno DMRs chr4189084649 189100194 1.27E−05 −21.01399086 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr4 189155003 189167421 0.002569607 −24.64791701Hypo-methylated NEPC|CRPC-Adeno DMRs chr4 189220569 189224791 5.36E−06−26.43492934 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 491048 4914632.66E−08 −28.92773025 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 532829533068 0.005899637 −24.31432749 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 607867 607969 0.001694183 −28.22245614 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 628539 629117 0.006785531 −24.25783884Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 669261 669386 0.00119787430.94987843 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 961668 9619031.55E−06 −23.43138688 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 9932461004433 1.98E−10 −40.44307174 Hypo-methylated NEPC|CRPC-Adeno DMRs chr51125206 1130375 0.002094266 −25.08654971 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 1193728 1194028 2.64E−06 −23.43138402 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 1394522 1394673 0.006847068 −27.14201681Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1400370 1401940 0.001545937−23.71578947 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1444727 14447790.000224358 22.92894737 Hyper-methylated NEPC|CRPC-Adeno DMRs chr51513080 1513260 0.001694183 −25.01560847 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 1643928 1644137 0.001065261 23.71476608 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 1686216 1701618 9.09E−05 −27.965722Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1704542 1725347 4.71E−07−23.24799112 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1751468 17629530.000450645 −25.04540898 Hypo-methylated NEPC|CRPC-Adeno DMRs chr51777897 1787184 0.000220525 −20.11717605 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 1787937 1789080 0.003525992 −43.53194014 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 1835051 1836678 0.000642419 −25.0901864Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1837723 1840348 0.000579916−20.45676692 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1850715 18511200.002094266 −23.03810507 Hypo-methylated NEPC|CRPC-Adeno DMRs chr51858706 1869906 1.47E−09 −29.91434874 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 2213580 2261535 5.83E−10 −25.43094034 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 2301017 2334910 2.87E−05 −28.18859284Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 2671287 2697609 4.11E−07−33.12029584 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 3536326 35380470.000231593 −27.932665 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 35945143594587 0.00222033  22.14407895 Hyper-methylated NEPC|CRPC-Adeno DMRschr5 3595765 3596010 2.02E−06 21.64462719 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 3596307 3596795 1.16E−14 23.44162339Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 3600783 3603155 8.35E−1522.84933937 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 5231182 53178621.03E−06 −24.45755393 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 53371385421549 7.94E−07 −26.21022812 Hypo-methylated NEPC|CRPC-Adeno DMRs chr56181706 6191114 0.002859601 −24.1171345 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 6609478 6614935 0.000549237 26.78796992 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 7077307 7077546 0.00041315  −25.21176088Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 8430191 8789256 1.62E−1633.12498171 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 10860497 113138342.44E−17 −28.0495594 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 1139718811857366 3.40E−10 −33.659854 Hypo-methylated NEPC|CRPC-Adeno DMRs chr516867031 16867167 0.003525992 −46.08001949 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 19142240 19143195 0.000732983 21.70137275Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 22654559 22972651 0.00011018 −28.1783577 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 23688436 236885490.009458442 −27.97894737 Hypo-methylated NEPC|CRPC-Adeno DMRs chr529390802 29390973 5.50E−05 −25.14139051 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 31589171 31610599 0.001802623 −20.12206356 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 31692445 31693027 0.007136365 28.55391657Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 31693538 31727938 2.91E−05−21.46961097 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 32251322 322643350.006785531 20.54736842 Hyper-methylated NEPC|CRPC-Adeno DMRs chr532721605 33311293 2.10E−07 −33.78018252 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 33937050 33938305 9.51E−10 24.61330833 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 35091209 35134654 0.001076438 −38.62090322Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 35619506 35892413 7.81E−09−35.5425661 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 36727808 367378610.000324528 −26.73156981 Hypo-methylated NEPC|CRPC-Adeno DMRs chr537666116 37666267 5.50E−05 −27.19408707 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 37862565 37952562 0.000200729 −28.0684014 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 38113779 38190504 2.14E−06 −26.21596147Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 38211357 38244733 0.007832634−21.04698204 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 38290998 383551615.10E−05 −25.96060855 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 3913225639333984 5.29E−07 −25.60535782 Hypo-methylated NEPC|CRPC-Adeno DMRs chr539343335 39390614 5.75E−05 −36.85578947 Hypo-methylated NEPC|CRPC-AdenoDMRs chr5 39429528 39622086 2.41E−06 −34.54174325 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 39649723 40539431 8.04E−18 −28.16500715Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 42516504 42752667 5.50E−05−31.89449604 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 43000398 430007779.48E−10 −22.56860624 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 4569561845696419 7.45E−20 29.32638602 Hyper-methylated NEPC|CRPC-Adeno DMRs chr549897942 49903511 0.000549237 −20.92837302 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 50685513 50695269 4.32E−20 23.85970528Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 53948180 53988748 0.006785531−22.22867647 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 54179645 541801114.20E−09 27.60839089 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 5689733957058095 1.12E−05 −23.87566471 Hypo-methylated NEPC|CRPC-Adeno DMRs chr562324096 62850021 0.001026234 −21.78368514 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 67483406 67483572 1.50E−06 −32.34401604Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 72746667 72746714 0.00169418327.68421053 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 76022280 760286490.001552631 −22.64898325 Hypo-methylated NEPC|CRPC-Adeno DMRs chr576061717 76078695 0.001545937 −21.58327914 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 76249807 76250089 3.01E−08 21.51725325Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 76932335 76932495 8.24E−0522.06547128 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 77815597 778890250.001452666 −23.08098595 Hypo-methylated NEPC|CRPC-Adeno DMRs chr579469275 79485204 0.000324528 24.55337762 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 79865118 79865343 5.01E−05 −22.12807018Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 83679871 83680735 1.17E−1222.62946109 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 86765324 867958316.00E−07 −37.60657035 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 8688336787066719 0.006785531 −22.46150145 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 87968636 87971646 6.35E−13 26.16172775 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 87974174 87976063 0.000220189 21.77493192Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 89006887 89704529 2.98E−05−21.42766445 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 95767768 957678640.003525992 −24.34814815 Hypo-methylated NEPC|CRPC-Adeno DMRs chr596038303 96038858 3.02E−14 28.67572751 Hyper-methylated NEPC|CRPC-AdenoDMRs chr5 96915078 97074935 0.002094266 −24.71471544 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 113259183 113259266 0.001694183 −31.04210526Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 113498744 113658960 1.41E−05−30.62287889 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 113721736114031471 4.65E−07 −31.84509109 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 114054410 114265033 1.92E−06 −23.85403307 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 115297294 115298092 2.70E−07 23.95747703Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 115298702 115298783 5.50E−0521.64619883 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 119008929119162031 1.34E−07 −21.04597621 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 120154181 120245345 0.001549499 −22.87368421 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 122422309 122423615 4.23E−09 30.39827558Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 125784436 1258016240.000200845 −20.13070175 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5126626530 126626849 0.000424361 26.47919799 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 127929967 128268295 1.85E−05 −26.69549016Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 128920788 129000785 8.98E−08−40.22752932 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 129242259129813660 0.002215223 −23.6386056 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 129899475 130101707 0.000209051 −25.75539283 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 130281834 130331046 4.98E−06 −30.01544394Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 132167655 132173260 7.67E−0521.36149143 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 132707535132707620 0.001694183 −43.18323587 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 134477662 134515249 0.00217795  −32.9503096 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 134582848 134583164 0.00020815  −27.9623968Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 138281818 1382848320.005297267 −24.62317559 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5138441349 138441563 0.000176134 −72.83048783 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 140011903 140012735 3.67E−07 −25.94475993Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 140536613 140626811 1.72E−3123.92451239 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 140710358140718835 7.26E−05 21.82257932 Hyper-methylated NEPC|CRPC-Adeno DMRschr5 140731220 140746961 1.47E−15 25.84078042 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 141087185 141133473 6.07E−05 23.08007373Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 141263002 141263271 1.36E−1327.20863158 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 141566562141600717 0.006494419 24.1505214 Hyper-methylated NEPC|CRPC-Adeno DMRschr5 144867410 144867547 0.001694183 −23.73368665 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 145725544 145725821 1.57E−06 23.39155818Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 149570212 149572479 2.91E−05−30.75812191 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 149979489149980177 0.006890179 −25.38671679 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 150614450 150614558 0.003475856 24.35338346 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 153853305 153855316 3.45E−07 25.49400403Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 153858648 153862193 6.94E−2128.25829046 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 153896878153901173 0.000176134 20.55437204 Hyper-methylated NEPC|CRPC-Adeno DMRschr5 157098822 157098921 0.000100851 25.96363636 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 158335905 158342242 0.001694183 −34.98245614Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 159964850 1600829800.000921835 −21.92822967 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5160592487 160593463 2.78E−10 −34.87710834 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 161397997 161489472 0.002094266 −28.33618421Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 165965200 1659835470.003113626 −25.15536062 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5166211800 166211938 1.77E−05 −32.10517962 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 166216555 166358616 4.65E−10 −21.25623053Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 168031856 1680709220.008985252 −20.85302144 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5169780009 169814440 0.000114388 −21.95998254 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 169905415 169916149 0.000277187 −30.32534909Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 170068701 170094209 9.28E−06−23.78628472 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 170171206170171278 2.91E−05 20.41866029 Hyper-methylated NEPC|CRPC-Adeno DMRschr5 172281596 172285250 0.008985252 36.9627193 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 172640852 172655078 0.00324027  −26.57418516Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 172717583 1727189730.001156603 −39.31137218 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5172751331 172751409 0.000549237 −35.98646617 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 172924855 172924910 0.003525992 23.18267544Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 172982435 172982612 1.77E−05−21.40207337 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 173060626173060693 0.001694183 −50.75175439 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 173416735 173416924 0.000324528 −32.68230295 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 173937899 173954821 0.007379618 −27.30172306Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 175222595 1752226640.001694183 20.47368421 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5175299618 175305219 7.59E−05 −20.60035425 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 175488179 175488850 7.42E−07 31.99841923Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 176023532 176024630 1.66E−0932.75785602 Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 176225635176226125 1.37E−07 −29.15918964 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 176799200 176803611 0.001549499 24.3224681 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr5 177513281 177513608 3.60E−08 −26.53032288Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 177694310 177729158 1.16E−17−22.86636965 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 177804400177808731 3.56E−06 −33.93883514 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 177831014 177849724 1.92E−09 −22.83100111 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 177852613 177852714 0.000892405 −22.98275272Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 177936432 177964582 4.91E−11−22.72903964 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 178368052178368441 9.56E−09 27.05484081 Hyper-methylated NEPC|CRPC-Adeno DMRschr5 178415954 178416070 0.007136365 −34.0329753 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 178421442 178422158 2.80E−34 37.76057537Hyper-methylated NEPC|CRPC-Adeno DMRs chr5 179051472 179051611 3.05E−05−25.67095517 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 179401758179401883 0.000100851 −59.28431685 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 179546299 179553332 0.002976353 −22.9599832 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 179555790 179563506 0.000176134 −23.24616634Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 179581131 179597814 1.09E−12−43.12640294 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 179604314179604469 0.000104758 −20.69416137 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 179621364 179621503 0.001802623 −20.7593985 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 179745870 179745934 0.001156603 −21.53157895Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 179771685 1797744840.008985252 −21.90175439 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5179813185 179826025 1.76E−05 −22.29042426 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 179839133 179840031 0.000176134 −26.82236842Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 180046943 1800473070.000477706 −22.37200378 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5180051729 180056041 0.005737741 −20.84230019 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr5 180487437 180495651 0.001694183 −35.69327485Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 180541324 180558751 8.72E−06−20.30473007 Hypo-methylated NEPC|CRPC-Adeno DMRs chr5 180579854180581312 1.70E−05 −21.35021721 Hypo-methylated NEPC|CRPC-Adeno DMRschr5 180601471 180602019 0.006785531 21.79078947 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 380009 387097 2.91E−05 −39.2166135Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 920943 1026676 1.39E−08−21.3173171 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 1072544 10808342.04E−06 −23.11078533 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 10916341169971 4.28E−08 −22.86548112 Hypo-methylated NEPC|CRPC-Adeno DMRs chr61171332 1204780 0.002692265 −23.47569337 Hypo-methylated NEPC|CRPC-AdenoDMRs chr6 1218137 1311386 3.57E−06 −23.75880713 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 1325258 1368287 1.15E−05 −30.48767753Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 3247958 3248099 0.001694183−20.45175439 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 3312949 33132530.001694183 −42.26111111 Hypo-methylated NEPC|CRPC-Adeno DMRs chr64609129 4609215 0.001694183 −51.94346979 Hypo-methylated NEPC|CRPC-AdenoDMRs chr6 6534755 6534840 0.000324528 −21.79736842 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 6901786 6921548 0.001694183 −29.42330827Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 7051203 7051498 5.36E−06−20.11754386 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 7142066 71512101.65E−05 −32.35656884 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 79116037916324 0.003327791 −36.64860681 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 15034147 15034388 0.003327791 −34.24130224 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 16231908 16234723 0.000549237 30.56424394Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 16597423 16663495 7.00E−05−26.31060606 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 26225433 262336697.16E−08 23.06214273 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 2723515427244420 0.001694183 −27.96274018 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 27507081 27507125 0.001694183 22.48333333 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 28469380 28469639 0.005737741 −20.65740741Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 28925778 28925944 0.001694183−28.05874408 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 29004357 290979600.002201952 −34.40877193 Hypo-methylated NEPC|CRPC-Adeno DMRs chr630139933 30139979 1.70E−05 22.23368421 Hyper-methylated NEPC|CRPC-AdenoDMRs chr6 31079577 31088463 0.002593231 −21.8442617 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 31127321 31127440 0.007136365 −27.53458647Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 31153818 31153913 0.00169418334.23606238 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 31516024 315160940.001694183 −37.28596491 Hypo-methylated NEPC|CRPC-Adeno DMRs chr631630341 31631937 0.004750844 −23.58442982 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 31799374 31800092 0.005737741 26.72913083Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 31869003 31869196 4.42E−06−29.89239035 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 32010328 320149580.000190593 −29.32598899 Hypo-methylated NEPC|CRPC-Adeno DMRs chr632017304 32055214 5.09E−07 −20.81007653 Hypo-methylated NEPC|CRPC-AdenoDMRs chr6 32064904 32066461 6.10E−05 −23.97378718 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 32222668 32334465 4.20E−09 −34.72389005Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 32441758 32452229 0.000400293−37.43005757 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 33129850 331370580.000414837 −25.05707741 Hypo-methylated NEPC|CRPC-Adeno DMRs chr633694845 33695935 0.009822962 −31.77889421 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 33798997 33806285 0.001883547 29.24174641Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 33825371 33826398 0.00475084423.00517962 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 34097690 341057860.003327791 22.2208973 Hyper-methylated NEPC|CRPC-Adeno DMRs chr635479466 35480074 0.001330041 20.53398415 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 35732621 35732826 8.87E−06 −27.25141326Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 35944410 35944479 0.000549237−22.55545113 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 36297769 362979290.004750844 −22.06130461 Hypo-methylated NEPC|CRPC-Adeno DMRs chr636308454 36308550 0.003525992 23.19824561 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 36808647 36808895 2.23E−05 33.42605994Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 36966633 36966850 0.001694183−38.27293888 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 37027177 370273910.007271222 −20.91616099 Hypo-methylated NEPC|CRPC-Adeno DMRs chr637056029 37070024 0.009458442 −27.40789474 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 37099083 37099308 0.007136365 −26.66461743Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 37616620 37618010 4.47E−1125.62558993 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 37673065 376731640.000549237 −21.87928363 Hypo-methylated NEPC|CRPC-Adeno DMRs chr638683142 38683226 0.000200814 28.21157895 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 39152904 39156039 0.002976353 −27.9625731Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 39281155 39281986 4.39E−26−28.4892065 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 40556525 405674080.000193859 32.46491228 Hyper-methylated NEPC|CRPC-Adeno DMRs chr641515524 41520612 6.22E−07 −22.56560987 Hypo-methylated NEPC|CRPC-AdenoDMRs chr6 41645384 41645574 4.03E−08 −22.91719298 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 41691450 41701472 7.22E−05 −35.28975318Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 42211020 42222590 1.46E−0520.48666667 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 43252789 432531542.58E−12 36.14350552 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 4369192743701954 0.009458442 22.59639376 Hyper-methylated NEPC|CRPC-Adeno DMRschr6 43859217 43871833 0.001249757 −41.6247076 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 49518155 49519263 1.68E−16 −33.59982026Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 51880478 51918106 0.000324528−23.72643189 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 52148092 521481470.003113626 −34.22270955 Hypo-methylated NEPC|CRPC-Adeno DMRs chr664150762 64152040 0.000171929 −40.23906883 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 67748043 68598961 3.10E−15 −25.69795914Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 68824520 69073198 4.95E−05−31.59374966 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 72142128 722952605.17E−06 −34.35036075 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 7229831072298363 0.000168572 22.91835512 Hyper-methylated NEPC|CRPC-Adeno DMRschr6 73195959 73196049 0.001694183 −26.99074074 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 73446873 73686160 0.007136365 −29.79794585Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 74058053 74058290 0.000581135−20.50277778 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 74058740 740588150.000549237 21.63492063 Hyper-methylated NEPC|CRPC-Adeno DMRs chr674063014 74063837 0.000549237 −25.36293733 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 74079707 74095500 3.15E−05 −21.10204365Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 75799863 75799927 0.001694183−34.3537037 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 76022149 760297390.002201952 −21.98854167 Hypo-methylated NEPC|CRPC-Adeno DMRs chr678172277 78172873 2.71E−07 27.93775017 Hyper-methylated NEPC|CRPC-AdenoDMRs chr6 78372148 79244679 7.90E−06 −28.25903182 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 85483168 85484776 6.94E−28 28.62015171Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 90597327 90597525 1.06E−0820.1827957 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 94183722 943472770.000184724 21.32184874 Hyper-methylated NEPC|CRPC-Adeno DMRs chr696463182 96464064 4.24E−06 26.82815904 Hyper-methylated NEPC|CRPC-AdenoDMRs chr6 97440107 97440399 0.005737741 −36.85833333 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 97763759 98183523 0.001179842 −29.05151679Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 99290467 99291654 3.19E−1025.49718992 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 100050801100051345 2.35E−08 25.43145833 Hyper-methylated NEPC|CRPC-Adeno DMRschr6 100051516 100051798 1.52E−13 26.67049062 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 100053497 100053559 0.005737741 20.41486928Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 100441301 100441849 2.20E−1226.41419011 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 106442088106442130 5.50E−05 43.72367725 Hyper-methylated NEPC|CRPC-Adeno DMRschr6 108685423 108685477 0.001694183 −46.02698413 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 110720729 110721547 6.50E−07 30.20072239Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 117003416 1170034470.001430236 −33.85073529 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6117336184 117566170 0.000348917 −24.95925756 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 117650809 117774415 3.72E−05 −27.81867052Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 118071921 1181427370.000332311 −32.58397034 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6121192520 121292329 0.0077394  −22.9501462 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 122051071 122601919 6.76E−10 −31.22322451Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 125743175 1257672790.003113626 27.92060185 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6130135971 130319227 7.27E−07 −25.94394399 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 131076017 131091928 0.000176134 −23.28289474Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 131205293 131343090 2.48E−05−20.65603715 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 131615473131693099 2.71E−06 −22.20950501 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 132982727 133075066 0.003890964 −29.79025413 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 133561993 133563178 2.72E−20 34.25815513Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 134210997 1342111870.000328065 26.28901041 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6134213989 134217387 1.13E−05 28.18877971 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 134587469 134589635 0.008985252 −30.30441845Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 137662985 1376630690.001694183 −31.84912281 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6139003913 139004094 6.31E−05 −30.31959412 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 146550415 146745382 0.001545937 −24.0022742Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 149196103 1492076980.001694183 −49.44546261 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6149771897 149772344 1.04E−21 −26.17262824 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 149868167 149868236 0.000176134 −34.15972222Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 150161647 1501737190.003113626 −23.85284392 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6150226728 150231840 0.000549237 −20.91428571 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 151560872 151560928 0.001694183 23.8462963Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 155316153 1553163170.005972124 20.64532164 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6155577670 155577944 0.006785531 25.75248968 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 156919689 156919819 0.000549237 −26.87518797Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 157301740 1573018840.000549237 −27.48681999 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6157549697 157550558 0.000381376 −44.41951754 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 157638537 157695368 0.000614774 −35.25709208Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 158142482 1581434430.001694183 −21.9917842 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6158402097 158402130 0.001694183 42.13095238 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 159052282 159052968 0.000176134 35.46460376Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 159086455 159086574 5.50E−05−27.42098765 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 159178146159178308 0.000549237 −26.66904762 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 159179591 159180045 5.75E−05 −48.55696895 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 160647285 160768460 1.98E−16 −31.00488046Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 160770301 160908523 1.24E−10−26.58055134 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 160977157161056077 9.09E−05 −27.28460039 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 161106413 161188054 5.17E−06 −28.52580409 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 161188085 161188130 5.50E−05 38.73014133Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 161188265 161188350 1.02E−1325.70012531 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 162192054163130689 2.69E−45 −44.66560673 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 163185201 163558674 1.07E−16 −38.89754784 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 163744319 163749730 3.32E−05 −23.84523724Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 163786097 1638090700.001287702 −25.28347903 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6164051754 164051943 1.20E−06 20.89901063 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 164083974 164215623 1.12E−06 −26.32551847Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 166233001 166233231 1.22E−0539.48162072 Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 166267976166268220 1.89E−05 24.36348684 Hyper-methylated NEPC|CRPC-Adeno DMRschr6 166402580 166402611 0.000549237 −20.02255639 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 167263366 167263443 0.003525992 −26.17592593Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 167317683 1673178390.001694183 −37.67755991 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6167662768 167663357 0.001694183 −27.73148148 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 168461811 168463153 0.001600753 −36.86793592Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 168490497 168490753 4.65E−07−42.52564103 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 168532323168534097 3.03E−06 38.88784924 Hyper-methylated NEPC|CRPC-Adeno DMRschr6 168595964 168599827 0.001694183 −33.59880174 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 168678236 168678443 0.003113626 −24.14444444Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 168774238 168777827 9.94E−05−30.09728175 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 168927073168927139 0.001694183 −39.03518519 Hypo-methylated NEPC|CRPC-Adeno DMRschr6 168983447 168983516 0.000176134 −20.88888889 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 169017534 169020490 0.001694183 20.54945534Hyper-methylated NEPC|CRPC-Adeno DMRs chr6 169267548 1692677760.000926684 −20.20575163 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6169271008 169271390 0.000488426 −34.68547009 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr6 170224164 170224458 0.001694183 −34.65947712Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 170396258 1703963710.000549237 −44.08888889 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6170418159 170418327 4.65E−07 20.58706098 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr6 170449348 170449421 0.001694183 −46.28333333Hypo-methylated NEPC|CRPC-Adeno DMRs chr6 170468244 1704687630.00533697  −28.34436508 Hypo-methylated NEPC|CRPC-Adeno DMRs chr6170577679 170578638 0.000220189 −43.35607688 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 98021 117929 4.65E−07 −28.51790373Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 139180 139734 1.98E−05−21.85387989 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 162710 1628911.70E−05 −27.49614035 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 168126173660 1.10E−10 −20.44578345 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7186539 186625 0.003525992 −20.4508215 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 388177 388516 0.000148603 −22.96399068 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 461264 462764 1.70E−09 −28.04467959Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 502171 505484 1.25E−22−20.6690523 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 511489 5115701.70E−05 −22.72350877 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 519881525711 1.98E−05 −30.04869867 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7531628 532623 1.63E−05 −27.01310141 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 569903 570042 3.46E−09 −33.47004917 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 573034 576711 3.68E−08 −26.15599437 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 731360 733947 4.34E−06 −21.49363794Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 943496 943677 5.17E−06−26.22501899 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 975316 9754095.17E−06 −28.82902399 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 10369151037386 1.97E−05 −21.90503326 Hypo-methylated NEPC|CRPC-Adeno DMRs chr71116099 1116660 4.55E−08 26.47100765 Hyper-methylated NEPC|CRPC-AdenoDMRs chr7 1140343 1141234 0.002094266 −20.203771 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 1163153 1170455 1.01E−07 20.35215718Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 1297674 1300321 3.26E−07−22.72610939 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 1308374 13095193.39E−07 −28.25817853 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 13518241362126 5.19E−09 −23.90198515 Hypo-methylated NEPC|CRPC-Adeno DMRs chr71403804 1408569 0.000535455 −20.2246171 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 1409096 1409194 0.000581135 26.57816155 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 1447698 1447784 5.50E−05 −57.72644574Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 1486267 1486774 5.50E−05−35.45552307 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 1501203 15013062.58E−07 30.06159411 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 15729251574017 0.000112114 21.47932174 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 1625289 1627198 2.12E−12 −29.82460375 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 1638032 1639465 0.000324528 −20.00967492Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 1764914 1765159 5.50E−05−34.2920078 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 1786426 17866331.43E−09 −24.62849253 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 17989781799229 0.000151874 −31.57120196 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 1799972 1801577 0.000184724 −20.84769563 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 1972363 1973580 1.22E−05 −37.9066237Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 1988131 1988157 0.00747873429.64692982 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 2006578 20075074.03E−08 −50.03189084 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 20302252035752 3.70E−06 −21.53736424 Hypo-methylated NEPC|CRPC-Adeno DMRs chr72091247 2092597 3.81E−05 −35.92921831 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 2147551 2149019 8.71E−07 −23.28644708 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 2161050 2161107 0.000953892 −31.75082237Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 2183803 2184317 0.002976353−30.9028655 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 2544926 25451651.70E−05 30.98345029 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 27050462706334 8.77E−06 −27.42248804 Hypo-methylated NEPC|CRPC-Adeno DMRs chr72802248 2803117 4.74E−05 24.76065831 Hyper-methylated NEPC|CRPC-AdenoDMRs chr7 2953704 2953931 4.66E−05 −32.14649123 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 4031683 4047370 0.005574264 −23.16204147Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 4238898 4238967 0.00169418327.15126706 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 4831773 48319651.45E−08 35.25098688 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 48964904896642 0.001694183 −43.76929825 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 4901427 4901504 6.03E−06 26.68003063 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 5122981 5123129 8.34E−06 −21.24732665Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 5269948 5277035 0.00448401827.6063606 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 5571994 55722810.000176134 58.83446315 Hyper-methylated NEPC|CRPC-Adeno DMRs chr76653117 6655380 1.09E−08 −20.46297397 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 6894841 6910747 3.72E−05 −22.36660819 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 14942275 14942568 0.000100851 −22.76273259Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 16627263 16627563 5.17E−06−37.35151515 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 21985032 219858174.29E−23 −20.50324465 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 2247369122485269 0.001065261 −33.33907044 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 23513686 23514114 7.64E−11 29.63961782 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 24746385 24775234 6.23E−07 −24.75803664Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 26439818 26440049 1.70E−05−38.2158111 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 26667541 266678271.43E−05 −47.45877976 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 2713861527138758 0.000176134 −22.11076389 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 29370958 29390448 0.000667554 −29.61643963 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 29847139 29847207 1.55E−06 26.36096491Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 30509913 30510071 0.001694183−55.98412698 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 32109943 321109092.03E−14 21.86596629 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 3233796532338105 7.06E−06 27.35464181 Hyper-methylated NEPC|CRPC-Adeno DMRs chr733774146 33794990 0.001694183 −36.79699074 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 35293088 35294024 7.26E−15 21.08101678Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 35295107 35295185 0.00169418335.84756335 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 35297355 352981442.04E−10 24.12089977 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 3632067036320934 5.50E−05 −37.13281734 Hypo-methylated NEPC|CRPC-Adeno DMRs chr737331946 37385316 0.000716333 −21.19096816 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 37430881 37484208 4.58E−05 −36.78493027Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 39015634 39015684 0.00051503935.36695906 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 39926086 399645620.001274051 −30.42906973 Hypo-methylated NEPC|CRPC-Adeno DMRs chr740771513 40949002 1.42E−05 −24.80588235 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 41086076 41132732 5.17E−06 −42.73618695 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 42426194 42508085 1.99E−05 −24.13349489Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 42561891 42903008 2.06E−06−30.53066362 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 44080363 440805561.22E−05 −24.76478697 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 4412693144139802 0.004705671 −20.53388717 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 44184906 44186013 1.42E−06 28.87002755 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 44806979 44807422 0.000398142 −32.71807549Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 45188077 45188125 0.009458442−21.66140351 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 45756556 457614260.000549237 −32.43986156 Hypo-methylated NEPC|CRPC-Adeno DMRs chr745980036 46002378 0.006890179 20.33518519 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 46643054 46721722 0.002927544 29.52222222Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 47571357 47576935 2.54E−12−21.5275848 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 47783603 477836450.000832692 −25.76339286 Hypo-methylated NEPC|CRPC-Adeno DMRs chr747878999 47879110 0.000224262 −23.43659539 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 48178734 48241612 0.000341319 −27.77574658Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 49813013 49813981 5.85E−3324.51054198 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 50343250 503444531.24E−42 31.836395 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 5053874050541014 0.001694183 −35.38267544 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 50628625 50645521 0.001076438 −39.43436797 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 51210128 51248111 0.006847068 41.94803676Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 55507332 55507385 0.000176134−48.26915205 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 56242565 562428731.48E−07 29.56511716 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 5624296456243315 0.000209019 22.70106386 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 56515745 56515773 0.002976353 21.16766917 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 62514623 62514749 0.00013534  −24.38822612Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 63033542 63080718 0.000549237−21.75166372 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 63392167 634236541.46E−05 −27.3291205 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 6377521963903300 0.000522292 −23.27074167 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 64035306 64035529 3.73E−07 27.91159701 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 65879286 65894441 0.000926684 −33.99538012Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 67016138 67016209 0.000549237−41.44897959 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 67935792 679361000.001694183 −38.15175439 Hypo-methylated NEPC|CRPC-Adeno DMRs chr768442589 68460614 0.009285355 −31.69861111 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 70194169 70195030 0.000209051 −38.52631579Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 70543193 70571576 0.000109727−24.51994288 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 70598187 710406693.44E−23 −28.85128178 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 7106218371190948 3.79E−10 −29.87299605 Hypo-methylated NEPC|CRPC-Adeno DMRs chr771597750 71788886 1.15E−06 −22.92652133 Hypo-methylated NEPC|CRPC-AdenoDMRs chr7 71897417 71910527 7.00E−05 −36.82478031 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 73120427 73121745 0.005972702 −23.51048949Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 73130447 73130663 0.001694183−24.36789474 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 73292628 732938390.000291618 −31.06161616 Hypo-methylated NEPC|CRPC-Adeno DMRs chr773418548 73425014 0.00013534  −21.38034531 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 73444203 73448630 1.53E−09 −34.02355315Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 73877077 73877186 0.000549237−38.23776107 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 73928945 739291375.50E−05 −30.19239766 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 7531753775318296 1.83E−11 −46.11286929 Hypo-methylated NEPC|CRPC-Adeno DMRs chr775428466 75430067 0.001549499 −31.85328947 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 75889320 75896730 8.30E−08 36.39937221Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 77759060 77781012 0.002094266−25.62241715 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 80882862 809727800.000291618 −21.78708134 Hypo-methylated NEPC|CRPC-Adeno DMRs chr788055452 88361379 0.000100851 −23.3035807 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 89402663 89699986 0.000412306 −33.21182586Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 92224032 92238214 0.009167638−25.32917875 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 92556126 925563580.001694183 −29.33085655 Hypo-methylated NEPC|CRPC-Adeno DMRs chr793027070 93179659 0.000711935 −39.84444444 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 93215075 93412547 0.000247501 −23.22734832Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 93730217 93808002 0.000586307−21.47168435 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 96679152 966939100.00203966  20.39064327 Hyper-methylated NEPC|CRPC-Adeno DMRs chr797835013 97835047 0.000549237 −30.93055556 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 100074961 100075551 2.34E−07 31.55237793Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 100179198 100179430 5.50E−0522.38992702 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 100202591100203556 5.55E−09 −22.03045273 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 100243689 100244361 1.77E−05 25.94620587 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 100417332 100417781 0.000549237 −20.95118153Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 100420198 100420392 1.17E−08−28.21832707 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 100898266100925400 7.04E−08 −30.81060825 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 101047233 101079065 0.001694183 −24.88718926 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 101139439 101144324 9.81E−05 −22.89097744Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 101414527 1014251680.004583371 −24.94377231 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7101621974 101622208 5.17E−06 −54.88245614 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 101665615 101665823 0.000176134 24.99539474Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 101910353 1019112420.001012154 −22.14854995 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7101936417 101936520 2.46E−05 24.73095777 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 105278903 105284007 0.001931256 −35.47421428Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 112725862 1127259210.001694183 −22.27105263 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7113727429 113727696 5.76E−07 24.05758217 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 113778706 114075862 1.47E−07 −30.30602738Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 114344049 1145550110.000496559 −31.121275 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7114598663 114732973 0.001549499 −30.72328216 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 115992732 116099339 6.27E−05 −45.54482486Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 116173667 1162671290.004583371 −26.34456797 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7121950271 121951056 2.47E−13 27.29424703 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 121955826 121957299 6.21E−17 34.03237506Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 127992373 128001120 1.30E−05−20.45230586 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 128550114128550429 1.22E−05 −22.19552549 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 128843277 128849313 4.27E−05 −26.79529825 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 129142639 129142818 2.92E−07 −21.86956014Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 129412806 1294129480.000549237 −24.23127611 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7129781317 129781690 3.68E−07 −24.34286432 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 129882516 129913332 1.21E−07 −32.37775757Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 136952873 137139501 8.20E−11−43.46206543 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 137197633137254332 0.000286322 −33.9960858 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 137311605 137525101 0.001345309 −30.27186895 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 137938182 138042037 0.00022941  −20.49874223Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 138522694 1385228030.001694183 −34.89473684 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7138655625 138661116 0.00485991  −21.486132 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 139298972 139299083 0.003113626 −30.5287852Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 142370686 1424813530.009285355 −21.80197368 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7142708360 142906541 4.87E−08 −31.26127606 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 143612178 143726580 5.01E−05 −24.37532925Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 144098227 1440983040.001694183 −31.41666667 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7144098374 144098634 0.004750844 −32.26220313 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 145058020 145058080 0.000246327 21.84517544Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 147960685 1479790780.003525992 25.82192982 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7148984433 148984720 0.00222033  20.85131579 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 149095537 149095801 0.001036804 −21.1622807Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 149471151 1494715560.000359641 −22.15748194 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7149524893 149525284 4.65E−07 −39.64003599 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 150079771 150081431 5.99E−06 −39.78262322Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 150621610 150621785 1.70E−0529.44458204 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 150644519150646261 1.42E−05 25.27178943 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 150662422 150662622 5.50E−05 −23.34405458 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 150667475 150671111 1.30E−06 −43.13443251Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 150675719 150676606 5.93E−07−20.48260383 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 150758411150760530 1.43E−05 34.85106115 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 150808939 150813925 8.18E−54 44.44418402 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 150893625 150900164 3.37E−05 −25.05822328Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 151092893 151093764 6.06E−10−22.94295504 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 151106286151106600 2.74E−09 −20.15992325 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 151393319 151394486 4.14E−08 −23.24630848 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 151429904 151433341 0.00011018  −34.74701754Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 152264791 1522649760.000549237 −25.62052632 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7152312238 152312414 0.001694183 −32.59210526 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 152622035 152623255 1.86E−28 25.71285637Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 153446785 153549327 5.50E−05−28.3682223 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 153583498153585619 6.56E−12 20.91698318 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 153748243 153749230 1.27E−05 31.65437859 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 153749311 153750276 6.59E−08 24.22265676Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 154001966 1540020600.000477706 22.34518519 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7154679155 154684455 1.94E−06 −22.44733109 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 154700060 154701586 0.005403657 −23.3014295Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 154961046 1549612530.001694183 −26.43859649 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7155165258 155168194 2.90E−27 24.26971502 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 155175138 155175350 0.002094266 23.82149123Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 155249625 155250533 2.81E−3420.24216956 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 155290337155302510 5.20E−06 20.89056261 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 155588470 155588837 0.001545937 −26.29805068 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 155638043 155663408 2.24E−06 −22.9206979Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 155714959 155747399 3.86E−09−23.07660444 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 155794863155832993 1.55E−10 −22.35542129 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 155833027 155836135 9.75E−08 −28.87053472 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 155836603 155867869 2.57E−11 −23.74940534Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 155868074 155919738 7.69E−20−25.40228613 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 155920431155922570 0.002976353 −25.76846528 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 155935971 155939248 0.000601653 −23.24230306 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 155982087 156029669 1.42E−13 −28.43968047Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 157348105 157350761 4.24E−0625.56256498 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 157403114157403257 0.004750844 22.56158626 Hyper-methylated NEPC|CRPC-Adeno DMRschr7 157423165 157423277 0.000549237 53.27493734 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr7 157454381 157455220 7.40E−05 29.11805068Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 157623228 157623283 1.70E−05−50.66327485 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 157690139157690236 5.50E−05 −34.76632554 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 157808922 157809023 0.000549237 −24.04135338 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 157818540 157818816 9.59E−05 −26.57935538Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 158207219 158207489 1.70E−05−33.48434211 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 158240210158240447 1.55E−06 −36.61773879 Hypo-methylated NEPC|CRPC-Adeno DMRschr7 158749927 158751134 3.60E−08 −23.18690574 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr7 158765163 158766524 8.65E−16 31.75989633Hyper-methylated NEPC|CRPC-Adeno DMRs chr7 158823239 158824137 3.75E−05−23.994282 Hypo-methylated NEPC|CRPC-Adeno DMRs chr7 158828603 1588286450.001694183 30.85602241 Hyper-methylated NEPC|CRPC-Adeno DMRs chr7158933047 158935637 0.004222625 20.15096716 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 548319 554437 0.009458442 −35.44691488Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 563734 576584 0.000549237−40.41298186 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 687072 6874343.40E−08 23.17620574 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 688020688038 0.000176134 25.75520833 Hyper-methylated NEPC|CRPC-Adeno DMRschr8 688754 689448 2.90E−13 −22.82425701 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 933960 936280 0.000549237 −24.40636255 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 950333 962617 0.000342136 −27.82898801Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1019486 1041203 0.003095591−25.56203704 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1054052 11053552.46E−12 −26.32933308 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 11281471137662 8.33E−06 −26.51896592 Hypo-methylated NEPC|CRPC-Adeno DMRs chr81143735 1154350 0.000181909 −28.4736728 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 1205069 1284153 7.88E−10 −23.19659827 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 1287319 1307512 6.31E−05 −28.80687831Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1312025 1315290 5.84E−05−23.65079365 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1362644 13627840.004750844 −26.07539683 Hypo-methylated NEPC|CRPC-Adeno DMRs chr81372805 1390829 4.74E−05 −26.26034997 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 1414086 1414209 0.001012154 −30.51247166 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 1444068 1449174 1.70E−05 −28.34107143Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1474621 1496348 0.000220189−29.76194367 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1497354 14974920.000124569 −20.29679233 Hypo-methylated NEPC|CRPC-Adeno DMRs chr81502748 1581080 2.42E−09 −25.3213242 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 1585227 1611579 1.30E−09 −25.05703655 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 1615531 1633331 0.00324027  −22.63756614Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1914991 1915048 0.003525992−49.48412698 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1994504 19945860.001694183 −31.07671958 Hypo-methylated NEPC|CRPC-Adeno DMRs chr84664909 4773245 1.82E−05 −31.50027963 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 8699509 8699666 0.000176134 23.525 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 8702914 8703087 0.000549237 −50.08253968Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 9755120 9756237 0.00015441122.25699446 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 10260705 102626294.74E−05 −37.12539683 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1082321510823356 0.000176134 −50.19305556 Hypo-methylated NEPC|CRPC-Adeno DMRschr8 10897150 10906939 1.13E−06 −28.26510076 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 10950065 10950227 0.000176134 39.10277778Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 11318849 11319758 0.001802623−32.13730159 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 11444763 114570981.24E−05 −24.16021424 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 1155890811559680 5.17E−06 −28.58585859 Hypo-methylated NEPC|CRPC-Adeno DMRs chr811565860 11566334 1.51E−13 28.37685849 Hyper-methylated NEPC|CRPC-AdenoDMRs chr8 11566725 11566774 0.004750844 20.8968254 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 11571961 11583647 0.003327791 −24.87320261Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 11597630 11597787 0.000549237−33.01071429 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 11764122 117936050.000377187 −22.31187771 Hypo-methylated NEPC|CRPC-Adeno DMRs chr812990473 12991207 3.18E−05 21.23221748 Hyper-methylated NEPC|CRPC-AdenoDMRs chr8 13001419 13099347 6.14E−12 −43.75187325 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 13424251 13424290 0.003113626 26.33333333Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 15094264 15094372 0.00269226520.30185185 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 20170522 201705930.001694183 −37.83194444 Hypo-methylated NEPC|CRPC-Adeno DMRs chr821503796 21503979 0.000953892 −35.78457925 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 21647244 21647747 2.53E−14 24.90639297Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 21974245 21974541 6.91E−08−20.11501736 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 22004991 220052160.001202962 −21.21948335 Hypo-methylated NEPC|CRPC-Adeno DMRs chr822411622 22411875 0.005574264 −23.02929717 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 22595457 22595520 0.000549237 −27.67460317Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 22872097 22877339 0.00067511 −21.37640523 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 26558310 267215520.000975454 −33.78126653 Hypo-methylated NEPC|CRPC-Adeno DMRs chr826721749 26721984 1.13E−06 −22.59403935 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 26723523 26723602 2.46E−05 23.41193529 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 26724441 26724503 7.37E−05 21.10555556Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 28111255 28143729 0.000224358−23.8884127 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 28205271 282230520.000189694 26.08636204 Hyper-methylated NEPC|CRPC-Adeno DMRs chr829870043 29870110 0.001694183 −48.66666667 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 33371946 33372001 4.92E−05 −30.20517429Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 37655471 37655639 5.01E−0524.75416667 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 37755408 377554700.001012154 −29.93061224 Hypo-methylated NEPC|CRPC-Adeno DMRs chr837822530 37822575 1.70E−05 22.78888889 Hyper-methylated NEPC|CRPC-AdenoDMRs chr8 38241133 38241275 0.003113626 −37.36296296 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 41137893 41148108 0.000492768 −29.14269905Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 41571702 41571800 0.001694183−42.48703704 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 42947103 429471660.000324528 −34.04681373 Hypo-methylated NEPC|CRPC-Adeno DMRs chr843101980 43102561 4.95E−06 22.33819444 Hyper-methylated NEPC|CRPC-AdenoDMRs chr8 43132180 43132260 0.001694183 −22.24222222 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 43147389 43252192 0.007832634 −22.90622723Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 49018246 49230159 1.26E−12−26.03887634 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 49351073 493917263.27E−07 −26.33167454 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 4962891849675312 4.20E−05 −21.32012783 Hypo-methylated NEPC|CRPC-Adeno DMRs chr849718100 49778204 5.16E−09 −21.23006633 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 49783232 49783262 0.000549237 20.96031746 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 49783548 49826443 1.50E−07 −23.0173992Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 51413791 51605941 0.000220189−27.89756074 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 52721859 527219410.000549237 −24.19323308 Hypo-methylated NEPC|CRPC-Adeno DMRs chr853013436 53022287 8.52E−09 −27.09267998 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 53851773 53851807 0.000324528 28.97828947 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 54395986 54397093 1.70E−05 −29.07256653Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 55370662 55370710 0.00017613425.98305921 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 55370797 553710354.28E−07 23.38431495 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 5537205455372088 0.000101637 23.82931867 Hyper-methylated NEPC|CRPC-Adeno DMRschr8 55372219 55372294 0.00217795  27.33363065 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 55378973 55379838 2.68E−23 29.38632166Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 55380107 55380186 4.74E−0529.38860118 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 55382681 553831832.99E−15 24.6062471 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 5601410556014265 7.53E−06 23.2364931 Hyper-methylated NEPC|CRPC-Adeno DMRs chr856015215 56015256 2.94E−06 21.6254085 Hyper-methylated NEPC|CRPC-AdenoDMRs chr8 57069739 57070014 6.33E−06 21.27477314 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 57107106 57111144 0.000348917 −32.23990337Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 57358301 57358423 1.37E−0622.77092732 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 57358663 573587397.89E−07 28.79678363 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 5735907757359133 0.001883547 21.38636364 Hyper-methylated NEPC|CRPC-Adeno DMRschr8 57359210 57359677 4.85E−07 25.97544034 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 58055301 58055505 3.03E−07 24.44324943Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 59138019 59208728 9.09E−05−21.76456299 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 59231078 592311320.001694183 27.86754386 Hyper-methylated NEPC|CRPC-Adeno DMRs chr861936439 61990489 0.000263522 −34.99536842 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 63161560 63161698 8.08E−07 21.24536341Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 63781881 63895905 0.00222033 −23.47716165 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 65281783 652825547.50E−07 21.76033835 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 6528268065283663 5.22E−06 24.8296479 Hyper-methylated NEPC|CRPC-Adeno DMRs chr865490204 65492053 4.78E−07 20.79174339 Hyper-methylated NEPC|CRPC-AdenoDMRs chr8 66876254 66928541 0.000549237 −21.41461988 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 67090538 67090588 0.000176134 −23.46590557Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 68349486 68386618 5.17E−06−28.47749867 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 68391116 687133352.39E−06 −25.58820244 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 6877978168858398 5.36E−06 −45.11140351 Hypo-methylated NEPC|CRPC-Adeno DMRs chr868877185 69205787 1.70E−08 −39.25024889 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 72756051 72756111 6.91E−08 23.32697368 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 77595300 77832645 5.16E−07 −21.93259846Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 78015287 79374462 1.12E−09−37.25030795 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 81213465 812137240.000200814 −25.23315789 Hypo-methylated NEPC|CRPC-Adeno DMRs chr886440217 86569170 0.000148945 −34.42812714 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 87094225 87354341 4.14E−05 −26.55019952Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 96186989 96187034 0.001694183−61.18140838 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 96835985 969578073.79E−05 −30.94064536 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8101479899 101506734 0.003327791 24.25134589 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 104117790 104118252 0.000549237 −45.44586466Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 105645352 1056454190.003113626 −29.70921053 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8107600340 107637181 0.009458442 −36.5162768 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 110986149 110986669 0.001255081 23.20994152Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 116382702 1164485580.000975454 −20.41077694 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8116679744 116679835 5.01E−05 34.79692982 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 117172975 117300476 0.000581135 −20.66118421Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 119122182 119123162 9.74E−06−20.65010121 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 119270296119299844 0.000484821 20.40695489 Hyper-methylated NEPC|CRPC-Adeno DMRschr8 119346995 119630970 5.83E−06 20.80061505 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 121206379 121357766 0.001228429 −25.82458751Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 121567734 1218228910.000164003 −27.44174663 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8121878018 122180408 6.80E−07 −32.68393901 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 123616475 123655595 0.001549499 −20.33708882Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 128681344 1287046650.005239183 −28.59641929 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8131033464 131033693 0.000303685 28.92748538 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 131964088 132051742 2.07E−05 −24.30661376Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 132053079 132054680 2.44E−0721.25462751 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 134334295134390777 6.45E−06 23.48293074 Hyper-methylated NEPC|CRPC-Adeno DMRschr8 135728694 135734663 0.004750844 −33.27154605 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 140714605 140716218 2.74E−37 −24.01956976Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 140818431 1408185860.001545937 −43.47343577 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8140854221 140855177 0.004750844 −21.53007519 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 140859734 140860240 3.12E−07 −39.04258328Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 140888175 140893308 1.55E−06−38.25438596 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 140929804140931477 1.37E−06 −41.25035505 Hypo-methylated NEPC|CRPC-Adeno DMRschr8 141057225 141057521 7.87E−11 −41.89473684 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 141172065 141208733 0.001600753 20.31571207Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 141347658 1413477100.000176134 −47.75352444 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8142157126 142157247 1.70E−05 39.78210526 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 142187405 142189600 0.002432731 −25.09005848Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 142230701 142231546 4.59E−0629.44081384 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 142287046142287358 6.50E−07 −36.90443213 Hypo-methylated NEPC|CRPC-Adeno DMRschr8 142292238 142292320 0.001694183 −39.36754386 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 142378082 142380311 9.82E−05 −30.31659919Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 142729064 1427330520.002174767 22.99073513 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8142735997 142736179 0.002976353 30.04285714 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 142857802 142858608 0.003113626 −30.82116228Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 142986649 1429867870.001694183 −27.68630604 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8143070468 143073102 0.003977693 21.28416179 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 143227736 143227970 1.78E−05 28.73136671Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 143237761 1432401160.000324528 22.55460526 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8143375846 143376371 1.94E−06 −22.97604428 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 143395943 143396417 0.000101637 36.03625731Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 143420067 143424381 3.82E−06−27.72003533 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 143574852143574995 0.001694183 −23.15789474 Hypo-methylated NEPC|CRPC-Adeno DMRschr8 143611978 143612251 5.36E−06 −30.31071603 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 143776517 143781748 1.86E−06 −29.86809211Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 143854034 1438548860.000124569 −27.48467697 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8144153728 144155326 5.08E−07 −33.6406981 Hypo-methylated NEPC|CRPC-AdenoDMRs chr8 144269928 144270805 7.47E−05 −21.38011696 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 144551891 144554130 5.68E−05 −22.36310983Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 144572979 1445737310.000348917 −23.12834725 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8144597094 144598983 0.005899637 −26.05497076 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 144640310 144640858 3.40E−14 −25.97145642Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 144676049 1446761520.000549237 −35.33333333 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8144872811 144872958 7.58E−08 −33.68888889 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr8 144949825 144951803 4.65E−07 24.157714Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 145023500 145025047 2.20E−1120.34282365 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8 145028177145028481 0.00053414  21.5689333 Hyper-methylated NEPC|CRPC-Adeno DMRschr8 145045257 145046910 0.00222033  26.45504386 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 145123622 145125045 0.007249297 −20.62464146Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 145559841 1455602040.002362173 −20.19173629 Hypo-methylated NEPC|CRPC-Adeno DMRs chr8145725616 145728631 3.12E−14 34.06405456 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 145758493 145758729 0.000231593 −29.23278061Hypo-methylated NEPC|CRPC-Adeno DMRs chr8 145804895 1458051230.000549237 36.83333333 Hyper-methylated NEPC|CRPC-Adeno DMRs chr8145871451 145871563 0.001545937 20.8414903 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr8 145987889 145988113 5.50E−05 −44.52345679Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 235788 439410 3.93E−07−22.8038697 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 441358 4414240.001694183 −23.83564815 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9842531 842781 6.99E−06 20.17777778 Hyper-methylated NEPC|CRPC-Adeno DMRschr9 842800 949018 0.002592833 −32.05982906 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 971454 972033 3.03E−05 29.51770452Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 1509658 1637477 5.50E−05−35.56463326 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 1667754 20097009.61E−06 −39.61967893 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 67160796717227 0.000275281 −24.29486656 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 10285888 10583640 1.01E−08 −27.56288032 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 21402547 21559374 1.00E−05 23.75232526Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 33750285 33750553 0.003090185−23.41535088 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 34624621 346246510.003327791 29.4786152 Hyper-methylated NEPC|CRPC-Adeno DMRs chr935791556 35791983 2.77E−09 31.25503289 Hyper-methylated NEPC|CRPC-AdenoDMRs chr9 36868247 36868435 0.000732983 −34.24880383 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 37959915 37963171 0.000184724 −21.5122807Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 38687298 38687897 1.42E−08−37.80715927 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 44178017 442191469.42E−05 −25.81673547 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 4488244345119196 1.48E−07 −34.12267738 Hypo-methylated NEPC|CRPC-Adeno DMRs chr966837865 68291949 8.84E−05 −24.46116765 Hypo-methylated NEPC|CRPC-AdenoDMRs chr9 68370862 68408947 0.000111341 −25.01299799 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 68409254 68410815 0.000312629 −20.63678191Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 71835666 71835938 1.55E−06−31.76680058 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 72027151 720273670.00678631  21.88581302 Hyper-methylated NEPC|CRPC-Adeno DMRs chr973002759 73002844 0.000832692 −30.6125731 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 78694263 78739587 2.46E−05 −25.44504644Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 78803362 78820992 0.000488426−24.02002064 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 80833961 808340930.003327791 −21.36907895 Hypo-methylated NEPC|CRPC-Adeno DMRs chr989574420 89626722 1.76E−05 −26.93626714 Hypo-methylated NEPC|CRPC-AdenoDMRs chr9 89773622 89920198 2.37E−08 −33.99632622 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 90498352 90559236 3.54E−05 −24.76810864Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 90626773 90682265 0.000337166−21.52256803 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 90890419 909765635.89E−05 −20.14055777 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 9132141691321931 1.33E−07 −46.08765951 Hypo-methylated NEPC|CRPC-Adeno DMRs chr992299887 92300948 0.003808143 −24.82050812 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 92858175 92860846 0.000392904 −38.6157856Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 93955387 93956209 3.70E−11−35.12479821 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 96592222 965923010.001694183 −27.4214425 Hypo-methylated NEPC|CRPC-Adeno DMRs chr997022286 97022355 4.74E−05 22.74510234 Hyper-methylated NEPC|CRPC-AdenoDMRs chr9 97837065 97839657 0.006847068 −29.29022556 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 98032567 98032640 0.000549237 −41.61353383Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 98256445 98257335 0.000340762−36.66137009 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 98527342 985274260.000549237 −31.04511278 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9100593582 100593928 0.001883547 −24.11961722 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 100617008 100620147 5.54E−17 23.37620992Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 102021680 102022088 1.77E−05−22.39809863 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 110350021110350209 1.37E−07 −20.70466792 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 111610649 111617412 2.94E−06 −24.25595046 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 112705330 112705396 0.001694183 20.62614768Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 113801112 113801271 1.17E−0833.14948078 Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 115618930115619278 0.002094266 −31.81242922 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 116372198 116372423 0.001694183 −52.99385965 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 116411417 116411676 0.000926684 −50.38325163Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 117022084 1170223300.000549237 −39.03575606 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9124344198 124345027 0.002023529 −26.45813434 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 124620028 124621382 0.001694183 −56.61017157Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 124989640 124989856 3.68E−07−22.84333641 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 126348976126353706 0.000176134 −24.52059415 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 126887818 126888262 2.91E−05 −32.2263044 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 127020722 127021162 0.000332311 27.10493421Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 127105180 127106084 1.98E−05−42.55849791 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 127265611127266113 7.77E−09 25.29416063 Hyper-methylated NEPC|CRPC-Adeno DMRschr9 127582708 127583244 0.001532655 −21.30381335 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 127596062 127597353 0.005737741 −34.31198769Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 128160070 1281601270.001694183 −44.082846 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9128819673 128819970 0.001694183 −49.0369281 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 128984730 128985520 0.001365349 22.25804151Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 129276918 129276962 1.70E−0530.21645898 Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 129294453129296986 0.003113626 −26.66141498 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 129373240 129373646 0.000200845 21.3574269 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr9 129895856 129896382 5.50E−05 −52.55407207Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 130292451 130292760 1.70E−05−31.25087719 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 130307535130313386 0.000106805 −35.34883041 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 130505114 130505156 0.001694183 −38.98637372 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 130580413 130580501 0.001694183 −44.4696533Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 130712087 130713170 2.14E−05−25.51484962 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 130737328130737541 0.000176134 −36.47810673 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 130829121 130829270 0.00222033  −32.28092105 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 130891603 130894541 0.003113626 −27.67390351Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 131127059 131127544 5.34E−09−29.69706266 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 131217381131217558 0.003525992 −38.99437135 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 131219584 131219746 0.009458442 −30.69057018 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 132071141 132071528 0.00040075  −26.50106326Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 132178565 132178692 1.98E−05−24.84628715 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 132460627132472157 1.02E−05 −34.81892272 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 132549343 132549504 0.000549237 −32.08045113 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 133297469 133298065 3.19E−08 −36.73218476Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 133411323 1334118720.00769092  −23.91554581 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9133770973 133771975 0.001274051 −26.12502089 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 133776970 133777219 3.40E−05 −25.87092471Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 133788538 133788804 5.34E−09−22.67605882 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 133895277133895368 0.001694183 −39.77105263 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 134183544 134183612 5.17E−06 −30.82248804 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 134199569 134204978 0.005297267 −27.40371763Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 135089560 1350896920.001694183 −45.04003268 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9135374946 135381835 1.09E−05 −27.67350533 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 135419388 135419528 0.000282282 −25.27071994Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 135608716 135608804 5.17E−06−38.83574087 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 135678010135680846 0.000277187 −25.01223893 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 136007377 136008637 5.14E−05 −46.86939748 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 136038775 136038972 1.42E−05 23.5453051Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 136046683 1360521810.000152004 −24.81713005 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9136063379 136075203 0.000183183 −22.49033463 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 136290366 136290519 0.001694183 −36.98611111Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 136324006 1363242570.000200845 −42.48789474 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9136399391 136401261 8.50E−13 −20.53795771 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 136529391 136529512 0.003327791 −44.80942982Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 136740461 136755525 8.90E−06−21.18169757 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 136814815136816138 8.43E−06 −28.3933114 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9136834290 136838619 2.58E−07 −30.66062486 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 136919324 136921209 0.003932932 21.68233779Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 137125231 1371264860.00064342  −22.05933723 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9137128024 137140495 2.19E−05 −21.14350639 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 137174162 137177197 0.004806912 −21.80033986Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 137186596 137190446 3.44E−07−29.82000646 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 137200887137211391 2.54E−06 −23.1531005 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9137239316 137240645 8.71E−07 −31.32173913 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 137247145 137250725 0.000148223 26.32691971Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 137251149 1372514440.000332001 −26.0626032 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9137266220 137267513 0.000288502 33.11403509 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr9 137305867 137306372 2.91E−06 −43.06008772Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 137354301 1373563950.001229862 −21.06754386 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9137366430 137367425 0.004215557 21.6186565 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr9 137529736 137533113 0.001506981 −21.74190946Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 137756555 137804526 6.71E−14−27.80637636 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 137880070137881685 0.002859601 −27.16421053 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 137882878 137883201 8.71E−07 −23.31157241 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 137937734 137962160 7.10E−08 −34.27760615Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138010698 1380117730.00027623  −20.57776058 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9138018421 138019435 0.000200845 −27.26116959 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 138193278 138193486 0.001065261 −26.79298246Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138220976 1382218600.001814062 −33.75757985 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9138233063 138233203 0.000176134 −33.29210526 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 138268102 138268783 0.000337664 −31.44040045Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138272060 1382723500.000700082 −32.93145933 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9138294954 138295229 0.004291094 −21.78421053 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 138330554 138337813 0.000619184 −27.43416409Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138508627 138550678 6.09E−06−20.00405383 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138597380138603436 0.00015998  −24.30320245 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 138609320 138611468 9.26E−06 −25.92572255 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 138614331 138616090 0.002227988 −20.41453982Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138661452 138662609 1.78E−13−26.8234635 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 138675638138678361 2.94E−12 −21.09658034 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 139038780 139039138 0.00222033  −25.42872807 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 139060477 139062568 0.008187764 26.53779904Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 139096816 139097662 7.90E−1027.98502796 Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 139141928139142089 0.000303685 −33.82079504 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 139155510 139155682 0.000549237 −27.21695906 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 139396824 139397578 5.69E−07 −22.17925804Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 139400169 139401496 4.91E−09−20.60446738 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 139403170139403460 0.000439429 −26.66684211 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 139409321 139411441 7.02E−09 −21.25608103 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 139573150 139574082 0.000889013 38.90327549Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 139584634 139585969 5.47E−07−23.21097661 Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 139635430139635760 0.00217795  −23.81285714 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 139648148 139649508 9.70E−06 −22.5070255 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 139658444 139659183 0.005737741 −43.5460213Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 139672072 139672185 5.17E−0620.70924375 Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 139750206139751887 1.11E−05 −22.62578586 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 139873366 139873497 1.27E−05 26.33965976 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr9 139902068 139904811 1.71E−19 −31.34162092Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 139907751 139907914 9.81E−0524.99418184 Hyper-methylated NEPC|CRPC-Adeno DMRs chr9 140175388140175436 1.55E−06 −23.27079858 Hypo-methylated NEPC|CRPC-Adeno DMRschr9 140266895 140267338 0.000371055 −20.58553606 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr9 140322962 140324976 1.63E−08 −33.79904201Hypo-methylated NEPC|CRPC-Adeno DMRs chr9 140373567 140375030 7.07E−07−37.4128193 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 527070 5277751.43E−05 −24.46527778 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 676740676826 0.000549237 −61.39158663 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 1259532 1260038 0.000489849 22.31520468 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 1477190 1477331 0.001694183 −57.73962848Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 1594637 1595786 7.21E−07−22.14319889 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 1641115 16411730.000176134 −37.97079678 Hypo-methylated NEPC|CRPC-Adeno DMRs chr101889183 1920662 0.004693517 −23.84131909 Hypo-methylated NEPC|CRPC-AdenoDMRs chr10 2432059 2538391 5.79E−07 −35.25457283 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 2932371 2932614 0.000303685 −28.612044Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 2960341 2964800 0.001694183−24.39995136 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 3059801 30718770.001694183 −30.66081011 Hypo-methylated NEPC|CRPC-Adeno DMRs chr103168192 3171146 0.000292068 −20.18284905 Hypo-methylated NEPC|CRPC-AdenoDMRs chr10 3421354 3441107 0.001065261 −35.79956045 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 3710872 3711105 0.001802623 25.86559536Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 4908800 4983807 0.001883547−22.70517169 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 6622144 66225093.16E−11 24.62232053 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 72533287299936 0.00217795  −25.62659541 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 7317076 7439794 5.28E−11 −23.97294806 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 7667450 7702969 1.72E−05 −37.20499746Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 8087190 8087423 0.000200845−22.73597695 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 1105946711060757 1.81E−50 28.59533291 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 11950223 11950312 0.001694183 −25.97258772 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 12633277 12633387 0.001694183 −47.75243665Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 13726467 13726635 5.17E−06−29.9553429 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 13862745 138631183.73E−07 −33.73830931 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1016562018 16562311 5.49E−12 26.08136629 Hyper-methylated NEPC|CRPC-AdenoDMRs chr10 17879085 18385449 5.01E−05 −24.95590203 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 20116635 20233812 1.70E−05 −28.95327485Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 20251480 20497727 0.004652598−24.20573221 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 2346030023460458 0.001694183 29.28596491 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 23462460 23464044 7.43E−12 24.47820632 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 23481419 23481657 3.06E−07 35.41544626Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 24020414 24497873 6.39E−06−25.30129265 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 2454407924547683 0.003652661 −30.04891555 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 24567210 24609833 2.74E−05 −34.42947921 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 24635159 24805452 2.21E−10 −26.04963223Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 25246662 25452380 3.23E−06−29.2184255 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 25908294 259351970.000337664 −33.8094152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1025990759 26032492 2.53E−05 −30.43095934 Hypo-methylated NEPC|CRPC-AdenoDMRs chr10 26223207 26223337 5.71E−06 26.56326355 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 26506583 26506684 0.002376793 24.21839447Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 27181801 27205423 8.64E−05−25.67930627 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 2803431728034444 0.00367696  26.65378788 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 28034591 28034646 0.000197871 20.92361111 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 28068843 28252767 1.12E−07 −27.3188231Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 29874713 29874760 0.003113626−41.54166667 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 3198665931986988 5.17E−06 −39.97460988 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 32038939 32039037 0.004693517 −25.10192147 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 36292146 36813242 9.76E−13 −26.1925466Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 36909428 36917352 0.001694183−24.25921749 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 3710003737122732 0.000154148 −26.52591093 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 37611614 37869516 1.04E−06 −22.42667054 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 42971733 42972953 0.004693517 −21.82807837Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 43539337 43540899 4.20E−05−33.31139733 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 4372823043732839 0.009458442 −26.71296296 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 43754321 43761270 0.000397342 −20.65451047 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 44005336 44039369 0.009285355 −25.90823804Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 44843664 44877823 4.33E−05−24.04709003 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 4488099644881165 0.000488426 21.15452092 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 44910283 44968454 0.003977693 −21.30931774 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 45082817 45193328 2.01E−06 −23.43216882Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 45471259 45473599 5.34E−05−33.02589286 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 4567598745693533 4.46E−06 −28.76102602 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 47008176 47008252 8.96E−05 22.40864662 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 47098668 47122554 1.70E−05 −22.01647661Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 47555758 47627503 1.04E−06−28.71959518 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 4767999047685634 1.43E−05 −27.4970485 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1047749367 47757973 1.70E−05 −30.66431704 Hypo-methylated NEPC|CRPC-AdenoDMRs chr10 50605557 50605614 0.000184724 −23.02429003 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 50815083 50817377 3.72E−05 26.55161915Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 50819637 508197850.00039263  27.67192982 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1050976131 50977136 1.91E−15 28.88728862 Hyper-methylated NEPC|CRPC-AdenoDMRs chr10 54073802 54074386 9.29E−13 20.07016728 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 55636108 55651945 5.17E−06 −28.01961722Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 57390896 57391102 6.32E−0824.50604773 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 5960185659668238 0.000104758 −22.76927166 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 62760612 62760668 0.001694183 −26.46081871 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 65801548 65801594 0.001012154 26.55357143Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 67815403 68247281 6.16E−06−23.99133131 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 6846241369263006 2.51E−09 −31.81456618 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 71328723 71329430 3.40E−10 34.55063926 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 71334685 71336242 0.000176134 27.14658173Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 71658478 716609410.009682706 −21.23998538 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1071892103 71892769 4.50E−23 −31.75503977 Hypo-methylated NEPC|CRPC-AdenoDMRs chr10 72141269 72141388 0.001694183 −27.43327068 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 72695469 72695680 0.001065261 −26.92358674Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 72764199 72769228 3.40E−10−32.17307853 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 7297359272977379 1.07E−18 −23.4529645 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1073221938 73221983 0.001694183 −47.1376849 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 73466474 73466728 3.47E−07 −26.95398479Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 73565665 73565861 0.00092668424.39837535 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 7376841573776944 0.000721524 −34.45980335 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 77794566 77811143 7.47E−05 −27.97736007 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 79276497 79291440 0.000153872 −33.84502924Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 79702851 79702997 0.005737741−29.29264706 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 7997863879978936 0.000176134 −39.26150348 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 80673359 80673790 0.009274146 −26.93704678 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 81266609 81267373 1.22E−05 −47.97986037Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 82442236 82712731 2.09E−09−28.85927418 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 8281077082959528 4.59E−06 −28.00263767 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 83025089 83044825 0.005737741 −33.24573587 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 83635030 83636333 1.79E−14 22.19552951Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 85321507 853411000.000549237 −24.63125 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1088408252 88412839 0.003327791 −29.78355801 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 88428117 88430347 1.03E−05 −46.81815991Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 89167930 89189130 0.00169418323.06481481 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 9129553391308429 4.76E−13 24.29759861 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 97466652 97466951 0.002376793 −34.83435907 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 98808702 98808813 0.000549237 −56.32017544Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 98894117 98894245 0.003525992−37.51719577 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 9973441699783986 2.48E−08 24.23893182 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 102419262 102419303 0.001694183 31.31370092 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 102475441 102475556 0.00041315  27.42522974Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 102620812 1026267490.001549499 −33.39010824 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10103536274 103536321 0.000542154 24.06356801 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 103603177 103603642 2.17E−06 28.88907731Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 106400259 106400309 5.50E−0523.28070175 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 106400657106401124 7.66E−06 23.12951945 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 106401291 106401323 5.01E−05 27.20317184 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 106401463 106401483 5.75E−05 26.79187552Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 108924195 108924503 3.69E−0827.73528644 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 108924579108924773 6.53E−07 30.72330634 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 110226159 110226465 0.000490451 20.40055137 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 111322897 111460079 8.46E−07 −27.12751861Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 112289991 112290305 1.02E−07−28.45394041 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 112553722112553780 0.001694183 −45.92744361 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 113050404 113882148 2.08E−05 −30.24059598 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 114051750 114051819 0.000176134 −21.02368421Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 114123381 1141234310.007136365 23.44511278 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10116061880 116061937 0.001694183 20.39242203 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 118387431 118387476 3.15E−05 23.72976608Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 118388135 1183927150.005737741 −21.2441242 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10118434404 118434551 7.69E−05 −21.79605263 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 118885687 118885838 5.45E−05 −22.91684211Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 118897464 118900329 5.31E−0921.7271224 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 119297477119301828 8.70E−09 21.87791904 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 119480788 119490967 0.008985252 −20.68752437 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 119589954 119590054 0.000549237 −46.70143742Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 121963962 1219694750.009458442 −21.20087719 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10123738257 123772457 3.10E−05 −23.49736842 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 124714365 124724110 0.002976353 25.93878323Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 124896793 124897211 8.60E−1025.1787139 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 124901913124905964 2.28E−18 28.68750524 Hyper-methylated NEPC|CRPC-Adeno DMRschr10 125650943 125651403 2.84E−14 25.08582325 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 125751936 125752100 0.003932932 26.17103543Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 125765718 1257657950.000549237 −25.60894954 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10126296003 126296287 0.002976353 −26.66617586 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 126538091 126539042 0.001802623 −21.08521303Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 126838125 1268408000.001745755 −22.21252724 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10127137319 127137384 0.000581135 29.45467836 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 127451738 127452093 1.70E−05 −22.54380117Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 128606018 1286072880.000286322 −30.36311551 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10128993561 128994030 7.36E−10 −21.13664045 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 129142456 129142649 0.000549237 −41.67067669Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 129535708 129535814 1.87E−07−22.56817279 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 130185305130203553 5.01E−05 −33.38336118 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 130726227 130726448 0.000220189 −31.66278564 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 130845594 130847047 0.001694183 −24.52300195Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 130911198 1309734170.000280041 −31.27098555 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10131041046 131076334 6.21E−10 −21.0904663 Hypo-methylated NEPC|CRPC-AdenoDMRs chr10 131195846 131213793 1.15E−05 −25.51999008 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 131449283 131450296 0.000291618 −20.53017265Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 131592555 131606696 8.77E−08−20.59090017 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 131609752131609826 0.001694183 −20.86403509 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 131667039 131668687 0.000549237 −25.47225785 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 131735410 131736014 0.007136365 −22.18479532Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 131771095 1317711980.002613955 23.28345865 Hyper-methylated NEPC|CRPC-Adeno DMRs chr10131771319 131771424 1.37E−07 22.28609023 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr10 132098756 132100151 6.53E−13 20.35492575Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 132968328 1329685120.000101637 −30.48451221 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10133047633 133047729 0.009274146 −22.70305814 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 134007458 134007540 0.000291618 24.62911184Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 134092121 1340957500.000155744 −30.35127692 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10134108428 134108672 7.69E−05 −41.02763158 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 134204570 134209887 2.90E−13 29.30860477Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 134251800 1342521520.000286322 −23.01988602 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10134280987 134281096 0.004750844 −35.26380289 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 134377300 134377491 1.55E−06 −28.07285575Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 134562574 134563201 2.20E−11−44.36843825 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 134589773134590261 3.68E−07 −33.7356989 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 134621538 134624084 4.23E−06 −21.84565763 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 134756822 134756852 0.000101637 20.61224821Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 134943406 134945484 1.76E−05−30.56223501 Hypo-methylated NEPC|CRPC-Adeno DMRs chr10 134945598134945659 0.000118201 −21.37587719 Hypo-methylated NEPC|CRPC-Adeno DMRschr10 134974407 134975410 5.02E−09 −21.93487051 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr10 135043917 135043927 0.005737741 25.96037582Hyper-methylated NEPC|CRPC-Adeno DMRs chr10 135044951 135045544 1.06E−06−23.55898696 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 197256 1975981.66E−09 −24.05792552 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 279404279705 3.81E−11 −20.83138652 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11528886 529684 0.000176134 −33.35620301 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 888359 888730 0.000168572 −24.1301208 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 1008216 1008447 1.33E−06 −21.91329774Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1011316 1011494 1.22E−05−29.04347923 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1034806 10351100.000732983 −29.5348219 Hypo-methylated NEPC|CRPC-Adeno DMRs chr111095846 1102571 3.41E−12 −23.46553807 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 1124352 1140480 4.05E−08 −25.0506208 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 1247404 1247533 0.000124569 −23.46807992Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1276645 1276744 0.009285355−24.68055556 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1312042 13133208.87E−06 22.917154 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 13568071356930 0.007136365 −20.3520259 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 1482302 1482428 5.01E−05 26.65070663 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 1585759 1585929 5.50E−05 −32.64197531Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1677611 1678911 5.50E−05−39.4591293 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1769228 17695031.06E−05 −29.18340259 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 18359001844729 1.56E−05 −27.06006613 Hypo-methylated NEPC|CRPC-Adeno DMRs chr112033787 2035368 1.30E−09 −34.91938217 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 2036865 2037815 3.36E−08 −39.42145171 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 2115657 2115907 0.002174767 −28.95748988Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 2180892 2184481 5.75E−05−21.95298591 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 2332094 23325690.003932932 −31.61576743 Hypo-methylated NEPC|CRPC-Adeno DMRs chr112337212 2385429 3.20E−05 −21.92916667 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 2400205 2411480 1.16E−08 22.97862376 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 2431518 2431628 0.000176134 −40.48435673Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 2495135 2495611 3.15E−05−41.46631579 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 2580748 25808140.000549237 −25.91151987 Hypo-methylated NEPC|CRPC-Adeno DMRs chr112595852 2596461 4.66E−05 −31.84636223 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 2673444 2683858 1.52E−05 −36.3245012 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 2871683 2871993 2.07E−07 −34.89968045Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 2891062 2891360 2.14E−07−22.3450509 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 2954496 29548252.46E−05 22.39635628 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 30711943071338 0.001694183 −28.19517544 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 3164341 3164534 0.004750844 −30.50736216 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 4298614 4339096 0.002927544 −24.53034534Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 4415245 4494345 0.000176134−24.59327216 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 8045759 80538720.00222033  −21.61059942 Hypo-methylated NEPC|CRPC-Adeno DMRs chr118336829 8337252 0.000106852 −23.90212097 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 10311436 10314121 0.001600753 23.30372807 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 11354115 11404893 5.50E−05 −31.39355722Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 11600197 11600245 0.007271222−62.53050303 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 1203002712030141 5.36E−06 20.2254386 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1113986005 13986311 8.65E−14 30.5497076 Hyper-methylated NEPC|CRPC-AdenoDMRs chr11 14277229 14284338 0.004652598 −26.73796992 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 15638098 15651213 0.004750844 23.41790936Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 15962841 15964430 5.94E−0824.42032668 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 1683669216836916 0.003652661 −20.65157895 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 17552955 17553237 0.004750844 −34.89400585 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 17757699 17784810 1.75E−06 22.24869066Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 18750201 187651020.000687445 −22.67991056 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1118802245 18812770 5.17E−06 25.84071755 Hyper-methylated NEPC|CRPC-AdenoDMRs chr11 20230414 20230483 0.000549237 23.49022556 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 22454301 22454399 0.002138478 30.68263158Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 30409847 30527670 8.05E−11−29.76928432 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 3068066031087495 6.82E−07 −21.56655405 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 32448409 32448774 4.82E−08 23.53344516 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 32451777 32451916 0.001802623 −31.55545113Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 32454919 32458468 3.42E−2421.33678094 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 3364011033640180 0.000176134 23.67324561 Hyper-methylated NEPC|CRPC-Adeno DMRschr11 33667283 33667578 2.27E−06 −27.6377193 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 34852392 34888583 0.001694183 −28.67871067Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 36476272 36477308 3.47E−07−22.60740741 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 3712036537414157 0.000153872 −22.91828453 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 41330447 42895559 5.01E−30 −32.44839382 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 44007973 44013893 0.002336248 −28.45933014Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 44066442 44072905 0.000160831−20.47175546 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 4461465544614968 0.000549237 −21.21823308 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 44630409 44630491 0.001694183 −53.75263158 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 44654458 44661400 0.005737741 33.87792398Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 44899770 44916272 3.19E−05−35.34866759 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 4635429246354965 2.53E−30 −20.78424984 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 46384984 46385447 7.22E−05 −21.93537275 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 47736766 47736972 2.98E−08 −22.22385509Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 48967609 48990351 0.002859601−33.651368 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 57135958 571361240.003525992 −39.39717349 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1157834719 57894793 7.00E−05 −22.05773212 Hypo-methylated NEPC|CRPC-AdenoDMRs chr11 57912316 58297474 1.61E−06 −26.91984555 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 59319776 59319914 5.50E−05 26.93144899Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 59787973 59840685 7.93E−06−23.46543862 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 5986000459875844 0.005574264 −21.57237981 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 60933902 60934092 0.001694183 −37.65423977 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 61300522 61300774 1.82E−05 −28.59911953Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 61449844 61449961 0.001694183−44.58991228 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6159528561596307 7.50E−16 −20.84623111 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 62650164 62650416 0.003113626 32.88596491 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 62801810 63029732 0.006597219 −24.49543999Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 63786577 63788767 3.60E−05−27.60058234 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6381256663812847 0.00041315  −51.71783626 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 63851466 63853046 0.001197874 21.71052632 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 63900942 63902686 0.000348917 −23.91709973Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 63987709 63990142 0.00209426628.46107456 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 6400327164003502 1.55E−06 −36.59923246 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 64119978 64120743 1.65E−05 −62.37964396 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 64219570 64313871 1.33E−07 −26.04105661Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 64331702 64331800 0.000549237−24.72368421 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6436648364373429 0.001809257 −20.29678363 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 64950007 64951046 0.003063309 −20.8919551 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 65000766 65000941 0.007136365 −22.99550961Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 65089430 65089601 0.00222033 21.36842105 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 6530602465306225 0.001694183 20.13637459 Hyper-methylated NEPC|CRPC-Adeno DMRschr11 66083698 66084085 0.00203966  −26.63807667 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 66101563 66101701 0.000220189 −21.19816033Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 66257043 66257274 0.000667554−34.50994152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6631569366315846 0.001694183 −20.84661306 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 66453951 66454138 0.001694183 22.96881092 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 66812205 66812371 0.000549237 −21.18295739Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 67186073 67186579 1.33E−0525.83651157 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 6808415268084612 0.009822962 −24.67012228 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 68200443 68200692 0.000118331 −25.72232665 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 68417770 68418482 0.000711935 −23.14181287Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 68431815 68434011 2.35E−05−24.69558897 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6861022268610744 0.000151874 22.01701223 Hyper-methylated NEPC|CRPC-Adeno DMRschr11 68762226 68762360 0.002094266 −24.95000334 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 68772956 68773145 1.94E−06 −25.28082707Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 68789480 68790641 0.000667554−25.50926772 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6896774068968440 3.88E−10 −42.31946533 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 68985397 69002032 0.003408779 −29.13553756 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 69206477 69209067 1.13E−06 −32.78438298Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 69259741 69259796 0.00017613428.63662281 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 6951212269514111 0.000484821 −28.56155186 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 69551654 69557572 0.004215557 −21.78091018 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 69630589 69631356 0.003063309 −21.24892335Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 69678772 69679989 0.001931256−20.90558214 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 6971829569794751 8.37E−09 −23.90724236 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 69800935 69807960 4.65E−06 −26.26264376 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 69817895 69818517 0.004750844 −29.11052632Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 69980867 69981924 0.000340762−28.00964912 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 7007599570090124 5.19E−05 −22.04591053 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 70475562 70475813 0.001267128 −20.77733918 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 70731820 70733243 8.61E−07 −35.33116472Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 70795361 70796081 0.006890179−40.0360705 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 70862292 708624430.000176134 −50.67967836 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1171022313 71033706 0.000716333 −21.6163198 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 71080061 71100235 0.006785531 −22.50977851Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 71937476 71940339 0.005456645−35.41666667 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 7230155872301793 3.84E−07 25.86706419 Hyper-methylated NEPC|CRPC-Adeno DMRschr11 72975546 72975797 3.26E−12 −23.87120743 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 73359291 73359391 0.001694183 −27.13596491Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 73371753 73372006 3.68E−0736.36822213 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 7369215573693060 0.000549237 −34.40233918 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 74394246 74394995 6.36E−10 −26.21680737 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 74408157 74408222 0.001694183 22.85263158Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 76463916 764640040.000176134 22.95328947 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1176885661 76885948 0.003592038 −25.63508772 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 81455809 81455852 0.001694183 −25.48613732Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 81662718 81698031 4.34E−06−27.35639901 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 8211525082212627 7.07E−07 −21.67440476 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 89269440 89300467 0.000549237 −30.88646617 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 95032701 95032880 0.001694183 −44.70138889Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 100998056 100998492 1.30E−1824.34713336 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 104034648104035058 3.71E−18 25.11910083 Hyper-methylated NEPC|CRPC-Adeno DMRschr11 107529806 107622253 3.15E−05 −35.32 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 111265963 111266121 0.000549237 −44.52656642Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 112349185 1123706380.000581135 −26.21907895 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11113145782 113145874 0.001694183 −29.30175439 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 115829505 115830431 4.46E−09 −46.42757816Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 116033407 1160338230.000774257 −28.90427022 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11116069951 116078722 0.002692265 −34.67849659 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 118662661 118663291 1.78E−10 22.84933266Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 119050525 119053027 5.50E−05−32.04736842 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 119943954119944133 0.009458442 −27.19473684 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 122344639 122427446 0.006890179 −24.65322566 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 122910859 122910995 0.000832692 −28.22858187Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 123380626 1233809390.002094266 −31.47205978 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11123543120 123543183 0.000488426 −24.69267907 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 124757118 124765703 2.91E−09 −31.44834569Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 125141267 1251795800.005332682 −20.66142988 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11125277805 125291686 1.09E−07 −28.34558491 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 125299752 125329373 1.15E−05 −28.77434211Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 126033295 1260335440.004750844 −28.26513158 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11126235718 126236163 0.000549237 35.20710109 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 126284669 126285823 0.001694183 20.0622807Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 126422411 1264450800.000457314 24.61354288 Hyper-methylated NEPC|CRPC-Adeno DMRs chr11128321682 128321859 1.77E−05 −42.71965628 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 130275533 130287404 1.59E−07 −20.76761312Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 130332450 130335609 5.84E−05−25.01082215 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 130357360130431436 1.45E−06 −20.44141589 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 130492954 130495819 0.004750844 −24.18009815 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 130518520 130700487 3.05E−05 −21.60884947Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 131559033 131561244 2.55E−07−26.61980134 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 133657404133657473 0.007136365 24.72556391 Hyper-methylated NEPC|CRPC-Adeno DMRschr11 133702710 133702924 0.000300362 21.28247238 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 133800810 133801158 0.001274051 24.43842105Hyper-methylated NEPC|CRPC-Adeno DMRs chr11 133896652 133902768 9.80E−07−42.11296508 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 134237849134237923 0.000176134 −30.69868421 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 134408805 134442817 0.000550461 −21.88684211 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 134454691 134509057 4.03E−10 −29.70304349Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 134514472 1345256960.009285355 −20.94650037 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11134535135 134631475 5.71E−08 −22.81926463 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 1929412 1930336 0.001802623 −21.63242911Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 1957458 1957589 0.000549237−42.68766033 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 2955201 29553410.003113626 −21.55847953 Hypo-methylated NEPC|CRPC-Adeno DMRs chr123239851 3240382 5.50E−05 −29.58219623 Hypo-methylated NEPC|CRPC-AdenoDMRs chr12 3297463 3297904 0.002362173 −20.44399541 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 3386251 3386437 0.001694183 33.99193756Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 3728462 3728610 0.000953892−36.09071637 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 4273900 42739884.74E−05 22.08920787 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 43782684378441 0.003327791 23.10923653 Hyper-methylated NEPC|CRPC-Adeno DMRschr12 4480040 4492995 0.001802623 −24.41991089 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 4918595 4919476 3.43E−16 25.53059903Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 5153443 5153914 1.21E−0924.3617037 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 7260660 72617101.95E−09 −23.85266265 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 75928157593008 4.45E−11 36.89176718 Hyper-methylated NEPC|CRPC-Adeno DMRs chr127910505 7916226 0.007136365 −28.11260294 Hypo-methylated NEPC|CRPC-AdenoDMRs chr12 8033840 8060755 0.001125639 −22.14273183 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 8125786 8145716 0.000291618 −24.09052935Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 10564044 10564106 0.000549237−41.94377611 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 1304592413052225 0.006785531 −32.68676901 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 14134272 14134868 3.70E−06 24.60202777 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 22094270 22095220 1.37E−12 26.32084086Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 22161261 22189931 5.75E−05−34.20453216 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 2232398522473588 0.000291618 −29.4807557 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 24416016 24679019 7.89E−07 −29.69746387 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 26379784 26379996 7.44E−08 −32.5361403Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 28123502 28123939 2.25E−0623.03826232 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 2897421329291435 0.001644274 −22.26318324 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 29324853 29426775 1.08E−06 −33.5428127 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 31231771 31256748 0.008624828 −28.22240881Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 33591887 33592924 1.41E−1827.20230921 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 3448870434488755 0.007136365 32.43233083 Hyper-methylated NEPC|CRPC-Adeno DMRschr12 34495756 34495974 0.004750844 27.03881579 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 34503133 34503177 0.003525992 31.60877193Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 38546746 385469470.001694183 20.34339525 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1238555941 38557458 0.008187764 −25.12353958 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 38557543 38596711 0.000153872 −30.24695906Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 39879325 39992364 2.91E−06−35.91579521 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 4061843940618848 1.00E−09 31.94746304 Hyper-methylated NEPC|CRPC-Adeno DMRschr12 43945381 43945875 1.25E−05 25.86814404 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 44896639 45135204 8.86E−08 −24.87393146Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 49659767 49659927 9.54E−05−23.40150929 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 5226268452263396 2.25E−07 −24.79140078 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 52281891 52283315 0.00040075  −26.09894737 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 52300763 52301041 0.00223107  20.12497642Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 52418969 524191890.001065261 35.45707146 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1252519143 52519213 0.003113626 −26.82004183 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 52569828 52569994 0.005737741 −25.48732943Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 52585500 52585696 4.65E−07−31.23772412 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 5300296053040135 2.07E−05 −23.02156115 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 53454354 53454977 0.004705671 −30.90281955 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 53590422 53590524 0.000176134 −23.62171053Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 54343828 54344059 0.001109725−25.97410952 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 5439696454398941 3.19E−06 20.11761266 Hyper-methylated NEPC|CRPC-Adeno DMRschr12 54850591 54852450 0.009458442 −20.33044591 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 63187323 63193732 0.007136365 22.79398496Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 66026204 661146970.000176134 −45.5003655 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1266123203 66123293 0.000721524 24.33880572 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 66135121 66136135 8.12E−20 34.32846692Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 66138108 66213858 3.81E−06−33.47089292 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 6626221466266284 0.000549237 −53.15215165 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 66582856 66583084 1.11E−08 21.84646773 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 70970350 70970388 0.001694183 22.08968254Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 75089303 752002690.00060921  −20.09103099 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1285306324 85306813 0.000259019 20.03145196 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 85473092 85581480 0.000176134 −39.77489949Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 86237414 86237858 0.000209051−29.3362706 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 96602628 966137680.001694183 −22.47953216 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1297441750 97532354 0.007136365 25.41561256 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 99139467 99142838 0.000926684 30.58315789Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 103358856 103407000 3.01E−0622.86010284 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 105131873105136501 0.005574264 −34.00047847 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 106506138 106531772 0.009458442 −27.55740086 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 108029778 108040091 1.79E−07 −33.56366625Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 108199853 1082306110.000100851 −33.89356725 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12108237526 108237723 4.03E−08 24.2011306 Hyper-methylated NEPC|CRPC-AdenoDMRs chr12 108238515 108238708 4.45E−08 23.4222488 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 109948226 109948310 0.000549237 −29.64912281Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 110115344 1101178750.004686715 −22.50945992 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12111394556 111404204 0.000711935 −27.1777128 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 111506197 111515269 3.44E−08 −20.85550682Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 111558050 1115582310.004750844 −33.29197995 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12111687022 111703556 0.004750844 −31.12269576 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 111715854 111725628 7.05E−10 −33.82908163Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 112548914 1125500640.005737741 21.92966792 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12113914255 113914319 5.17E−06 24.71100478 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 113917518 113917543 0.001694183 28.05789474Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 114075873 114076046 2.52E−1020.08923289 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 114116378114123214 0.000492768 −32.21626794 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 114282283 114282968 0.000549237 −37.32903688 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 114487227 114633556 3.12E−05 −24.02221341Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 114834572 1148360470.001802623 −20.99097744 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12114851420 114852038 1.70E−05 −23.75159357 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 114951594 114970093 0.00357488  −23.73801812Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 116075282 1160753430.003327791 −22.05160819 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12117113330 117113548 0.000549237 −24.87894737 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 117523483 117532019 0.006785531 −26.94665072Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 117540303 1175495170.000151874 −26.63814734 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12117662782 117722106 0.001594591 −20.28931931 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 119446615 119447067 1.55E−06 −21.14351852Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 120826946 1208270490.001694183 −34.66823308 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12120848612 120868765 0.004821971 −20.51091236 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 123986856 123986986 0.001694183 −28.88815789Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 124371625 1243717350.000549237 −36.78446115 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12124911808 124912183 0.000103988 −21.54161116 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 124929567 124934247 8.95E−06 −24.69799169Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 124947754 124948357 6.03E−06−51.7127743 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 125028216125028330 0.00328044  −23.0251462 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 125139376 125140409 0.007249297 −22.86453388 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 125189166 125189284 0.001694183 −23.53508772Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 125200272 1252003810.001694183 −36.40953947 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12125577409 125578404 8.97E−08 −34.92924673 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 126094178 126158900 0.004583371 −39.04993355Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 126168496 1261685580.000118163 33.28259109 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12126521536 126628865 0.000496559 −34.44690706 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 127211340 127211472 0.002026583 25.65476771Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 127630580 127630848 1.82E−1238.30059906 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 127940182127940721 3.12E−08 30.57666611 Hyper-methylated NEPC|CRPC-Adeno DMRschr12 128751411 128752217 2.78E−09 22.39471323 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 129337978 129338632 2.61E−13 29.42718585Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 129612373 1296125670.00060921  −24.54083124 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12130388656 130388931 7.00E−06 22.9924925 Hyper-methylated NEPC|CRPC-AdenoDMRs chr12 130646462 130646726 1.14E−08 22.57065902 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr12 130646805 130648788 1.83E−19 24.00415024Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 130823804 130823918 5.79E−0728.16022417 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 131310832131311089 0.000549237 25.83118777 Hyper-methylated NEPC|CRPC-Adeno DMRschr12 131512554 131513385 1.70E−05 −35.57486111 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 132250701 132250808 0.001694183 22.53265107Hyper-methylated NEPC|CRPC-Adeno DMRs chr12 132329721 132330391 1.70E−06−39.02165135 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 132348615132348838 6.82E−05 −23.89653621 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 132353143 132354330 0.005992671 −21.82397661 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 132682540 132682679 0.001012154 −20.12865497Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 132839379 132841040 3.26E−05−25.70280702 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 132853709132854580 1.59E−07 −21.02337363 Hypo-methylated NEPC|CRPC-Adeno DMRschr12 132864172 132865506 3.32E−07 −27.70413012 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 132924815 132928455 0.002976353 −26.17209691Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 132984810 1329848680.009458442 20.42880486 Hyper-methylated NEPC|CRPC-Adeno DMRs chr12133019415 133020031 6.04E−07 −22.36681025 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr12 133030174 133030467 0.00678631  −21.82296651Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 133033080 133033695 2.79E−06−23.69813264 Hypo-methylated NEPC|CRPC-Adeno DMRs chr12 133196600133197669 0.004222625 −32.11548181 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 19174214 19174286 3.15E−05 21.85111111 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 19449235 19449290 1.55E−06 30.05216862Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 20138857 20139255 6.97E−0624.4412594 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 21005474 210063895.50E−05 −25.89185928 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1321573175 21576348 0.002094266 −22.14859248 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 21612297 21623670 0.002976353 −28.34768469Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 23734294 23734636 3.68E−0725.30048733 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 2520111625201530 1.41E−06 24.60307696 Hyper-methylated NEPC|CRPC-Adeno DMRschr13 27060178 27060347 0.001694183 31.96492375 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 27317114 27318547 5.32E−07 24.58965186Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 27557494 275575430.004705671 20.33979532 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1327580677 27580740 0.000828392 −25.84210526 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 28367967 28370672 1.31E−09 22.63522399Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 28493311 284934280.000184724 24.28538012 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1328494772 28495705 8.86E−10 −20.67305701 Hypo-methylated NEPC|CRPC-AdenoDMRs chr13 28498276 28499045 1.04E−17 28.40786447 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 28501137 28503509 8.80E−11 23.22999641Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 28554243 28554680 3.60E−1123.30557585 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 2864695528656288 0.000950523 −23.19245499 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 28673714 28674643 3.10E−14 20.72597171 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 28917208 28922822 0.003932932 −25.79587394Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 29068202 29069838 1.48E−4022.84382376 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 2910666429107311 2.28E−19 43.75214868 Hyper-methylated NEPC|CRPC-Adeno DMRschr13 30535400 30566977 5.50E−05 −21.93820663 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 30690627 30699233 0.000832692 −26.57361111Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 31618127 31618463 0.00060165328.65332817 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 3532459235324683 0.003525992 −28.43684211 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 37248150 37248593 5.08E−10 31.76371541 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 38444116 38444248 3.29E−08 25.15903683Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 39046872 39252420 2.68E−06−31.80664 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 39261198 392613536.88E−08 22.52865079 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1339261730 39262166 7.29E−15 31.19543129 Hyper-methylated NEPC|CRPC-AdenoDMRs chr13 42029810 42029969 0.000101637 −20.85125368 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 43148278 43148911 1.21E−11 32.67904043Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 44838189 44838383 9.60E−05−22.50219298 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 4845940448472939 0.001694183 −21.11230159 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 49792494 49793603 0.002927544 20.71759259 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 49879528 49879786 5.79E−07 −47.96648148Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 58206369 58209192 2.22E−1026.74165096 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 7916971779177838 3.87E−56 36.82503093 Hyper-methylated NEPC|CRPC-Adeno DMRschr13 84091037 84091126 1.60E−06 −20.47744748 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 99111632 99111800 0.009458442 −28.17901688Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 99189658 99189782 0.001694183−26.31666667 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 9921820099220588 0.003525992 −31.26393762 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 99306419 99306550 0.005737741 20.45565302 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 102068323 102068876 2.35E−18 23.01855024Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 102125568 1022379410.000184724 −31.84405458 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13103052567 103052726 8.90E−05 20.08855672 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 107028785 107028904 0.001694183 −25.34522417Hypo-methylated NEPC|CRPC-Adeno DMRs chrl3 107769800 1077699480.005737741 −30.93819444 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13108997521 109059423 0.001012154 −33.07610693 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 109195809 109367547 0.000155805 −24.94345479Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 109500957 1095065460.001549499 −24.42822246 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13109979889 109987005 0.002989545 −41.29739188 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 110697879 110698977 0.001694183 −21.65Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 110709557 1107706420.003063309 38.63523231 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13111138535 111145024 0.00357488  −25.90923765 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 111210039 111210491 4.65E−07 −38.71063037Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 111249550 1112496750.001694183 25.98040936 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13111774082 111774714 0.003327791 −31.41907895 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 112610659 112610674 0.000549237 20.12440476Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 112706777 112710294 6.69E−1431.61632392 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 112756649112761807 1.11E−26 35.92489084 Hyper-methylated NEPC|CRPC-Adeno DMRschr13 112985166 112985628 1.06E−14 20.46701092 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr13 113105783 113105963 0.000164694 −30.03282651Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 113111797 113112291 7.40E−07−26.55601869 Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 113545793113545935 1.70E−05 −41.28986928 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 113637735 113640302 3.82E−08 −35.70398122 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 113661942 113662108 0.000549237 −30.17202381Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 113784451 113784533 5.17E−0625.71339713 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13 113793462113793627 0.007136365 −30.42857143 Hypo-methylated NEPC|CRPC-Adeno DMRschr13 114283062 114285966 0.002239175 −26.43924709 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 114533721 114533836 0.005737741 −25.71208577Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 114558328 1145584960.000549237 29.26369495 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13114638218 114638757 0.00060921  −33.65776 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 114778607 114780382 5.88E−08 −20.71372814Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 114799776 1148003350.000291618 20.71814442 Hyper-methylated NEPC|CRPC-Adeno DMRs chr13114801102 114805226 0.007958919 −21.35909912 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr13 114873407 114875406 9.90E−08 −30.16654483Hypo-methylated NEPC|CRPC-Adeno DMRs chr13 114977017 114977291 1.70E−05−23.27244898 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 1942274819625821 7.81E−09 −33.963918 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1419890076 20670542 3.98E−21 −31.47684869 Hypo-methylated NEPC|CRPC-AdenoDMRs chr14 20684520 20686496 2.91E−05 −42.38163876 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 21193959 21304447 5.45E−06 −31.36505053Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 21486315 21486540 5.50E−05−23.50798292 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 2318910123214654 6.82E−05 −20.18680837 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 23449995 23450432 1.22E−05 −21.63040936 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 23702016 23730289 0.001134201 −22.05509093Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 23828108 23834024 8.78E−05−23.56539627 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 2404627224046600 1.09E−12 −23.19279778 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 24459410 24459549 0.000168572 −28.65345666 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 24506965 24507014 0.001802623 −32.00205415Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 24601571 24601796 5.01E−05−21.0961501 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 25573237 256056610.004750844 −20.61105705 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1436973223 36978196 1.08E−16 27.22566718 Hyper-methylated NEPC|CRPC-AdenoDMRs chr14 42151114 42583081 5.41E−11 20.86843318 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 45804587 45830153 0.000953892 −32.95357327Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 51326366 51326421 0.001694183−40.1462406 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 52535699 525364821.34E−13 23.25635154 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1454417051 54417301 0.001249757 −23.98531514 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 58061599 58323760 8.77E−08 −37.57646973Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 58332141 58333120 6.91E−2223.67245656 Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 6038678860387033 0.000336992 −21.07293233 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 61746805 61747606 8.10E−31 −20.41793687 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 63203242 63248299 0.001012154 23.64328679Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 65068491 650689200.000340762 23.12473684 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1465409311 65409366 0.001694183 −40.64366472 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 73706304 73706454 3.57E−08 25.72165992Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 73717025 737187490.006031403 −21.80247871 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1473736869 73736912 5.01E−05 −41.30811404 Hypo-methylated NEPC|CRPC-AdenoDMRs chr14 74103313 74110894 0.009458442 −28.49255246 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 74218324 74222044 0.005737741 35.12399749Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 74706759 74707668 9.72E−1924.02879328 Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 7482428674832564 1.98E−09 −31.18950231 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 75018880 75019063 0.000488426 23.82943688 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 75389480 75389686 0.000101637 −23.53976608Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 75445246 75447984 6.82E−05−27.10748544 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 7591973475920280 0.000832692 23.29276316 Hyper-methylated NEPC|CRPC-Adeno DMRschr14 76597532 76597987 0.000209051 21.01052632 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 76957095 76957201 0.000176134 −51.01171418Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 77386556 77391489 0.002094266−31.31745152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 8093111980931196 0.001694183 −38.0962963 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 82020400 82213368 9.99E−08 −27.40325879 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 85996157 85999360 3.84E−14 28.49799338Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 90091472 900919760.000832692 −55.34983215 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1490988577 90989764 0.007136365 −25.68016917 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 91270253 91270445 0.000303685 27.05003249Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 93158631 931608890.009285355 −25.14350329 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1493363673 93376490 0.004750844 21.97654922 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 93383345 93383521 0.001694183 −30.40153867Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 93389472 93389558 0.001694183−22.28855472 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 9342346393427368 1.84E−13 −50.5182402 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1493483952 93484010 5.17E−06 −30.01866029 Hypo-methylated NEPC|CRPC-AdenoDMRs chr14 93797948 93797997 0.001802623 20.02354108 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 94291582 94330545 0.000637678 −22.94855521Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 94365235 94369524 0.000488426−21.00266407 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 9439349794394899 0.000185897 −26.94037803 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 94612526 94619722 0.000549237 −23.58270677 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 94735621 94849240 2.61E−07 −24.04845969Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 94953877 95010686 8.02E−06−26.86749761 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 9501160895035504 9.05E−06 −36.07893942 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 95087354 95150519 3.61E−05 −24.01120605 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 95251457 95319202 4.74E−05 −23.0485513Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 95331232 95354277 0.000721524−23.2340081 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 96128330 961284040.000549237 −24.24185464 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1496557302 96558620 0.000291618 −27.14759436 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 98651725 98811064 1.33E−05 −25.14776836Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 99642636 99655632 0.000949885−20.91748119 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 9974058699740613 0.001694183 21.11754386 Hyper-methylated NEPC|CRPC-Adeno DMRschr14 99834140 99848696 0.00198814  −24.71086079 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 100938379 100989443 0.009458442 −50.45715678Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 101058846 1010589870.001012154 27.91649958 Hyper-methylated NEPC|CRPC-Adeno DMRs chr14101158251 101159582 2.04E−06 −42.48606811 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 101363192 101365077 0.008985252 −26.07134503Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 101986125 102012010 3.02E−14−31.22814575 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 102027154102027192 1.70E−05 21.48571429 Hyper-methylated NEPC|CRPC-Adeno DMRschr14 102047819 102050641 1.60E−05 −21.86576859 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 102197703 102226402 0.000549237 −31.16620964Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 102689127 102689423 3.22E−14−34.19484127 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 103010694103011383 5.25E−18 −20.61947808 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 103011438 103011716 8.77E−08 −29.76934343 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 103286673 103289065 0.001600753 21.00131579Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 103550414 103553881 7.31E−13−30.56743224 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 103630505103645543 0.006675101 −22.12105263 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 103655750 103656106 0.000154411 22.65448952 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 103687146 103687320 1.37E−07 27.00731793Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 103698297 1036992230.002094266 −35.21299342 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14104394681 104394954 3.99E−10 20.82502957 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr14 104457910 104499616 0.000176134 −27.06447368Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 104618099 104621193 1.70E−05−30.41296053 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 104624762104627064 3.37E−09 −26.0267441 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 104630051 104636744 5.19E−11 −22.77658337 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 104640074 104643210 2.52E−22 −22.61808763Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 104648223 104649089 6.16E−05−24.67058897 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 104772686104783311 9.40E−08 −22.71488319 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 104825984 104827169 3.46E−09 −31.19064327 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 104857303 104859403 0.000149914 −23.33632055Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 104899135 104901328 3.07E−14−24.2237406 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 105044399105046248 0.000490451 −20.84824561 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 105064538 105065085 0.007136365 −27.51353383 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 105156942 105158328 9.54E−05 28.6494883Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 105181963 105182533 2.91E−0531.55674034 Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 105242373105242617 0.001065261 29.99115524 Hyper-methylated NEPC|CRPC-Adeno DMRschr14 105251468 105251769 0.000667554 −26.99923977 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 105344651 105345191 4.29E−06 −27.78643845Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 105347562 105347964 3.81E−05−54.36160594 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 105362126105362184 0.000176134 −42.43289474 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 105500756 105509377 2.10E−10 −30.16119302 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 105554158 105554991 1.61E−10 −25.11032442Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 105830612 105830650 2.46E−0537.64473982 Hyper-methylated NEPC|CRPC-Adeno DMRs chr14 105961903105962858 0.001012154 23.21804511 Hyper-methylated NEPC|CRPC-Adeno DMRschr14 106038977 106040449 0.000439429 −26.10527692 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 106235583 106241590 3.84E−06 −20.31707182Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 106285172 106304973 1.70E−09−27.52011163 Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 106319346106319731 0.002976353 −31.6772437 Hypo-methylated NEPC|CRPC-Adeno DMRschr14 106367919 106368202 0.00217795  −29.55339783 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr14 106654887 106660659 3.74E−05 −29.76842105Hypo-methylated NEPC|CRPC-Adeno DMRs chr14 106743690 106854924 2.68E−07−26.35797017 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 2005417720142037 0.000716662 −29.29495229 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 20153587 20488015 3.00E−13 −33.13069745 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 22545642 22545700 4.65E−07 20.45515963Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 22547332 22547924 9.54E−05−20.6419711 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 22559825 225819834.65E−07 −40.35538847 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1522803310 22803379 0.001694183 −36.8754386 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 22923774 22927776 0.003327791 −27.63540448Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 23619053 23657320 0.005557404−20.41249606 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 2381059823811532 0.000153872 −31.20089708 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 24048159 24105920 7.21E−06 −28.59838659 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 25450823 25463427 0.000280098 −20.61881073Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 25857969 25905019 0.000414691−24.02490839 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 2592142325926215 1.77E−05 −28.13142028 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 25940387 26036070 8.96E−16 −23.71918589 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 26050274 26081122 0.001545937 −26.97347017Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 26111319 26179895 1.05E−05−28.90601713 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 2623488326251784 0.00020815  −22.43097118 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 27027045 27027136 0.000549237 −25.30886039 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 27112880 27113282 2.48E−10 24.13362298Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 27113411 271135120.004750844 23.22631579 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1527561338 27574056 9.13E−07 −26.70450292 Hypo-methylated NEPC|CRPC-AdenoDMRs chr15 28051002 28051102 0.001694183 46.99587162 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr15 29211632 29211729 1.70E−05 −45.21989471Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 29310304 29310691 0.000100851−33.66814195 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 2967575429684327 0.000581135 −23.40071011 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 31572539 31600650 6.06E−07 −33.2466235 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 31620632 31622531 1.09E−05 −23.3694134Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 32385694 32535167 0.001694183−33.57017544 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 3473823834755823 0.001221669 −23.69793602 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 39305560 39325707 0.001694183 −23.76929825 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 40225618 40225853 0.000711935 −26.66959064Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 40544411 40551526 1.31E−25−25.89625586 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 4121041141211189 5.01E−05 −40.20701754 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 41877483 41877790 1.90E−18 −22.05305712 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 43502885 43503034 0.003327791 −23.08355263Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 45327001 45375094 2.86E−0520.28939628 Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 5240424252404929 3.83E−27 −27.08735695 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 53081377 53081434 0.000277187 20.60436508 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr15 53097585 53097778 3.27E−07 22.72194457Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 55891230 559387210.000667554 −22.54315789 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1558782494 58811992 1.97E−08 −36.81179979 Hypo-methylated NEPC|CRPC-AdenoDMRs chr15 60287193 60288471 4.37E−10 28.36132519 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr15 62358751 62360466 5.66E−21 −25.68828025Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 63334395 63334762 2.22E−20−27.5857457 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 63753498 637537330.0001248  20.09887218 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1565624830 65625248 0.00367696  −24.11645401 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 65647425 65648343 9.42E−16 −29.20798664Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 68098598 68098654 0.000832692−20.20935673 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 6863169168631914 1.77E−05 −21.57573881 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 68869879 68870394 0.000549237 −21.92556647 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 69940620 69957148 0.000381376 −35.303923Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 70519081 70519141 0.001694183−43.38664717 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 7054488070544981 0.000549237 −39.78345865 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 70707823 70708054 1.55E−06 −39.73640351 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 70877436 70877832 8.70E−06 25.30467033Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 74266058 74266110 1.70E−05−33.85336134 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 7444183374441902 0.001694183 43.27807018 Hyper-methylated NEPC|CRPC-Adeno DMRschr15 74521145 74521366 0.00041315  −49.06725146 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 75030067 75051090 2.46E−06 −22.40754655Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 75108425 75108860 6.28E−0720.06581384 Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 7663947676640054 2.79E−12 30.86904226 Hyper-methylated NEPC|CRPC-Adeno DMRschr15 77923797 77924079 4.74E−05 32.41723761 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr15 79059018 79061261 0.001752695 −22.36665438Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 79124278 79126387 1.43E−05−21.36977738 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 8233639382336790 1.44E−11 −31.77841777 Hypo-methylated NEPC|CRPC-Adeno DMRschr15 83261457 83261553 0.000581135 −33.59276316 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 83282560 83282647 0.001694183 −28.54885478Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 83315699 83315950 0.00506093321.51937522 Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 8392423283937882 7.58E−08 −39.568059 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1584370721 84529633 3.84E−07 −28.73719298 Hypo-methylated NEPC|CRPC-AdenoDMRs chr15 84547184 84672718 2.41E−06 −26.36815215 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 86559748 86787108 3.64E−08 −26.47819631Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 89367140 89390571 0.000111918−25.8840331 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 89392808 894307161.20E−07 −21.87970908 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1589445844 89450655 0.004750844 −21.15441077 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 89514733 89542703 0.000826274 −20.704726Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 90006534 90030354 1.30E−0523.13044362 Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 9035758590358061 5.71E−06 22.3002924 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1590543705 90543791 0.001654934 −22.86861598 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 90837626 90844575 0.000586307 −36.8609874Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 93010185 93043015 0.004222625−20.10112702 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 9538800995388666 1.23E−08 21.60776521 Hyper-methylated NEPC|CRPC-Adeno DMRschr15 96876804 96877682 1.75E−09 34.95865466 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr15 99092952 99128171 2.05E−08 −29.02875167Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 99154066 99180015 3.88E−05−22.62285557 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 9919443199194636 1.37E−07 36.07894737 Hyper-methylated NEPC|CRPC-Adeno DMRschr15 99591062 99600352 0.003087144 −23.52566219 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 99663731 99663937 0.001802623 −20.5004386Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 100337390 1003445940.00222033  −28.01097459 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15100354296 100464678 0.002718013 −32.02711362 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 100913597 100914023 1.00E−10 21.22424269Hyper-methylated NEPC|CRPC-Adeno DMRs chr15 101344328 1013850360.00324027  −30.03501114 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15101394913 101398725 0.003113626 −21.4205653 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 101661313 101661447 1.70E−05 −43.03400376Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 101679706 1016799730.000549237 −34.17242511 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15101853489 101910850 4.45E−10 −29.59507128 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 101915318 101921640 0.000176134 −38.94205228Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 101934407 1019361600.008985252 −23.18588369 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15102042975 102073856 1.13E−07 −26.46161405 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr15 102075075 102077597 9.43E−10 −28.97655463Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 102101748 102144660 7.96E−07−30.18178855 Hypo-methylated NEPC|CRPC-Adeno DMRs chr15 102306000102455350 0.002859601 −20.81069143 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 113682 114458 0.000234574 −26.78041705 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 210028 210106 0.001694183 −22.91194653Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 323724 323869 0.00101215420.95155747 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 422112 4222652.46E−05 −39.34084504 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 460250460737 1.15E−08 −27.60960047 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16633967 634126 9.74E−06 −21.85380117 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 661074 661297 0.004025629 −24.08011696 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 668173 671567 2.01E−08 −26.57288788Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 787647 787982 8.67E−0750.80386865 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 818242 8191694.39E−05 −28.70504386 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 832255833018 3.06E−06 −35.73884046 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16853454 855362 2.99E−06 −27.78505613 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 871962 875955 9.14E−05 −21.30733083 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 883655 893016 8.52E−07 −24.15316922Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 902945 903125 3.42E−05−22.41526435 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 924435 9246802.41E−07 −30.63909523 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 963044963184 0.000176134 −27.80701754 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 967902 968683 0.000581135 −24.55774854 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 1029085 1029193 0.009458442 −20.59758772Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1056659 1056952 7.68E−05−24.31265664 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1101872 11047671.42E−06 −28.31447667 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 11126491113198 0.00158762  −20.97651179 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 1163076 1164302 1.29E−06 −22.80018797 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 1164620 1164965 0.008187764 −20.27443609Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1181947 1183556 0.000756112−20.81161759 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1194924 11958951.04E−09 −37.14430289 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 12084671209004 1.02E−13 −31.06076873 Hypo-methylated NEPC|CRPC-Adeno DMRs chr161228797 1228918 0.004583371 −21.10120946 Hypo-methylated NEPC|CRPC-AdenoDMRs chr16 1259194 1259273 9.61E−06 −23.89332958 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 1308022 1308153 0.001156603 −20.94691858Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1315857 1315926 0.000549237−36.50543024 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1341592 13418341.55E−06 −26.26803119 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 14286831428742 0.000176134 23.56798246 Hyper-methylated NEPC|CRPC-Adeno DMRschr16 1475827 1477371 2.64E−09 −43.18631916 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 1576464 1576669 5.50E−05 −22.80563678Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1921898 1922074 2.91E−0725.25402417 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 2004755 20049220.000549237 −32.44204261 Hypo-methylated NEPC|CRPC-Adeno DMRs chr162058089 2058391 0.000303685 23.06993177 Hyper-methylated NEPC|CRPC-AdenoDMRs chr16 2234860 2235549 8.10E−10 −25.52513107 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 2531703 2533950 7.63E−12 −45.71869471Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 2764280 2764394 0.001802623−28.72347536 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 2834976 28376586.58E−16 −20.53630336 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 28651262865452 0.000153872 −45.01432011 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 2880167 2880559 0.000233887 20.70445067 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 2956333 2956585 0.009458442 −20.3079922Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 3003889 3004580 0.009285355−26.71361999 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 3140322 31405364.44E−08 −26.03854333 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 32091573209326 1.83E−09 30.66894087 Hyper-methylated NEPC|CRPC-Adeno DMRs chr163228973 3229177 0.000953892 −27.72235928 Hypo-methylated NEPC|CRPC-AdenoDMRs chr16 4661314 4661453 0.004750844 23.72717508 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 5185993 5235167 0.000156532 −20.86065527Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 11348611 11348698 0.000176134−23.40789474 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 1624429816244586 0.000168572 −27.84398496 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 19113548 19113636 0.000176134 −43.78571429 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 20135805 20291330 0.004652598 −22.89454365Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 20430603 20641568 6.13E−06−28.62763889 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 2094794820960045 0.002976353 −21.75263158 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 22083989 22084058 0.000200845 26.64210526 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 23766378 23766426 2.91E−06 25.06892231Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 23847120 23848168 3.56E−0827.88193139 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 2528218925619765 3.70E−12 −38.05398595 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 27078806 27095468 0.000235983 −26.02061658 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 28333597 28334088 0.001549499 24.41285505Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 28873779 28874345 1.35E−05−21.01022659 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 2930431929304728 5.50E−05 −33.92898914 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 29328183 29328245 0.001694183 −46.77192982 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 29624354 29625174 1.68E−21 −20.03457361Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 29706242 29706608 0.000151874−31.72602719 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 3420883134256502 0.000476227 −21.97900185 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 34258912 34316427 3.43E−06 −22.80407362 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 34379982 34380215 0.005899637 −25.42Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 34407674 34408169 0.000286322−20.70916331 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 3445669334472704 0.001274051 −24.61945698 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 34490099 34561229 0.001012154 −22.50215382 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 34578438 34622419 2.88E−06 −22.03104094Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 34787178 34787394 0.00017613423.33227124 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 4931560449315759 0.000286322 31.0741956 Hyper-methylated NEPC|CRPC-Adeno DMRschr16 49315841 49316610 1.19E−23 29.34917625 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 49317120 49317299 0.000176134 27.53905843Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 49475473 494867020.000194541 −22.7348194 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1649541930 49559604 9.63E−14 −33.78854036 Hypo-methylated NEPC|CRPC-AdenoDMRs chr16 49737799 49749375 8.98E−06 −23.89931517 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 50637405 50647255 5.75E−05 21.7925559Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 51186522 51188707 8.31E−1031.38498452 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 5130503651426357 0.000154411 23.74670232 Hyper-methylated NEPC|CRPC-Adeno DMRschr16 55015881 55021257 0.000194541 −22.14736842 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 55090618 55090848 1.30E−09 44.20583649Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 55358693 55358725 5.50E−0521.97309942 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 5634585856346113 0.000549237 −58.39924812 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 58787856 58868597 0.001552631 −23.50858206 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 65093517 65147114 0.000129108 −23.14791267Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 65157596 65157663 4.24E−0620.87510443 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 6543196965732199 5.88E−09 −25.19268547 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 66091780 66091933 0.001802623 −29.72769722 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 66550312 66556659 0.005737741 26.29181287Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 69348684 693489930.000214284 22.9235589 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1669776044 69776370 0.008985252 28.15278938 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 69999395 69999434 0.001694183 −21.5489418Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 70680625 70680999 0.000549237−56.82587421 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 7071379670715428 2.94E−06 21.51629739 Hyper-methylated NEPC|CRPC-Adeno DMRschr16 70771008 70772688 0.002751359 22.66231048 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 71475581 71475744 4.87E−07 24.95883607Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 71491322 714913910.000549237 20.54511278 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1672821150 72821200 0.001694183 40.92766885 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 72955745 72974666 0.000398142 −24.17671451Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 75034035 75034591 0.001151409−27.43166228 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 7666892476669090 0.000176134 −36.68219246 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 79007120 79007227 0.00040075  −42.07395003 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 79027562 79030799 5.17E−06 −41.74704944Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 80698286 80714829 0.003113626−24.75555556 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8091552980950178 0.000101637 −25.41132898 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 81042069 81042229 0.001065261 −27.52716049 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 81465376 81465542 5.17E−06 −50.40151515Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 81549231 81549956 1.37E−07−34.34547152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8158713081587186 0.000549237 −29.55079365 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 81672526 81672686 0.001065261 22.44953833 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 81685877 81702223 9.02E−06 −45.37774221Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 81739782 81741668 0.001446886−21.12238013 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8266067682660728 0.000176134 24.54775219 Hyper-methylated NEPC|CRPC-Adeno DMRschr16 83765681 83766983 0.001802623 −32.39482038 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 83974425 83975062 1.60E−06 −37.41336032Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 84074769 84077082 6.49E−05−41.20839676 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8419439684204832 3.63E−05 −23.79258686 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 84551016 84553586 0.000700082 −44.61167446 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 84599812 84600052 0.000200845 −35.09385191Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 84609911 84617818 4.65E−07−37.6535152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 84840191 848404681.55E−06 −34.60175439 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1685320513 85320775 2.78E−10 −36.95352416 Hypo-methylated NEPC|CRPC-AdenoDMRs chr16 85337122 85337367 0.001694183 30.11031746 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 85393998 85395781 1.36E−08 −52.11873705Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 85496576 85514744 1.20E−08−33.86475636 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8559614785596236 0.001694183 −60.25536062 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 85627523 85627767 0.001274051 −49.75840213 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 85635743 85636514 0.000113947 −34.14437135Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 85653107 85662013 3.84E−08−29.57493665 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8596669585979154 2.57E−08 −32.05703678 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 86600284 86600932 4.04E−17 27.25250778 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 86601002 86601457 4.56E−09 25.9594233Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 86601587 86601666 1.37E−0724.17940685 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 8660185686601911 0.000118331 25.51816239 Hyper-methylated NEPC|CRPC-Adeno DMRschr16 86602118 86602229 4.24E−06 25.39592471 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 86612819 86612851 0.000176134 21.93407999Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 87524165 87525417 4.73E−08−24.10266637 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8772235387722683 0.000379987 −21.54571736 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 87738833 87739716 0.004216708 −23.28031008 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 87757047 87757111 0.003525992 −35.2417154Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 87840158 87840512 5.99E−05−20.55639098 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8790237387903252 3.41E−20 −20.01363372 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 88017821 88017887 0.000549237 37.3700919 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr16 88053037 88053146 0.001694183 23.75341131Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 88096362 880994470.00010581  20.89598997 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1688134817 88135083 0.009458442 −25.72417154 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 88144486 88161666 4.58E−08 −21.74832719Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 88166151 88169176 0.000324528−22.32145468 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8818411888184820 0.000155879 −26.75048733 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 88228127 88228483 0.00678631  −31.29760766 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 88260875 88266663 1.55E−06 −28.58778643Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 88294661 88316692 7.10E−08−28.4773006 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 88452947 884538170.00013534  −24.52246466 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1688606149 88608168 2.28E−05 −25.05968045 Hypo-methylated NEPC|CRPC-AdenoDMRs chr16 88742761 88743044 0.000176134 −44.55471169 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 88800103 88800909 2.94E−06 −24.70305973Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 88879949 88883094 0.000921835−29.20717513 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8895368288953888 0.001532655 −27.42852792 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 88990394 88992139 9.75E−08 −40.39645216 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 89055721 89055932 1.55E−06 −45.43057644Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 89202582 89202990 2.76E−05−22.65460526 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8922743489229027 0.003484081 −22.30962824 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 89241586 89242638 5.23E−05 −28.61555878 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 89266568 89266808 0.000484821 −26.39107143Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 89651682 89651863 0.000324528−39.53326023 Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 8969764089698943 0.005992671 −23.59464286 Hypo-methylated NEPC|CRPC-Adeno DMRschr16 89764190 89764332 1.77E−05 −38.12559809 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr16 89972593 89972865 6.03E−06 −27.32763158Hypo-methylated NEPC|CRPC-Adeno DMRs chr16 90066682 90068394 0.00169418323.26970551 Hyper-methylated NEPC|CRPC-Adeno DMRs chr16 9014892290148997 0.001715076 −23.85760234 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 155004 155155 0.002094266 −29.52155388 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 216813 216897 1.55E−06 −43.8495614Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 291029 292905 1.87E−09−23.16203008 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 400400 4072610.00040075  −21.76733738 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17707821 708522 2.51E−06 −34.75465418 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 729503 732556 0.000392904 −20.73004948 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 915194 915963 5.69E−17 −43.95834833Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1011493 1011548 0.001694183−21.81810429 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1026731 10277520.000300035 −29.3187794 Hypo-methylated NEPC|CRPC-Adeno DMRs chr171174036 1174134 7.87E−11 22.93517544 Hyper-methylated NEPC|CRPC-AdenoDMRs chr17 1184078 1184313 3.94E−05 −21.50020846 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 1509924 1510019 0.000303685 −27.42280702Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1614142 1618107 0.00075521325.45276316 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 1658766 16593423.15E−05 −38.53315789 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 18198661822567 5.76E−06 −33.77989934 Hypo-methylated NEPC|CRPC-Adeno DMRs chr171861788 1864443 2.01E−06 −37.03054163 Hypo-methylated NEPC|CRPC-AdenoDMRs chr17 2207832 2207954 0.000200845 −33.66180451 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 2262937 2263058 1.30E−06 −28.31117974Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 2278817 2279116 0.00017613420.37469846 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 2806262 28076300.002989545 −20.93184476 Hypo-methylated NEPC|CRPC-Adeno DMRs chr173549305 3549546 1.70E−05 −33.4480805 Hypo-methylated NEPC|CRPC-AdenoDMRs chr17 3588767 3591497 0.001012154 −25.08514142 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 3652671 3652708 0.000953892 −23.96317617Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 3858421 3858592 0.000153872−28.16491228 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 3907313 39075388.34E−06 39.30190058 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 40741014074194 0.000176134 −20.84356725 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 4478978 4479211 0.007673974 −25.8215812 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 4502955 4503992 6.29E−06 −39.48704733Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 5015907 5016031 0.000176134−35.05637792 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 5026278 50335393.73E−10 −23.35926354 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 57406925772485 0.000953892 26.91825397 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 6606244 6610641 0.000286322 −23.66867168 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 7010399 7010665 0.000176134 −52.91644737Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7041409 7043582 0.000200845−37.95918755 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7349953 73504403.04E−05 22.63500223 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 79425037942938 1.35E−09 22.86024436 Hyper-methylated NEPC|CRPC-Adeno DMRs chr178053368 8054763 0.0001438  32.68809841 Hyper-methylated NEPC|CRPC-AdenoDMRs chr17 8702445 8702752 3.09E−12 −27.00337275 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 8931504 8968415 0.00055492  −26.48604524Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 9048263 9054773 1.27E−05−36.22605994 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 9960630 101000031.46E−18 −36.79670646 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1710110814 10220689 4.02E−07 −36.82443504 Hypo-methylated NEPC|CRPC-AdenoDMRs chr17 10230613 10269859 7.07E−07 35.94446794 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 10528325 10528450 0.000953892 −32.56184211Hypo-methylated NEPC|CRPC-Adeno DMRs chrl7 10535221 10559324 0.000392904−24.73589744 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1070673110761061 6.29E−07 −44.01210584 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 10782976 11096605 6.22E−05 −25.59527198 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 11228359 11490071 5.29E−13 −23.84131368Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 11520809 11679161 2.68E−15−28.80589106 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1168764811866643 5.92E−08 −23.26462034 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 12151995 12205432 1.55E−06 −32.83114035 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 12615473 12622349 0.005737741 −28.74147173Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 12650265 12681844 1.82E−05−27.51982878 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1418476214198441 1.70E−05 21.21725146 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 14201910 14202097 6.48E−07 23.07017544 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr17 15164917 15166502 1.94E−06 23.84690894Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 15652986 15653116 1.09E−0823.14568427 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 1584773915847786 0.005737741 21.34015595 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 16373648 16373942 1.55E−06 −41.12807018 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 16908675 16911402 0.005737741 −22.02797619Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 16932252 16933471 0.009458442−27.97642544 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1725892017259771 0.000549237 −34.36915082 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 17345719 17345760 0.001694183 −38.85972222 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 17649212 17652682 5.79E−07 −37.03412281Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 17815463 17815842 0.004750844−26.75044497 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 1802646618026639 0.004906972 −22.08220098 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 18150147 18150579 2.20E−08 −33.40402047 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 18870409 18870875 0.001012154 −27.59022556Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 19282282 19282596 1.22E−07−23.26481051 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 2121402221214072 0.009458442 −23.65877193 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 21241637 21253974 0.000219024 −29.63203671 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 21308403 21320519 1.24E−09 −22.12445853Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 21476839 21477072 0.001694183−29.03220551 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 2156154521561832 0.001229862 −20.61754386 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 21934869 21953670 0.000102266 −25.24649608 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 21953785 21954046 0.000549777 −24.70929027Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 22203643 25282926 7.95E−06−25.59312853 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 2528981625289898 1.17E−08 32.27715121 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 25480583 25480961 0.002976353 −28.22789818 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 26732104 26732177 0.001694183 −20.42631579Hypo-methylated NEPC|CRPC-Adeno DMRs chrl7 27292056 27296952 0.00928535527.38902649 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 2732650727326575 0.001694183 −30.85087719 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 27332339 27332711 2.46E−15 −21.55506386 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 28299554 28299747 2.76E−05 −60.86517028Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 28885977 28886196 0.000153872−24.49707602 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 2988686929888729 2.86E−13 23.65564264 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 30814995 30816457 2.48E−05 −28.88156666 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 31011187 31011254 0.000828392 −26.99342105Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 33324725 33330630 0.00217476721.78997569 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 3377653333776872 2.19E−09 29.03399359 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 34068350 34068658 5.59E−10 −30.16247515 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 35017720 35017946 0.000224358 −35.25577485Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 36286578 36371581 2.46E−05−28.06637989 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 3666614336667137 1.72E−33 −24.4491434 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1736692433 36696116 1.70E−05 −42.31842105 Hypo-methylated NEPC|CRPC-AdenoDMRs chr17 36813715 36817440 0.003063309 −26.951417 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 38769073 38769292 0.004750844 −21.5380117Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 41607883 41608483 1.55E−06−47.48927005 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 4208192042083794 3.91E−24 −22.77831257 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 42733408 42733893 0.003652661 23.54033521 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr17 42734844 42734898 4.74E−05 −20.90951811Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 43037212 43037655 2.70E−0724.53241735 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 4397352943973730 2.64E−09 −23.34772995 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 44836293 44836427 0.005737741 30.19705309 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr17 45501212 45501632 5.65E−10 −22.65046763Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 47075095 47075887 7.01E−0525.53349893 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 4818852448190385 3.70E−06 −24.8640186 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1748596375 48596437 0.001694183 −32.83442982 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 48858799 48858849 0.000176134 24.45476974Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 55371596 55391244 7.16E−05−27.45328897 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 5563253355642757 0.000832692 −29.69913194 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 55970829 56004262 0.000176134 −28.6679605 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 57642658 57642805 0.00357488  20.63512146Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 60217446 60217678 4.74E−05−26.4645933 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 60767466 607675950.001694183 −29.67098301 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1760821673 60827531 0.00222033  −24.91475318 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 61926254 61926882 4.21E−09 27.03917345Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 62291452 622915820.000484821 −24.71947368 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1762359799 62360154 0.000542154 −23.16140351 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 63553578 63554707 0.000549237 31.0786132Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 64383923 643872490.001694183 −20.34307992 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1764724456 64733778 0.003113626 −26.88749816 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 65487278 65487463 5.17E−06 −38.01818182Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 69077025 69077237 0.000176134−37.46184211 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7041611970416320 0.000549237 −39.20300752 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 70417006 70436512 2.03E−05 −27.51271442 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 70657568 70657830 5.17E−06 −28.76519139Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 70785266 70785335 0.000101637−26.20409357 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7126933871269422 0.001694183 −35.15844298 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 71709442 71716007 0.000194541 −40.33795879 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 71743875 71746259 2.91E−06 −49.20547723Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 71898021 71899573 3.56E−05−20.20286669 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7226429872264379 0.003113626 −20.49561404 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 72306141 72306312 1.70E−05 −38.42149958 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 72322190 72336829 2.26E−09 −26.16578621Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 72350558 72350690 0.00095389237.96869195 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 7269114072700930 0.001274051 −24.78561404 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 72945526 72946377 0.00324027  −25.96264108 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 73073323 73073413 0.001694183 −24.91140351Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 73585636 73586234 7.65E−05−22.58378022 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7361231773619220 4.63E−09 −25.56901729 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 73824014 73824138 1.62E−05 −22.74502402 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 73831455 73832137 0.004686715 −24.79876161Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 73904522 73906744 0.002094266−30.17200292 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7391382673914050 7.40E−07 −28.62135363 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 74133918 74133974 1.70E−05 −29.44555556 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 74138282 74138397 0.001545937 −23.20337206Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 74141386 74141672 1.55E−06−40.81096491 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7469678574696845 0.003525992 −24.9122807 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 74965090 74965740 1.81E−11 −28.23060429 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 75106184 75112522 0.001545937 37.01316254Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 75321510 753216140.002976353 21.02773601 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1775525474 75525552 0.007136365 24.95817222 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr17 75544150 75556717 0.001904835 20.2547121Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 75557102 755588560.000101637 −21.87983575 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1775640945 75641329 0.001802623 −22.8037594 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 75692468 75692572 0.000176134 −20.03092105Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 76112799 76113775 2.96E−05−37.15700215 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7626454176265946 0.0001415  −29.49485346 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 76471490 76471694 0.000263673 −29.50263158 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 76673182 76673287 0.000549237 −25.07744361Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 76899098 76899424 0.000549237−33.26137894 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7692611976926612 2.77E−06 −32.79546668 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 76973622 76977745 3.30E−09 −27.54742565 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 77024092 77028305 1.09E−05 29.91227472Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 77102634 77104721 3.94E−07−21.20069618 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7764450577654024 2.44E−05 −31.51285282 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 77688543 77688776 0.000808696 −21.95717593 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 77916790 77916997 4.03E−08 20.96640351Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 78076207 78079672 4.56E−08−41.22212476 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7816939878169650 0.000832692 −33.81315789 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 78321224 78321333 0.009458442 21.23859649 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr17 78395361 78396367 0.000101637 −40.49078947Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 78417869 78417933 1.03E−05−27.27763961 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7843831778447069 0.000117502 −25.85335104 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 78598698 78620197 6.49E−05 −40.54287967 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 78652902 78652975 0.003525992 −41.20272904Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 78736046 78746738 2.76E−05−37.71010955 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7875974978764730 2.50E−06 −30.03933723 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 78819994 78820445 0.000670739 −33.34703302 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 78832469 78833739 0.003808143 −23.88322522Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 78872433 78875062 4.95E−06−27.96011905 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7888273878888279 5.50E−05 −34.47726046 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 78893612 78894478 9.61E−06 −26.53827751 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 79007403 79007879 0.002094266 32.9994152Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 79071073 79071801 2.31E−0521.55921594 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 7921975179219890 0.001608723 −27.23369023 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 79224043 79229561 1.80E−08 −34.36076355 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 79276696 79277025 8.87E−06 −20.83618421Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 79383521 79383993 3.05E−05−35.95336338 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 7938853879390891 1.44E−13 −32.99476877 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 79393653 79394177 0.009285355 −31.57918801 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 79400097 79400753 0.001492528 −29.51705059Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 79532081 79532452 4.24E−0625.87819549 Hyper-methylated NEPC|CRPC-Adeno DMRs chr17 7979949679799525 0.000184724 27.5678525 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 79970290 79971389 2.44E−05 −21.41785714 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 80236905 80237030 0.000200814 −32.95947368Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 80294643 80294804 0.005737741−22.66072125 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 8037275080373728 0.001221669 54.03907686 Hyper-methylated NEPC|CRPC-Adeno DMRschr17 80401424 80401915 1.11E−05 24.13307469 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr17 80454497 80454782 0.000903819 −21.5033029Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 80517975 80518372 4.34E−06−23.41949746 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 8064876380648968 0.002432731 −28.26466165 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 80788028 80788377 1.41E−06 −26.69938443 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr17 80914629 80915867 8.25E−08 −41.06770335Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 80968121 80968398 2.35E−05−29.03596344 Hypo-methylated NEPC|CRPC-Adeno DMRs chr17 8101481081015965 0.001802623 −22.12938596 Hypo-methylated NEPC|CRPC-Adeno DMRschr17 81125962 81126730 1.11E−05 −27.3560307 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 75658 75998 4.82E−06 36.99894344Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 334794 449798 0.001660911−20.74100246 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 4147291 43373893.27E−07 −34.36188494 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 55431595543932 1.16E−23 32.2432484 Hyper-methylated NEPC|CRPC-Adeno DMRs chr185545242 5577549 0.001065261 −28.16790997 Hypo-methylated NEPC|CRPC-AdenoDMRs chr18 5628489 5630725 5.25E−46 31.23235399 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 5890293 5891826 8.90E−46 43.18632076Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 6556270 6634706 1.41E−07−36.4994152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 6797808 69189753.57E−06 −22.01492342 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 70681477115960 2.14E−07 −24.11120635 Hypo-methylated NEPC|CRPC-Adeno DMRs chr187120609 7172357 6.66E−05 −20.69170475 Hypo-methylated NEPC|CRPC-AdenoDMRs chr18 7370850 7371021 5.50E−05 24.72956465 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 7677985 7804451 0.000921835 −21.2020202Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 8394353 8394533 0.001694183−48.30318627 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 8659584 86601128.97E−08 −55.51884122 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 88447688845067 1.70E−05 −43.19979016 Hypo-methylated NEPC|CRPC-Adeno DMRs chr188912451 8935685 0.001065261 −37.41020143 Hypo-methylated NEPC|CRPC-AdenoDMRs chr18 11149243 11149551 2.78E−10 25.70827947 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 11697664 11751264 3.61E−07 −30.46443807Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 11751678 11751841 0.00028632221.92816416 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 1191772311943273 6.65E−05 −26.35537562 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 11994232 12006937 0.000950523 −25.66920795 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 12139501 12236405 8.97E−07 −22.55416741Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 12247455 12247499 0.001694183−34.97354108 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 1316451313164650 0.001694183 −27.58918129 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 13765981 13821981 5.92E−05 −20.73623113 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 14145797 14173352 8.16E−09 −28.74286327Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 14179084 14179364 0.00092668441.99836466 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 1422185114393937 2.23E−18 −31.1325109 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1814431272 14431428 2.18E−08 27.72054411 Hyper-methylated NEPC|CRPC-AdenoDMRs chr18 15197752 15197801 0.001694183 33.80175439 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 15261217 15261271 0.000581135 −31.94736842Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 15329900 18516173 0.000672574−27.39216616 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 1979348519803796 0.007136365 −25.2424812 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 21437853 21437989 0.001012154 −24.88293651 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 22965138 23570664 3.47E−05 −20.70556205Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 23869543 23986382 0.004750844−21.16466165 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 2404372124128145 1.46E−07 38.88147122 Hyper-methylated NEPC|CRPC-Adeno DMRschr18 24301879 24348460 5.50E−05 −41.08638262 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 24598939 24681481 4.65E−07 −43.09462358Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 25117072 25157386 0.000396595−33.17815187 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 2536625825442245 1.17E−08 −49.37024854 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 25545804 25662301 0.009274146 −23.39980269 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 29719797 29723172 0.000908052 −43.04432483Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 30896422 30896504 0.000549237−32.4375 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 31020556 310209167.29E−15 33.2286151 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 3376800433768064 1.70E−05 28.46684211 Hyper-methylated NEPC|CRPC-Adeno DMRschr18 34850803 34866666 3.07E−13 39.61752777 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 35014283 35059155 5.34E−05 24.68867345Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 42324317 42325096 2.55E−13−29.35696572 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 4290158642901643 0.001694183 −39.11783626 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 43732943 43732998 0.001694183 −34.38283208 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 44773018 44774815 3.88E−27 35.39995946Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 44780729 44790503 1.02E−1927.31399674 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 4638630546386822 5.01E−05 −20.09974937 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 47026017 47026653 0.007136365 −21.66766917 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 47812965 47813193 4.65E−07 −24.69747526Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 48637066 48637129 0.00054923726.20841688 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 5192175452019720 0.004750844 −35.99744152 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 52508234 52591105 4.65E−07 −26.07759784 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 53047047 53238004 0.000549237 −33.22742272Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 53269037 53435792 1.71E−10−36.25301297 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 5344747653447803 3.10E−14 33.32333865 Hyper-methylated NEPC|CRPC-Adeno DMRschr18 55469022 55469165 4.95E−05 −20.90794634 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 56259727 56260226 0.001065261 −28.10994152Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 56934972 56935515 0.00021889927.72535088 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 5694084256941558 1.31E−09 28.36486693 Hyper-methylated NEPC|CRPC-Adeno DMRschr18 57106203 57357805 3.23E−06 −34.68633501 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 57363762 57364650 1.76E−25 40.22391517Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 57366036 57556747 1.01E−07−30.65155964 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 5764068857677912 0.000152004 −24.32308222 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 59001049 59001824 3.09E−08 20.67838477 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 60263503 60263750 2.01E−08 30.16628242Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 67069032 67069553 7.87E−1127.32008772 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 6713673367136880 0.000324528 −20.78318713 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 67972299 67972368 0.009458442 21.12631579 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 68166726 68166932 7.41E−07 −55.29662309Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 70536311 70536519 7.87E−1134.41356381 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 7161087771611303 0.003113626 −24.34640523 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 72153858 72153991 1.55E−06 −41.42650785 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 72960958 72961205 1.70E−05 −34.94250774Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 73167240 73168223 2.74E−1436.76761988 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 7362823973628323 8.97E−08 32.73611807 Hyper-methylated NEPC|CRPC-Adeno DMRschr18 74103815 74107798 0.001883547 −25.66330666 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 74754672 74754750 0.001694183 −44.22368421Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 74805178 74805233 0.000176134−57.8546627 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 74961918 749622212.65E−10 31.43779694 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1874962315 74964223 1.69E−15 33.30443051 Hyper-methylated NEPC|CRPC-AdenoDMRs chr18 76069561 76069618 3.18E−06 27.39018843 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 76694294 76695037 0.001694183 −36.48888889Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 77147768 77147847 0.000711935−31.27134503 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 7724483677245030 1.68E−07 −21.14505582 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 77290965 77291471 3.80E−05 −25.71487921 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 77313296 77316500 1.75E−06 −29.56169959Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 77320467 77325890 1.65E−08−43.11216158 Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 7737270477373764 2.37E−06 −24.37929997 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 77512369 77512452 0.001694183 23.98040936 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr18 77534899 77538503 0.000601653 −25.78905597Hypo-methylated NEPC|CRPC-Adeno DMRs chr18 77547894 77548089 4.65E−0726.78505247 Hyper-methylated NEPC|CRPC-Adeno DMRs chr18 7755706377557318 9.09E−05 −29.81704261 Hypo-methylated NEPC|CRPC-Adeno DMRschr18 77607722 77608332 0.005737741 −44.14912281 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr18 77627555 77632025 1.15E−05 −23.34253057Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 397436 397602 0.000549237−31.90412305 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 426998 4271021.70E−05 −27.41677527 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 489778493649 9.70E−06 20.65651084 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19524073 525378 3.90E−06 −23.64102792 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 591312 592180 6.98E−11 44.34577647 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 609127 609421 0.001455962 −23.45263158Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 629784 630015 0.000291618−29.93349282 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 658494 6620416.12E−06 23.05631866 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 740537740726 5.50E−05 −31.11140167 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19855570 855794 4.47E−05 −23.57004548 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 870959 871390 4.55E−09 −34.75051877 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 883736 884368 9.23E−10 −44.98650953Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 898790 898951 0.005737741−22.13253589 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 900754 9010440.000102266 22.0454363 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19903325 903540 4.01E−05 −32.55983276 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 951603 954079 0.007271222 25.6958751 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 1041762 1042088 5.92E−05 −23.26772982Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1064147 1064410 4.24E−06−28.16687552 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1106628 11080210.002023529 20.64123735 Hyper-methylated NEPC|CRPC-Adeno DMRs chr191241167 1241327 0.009458442 −24.53534572 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 1292106 1292610 0.000381376 −21.70368282 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 1340494 1342761 5.17E−06 −31.29391555Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1371048 1371087 5.50E−05−45.9707672 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1397431 13977390.000341437 −20.44259614 Hypo-methylated NEPC|CRPC-Adeno DMRs chr191505824 1506160 0.003503755 −22.34851565 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 1508528 1511932 5.57E−07 −24.11860288 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 1520397 1520541 0.001694183 −48.78637771Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1572254 1574585 0.000700082−24.26105795 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1578712 15788320.001694183 −30.42807018 Hypo-methylated NEPC|CRPC-Adeno DMRs chr191691231 1698714 0.002602569 −21.43010379 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 1719324 1719371 0.007136365 −24.10827068 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 1729494 1734544 1.09E−05 −22.84239881Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1736641 1739365 0.000377187−22.94623206 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1775452 17755250.008187764 20.59449448 Hyper-methylated NEPC|CRPC-Adeno DMRs chr191777638 1787193 6.79E−05 −24.23056121 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 1826552 1826882 0.001694183 27.90158024 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 2016311 2016515 0.000703636 −24.27866411Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2170644 2171709 0.000291618−45.5170938 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2213253 22134050.007136365 −20.2569856 Hypo-methylated NEPC|CRPC-Adeno DMRs chr192255463 2257226 0.00039263  −30.38435673 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 2268262 2268398 0.001802623 24.13082707 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 2299060 2299392 0.000549237 −54.95621196Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2324328 2324440 0.001549499−21.99770259 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2513031 25133036.45E−06 −25.6202879 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 25185092518637 0.00158762  −29.37854251 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 2525152 2525272 9.61E−06 −20.60388756 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 2634461 2635112 3.22E−05 −29.63523392Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2645923 2664817 8.45E−07−23.25229757 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2867352 28674921.37E−07 −28.72671261 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 28891712892153 0.000889013 −20.6314198 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 3046352 3046594 0.001274051 −27.18400376 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 3053360 3053625 0.000263673 −25.58976035Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3195923 3196751 1.69E−08−27.85969346 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3197038 31971770.002376793 −26.63206445 Hypo-methylated NEPC|CRPC-Adeno DMRs chr193220170 3221345 0.000908052 −31.26391452 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 3290504 3293654 0.001904835 −21.6261412 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 3367729 3374005 9.06E−10 20.2080845Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 3398658 3398810 0.00046728830.07544839 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 3571951 35720190.00222033  −26.78684211 Hypo-methylated NEPC|CRPC-Adeno DMRs chr193644460 3645475 0.003652661 20.18509503 Hyper-methylated NEPC|CRPC-AdenoDMRs chr19 3775063 3783899 7.65E−06 −21.10231755 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 3784322 3784436 0.000549237 −23.7481203Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3820198 3821432 2.04E−10−27.78390977 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3823603 38257684.74E−07 −25.81743421 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 38556283860997 0.000711935 −22.40219298 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 3937200 3938364 1.74E−05 −20.9674843 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 4038720 4038745 0.000549237 −24.40037594Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4199744 4204316 0.00064342 −20.48685013 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4233060 42377150.000549237 −24.74043044 Hypo-methylated NEPC|CRPC-Adeno DMRs chr194454848 4455414 0.009458442 22.6226817 Hyper-methylated NEPC|CRPC-AdenoDMRs chr19 4534974 4535447 5.49E−12 −26.78065986 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 4538425 4538648 1.70E−05 −39.23458855Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4566605 4566669 1.55E−06−60.58903509 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4571662 45761170.004786604 −20.51624083 Hypo-methylated NEPC|CRPC-Adeno DMRs chr194846604 4852146 8.71E−05 −28.89836814 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 4977546 4984579 3.38E−08 −31.1306942 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 5035477 5038531 1.71E−10 −31.90807804Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5141239 5141793 5.10E−0820.99015992 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 5307844 53079700.001694183 23.51666667 Hyper-methylated NEPC|CRPC-Adeno DMRs chr195517955 5523949 0.001274051 −22.38698658 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 5727063 5760498 2.64E−05 −20.03420297 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 5781208 5782328 0.000773732 −30.07746289Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5829066 5829466 9.12E−11−22.73137879 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5956737 59641760.008985252 −24.66587977 Hypo-methylated NEPC|CRPC-Adeno DMRs chr196249480 6259748 0.00064342  22.47845201 Hyper-methylated NEPC|CRPC-AdenoDMRs chr19 6284188 6311271 4.38E−06 −20.64282176 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 6501345 6501464 0.000184724 −36.68031189Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 6591008 6591117 0.00557426420.09617225 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 6592081 66312070.000386347 −21.22205115 Hypo-methylated NEPC|CRPC-Adeno DMRs chr197754225 7755302 1.14E−05 −20.37647232 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 7854154 7855656 0.004735829 −22.81671057 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 7934532 7937819 1.50E−12 20.10092043Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 7982226 7982768 3.13E−10−31.71591758 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 7991360 79920464.34E−06 −41.16698233 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 81741558186255 2.54E−06 −24.94782158 Hypo-methylated NEPC|CRPC-Adeno DMRs chr198273471 8273717 0.005899637 20.95734778 Hyper-methylated NEPC|CRPC-AdenoDMRs chr19 8595471 8625294 8.16E−08 −26.5658489 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 9164807 9186967 1.82E−07 −27.62189995Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 9473272 9473869 1.56E−0526.21847536 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 9819060 98476970.000114041 −25.02371804 Hypo-methylated NEPC|CRPC-Adeno DMRs chr199992040 9996397 2.14E−05 −51.33445419 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 10124042 10124310 9.81E−05 −22.89555199 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 10142060 10194578 1.45E−07 −24.21652772Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 10475546 10475642 0.00016857225.91861598 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 1074708310747203 0.002976353 41.37141278 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 11002954 11003232 3.45E−06 −32.59229184 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 11034997 11036416 0.008985252 21.92821637Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 11086500 110908610.009458442 23.34473684 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1911113739 11113942 0.000549237 21.48270677 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 12758753 12759531 1.27E−07 −30.11934089Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 13293066 13293140 0.00169418337.1877193 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 13928585 139291211.50E−06 −26.49755762 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1914043706 14044198 1.25E−15 −41.84347648 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 14094260 14095280 0.000711935 −36.1302794 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 14321876 14323164 0.001545937 −23.16221108Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 14376207 14391911 4.77E−06−23.18042441 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1454290914543000 0.000200814 21.42210526 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 15066284 15083780 0.000549237 −34.93791771 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 15219923 15221487 3.99E−18 −26.88039503Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 15271918 15272337 3.84E−06−28.78340643 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1531053115310570 0.000176134 23.06138393 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 15926482 15939342 0.000711935 −30.32028219 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 15956576 16010462 1.00E−07 −26.48761912Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 16090684 16178030 1.29E−12−26.1360614 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 16221519 162216430.00222033  25.01343985 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1917012756 17068587 9.30E−08 −23.43599941 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 17152290 17152703 0.007136365 −29.3191889 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 17224465 17225643 0.008600948 25.63125975Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 17320350 173205610.000324528 26.46392974 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1917346089 17347033 1.63E−29 22.3191432 Hyper-methylated NEPC|CRPC-AdenoDMRs chr19 17397263 17397679 0.000176134 −26.43925439 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 17438101 17438549 2.00E−06 −26.23284302Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 17476882 17484998 0.000549237−29.94181287 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 1776708217791361 2.70E−09 42.00301353 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 18065301 18076654 0.000934755 −24.50326018 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 18211820 18213958 0.001802623 −21.7943609Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 18267723 18268799 2.52E−06−26.3456126 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 18468371 184798750.000926684 −26.7100731 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1918549549 18549735 0.000184724 24.71721897 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 18706030 18706289 0.000247501 24.763055Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 18836691 188371070.000549237 −69.08478488 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1918867715 18868406 0.006890179 −27.9128655 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 18872000 18872158 0.007136365 21.33221596Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 19002328 190053360.000313698 −25.2620313 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1919215770 19216380 5.17E−06 −37.44047284 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 19252221 19252284 0.002094266 −30.58414555 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 19349980 19360041 0.005813728 −21.91089486Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 22611431 22611590 0.00643661 25.75356037 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 2278433922799262 0.000542154 −21.31765019 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 22805745 22805846 0.000184724 31.28219623 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 22966950 22967166 5.75E−05 21.36034056Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 22978007 22989337 5.75E−05−28.93334795 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 2299018022990407 1.51E−06 26.07800701 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 22990489 22990603 0.000542154 20.06485912 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 23457611 23457661 0.001694183 −29.57105263Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 29218495 29218628 0.00011833120.92792237 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 2928440629284930 2.72E−15 24.10907843 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 30109437 30135653 0.007136365 −25.17133807 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 30157793 30158044 0.006890179 20.63926155Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 30339563 303471960.000124569 −22.10334394 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1930647757 30701295 0.000246327 −24.59190846 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 31111162 31142115 3.29E−08 −26.99659526Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 31217434 31226491 0.000392904−21.23995396 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3123144431237122 0.000716662 −22.9479023 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 31411329 31450495 4.74E−05 −25.87915622 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 31601388 31619444 0.001068403 −30.9933845Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 31637152 31640642 2.14E−05−34.25915524 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3175602031762384 4.74E−05 −29.73146408 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 31767694 31800060 7.82E−14 −24.8998062 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 31993850 32008021 0.000835118 −22.29225699Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 32008765 32161906 4.14E−08−26.13246345 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3220993532223877 0.005737741 −25.28191335 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 32260602 32331169 1.71E−06 −24.31292599 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 32627954 32711693 0.001694183 −25.60495808Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 33730345 33731533 0.005737741−33.96332498 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3388326933884683 8.19E−07 −30.14740175 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 34002335 34002501 0.001549499 −20.19802632 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 34175117 34175234 0.000549237 27.03550543Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 34181558 341816380.000549237 −44.01879699 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1934318594 34394363 6.16E−05 −22.55477808 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 34400312 34531867 1.11E−07 −28.64637005 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 35793438 35793520 0.001694183 −35.21929825Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 36246395 36246790 8.73E−19−26.62591383 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3631926036319819 8.09E−05 40.45263158 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 36450599 36451091 9.76E−10 −26.8624496 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 36749224 36750486 0.001310325 −20.3417401Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 37795602 37795949 0.007673974−22.25140453 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3804213838042382 6.16E−14 36.36973328 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 38345759 38346574 2.08E−05 26.977811 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 38527889 38528133 5.50E−05 −56.31360318Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 38684237 38684378 0.000100851−58.43795853 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3885111138851294 0.002976353 −29.48399921 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 38901735 38912074 0.00013882  −22.71328772 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 39011057 39017921 0.000337166 −28.62690941Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 39034510 39053147 0.001963239−25.42822368 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3915375939167310 5.84E−05 −26.69099415 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 39193073 39193195 0.004750844 −40.32840557 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 39369103 39369432 0.003327791 −29.89029605Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 39384074 39384230 1.55E−06−31.79936647 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3954072839572391 0.001549499 −23.83892988 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 39593570 39613396 8.38E−05 −21.01802036 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 39672281 39672432 0.004750844 −26.09974937Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 39738370 39738859 3.07E−11−21.84315869 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 3999341539994863 3.72E−12 32.2470451 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1940344146 40362928 0.006675101 −30.93596491 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 40889863 40890001 5.50E−05 −24.5374269Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 41116313 41116527 1.50E−0621.67120743 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 4111703741117285 1.35E−06 −27.25065906 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 41129575 41130048 0.001274051 −31.74226608 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 41370990 41431809 0.003932932 −21.17071034Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 41494546 41571481 0.000667554−23.14338837 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4170035841703652 0.000522011 −24.47348887 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 42056914 42056948 0.001694183 −28.45438596 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 42436728 42437375 9.61E−06 −23.59174641Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 42618590 42618828 0.000549237−45.10927318 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4420370544203953 1.54E−10 24.20912281 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 44287281 44287377 0.001694183 −24.68703376 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 45198545 45200817 7.42E−07 −29.69058845Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 45633604 45633814 9.09E−05−28.81159844 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4564074745640980 7.96E−07 −32.29637605 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 45992528 45996499 0.000721524 35.4560054 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 46285560 46285769 0.000209051 −27.23157895Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 46404991 46405120 5.34E−09−20.14210526 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4720091947201289 0.000832692 39.54809942 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 47823993 47827068 0.000280041 −25.39675009 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 47844645 47845538 0.000549237 −20.19506911Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 47960175 47960422 3.80E−0521.18215358 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 4828532248285464 0.001694183 30.73684211 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 48355335 48379983 2.23E−08 −25.56577676 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 48699556 48699873 1.50E−06 −50.95697454Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 48945846 48946375 3.33E−1522.94866575 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 4900061249001068 6.76E−12 −24.41349538 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 49183866 49183927 8.67E−06 −22.45883442 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 49265604 49272230 0.005737741 −22.48480861Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 49368815 49373087 0.006785531−20.66804642 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 4937881749386050 5.50E−06 22.54897661 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 49724230 49756344 0.000381376 −20.85091983 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 50002809 50003695 0.007379618 22.2691416Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 50139374 501404260.001197874 −24.31226741 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1950204667 50204770 0.001003946 20.24880383 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 50563540 50580135 2.68E−05 −27.21026316Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 50691267 50693648 1.94E−06−25.07041562 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5091813250918386 8.35E−06 24.5462406 Hyper-methylated NEPC|CRPC-Adeno DMRs chr1950962555 50967852 0.000721524 −21.68663968 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 50969644 50969782 5.50E−05 −37.0754386Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 51055609 51058607 5.61E−05−27.65397685 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5107231251106013 0.000476559 −27.03668854 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 51124272 51130909 0.006890179 −29.38583496 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 51133255 51141334 0.00217795  −31.64432011Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 51144628 51156592 0.002174767−33.41510592 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5116551351165602 0.002976353 −29.25927318 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 51165693 51165766 0.001642117 −27.64736842 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 51171271 51171370 3.81E−05 23.05668016Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 51171495 51171543 5.17E−0631.94743488 Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 5119184551192276 2.76E−05 −29.20917679 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 51199254 51207051 3.38E−08 −23.14664099 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 51446863 51487774 3.59E−09 −29.89163673Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 51519143 51519187 0.001694183−21.21491228 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5161549751640963 1.55E−07 −36.34136444 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 51844485 51844808 1.40E−06 −23.91701389 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 51873185 51892512 5.89E−07 −24.89514772Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 52206187 52206908 2.64E−09−26.15069215 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5222292552222993 0.005737741 21.71403509 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 52223076 52223159 9.54E−05 26.38338493 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 53966535 53966883 1.85E−07 −20.01984279Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 54101736 54126874 0.000282282−24.1482509 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 54255090 542661592.16E−05 −27.51664759 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1954291217 54337321 1.10E−10 −23.47392545 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 54445326 54445403 0.001770881 20.94207086 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr19 54466570 54466618 1.74E−05 21.478467Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 54466703 544685860.004705671 −20.87972222 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1954524742 54565132 3.34E−06 −34.04258484 Hypo-methylated NEPC|CRPC-AdenoDMRs chr19 54568176 54598906 5.53E−05 −24.29076566 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 54926424 54926522 1.72E−06 23.6535731Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 54982501 54987554 7.38E−13−20.41216517 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5548834555510533 1.84E−09 −24.65547492 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 55602709 55602837 0.000926684 −29.91357143 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 55870268 55871136 5.76E−07 −41.11788166Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 55944512 55948471 1.22E−11−20.09759004 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5597581255978467 0.000113947 −20.7416423 Hypo-methylated NEPC|CRPC-Adeno DMRschr19 56061320 56066470 7.36E−05 −32.59598301 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 56215437 56215478 0.001694183 20.8489418Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 56292510 563083510.001291252 −21.05508215 Hypo-methylated NEPC|CRPC-Adeno DMRs chr1956724715 56728063 0.000889013 −33.21359649 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 57182985 57183206 1.47E−06 27.41616905Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 57293485 57335932 8.60E−08−23.58802577 Hypo-methylated NEPC|CRPC-Adeno DMRs chr19 5761824357618297 0.000439429 27.90736842 Hyper-methylated NEPC|CRPC-Adeno DMRschr19 58571236 58571389 0.003348504 −23.43580247 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr19 58629408 58629979 7.27E−07 24.03635709Hyper-methylated NEPC|CRPC-Adeno DMRs chr19 59027797 590279080.004750844 20.82406015 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20308963 309137 0.001197874 24.49033189 Hyper-methylated NEPC|CRPC-AdenoDMRs chr20 644060 644131 0.004280014 21.59537037 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr20 892978 922263 0.003327791 −25.5375Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 941014 978552 7.73E−06−23.42119816 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 982700 9830224.48E−08 21.1380332 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 10086361036633 0.005239183 −21.26397967 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 1813231 1838648 0.000118331 −22.70699902 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 1874385 1874528 0.000200845 24.53833333Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 1950637 1978368 2.14E−05−28.77314241 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 2384312 23979270.002766856 −24.13716678 Hypo-methylated NEPC|CRPC-Adeno DMRs chr202739596 2740810 0.000667554 −27.50697368 Hypo-methylated NEPC|CRPC-AdenoDMRs chr20 3149092 3149321 0.000926684 −20.53947368 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 3635436 3635682 0.00041315  −41.81193384Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 3728978 3730912 0.004665474−22.9276477 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 3777367 37815314.69E−08 −41.84571589 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 47054074764803 0.005772821 −21.50853523 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 4804547 4804841 0.002859601 27.80504939 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr20 4836335 4836367 0.001694183 35.55588235Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 5297352 5297976 1.12E−1023.01575592 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 5594626 55948360.004750844 24.15910856 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2010152802 10152959 8.81E−05 −20.56667236 Hypo-methylated NEPC|CRPC-AdenoDMRs chr20 10198822 10200166 1.45E−05 −20.75366357 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 10249807 10304164 3.15E−05 20.77105828Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 10774468 10776151 2.46E−05−25.4325188 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 19192410 191925080.004750844 −20.06541353 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2019804533 19804617 5.17E−06 −21.57511962 Hypo-methylated NEPC|CRPC-AdenoDMRs chr20 20180690 20232393 6.29E−06 −44.08042265 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 22549081 22549680 4.86E−11 26.5121258Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 22699929 227439190.002226263 −24.40757009 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2023088974 23098317 7.00E−05 −20.21149085 Hypo-methylated NEPC|CRPC-AdenoDMRs chr20 23481003 23601812 0.000446011 −29.65163711 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 25062860 25065114 3.57E−12 23.11482902Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 29519510 295196380.006785531 −29.75972222 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2030432637 30433410 1.28E−08 30.82253245 Hyper-methylated NEPC|CRPC-AdenoDMRs chr20 31052241 31053634 0.000263232 22.60240416 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr20 31129334 31129483 0.00041315  −48.31754386Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 31211535 31216161 0.000229476−21.30189899 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 3205368932064711 0.001694183 −33.19298246 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 33880930 33884334 0.005098191 −23.04328599 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 34004828 34009635 0.001545937 −20.35347628Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 34978025 34978408 0.000153872−23.79789474 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 3501230235012357 0.009458442 31.51998051 Hyper-methylated NEPC|CRPC-Adeno DMRschr20 35441156 35441225 0.001694183 20.3075188 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr20 36226619 36226659 0.000549237 −25.53071518Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 36496319 36496400 0.00545664521.05943627 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 3692335436924055 0.000488426 −51.75361552 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 36964033 36978049 3.26E−06 −26.39951023 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 37303221 37303650 3.09E−06 23.33381144Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 37356911 37357223 7.13E−0925.31559454 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 4253297642533173 0.001065261 −28.29167527 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 43027683 43035902 2.55E−05 −24.07334482 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 44659599 44659671 0.000549237 25.46491228Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 44803094 448032900.000100851 24.13308271 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2045946166 45946318 0.001694183 −23.05701754 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 48099278 48099484 8.73E−10 51.8393322Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 48626444 48626687 1.02E−0820.63158755 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 4895901948959154 0.000549237 −40.03773773 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 48995552 48996022 0.005574264 −36.97501329 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 49591789 49597361 0.003113626 −34.26578947Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 49626842 49632122 0.000246327−26.41781377 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 4965689749749183 0.004215557 −20.75067202 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 49774918 49810369 9.90E−06 −26.66495666 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 50045047 50045181 0.003327791 26.32434211Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 50827403 51273043 9.98E−11−28.53140485 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 5229367352314356 6.62E−09 −20.39072134 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 52870107 53068788 9.35E−05 −26.63391712 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 53092153 53092934 3.40E−19 28.83178016Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 55019425 55032395 1.42E−06−21.40840613 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 5511036955188960 1.54E−06 −22.64041436 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 55196326 55199018 0.000581135 −25.99456976 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 55291980 55373228 4.10E−17 −34.89760506Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 55378475 55486484 1.81E−08−31.52491816 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 5550375355580949 2.24E−09 −35.74186142 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 55595661 55622875 3.54E−05 −30.7472897 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 55700894 55838701 8.73E−24 −27.2291685Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 55849101 55924338 5.31E−08−29.56591269 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 5614355256145310 0.003113626 −30.29561404 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 56160313 56167924 0.000185101 −23.22577634 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 56706312 56711095 0.000549237 −26.90902256Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 56725858 56725950 5.01E−05−25.8872807 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 57267427 572676770.000749344 26.13758822 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2057291744 57292353 0.000342136 −38.74633279 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 57370578 57376122 8.71E−07 −29.69945878Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 57382431 57397852 1.35E−06−22.96008553 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 5742843757429026 0.001310325 −24.24502924 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 57504269 57520234 0.003932932 −36.35698506 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 57875645 57875752 9.81E−05 22.56408283Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 60509158 60509203 4.34E−06−22.0242915 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 60580224 605813330.002976353 24.47092732 Hyper-methylated NEPC|CRPC-Adeno DMRs chr2060966906 60967143 1.94E−06 −24.07206497 Hypo-methylated NEPC|CRPC-AdenoDMRs chr20 60986425 60987132 0.000128281 −30.5644615 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 61024219 61024433 0.00060921  −24.59098441Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 61028387 61033505 3.10E−08−21.25774926 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 6104102561043756 3.41E−09 −20.40288438 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 61143412 61144016 0.000337664 −24.82181287 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 61458886 61459302 4.69E−05 −26.69353744Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 61703436 61703547 0.00044391626.144843 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 61877855 618785250.000244357 −25.95076401 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2061886650 61887454 1.15E−05 −34.24235589 Hypo-methylated NEPC|CRPC-AdenoDMRs chr20 61891462 61900000 8.07E−05 −21.82449216 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 61947110 61959889 5.94E−14 −25.31844096Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 61998337 61999044 0.001274051−29.32428571 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 6203753962037702 0.004750844 −26.71613025 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 62056252 62059360 4.25E−11 −23.16045884 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 62069526 62069958 1.70E−05 −27.48578947Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 62097963 62098052 0.000953892−24.30838816 Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 6213358262134468 0.003890964 −24.77323099 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 62158446 62160647 0.009285355 −23.3651302 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr20 62181232 62181658 0.000151874 −22.99764753Hypo-methylated NEPC|CRPC-Adeno DMRs chr20 61499167 62499360 0.00678553123.60222039 Hyper-methylated NEPC|CRPC-Adeno DMRs chr20 6167951462680150 2.58E−23 −27.75461559 Hypo-methylated NEPC|CRPC-Adeno DMRschr20 61700743 62700795 0.001545937 −22.1571475 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 9476854 9476919 0.001694183 −34.22894737Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 10137563 10428163 0.002551933−27.80873968 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 1507757515077588 0.001694183 22.94696405 Hyper-methylated NEPC|CRPC-Adeno DMRschr21 15095805 15095832 0.000176134 28.39940476 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr21 15426939 15430513 0.000549237 −26.94847413Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 15443388 15448272 1.92E−17−20.43753804 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 1544979715459405 6.19E−08 −22.49249196 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 18985383 18985669 0.000187922 21.74845483 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr21 19252484 19371261 4.10E−05 −22.0295447Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 16934465 26934515 0.00169418329.44159111 Hyper-methylated NEPC|CRPC-Adeno DMRs chr21 1910917829254156 0.003113626 −38.16666667 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 19157879 29636388 2.48E−08 −25.47914469 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 19981165 30110926 4.66E−05 −28.95317982Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 34399314 34399361 0.00073298322.31244019 Hyper-methylated NEPC|CRPC-Adeno DMRs chr21 3448411134487710 0.005737741 −20.57017544 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 37816185 37832557 0.006785531 −23.97017544 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 38638311 38638380 0.003525992 −28.70438596Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 38913493 38935585 0.000414691−32.20423787 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4003131140032680 3.18E−22 33.99714482 Hyper-methylated NEPC|CRPC-Adeno DMRschr21 41853755 41853981 0.009458442 −23.75877193 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 41798037 42798287 1.54E−10 −25.27894737Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 41880155 42880727 9.24E−0629.09683402 Hyper-methylated NEPC|CRPC-Adeno DMRs chr21 4314379143256688 1.07E−13 −27.99569484 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 43441865 43442438 2.14E−05 −42.22581126 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 43491949 43493461 0.006890179 −35.41474984Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 43714205 43714346 0.003327791−21.10710892 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4380973543816264 0.001694183 −22.40031605 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 43979021 43982996 1.55E−07 −22.93004369 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 44098158 44098331 0.000549237 −35.28571429Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 44561049 44562122 1.98E−05−34.22793522 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 4459850144599091 0.001694183 −29.78235867 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 44784605 44784739 0.000176134 −28.78267544 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 44787356 44787478 5.50E−05 −28.21118755Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 44836765 44837407 1.74E−08−43.07905314 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 4485030144851787 2.92E−06 −42.27993135 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 44871416 44872479 1.71E−10 −34.52655229 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr11 45340509 45341350 0.000721524 −21.29966262Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 45356201 45356341 0.000100851−34.05113636 Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 4541139445413046 5.70E−08 −22.75322858 Hypo-methylated NEPC|CRPC-Adeno DMRschr11 45590916 45591002 0.000549237 24.87848438 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr11 45653978 45654420 5.01E−05 −49.06045142Hypo-methylated NEPC|CRPC-Adeno DMRs chr11 45698914 45699784 0.000100851−51.81913876 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4570403045706080 6.32E−13 24.51650599 Hyper-methylated NEPC|CRPC-Adeno DMRschr21 45770551 45770639 0.000118331 23.39190283 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr21 45845119 45852821 1.67E−07 −21.37780214Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 45881843 45887854 7.38E−10−26.89365863 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4593349145933891 0.000921835 −36.82032164 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 46107858 46107921 0.000549237 −24.79924812 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 46157160 46265028 0.000538714 −20.94494285Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 46306516 46308476 1.35E−06−29.01161062 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4632331546330303 3.17E−06 −22.03156502 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 46336367 46338310 0.000667554 −42.5700731 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 46353573 46353966 4.69E−06 −31.03906433Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 46404548 46406951 1.98E−06−20.77381971 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4640998146410237 5.75E−05 −32.99108396 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 46412189 46420543 4.08E−08 −30.80796682 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 46421390 46422950 0.000324528 −24.85Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 46431972 46436249 2.71E−05−23.58437152 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4658156446581767 0.001694183 −21.09649123 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 46677446 46678543 2.78E−13 −28.46010592 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 46777787 46778116 0.00302923  −24.71052632Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 46876301 46888880 1.47E−30−27.53908993 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4693576146936040 0.000291618 27.58175876 Hyper-methylated NEPC|CRPC-Adeno DMRschr21 47009971 47010272 1.95E−10 24.70583256 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr21 47035536 47035697 0.001694183 −24.1204793Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 47295095 47295140 1.70E−0520.46214986 Hyper-methylated NEPC|CRPC-Adeno DMRs chr21 4739274147392981 1.78E−06 −21.68457254 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 47405532 47409042 4.87E−07 −20.7702046 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr21 47421891 47423680 1.14E−11 −22.47693381Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 47423918 47424270 0.000176134−32.69210526 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4742705147443808 4.14E−06 −20.4284629 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2147453670 47453712 0.001694183 23.04736842 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr21 47456828 47484922 3.21E−15 −23.81643714Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 47529356 47531773 1.18E−06−31.52359307 Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 4755679847561836 0.000232488 −29.38847053 Hypo-methylated NEPC|CRPC-Adeno DMRschr21 47799144 47799212 4.03E−08 22.43387914 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr21 47813364 47813573 0.001221669 −31.41597222Hypo-methylated NEPC|CRPC-Adeno DMRs chr21 47836653 47836809 8.09E−05−24.35706121 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 1708199717083507 2.01E−18 26.23637974 Hyper-methylated NEPC|CRPC-Adeno DMRschr22 17566412 17566990 2.11E−12 29.53152352 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 17600489 17600888 5.60E−10 24.43126123Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 17679616 17679819 4.65E−07−36.56061298 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 1774525617745813 0.002927544 −32.58235867 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 17795344 17795579 0.000549237 −49.48621554 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 17883966 17884038 0.001694183 −31.20840991Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 18255268 18256402 0.005297267−20.29991646 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 1829162118291900 0.000412306 −39.32090643 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 18451167 18451225 0.003525992 −58.417154 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 19017888 19020625 0.00213974  −24.92353801Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 19138290 19138349 0.00015387225.79181287 Hv per-methylated NEPC|CRPC-Adeno DMRs chr22 1917119319172162 0.004750844 −21.87134503 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 19652858 19652943 5.50E−05 −22.75230901 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 19799811 19799875 0.000549237 25.43107769Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 19879579 198796410.000549237 −38.98320951 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2219889511 19890171 0.000184724 −48.76962081 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 20142515 20142953 9.43E−06 −32.26425439Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 20161417 20161962 0.002859601−35.60833333 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 2022062420220855 0.001694183 −28.91033138 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 20267861 20268321 0.000101637 −29.23521767 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 21083590 21083979 1.09E−05 −20.23391813Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 22012345 22012676 8.34E−08−21.51363895 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 2324417223267476 0.009285355 −27.44089912 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 24109380 24109600 0.002976353 29.31145572 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 24814938 24816978 0.000382054 −22.05648632Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 25081972 25082083 5.17E−0629.34556087 Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 2567882225678981 2.19E−08 24.54682903 Hyper-methylated NEPC|CRPC-Adeno DMRschr22 26176100 26176224 0.001694183 −21.98508772 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 27895126 27895313 0.000407892 −21.49534413Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 27900385 27900603 0.001694183−46.3869883 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 28070020 280701300.003475856 −27.51804511 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2228901886 28901942 0.001694183 −38.28274854 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 29811382 29811570 1.37E−07 −25.5839972Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 30086484 30100682 0.00025311 −34.42611463 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 3060126030601640 9.81E−07 −36.71345029 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 31032454 31033046 0.000177856 −25.91453242 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 31218825 31218864 0.001694183 25.16666667Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 32928018 329284720.009458442 −28.2748538 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2233197453 33197838 4.12E−16 25.54268701 Hyper-methylated NEPC|CRPC-AdenoDMRs chr22 34502800 34606261 0.009285355 −27.20856661 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 35796905 35797018 0.007379618 −20.39766082Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 35937309 35938671 2.87E−08−21.23997156 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 3673027636730344 0.001694183 41.8742342 Hyper-methylated NEPC|CRPC-Adeno DMRschr22 37302815 37308342 0.000476227 −32.00818017 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 37456636 37456867 5.50E−05 −20.18518519Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 37736873 37740472 0.000303685−34.93633048 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 3777668537779628 0.004750844 −28.65837212 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 37888713 37888806 0.000581135 28.10307018 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 39549340 39549572 5.75E−05 −21.17843881Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 39865530 39865971 0.000176134−42.67516447 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 4004265240043087 1.77E−05 −37.44154705 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 40094351 40095658 0.001802623 −44.54761905 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 40419901 40424993 0.000209051 23.93421053Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 40814817 408149500.000488426 −28.28737353 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2242678710 42678986 0.007136365 31.89947646 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 43511971 43521598 0.001802623 20.44340017Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 43739984 43740052 2.76E−0530.18724696 Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 4489301044893216 0.006890179 −20.19955991 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 44939749 44939893 0.002976353 28.12698413 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 46261813 46263196 1.20E−10 33.14653129Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 46301416 46301937 2.64E−09−37.12364055 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 4630748946307987 0.001931256 −23.88459831 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 46849116 46849770 5.55E−07 −20.63170908 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 46859512 46859637 0.00222033  −23.01388889Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 46869505 46870081 0.000488426−25.33073424 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 4687374146873999 0.001694183 −30.66081871 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 47003738 47003834 0.003113626 30.23879142 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 47014443 47014913 5.36E−06 −39.08979403Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 47048640 47049236 3.58E−06−36.15611492 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 4709233847092652 4.34E−06 −35.36828875 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 47311232 47311549 0.001694183 −38.96490532 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 47444995 47447605 4.20E−05 −40.47353736Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 47561271 47562616 1.22E−05−46.06201814 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 4890247048903232 0.001545937 −22.72856037 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 49024769 49025241 8.47E−06 −23.95748409 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 49096970 49097738 0.000549237 −24.15335889Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 50521389 50521550 0.000176134−30.66419956 Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 5055315250553314 0.000176134 −36.62126556 Hypo-methylated NEPC|CRPC-Adeno DMRschr22 50681333 50681843 5.17E−06 −24.96212121 Hypo-methylatedNEPC|CRPC-Adeno DMRs chr22 50706027 50706503 5.78E−15 29.97591133Hyper-methylated NEPC|CRPC-Adeno DMRs chr22 50757131 507579110.002989545 −29.35456064 Hypo-methylated NEPC|CRPC-Adeno DMRs chr2250967984 50968018 0.001694183 30.68412698 Hyper-methylatedNEPC|CRPC-Adeno DMRs chr22 51143790 51144204 6.36E−10 −24.19919468Hypo-methylated NEPC|CRPC-Adeno DMRs chr22 51168048 51168130 0.000549237−37.12180451 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 2720584 27262814.29E−06 −29.85374635 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 27731012779752 0.000253274 −22.22647528 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 3264783 3264828 0.000184724 26.86074561 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 3643936 3659640 0.005737741 −33.6745313Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 9175379 9175429 0.00127405127.68190476 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 9984106 100066172.91E−07 −29.79629462 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 1426201314262212 2.97E−08 23.37515759 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX16801615 16801690 0.000176134 −22.32534722 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 17609935 17635448 0.00222033  −40.36451484Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 22474666 22620452 0.004915778−22.59945489 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 22803914 230937376.76E−11 −30.25333378 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 2310610023329924 7.95E−06 −27.50264284 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX23393552 23447400 5.75E−05 −32.49538012 Hypo-methylated NEPC|CRPC-AdenoDMRs chrX 23518215 23611170 0.000855523 −20.92451462 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 23784306 23786342 0.001549499 −27.92872807Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 29933339 30166275 1.97E−06−20.48019641 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 30672701 306975960.000224358 22.3538755 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX34960807 35813099 2.98E−13 −21.40294562 Hypo-methylated NEPC|CRPC-AdenoDMRs chrX 37096555 37167996 0.000542154 −25.15165186 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 37220451 37351061 0.004750844 −24.76615497Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 37365637 37402391 0.000601653−26.88410176 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 37402563 374134931.66E−05 −26.91652816 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 3776512237765701 0.000324528 −20.82286722 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 37857688 37857750 0.001694183 −40.02777778 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 39921467 39923700 1.55E−06 −47.82794225Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 46937609 46938655 3.71E−0924.15384888 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 47437074 474410890.001197874 20.67406964 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX48186461 48214822 0.003113626 −22.94805478 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 48859617 48859655 0.003525992 −27.71428571Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 50213079 50213171 0.00928535526.17432383 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 50258021 503795270.000104758 −38.63839009 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX53077254 53079116 5.12E−07 −21.06639217 Hypo-methylated NEPC|CRPC-AdenoDMRs chrX 54765487 54765561 0.001694183 −26.05214425 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 55198670 55383234 8.14E−05 −27.14442838Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 56264765 56406495 0.000218704−21.48272685 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 56407346 565323200.000515039 −24.26122076 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX58293909 58296963 1.88E−05 −20.59750576 Hypo-methylated NEPC|CRPC-AdenoDMRs chrX 64626762 64627130 1.17E−08 22.8738761 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 64674766 64721864 0.002859601 −27.41517962Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 64769732 64770733 0.000476227−26.77719298 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 66321282 667157621.27E−06 −35.79131292 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 6678513367238838 0.000489849 −34.76101569 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 67679302 67696792 0.000176134 −24.54530874 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 67885494 67907846 5.26E−14 −24.08293411Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 68115105 68115155 0.003932932−37.87613301 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 68441405 684415370.002094266 23.41351875 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX68725816 68726201 7.49E−10 31.70154205 Hyper-methylated NEPC|CRPC-AdenoDMRs chrX 68775663 68810730 4.58E−05 −24.2713146 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 68892582 69307180 3.63E−12 −20.8848458Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 69936578 70140243 0.000220189−26.51720795 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 70887371 708881980.000484821 −26.23047429 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX71034556 71088924 0.000400293 −24.80025585 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 71090186 71095206 8.67E−07 −34.83030814Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 72288762 72319796 4.76E−08−21.21057288 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 73755675 737569561.83E−19 −23.56274177 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 7486661074933064 0.001694183 −21.29473684 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 77209729 77209802 0.005737741 27.72631579 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 77395394 78605634 0.003525992 −23.00171967Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 78667235 79076667 1.08E−06−40.70439006 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 79617823 798303284.44E−09 −38.70621162 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 8276319882763232 5.17E−06 50.1083865 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX90689802 90690100 7.87E−11 25.88303258 Hyper-methylated NEPC|CRPC-AdenoDMRs chrX 90711585 90990226 0.000128534 −23.5898771 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 91037116 91037166 0.007136365 32.97593985Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 95166938 95495115 0.000176134−33.70090852 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 95524551 958394081.41E−05 −22.52965294 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 9588213695898216 0.000549237 −20.42653061 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 95949989 96082957 1.37E−07 −26.44707049 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 100673192 100673741 1.50E−06 −25.30832473Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 100830003 1008483420.001883547 −27.11148325 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX100983206 100997072 2.76E−05 −35.76457135 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 102475605 102475704 0.000176134 27.50032895Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 103463974 1034952690.000263522 −26.50762483 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX103498818 103499060 2.29E−05 20.92132783 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 104195783 105065068 3.06E−09 −40.29809575Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 105203773 105956548 7.18E−11−36.16619138 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 106567446106568159 3.96E−05 40.64011925 Hyper-methylated NEPC|CRPC-Adeno DMRschrX 108332864 108675307 4.24E−06 −38.3554929 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 109648004 109932415 0.000154411 −30.72858371Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 111129539 111307181 4.65E−07−33.14695397 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 111356722112022425 9.58E−10 −28.7507352 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX112250609 113745216 4.92E−18 −30.62801974 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 114528373 114542387 0.000549237 −25.56691729Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 115066914 1153045210.003977693 −26.3951806 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX115375230 116974824 1.40E−12 −30.59463135 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 117411216 117411307 0.00489825  23.83759398Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 118234149 1182845340.002094266 −20.02219519 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX118827635 118827785 0.000716333 −25.97511371 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 120135432 120135503 0.000484821 20.00156691Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 125299773 125299840 4.65E−0732.95220423 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 125300174125300222 0.000176134 27.12867647 Hyper-methylated NEPC|CRPC-Adeno DMRschrX 125715144 125715287 1.27E−07 25.24954245 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 128926390 128926468 0.000176134 −42.42127193Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 129087400 1290874880.00041315  34.12610939 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX129205782 129218327 0.00222033  24.61198938 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 130518133 130518205 0.000209051 −31.70398724Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 130929727 1309372810.000175398 −20.12668098 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX133119214 133119361 0.005737741 20.30547386 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 134096722 134099911 0.000711935 −30.25339984Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 134156102 134156681 1.44E−11−22.37287347 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 135294705135301330 0.001012154 −23.23746499 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 135332851 135333598 4.92E−18 24.38912671 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 135534743 135534783 0.004750844 23.34535481Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 135849959 1358503450.000101021 27.60472348 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX136114047 136114194 0.000101637 21.06562703 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 136304922 136436542 0.002376793 −25.44929938Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 136510347 136512686 1.33E−0621.1966324 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 136647741136648946 1.79E−11 30.26218277 Hyper-methylated NEPC|CRPC-Adeno DMRschrX 138066426 138259844 0.000148603 −28.48210231 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 139013573 139013837 5.01E−05 −20.78484405Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 139585926 139586944 1.31E−0523.42806878 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 139587125139587898 2.35E−05 32.79448622 Hyper-methylated NEPC|CRPC-Adeno DMRschrX 141479306 141577115 0.001012154 −28.0357708 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 142723753 142723827 0.000549237 37.68646617Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 144712727 144713078 4.71E−05−20.95599243 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 144899533144900116 1.01E−16 24.06204331 Hyper-methylated NEPC|CRPC-Adeno DMRschrX 148734113 148841487 1.90E−05 −26.55809176 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 148971392 149022094 6.29E−06 −27.00965132Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 149208011 1495300210.000489991 −28.07584598 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX150345630 150345855 3.96E−05 28.23133541 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 151142874 151142959 0.000542161 23.7860771Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 152069090 152101505 1.11E−09−24.79378286 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152662396152663353 8.96E−05 −32.37702068 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 152696875 152699547 0.001694183 −27.63826754 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 152711226 152711615 8.67E−07 −39.54041835Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152742281 152746419 9.82E−05−29.59722156 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152747840152752177 0.000488426 −25.04218143 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 152767560 152767982 0.002094266 −29.39988629 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 152785675 152792846 2.91E−06 −26.71736998Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152793351 1527968310.000721524 −26.72328498 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX152802556 152804111 0.001555574 −26.75108843 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 152840373 152840964 0.000209051 −22.93434148Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152845574 152845623 9.54E−05−29.67856209 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152876129152876287 0.001694183 −22.57135076 Hypo-methylated NEPC|CRPC-Adeno DMRschrX 152902993 152905638 7.44E−06 −27.43059385 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 152958334 152958427 0.000549237 −37.45497076Hypo-methylated NEPC|CRPC-Adeno DMRs chrX 152960427 1529716920.00302923  20.7735313 Hyper-methylated NEPC|CRPC-Adeno DMRs chrX153053632 153054041 0.002976353 −23.40689521 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrX 153127389 153127622 0.000291618 24.02286487Hyper-methylated NEPC|CRPC-Adeno DMRs chrX 153171055 1531711600.000581135 −28.11374269 Hypo-methylated NEPC|CRPC-Adeno DMRs chrX153215869 153215990 0.004750844 21.00449785 Hyper-methylatedNEPC|CRPC-Adeno DMRs chrX 153381855 153382276 0.000200845 −27.32503612Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 6132527 6720539 0.000194541−27.9042161 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 6787176 67909110.000214872 −27.03728214 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY6790972 6954468 0.000467288 −27.11883899 Hypo-methylated NEPC|CRPC-AdenoDMRs chrY 7525221 7645361 1.80E−11 −23.65777201 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrY 8121938 8147959 1.65E−05 −27.79421803Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 10009069 10010109 0.002094266−24.02090643 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 13263288 133107600.002002439 −20.68611747 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY13312337 13312912 5.69E−07 −31.49477861 Hypo-methylated NEPC|CRPC-AdenoDMRs chrY 13314671 13328687 9.09E−05 −29.49886878 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrY 14481624 14494988 0.001694183 −42.81732804Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 14558515 14658116 0.000669876−23.56600754 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 14995636 153165406.42E−05 −25.42790879 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 1539467415421396 0.000324528 22.67280702 Hyper-methylated NEPC|CRPC-Adeno DMRschrY 17567474 17568277 3.49E−15 −22.13593024 Hypo-methylatedNEPC|CRPC-Adeno DMRs chrY 19155241 19472657 6.82E−09 −26.06944582Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 21238594 21239217 1.10E−17−24.14056622 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 24513436 287483622.59E−06 −32.66231594 Hypo-methylated NEPC|CRPC-Adeno DMRs chrY 5899005459033064 0.000154148 −25.62277649 Hypo-methylated NEPC|CRPC-Adeno DMRs

Interrogation of the end of treatment cases within this cohort (with atleast 10% tumor content(Benelli, Romagnoli, and Demichelis (2018)Bioinformatics 34:1642-1649)) revealed similar methylation profiledistribution as the CRPC-Adeno cases treated with potent AR pathwayinhibitors (FIG. 12D) and the combined set demonstrated significantmethylation differences between CRPC-Adeno and CRPC-NE patients(p=0.0031). Notably, the two CRPC-Adeno cases that harboreddifferentially methylated region (DMR) profiles compatible with CRPC-NEwere from patients with visceral metastases as well as other featurescommonly seen in CRPC-NE (i.e., WCM119 developed radiographicprogression on enzalutamide in the setting of a low serum PSA andelevated serum neuroendocrine markers; WCM14 tumor harbored concurrentMYCN amplification and deletion of RB1, which are often enriched inCRPC-NE).

It was found that CRPC-NE is associated with both genomic and epigenomicfeatures that distinguish this resistant subtype from CRPC-Adeno, andthese alterations are detectable by ctDNA. While WES and WGBS allowedfor the characterization of global patterns and tumor heterogeneity in apatient cohort with relatively high metastatic tumor burden, a molecularclassifier for CRPC-NE would be useful if it can be applied at allstages of the disease even in situations with lower tumor burden. Thiswould require a more sensitive targeted assay to run at deeper coverageamenable to lower TC plasma samples. A targeted set of genomic andepigenomic lesions that can identify CRPC-NE was therefore tested usingcfDNA. When combining the presence or absence of CRPC-NE-associatedfeatures including genomic deletion of mutation of TP53, RB1, and CYLD;lack of mutation or focal gain of AR; and aggregated hypo- andhyper-methylation of 20 differential sites (Table 6) (NEPC featurescore, see methods), cfDNA was robust in identifying individuals withCRPC-NE confirmed by histologic analysis of their metastatic biopsy(P=0.000444) (FIG. 12E). Although DNA methylation in itself is a strongclassifier of CRPC-NE, it was reasoned that the combination with genomicalterations, likely earlier events, would enable the futureidentification of high risk cases at earlier stages. These data nominatea ctDNA classifier as a potential biomarker for detecting CRPC-NEnon-invasively.

Recent metastatic biopsy studies have uncovered the landscape of genomicand epigenomic alterations enriched in metastatic CRPC compared toprimary prostate tumors (Abida et al. (2019) Proc Natl Acad Sci USA116:11428-11436; Armenia et al. (2018) Nat Genet 50:645-651; Robinson etal. (2015) Cell 161:1215-1228; Quigley et al. (2018) Cell 175:889), yetthere is still much to learn regarding the sequence of molecular eventsthat occurs during prostate cancer progression and therapy resistanceand the degree of heterogeneity that underlies different stages of thedisease. Resistance patterns have largely fallen into two categories:AR-driven and non-AR driven (Watson, Arora, and Sawyers (2015) Nat RevCancer 15:701-711). The vast majority of castration resistant tumors areAR-driven, and this can be mediated through AR gene amplification,mutation, splicing, other structural variants, or other means. SpecificAR alterations detected by blood sampling, such as AR amplification inctDNA or AR-V7 splice variant expression in circulating tumor cells,have been associated with poor response and outcomes in patients treatedwith the AR-targeted drugs abiraterone or enzalutamide (Romanel et al.(2015) Sci Transl Med 7:312re310; Azad et al. (2015) Clin Cancer Res21:2315-2324; Antonarakis et al. (2014) N Engl J Med 371:1028-1038).This study and others (Romanel et al. (2015) Sci Transl Med 7:312re310;Quigley et al. (2018) Cell 175:889; Viswanathan et al. (2018) Cell174:433-447.e419; Henzler et al. (2016) Nat Commun 7:13668) supportcontinued evolution of AR gene alterations during disease progression.Non-AR driven disease is less common in CRPC and the mechanismsunderlying AR independence are less clear. One increasingly recognizedmechanism is the development of lineage plasticity, by which the tumorcells adopt alternative lineage and oncogenic programs to grow despitesuppressed AR signaling (Beltran et al. (2019) Clin Cancer Res25:6916-6924). One extreme manifestation of this is the transformationfrom a luminal prostate adenocarcinoma to a CRPC-NE phenotype, definedby the acquisition of histologic features similar to small cell lungcancer (Epstein et al. (2014) Am J Surg Pathol 38:756-767) andassociated with distinct molecular alterations (Aggarwal et al. (2018) JClin Oncol JCO2017776880; Benelli, Romagnoli, and Demichelis (2018)Bioinformatics 34:1642-1649). It has been reported that up to 15-20% ofpatients develop CRPC-NE in late stages of their disease (Abida et al.(2019) Proc Natl Acad Sci USA 116:11428-11436; Aggarwal et al. (2018) JClin Oncol JCO2017776880; Bluemn et al. (2017) Cancer Cell32:474-489.e476). Similar to small cell lung cancer and other small cellneuroendocrine carcinomas(9), CRPC-NE is enriched with genomic loss ofTP53 and RB/(Abida et al. (2019) Proc Natl Acad Sci USA 116:11428-11436;Benelli, Romagnoli, and Demichelis (2018) Bioinformatics 34:1642-1649;Mu et al. (2017) Science 355:84-88). However, loss of these genes canalso occur in non-neuroendocrine prostate cancer (Robinson et al. (2015)Cell 161:1215-1228). In EGFR-mutated lung adenocarcinomas, the presenceof TP53 and RB1 loss predisposes patients to later transformation tosmall cell lung cancer after EGFR inhibitor therapy (Lee et al. (2017) JClin Oncol 35:3065-3074; Offin et al. (2019) J Thorac Oncol14:1784-1793). The timing of these events and other molecularalterations during CRPC-NE progression has not been established; thedata indicates that they can also be acquired early. DNA methylation andtranscriptome analyses have also pointed to specific defining featuresof CRPC-NE that can improve upon genomics for CRPC-NE disease detection.In the current study, it was found that both genomic and epigenomicfeatures of CRPC-NE are identifiable in patients non-invasively throughplasma ctDNA analysis. The diagnosis of CRPC-NE has clinicalimplications as these patients can be considered for platinum-basedchemotherapy (Aparicio et al. (2013) Clin Cancer Res 19:3621-3630;Aparicio et al. (2016) Clin Cancer Res 22:1520-1530) or other non-ARtargeted approaches, rather than AR-targeted drugs.

In this study, several prostate cancer alterations shared between bothadenocarcinoma and CRPC-NE were also identified, supporting a same cellof origin, though certain genomic alterations (such as AR, TP53, andRB1) had different prognostic value in patients based on theirhistologic subtype. A genome-wide approach was taken in order tocharacterize the clonal and subclonal heterogeneity in advanced prostatecancer. Similar to prior studies utilizing targeted DNA or WES (Wyatt etal. (2017) J Natl Cancer Inst 109: doi: 10.1093/jnci/djx118;Adalsteinsson et al. (2017) Nat Commun 8:1324), there was overall highconcordance of alterations shared between cfDNA and matched tumorbiopsies within individual patients. Allele-specific analysis allowedfor a more refined estimation of subclonal diversity. In general,comparison across patients, metastases, and between plasma and biopsiespointed to less heterogeneity in CRPC-NE compared with CRPC-Adeno. Thisobservation, as well as data from published rapid autopsy studies (Kumaret al. (2016) Nat Med 22:369-378; Aryee et al. (2013) Sci Transl Med5:169ra110), points to higher intra-individual homogeneity acrossmetastases in later stages of the disease. A proposed model of prostatecancer progression towards CRPC-NE building upon published work in thefield is depicted in FIG. 14 . While prior studies have supported amonoclonal origin of metastatic prostate cancer (Haffner et al. (2013) JClin Invest 123:4918-4922; Liu et al. (2009) Nat Med 15:559-565) withmetastatic lesions often traceable back to a founding clone within theprimary tumor (Kumar et al. (2016) Nat Med 22:369-378), tumors dosubsequently acquire alterations with disease progression and treatmentresistance. Polyclonal spread (Gundem et al. (2015) Nature 520:353-357;Hong et al. (2015) Nat Commun 6:6605) in later stages further leads tointra-patient heterogeneity, particularly of subclonal alterations (asdetected here through allele-specific copy number analysis of ctDNA).Evolution of these subclones can contribute to cancer therapy resistance(Burrell and Swanton (2014) Mol Oncol 8:1095-1111; Parikh et al. (2019)Nat Med 25:1415-1421). During the transition towards CRPC-NE and ARindependence, the data supports likely selection of a dominant tumorclone (potentially harboring combined loss of RB1 and TP53) thatpersists and dominates due to selective pressures of therapy resultingin more stringent bottlenecks in the subclonal makeup of the tumor.Therefore, although collective clinical and preclinical data supportsCRPC-NE arising through trans-differentiation from a prostateadenocarcinoma precursor, the data also indicates that there can bedominance or clonal selection of a resistant clone during this process,and that these are not two mutually exclusive models of clonalevolution.

It was also found that DNA methylation profiles change with CRPC-NE,which is detectable both in tissues and in cfDNA. DNA methylationpatterns have also been reported to be consistent across sites ofmetastases in men with lethal CRPC-Adeno (Yegnasubramanian et al. (2004)Cancer Res 64:1975-1986; Aryee et al. (2013) Sci Transl Med 5:169ra110),supporting the use of methylation as a relatively stable biomarker fordetecting specific resistance patterns. Methylation profiles also pointto differential epigenetic regulation of key genes involved in CRPC-NEand can also point to new therapeutic avenues.

While the CRPC-NE subtype was focused on, it was recognized that otherresistance subtypes also exist even within non-AR driven disease (Bluemnet al. (2017) Cancer Cell 32:474-489.e476). Nonetheless, these newobservations highlight the feasibility and promise of a combinedgenomic/epigenomic cfDNA approach to identify men with advanced CRPC-NEand provides insights into the degree of intra-patient heterogeneitythat exists at different stages of disease progression.

Example 3: Custom Sequencing Panel

Based on the study results from Beltran et al. (2020) J. Clin.Investigation 130(4):1653-1668, an approach was designed based on adedicated custom next-generation sequencing panel to quantify thepresence of CRPC-Adeno and of CRPC-NE signal in cell-free DNA (cfDNA) ofpatients with metastatic castrate-resistant prostate cancer (mCRPC). Thepanel exploits the DNA methylation signal in the circulation as adiagnostic and prognostic biomarker while also providing an estimationof cancer disease burden. This aids the detection of treatmentresistance to androgen receptor signaling inhibitors and helpsmonitoring disease dynamics. In silico data focus on mCRPC, thisapproach can be extended to earlier disease states.

The custom design stems from a series of computational analyses,including assessment of preliminary performance measures on discoveryand test sample sets, and is composed of multiple modules specificallytailored to this precise clinical setting. High-quality data wasintegrated from public and internal cohorts, including DNA methylationprofiles of tissue biopsies and cfDNA from mCRPC patients, white bloodcells, and other sources. This procedure allowed for the nomination of aseries of genomic regions in which DNA methylation reflects the state ofdisease. In addition, a knowledge-based approach based on an extensiveliterature review and the interrogation of gene expression data fromboth patients and established biological models allowed prioritizationof the inclusion of informative sites for the implementation of theultimate classifiers.

The approach exploits the exquisite tissue specificity of DNAmethylation to obtain:

1—A robust estimation of tumor content from cfDNA;

2—A score that captures the evidence of neuroendocrine features andtherefore also informative of neuroendocrine treatment resistantphenotype emergence;

3—A score that captures the evidence of CRPC-Adeno features;

4—Additional information through the sequencing profiles of knownprostate cancer related genes and regulatory elements.

This multilayered approach is implemented through a targeted strategythat minimize the sequencing cost while retaining sufficient informationto achieve the above mentioned tasks.

Detailed information on regions contributing to the multilayeredapproach for a total of about 100K bp of genomic sequence and theinclusion of about 20K CpG is shown in Table 14.

TABLE 14 start_hg19 end_hg19 width reg_id pval adjPval mean_a mean_bdeltaBeta chr1 32237823 32238325 503 1:32237823-32238325  3.3E−453.02E−42 84.4190582 1.02922257 83.38983566 chr1 43814069 43814458 3901:43814069-43814458 6.12E−26 3.28E−24 9.08307376 91.7970836 −82.7140099chr1 151345023 151345348 326 1:151345023-151345348 1.37E−38 5.92E−362.61611719 94.2279946 −91.6118774 chr1 151810787 151811004 2181:151810787-151811004 5.31E−50 9.36E−47 90.3863775 0.3447001 90.04167737chr2 19561227 19561809 583 2:19561227-19561809 3.08E−36 9.42E−3490.5382869 5.48781566 85.05047125 chr2 63283706 63284232 5272:63283706-63284232 1.77E−32 2.98E−30 89.6415386 5.5931654 84.04837319chr2 177030050 177030328 279 2:177030050-177030328 5.74E−30 5.69E−2889.9319788 5.70881926 84.22315955 chr2 201450223 201450843 6212:201450223-201450843 5.71E−43 4.68E−40 86.0864978 1.7668975884.31960025 chr3 50378091 50378764 674 3:50378091-50378764 8.25E−61 6.3E−57 87.911632 0.19797753 87.71365445 chr3 122296269 122296878 6103:122296269-122296878   6E−42 4.04E−39 88.3720248 1.61277131 86.7592535chr3 124860516 124860971 456 3:124860516-124860971  3.9E−54 1.49E−5088.3411556 0.23879672 88.10235885 chr5 958708 959241 534 5:958708-9592411.18E−35 3.39E−33 5.85725265 88.6846504 −82.8273977 chr5 3187966 3188474509 5:3187966-3188474 2.63E−35 7.25E−33 9.41259588 93.6645583−84.2519625 chr5 180230667 180231294 628 5:180230667-180231294 2.27E−483.72E−45 85.3018416 0.5135224 84.78831919 chr6 13014771 13015321 5516:13014771-13015321 1.31E−23 5.02E−22 11.0388355 91.994453 −80.9556175chr6 15505245 15505560 316 6:15505245-15505560 1.35E−41 8.61E−393.73131251 96.2432406 −92.511928 chr6 26271093 26271927 8356:26271093-26271927 2.27E−47 2.74E−44 88.3044313 1.09576558 87.2086657chr7 73245339 73245852 514 7:73245339-73245852 2.51E−39  1.2E−364.68822041 94.1459188 −89.4576984 chr7 129425230 129426032 8037:129425230-129426032 1.77E−45 1.77E−42 86.066727 2.42468618 83.64204084chr8 56852048 56852390 343 8:56852048-56852390 9.67E−30 9.27E−2891.9309828 4.96191198 86.96907078 chr8 99960398 99960680 2838:99960398-99960680 5.34E−40 2.91E−37 90.5638848 2.5593572 88.00452764chr8 143625497 143626067 571 8:143625497-143626067 3.31E−29 2.94E−2710.2304561 90.4788259 −80.2483698 chr8 145104006 145104459 4548:145104006-145104459 1.61E−59 9.24E−56 91.5013281 0.83535244 90.6659757chr10 6297648 6298011 364 10:6297648-6298011 4.83E−34  1.1E−3113.2857089 96.1793779 −82.893669 chr10 22541895 22542245 35110:22541895-22542245 1.09E−51 2.77E−48 86.0149881 0.74220323 85.27278488chr11 393838 394389 552 11:393838-394389 4.73E−31 5.79E−29 6.9275795188.4597663 −81.5321868 chr11 47416258 47416635 378 11:47416258-474166352.04E−45 1.95E−42 85.1533209 0.72233373 84.43098719 chr11 6397467263975126 455 11:63974672-63975126 7.04E−53 2.31E−49 84.93540320.32106936 84.61433388 chr11 165408329 65408666 338 11:65408329-654086662.11E−29 1.93E−27 91.1600164 7.53063149 83.62938492 chr11 6720499667205391 396 11:67204996-67205391 4.68E−51 8.93E−48 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chr1 18809102 18809106 51:18809102-18809106 1.64E−40 6.63E−38 36.7727472 90.0271183 −53.2543711chr1 18809112 18809115 4 1:18809112-18809115 1.64E−40 6.63E−3836.7727472 90.0271183 −53.2543711 chr1 18809126 18809129 41:18809126-18809129 1.64E−40 6.63E−38 36.7727472 90.0271183 −53.2543711chr1 18809494 18809497 4 1:18809494-18809497 1.64E−40 6.63E−3836.7727472 90.0271183 −53.2543711 chr1 20141125 20141128 41:20141125-20141128  1.5E−15 3.59E−14 32.2386973 80.1381529 −47.8994555chr1 20141136 20141139 4 1:20141136-20141139  1.5E−15 3.59E−1432.2386973 80.1381529 −47.8994555 chr1 20141322 20141325 41:20141322-20141325  1.5E−15 3.59E−14 32.2386973 80.1381529 −47.8994555chr1 20141344 20141347 4 1:20141344-20141347  1.5E−15 3.59E−1432.2386973 80.1381529 −47.8994555 chr1 20141404 20141407 41:20141404-20141407  1.5E−15 3.59E−14 32.2386973 80.1381529 −47.8994555chr1 20141442 20141445 4 1:20141442-20141445  1.5E−15 3.59E−1432.2386973 80.1381529 −47.8994555 chr1 20141462 20141465 41:20141462-20141465  1.5E−15 3.59E−14 32.2386973 80.1381529 −47.8994555chr1 22195529 22195532 4 1:22195529-22195532 5.41E−06 2.09E−05 42.472583.6422932 −41.1697932 chr1 32252163 32252166 4 1:32252163-322521662.06E−05 6.77E−05 17.3888889 71.0847953 −53.6959064 chr1 3225222932252232 4 1:32252229-32252232 2.06E−05 6.77E−05 17.3888889 71.0847953−53.6959064 chr1 32252239 32252242 4 1:32252239-32252242 2.06E−056.77E−05 17.3888889 71.0847953 −53.6959064 chr1 32252264 32252268 51:32252264-32252268 2.06E−05 6.77E−05 17.3888889 71.0847953 −53.6959064chr1 32252425 32252428 4 1:32252425-32252428 2.06E−05 6.77E−0517.3888889 71.0847953 −53.6959064 chr1 45103348 45103351 41:45103348-45103351 2.49E−08 1.68E−07 41.7444444 85.0616855 −43.317241chr1 45103390 45103393 4 1:45103390-45103393 2.49E−08 1.68E−0741.7444444 85.0616855 −43.317241 chr1 45106491 45106494 41:45106491-45106494 2.49E−08 1.68E−07 41.7444444 85.0616855 −43.317241chr1 156215343 156215346 4 1:156215343-156215346   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215371 156215374 41:156215371-156215374   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215401 156215404 4 1:156215401-156215404   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215416 156215420 51:156215416-156215420   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215430 156215433 4 1:156215430-156215433   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215445 156215448 41:156215445-156215448   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215454 156215457 4 1:156215454-156215457   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215491 156215496 61:156215491-156215496   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215506 156215511 6 1:156215506-156215511   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215520 156215523 41:156215520-156215523   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215525 156215528 4 1:156215525-156215528   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215530 156215533 41:156215530-156215533   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215563 156215566 4 1:156215563-156215566   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215590 156215598 91:156215590-156215598   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215601 156215604 4 1:156215601-156215604   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215708 156215711 41:156215708-156215711   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215720 156215723 4 1:156215720-156215723   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 156215726 156215733 81:156215726-156215733   7E−11 7.84E−10 6.65714286 47.3143275 −40.6571846chr1 156215737 156215740 4 1:156215737-156215740   7E−11 7.84E−106.65714286 47.3143275 −40.6571846 chr1 203259747 203259755 91:203259747-203259755 1.99E−05 6.71E−05 0.67991453 44.7894737−44.1095592 chr1 203259757 203259761 5 1:203259757-203259761 1.99E−056.71E−05 0.67991453 44.7894737 −44.1095592 chr1 203259770 203259774 51:203259770-203259774 1.99E−05 6.71E−05 0.67991453 44.7894737−44.1095592 chr1 203259836 203259839 4 1:203259836-203259839 1.99E−056.71E−05 0.67991453 44.7894737 −44.1095592 chr1 203259850 203259853 41:203259850-203259853 1.99E−05 6.71E−05 0.67991453 44.7894737−44.1095592 chr1 203259921 203259924 4 1:203259921-203259924 1.99E−056.71E−05 0.67991453 44.7894737 −44.1095592 chr1 236311219 236311222 41:236311219-236311222 0.000285 0.000676 72.7111111 32.631579 40.07953216chr1 236311342 236311345 4 1:236311342-236311345 0.000285 0.00067672.7111111 32.631579 40.07953216 chr1 237129554 237129557 41:237129554-237129557 8.06E−11 8.94E−10 36.3496345 79.1940719−42.8444374 chr1 237134163 237134166 4 1:237134163-237134166 8.06E−118.94E−10 36.3496345 79.1940719 −42.8444374 chr1 237167480 237167483 41:237167480-237167483 8.06E−11 8.94E−10 36.3496345 79.1940719−42.8444374 chr1 237194084 237194087 4 1:237194084-237194087 8.06E−118.94E−10 36.3496345 79.1940719 −42.8444374 chr1 237194093 237194096 41:237194093-237194096 8.06E−11 8.94E−10 36.3496345 79.1940719−42.8444374 chr1 237194098 237194101 4 1:237194098-237194101 8.06E−118.94E−10 36.3496345 79.1940719 −42.8444374 chr1 237195314 237195317 41:237195314-237195317 8.06E−11 8.94E−10 36.3496345 79.1940719−42.8444374 chr1 237195411 237195414 4 1:237195411-237195414 8.06E−118.94E−10 36.3496345 79.1940719 −42.8444374 chr1 237212336 237212339 41:237212336-237212339 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237220609 237220612 4 1:237220609-237220612 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237220641 237220648 81:237220641-237220648 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237222098 237222101 4 1:237222098-237222101 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237222106 237222109 41:237222106-237222109 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237235121 237235124 4 1:237235121-237235124 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237235204 237235207 41:237235204-237235207 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237235522 237235525 4 1:237235522-237235525 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237235567 237235573 71:237235567-237235573 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237235607 237235610 4 1:237235607-237235610 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237256273 237256277 51:237256273-237256277 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237256316 237256319 4 1:237256316-237256319 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237265786 237265789 41:237265786-237265789 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237265877 237265880 4 1:237265877-237265880 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237267786 237267789 41:237267786-237267789 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237267812 237267815 4 1:237267812-237267815 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237267886 237267889 41:237267886-237267889 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237306208 237306211 4 1:237306208-237306211 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237306260 237306263 41:237306260-237306263 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237343254 237343257 4 1:237343254-237343257 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237359169 237359172 41:237359169-237359172 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237383690 237383693 4 1:237383690-237383693 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237392760 237392763 41:237392760-237392763 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237408076 237408079 4 1:237408076-237408079 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237408091 237408094 41:237408091-237408094 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237473057 237473061 5 1:237473057-237473061 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237473071 237473074 41:237473071-237473074 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237473091 237473094 4 1:237473091-237473094 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237473164 237473167 41:237473164-237473167 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237538162 237538165 4 1:237538162-237538165 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237584276 237584279 41:237584276-237584279 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237661252 237661255 4 1:237661252-237661255 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237661262 237661265 41:237661262-237661265 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237661322 237661325 4 1:237661322-237661325 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237693526 237693529 41:237693526-237693529 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237693534 237693537 4 1:237693534-237693537 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237699930 237699933 41:237699930-237699933 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237699938 237699941 4 1:237699938-237699941 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237699988 237699991 41:237699988-237699991 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 237809365 237809368 4 1:237809365-237809368 4.76E−339.29E−31 36.2774713 76.4897424 −40.2122712 chr1 237815260 237815263 41:237815260-237815263 4.76E−33 9.29E−31 36.2774713 76.4897424−40.2122712 chr1 241402493 241402496 4 1:241402493-241402496 3.52E−071.85E−06 79.8267974 37.8637771 41.9630203 chr1 241402516 241402519 41:241402516-241402519 3.52E−07 1.85E−06 79.8267974 37.8637771 41.9630203chr2 9248023 9248026 4 2:9248023-9248026 7.77E−05 0.000217 39.712588.375 −48.6625 chr2 9248368 9248371 4 2:9248368-9248371 7.77E−050.000217 39.7125 88.375 −48.6625 chr2 9248435 9248438 42:9248435-9248438 7.77E−05 0.000217 39.7125 88.375 −48.6625 chr2 92484699248472 4 2:9248469-9248472 7.77E−05 0.000217 39.7125 88.375 −48.6625chr2 25299679 25299682 4 2:25299679-25299682 0.000363 0.000822 35.382577.4900929 −42.1075929 chr2 25299815 25299818 4 2:25299815-252998180.000363 0.000822 35.3825 77.4900929 −42.1075929 chr2 25299928 252999314 2:25299928-25299931 0.000363 0.000822 35.3825 77.4900929 −42.1075929chr2 43102420 43102423 4 2:43102420-43102423 1.91E−06 8.28E−0679.5705416 38.5468082 41.02373335 chr2 43107259 43107262 42:43107259-43107262 1.91E−06 8.28E−06 79.5705416 38.5468082 41.02373335chr2 43107400 43107403 4 2:43107400-43107403 1.91E−06 8.28E−0679.5705416 38.5468082 41.02373335 chr2 43107414 43107417 42:43107414-43107417 1.91E−06 8.28E−06 79.5705416 38.5468082 41.02373335chr2 43107438 43107441 4 2:43107438-43107441 1.91E−06 8.28E−0679.5705416 38.5468082 41.02373335 chr2 43107456 43107459 42:43107456-43107459 1.91E−06 8.28E−06 79.5705416 38.5468082 41.02373335chr2 43107465 43107469 5 2:43107465-43107469 1.91E−06 8.28E−0679.5705416 38.5468082 41.02373335 chr2 43107514 43107517 42:43107514-43107517 1.91E−06 8.28E−06 79.5705416 38.5468082 41.02373335chr2 43107532 43107535 4 2:43107532-43107535 1.91E−06 8.28E−0679.5705416 38.5468082 41.02373335 chr2 43107650 43107653 42:43107650-43107653 1.91E−06 8.28E−06 79.5705416 38.5468082 41.02373335chr2 45235684 45235687 4 2:45235684-45235687  3.7E−07 1.91E−0618.9833333 67.2982456 −48.3149123 chr2 45235702 45235705 42:45235702-45235705  3.7E−07 1.91E−06 18.9833333 67.2982456 −48.3149123chr2 45235710 45235713 4 2:45235710-45235713  3.7E−07 1.91E−0618.9833333 67.2982456 −48.3149123 chr2 207972376 207972379 42:207972376-207972379 7.77E−05 0.000217 30.5746528 80.4016813−49.8270285 chr2 207972408 207972412 5 2:207972408-207972412 7.77E−050.000217 30.5746528 80.4016813 −49.8270285 chr2 220509654 220509657 42:220509654-220509657  2.9E−11 3.51E−10 31.31 76.8979532 −45.5879532chr2 220509693 220509696 4 2:220509693-220509696  2.9E−11 3.51E−10 31.3176.8979532 −45.5879532 chr2 220509705 220509709 5 2:220509705-220509709 2.9E−11 3.51E−10 31.31 76.8979532 −45.5879532 chr2 220509776 2205097794 2:220509776-220509779  2.9E−11 3.51E−10 31.31 76.8979532 −45.5879532chr2 220509830 220509833 4 2:220509830-220509833  2.9E−11 3.51E−10 31.3176.8979532 −45.5879532 chr2 241233035 241233038 4 2:241233035-2412330384.33E−06 1.73E−05 21.3222222 71.8994602 −50.577238 chr2 241233048241233051 4 2:241233048-241233051 4.33E−06 1.73E−05 21.322222271.8994602 −50.577238 chr2 241233055 241233059 5 2:241233055-2412330594.33E−06 1.73E−05 21.3222222 71.8994602 −50.577238 chr2 241233084241233088 5 2:241233084-241233088 4.33E−06 1.73E−05 21.322222271.8994602 −50.577238 chr2 241233090 241233094 5 2:241233090-2412330944.33E−06 1.73E−05 21.3222222 71.8994602 −50.577238 chr2 241233169241233172 4 2:241233169-241233172 4.33E−06 1.73E−05 21.322222271.8994602 −50.577238 chr2 241233214 241233217 4 2:241233214-2412332174.33E−06 1.73E−05 21.3222222 71.8994602 −50.577238 chr3 111431516111431520 5 3:111431516-111431520 0.000291 0.000676 41.125 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20111:133996134-133996334 chr11 134009435 134009635 20111:134009435-134009635 chr11 134017593 134017793 20111:134017593-134017793 chr12 7022809 7023009 201 12:7022809-7023009chr12 7023391 7023591 201 12:7023391-7023591 chr12 7023514 7023714 20112:7023514-7023714 chr12 7023602 7023802 201 12:7023602-7023802 chr127023621 7023821 201 12:7023621-7023821 chr12 7023653 7023853 20112:7023653-7023853 chr12 7023658 7023858 201 12:7023658-7023858 chr127023661 7023861 201 12:7023661-7023861 chr12 7023674 7023874 20112:7023674-7023874 chr12 7024271 7024471 201 12:7024271-7024471 chr127026393 7026593 201 12:7026393-7026593 chr12 7028638 7028838 20112:7028638-7028838 chr12 7030644 7030844 201 12:7030644-7030844 chr127031052 7031252 201 12:7031052-7031252 chr12 24983162 24983362 20112:24983162-24983362 chr12 25055130 25055330 201 12:25055130-25055330chr12 25055222 25055422 201 12:25055222-25055422 chr12 25055909 25056109201 12:25055909-25056109 chr12 25101877 25102077 20112:25101877-25102077 chr12 25101883 25102083 201 12:25101883-25102083chr12 25101895 25102095 201 12:25101895-25102095 chr12 25101920 25102120201 12:25101920-25102120 chr12 25102293 25102493 20112:25102293-25102493 chr12 25173836 25174036 201 12:25173836-25174036chr12 25186593 25186793 201 12:25186593-25186793 chr12 25188314 25188514201 12:25188314-25188514 chr12 25205089 25205289 20112:25205089-25205289 chr12 25205105 25205305 201 12:25205105-25205305chr12 25205106 25205306 201 12:25205106-25205306 chr12 25205346 25205546201 12:25205346-25205546 chr12 25205421 25205621 20112:25205421-25205621 chr12 25205476 25205676 201 12:25205476-25205676chr12 25205499 25205699 201 12:25205499-25205699 chr12 25205534 25205734201 12:25205534-25205734 chr12 25205574 25205774 20112:25205574-25205774 chr12 25205779 25205979 201 12:25205779-25205979chr12 25228574 25228774 201 12:25228574-25228774 chr12 25242608 25242808201 12:25242608-25242808 chr12 25249767 25249967 20112:25249767-25249967 chr12 25249792 25249992 201 12:25249792-25249992chr12 25257163 25257363 201 12:25257163-25257363 chr12 66582559 66582759201 12:66582559-66582759 chr12 66582875 66583075 20112:66582875-66583075 chr12 66582937 66583137 201 12:66582937-66583137chr12 70082891 70083091 201 12:70082891-70083091 chr12 70082956 70083156201 12:70082956-70083156 chr12 70087752 70087952 20112:70087752-70087952 chr12 70092965 70093165 201 12:70092965-70093165chr12 70093015 70093215 201 12:70093015-70093215 chr12 70093024 70093224201 12:70093024-70093224 chr12 70093031 70093231 20112:70093031-70093231 chr12 70093041 70093241 201 12:70093041-70093241chr12 70093044 70093244 201 12:70093044-70093244 chr12 70093075 70093275201 12:70093075-70093275 chr12 70093096 70093296 20112:70093096-70093296 chr12 70093156 70093356 201 12:70093156-70093356chr12 103351364 103351564 201 12:103351364-103351564 chr13 102527544102527744 201 13:102527544-102527744 chr13 102568895 102569095 20113:102568895-102569095 chr13 103054024 103054224 20113:103054024-103054224 chr14 21994247 21994447 201 14:21994247-21994447chr14 21994261 21994461 201 14:21994261-21994461 chr14 21994534 21994734201 14:21994534-21994734 chr14 22004936 22005136 20114:22004936-22005136 chr14 22004968 22005168 201 14:22004968-22005168chr14 22005138 22005338 201 14:22005138-22005338 chr14 22005250 22005450201 14:22005250-22005450 chr14 51448929 51449129 20114:51448929-51449129 chr14 51453070 51453270 201 14:51453070-51453270chr14 51454994 51455194 201 14:51454994-51455194 chr14 51561694 51561894201 14:51561694-51561894 chr14 51561947 51562147 20114:51561947-51562147 chr14 51562679 51562879 201 14:51562679-51562879chr14 75988668 75988868 201 14:75988668-75988868 chr14 75988698 75988898201 14:75988698-75988898 chr14 75988803 75989003 20114:75988803-75989003 chr14 93389325 93389525 201 14:93389325-93389525chr14 93389402 93389602 201 14:93389402-93389602 chr14 93389421 93389621201 14:93389421-93389621 chr14 93389608 93389808 20114:93389608-93389808 chr14 93392346 93392546 201 14:93392346-93392546chr14 93397922 93398122 201 14:93397922-93398122 chr15 74465912 74466112201 15:74465912-74466112 chr15 74466371 74466571 20115:74466371-74466571 chr15 74466644 74466844 201 15:74466644-74466844chr15 74466742 74466942 201 15:74466742-74466942 chr15 77285600 77285800201 15:77285600-77285800 chr15 77286921 77287121 20115:77286921-77287121 chr15 77287326 77287526 201 15:77287326-77287526chr15 77287363 77287563 201 15:77287363-77287563 chr15 77287365 77287565201 15:77287365-77287565 chr15 77287367 77287567 20115:77287367-77287567 chr15 77287372 77287572 201 15:77287372-77287572chr15 77287413 77287613 201 15:77287413-77287613 chr15 77287603 77287803201 15:77287603-77287803 chr15 77287626 77287826 20115:77287626-77287826 chr15 77287653 77287853 201 15:77287653-77287853chr15 77287660 77287860 201 15:77287660-77287860 chr15 77287815 77288015201 15:77287815-77288015 chr15 77308052 77308252 20115:77308052-77308252 chr15 77310699 77310899 201 15:77310699-77310899chr15 77319966 77320166 201 15:77319966-77320166 chr15 77320584 77320784201 15:77320584-77320784 chr15 77324558 77324758 20115:77324558-77324758 chr15 77327935 77328135 201 15:77327935-77328135chr16 29674500 29674700 201 16:29674500-29674700 chr16 29690229 29690429201 16:29690229-29690429 chr16 29690258 29690458 20116:29690258-29690458 chr16 29690403 29690603 201 16:29690403-29690603chr16 29707018 29707218 201 16:29707018-29707218 chr16 31146861 31147061201 16:31146861-31147061 chr16 31146924 31147124 20116:31146924-31147124 chr16 31146948 31147148 201 16:31146948-31147148chr16 31146983 31147183 201 16:31146983-31147183 chr16 74710849 74711049201 16:74710849-74711049 chr16 74712211 74712411 20116:74712211-74712411 chr16 74712746 74712946 201 16:74712746-74712946chr16 74725267 74725467 201 16:74725267-74725467 chr16 74734588 74734788201 16:74734588-74734788 chr16 74734607 74734807 20116:74734607-74734807 chr16 74734712 74734912 201 16:74734712-74734912chr16 74734758 74734958 201 16:74734758-74734958 chr16 88713133 88713333201 16:88713133-88713333 chr16 88716622 88716822 20116:88716622-88716822 chr16 88717296 88717496 201 16:88717296-88717496chr16 88717323 88717523 201 16:88717323-88717523 chr16 88717338 88717538201 16:88717338-88717538 chr16 88717339 88717539 20116:88717339-88717539 chr16 88717343 88717543 201 16:88717343-88717543chr16 88717349 88717549 201 16:88717349-88717549 chr16 88717362 88717562201 16:88717362-88717562 chr16 88717460 88717660 20116:88717460-88717660 chr17 1665153 1665353 201 17:1665153-1665353 chr171665223 1665423 201 17:1665223-1665423 chr17 1665255 1665455 20117:1665255-1665455 chr17 1665262 1665462 201 17:1665262-1665462 chr171665306 1665506 201 17:1665306-1665506 chr17 1666023 1666223 20117:1666023-1666223 chr17 1669468 1669668 201 17:1669468-1669668 chr171673720 1673920 201 17:1673720-1673920 chr17 1674913 1675113 20117:1674913-1675113 chr17 1679644 1679844 201 17:1679644-1679844 chr1727283357 27283557 201 17:27283357-27283557 chr17 27284731 27284931 20117:27284731-27284931 chr17 27287891 27288091 201 17:27287891-27288091chr17 27308510 27308710 201 17:27308510-27308710 chr17 27308790 27308990201 17:27308790-27308990 chr17 27332831 27333031 20117:27332831-27333031 chr17 27332981 27333181 201 17:27332981-27333181chr17 27333063 27333263 201 17:27333063-27333263 chr17 27333216 27333416201 17:27333216-27333416 chr17 27333358 27333558 20117:27333358-27333558 chr17 62007774 62007974 201 17:62007774-62007974chr17 62009521 62009721 201 17:62009521-62009721 chr17 62009583 62009783201 17:62009583-62009783 chr17 62009591 62009791 20117:62009591-62009791 chr17 62009596 62009796 201 17:62009596-62009796chr17 62009614 62009814 201 17:62009614-62009814 chr17 76970778 76970978201 17:76970778-76970978 chr17 76970979 76971179 20117:76970979-76971179 chr17 76972138 76972338 201 17:76972138-76972338chr17 76973198 76973398 201 17:76973198-76973398 chr17 76973305 76973505201 17:76973305-76973505 chr17 76975825 76976025 20117:76975825-76976025 chr17 76975857 76976057 201 17:76975857-76976057chr17 76975873 76976073 201 17:76975873-76976073 chr17 76975890 76976090201 17:76975890-76976090 chr17 76975893 76976093 20117:76975893-76976093 chr17 76975900 76976100 201 17:76975900-76976100chr17 76975905 76976105 201 17:76975905-76976105 chr17 76975909 76976109201 17:76975909-76976109 chr17 76975917 76976117 20117:76975917-76976117 chr17 76975929 76976129 201 17:76975929-76976129chr17 76976091 76976291 201 17:76976091-76976291 chr18 25616449 25616649201 18:25616449-25616649 chr18 25625460 25625660 20118:25625460-25625660 chr18 25677093 25677293 201 18:25677093-25677293chr18 25739161 25739361 201 18:25739161-25739361 chr18 25757310 25757510201 18:25757310-25757510 chr18 31158479 31158679 20118:31158479-31158679 chr18 31158496 31158696 201 18:31158496-31158696chr18 31158505 31158705 201 18:31158505-31158705 chr18 31158508 31158708201 18:31158508-31158708 chr18 31158530 31158730 20118:31158530-31158730 chr18 31158635 31158835 201 18:31158635-31158835chr18 31158746 31158946 201 18:31158746-31158946 chr18 31185450 31185650201 18:31185450-31185650 chr18 31185451 31185651 20118:31185451-31185651 chr18 31185458 31185658 201 18:31185458-31185658chr18 31185463 31185663 201 18:31185463-31185663 chr18 31185472 31185672201 18:31185472-31185672 chr18 31185490 31185690 20118:31185490-31185690 chr18 31187471 31187671 201 18:31187471-31187671chr19 39989435 39989635 201 19:39989435-39989635 chr19 39989507 39989707201 19:39989507-39989707 chr19 39989508 39989708 20119:39989508-39989708 chr19 46916741 46916941 201 19:46916741-46916941chr19 51358071 51358271 201 19:51358071-51358271 chr19 51358077 51358277201 19:51358077-51358277 chr19 51358086 51358286 20119:51358086-51358286 chr19 51358091 51358291 201 19:51358091-51358291chr19 51358105 51358305 201 19:51358105-51358305 chr19 51358112 51358312201 19:51358112-51358312 chr19 51358128 51358328 20119:51358128-51358328 chr19 51360547 51360747 201 19:51360547-51360747chr20 3210322 3210522 201 20:3210322-3210522 chr20 3211106 3211306 20120:3211106-3211306 chr20 3218273 3218473 201 20:3218273-3218473 chr203218712 3218912 201 20:3218712-3218912 chr20 3219259 3219459 20120:3219259-3219459 chr20 3219736 3219936 201 20:3219736-3219936 chr205891976 5892176 201 20:5891976-5892176 chr20 5892076 5892276 20120:5892076-5892276 chr20 5896044 5896244 201 20:5896044-5896244 chr2020348665 20348865 201 20:20348665-20348865 chr20 22565001 22565201 20120:22565001-22565201 chr20 22565993 22566193 201 20:22565993-22566193chr21 42839929 42840129 201 21:42839929-42840129 chr21 42840664 42840864201 21:42840664-42840864 chr21 42878431 42878631 20121:42878431-42878631 chr21 42879809 42880009 201 21:42879809-42880009chr21 42879892 42880092 201 21:42879892-42880092 chr21 42879919 42880119201 21:42879919-42880119 chr21 42879941 42880141 20121:42879941-42880141 chr21 42879985 42880185 201 21:42879985-42880185chr21 42879986 42880186 201 21:42879986-42880186 chr21 42902925 42903125201 21:42902925-42903125 chr21 42902943 42903143 20121:42902943-42903143 chrX 49056535 49056735 201 X:49056535-49056735 chrX49056552 49056752 201 X:49056552-49056752 chrX 49056554 49056754 201X:49056554-49056754 chrX 49056558 49056758 201 X:49056558-49056758 chrX49056618 49056818 201 X:49056618-49056818 chrX 66764365 66764565 201X:66764365-66764565 chrX 66764562 66764762 201 X:66764562-66764762 chrX66764886 66765086 201 X:66764886-66765086 chrX 66788631 66788831 201X:66788631-66788831 chr1 202039153 202039152 0 1:202039153-202039152chr1 241206098 241206097 0 1:241206098-241206097 chr2 89530057 895300560 2:89530057-89530056 chr3 193490472 193490471 0 3:193490472-193490471chr5 1548487 1548486 0 5:1548487-1548486 chr5 36521979 36521978 05:36521979-36521978 chr5 39390555 39390554 0 5:39390555-39390554 chr571146894 71146893 0 5:71146894-71146893 chr5 142194123 142194122 05:142194123-142194122 chr5 168573593 168573592 0 5:168573593-168573592chr7 2006579 2006578 0 7:2006579-2006578 chr7 7799018 7799017 07:7799018-7799017 chr7 127841628 127841627 0 7:127841628-127841627 chr7129912398 129912397 0 7:129912398-129912397 chr8 53499560 53499559 08:53499560-53499559 chr8 61990390 61990389 0 8:61990390-61990389 chr869087227 69087226 0 8:69087227-69087226 chr8 73479990 73479989 08:73479990-73479989 chr8 73849054 73849053 0 8:73849054-73849053 chr8133070961 133070960 0 8:133070961-133070960 chr8 140727998 140727997 08:140727998-140727997 chr8 141458926 141458925 0 8:141458926-141458925chr8 141994084 141994083 0 8:141994084-141994083 chr8 142367954142367953 0 8:142367954-142367953 chr8 143395944 143395943 08:143395944-143395943 chr9 36748433 36748432 0 9:36748433-36748432 chr938437314 38437313 0 9:38437314-38437313 chr9 93792388 93792387 09:93792388-93792387 chr9 133769512 133769511 0 9:133769512-133769511chr9 134913164 134913163 0 9:134913164-134913163 chr9 138719304138719303 0 9:138719304-138719303 chr14 100039425 100039424 014:100039425-100039424 chr18 8660098 8660097 0 18:8660098-8660097 chr1814917016 14917015 0 18:14917016-14917015 chr18 25442246 25442245 018:25442246-25442245 chr18 47258089 47258088 0 18:47258089-47258088chr20 20421462 20421461 0 20:20421462-20421461 chr20 21563921 21563920 020:21563921-21563920 chr21 32546326 32546325 0 21:32546326-32546325chr21 46885392 46885391 0 21:46885392-46885391 For the “region_set” and“selection_set” columns, note that “rockermeth” denotes“rockermeth_NEvsAdeno”; “rockermethSegs” denotes“cellDMC_rockermethSegs”; “DMS_GOI” denotes “DMS_genesOfInterest”;“AUC_Δβ_GOI” denotes “AUC_deltaBeta_GenesOfInterest”; “AUC_Δβ_TS”denotes “AUC_deltaBeta_TopSignal”; “P_DEgenes” denotes“Promoter_DEgenes”; “ExpMeth” denotes“ExpMeth_DE_in_PARCB_NE_or_GeneOfInterest”; and “CpG_2020” denotes“CpG_site_DNAmeth_classifierJCI_2020”. meth Peak start_hg19 region_setselection_test state priority_in_set ID f_anno extra_anno chr1 32237823mCRPC_PBMC limma_eBayes 1 32 1 Intergenic chr1 43814069 mCRPC_PBMClimma_eBayes −1 23 2 intron (NM_005373, chr1 151345023 mCRPC_PBMClimma_eBayes −1 2 3 promoter-TSS (NM_001258288) chr1 151810787mCRPC_PBMC limma_eBayes 1 3 4 non-coding (NR_024237, chr2 19561227mCRPC_PBMC limma_eBayes 1 18 5 Intergenic chr2 63283706 mCRPC_PBMClimma_eBayes 1 26 6 non-coding (NR_130153, chr2 177030050 mCRPC_PBMClimma_eBayes 1 24 7 intron (NM_006898, chr2 201450223 mCRPC_PBMClimma_eBayes 1 23 8 promoter-TSS (NM_001159) chr3 50378091 mCRPC_PBMClimma_eBayes 1 11 9 promoter-TSS (NM_170714) chr3 122296269 mCRPC_PBMClimma_eBayes 1 14 10 promoter-TSS (NM_001113523) chr3 124860516mCRPC_PBMC limma_eBayes 1 8 11 intron (NM_024628, chr5 958708 mCRPC_PBMClimma_eBayes −1 22 12 Intergenic chr5 3187966 mCRPC_PBMC limma_eBayes −116 13 Intergenic chr5 180230667 mCRPC_PBMC limma_eBayes 1 20 14promoter-TSS (NM_001364390) chr6 13014771 mCRPC_PBMC limma_eBayes −1 2715 intron (NM_001322314, chr6 15505245 mCRPC_PBMC limma_eBayes −1 1 16intron (NM_004973, chr6 26271093 mCRPC_PBMC limma_eBayes 1 12 17 exon(NM_003534, chr7 73245339 mCRPC_PBMC limma_eBayes −1 3 18 exon(NM_001305, chr7 129425230 mCRPC_PBMC limma_eBayes 1 29 19 Intergenicchr8 56852048 mCRPC_PBMC limma_eBayes 1 13 20 intron (NM_002350, chr899960398 mCRPC_PBMC limma_eBayes 1 10 21 exon (NM_001286841, chr8143625497 mCRPC_PBMC limma_eBayes −1 29 22 3′ UTR chr8 145104006mCRPC_PBMC limma_eBayes 1 2 23 promoter-TSS (NR_158554) chr10 6297648mCRPC_PBMC limma_eBayes −1 21 24 Intergenic chr10 22541895 mCRPC_PBMClimma_eBayes 1 16 25 non-coding (NR_038921, chr11 393838 mCRPC_PBMClimma_eBayes −1 26 26 promoter-TSS (NM_007183) chr11 47416258 mCRPC_PBMClimma_eBayes 1 22 27 Intergenic chr11 63974672 mCRPC_PBMC limma_eBayes 121 28 exon (NM_031471, chr11 165408329 mCRPC_PBMC limma_eBayes 1 30 29exon (NM_153253, chr11 67204996 mCRPC_PBMC limma_eBayes 1 5 30promoter-TSS (NM_005608) chr11 69469526 mCRPC_PBMC limma_eBayes −1 6 31TTS (NM_053056) chr12 7060087 mCRPC_PBMC limma_eBayes 1 25 32promoter-TSS (NM_080549) chr12 53298578 mCRPC_PBMC limma_eBayes −1 17 33promoter-TSS (NM_002273) chr12 95941769 mCRPC_PBMC limma_eBayes 1 19 34promoter-TSS (NM_001278393) chr12 107038917 mCRPC_PBMC limma_eBayes −113 35 intron (NM_213594, chr12 124773568 mCRPC_PBMC limma_eBayes −1 2836 5′ UTR chr12 124950569 mCRPC_PBMC limma_eBayes 1 27 37 exon(NM_001077261, chr16 1128589 mCRPC_PBMC limma_eBayes −1 31 38promoter-TSS (NM_001053) chr17 26732020 mCRPC_PBMC limma_eBayes −1 32 39exon (NM_001242366, chr17 41363402 mCRPC_PBMC limma_eBayes 1 17 40promoter-TSS (NM_001291586) chr17 43318510 mCRPC_PBMC limma_eBayes −1 741 exon (NM_005892, chr17 79251155 mCRPC_PBMC limma_eBayes −1 8 42intron (NM_001037984, chr17 80358729 mCRPC_PBMC limma_eBayes 1 4 43intron (NM_175902, chr17 180847037 mCRPC_PBMC limma_eBayes −1 10 44intron (NM_005993, chr19 2085186 mCRPC_PBMC limma_eBayes 1 31 45 intron(NM_130807, chr19 2588141 mCRPC_PBMC limma_eBayes −1 14 46 intron(NM_052847, chr19 3179264 mCRPC_PBMC limma_eBayes 1 6 47 exon(NM_003775, chr19 10735906 mCRPC_PBMC limma_eBayes −1 12 48 promoter-TSS(NM_001363611) chr19 15568260 mCRPC_PBMC limma_eBayes −1 5 49 exon(NM_001348028, chr19 18872937 mCRPC_PBMC limma_eBayes −1 25 50 intron(NM_001098482, chr19 35940325 mCRPC_PBMC limma_eBayes −1 15 51 intron(NM_005306, chr19 42703509 mCRPC_PBMC limma_eBayes 1 7 52 non-coding(NR_073046, chr22 48027541 mCRPC_PBMC limma_eBayes −1 24 53 promoter-TSS(NR_033377) chr1 2036183 NE_Adeno cellDMC −1 17 1 intron (NM_001033582,chr1 2309984 NE_Adeno cellDMC −1 36 2 non-coding (NR_125361, chr12379650 NE_Adeno cellDMC −1 48 3 Intergenic chr1 9887711 NE_AdenocellDMC −1 6 4 Intergenic chr1 119870187 NE_Adeno cellDMC −1 21 5promoter-TSS (NR_146623) chr1 150122937 NE_Adeno cellDMC −1 18 6 5′ UTRchr1 155034908 NE_Adeno cellDMC −1 30 7 promoter-TSS (NM_182689) chr1156215318 NE_Adeno cellDMC −1 43 8 exon (NM_024897, chr1 205631878NE_Adeno cellDMC 1 14 9 exon (NM_033102, chr1 234666987 NE_Adeno cellDMC1 9 10 non-coding (NR_038426, chr1 234908126 NE_Adeno cellDMC −1 8 11Intergenic chr1 235805303 NE_Adeno cellDMC −1 47 12 intron(NM_001098721, chr1 246939116 NE_Adeno cellDMC 1 1 13 Intergenic chr23281230 NE_Adeno cellDMC −1 37 14 intron (NM_001330530, chr2 10567426NE_Adeno cellDMC 1 11 15 TTS (NM_134421) chr2 11796686 NE_Adeno cellDMC1 3 16 Intergenic chr2 45237589 NE_Adeno cellDMC −1 34 17 Intergenicchr2 121432974 NE_Adeno cellDMC 1 25 18 Intergenic chr2 172952783NE_Adeno cellDMC 1 16 19 3′ UTR chr2 240161519 NE_Adeno cellDMC −1 46 20intron (NM_006037, chr3 134125473 NE_Adeno cellDMC −1 27 21 Intergenicchr3 140813669 NE_Adeno cellDMC −1 5 22 intron (NM_080862, chr3160167217 NE_Adeno cellDMC 1 30 23 promoter-TSS (NM_173084) chr3183891828 NE_Adeno cellDMC 1 18 24 promoter-TSS (NM_001311198) chr4981385 NE_Adeno cellDMC 1 24 25 3′ UTR chr4 1205814 NE_Adeno cellDMC 1 226 non-coding (NR_104331, chr4 7228168 NE_Adeno cellDMC −1 7 27 intron(NM_020777, chr5 92938049 NE_Adeno cellDMC −1 4 28 Intergenic chr5134827036 NE_Adeno cellDMC −1 10 29 Intergenic chr5 147162061 NE_AdenocellDMC −1 42 30 promoter-TSS (NM_001282282) chr5 179588340 NE_AdenocellDMC −1 29 31 intron (NM_175062, chr6 40567217 NE_Adeno cellDMC 1 2632 Intergenic chr6 170449317 NE_Adeno cellDMC −1 41 33 Intergenic chr6170578492 NE_Adeno cellDMC −1 1 34 intron (NR_126021, chr7 214477NE_Adeno cellDMC 1 13 35 intron (NM_020223, chr7 906626 NE_Adeno cellDMC1 6 36 intron (NR_160282, chr7 921951 NE_Adeno cellDMC 1 12 37 intron(NM_015949, chr7 2968216 NE_Adeno cellDMC −1 3 38 intron (NM_001324281,chr7 50628618 NE_Adeno cellDMC −1 25 39 promoter-TSS (NM_001242889) chr7129912387 NE_Adeno cellDMC −1 13 40 intron (NM_001869, chr7 151432920NE_Adeno cellDMC −1 31 41 5′ UTR chr8 73848837 NE_Adeno cellDMC 1 4 42exon (NM_004770, chr8 93114050 NE_Adeno cellDMC −1 24 43 intron(NM_175634, chr10 670687 NE_Adeno cellDMC −1 44 44 intron (NM_014974,chr10 123923781 NE_Adeno cellDMC −1 33 45 intron (NM_001291878, chr1120625892 NE_Adeno cellDMC 1 28 46 intron (NM_004211, chr11 61449637NE_Adeno cellDMC −1 22 47 intron (NM_006133, chr11 62211890 NE_AdenocellDMC −1 20 48 intron (NM_024060, chr12 104852255 NE_Adeno cellDMC −112 49 intron (NM018413, chr12 110172108 NE_Adeno cellDMC −1 39 50non-coding (NR_026661, chr12 125578255 NE_Adeno cellDMC −1 38 51 intron(NM_023928, chr14 91862713 NE_Adeno cellDMC 1 20 52 intron(NM_001080414, chr14 95693684 NE_Adeno cellDMC −1 40 53 intron(NM_024734, chr14 101157815 NE_Adeno cellDMC −1 49 54 Intergenic chr1589921572 NE_Adeno cellDMC 1 15 55 intron (NR_133002, chr15 89959557NE_Adeno cellDMC 1 29 56 intron (NR_160724, chr15 99194331 NE_AdenocellDMC 1 23 57 promoter-TSS (NR_126453) chr16 1195273 NE_Adeno cellDMC−1 45 58 Intergenic chr16 29324459 NE_Adeno cellDMC −1 19 59 intron(NR_002939, chr17 59480574 NE_Adeno cellDMC −1 15 60 intron (NM_005994,chr17 60827102 NE_Adeno cellDMC −1 50 61 intron (NM_001288779, chr1771744333 NE_Adeno cellDMC −1 9 62 TTS (NR_027146) chr17 72350254NE_Adeno cellDMC 1 22 63 exon (NM_153209, chr17 73996145 NE_AdenocellDMC 1 10 64 promoter-TSS (NR_130467).2 chr17 76355046 NE_AdenocellDMC −1 28 65 5′ UTR chr17 78079381 NE_Adeno cellDMC −1 26 66 exon(NM_000152, chr17 79223965 NE_Adeno cellDMC −1 11 67 TTS (NM_138570)chr17 80019426 NE_Adeno cellDMC 1 5 68 exon (NM_022156, chr17 80052807NE_Adeno cellDMC 1 8 69 intron (NM_004104, chr17 80372675 NE_AdenocellDMC 1 17 70 intron (NR_033265, chr17 80832228 NE_Adeno cellDMC 1 1971 intron (NM_005993, chr18 8659409 NE_Adeno cellDMC −1 14 72 Intergenicchr18 13136240 NE_Adeno cellDMC −1 35 73 Intergenic chr19 2540807NE_Adeno cellDMC 1 7 74 intron (NM_052847, chr19 4566300 NE_AdenocellDMC −1 32 75 Intergenic chr19 17790974 NE_Adeno cellDMC 1 27 76intron (NM_001080421, chr20 20432962 NE_Adeno cellDMC −1 2 77 intron(NM_020343, chr21 51589516 NE_Adeno cellDMC −1 23 78 5′ UTR chr2138077158 NE_Adeno cellDMC 1 21 79 intron (NM_009586, chr21 43441927NE_Adeno cellDMC −1 16 80 promoter-TSS (NR_119385) chr1 2036220rockermeth rockermethSegs −1 398 1 promoter-TSS (NM_001033582) chr12036226 rockermeth rockermethSegs −1 400 2 promoter-TSS (NM_001033582)chr1 2036232 rockermeth rockermethSegs −1 397 3 promoter-TSS(NM_001033582) chr1 2036252 rockermeth rockermethSegs −1 399 4promoter-TSS (NM_001033582) chr1 2036395 rockermeth rockermethSegs −1401 5 intron (NM_001033582, chr1 3697617 rockermeth rockermethSegs 1 686 3′ UTR chr1 3697629 rockermeth rockermethSegs 1 63 7 3′ UTR chr13697639 rockermeth rockermethSegs 1 64 8 3′ UTR chr1 3697648 rockermethrockermethSegs 1 65 9 3′ UTR chr1 3697654 rockermeth rockermethSegs 1 6610 exon (NM_020710, chr1 3697667 rockermeth rockermethSegs 1 67 11 exon(NM_020710, chr1 3697692 rockermeth rockermethSegs 1 70 12 exon(NM_020710, chr1 3697702 rockermeth rockermethSegs 1 69 13 exon(NM_020710, chr1 6171653 rockermeth rockermethSegs −1 515 14 intron(NM_015557, chr1 6171833 rockermeth rockermethSegs −1 514 15 exon(NM_015557, chr1 6171838 rockermeth rockermethSegs −1 511 16 exon(NM_015557, chr1 6171845 rockermeth rockermethSegs −1 513 17 exon(NM_015557, chr1 6171867 rockermeth rockermethSegs −1 512 18 exon(NM_015557, chr1 9501648 rockermeth rockermethSegs −1 362 19 Intergenicchr1 10696021 rockermeth rockermethSegs 1 86 20 TTS (NM_001079843) chr110696065 rockermeth rockermethSegs 1 87 21 TTS (NM_001079843) chr118808323 rockermeth rockermethSegs −1 107 22 exon (NM_152375, chr118808343 rockermeth rockermethSegs −1 118 23 exon (NM_152375, chr118808439 rockermeth rockermethSegs −1 120 24 exon (NM_152375, chr118808469 rockermeth rockermethSegs −1 111 25 exon (NM_152375, chr118808546 rockermeth rockermethSegs −1 124 26 exon (NM_152375, chr118808583 rockermeth rockermethSegs −1 113 27 exon (NM_152375, chr118808621 rockermeth rockermethSegs −1 123 28 exon (NM_152375, chr118808832 rockermeth rockermethSegs −1 125 29 exon (NM_152375, chr118808880 rockermeth rockermethSegs −1 119 30 exon (NM_152375, chr118808929 rockermeth rockermethSegs −1 126 31 exon (NM_152375, chr118808938 rockermeth rockermethSegs −1 109 32 exon (NM_152375, chr118808967 rockermeth rockermethSegs −1 110 33 exon (NM_152375, chr118808991 rockermeth rockermethSegs −1 127 34 exon (NM_152375, chr118809009 rockermeth rockermethSegs −1 116 35 exon (NM_152375, chr118809028 rockermeth rockermethSegs −1 115 36 exon (NM_152375, chr118809041 rockermeth rockermethSegs −1 114 37 exon (NM_152375, chr118809052 rockermeth rockermethSegs −1 129 38 exon (NM_152375, chr118809058 rockermeth rockermethSegs −1 121 39 exon (NM_152375, chr118809064 rockermeth rockermethSegs −1 112 40 exon (NM_152375, chr118809102 rockermeth rockermethSegs −1 108 41 exon (NM_152375, chr118809112 rockermeth rockermethSegs −1 128 42 exon (NM_152375, chr118809126 rockermeth rockermethSegs −1 117 43 exon (NM_152375, chr118809494 rockermeth rockermethSegs −1 122 44 exon (NM_152375, chr120141125 rockermeth rockermethSegs −1 266 45 exon (NM_019062, chr120141136 rockermeth rockermethSegs −1 267 46 exon (NM_019062, chr120141322 rockermeth rockermethSegs −1 268 47 exon (NM_019062, chr120141344 rockermeth rockermethSegs −1 269 48 exon (NM_019062, chr120141404 rockermeth rockermethSegs −1 271 49 exon (NM_019062, chr120141442 rockermeth rockermethSegs −1 265 50 exon (NM_019062, chr120141462 rockermeth rockermethSegs −1 270 51 exon (NM_019062, chr122195529 rockermeth rockermethSegs −1 612 52 intron (NM_005529, chr132252163 rockermeth rockermethSegs −1 105 53 Intergenic chr1 32252229rockermeth rockermethSegs −1 104 54 Intergenic chr1 32252239 rockermethrockermethSegs −1 103 55 Intergenic chr1 32252264 rockermethrockermethSegs −1 106 56 Intergenic chr1 32252425 rockermethrockermethSegs −1 102 57 Intergenic chr1 45103348 rockermethrockermethSegs −1 450 58 intron (NM_001319957, chr1 45103390 rockermethrockermethSegs −1 449 59 intron (NM_001319957, chr1 45106491 rockermethrockermethSegs −1 451 60 intron (NM_001319957, chr1 156215343 rockermethrockermethSegs −1 717 61 exon (NM_001272106, chr1 156215371 rockermethrockermethSegs −1 721 62 exon (NM_001272106, chr1 156215401 rockermethrockermethSegs −1 713 63 exon (NM_001272106, chr1 156215416 rockermethrockermethSegs −1 703 64 exon (NM_001272106, chr1 156215430 rockermethrockermethSegs −1 715 65 exon (NM_001272106, chr1 156215445 rockermethrockermethSegs −1 709 66 exon (NM_024897, chr1 156215454 rockermethrockermethSegs −1 711 67 intron (NM_198406, chr1 156215491 rockermethrockermethSegs −1 708 68 intron (NM_198406, chr1 156215506 rockermethrockermethSegs −1 716 69 intron (NM_198406, chr1 156215520 rockermethrockermethSegs −1 710 70 intron (NM_198406, chr1 156215525 rockermethrockermethSegs −1 714 71 intron (NM_198406, chr1 156215530 rockermethrockermethSegs −1 720 72 intron (NM_198406, chr1 156215563 rockermethrockermethSegs −1 706 73 intron (NM_198406, chr1 156215590 rockermethrockermethSegs −1 704 74 exon (NM_024897, chr1 156215601 rockermethrockermethSegs −1 705 75 exon (NM_024897, chr1 156215708 rockermethrockermethSegs −1 719 76 non-coding (NR_073610, chr1 156215720rockermeth rockermethSegs −1 718 77 non-coding (NR_073610, chr1156215726 rockermeth rockermethSegs −1 707 78 non-coding (NR_073610,chr1 156215737 rockermeth rockermethSegs −1 712 79 non-coding(NR_073610, chr1 203259747 rockermeth rockermethSegs −1 402 80Intergenic chr1 203259757 rockermeth rockermethSegs −1 406 81 Intergenicchr1 203259770 rockermeth rockermethSegs −1 403 82 Intergenic chr1203259836 rockermeth rockermethSegs −1 405 83 Intergenic chr1 203259850rockermeth rockermethSegs −1 407 84 Intergenic chr1 203259921 rockermethrockermethSegs −1 404 85 Intergenic chr1 236311219 rockermethrockermethSegs 1 108 86 intron (NM_003272, chr1 236311342 rockermethrockermethSegs 1 109 87 intron (NM_003272, chr1 237129554 rockermethrockermethSegs −1 495 88 Intergenic chr1 237134163 rockermethrockermethSegs −1 501 89 Intergenic chr1 237167480 rockermethrockermethSegs −1 500 90 TTS (NM_001276687) chr1 237194084 rockermethrockermethSegs −1 502 91 Intergenic chr1 237194093 rockermethrockermethSegs −1 499 92 Intergenic chr1 237194098 rockermethrockermethSegs −1 497 93 Intergenic chr1 237195314 rockermethrockermethSegs −1 498 94 Intergenic chr1 237195411 rockermethrockermethSegs −1 496 95 Intergenic chr1 237212336 rockermethrockermethSegs −1 808 96 intron (NM_001035, chr1 237220609 rockermethrockermethSegs −1 795 97 intron (NM_001035, chr1 237220641 rockermethrockermethSegs −1 774 98 intron (NM_001035, chr1 237222098 rockermethrockermethSegs −1 778 99 intron (NM_001035, chr1 237222106 rockermethrockermethSegs −1 802 100 intron (NM_001035, chr1 237235121 rockermethrockermethSegs −1 775 101 intron (NM_001035, chr1 237235204 rockermethrockermethSegs −1 806 102 intron (NM_001035, chr1 237235522 rockermethrockermethSegs −1 791 103 intron (NM_001035, chr1 237235567 rockermethrockermethSegs −1 777 104 intron (NM_001035, chr1 237235607 rockermethrockermethSegs −1 804 105 intron (NM_001035, chr1 237256273 rockermethrockermethSegs −1 805 106 intron (NM_001035, chr1 237256316 rockermethrockermethSegs −1 781 107 intron (NM_001035, chr1 237265786 rockermethrockermethSegs −1 809 108 intron (NM_001035, chr1 237265877 rockermethrockermethSegs −1 783 109 intron (NM_001035, chr1 237267786 rockermethrockermethSegs −1 784 110 intron (NM_001035, chr1 237267812 rockermethrockermethSegs −1 785 111 intron (NM_001035, chr1 237267886 rockermethrockermethSegs −1 790 112 intron (NM_001035, chr1 237306208 rockermethrockermethSegs −1 792 113 intron (NM_001035, chr1 237306260 rockermethrockermethSegs −1 782 114 intron (NM_001035, chr1 237343254 rockermethrockermethSegs −1 779 115 intron (NM_001035, chr1 237359169 rockermethrockermethSegs −1 810 116 intron (NM_001035, chr1 237383690 rockermethrockermethSegs −1 773 117 intron (NM_001035, chr1 237392760 rockermethrockermethSegs −1 799 118 intron (NM_001035, chr1 237408076 rockermethrockermethSegs −1 788 119 intron (NM_001035, chr1 237408091 rockermethrockermethSegs −1 803 120 intron (NM_001035, chr1 237473057 rockermethrockermethSegs −1 776 121 intron (NM_001035, chr1 237473071 rockermethrockermethSegs −1 789 122 intron (NM_001035, chr1 237473091 rockermethrockermethSegs −1 786 123 intron (NM_001035, chr1 237473164 rockermethrockermethSegs −1 798 124 intron (NM_001035, chr1 237538162 rockermethrockermethSegs −1 800 125 intron (NM_001035, chr1 237584276 rockermethrockermethSegs −1 771 126 intron (NM_001035, chr1 237661252 rockermethrockermethSegs −1 793 127 intron (NM_001035, chr1 237661262 rockermethrockermethSegs −1 801 128 intron (NM_001035, chr1 237661322 rockermethrockermethSegs −1 770 129 intron (NM_001035, chr1 237693526 rockermethrockermethSegs −1 787 130 intron (NM_001035, chr1 237693534 rockermethrockermethSegs −1 772 131 intron (NM_001035, chr1 237699930 rockermethrockermethSegs −1 794 132 intron (NM_001035, chr1 237699938 rockermethrockermethSegs −1 780 133 intron (NM_001035, chr1 237699988 rockermethrockermethSegs −1 807 134 intron (NM_001035, chr1 237809365 rockermethrockermethSegs −1 796 135 intron (NM_001035, chr1 237815260 rockermethrockermethSegs −1 797 136 intron (NM_001035, chr1 241402493 rockermethrockermethSegs 1 91 137 intron (NM_001364886, chr1 241402516 rockermethrockermethSegs 1 92 138 intron (NM_001364886, chr2 9248023 rockermethrockermethSegs −1 259 139 Intergenic chr2 9248368 rockermethrockermethSegs −1 258 140 Intergenic chr2 9248435 rockermethrockermethSegs −1 260 141 Intergenic chr2 9248469 rockermethrockermethSegs −1 257 142 Intergenic chr2 25299679 rockermethrockermethSegs −1 591 143 intron (NM_001319099, chr2 25299815 rockermethrockermethSegs −1 590 144 intron (NM_001319099, chr2 25299928 rockermethrockermethSegs −1 589 145 intron (NM_001319099, chr2 43102420 rockermethrockermethSegs 1 97 146 Intergenic chr2 43107259 rockermethrockermethSegs 1 93 147 Intergenic chr2 43107400 rockermethrockermethSegs 1 98 148 Intergenic chr2 43107414 rockermethrockermethSegs 1 96 149 Intergenic chr2 43107438 rockermethrockermethSegs 1 99 150 Intergenic chr2 43107456 rockermethrockermethSegs 1 95 151 Intergenic chr2 43107465 rockermethrockermethSegs 1 94 152 Intergenic chr2 43107514 rockermethrockermethSegs 1 101 153 Intergenic chr2 43107532 rockermethrockermethSegs 1 102 154 Intergenic chr2 43107650 rockermethrockermethSegs 1 100 155 Intergenic chr2 45235684 rockermethrockermethSegs −1 262 156 intron (NM_016932, chr2 45235702 rockermethrockermethSegs −1 263 157 exon (NM_016932, chr2 45235710 rockermethrockermethSegs −1 264 158 exon (NM_016932, chr2 207972376 rockermethrockermethSegs −1 208 159 intron (NR_073108, chr2 207972408 rockermethrockermethSegs −1 207 160 intron (NR_073108, chr2 220509654 rockermethrockermethSegs −1 336 161 Intergenic chr2 220509693 rockermethrockermethSegs −1 339 162 Intergenic chr2 220509705 rockermethrockermethSegs −1 338 163 Intergenic chr2 220509776 rockermethrockermethSegs −1 337 164 Intergenic chr2 220509830 rockermethrockermethSegs −1 335 165 Intergenic chr2 241233035 rockermethrockermethSegs −1 177 166 Intergenic chr2 241233048 rockermethrockermethSegs −1 176 167 Intergenic chr2 241233055 rockermethrockermethSegs −1 174 168 Intergenic chr2 241233084 rockermethrockermethSegs −1 171 169 Intergenic chr2 241233090 rockermethrockermethSegs −1 175 170 Intersenic chr2 241233169 rockermethrockermethSegs −1 172 171 Intergenic chr2 241233214 rockermethrockermethSegs −1 173 172 Intergenic chr3 111431516 rockermethrockermethSegs −1 226 173 intron (NM_001185106, chr3 111431559rockermeth rockermethSegs −1 225 174 intron (NM_001185106, chr4 3309964rockermeth rockermethSegs −1 91 175 Intergenic chr4 3310004 rockermethrockermethSegs −1 90 176 Intergenic chr4 3311787 rockermethrockermethSegs −1 93 177 Intergenic chr4 3311917 rockermethrockermethSegs −1 92 178 Intergenic chr4 7228254 rockermethrockermethSegs −1 88 179 intron (NM_020777, chr4 7228263 rockermethrockermethSegs −1 86 180 intron (NM_020777, chr4 7228304 rockermethrockermethSegs −1 87 181 intron (NM_020777, chr4 7228329 rockermethrockermethSegs −1 89 182 intron (NM_020777, chr4 7326173 rockermethrockermethSegs −1 660 183 intron (NM_020777, chr4 7326188 rockermethrockermethSegs −1 661 184 intron (NM_020777, chr4 7326270 rockermethrockermethSegs −1 659 185 intron (NM_020777, chr4 7326284 rockermethrockermethSegs −1 662 186 intron (NM_020777, chr4 155758143 rockermethrockermethSegs −1 646 187 Intergenic chr4 155763679 rockermethrockermethSegs −1 649 188 Intergenic chr4 155763688 rockermethrockermethSegs −1 647 189 Intergenic chr4 155763695 rockermethrockermethSegs −1 650 190 Intergenic chr4 155812513 rockermethrockermethSegs −1 651 191 Intergenic chr4 155912924 rockermethrockermethSegs −1 639 192 Intergenic chr4 155965520 rockermethrockermethSegs −1 641 193 Intergenic chr4 155965532 rockermethrockermethSegs −1 643 194 Intergenic chr4 155965538 rockermethrockermethSegs −1 644 195 Intergenic chr4 155965544 rockermethrockermethSegs −1 640 196 Intergenic chr4 155965553 rockermethrockermethSegs −1 645 197 Intergenic chr4 155992200 rockermethrockermethSegs −1 648 198 Intergenic chr4 156002533 rockermethrockermethSegs −1 642 199 Intergenic chr5 1003895 rockermethrockermethSegs −1 747 200 Intergenic chr5 1004045 rockermethrockermethSegs −1 742 201 Intergenic chr5 1004051 rockermethrockermethSegs −1 735 202 Intergenic chr5 1004064 rockermethrockermethSegs −1 736 203 Intergenic chr5 1004077 rockermethrockermethSegs −1 738 204 Intergenic chr5 1004089 rockermethrockermethSegs −1 740 205 Intergenic chr5 1004118 rockermethrockermethSegs −1 730 206 Intergenic chr5 1004128 rockermethrockermethSegs −1 731 207 Intergenic chr5 1004135 rockermethrockermethSegs −1 732 208 Intergenic chr5 1004148 rockermethrockermethSegs −1 728 209 Intergenic chr5 1004157 rockermethrockermethSegs −1 729 210 Intergenic chr5 1004184 rockermethrockermethSegs −1 733 211 Intergenic chr5 1004198 rockermethrockermethSegs −1 745 212 Intergenic chr5 1004234 rockermethrockermethSegs −1 739 213 Intergenic chr5 1004243 rockermethrockermethSegs −1 734 214 Intergenic chr5 1004259 rockermethrockermethSegs −1 743 215 Intergenic chr5 1004269 rockermethrockermethSegs −1 748 216 Intergenic chr5 1004288 rockermethrockermethSegs −1 749 217 Intergenic chr5 1004304 rockermethrockermethSegs −1 737 218 Intergenic chr5 1004351 rockermethrockermethSegs −1 746 219 Intergenic chr5 1004357 rockermethrockermethSegs −1 741 220 Intergenic chr5 1004365 rockermethrockermethSegs −1 744 221 Intergenic chr5 134827336 rockermethrockermethSegs −1 216 222 Intergenic chr5 134827353 rockermethrockermethSegs −1 217 223 Intergenic chr5 134827364 rockermethrockermethSegs −1 218 224 Intergenic chr5 134827378 rockermethrockermethSegs −1 219 225 Intergenic chr5 138441347 rockermethrockermethSegs −1 1 226 intron (NM_001037633, chr5 138441377 rockermethrockermethSegs −1 2 227 intron (NM_001037633, chr5 138441561 rockermethrockermethSegs −1 3 228 intron (NM_001037633, chr5 179401802 rockermethrockermethSegs −1 50 229 intron (NM_018434, chr5 179401833 rockermethrockermethSegs −1 54 230 intron (NM_018434, chr5 179401843 rockermethrockermethSegs −1 53 231 intron (NM_018434, chr5 179401853 rockermethrockermethSegs −1 52 232 intron (NM_018434, chr5 179401872 rockermethrockermethSegs −1 51 233 intron (NM_018434, chr5 179588495 rockermethrockermethSegs −1 463 234 intron (NM_175062, chr5 179588504 rockermethrockermethSegs −1 465 235 intron (NM_175062, chr5 179588512 rockermethrockermethSegs −1 464 236 intron (NM_175062, chr5 179588528 rockermethrockermethSegs −1 455 237 intron (NM_175062, chr5 179588550 rockermethrockermethSegs −1 454 238 intron (NM_175062, chr5 179588590 rockermethrockermethSegs −1 457 239 intron (NM_175062, chr5 179588604 rockermethrockermethSegs −1 456 240 intron (NM_175062, chr5 179588617 rockermethrockermethSegs −1 458 241 intron (NM_175062, chr5 179588625 rockermethrockermethSegs −1 459 242 intron (NM_175062, chr5 179588631 rockermethrockermethSegs −1 461 243 intron (NM_175062, chr5 179588672 rockermethrockermethSegs −1 469 244 intron (NM_175062, chr5 179588687 rockermethrockermethSegs −1 466 245 intron (NM_175062, chr5 179588704 rockermethrockermethSegs −1 467 246 intron (NM_175062, chr5 179588719 rockermethrockermethSegs −1 460 247 intron (NM_175062, chr5 179597660 rockermethrockermethSegs −1 468 248 intron (NM_175062, chr5 179597771 rockermethrockermethSegs −1 470 249 intron (NM_175062, chr5 179597812 rockermethrockermethSegs −1 462 250 intron (NM_175062, chr6 64151793 rockermethrockermethSegs −1 769 251 Intergenic chr6 157549787 rockermethrockermethSegs −1 385 252 Intergenic chr6 157549797 rockermethrockermethSegs −1 383 253 Intergenic chr6 157549848 rockermethrockermethSegs −1 384 254 Intergenic chr6 157550494 rockermethrockermethSegs −1 387 255 Intergenic chr6 157550509 rockermethrockermethSegs −1 386 256 Intergenic chr7 1447696 rockermethrockermethSegs −1 64 257 Intergenic chr7 1447734 rockermethrockermethSegs −1 65 258 Intergenic chr7 1447746 rockermethrockermethSegs −1 67 259 Intergenic chr7 1447760 rockermethrockermethSegs −1 69 260 Intergenic chr7 1447774 rockermethrockermethSegs −1 68 261 Intergenic chr7 1447782 rockermethrockermethSegs −1 66 262 Intergenic chr7 2006576 rockermethrockermethSegs −1 203 263 intron (NM_001304523, chr7 2006674 rockermethrockermethSegs −1 202 264 intron (NM_001304523, chr7 2007262 rockermethrockermethSegs −1 201 265 intron (NM_001304523, chr7 2007279 rockermethrockermethSegs −1 204 266 intron (NM_001304523, chr7 2007309 rockermethrockermethSegs −1 206 267 intron (NM_001304523, chr7 2007394 rockermethrockermethSegs −1 205 268 intron (NM_001304523, chr7 2968280 rockermethrockermethSegs −1 35 269 exon (NM_032415, chr7 2968288 rockermethrockermethSegs −1 28 270 exon (NM_032415, chr7 2968314 rockermethrockermethSegs −1 15 271 exon (NM_032415, chr7 2968320 rockermethrockermethSegs −1 32 272 exon (NM_032415, chr7 2968352 rockermethrockermethSegs −1 36 273 intron (NM_001324281, chr7 2968357 rockermethrockermethSegs −1 33 274 intron (NM_001324281, chr7 2968405 rockermethrockermethSegs −1 29 275 intron (NM_001324281, chr7 2968411 rockermethrockermethSegs −1 16 276 intron (NM_001324281, chr7 2968426 rockermethrockermethSegs −1 17 277 intron (NM_001324281, chr7 2968440 rockermethrockermethSegs −1 18 278 intron (NM_001324281, chr7 2968454 rockermethrockermethSegs −1 19 279 intron (NM_001324281, chr7 2968489 rockermethrockermethSegs −1 20 280 intron (NM_001324281, chr7 2968504 rockermethrockermethSegs −1 34 281 intron (NM_001324281, chr7 2968528 rockermethrockermethSegs −1 21 282 intron (NM_001324281, chr7 2968552 rockermethrockermethSegs −1 22 283 intron (NM_001324281, chr7 2968558 rockermethrockermethSegs −1 23 284 intron (NM_001324281, chr7 2968565 rockermethrockermethSegs −1 24 285 intron (NM_001324281, chr7 2968585 rockermethrockermethSegs −1 25 286 intron (NM_001324281, chr7 2968593 rockermethrockermethSegs −1 26 287 intron (NM_001324281, chr7 2968625 rockermethrockermethSegs −1 27 288 intron (NM_001324281, chr7 2968684 rockermethrockermethSegs −1 30 289 intron (NM_001324281, chr7 2968706 rockermethrockermethSegs −1 31 290 intron (NM_001324281, chr7 26667584 rockermethrockermethSegs −1 300 291 Intergenic chr7 26667613 rockermethrockermethSegs −1 303 292 Intergenic chr7 26667674 rockermethrockermethSegs −1 301 293 Intergenic chr7 26667709 rockermethrockermethSegs −1 302 294 Intergenic chr7 35505816 rockermethrockermethSegs −1 701 295 Intergenic chr7 35505825 rockermethrockermethSegs −1 702 296 Intergenic chr7 41086116 rockermethrockermethSegs −1 504 297 Intergenic chr7 41086123 rockermethrockermethSegs −1 503 298 Intergenic chr7 41086140 rockermethrockermethSegs −1 505 299 Intergenic chr7 101622017 rockermethrockermethSegs −1 84 300 intron (NM_001202544, chr7 101622057 rockermethrockermethSegs −1 85 301 intron (NM_001202544, chr7 101622176 rockermethrockermethSegs −1 83 302 intron (NM_001202544, chr7 115992730 rockermethrockermethSegs −1 343 303 Intergenic chr7 115992814 rockermethrockermethSegs −1 341 304 Intergenic chr7 115998982 rockermethrockermethSegs −1 340 305 Intergenic chr7 115999026 rockermethrockermethSegs −1 342 306 Intergenic chr7 115999448 rockermethrockermethSegs −1 345 307 Intergenic chr7 115999464 rockermethrockermethSegs −1 346 308 Intergenic chr7 116099337 rockermethrockermethSegs −1 344 309 Intergenic chr7 150668588 rockermethrockermethSegs −1 452 310 intron (NM_000238, chr7 150669120 rockermethrockermethSegs −1 453 311 intron (NM_000238, chr7 150811991 rockermethrockermethSegs 1 72 312 exon (NM_001308305, chr7 150812075 rockermethrockermethSegs 1 76 313 exon (NM_001308305, chr7 150812111 rockermethrockermethSegs 1 77 314 exon (NM_001308305, chr7 150812201 rockermethrockermethSegs 1 74 315 exon (NM_001308305, chr7 150812215 rockermethrockermethSegs 1 73 316 exon (NM_001308305, chr7 150812398 rockermethrockermethSegs 1 75 317 exon (NM_001308305, chr7 150812660 rockermethrockermethSegs 1 71 318 exon (NM_001308305, chr7 157423275 rockermethrockermethSegs 1 1 319 intron (NM_001308268, chr7 157623246 rockermethrockermethSegs −1 170 320 intron (NM_001308268, chr8 46929775 rockermethrockermethSegs −1 359 321 Intergenic chr8 46935836 rockermethrockermethSegs −1 353 322 Intergenic chr8 46938035 rockermethrockermethSegs −1 354 323 Intergenic chr8 46938044 rockermethrockermethSegs −1 361 324 Intergenic chr8 46938657 rockermethrockermethSegs −1 355 325 Intergenic chr8 46938693 rockermethrockermethSegs −1 356 326 Intergenic chr8 46938702 rockermethrockermethSegs −1 357 327 Intergenic chr8 46940361 rockermethrockermethSegs −1 358 328 Intergenic chr8 46940406 rockermethrockermethSegs −1 360 329 Intergenic chr8 58062363 rockermethrockermethSegs −1 672 330 Intergenic chr8 58062426 rockermethrockermethSegs −1 666 331 Intergenic chr8 58062463 rockermethrockermethSegs −1 670 332 Intergenic chr8 58096948 rockermethrockermethSegs −1 665 333 Intergenic chr8 58115010 rockermethrockermethSegs −1 695 334 Intergenic chr8 58115060 rockermethrockermethSegs −1 686 335 Intergenic chr8 58115154 rockermethrockermethSegs −1 697 336 Intergenic chr8 58115225 rockermethrockermethSegs −1 680 337 Intergenic chr8 58115343 rockermethrockermethSegs −1 663 338 Intergenic chr8 58115362 rockermethrockermethSegs −1 698 339 Intergenic chr8 58122819 rockermethrockermethSegs −1 693 340 Intergenic chr8 58122836 rockermethrockermethSegs −1 676 341 Intergenic chr8 58122848 rockermethrockermethSegs −1 690 342 Intergenic chr8 58122861 rockermethrockermethSegs −1 682 343 Intergenic chr8 58123008 rockermethrockermethSegs −1 684 344 Intergenic chr8 58126620 rockermethrockermethSegs −1 691 345 Intergenic chr8 58126666 rockermethrockermethSegs −1 700 346 Intergenic chr8 58126874 rockermethrockermethSegs −1 675 347 Intergenic chr8 58127096 rockermethrockermethSegs −1 668 348 Intergenic chr8 58127515 rockermethrockermethSegs −1 685 349 Intergenic chr8 58127556 rockermethrockermethSegs −1 664 350 Intergenic chr8 58127613 rockermethrockermethSegs −1 674 351 Intergenic chr8 58130004 rockermethrockermethSegs −1 678 352 promoter-TSS (NR_038235) chr8 58130021rockermeth rockermethSegs −1 699 353 promoter-TSS (NR_038235) chr858130039 rockermeth rockermethSegs −1 677 354 promoter-TSS (NR_038235)chr8 58131654 rockermeth rockermethSegs −1 667 355 non-coding(NR_038235, chr8 58131665 rockermeth rockermethSegs −1 673 356non-coding (NR_038235, chr8 58131710 rockermeth rockermethSegs −1 689357 intron (NR_038235, chr8 58131715 rockermeth rockermethSegs −1 669358 intron (NR_038235, chr8 58131843 rockermeth rockermethSegs −1 687359 intron (NR_038235, chr8 58131870 rockermeth rockermethSegs −1 696360 intron (NR_038235, chr8 58133184 rockermeth rockermethSegs −1 688361 intron (NR_038235, chr8 58133215 rockermeth rockermethSegs −1 671362 intron (NR_038235, chr8 58133315 rockermeth rockermethSegs −1 694363 intron (NR_038235, chr8 58133743 rockermeth rockermethSegs −1 681364 intron (NR_038235, chr8 58171196 rockermeth rockermethSegs −1 692365 Intergenic chr8 58171236 rockermeth rockermethSegs −1 683 366Intergenic chr8 58192020 rockermeth rockermethSegs −1 679 367promoter-TSS (NR_026772) chr8 61777862 rockermeth rockermethSegs −1 165368 exon (NM_001316690, chr8 61821531 rockermeth rockermethSegs −1 162369 Intergenic chr8 61821546 rockermeth rockermethSegs −1 163 370Intergenic chr8 61821578 rockermeth rockermethSegs −1 164 371 Intergenicchr8 73471538 rockermeth rockermethSegs 1 81 372 intron (NM_004770, chr873480053 rockermeth rockermethSegs 1 82 373 exon (NM_004770, chr873551842 rockermeth rockermethSegs 1 80 374 intron (NM_004770, chr873849013 rockermeth rockermethSegs 1 85 375 exon (NM_004770, chr873849032 rockermeth rockermethSegs 1 84 376 exon (NM_004770, chr873849038 rockermeth rockermethSegs 1 83 377 exon (NM_004770, chr873849051 rockermeth rockermethSegs 1 78 378 exon (NM_004770, chr873849060 rockermeth rockermethSegs 1 79 379 exon (NM_004770, chr8104117894 rockermeth rockermethSegs −1 352 380 Intergenic chr8 140929837rockermeth rockermethSegs −1 604 381 intron (NM_001160372, chr8140930939 rockermeth rockermethSegs −1 606 382 intron (NM_001160372,chr8 140931316 rockermeth rockermethSegs −1 605 383 intron(NM_001160372, chr8 142367903 rockermeth rockermethSegs 1 10 384 exon(NM_005293, chr8 142367951 rockermeth rockermethSegs 1 12 385 exon(NM_005293, chr8 142367989 rockermeth rockermethSegs 1 11 386 exon(NM_005293, chr9 117049844 rockermeth rockermethSegs −1 636 387 intron(NM_032888, chr9 117049850 rockermeth rockermethSegs −1 638 388 intron(NM_032888, chr9 117049862 rockermeth rockermethSegs −1 635 389 intron(NM_032888, chr9 117049885 rockermeth rockermethSegs −1 637 390 intron(NM_032888, chr9 127105722 rockermeth rockermethSegs −1 516 391 intron(NM_014397, chr9 127105763 rockermeth rockermethSegs −1 517 392 intron(NM_014397, chr9 129895923 rockermeth rockermethSegs −1 139 393 intron(NM_014636, chr9 136007375 rockermeth rockermethSegs −1 322 394promoter-TSS (NM_001271774) chr9 136007484 rockermeth rockermethSegs −1319 395 promoter-TSS (NM_001271774) chr9 136007594 rockermethrockermethSegs −1 320 396 intron (NM_001042368, chr9 136007599rockermeth rockermethSegs −1 321 397 intron (NM_001042368, chr9136007615 rockermeth rockermethSegs −1 324 398 intron (NM_001042368,chr9 136007712 rockermeth rockermethSegs −1 323 399 intron(NM_001042368, chr9 136324027 rockermeth rockermethSegs −1 519 400intron (NM_139026, chr9 136324037 rockermeth rockermethSegs −1 520 401intron (NM_139026, chr9 136324064 rockermeth rockermethSegs −1 518 402intron (NM_139026, chr9 138688868 rockermeth rockermethSegs −1 654 403Intergenic chr9 138688876 rockermeth rockermethSegs −1 652 404Intergenic chr9 138688902 rockermeth rockermethSegs −1 653 405Intergenic chr9 138688936 rockermeth rockermethSegs −1 656 406Intergenic chr9 138689094 rockermeth rockermethSegs −1 657 407Intergenic chr9 138689107 rockermeth rockermethSegs −1 655 408Intergenic chr9 138689483 rockermeth rockermethSegs −1 658 409Intergenic chr9 138719312 rockermeth rockermethSegs 1 13 410 exon(NM_015447, chr9 138719386 rockermeth rockermethSegs 1 14 411 exon(NM_015447, chr9 139419669 rockermeth rockermethSegs −1 288 412 intron(NM_017617, chr9 139419769 rockermeth rockermethSegs −1 286 413 intron(NM_017617, chr9 139419814 rockermeth rockermethSegs −1 298 414 intron(NM_017617, chr9 139419865 rockermeth rockermethSegs −1 278 415 intron(NM_017617, chr9 139419924 rockermeth rockermethSegs −1 299 416 intron(NM_017617, chr9 139419933 rockermeth rockermethSegs −1 275 417 intron(NM_017617, chr9 139419956 rockermeth rockermethSegs −1 287 418 intron(NM_017617, chr9 139420550 rockermeth rockermethSegs −1 294 419 intron(NM_017617, chr9 139420561 rockermeth rockermethSegs −1 297 420 intron(NM_017617, chr9 139420578 rockermeth rockermethSegs −1 289 421 intron(NM_017617, chr9 139420602 rockermeth rockermethSegs −1 274 422 intron(NM_017617, chr9 139420641 rockermeth rockermethSegs −1 282 423 intron(NM_017617, chr9 139420862 rockermeth rockermethSegs −1 284 424 intron(NM_017617, chr9 139420914 rockermeth rockermethSegs −1 276 425 intron(NM_017617, chr9 139421144 rockermeth rockermethSegs −1 295 426 intron(NM_017617, chr9 139421220 rockermeth rockermethSegs −1 291 427 intron(NM_017617, chr9 139421241 rockermeth rockermethSegs −1 296 428 intron(NM_017617, chr9 139421257 rockermeth rockermethSegs −1 280 429 intron(NM_017617, chr9 139421267 rockermeth rockermethSegs −1 293 430 intron(NM_017617, chr9 139421321 rockermeth rockermethSegs −1 285 431 intron(NM_017617, chr9 139421342 rockermeth rockermethSegs −1 292 432 intron(NM_017617, chr9 139421362 rockermeth rockermethSegs −1 290 433 intron(NM_017617, chr9 139422178 rockermeth rockermethSegs −1 272 434 intron(NM_017617, chr9 139422203 rockermeth rockermethSegs −1 279 435 intron(NM_017617, chr9 139422218 rockermeth rockermethSegs −1 277 436 intron(NM_017617, chr9 139422266 rockermeth rockermethSegs −1 281 437 intron(NM_017617, chr9 139422290 rockermeth rockermethSegs −1 273 438 intron(NM_017617, chr9 139422314 rockermeth rockermethSegs −1 283 439 intron(NM_017617, chr10 23976532 rockermeth rockermethSegs −1 623 440Intergenic chr10 23976581 rockermeth rockermethSegs −1 624 441Intergenic chr10 72489844 rockermeth rockermethSegs −1 13 442 intron(NM_139155, chr10 72489870 rockermeth rockermethSegs −1 9 443 exon(NM_080722, chr10 72489889 rockermeth rockermethSegs −1 10 444 exon(NM_080722, chr10 72489949 rockermeth rockermethSegs −1 12 445 exon(NM_080722, chr10 72489967 rockermeth rockermethSegs −1 11 446 exon(NM_080722, chr10 72489983 rockermeth rockermethSegs −1 14 447 exon(NM_080722, chr10 119590052 rockermeth rockermethSegs −1 325 448Intergenic chr10 134562610 rockermeth rockermethSegs −1 390 449 intron(NM_005539, chr10 134563052 rockermeth rockermethSegs −1 388 450 exon(NM_001321042, chr10 134563060 rockermeth rockermethSegs −1 393 451 exon(NM_001321042, chr10 134563098 rockermeth rockermethSegs −1 391 452 exon(NM_001321042, chr10 134563109 rockermeth rockermethSegs −1 394 453 exon(NM_001321042, chr10 134563144 rockermeth rockermethSegs −1 395 454intron (NM_005539, chr10 134563149 rockermeth rockermethSegs −1 392 455intron (NM_005539, chr10 134563186 rockermeth rockermethSegs −1 396 456intron (NM_005539, chr10 134563199 rockermeth rockermethSegs −1 389 457intron (NM_005539, chr11 2495501 rockermeth rockermethSegs −1 601 458intron (NM_181798, chr11 2495543 rockermeth rockermethSegs −1 602 459intron (NM_181798, chr11 2495585 rockermeth rockermethSegs −1 603 460intron (NM_181798, chr11 2495609 rockermeth rockermethSegs −1 600 461intron (NM_181798, chr11 68967954 rockermeth rockermethSegs −1 565 462Intergenic chr11 68967994 rockermeth rockermethSegs −1 563 463Intergenic chr11 68968016 rockermeth rockermethSegs −1 562 464Intergenic chr11 68968032 rockermeth rockermethSegs −1 564 465Intergenic chr11 68968042 rockermeth rockermethSegs −1 569 466Intergenic chr11 68968141 rockermeth rockermethSegs −1 566 467Intergenic chr11 68968151 rockermeth rockermethSegs −1 567 468Intergenic chr11 68968156 rockermeth rockermethSegs −1 568 469Intergenic chr11 68968182 rockermeth rockermethSegs −1 561 470Intergenic chr11 68968214 rockermeth rockermethSegs −1 570 471Intergenic chr11 68968240 rockermeth rockermethSegs −1 571 472Intergenic chr11 68968267 rockermeth rockermethSegs −1 560 473Intergenic chr11 70851529 rockermeth rockermethSegs −1 316 474 intron(NM_012309, chr11 70851574 rockermeth rockermethSegs −1 314 475 intron(NM_012309, chr11 70851603 rockermeth rockermethSegs −1 309 476 intron(NM_012309, chr11 70851619 rockermeth rockermethSegs −1 307 477 intron(NM_012309, chr11 70851638 rockermeth rockermethSegs −1 312 478 intron(NM_012309, chr11 70851713 rockermeth rockermethSegs −1 306 479 intron(NM_012309, chr11 70851722 rockermeth rockermethSegs −1 317 480 intron(NM_012309, chr11 70851730 rockermeth rockermethSegs −1 310 481 intron(NM_012309, chr11 70851827 rockermeth rockermethSegs −1 311 482 intron(NM_012309, chr11 70851836 rockermeth rockermethSegs −1 313 483 intron(NM_012309, chr11 70851859 rockermeth rockermethSegs −1 308 484 intron(NM_012309, chr11 70851868 rockermeth rockermethSegs −1 304 485 intron(NM_012309, chr11 70851883 rockermeth rockermethSegs −1 318 486 intron(NM_012309, chr11 70851889 rockermeth rockermethSegs −1 305 487 intron(NM_012309, chr11 70851914 rockermeth rockermethSegs −1 315 488 intron(NM_012309, chr11 70862301 rockermeth rockermethSegs −1 166 489 intron(NM_012309, chr11 70862379 rockermeth rockermethSegs −1 168 490 intron(NM_012309, chr11 70862397 rockermeth rockermethSegs −1 167 491 intron(NM_012309, chr11 70862405 rockermeth rockermethSegs −1 169 492 intron(NM_012309, chr11 111265961 rockermeth rockermethSegs −1 382 493Intergenic chr11 111266000 rockermeth rockermethSegs −1 378 494Intergenic chr11 111266014 rockermeth rockermethSegs −1 381 495Intergenic chr11 111266031 rockermeth rockermethSegs −1 380 496Intergenic chr11 111266119 rockermeth rockermethSegs −1 379 497Intergenic chr11 115829517 rockermeth rockermethSegs −1 328 498Intergenic chr11 115829550 rockermeth rockermethSegs −1 329 499Intergenic chr11 115830020 rockermeth rockermethSegs −1 327 500Intergenic chr11 115830200 rockermeth rockermethSegs −1 326 501Intergenic chr11 133902554 rockermeth rockermethSegs −1 580 502non-coding (NR_027276, chr11 133902596 rockermeth rockermethSegs −1 587503 non-coding (NR_027276, chr11 133902615 rockermeth rockermethSegs −1588 504 non-coding (NR_027276, chr11 133902626 rockermeth rockermethSegs−1 585 505 non-coding (NR_027276, chr11 133902656 rockermethrockermethSegs −1 582 506 non-coding (NR_027276, chr11 133902669rockermeth rockermethSegs −1 583 507 non-coding (NR_027276, chr11133902689 rockermeth rockermethSegs −1 581 508 non-coding (NR_027276,chr11 133902724 rockermeth rockermethSegs −1 579 509 non-coding(NR_027276. chr11 133902737 rockermeth rockermethSegs −1 584 510non-coding (NR_027276, chr11 133902744 rockermeth rockermethSegs −1 586511 non-coding (NR_027276, chr11 133902766 rockermeth rockermethSegs −1578 512 intron (NR_027276, chr12 1957456 rockermeth rockermethSegs −1508 513 intron (NM_172364, chr12 1957466 rockermeth rockermethSegs −1507 514 intron (NM_172364, chr12 1957486 rockermeth rockermethSegs −1506 515 intron (NM_172364, chr12 1957501 rockermeth rockermethSegs −1510 516 intron (NM_172364, chr12 1957566 rockermeth rockermethSegs −1509 517 intron (NM_172364, chr12 34488345 rockermeth rockermethSegs 1107 518 Intergenic chr12 34488352 rockermeth rockermethSegs 1 106 519Intergenic chr12 66111480 rockermeth rockermethSegs −1 350 520Intergenic chr12 66111548 rockermeth rockermethSegs −1 348 521Intergenic chr12 66114657 rockermeth rockermethSegs −1 347 522Intergenic chr12 66114687 rockermeth rockermethSegs −1 351 523Intergenic chr12 66114695 rockermeth rockermethSegs −1 349 524Intergenic chr12 66262212 rockermeth rockermethSegs −1 131 525 intron(NR_158984, chr12 66262228 rockermeth rockermethSegs −1 130 526 intron(NR_158984, chr12 115109512 rockermeth rockermethSegs 1 5 527 3′ UTRchr12 115109529 rockermeth rockermethSegs 1 7 528 3′ UTR chr12 115109718rockermeth rockermethSegs 1 6 529 exon (NM_005996, chr12 115109960rockermeth rockermethSegs 1 2 530 exon (NM_005996, chr12 115112024rockermeth rockermethSegs 1 4 531 exon (NM_005996, chr12 115112037rockermeth rockermethSegs 1 3 532 exon (NM_005996, chr12 124947867rockermeth rockermethSegs −1 143 533 intron (NM_001206654, chr12124948139 rockermeth rockermethSegs −1 144 534 intron (NM_001206654,chr13 114523664 rockermeth rockermethSegs −1 559 535 3′ UTR chr13114523669 rockermeth rockermethSegs −1 549 536 3′ UTR chr13 114523717rockermeth rockermethSegs −1 543 537 3′ UTR chr13 114523760 rockermethrockermethSegs −1 536 538 3′ UTR chr13 114523787 rockermethrockermethSegs −1 537 539 3′ UTR chr13 114523796 rockermethrockermethSegs −1 533 540 3′ UTR chr13 114523819 rockermethrockermethSegs −1 538 541 3′ UTR chr13 114523826 rockermethrockermethSegs −1 544 542 3′ UTR chr13 114523875 rockermethrockermethSegs −1 550 543 exon (NM_000820, chr13 114523883 rockermethrockermethSegs −1 535 544 exon (NM_000820, chr13 114523896 rockermethrockermethSegs −1 531 545 exon (NM_000820, chr13 114523904 rockermethrockermethSegs −1 546 546 exon (NM_000820, chr13 114523923 rockermethrockermethSegs −1 532 547 exon (NM_000820, chr13 114523948 rockermethrockermethSegs −1 530 548 exon (NM_000820, chr13 114523958 rockermethrockermethSegs −1 542 549 exon (NM_000820, chr13 114523970 rockermethrockermethSegs −1 534 550 exon (NM_000820, chr13 114523982 rockermethrockermethSegs −1 556 551 exon (NM_000820, chr13 114523996 rockermethrockermethSegs −1 539 552 intron (NM_000820, chr13 114524029 rockermethrockermethSegs −1 548 553 intron (NM_000820, chr13 114524093 rockermethrockermethSegs −1 529 554 intron (NM_000820, chr13 114524130 rockermethrockermethSegs −1 558 555 intron (NM_000820, chr13 114524137 rockermethrockermethSegs −1 553 556 intron (NM_000820, chr13 114524149 rockermethrockermethSegs −1 557 557 intron (NM_000820, chr13 114524157 rockermethrockermethSegs −1 554 558 intron (NM_000820, chr13 114524420 rockermethrockermethSegs −1 540 559 intron (NM_000820, chr13 114524429 rockermethrockermethSegs −1 541 560 intron (NM_000820, chr13 114524439 rockermethrockermethSegs −1 552 561 intron (NM_000820, chr13 114524473 rockermethrockermethSegs −1 547 562 intron (NM_000820, chr3 114524509 rockermethrockermethSegs −1 551 563 intron (NM_000820, chr13 114524517 rockermethrockermethSegs −1 545 564 intron (NM_000820, chr13 114524583 rockermethrockermethSegs −1 555 565 intron (NM_000820, chr14 20684518 rockermethrockermethSegs −1 527 566 Intergenic chr14 20684528 rockermethrockermethSegs −1 528 567 Intergenic chr14 76957115 rockermethrockermethSegs −1 153 568 intron (NM_004452, chr14 76957138 rockermethrockermethSegs −1 154 569 intron (NM_004452, chr14 76957152 rockermethrockermethSegs −1 151 570 intron (NM_004452, chr14 76957199 rockermethrockermethSegs −1 152 571 intron (NM_004452, chr14 93423461 rockermethrockermethSegs −1 186 572 intron (NM_001142593, chr14 93423503rockermeth rockermethSegs −1 189 573 intron (NM_001142593, chr1493423558 rockermeth rockermethSegs −1 192 574 intron (NM_001142593,chr14 93425210 rockermeth rockermethSegs −1 199 575 intron(NM_001142593, chr14 93425284 rockermeth rockermethSegs −1 187 576intron (NM_001142593, chr14 93425331 rockermeth rockermethSegs −1 200577 intron (NM_001142593, chr14 93425520 rockermeth rockermethSegs −1195 578 intron (NM_001142593, chr14 93425529 rockermeth rockermethSegs−1 180 579 intron (NM_001142593, chr14 93425655 rockermethrockermethSegs −1 178 580 intron (NM_001142593, chr14 93425687rockermeth rockermethSegs −1 194 581 intron (NM_001142593, chr1493425735 rockermeth rockermethSegs −1 181 582 intron (NM_001142593,chr14 93425741 rockermeth rockermethSegs −1 188 583 intron(NM_001142593, chr14 93426221 rockermeth rockermethSegs −1 191 584intron (NM_001142593, chr14 93426229 rockermeth rockermethSegs −1 184585 intron (NM_001142593, chr14 93426247 rockermeth rockermethSegs −1193 586 intron (NM_001142593, chr14 93426257 rockermeth rockermethSegs−1 190 587 intron (NM_001142593, chr14 93426336 rockermethrockermethSegs −1 182 588 intron (NM_001142593, chr14 93426381rockermeth rockermethSegs −1 198 589 intron (NM_001142593, chr1493426456 rockermeth rockermethSegs −1 179 590 intron (NM_001142593,chr14 93426481 rockermeth rockermethSegs −1 185 591 intron(NM_001142593, chr14 93426499 rockermeth rockermethSegs −1 183 592intron (NM_001142593, chr14 93426875 rockermeth rockermethSegs −1 196593 intron (NM_001142593, chr14 93426916 rockermeth rockermethSegs −1197 594 intron (NM_001142593, chr14 101158277 rockermeth rockermethSegs−1 525 595 Intergenic chr14 101158294 rockermeth rockermethSegs −1 524596 Intergenic chr14 101159404 rockermeth rockermethSegs −1 523 597Intergenic chr14 101159430 rockermeth rockermethSegs −1 522 598Intergenic chr14 101159551 rockermeth rockermethSegs −1 521 599Intergenic chr14 101250153 rockermeth rockermethSegs −1 59 600Intergenic chr14 101250165 rockermeth rockermethSegs −1 58 601Intergenic chr14 101250240 rockermeth rockermethSegs −1 56 602Intergenic chr14 101250254 rockermeth rockermethSegs −1 57 603Intergenic chr14 101250279 rockermeth rockermethSegs −1 55 604Intergenic chr14 101640895 rockermeth rockermethSegs −1 40 605Intergenic chr14 101640910 rockermeth rockermethSegs −1 37 606Intergenic chr14 101640942 rockermeth rockermethSegs −1 38 607Intergenic chr14 101640959 rockermeth rockermethSegs −1 39 608Intergenic chr14 105347685 rockermeth rockermethSegs −1 95 609 intron(NM_001112726, chr14 105347700 rockermeth rockermethSegs −1 99 610intron (NM_001112726, chr14 105347712 rockermeth rockermethSegs −1 96611 intron (NM_001112726, chr14 105347802 rockermeth rockermethSegs −1101 612 intron (NM_001112726, chr14 105347810 rockermeth rockermethSegs−1 94 613 intron (NM_001112726, chr14 105347834 rockermethrockermethSegs −1 100 614 intron (NM_001112726, chr14 105347851rockermeth rockermethSegs −1 97 615 intron (NM_001112726, chr14105347961 rockermeth rockermethSegs −1 98 616 intron (NM_001112726,chr15 22559959 rockermeth rockermethSegs −1 753 617 intron (NR_033735,chr15 22559966 rockermeth rockermethSegs −1 752 618 intron (NR_033735,chr15 22567152 rockermeth rockermethSegs −1 755 619 non-coding(NR_033735, chr15 22567172 rockermeth rockermethSegs −1 750 620non-coding (NR_033735, chr15 22571751 rockermeth rockermethSegs −1 757621 TTS (NR_033735) chr15 22571783 rockermeth rockermethSegs −1 756 622TTS (NR_033735) chr15 22581845 rockermeth rockermethSegs −1 754 623Intergenic chr15 22581981 rockermeth rockermethSegs −1 751 624Intergenic chr15 74521143 rockermeth rockermethSegs −1 232 625Intergenic chr15 74521156 rockermeth rockermethSegs −1 230 626Intergenic chr15 74521297 rockermeth rockermethSegs −1 231 627Intergenic chr15 74521344 rockermeth rockermethSegs −1 227 628Intergenic chr15 74521357 rockermeth rockermethSegs −1 228 629Intergenic chr15 74521364 rockermeth rockermethSegs −1 229 630Intergenic chr15 94613752 rockermeth rockermethSegs −1 330 631 intron(NR_120320, chr15 94613766 rockermeth rockermethSegs −1 334 632 intron(NR_120320, chr15 94613787 rockermeth rockermethSegs −1 333 633 intron(NR_120320, chr15 94613823 rockermeth rockermethSegs −1 331 634 intron(NR_120320, chr15 94613901 rockermeth rockermethSegs −1 332 635 intron(NR_120320, chr17 915606 rockermeth rockermethSegs −1 432 636 intron(NM_001256847, chr17 915643 rockermeth rockermethSegs −1 429 637 intron(NM_001256847, chr17 915806 rockermeth rockermethSegs −1 428 638 intron(NM_001256847, chr17 915890 rockermeth rockermethSegs −1 430 639 intron(NM_001256847, chr17 915912 rockermeth rockermethSegs −1 431 640 intron(NM_001256847, chr17 7010397 rockermeth rockermethSegs −1 135 641 exon(NM_001201352, chr17 7010445 rockermeth rockermethSegs −1 132 642 exon(NM_001201352, chr17 7010504 rockermeth rockermethSegs −1 138 643 intron(NM_001181, chr17 7010533 rockermeth rockermethSegs −1 136 644 intron(NM_001181, chr17 7010548 rockermeth rockermethSegs −1 134 645 exon(NM_001201352, chr17 7010630 rockermeth rockermethSegs −1 137 646 exon(NM_001201352, chr17 7010663 rockermeth rockermethSegs −1 133 647 intron(NM_001181, chr17 10728383 rockermeth rockermethSegs −1 425 648 3′ UTRchr17 10740512 rockermeth rockermethSegs −1 427 649 intron(NM_001101387, chr17 10740558 rockermeth rockermethSegs −1 422 650intron (NM_001101387, chr17 10740569 rockermeth rockermethSegs −1 423651 intron (NM_001101387, chr17 10740581 rockermeth rockermethSegs −1424 652 intron (NM_001101387, chr17 10740595 rockermeth rockermethSegs−1 426 653 intron (NM_001101387, chr17 17677711 rockermethrockermethSegs 1 89 654 intron (NM_030665, chr17 17677757 rockermethrockermethSegs 1 88 655 intron (NM_030665, chr17 17677887 rockermethrockermethSegs 1 90 656 intron (NM_030665, chr17 21286388 rockermethrockermethSegs −1 599 657 intron (NM_021012, chr17 21286444 rockermethrockermethSegs −1 592 658 intron (NM_021012, chr17 21286486 rockermethrockermethSegs −1 598 659 intron (NM_021012, chr17 21286510 rockermethrockermethSegs −1 593 660 intron (NM_021012, chr17 21286534 rockermethrockermethSegs −1 594 661 intron (NM_021012, chr17 21286708 rockermethrockermethSegs −1 595 662 intron (NM_021012, chr17 21286741 rockermethrockermethSegs −1 596 663 intron (NM_021012, chr17 21286747 rockermethrockermethSegs −1 597 664 intron (NM_021012, chr17 28299552 rockermethrockermethSegs −1 45 665 intron (NR_026738, chr17 28299565 rockermethrockermethSegs −1 44 666 intron (NR_026738, chr17 28299571 rockermethrockermethSegs −1 42 667 intron (NR_026738, chr17 28299598 rockermethrockermethSegs −1 43 668 intron (NR_026738, chr17 28299697 rockermethrockermethSegs −1 41 669 intron (NR_026738, chr17 71715903 rockermethrockermethSegs −1 762 670 Intergenic chr17 71715940 rockermethrockermethSegs −1 761 671 Intergenic chr17 71715947 rockermethrockermethSegs −1 760 672 Intergenic chr17 71715958 rockermethrockermethSegs −1 758 673 Intergenic chr17 71716005 rockermethrockermethSegs −1 759 674 Intergenic chr17 71743873 rockermethrockermethSegs −1 224 675 intron (NM_001278587, chr17 71744668rockermeth rockermethSegs −1 220 676 TTS (NR_027146) chr17 71744685rockermeth rockermethSegs −1 223 677 TTS (NR_027146) chr17 71744723rockermeth rockermethSegs −1 221 678 TTS (NR_027146) chr17 71744739rockermeth rockermethSegs −1 222 679 TTS (NR_027146) chr17 78079606rockermeth rockermethSegs −1 607 680 exon (NM_000152, chr17 78079613rockermeth rockermethSegs −1 610 681 exon (NM_000152, chr17 78079629rockermeth rockermethSegs −1 608 682 exon (NM_000152, chr17 78079641rockermeth rockermethSegs −1 609 683 exon (NM_000152, chr17 78079653rockermeth rockermethSegs −1 611 684 exon (NM_000152, chr17 78395359rockermeth rockermethSegs −1 722 685 intron (NR_148041, chr17 78395376rockermeth rockermethSegs −1 723 686 intron (NR_148041, chr17 80314127rockermeth rockermethSegs 1 8 687 Intergenic chr17 80314154 rockermethrockermethSegs 1 9 688 Intergenic chr17 80914812 rockermethrockermethSegs −1 626 689 intron (NR_135465, chr17 80915007 rockermethrockermethSegs −1 632 690 intron (NR_135465, chr17 80915042 rockermethrockermethSegs −1 633 691 intron (NR_135465, chr17 80915160 rockermethrockermethSegs −1 628 692 intron (NR_135465, chr17 80915190 rockermethrockermethSegs −1 634 693 intron (NR_135465, chr17 80915238 rockermethrockermethSegs −1 627 694 exon (NM_001009905, chr17 80915248 rockermethrockermethSegs −1 630 695 exon (NM_001009905, chr17 80915270 rockermethrockermethSegs −1 631 696 exon (NM_001009905, chr17 80915289 rockermethrockermethSegs −1 629 697 exon (NM_001009905, chr17 80915308 rockermethrockermethSegs −1 625 698 exon (NM_001009905, chr18 8659649 rockermethrockermethSegs −1 75 699 Intergenic chr18 24348426 rockermethrockermethSegs −1 622 700 Intergenic chr18 25366256 rockermethrockermethSegs −1 215 701 Intergenic chr18 25366262 rockermethrockermethSegs −1 209 702 Intergenic chr18 25366300 rockermethrockermethSegs −1 212 703 Intergenic chr18 25366309 rockermethrockermethSegs −1 214 704 Intergenic chr18 25442175 rockermethrockermethSegs −1 213 705 Intergenic chr18 25442224 rockermethrockermethSegs −1 210 706 Intergenic chr18 25442243 rockermethrockermethSegs −1 211 707 Intergenic chr18 68166868 rockermethrockermethSegs −1 77 708 Intergenic chr18 68166878 rockermethrockermethSegs −1 76 709 Intergenic chr18 77320496 rockermethrockermethSegs −1 475 710 Intergenic chr18 77320538 rockermethrockermethSegs −1 471 711 Intergenic chr18 77320583 rockermethrockermethSegs −1 476 712 Intergenic chr18 77320593 rockermethrockermethSegs −1 473 713 Intergenic chr18 77320606 rockermethrockermethSegs −1 474 714 Intergenic chr18 77320672 rockermethrockermethSegs −1 477 715 Intergenic chr18 77320695 rockermethrockermethSegs −1 478 716 Intergenic chr18 77320711 rockermethrockermethSegs −1 472 717 Intergenic chr18 77320739 rockermethrockermethSegs −1 479 718 Intergenic chr19 883734 rockermethrockermethSegs −1 368 719 intron (NM_005481, chr19 883775 rockermethrockermethSegs −1 377 720 intron (NM_005481, chr19 883830 rockermethrockermethSegs −1 367 721 intron (NM_005481, chr19 883873 rockermethrockermethSegs −1 365 722 intron (NM_005481, chr19 883885 rockermethrockermethSegs −1 373 723 intron (NM_005481, chr19 883994 rockermethrockermethSegs −1 370 724 intron (NM_005481, chr19 884032 rockermethrockermethSegs −1 374 725 intron (NM_005481, chr19 884042 rockermethrockermethSegs −1 369 726 intron (NM_005481, chr19 884057 rockermethrockermethSegs −1 375 727 intron (NM_005481, chr19 884140 rockermethrockermethSegs −1 364 728 intron (NM_005481, chr19 884147 rockermethrockermethSegs −1 371 729 intron (NM_005481, chr19 884172 rockermethrockermethSegs −1 372 730 intron (NM_005481, chr19 884233 rockermethrockermethSegs −1 376 731 intron (NM_005481, chr19 884267 rockermethrockermethSegs −1 363 732 intron (NM_005481, chr19 884346 rockermethrockermethSegs −1 366 733 intron (NM_005481, chr19 2299058 rockermethrockermethSegs −1 82 734 intron (NM_001101391, chr19 2299180 rockermethrockermethSegs −1 78 735 intron (NM_001101391, chr19 2299218 rockermethrockermethSegs −1 81 736 intron (NM_001101391, chr19 2299353 rockermethrockermethSegs −1 79 737 intron (NM_001101391, chr19 2299390 rockermethrockermethSegs −1 80 738 intron (NM_001101391, chr19 4566603 rockermethrockermethSegs −1 49 739 Intergenic chr19 4566636 rockermethrockermethSegs −1 46 740 Intergenic chr19 4566642 rockermethrockermethSegs −1 47 741 Intergenic chr19 4566653 rockermethrockermethSegs −1 48 742 Intergenic chr19 9994121 rockermethrockermethSegs −1 149 743 intron (NM_058164, chr19 9994137 rockermethrockermethSegs −1 145 744 intron (NM_058164, chr19 9994208 rockermethrockermethSegs −1 146 745 intron (NM_058164, chr19 9994219 rockermethrockermethSegs −1 147 746 intron (NM_058164, chr19 9994333 rockermethrockermethSegs −1 148 747 intron (NM_058164, chr19 9994349 rockermethrockermethSegs −1 150 748 intron (NM_058164, chr19 13108021 rockermethrockermethSegs 1 104 749 intron (NM_001365982, chr19 13108640 rockermethrockermethSegs 1 105 750 intron (NM_001365982, chr19 13112778 rockermethrockermethSegs 1 103 751 intron (NM_001365982, chr19 13616660 rockermethrockermethSegs 1 56 752 intron (NM_001127222, chr19 13616810 rockermethrockermethSegs 1 38 753 exon (NM_001127221, chr19 13616818 rockermethrockermethSegs 1 24 754 exon (NM_001127221, chr19 13616834 rockermethrockermethSegs 1 34 755 exon (NM_001127221, chr19 13616868 rockermethrockermethSegs 1 39 756 exon (NM_001127221, chr19 13616879 rockermethrockermethSegs 1 57 757 exon (NM_001127221, chr19 13616906 rockermethrockermethSegs 1 61 758 exon (NM_001127221, chr19 13616911 rockermethrockermethSegs 1 60 759 exon (NM_001127221, chr19 13617010 rockermethrockermethSegs 1 45 760 exon (NM_001127221, chr19 13617018 rockermethrockermethSegs 1 20 761 exon (NM_001127221, chr19 13617024 rockermethrockermethSegs 1 43 762 exon (NM_001127221, chr19 13617029 rockermethrockermethSegs 1 28 763 exon (NM_001127221, chr19 13617058 rockermethrockermethSegs 1 47 764 5′ UTR chr19 13617065 rockermeth rockermethSegs1 48 765 5′ UTR chr19 13617070 rockermeth rockermethSegs 1 40 766 5′ UTRchr19 13617082 rockermeth rockermethSegs 1 27 767 5′ UTR chr19 13617090rockermeth rockermethSegs 1 25 768 5′ UTR chr19 13617128 rockermethrockermethSegs 1 51 769 5′ UTR chr19 13617140 rockermeth rockermethSegs1 33 770 5′ UTR chr19 13617157 rockermeth rockermethSegs 1 29 771 5′ UTRchr19 13617163 rockermeth rockermethSegs 1 30 772 5′ UTR chr19 13617169rockermeth rockermethSegs 1 41 773 5′ UTR chr19 13617176 rockermethrockermethSegs 1 21 774 promoter-TSS (NM_001127221) chr19 13617194rockermeth rockermethSegs 1 22 775 promoter-TSS (NM_001127221) chr1913617208 rockermeth rockermethSegs 1 26 776 promoter-TSS (NM_001127221)chr19 13617218 rockermeth rockermethSegs 1 31 777 promoter-TSS(NM_001127221) chr19 13617233 rockermeth rockermethSegs 1 50 778promoter-TSS (NM_001127221) chr19 13617241 rockermeth rockermethSegs 118 779 promoter-TSS (NM_001127221) chr19 13617250 rockermethrockermethSegs 1 55 780 promoter-TSS (NM_001127221) chr19 13617265rockermeth rockermethSegs 1 37 781 promoter-TSS (NM_001127221) chr1913617288 rockermeth rockermethSegs 1 42 782 promoter-TSS (NM_001127221)chr19 13617302 rockermeth rockermethSegs 1 53 783 promoter-TSS(NM_001127221) chr19 13617315 rockermeth rockermethSegs 1 58 784promoter-TSS (NM_001127221) chr19 13617321 rockermeth rockermethSegs 154 785 promoter-TSS (NM_001127221) chr19 13617328 rockermethrockermethSegs 1 46 786 promoter-TSS (NM_001127221) chr19 13617336rockermeth rockermethSegs 1 62 787 promoter-TSS (NM_001127221) chr1913617364 rockermeth rockermethSegs 1 23 788 promoter-TSS (NM_001127221)chr19 13617380 rockermeth rockermethSegs 1 17 789 promoter-TSS(NM_001127221) chr19 13617419 rockermeth rockermethSegs 1 19 790promoter-TSS (NM_001127221) chr19 13617465 rockermeth rockermethSegs 135 791 promoter-TSS (NM_001127221) chr19 13617483 rockermethrockermethSegs 1 32 792 promoter-TSS (NM_001127221) chr19 13617503rockermeth rockermethSegs 1 15 793 promoter-TSS (NM_001127221) chr1913617512 rockermeth rockermethSegs 1 52 794 promoter-TSS (NM_001127221)chr19 13617517 rockermeth rockermethSegs 1 16 795 promoter-TSS(NM_001127221) chr19 13617541 rockermeth rockermethSegs 1 44 796promoter-TSS (NM_001127221) chr19 13618356 rockermeth rockermethSegs 136 797 Intergenic chr19 13618391 rockermeth rockermethSegs 1 49 798Intergenic chr19 13700379 rockermeth rockermethSegs 1 59 799 Intergenicchr19 18836689 rockermeth rockermethSegs −1 4 800 intron (NM_001098482,chr19 18837043 rockermeth rockermethSegs −1 7 801 intron (NM_001098482,chr19 18837091 rockermeth rockermethSegs −1 6 802 intron (NM_001098482,chr19 18837098 rockermeth rockermethSegs −1 5 803 intron (NM_001098482,chr19 18837105 rockermeth rockermethSegs −1 8 804 intron (NM_001098482,chr19 34181556 rockermeth rockermethSegs −1 419 805 intron(NM_001127895, chr19 34181606 rockermeth rockermethSegs −1 421 806intron (NM_001127895, chr19 34181636 rockermeth rockermethSegs −1 420807 intron (NM_001127895, chr19 38527887 rockermeth rockermethSegs −1 71808 intron (NM_015073, chr19 38527913 rockermeth rockermethSegs −1 72809 intron (NM_015073, chr19 38527932 rockermeth rockermethSegs −1 73810 intron (NM_015073, chr19 38528016 rockermeth rockermethSegs −1 74811 intron (NM_015073, chr19 38528031 rockermeth rockermethSegs −1 70812 intron (NM_015073, chr19 38684235 rockermeth rockermethSegs −1 62813 exon (NM_015073, chr19 38684327 rockermeth rockermethSegs −1 63 814exon (NM_015073, chr19 38684338 rockermeth rockermethSegs −1 61 815 exon(NM_015073, chr19 38684363 rockermeth rockermethSegs −1 60 816 exon(NM_015073, chr19 48699558 rockermeth rockermethSegs −1 159 817 exon(NM_199341, chr19 48699578 rockermeth rockermethSegs −1 158 818 exon(NM_199341, chr19 48699588 rockermeth rockermethSegs −1 157 819 exon(NM_199341, chr19 48699615 rockermeth rockermethSegs −1 161 820 exon(NM_199341, chr19 48699628 rockermeth rockermethSegs −1 156 821 exon(NM_199341, chr19 48699667 rockermeth rockermethSegs −1 155 822 exon(NM_199341, chr19 48699717 rockermeth rockermethSegs −1 160 823 exon(NM_199341, chr19 55870392 rockermeth rockermethSegs −1 619 824 exon(NM_001145402, chr19 55870402 rockermeth rockermethSegs −1 620 825 exon(NM_001145402, chr19 55870407 rockermeth rockermethSegs −1 615 826 exon(NM_001145402, chr19 55870425 rockermeth rockermethSegs −1 618 827 exon(NM_001145402, chr19 55870439 rockermeth rockermethSegs −1 613 828 exon(NM_001145402, chr19 55870456 rockermeth rockermethSegs −1 616 829 exon(NM_001145402, chr19 55870462 rockermeth rockermethSegs −1 614 830 exon(NM_001145402, chr19 55870471 rockermeth rockermethSegs −1 617 831 exon(NM_001145402, chr19 55870886 rockermeth rockermethSegs −1 621 832 exon(NM_001145402, chr20 20180688 rockermeth rockermethSegs −1 414 833intron (NM_015585, chr20 20180732 rockermeth rockermethSegs −1 413 834intron (NM_015585, chr20 20188098 rockermeth rockermethSegs −1 409 835intron (NM_015585, chr20 20188151 rockermeth rockermethSegs −1 411 836intron (NM_015585, chr20 20206077 rockermeth rockermethSegs −1 416 837intron (NM_015585, chr20 20232312 rockermeth rockermethSegs −1 417 838exon (NM_015585, chr20 20232336 rockermeth rockermethSegs −1 412 839exon (NM_015585, chr20 20232350 rockermeth rockermethSegs −1 408 840exon (NM_015585, chr20 20232360 rockermeth rockermethSegs −1 410 841exon (NM_015585, chr20 20232370 rockermeth rockermethSegs −1 415 842exon (NM_015585, chr20 20232391 rockermeth rockermethSegs −1 418 843exon (NM_015585, chr20 20376947 rockermeth rockermethSegs −1 252 844intron (NM_020343, chr20 20376962 rockermeth rockermethSegs −1 251 845intron (NM_020343, chr20 20377074 rockermeth rockermethSegs −1 239 846intron (NM_020343, chr20 20377089 rockermeth rockermethSegs −1 249 847intron (NM_020343, chr20 20377110 rockermeth rockermethSegs −1 244 848intron (NM_020343, chr20 20377122 rockermeth rockermethSegs −1 247 849intron (NM_020343, chr20 20377130 rockermeth rockermethSegs −1 238 850intron (NM_020343, chr20 20377162 rockermeth rockermethSegs −1 248 851intron (NM_020343, chr20 20377169 rockermeth rockermethSegs −1 246 852intron (NM_020343, chr20 20377206 rockermeth rockermethSegs −1 250 853intron (NM_020343, chr20 20392139 rockermeth rockermethSegs −1 245 854intron (NM_020343, chr20 20392184 rockermeth rockermethSegs −1 235 855intron (NM_020343, chr20 20392215 rockermeth rockermethSegs −1 236 856intron (NM_020343, chr20 20392408 rockermeth rockermethSegs −1 237 857intron (NM_020343, chr20 20421295 rockermeth rockermethSegs −1 253 858intron (NM_020343, chr20 20421314 rockermeth rockermethSegs −1 254 859intron (NM_020343, chr20 20421345 rockermeth rockermethSegs −1 240 860intron (NM_020343, chr20 20421371 rockermeth rockermethSegs −1 243 861intron (NM_020343, chr20 20421396 rockermeth rockermethSegs −1 241 862intron (NM_020343, chr20 20421420 rockermeth rockermethSegs −1 242 863intron (NM_020343, chr20 20421459 rockermeth rockermethSegs −1 255 864intron (NM_020343, chr20 20421486 rockermeth rockermethSegs −1 256 865intron (NM_020343, chr20 31129481 rockermeth rockermethSegs −1 261 866intron (NM_001256798, chr20 36923352 rockermeth rockermethSegs −1 142867 Intergenic chr20 36923369 rockermeth rockermethSegs −1 140 868Intergenic chr20 36923397 rockermeth rockermethSegs −1 141 869Intergenic chr20 61013054 rockermeth rockermethSegs −1 445 870 intron(NR_033263, chr20 61013094 rockermeth rockermethSegs −1 440 871 intron(NR_033263, chr20 61013113 rockermeth rockermethSegs −1 444 872 intron(NR_033263, chr20 61013148 rockermeth rockermethSegs −1 437 873 intron(NR_033263, chr20 61013167 rockermeth rockermethSegs −1 434 874 intron(NR_033263, chr20 61013187 rockermeth rockermethSegs −1 433 875 intron(NR_033263, chr20 61013226 rockermeth rockermethSegs −1 436 876 intron(NR_033263, chr20 61013242 rockermeth rockermethSegs −1 438 877 intron(NR_033263, chr20 61013251 rockermeth rockermethSegs −1 435 878 intron(NR_033263, chr20 61013263 rockermeth rockermethSegs −1 447 879 intron(NR_033263, chr20 61013303 rockermeth rockermethSegs −1 448 880 intron(NR_033263, chr20 61013339 rockermeth rockermethSegs −1 442 881 intron(NR_033263, chr20 61013474 rockermeth rockermethSegs −1 446 882 intron(NR_033263, chr20 61013515 rockermeth rockermethSegs −1 441 883 intron(NR_033263, chr20 61020520 rockermeth rockermethSegs −1 439 884 intron(NR_033263, chr20 61021747 rockermeth rockermethSegs −1 443 885 intron(NR_033263, chr21 43442046 rockermeth rockermethSegs −1 574 886promoter-TSS (NR_119385) chr21 43442055 rockermeth rockermethSegs −1 573887 promoter-TSS (NR_119385) chr21 43442083 rockermeth rockermethSegs −1575 888 promoter-TSS (NR_119385) chr21 43442252 rockermethrockermethSegs −1 576 889 promoter-TSS (NR_027273) chr21 43442338rockermeth rockermethSegs −1 572 890 promoter-TSS (NR_027273) chr2143442384 rockermeth rockermethSegs −1 577 891 promoter-TSS (NR_027273)chr21 44836763 rockermeth rockermethSegs −1 492 892 exon (NM_001320643,chr21 44836797 rockermeth rockermethSegs −1 489 893 exon (NM_001320643,chr21 144836823 rockermeth rockermethSegs −1 493 894 exon (NM_001320643,chr21 44836842 rockermeth rockermethSegs −1 490 895 exon (NM_001320643,chr21 44836924 rockermeth rockermethSegs −1 484 896 exon (NM_001320643,chr21 44836936 rockermeth rockermethSegs −1 487 897 exon (NM_001320643,chr21 44836971 rockermeth rockermethSegs −1 480 898 exon (NM_001320643,chr21 44837026 rockermeth rockermethSegs −1 481 899 intron (NM_173354,chr21 44837044 rockermeth rockermethSegs −1 482 900 intron (NM_173354,chr21 44837052 rockermeth rockermethSegs −1 488 901 intron (NM_173354,chr21 44837060 rockermeth rockermethSegs −1 485 902 intron (NM_173354,chr21 44837074 rockermeth rockermethSegs −1 486 903 intron (NM_173354,chr21 44837115 rockermeth rockermethSegs −1 483 904 intron (NM_173354,chr21 44837132 rockermeth rockermethSegs −1 491 905 intron (NM_173354,chr21 44837157 rockermeth rockermethSegs −1 494 906 intron (NM_173354,chr21 145653981 rockermeth rockermethSegs −1 233 907 intron (NM_015259,chr21 45654156 rockermeth rockermethSegs −1 234 908 intron (NM_015259,chr22 47444997 rockermeth rockermethSegs −1 727 909 intron (NM_014346,chr22 47445037 rockermeth rockermethSegs −1 724 910 intron (NM_014346,chr22 47447406 rockermeth rockermethSegs −1 726 911 intron (NM_014346,chr22 47447603 rockermeth rockermethSegs −1 725 912 intron (NM_014346,chrX 104458760 rockermeth rockermethSegs −1 765 913 intron (NM_017416,chrX 104692650 rockermeth rockermethSegs −1 766 914 intron (NM_017416,chrX 104804571 rockermeth rockermethSegs −1 764 915 intron (NM_017416,chrX 104891135 rockermeth rockermethSegs −1 763 916 intron (NM_017416,chrX 105016634 rockermeth rockermethSegs −1 767 917 Intergenic chrX105016672 rockermeth rockermethSegs −1 768 918 Intergenic chrX 128926432rockermeth rockermethSegs −1 526 919 exon (NM_018990, chr2 209103955epi_snvs snv_frequency 1 1 intron (NM_005896, chr4 106155150 epi_snvssnv_frequency 1 2 exon (NM_001127208, chr4 106155913 epi_snvssnv_frequency 1 3 exon (NM_001127208, chr4 106156460 epi_snvssnv_frequency 1 4 exon (NM_001127208, chr4 106156742 epi_snvssnv_frequency 1 5 exon (NM_001127208, chr4 106157415 epi_snvssnv_frequency 1 6 exon (NM_001127208, chr4 106164901 epi_snvssnv_frequency 1 7 TTS (NM_017628) chr4 106196236 epi_snvs snv_frequency1 8 exon (NM_001127208, chr7 33732332 AUC_Δβ_GOI snv_frequency 1 1Intergenic chr7 140453119 epi_snvs snv_frequency 1 9 exon (NM_004333,chr7 140481387 epi_snvs snv_frequency 1 10 exon (NM_004333, chr7140481426 epi_snvs snv_frequency 1 11 exon (NM_004333, chr7 140500421epi_snvs snv_frequency 1 12 intron (NR_148928, chr7 140507748 epi_snvssnv_frequency 1 13 exon (NM_004333, chr7 140507954 epi_snvssnv_frequency 1 14 intron (NM_001354609, chr7 140624441 epi_snvssnv_frequency 1 15 exon (NM_004333, chr14 38061176 FOXA1_snvssnv_frequency 1 1 exon (NM_004496, chr14 38061319 FOXA1_snvssnv_frequency 1 2 exon (NM_004496, chr14 38061830 FOXA1_snvssnv_frequency 1 3 exon (NM_004496, chr17 7572948 TP53_snvs snv_frequency1 1 exon (NM_000546, chr17 7573967 TP53_snvs snv_frequency 1 2 exon(NM_000546, chr17 7576524 TP53_snvs snv_frequency 1 3 exon(NM_001126117, chr17 7576838 TP53_snvs snv_frequency 1 4 exon(NM_001126117, chr17 7577020 TP53_snvs snv_frequency 1 5 exon(NM_001126117, chr17 7577483 TP53_snvs snv_frequency 1 6 exon(NM_001126117, chr17 7578161 TP53_snvs snv_frequency 1 7 exon(NM_001126117, chr17 7578373 TP53_snvs snv_frequency 1 8 promoter-TSS(NM_001276697) chr17 7579297 TP53_snvs snv_frequency 1 9 promoter-TSS(NM_001126117) chr17 7579393 TP53_snvs snv_frequency 1 10 promoter-TSS(NM_001126117) chr17 7579506 TP53_snvs snv_frequency 1 11 promoter-TSS(NM_001126117) chr17 7579701 TP53_snvs snv_frequency 1 12 promoter-TSS(NM_001126117) chr17 7579846 TP53_snvs snv_frequency 1 13 exon(NM_000546, chr17 47696409 SPOP_snvs snv_frequency 1 1 exon(NM_001007228, chr17 47696673 SPOP_snvs snv_frequency 1 2 exon(NM_001007228, chr20 31375142 epi_snvs snv_frequency 1 16 exon(NM_175848, chr20 31380384 epi_snvs snv_frequency 1 17 intron(NM_175849, chr20 31381300 epi_snvs snv_frequency 1 18 intron(NM_175849, chr20 31386255 epi_snvs snv_frequency 1 19 exon (NM_175848,chr20 31388050 epi_snvs snv_frequency 1 20 exon (NM_175848, chr2031389120 epi_snvs snv_frequency 1 21 exon (NM_175848, chr20 31393185epi_snvs snv_frequency 1 22 exon (NM_175848, chr20 31395662 epi_snvssnv_frequency 1 23 exon (NM_175848, chrX 66121000 AR_Enhancersnv_frequency 1 1 Intergenic chrX 66766332 AR_snvs snv_frequency 1 1exon (NM_001348064, chrX 66931448 AR_snvs snv_frequency 1 2 exon(NM_000044, chrX 66937357 AR_snvs snv_frequency 1 3 exon (NM_000044,chrX 66943528 AR_snvs snv_frequency 1 4 exon (NM_000044, chr2 25452399DMS_GOI AUC_Δβ_GOI −1 1 non-coding (NR_135490, chr2 25452969 DMS_GOIAUC_Δβ_GOI −1 2 non-coding (NR_135490, chr2 25453099 DMS_GOI AUC_Δβ_GOI−1 3 non-coding (NR_135490, chr2 25453105 DMS_GOI AUC_Δβ_GOI −1 4non-coding (NR_135490, chr2 25453799 DMS_GOI AUC_Δβ_GOI −1 5 non-coding(NR_135490, chr2 25453898 DMS_GOI AUC_Δβ_GOI −1 6 non-coding (NR_135490,chr2 25453899 DMS_GOI AUC_Δβ_GOI −1 7 non-coding (NR_135490, chr225453913 DMS_GOI AUC_Δβ_GOI −1 8 non-coding (NR_135490, chr2 25499982DMS_GOI AUC_Δβ_GOI 1 9 intron (NR_135490, chr2 25500271 DMS_GOIAUC_Δβ_GOI 1 10 intron (NR_135490, chr2 25500272 DMS_GOI AUC_Δβ_GOI 1 11intron (NR_135490, chr2 239147428 DMS_GOI AUC_Δβ_GOI −1 12 3′ UTR chr2239147440 DMS_GOI AUC_Δβ_GOI −1 13 3′ UTR chr2 239147441 DMS_GOIAUC_Δβ_GOI −1 14 3′ UTR chr2 239147485 DMS_GOI AUC_Δβ_GOI −1 15 exon(NM_018645, chr2 239147486 DMS_GOI AUC_Δβ_GOI −1 16 exon (NM_018645,chr2 239147522 DMS_GOI AUC_Δβ_GOI −1 17 exon (NM_018645, chr2 239147534DMS_GOI AUC_Δβ_GOI −1 18 exon (NM_018645, chr2 239147589 DMS_GOIAUC_Δβ_GOI −1 19 exon (NM_018645, chr2 239147601 DMS_GOI AUC_Δβ_GOI −120 exon (NM_018645, chr2 239147614 DMS_GOI AUC_Δβ_GOI −1 21 exon(NM_018645, chr2 239147637 DMS_GOI AUC_Δβ_GOI −1 22 exon (NM_018645,chr2 239147649 DMS_GOI AUC_Δβ_GOI −1 23 exon (NM_018645, chr2 239147665DMS_GOI AUC_Δβ_GOI −1 24 exon (NM_018645, chr2 239149894 DMS_GOIAUC_Δβ_GOI −1 25 Intergenic chr2 239149895 DMS_GOI AUC_Δβ_GOI −1 26Intergenic chr3 12838468 DMS_GOI AUC_Δβ_GOI −1 27 intron (NM_012298,chr3 50660608 DMS_GOI AUC_Δβ_GOI 1 28 intron (NM_001243925, chr350670155 DMS_GOI AUC_Δβ_GOI 1 29 intron (NM_001243925, chr3 128202781DMS_GOI AUC_Δβ_GOI 1 30 exon (NM_032638, chr3 128202787 DMS_GOIAUC_Δβ_GOI 1 31 exon (NM_032638, chr3 128202792 DMS_GOI AUC_Δβ_GOI 1 32exon (NM_032638, chr3 128202795 DMS_GOI AUC_Δβ_GOI 1 33 exon (NM_032638,chr3 128202796 DMS_GOI AUC_Δβ_GOI 1 34 exon (NM_032638, chr3 128202884DMS_GOI AUC_Δβ_GOI 1 35 intron (NM_001145661, chr3 128202894 DMS_GOIAUC_Δβ_GOI 1 36 intron (NM_001145661, chr3 128202895 DMS_GOI AUC_Δβ_GOI1 37 intron (NM_001145661, chr3 128202927 DMS_GOI AUC_Δβ_GOI 1 38 intron(NM_001145661, chr3 128202928 DMS_GOI AUC_Δβ_GOI 1 39 intron(NM_001145661, chr3 128205157 DMS_GOI AUC_Δβ_GOI 1 40 exon (NM_032638,chr3 128205179 DMS_GOI AUC_Δβ_GOI 1 41 exon (NM_032638, chr3 128205180DMS_GOI AUC_Δβ_GOI 1 42 exon (NM_032638, chr3 128205195 DMS_GOIAUC_Δβ_GOI 1 43 exon (NM_032638, chr3 128205196 DMS_GOI AUC_Δβ_GOI 1 44exon (NM_032638, chr3 128205210 DMS_GOI AUC_Δβ_GOI 1 45 intron(NM_001145661, chr3 128210723 DMS_GOI AUC_Δβ_GOI 1 46 intron (NR_125398,chr3 128210727 DMS_GOI AUC_Δβ_GOI 1 47 intron (NR_125398, chr3 128212207DMS_GOI AUC_Δβ_GOI 1 48 promoter-TSS (NM_032638) chr3 185817004 DMS_GOIAUC_Δβ_GOI −1 49 intron (NM_004454, chr4 16084875 DMS_GOI AUC_Δβ_GOI 150 promoter-TSS (NM_001371407) chr4 16084881 DMS_GOI AUC_Δβ_GOI 1 51promoter-TSS (NM_001371407) chr4 16084898 DMS_GOI AUC_Δβ_GOI 1 52promoter-TSS (NM_001371407) chr4 16085260 DMS_GOI AUC_Δβ_GOI 1 53promoter-TSS (NM_001145852) chr4 16085380 DMS_GOI AUC_Δβ_GOI 1 54promoter-TSS (NM_001145852) chr4 16085396 DMS_GOI AUC_Δβ_GOI 1 55promoter-TSS (NM_001145852) chr4 16085398 DMS_GOI AUC_Δβ_GOI 1 56promoter-TSS (NM_001145852) chr4 16085401 DMS_GOI AUC_Δβ_GOI 1 57promoter-TSS (NM_001145852) chr5 172661872 DMS_GOI AUC_Δβ_GOI 1 58 exon(NM_004387, chr5 172661874 DMS_GOI AUC_Δβ_GOI 1 59 exon (NM_004387, chr634522044 DMS_GOI AUC_Δβ_GOI 1 60 intron (NM_012391, chr6 34523223DMS_GOI AUC_Δβ_GOI 1 61 intron (NM_012391, chr8 11561726 DMS_GOIAUC_Δβ_GOI 1 62 promoter-TSS (NM_002052) chr8 11565855 DMS_GOIAUC_Δβ_GOI 1 63 exon (NM_002052, chrS 11566229 DMS_GOI AUC_Δβ_GOI 1 64exon (NM_002052, chr8 11583613 DMS_GOI AUC_Δβ_GOI −1 65 intron(NM_002052, chr8 11583614 DMS_GOI AUC_Δβ_GOI −1 66 intron (NM_002052,chr9 126775063 DMS_GOI AUC_Δβ_GOI 1 67 intron (NM_004789, chr9 126775082DMS_GOI AUC_Δβ_GOI 1 68 intron (NM_004789, chr9 126776013 DMS_GOIAUC_Δβ_GOI 1 69 intron (NM_004789, chr9 126776231 DMS_GOI AUC_Δβ_GOI 170 intron (NM_004789, chr9 139437635 DMS_GOI AUC_Δβ_GOI −1 71 intron(NM_017617, chr9 139437679 DMS_GOI AUC_Δβ_GOI −1 72 intron (NM_017617,chr10 23481414 DMS_GOI AUC_Δβ_GOI 1 73 5′ UTR chr10 23481415 DMS_GOIAUC_Δβ_GOI 1 74 5′ UTR chr10 23481417 DMS_GOI AUC_Δβ_GOI 1 75 5′ UTRchr10 23481445 DMS_GOI AUC_Δβ_GOI 1 76 5′ UTR chr10 23481447 DMS_GOIAUC_Δβ_GOI 1 77 5′ UTR chr10 23481448 DMS_GOI AUC_Δβ_GOI 1 78 5′ UTRchr10 23481451 DMS_GOI AUC_Δβ_GOI 1 79 5′ UTR chr10 23481461 DMS_GOIAUC_Δβ_GOI 1 80 exon (NM_178161, chr10 23481462 DMS_GOI AUC_Δβ_GOI 1 81exon (NM_178161, chr10 23481463 DMS_GOI AUC_Δβ_GOI 1 82 exon (NM_178161,chr10 56699066 DMS_GOI AUC_Δβ_GOI −1 83 intron (NM_001354404, chr1056699077 DMS_GOI AUC_Δβ_GOI −1 84 intron (NM_001354404, chr10 57391015DMS_GOI AUC_Δβ_GOI 1 85 Intergenic chr11 69451450 DMS_GOI AUC_Δβ_GOI 186 Intergenic chr12 103344993 DMS_GOI AUC_Δβ_GOI −1 87 intron(NM_001354304, chr12 103344998 DMS_GOI AUC_Δβ_GOI −1 88 intron(NM_001354304, chr12 103345006 DMS_GOI AUC_Δβ_GOI −1 89 intron(NM_001354304, chr12 103345029 DMS_GOI AUC_Δβ_GOI −1 90 intron(NM_001354304, chr12 103345033 DMS_GOI AUC_Δβ_GOI −1 91 intron(NM_001354304, chr14 51560040 DMS_GOI AUC_Δβ_GOI −1 92 intron(NM_052978, chr14 51560162 DMS_GOI AUC_Δβ_GOI −1 93 intron (NM_052978,chr14 51560191 DMS_GOI AUC_Δβ_GOI −1 94 intron (NM_052978, chr1451560193 DMS_GOI AUC_Δβ_GOI −1 95 intron (NM_052978, chr14 51560208DMS_GOI AUC_Δβ_GOI −1 96 intron (NM_052978, chr14 51560259 DMS_GOIAUC_Δβ_GOI −1 97 intron (NM_052978, chr14 51560261 DMS_GOI AUC_Δβ_GOI −198 intron (NM_052978, chr14 51560275 DMS_GOI AUC_Δβ_GOI −1 99 intron(NM_052978, chr14 65409361 DMS_GOI AUC_Δβ_GOI −1 100 promoter-TSS(NM_002083) chr14 93385930 DMS_GOI AUC_Δβ_GOI 1 101 Intergenic chr1493423499 DMS_GOI AUC_Δβ_GOI −1 102 intron (NM_001142593, chr14 93423555DMS_GOI AUC_Δβ_GOI −1 103 intron (NM_001142593, chr14 93425158 DMS_GOIAUC_Δβ_GOI −1 104 intron (NM_001142593, chr14 93425189 DMS_GOIAUC_Δβ_GOI −1 105 intron (NM_001142593, chr14 93425207 DMS_GOIAUC_Δβ_GOI −1 106 intron (NM_001142593, chr14 93425289 DMS_GOIAUC_Δβ_GOI −1 107 intron (NM_001142593, chr14 93425328 DMS_GOIAUC_Δβ_GOI −1 108 intron (NM_001142593, chr14 93425517 DMS_GOIAUC_Δβ_GOI −1 109 intron (NM_001142593, chr14 93425684 DMS_GOIAUC_Δβ_GOI −1 110 intron (NM_001142593, chr14 93425685 DMS_GOIAUC_Δβ_GOI −1 111 intron (NM_001142593, chr14 93425738 DMS_GOIAUC_Δβ_GOI −1 112 intron (NM_001142593, chr14 93426226 DMS_GOIAUC_Δβ_GOI −1 113 intron (NM_001142593, chr14 93426244 DMS_GOIAUC_Δβ_GOI −1 114 intron (NM_001142593, chr14 93426333 DMS_GOIAUC_Δβ_GOI −1 115 intron (NM_001142593, chr14 93426378 DMS_GOIAUC_Δβ_GOI −1 116 intron (NM_001142593, chr14 93426872 DMS_GOIAUC_Δβ_GOI −1 117 intron (NM_001142593, chr14 93426913 DMS_GOIAUC_Δβ_GOI −1 118 intron (NM_001142593, chr14 93426914 DMS_GOIAUC_Δβ_GOI −1 119 intron (NM_001142593, chr14 93426959 DMS_GOIAUC_Δβ_GOI −1 120 intron (NM_001142593, chr14 93439910 DMS_GOIAUC_Δβ_GOI 1 121 intron (NM_001142593, chr18 31323189 DMS_GOI AUC_Δβ_GOI−1 122 exon (NM_030632, chr18 31323202 DMS_GOI AUC_Δβ_GOI −1 123 exon(NM_030632, chr18 53175324 DMS_GOI AUC_Δβ_GOI −1 124 intron(NM_001369572, chr18 53305364 DMS_GOI AUC_Δβ_GOI −1 125 Intergenic chr1853305490 DMS_GOI AUC_Δβ_GOI −1 126 Intergenic chr19 11086495 DMS_GOIAUC_Δβ_GOI 1 127 intron (NM_003072, chr19 39993532 DMS_GOI AUC_Δβ_GOI 1128 exon (NM_016941, chr19 39993551 DMS_GOI AUC_Δβ_GOI 1 129 exon(NM_016941, chr19 39993567 DMS_GOI AUC_Δβ_GOI 1 130 exon (NM_016941,chr19 39993606 DMS_GOI AUC_Δβ_GOI 1 131 exon (NM_016941, chr19 42618585DMS_GOI AUC_Δβ_GOI −1 132 intron (NM_002698, chr19 42618760 DMS_GOIAUC_Δβ_GOI −1 133 intron (NM_002698, chr19 42618787 DMS_GOI AUC_Δβ_GOI−1 134 intron (NM_002698, chr19 42618789 DMS_GOI AUC_Δβ_GOI −1 135intron (NM_002698, chr19 42618823 DMS_GOI AUC_Δβ_GOI −1 136 intron(NM_002698, chr20 20232309 DMS_GOI AUC_Δβ_GOI −1 137 exon (NM_015585,chr20 20232319 DMS_GOI AUC_Δβ_GOI −1 138 exon (NM_015585, chr20 20232333DMS_GOI AUC_Δβ_GOI −1 139 exon (NM_015585, chr20 20232347 DMS_GOIAUC_Δβ_GOI −1 140 exon (NM_015585, chr20 20232348 DMS_GOI AUC_Δβ_GOI −1141 exon (NM_015585, chr20 20232351 DMS_GOI AUC_Δβ_GOI −1 142 exon(NM_015585, chr20 20232352 DMS_GOI AUC_Δβ_GOI −1 143 exon (NM_015585,chr20 20232357 DMS_GOI AUC_Δβ_GOI −1 144 exon (NM_015585, chr20 20232358DMS_GOI AUC_Δβ_GOI −1 145 exon (NM_015585, chr20 20232367 DMS_GOIAUC_Δβ_GOI −1 146 exon (NM_015585, chr20 20232388 DMS_GOI AUC_Δβ_GOI −1147 exon (NM_015585, chr20 20266415 DMS_GOI AUC_Δβ_GOI 1 148 intron(NM_015585, chr20 20376954 DMS_GOI AUC_Δβ_GOI −1 149 intron (NM_020343,chr20 20376969 DMS_GOI AUC_Δβ_GOI −1 150 intron (NM_020343, chr2020377086 DMS_GOI AUC_Δβ_GOI −1 151 intron (NM_020343, chr20 20377158DMS_GOI AUC_Δβ_GOI −1 152 intron (NM_020343, chr20 20377165 DMS_GOIAUC_Δβ_GOI −1 153 intron (NM_020343, chr20 20421292 DMS_GOI AUC_Δβ_GOI−1 154 intron (NM_020343, chr20 20421311 DMS_GOI AUC_Δβ_GOI −1 155intron (NM_020343, chr20 20421456 DMS_GOI AUC_Δβ_GOI −1 156 intron(NM_020343, chr20 20421483 DMS_GOI AUC_Δβ_GOI −1 157 intron (NM_020343,chr20 20433160 DMS_GOI AUC_Δβ_GOI −1 158 intron (NM_020343, chr2020433163 DMS_GOI AUC_Δβ_GOI −1 159 intron (NM_020343, chr20 20433166DMS_GOI AUC_Δβ_GOI −1 160 intron (NM_020343, chr20 20433198 DMS_GOIAUC_Δβ_GOI −1 161 intron (NM_020343, chr20 20433208 DMS_GOI AUC_Δβ_GOI−1 162 intron (NM_020343, chr20 20433248 DMS_GOI AUC_Δβ_GOI −1 163intron (NM_020343, chr20 20433256 DMS_GOI AUC_Δβ_GOI −1 164 intron(NM_020343, chr20 20433263 DMS_GOI AUC_Δβ_GOI −1 165 intron (NM_020343,chr20 20433284 DMS_GOI AUC_Δβ_GOI −1 166 intron (NM_020343, chr2020433293 DMS_GOI AUC_Δβ_GOI −1 167 intron (NM_020343, chr20 21490704DMS_GOI AUC_Δβ_GOI 1 168 TTS (NM_002509) chr20 21490799 DMS_GOIAUC_Δβ_GOI 1 169 TTS (NM_002509) chr20 21490807 DMS_GOI AUC_Δβ_GOI 1 170TTS (NM_002509) chr20 21494139 DMS_GOI AUC_Δβ_GOI 1 171 exon (NM_002509,chr20 21494141 DMS_GOI AUC_Δβ_GOI 1 172 exon (NM_002509, chr20 21494237DMS_GOI AUC_Δβ_GOI 1 173 exon (NM_002509, chr21 22564429 DMS_GOIAUC_Δβ_GOI −1 174 intron (NM_001352597, chr21 42850711 DMS_GOIAUC_Δβ_GOI 1 175 intron (NM_005656, chr21 42860322 DMS_GOI AUC_Δβ_GOI 1176 exon (NM_001135099, chr21 42860341 DMS_GOI AUC_Δβ_GOI 1 177 exon(NM_001135099, chr21 42880610 DMS_GOI AUC_Δβ_GOI 1 178 promoter-TSS(NM_001135099) chr21 42880614 DMS_GOI AUC_Δβ_GOI 1 179 promoter-TSS(NM_001135099) chr21 42880659 DMS_GOI AUC_Δβ_GOI 1 180 promoter-TSS(NM_001135099) chr21 42880668 DMS_GOI AUC_Δβ_GOI 1 181 promoter-TSS(NM_001135099) chr1 3052478 DMS_GOI AUC_Δβ_TS −1 182 intron (NM_199454,chr1 26735081 DMS_GOI AUC_Δβ_TS 1 183 Intergenic chr1 26735241 DMS_GOIAUC_Δβ_TS 1 184 Intergenic chr1 26735243 DMS_GOI AUC_Δβ_TS 1 185Intergenic chr1 26735251 DMS_GOI AUC_Δβ_TS 1 186 Intergenic chr165721361 DMS_GOI AUC_Δβ_TS −1 187 Intergenic chr1 229195756 DMS_GOIAUC_Δβ_TS 1 188 Intergenic chr2 23807028 DMS_GOI AUC_Δβ_TS −1 189 intron(NM_052920, chr2 171679652 DMS_GOI AUC_Δβ_TS 1 190 intron (NM_013445,chr2 236877206 DMS_GOI AUC_Δβ_TS −1 191 exon (NM_001037131, chr2242549633 DMS_GOI AUC_Δβ_TS 1 192 intron (NM_015963, chr2 242549635DMS_GOI AUC_Δβ_TS 1 193 intron (NM_015963, chr2 242549638 DMS_GOIAUC_Δβ_TS 1 194 intron (NM_015963, chr2 242549659 DMS_GOI AUC_Δβ_TS 1195 intron (NM_015963, chr3 26664523 DMS_GOI AUC_Δβ_TS 1 196promoter-TSS (NM_001317808) chr3 126664525 DMS_GOI AUC_Δβ_TS 1 197promoter-TSS (NM_001317808) chr3 111431556 DMS_GOI AUC_Δβ_TS −1 198intron (NM_001185106, chr4 169799044 DMS_GOI AUC_Δβ_TS 1 199 exon(NM_001166110, chr5 138441347 DMS_GOI AUC_Δβ_TS −1 200 intron(NM_001037633, chr5 138441374 DMS_GOI AUC_Δβ_TS −1 201 intron(NM_001037633, chr5 138441376 DMS_GOI AUC_Δβ_TS −1 202 intron(NM_001037633, chr5 176038510 DMS_GOI AUC_Δβ_TS 1 203 Intergenic chr5176038524 DMS_GOI AUC_Δβ_TS 1 204 Intergenic chr5 176038525 DMS_GOIAUC_Δβ_TS 1 205 Intergenic chr5 176038562 DMS_GOI AUC_Δβ_TS 1 206Intergenic chr5 179401799 DMS_GOI AUC_Δβ_TS −1 207 intron (NM_018434,chr6 15265454 DMS_GOI AUC_Δβ_TS 1 208 intron (NM_001267040, chr6168462402 DMS_GOI AUC_Δβ_TS −1 209 intron (NR_110312, chr6 168462447DMS_GOI AUC_Δβ_TS −1 210 intron (NR_110312, chr6 170578588 DMS_GOIAUC_Δβ_TS −1 211 intron (NR_126021, chr7 2968311 DMS_GOI AUC_Δβ_TS −1212 exon (NM_032415, chr7 2968441 DMS_GOI AUC_Δβ_TS −1 213 intron(NM_001324281, chr7 2968442 DMS_GOI AUC_Δβ_TS −1 214 intron(NM_001324281, chr7 2968451 DMS_GOI AUC_Δβ_TS −1 215 intron(NM_001324281, chr7 2968454 DMS_GOI AUC_Δβ_TS −1 216 intron(NM_001324281, chr7 5572006 DMS_GOI AUC_Δβ_TS 1 217 Intergenic chr7150812220 DMS_GOI AUC_Δβ_TS 1 218 exon (NM_001308305, chr8 47570600DMS_GOI AUC_Δβ_TS −1 219 Intergenic chr9 116411412 DMS_GOI AUC_Δβ_TS −1220 Intergenic chr9 124498726 DMS_GOI AUC_Δβ_TS 1 221 intron (NM_032552,chr9 124620057 DMS_GOI AUC_Δβ_TS −1 222 intron (NM_001139442, chr10676777 DMS_GOI AUC_Δβ_TS −1 223 non-coding (NR_147612, chr10 676811DMS_GOI AUC_Δβ_TS −1 224 non-coding (NR_147612, chr11 2000638 DMS_GOIAUC_Δβ_TS −1 225 Intergenic chr11 11600192 DMS_GOI AUC_Δβ_TS −1 226intron (NM_001363464, chr11 11600210 DMS_GOI AUC_Δβ_TS −1 227 intron(NM_001363464, chr11 11600228 DMS_GOI AUC_Δβ_TS −1 228 intron(NM_001363464, chr11 11600230 DMS_GOI AUC_Δβ_TS −1 229 intron(NM_001363464, chr11 11600231 DMS_GOI AUC_Δβ_TS −1 230 intron(NM_001363464, chr11 11600240 DMS_GOI AUC_Δβ_TS −1 231 intron(NM_001363464, chr11 64120601 DMS_GOI AUC_Δβ_TS −1 232 exon (NM_032251,chr11 70851727 DMS_GOI AUC_Δβ_TS −1 233 intron (NM_012309, chr1240618451 DMS_GOI AUC_Δβ_TS 1 234 promoter-TSS (NM_198578) chr12 40618493DMS_GOI AUC_Δβ_TS 1 235 promoter-TSS (NM_198578) chr15 32385689 DMS_GOIAUC_Δβ_TS −1 236 intron (NM_000746, chr15 68723747 DMS_GOI AUC_Δβ_TS 1237 intron (NM_001004439, chr15 89954601 DMS_GOI AUC_Δβ_TS 1 238 intron(NR_160724, chr15 89954603 DMS_GOI AUC_Δβ_TS 1 239 intron (NR_160724,chr15 89954605 DMS_GOI AUC_Δβ_TS 1 240 intron (NR_160724, chr15 89959942DMS_GOI AUC_Δβ_TS 1 241 intron (NR_160724, chr16 85498200 DMS_GOIAUC_Δβ_TS −1 242 Intergenic chr16 85498219 DMS_GOI AUC_Δβ_TS −1 243Intergenic chr16 85498220 DMS_GOI AUC_Δβ_TS −1 244 Intergenic chr1685498227 DMS_GOI AUC_Δβ_TS −1 245 Intergenic : chr16 85498781 DMS_GOIAUC_Δβ_TS −1 246 Intergenic chr16 85519155 DMS_GOI AUC_Δβ_TS −1 247Intergenic chr16 85519162 DMS_GOI AUC_Δβ_TS −1 248 Intergenic chr1685519165 DMS_GOI AUC_Δβ_TS −1 249 Intergenic chr16 85519168 DMS_GOIAUC_Δβ_TS −1 250 Intergenic chr16 85519171 DMS_GOI AUC_Δβ_TS −1 251Intergenic chr16 85519173 DMS_GOI AUC_Δβ_TS −1 252 Intergenic chr1685519303 DMS_GOI AUC_Δβ_TS −1 253 Intergenic chr16 88715953 DMS_GOIAUC_Δβ_TS −1 254 intron (NM_000101, chr17 28299568 DMS_GOI AUC_Δβ_TS −1255 intron (NR_026738, chr17 80372745 DMS_GOI AUC_Δβ_TS 1 256 intron(NR_033265, chr17 80372760 DMS_GOI AUC_Δβ_TS 1 257 intron (NR_033265,chr17 80372761 DMS_GOI AUC_Δβ_TS 1 258 intron (NR_033265, chr17 80372766DMS_GOI AUC_Δβ_TS 1 259 intron (NR_033265, chr17 80372767 DMS_GOIAUC_Δβ_TS 1 260 intron (NR_033265, chr17 80372770 DMS_GOI AUC_Δβ_TS 1261 intron (NR_033265, chr17 80372771 DMS_GOI AUC_Δβ_TS 1 262 intron(NR_033265, chr17 80372793 DMS_GOI AUC_Δβ_TS 1 263 intron (NR_033265,chr18 57364080 DMS_GOI AUC_Δβ_TS 1 264 intron (NM_133459, chr19 591647DMS_GOI AUC_Δβ_TS 1 265 intron (NM_001194, chr19 591656 DMS_GOIAUC_Δβ_TS 1 266 intron (NM_001194, chr19 591660 DMS_GOI AUC_Δβ_TS 1 267intron (NM_001194, chr19 591662 DMS_GOI AUC_Δβ_TS 1 268 intron(NM_001194, chr19 591682 DMS_GOI AUC_Δβ_TS 1 269 intron (NM_001194,chr19 591683 DMS_GOI AUC_Δβ_TS 1 270 intron (NM_001194, chr19 591684DMS_GOI AUC_Δβ_TS 1 271 intron (NM_001194, chr19 591685 DMS_GOIAUC_Δβ_TS 1 272 intron (NM_001194, chr19 591688 DMS_GOI AUC_Δβ_TS 1 273intron (NM_001194, chr19 18837089 DMS_GOI AUC_Δβ_TS −1 274 intron(NM_001098482, chr19 18837102 DMS_GOI AUC_Δβ_TS −1 275 intron(NM_001098482, chr20 3778162 DMS_GOI AUC_Δβ_TS −1 276 intron (NM_004358,chr20 32156432 DMS_GOI AUC_Δβ_TS −1 277 intron (NM_001039709, chr2048099327 DMS_GOI AUC_Δβ_TS 1 278 promoter-TSS (NM_004975) chr20 48099339DMS_GOI AUC_Δβ_TS 1 279 promoter-TSS (NM_004975) chrX 36981727 DMS_GOIAUC_Δβ_TS 1 280 Intergenic chrX 36981729 DMS_GOI AUC_Δβ_TS 1 281Intergenic chr1 24392969 P_DEgenes ExpMeth 1 intron (NM_152372, chr124410522 P_DEgenes ExpMeth 2 intron (NM_152372, chr1 24434829 P_DEgenesExpMeth 3 intron (NM_152372, chr1 24438565 P_DEgenes ExpMeth 4promoter-TSS (NM_152372) chr1 27240357 P_DEgenes ExpMeth 5 promoter-TSS(NM_021969) chr1 50513586 P_DEgenes ExpMeth 6 promoter-TSS(NM_001324208) chr1 50569482 P_DEgenes ExpMeth 7 promoter-TSS(NM_001144776) chr1 50571262 P_DEgenes ExpMeth 8 promoter-TSS(NM_001144775) chr1 50571864 P_DEgenes ExpMeth 9 promoter-TSS(NM_001144775) chr1 50574505 P_DEgenes ExpMeth 10 promoter-TSS(NM_001144774) chr1 50574538 P_DEgenes ExpMeth 11 promoter-TSS(NM_001144774) chr1 50575198 P_DEgenes ExpMeth 12 promoter-TSS(NM_001324217) chr1 50575278 P_DEgenes ExpMeth 13 promoter-TSS(NM_001324217) chr1 50575388 P_DEgenes ExpMeth 14 promoter-TSS(NM_001324217) chr1 50610525 P_DEgenes ExpMeth 15 intron (NR_136725,chr1 50642702 P_DEgenes ExpMeth 16 exon (NM_001144774, chr1 78445126P_DEgenes ExpMeth 17 promoter-TSS (NM_001317099) chr1 78511486 P_DEgenesExpMeth 18 promoter-TSS (NM_017655) chr1 114521963 P_DEgenes ExpMeth 19promoter-TSS (NM_001286353) chr1 114521965 P_DEgenes ExpMeth 20promoter-TSS (NM_001286353) chr1 114522013 P_DEgenes ExpMeth 21promoter-TSS (NM_001286353) chr1 114522595 P_DEgenes ExpMeth 22 exon(NM_001286352, chr1 152956457 P_DEgenes ExpMeth 23 promoter-TSS(NM_001199828) chr1 152957607 P_DEgenes ExpMeth 24 exon (NM_001199828,chr1 153330230 P_DEgenes ExpMeth 25 promoter-TSS (NM_002965) chr274119341 P_DEgenes ExpMeth 26 promoter-TSS (NM_001199893) chr2 74119978P_DEgenes ExpMeth 27 promoter-TSS (NM_001199893) chr2 74119994 P_DEgenesExpMeth 28 promoter-TSS (NM_001199893) chr2 74120006 P_DEgenes ExpMeth29 promoter-TSS (NM_001199893) chr2 74120009 P_DEgenes ExpMeth 30promoter-TSS (NM_001199893) chr2 74120035 P_DEgenes ExpMeth 31promoter-TSS (NM_001199893) chr2 95940101 P_DEgenes ExpMeth 32promoter-TSS (NM_001165978) chr2 95940121 P_DEgenes ExpMeth 33promoter-TSS (NM_001165978) chr2 95940140 P_DEgenes ExpMeth 34promoter-TSS (NM_001165978) chr2 95940145 P_DEgenes ExpMeth 35promoter-TSS (NM_001165978) chr2 95940149 P_DEgenes ExpMeth 36promoter-TSS (NM_001165978) chr2 95940627 P_DEgenes ExpMeth 37 intron(NM_001165977, chr2 95943464 P_DEgenes ExpMeth 38 intron (NM_001165977,chr2 95945514 P_DEgenes ExpMeth 39 exon (NM_001165978, chr2 95954155P_DEgenes ExpMeth 40 exon (NM_001165978, chr2 95954163 P_DEgenes ExpMeth41 exon (NM_001165978, chr2 169921199 P_DEgenes ExpMeth 42 Intergenicchr2 169923445 P_DEgenes ExpMeth 43 promoter-TSS (NM_001289763) chr2169923487 P_DEgenes ExpMeth 44 promoter-TSS (NM_001289763) chr2169925966 P_DEgenes ExpMeth 45 5′ UTR chr2 169925972 P_DEgenes ExpMeth46 5′ UTR chr2 169925986 P_DEgenes ExpMeth 47 5′ UTR chr2 169928910P_DEgenes ExpMeth 48 promoter-TSS (NM_001142270) chr2 169937517P_DEgenes ExpMeth 49 promoter-TSS (NM_001142271) chr2 177001240P_DEgenes ExpMeth 50 promoter-TSS (NR_148241) chr2 177001585 P_DEgenesExpMeth 51 non-coding (NR_038435, chr2 177015022 P_DEgenes ExpMeth 52promoter-TSS (NR_029609) chr2 177025519 P_DEgenes ExpMeth 53 intron(NM_006898, chr2 177028705 P_DEgenes ExpMeth 54 5′ UTR chr2 182545174P_DEgenes ExpMeth 55 promoter-TSS (NR_146176) chr2 182545503 P_DEgenesExpMeth 56 promoter-TSS (NR_146176) chr2 219696414 P_DEgenes ExpMeth 57promoter-TSS (NM_017431) chr2 219696424 P_DEgenes ExpMeth 58promoter-TSS (NM_017431) chr2 219696426 P_DEgenes ExpMeth 59promoter-TSS (NM_017431) chr2 219696439 P_DEgenes ExpMeth 60promoter-TSS (NM_017431) chr2 219696709 P_DEgenes ExpMeth 61promoter-TSS (NM_017431) chr2 223916432 P_DEgenes ExpMeth 62promoter-TSS (NM_080671) chr2 223916762 P_DEgenes ExpMeth 63 5′ UTR chr2223916818 P_DEgenes ExpMeth 64 exon (NM_080671, chr2 233924577 P_DEgenesExpMeth 65 promoter-TSS (NM_005541) chr2 233924962 P_DEgenes ExpMeth 66promoter-TSS (NM_005541) chr2 233925089 P_DEgenes ExpMeth 67 exon(NM_005541, chr2 233940872 P_DEgenes ExpMeth 68 intron (NM_001017915,chr2 233985212 P_DEgenes ExpMeth 69 intron (NM_001017915, chr2 233986826P_DEgenes ExpMeth 70 exon (NM_005541, chr2 234053819 P_DEgenes ExpMeth71 intron (NM_001017915, chr2 234054695 P_DEgenes ExpMeth 72 intron(NM_001017915, chr2 234070270 P_DEgenes ExpMeth 73 exon (NM_005541, chr2234070335 P_DEgenes ExpMeth 74 exon (NM_005541, chr2 234072847 P_DEgenesExpMeth 75 intron (NM_001017915, chr2 234078106 P_DEgenes ExpMeth 76intron (NM_001017915, chr2 234078567 P_DEgenes ExpMeth 77 intron(NM_001017915, chr2 234078920 P_DEgenes ExpMeth 78 intron (NM_001017915,chr2 234103983 P_DEgenes ExpMeth 79 exon (NM_005541, chr2 234113188P_DEgenes ExpMeth 80 exon (NM_005541, chr3 12837871 P_DEgenes ExpMeth 81promoter-TSS (NM_001162499) chr3 12838071 P_DEgenes ExpMeth 82promoter-TSS (NM_001162499) chr3 12838079 P_DEgenes ExpMeth 83promoter-TSS (NM_001162499) chr3 12848532 P_DEgenes ExpMeth 84 intron(NM_012298, chr3 12868845 P_DEgenes ExpMeth 85 exon (NM_001162499, chr342726911 P_DEgenes ExpMeth 86 promoter-TSS (NM_152393) chr3 111717411P_DEgenes ExpMeth 87 promoter-TSS (NM_013259) chr3 111717486 P_DEgenesExpMeth 88 promoter-TSS (NM_013259) chr3 111717542 P_DEgenes ExpMeth 89promoter-TSS (NM_013259) chr3 111717936 P_DEgenes ExpMeth 90promoter-TSS (NM_001008273) chr3 111718095 P_DEgenes ExpMeth 91 5′ UTRchr3 111719270 P_DEgenes ExpMeth 92 intron (NM_001008273, chr3 111719519P_DEgenes ExpMeth 93 exon (NM_013259, chr3 128200821 P_DEgenes ExpMeth94 intron (NM_001145661, chr3 128206659 P_DEgenes ExpMeth 95promoter-TSS (NM_001145662) chr3 128207273 P_DEgenes ExpMeth 96promoter-TSS (NM_001145662) chr3 128209391 P_DEgenes ExpMeth 97 intron(NR_125398, chr3 128211916 P_DEgenes ExpMeth 98 promoter-TSS (NM_032638)chr3 128211928 P_DEgenes ExpMeth 99 promoter-TSS (NM_032638) chr3150481064 P_DEgenes ExpMeth 100 promoter-TSS (NM_005067) chr3 150481118P_DEgenes ExpMeth 101 promoter-TSS (NM_005067) chr3 150481164 P_DEgenesExpMeth 102 promoter-TSS (NM_005067) chr3 151154610 P_DEgenes ExpMeth103 TTS (NM_053002) chr3 151158459 P_DEgenes ExpMeth 104 promoter-TSS(NM_001178145) chr3 151158468 P_DEgenes ExpMeth 105 promoter-TSS(NM_001178145) chr3 151160838 P_DEgenes ExpMeth 106 exon (NM_178822,chr3 151176397 P_DEgenes ExpMeth 107 promoter-TSS (NM_178822) chr3181429614 P_DEgenes ExpMeth 108 promoter-TSS (NM_003106) chr3 181429622P_DEgenes ExpMeth 109 promoter-TSS (NM_003106) chr3 185782249 P_DEgenesExpMeth 110 intron (NM_004454, chr3 185783659 P_DEgenes ExpMeth 111 exon(NM_004454, chr3 185796794 P_DEgenes ExpMeth 112 intron (NM_004454, chr3185797595 P_DEgenes ExpMeth 113 exon (NM_004454, chr3 185823179P_DEgenes ExpMeth 114 exon (NM_004454, chr3 185823413 P_DEgenes ExpMeth115 intron (NM_004454, chr3 185823631 P_DEgenes ExpMeth 116 5′ UTR chr3185826233 P_DEgenes ExpMeth 117 intron (NM_004454, chr3 185826239P_DEgenes ExpMeth 118 intron (NM_004454, chr3 185826364 P_DEgenesExpMeth 119 intron (NM_004454, chr3 185826618 P_DEgenes ExpMeth 120intron (NM_004454, chr3 185826688 P_DEgenes ExpMeth 121 promoter-TSS(NM_004454) chr3 185826770 P_DEgenes ExpMeth 122 promoter-TSS(NM_004454) chr3 185826801 P_DEgenes ExpMeth 123 promoter-TSS(NM_004454) chr3 185828007 P_DEgenes ExpMeth 124 Intergenic chr3187086020 P_DEgenes ExpMeth 125 promoter-TSS (NM_022147) chr4 6694696P_DEgenes ExpMeth 126 promoter-TSS (NM_005980) chr4 6695505 P_DEgenesExpMeth 127 promoter-TSS (NM_005980) chr4 38796154 P_DEgenes ExpMeth 128Intergenic chr4 38805897 P_DEgenes ExpMeth 129 5′ UTR chr4 38806310P_DEgenes ExpMeth 130 promoter-TSS (NM_003263) chr4 38806312 P_DEgenesExpMeth 131 promoter-TSS (NM_003263) chr4 38806340 P_DEgenes ExpMeth 132promoter-TSS (NM_003263) chr4 38806372 P_DEgenes ExpMeth 133promoter-TSS (NM_003263) chr4 38806437 P_DEgenes ExpMeth 134promoter-TSS (NM_003263) chr4 38807054 P_DEgenes ExpMeth 135promoter-TSS (NM_003263) chr4 38807099 P_DEgenes ExpMeth 136promoter-TSS (NM_003263) chr4 38858338 P_DEgenes ExpMeth 137promoter-TSS (NM_006068) chr4 41258330 P_DEgenes ExpMeth 138promoter-TSS (NM_004181) chr4 41258686 P_DEgenes ExpMeth 139promoter-TSS (NM_004181) chr4 41258750 P_DEgenes ExpMeth 140promoter-TSS (NM_004181) chr4 41258825 P_DEgenes ExpMeth 141promoter-TSS (NM_004181) chr4 41258828 P_DEgenes ExpMeth 142promoter-TSS (NM_004181) chr4 41258849 P_DEgenes ExpMeth 143promoter-TSS (NM_004181) chr4 41258850 P_DEgenes ExpMeth 144promoter-TSS (NM_004181) chr4 41258857 P_DEgenes ExpMeth 145promoter-TSS (NM_004181) chr4 41258862 P_DEgenes ExpMeth 146promoter-TSS (NM_004181) chr4 41258863 P_DEgenes ExpMeth 147promoter-TSS (NM_004181) chr4 41262556 P_DEgenes ExpMeth 148 intron(NM_004181, chr4 41263656 P_DEgenes ExpMeth 149 exon (NM_004181, chr448899120 P_DEgenes ExpMeth 150 intron (NR_104589, chr4 48899765P_DEgenes ExpMeth 151 exon (NM_001014446, chr4 48908644 P_DEgenesExpMeth 152 promoter-TSS (NM_001014446) chr4 48908674 P_DEgenes ExpMeth153 promoter-TSS (NM_001014446) chr4 48908691 P_DEgenes ExpMeth 154promoter-TSS (NM_001014446) chr4 48908705 P_DEgenes ExpMeth 155promoter-TSS (NM_001014446) chr4 48908715 P_DEgenes ExpMeth 156promoter-TSS (NM_001014446) chr4 48908745 P_DEgenes ExpMeth 157promoter-TSS (NM_001014446) chr4 48908854 P_DEgenes ExpMeth 158promoter-TSS (NM_001014446) chr4 84030896 P_DEgenes ExpMeth 159promoter-TSS (NM_001130716) chr4 84035768 P_DEgenes ExpMeth 160promoter-TSS (NM_016619) chr4 84035789 P_DEgenes ExpMeth 161promoter-TSS (NM_016619) chr4 84035855 P_DEgenes ExpMeth 162promoter-TSS (NM_016619) chr4 84058128 P_DEgenes ExpMeth 163 Intergenicchr4 177158625 P_DEgenes ExpMeth 164 intron (NM_080874, chr4 177162727P_DEgenes ExpMeth 165 intron (NM_080874, chr4 177170609 P_DEgenesExpMeth 166 intron (NM_080874, chr4 177190273 P_DEgenes ExpMeth 167promoter-TSS (NM_080874) chr4 177198622 P_DEgenes ExpMeth 168 Intergenicchr5 102089585 P_DEgenes ExpMeth 169 promoter-TSS (NM_001319943) chr5102090271 P_DEgenes ExpMeth 170 promoter-TSS (NM_001364586) chr5102090387 P_DEgenes ExpMeth 171 promoter-TSS (NM_001364586) chr5102090918 P_DEgenes ExpMeth 172 promoter-TSS (NM_001364586) chr5102090947 P_DEgenes ExpMeth 173 promoter-TSS (NM_001364586) chr5102143661 P_DEgenes ExpMeth 174 promoter-TSS (NM_001364582) chr5102143667 P_DEgenes ExpMeth 175 promoter-TSS (NM_001364582) chr5102200141 P_DEgenes ExpMeth 176 intron (NM_001364582, chr5 102200848P_DEgenes ExpMeth 177 promoter-TSS (NM_138822) chr5 102200914 P_DEgenesExpMeth 178 promoter-TSS (NM_138822) chr5 102201083 P_DEgenes ExpMeth179 promoter-TSS (NM_138822) chr5 102201330 P_DEgenes ExpMeth 180promoter-TSS (NM_138822) chr5 102201341 P_DEgenes ExpMeth 181promoter-TSS (NM_138822) chr5 102201423 P_DEgenes ExpMeth 182promoter-TSS (NM_138822) chr5 102201427 P_DEgenes ExpMeth 183promoter-TSS (NM_138822) chr5 102201614 P_DEgenes ExpMeth 184 non-coding(NR_033440, chr5 102201661 P_DEgenes ExpMeth 185 non-coding (NR_033440,chr5 102201720 P_DEgenes ExpMeth 186 non-coding (NR_033440, chr5102202191 P_DEgenes ExpMeth 187 intron (NM_001364584, chr5 102231517P_DEgenes ExpMeth 188 intron (NR_033440, chr5 102285181 P_DEgenesExpMeth 189 exon (NM_001364582, chr5 102295601 P_DEgenes ExpMeth 190exon (NM_001364582, chr5 102325375 P_DEgenes ExpMeth 191 intron(NM_001364591, chr5 102343057 P_DEgenes ExpMeth 192 intron(NM_001364584, chr5 102343146 P_DEgenes ExpMeth 193 exon (NM_001364582,chr5 102343163 P_DEgenes ExpMeth 194 exon (NM_001364582, chr5 102343173P_DEgenes ExpMeth 195 exon (NM_001364582, chr6 34523991 P_DEgenesExpMeth 196 promoter-TSS (NM_001252294) chr6 34524010 P_DEgenes ExpMeth197 promoter-TSS (NM_001252294) chr6 112451090 P_DEgenes ExpMeth 198exon (NM_002290, chr6 112451261 P_DEgenes ExpMeth 199 intron(NM_001105206, chr6 112460378 P_DEgenes ExpMeth 200 exon (NM_002290,chr6 112486266 P_DEgenes ExpMeth 201 exon (NM_002290, chr6 112500604P_DEgenes ExpMeth 202 intron (NM_001105206, chr6 112512866 P_DEgenesExpMeth 203 exon (NM_002290, chr6 112512903 P_DEgenes ExpMeth 204 exon(NM_002290, chr6 112512913 P_DEgenes ExpMeth 205 exon (NM_002290, chr6112537550 P_DEgenes ExpMeth 206 exon (NM_002290, chr6 112537855P_DEgenes ExpMeth 207 intron (NM_001105206, chr6 112575587 P_DEgenesExpMeth 208 promoter-TSS (NM_002290) chr6 112575640 P_DEgenes ExpMeth209 promoter-TSS (NM_002290) chr6 112575674 P_DEgenes ExpMeth 210promoter-TSS (NM_002290) chr6 112575680 P_DEgenes ExpMeth 211promoter-TSS (NM_002290) chr6 112575690 P_DEgenes ExpMeth 212promoter-TSS (NM_002290) chr6 112575702 P_DEgenes ExpMeth 213promoter-TSS (NM_002290) chr6 112575749 P_DEgenes ExpMeth 214promoter-TSS (NM_002290) chr6 112575812 P_DEgenes ExpMeth 215promoter-TSS (NM_002290) chr6 112575817 P_DEgenes ExpMeth 216promoter-TSS (NM_002290) chr6 112575824 P_DEgenes ExpMeth 217promoter-TSS (NM_002290) chr6 112576041 P_DEgenes ExpMeth 218promoter-TSS (NM_002290) chr7 148508815 P_DEgenes ExpMeth 219 intron(NM_004456, chr7 148580501 P_DEgenes ExpMeth 220 promoter-TSS(NM_001203249) chr7 148581151 P_DEgenes ExpMeth 221 promoter-TSS(NM_001203249) chr7 148581237 P_DEgenes ExpMeth 222 promoter-TSS(NM_001203247) chr7 148581240 P_DEgenes ExpMeth 223 promoter-TSS(NM_001203247) chr7 148581270 P_DEgenes ExpMeth 224 promoter-TSS(NM_001203247) chr7 148581275 P_DEgenes ExpMeth 225 promoter-TSS(NM_001203247) chr7 148581279 P_DEgenes ExpMeth 226 promoter-TSS(NM_001203247) chr7 148581313 P_DEgenes ExpMeth 227 promoter-TSS(NM_001203247) chr8 17169082 P_DEgenes ExpMeth 228 intron (NM_004686,chr8 17169272 P_DEgenes ExpMeth 229 intron (NM_004686, chr8 17206466P_DEgenes ExpMeth 230 exon (NM_004686, chr8 17206646 P_DEgenes ExpMeth231 intron (NM_004686, chr8 17206894 P_DEgenes ExpMeth 232 intron(NM_004686, chr8 17270716 P_DEgenes ExpMeth 233 promoter-TSS (NM_004686)chr8 17270736 P_DEgenes ExpMeth 234 promoter-TSS (NM_004686) chr817270937 P_DEgenes ExpMeth 235 promoter-TSS (NM_004686) chr8 53045604P_DEgenes ExpMeth 236 intron (NM_001352827, chr8 53045678 P_DEgenesExpMeth 237 intron (NM_001352827, chr8 53050272 P_DEgenes ExpMeth 238intron (NM_001352827, chr8 53130239 P_DEgenes ExpMeth 239 5′ UTR chr85313028 P_DEgenes ExpMeth 240 5′ UTR chr8 53130282 P_DEgenes ExpMeth 2415′ UTR chr8 53134555 P_DEgenes ExpMeth 242 intron (NM_001352838, chr853159124 P_DEgenes ExpMeth 243 non-coding (NR_148195, chr8 53160986P_DEgenes ExpMeth 244 non-coding (NR_148196, chr8 53161872 P_DEgenesExpMeth 245 promoter-TSS (NM_001352856) chr8 53166808 P_DEgenes ExpMeth246 5′ UTR chr8 53322203 P_DEgenes ExpMeth 247 promoter-TSS(NM_001352883) chr8 53322209 P_DEgenes ExpMeth 248 promoter-TSS(NM_001352883) chr8 53322216 P_DEgenes ExpMeth 249 promoter-TSS(NM_001352883) chr8 53322232 P_DEgenes ExpMeth 250 promoter-TSS(NM_001352883) chr8 53322252 P_DEgenes ExpMeth 251 promoter-TSS(NM_001352826) chr8 53322265 P_DEgenes ExpMeth 252 promoter-TSS(NM_001352826) chr8 53322339 P_DEgenes ExpMeth 253 promoter-TSS(NM_001352826) chr8 53322342 P_DEgenes ExpMeth 254 promoter-TSS(NM_001352826) chr8 53322405 P_DEgenes ExpMeth 255 promoter-TSS(NM_001352826) chr8 53373419 P_DEgenes ExpMeth 256 Intergenic chr8104152838 P_DEgenes ExpMeth 257 promoter-TSS (NM_001024372) chr8104152841 P_DEgenes ExpMeth 258 promoter-TSS (NM_001024372) chr8104152887 P_DEgenes ExpMeth 259 promoter-TSS (NM_001024372) chr8104153026 P_DEgenes ExpMeth 260 TTS (NR_145429) chr8 104165267 P_DEgenesExpMeth 261 intron (NM_001024372, chr8 104220320 P_DEgenes ExpMeth 262intron (NM_001364874, chr8 104225459 P_DEgenes ExpMeth 263 intron(NM_001364874, chr8 104225539 P_DEgenes ExpMeth 264 intron(NM_001364874, chr10 69597717 P_DEgenes ExpMeth 265 5′ UTR chr1069597721 P_DEgenes ExpMeth 266 5′ UTR chr10 69597754 P_DEgenes ExpMeth267 promoter-TSS (NM_021800) chr10 69597822 P_DEgenes ExpMeth 268promoter-TSS (NM_021800) chr10 69597824 P_DEgenes ExpMeth 269promoter-TSS (NM_021800) chr10 88428106 P_DEgenes ExpMeth 270promoter-TSS (NM_001080116) chr10 88428270 P_DEgenes ExpMeth 271promoter-TSS (NM_001080116) chr10 88428326 P_DEgenes ExpMeth 272 5′ UTRchr10 88428328 P_DEgenes ExpMeth 273 5′ UTR chr10 88428349 P_DEgenesExpMeth 274 exon (NM_001080116, chr10 88478387 P_DEgenes ExpMeth 275exon (NM_007078, chr10 92680933 P_DEgenes ExpMeth 276 promoter-TSS(NM_014391) chr11 60869767 P_DEgenes ExpMeth 277 promoter-TSS(NM_014207) chr11 60869881 P_DEgenes ExpMeth 278 promoter-TSS(NM_014207) chr11 67350966 P_DEgenes ExpMeth 279 promoter-TSS(NM_000852) chr11 67351113 P_DEgenes ExpMeth 280 5′ UTR chr11 67351193P_DEgenes ExpMeth 281 5′ UTR chr11 67351495 P_DEgenes ExpMeth 282 intron(NM_000852, chr11 67351496 P_DEgenes ExpMeth 283 intron (NM_000852,chr11 67351505 P_DEgenes ExpMeth 284 exon (NM_000852, chr11 67351826P_DEgenes ExpMeth 285 intron (NM_000852, chr11 67352166 P_DEgenesExpMeth 286 intron (NM_000852, chr11 67353475 P_DEgenes ExpMeth 287 exon(NM_000852, chr11 87908501 P_DEgenes ExpMeth 288 promoter-TSS(NM_022337) chr11 87908502 P_DEgenes ExpMeth 289 promoter-TSS(NM_022337) chr11 87908535 P_DEgenes ExpMeth 290 promoter-TSS(NM_022337) chr11 112831897 P_DEgenes ExpMeth 291 promoter-TSS(NM_001242608) chr11 112831990 P_DEgenes ExpMeth 292 promoter-TSS(NM_001242608) chr11 112832024 P_DEgenes ExpMeth 293 promoter-TSS(NM_001242608) chr11 112832047 P_DEgenes ExpMeth 294 promoter-TSS(NM_001242608) chr11 112832057 P_DEgenes ExpMeth 295 promoter-TSS(NM_001242608) chr11 112832058 P_DEgenes ExpMeth 296 promoter-TSS(NM_001242608) chr11 112832059 P_DEgenes ExpMeth 297 promoter-TSS(NM_001242608) chr11 112832061 P_DEgenes ExpMeth 298 promoter-TSS(NM_001242608) chr11 112832102 P_DEgenes ExpMeth 299 promoter-TSS(NM_001242608) chr11 113001316 P_DEgenes ExpMeth 300 intron (NM_181351,chr11 113003550 P_DEgenes ExpMeth 301 intron (NM_181351, chr11 113067815P_DEgenes ExpMeth 302 intron (NM_181351, chr11 113072979 P_DEgenesExpMeth 303 intron (NM_181351, chr11 113072998 P_DEgenes ExpMeth 304intron (NM_181351, chr11 113102002 P_DEgenes ExpMeth 305 intron(NM_001242607, chr11 113102884 P_DEgenes ExpMeth 306 exon (NM_001242608,chr11 113102947 P_DEgenes ExpMeth 307 exon (NM_001242608, chr11113103415 P_DEgenes ExpMeth 308 exon (NM_001242608, chr11 113103417P_DEgenes ExpMeth 309 exon (NM_001242608, chr11 113103766 P_DEgenesExpMeth 310 intron (NM_181351, chr11 113103880 P_DEgenes ExpMeth 311exon (NM_001242608, chr11 113111129 P_DEgenes ExpMeth 312 intron(NM_001076682, chr11 113116730 P_DEgenes ExpMeth 313 intron(NM_001076682, chr11 113126572 P_DEgenes ExpMeth 314 exon (NM_001242608,chr11 113130713 P_DEgenes ExpMeth 315 intron (NM_181351, chr11 113130880P_DEgenes ExpMeth 316 exon (NM_001242608, chr11 113140591 P_DEgenesExpMeth 317 intron (NR_034101, chr11 113143642 P_DEgenes ExpMeth 318intron (NM_181351, chr11 133938720 P_DEgenes ExpMeth 319 promoter-TSS(NM_001205329) chr11 133938866 P_DEgenes ExpMeth 320 promoter-TSS(NM_032801) chr11 133938880 P_DEgenes ExpMeth 321 promoter-TSS(NM_032801) chr11 133996134 P_DEgenes ExpMeth 322 intron (NM_032801,chr11 134009435 P_DEgenes ExpMeth 323 intron (NM_032801, chr11 134017593P_DEgenes ExpMeth 324 intron (NM_032801, chr12 7022809 P_DEgenes ExpMeth325 promoter-TSS (NM_001975) chr12 7023391 P_DEgenes ExpMeth 326promoter-TSS (NM_001975) chr12 7023514 P_DEgenes ExpMeth 327promoter-TSS (NM_001975) chr12 7023602 P_DEgenes ExpMeth 328promoter-TSS (NM_001975) chr12 7023621 P_DEgenes ExpMeth 329promoter-TSS (NM_001975) chr12 7023653 P_DEgenes ExpMeth 330promoter-TSS (NM_001975) chr12 7023658 P_DEgenes ExpMeth 331promoter-TSS (NM_001975) chr12 7023661 P_DEgenes ExpMeth 332promoter-TSS (NM_001975) chr12 7023674 P_DEgenes ExpMeth 333promoter-TSS (NM_001975) chr12 7024271 P_DEgenes ExpMeth 334 TTS(NM_001135217) chr12 7026393 P_DEgenes ExpMeth 335 intron (NM_001975,chr12 7028638 P_DEgenes ExpMeth 336 exon (NM_001975, chr12 7030644P_DEgenes ExpMeth 337 exon (NM_001975, chr12 7031052 P_DEgenes ExpMeth338 intron (NM_001975, chr12 24983162 P_DEgenes ExpMeth 339 intron(NM_001178092, chr12 25055130 P_DEgenes ExpMeth 340 promoter-TSS(NM_001178094) chr12 25055222 P_DEgenes ExpMeth 341 promoter-TSS(NM_001178094) chr12 25055909 P_DEgenes ExpMeth 342 promoter-TSS(NM_001178094) chr12 25101877 P_DEgenes ExpMeth 343 promoter-TSS(NM_001178091) chr12 25101883 P_DEgenes ExpMeth 344 promoter-TSS(NM_001178091) chr12 25101895 P_DEgenes ExpMeth 345 promoter-TSS(NM_001178091) chr12 25101920 P_DEgenes ExpMeth 346 promoter-TSS(NM_001178091) chr12 25102293 P_DEgenes ExpMeth 347 promoter-TSS(NM_001178091) chr12 25173836 P_DEgenes ExpMeth 348 intron(NM_001321724, chr12 25186593 P_DEgenes ExpMeth 349 intron(NM_001321724, chr12 25188314 P_DEgenes ExpMeth 350 intron(NM_001321724, chr12 25205089 P_DEgenes ExpMeth 351 promoter-TSS(NM_001366542) chr12 25205105 P_DEgenes ExpMeth 352 promoter-TSS(NM_001366542) chr12 25205106 P_DEgenes ExpMeth 353 promoter-TSS(NM_001366542) chr12 25205346 P_DEgenes ExpMeth 354 promoter-TSS(NM_001204126) chr12 25205421 P_DEgenes ExpMeth 355 promoter-TSS(NM_001204126) chr12 25205476 P_DEgenes ExpMeth 356 promoter-TSS(NM_001204126) chr12 25205499 P_DEgenes ExpMeth 357 promoter-TSS(NM_001204126) chr12 25205534 P_DEgenes ExpMeth 358 promoter-TSS(NM_001204126) chr12 25205574 P_DEgenes ExpMeth 359 promoter-TSS(NM_001204126) chr12 25205779 P_DEgenes ExpMeth 360 TTS (NM_001321724)chr12 25228574 P_DEgenes ExpMeth 361 intron (NR_159367, chr12 25242608P_DEgenes ExpMeth 362 exon (NM_001366542, chr12 25249767 P_DEgenesExpMeth 363 exon (NM_001366542, chr12 25249792 P_DEgenes ExpMeth 364exon (NM_001366542, chr12 25257163 P_DEgenes ExpMeth 365 intron(NR_159367, chr12 66582559 P_DEgenes ExpMeth 366 promoter-TSS(NM_001142523) chr12 66582875 P_DEgenes ExpMeth 367 promoter-TSS(NM_001142523) chr12 66582937 P_DEgenes ExpMeth 368 promoter-TSS(NM_001142523) chr12 70082891 P_DEgenes ExpMeth 369 promoter-TSS(NM_152439) chr12 70082956 P_DEgenes ExpMeth 370 promoter-TSS(NM_152439) chr12 70087752 P_DEgenes ExpMeth 371 intron (NM_001282615,chr12 70092965 P_DEgenes ExpMeth 372 promoter-TSS (NM_001282616) chr1270093015 P_DEgenes ExpMeth 373 promoter-TSS (NM_001282614) chr1270093024 P_DEgenes ExpMeth 374 promoter-TSS (NM_001282614) chr1270093031 P_DEgenes ExpMeth 375 promoter-TSS (NM_001282614) chr1270093041 P_DEgenes ExpMeth 376 promoter-TSS (NM_001282614) chr1270093044 P_DEgenes ExpMeth 377 promoter-TSS (NM_001282614) chr1270093075 P_DEgenes ExpMeth 378 promoter-TSS (NM_001282614) chr1270093096 P_DEgenes ExpMeth 379 promoter-TSS (NM_001282614) chr1270093156 P_DEgenes ExpMeth 380 promoter-TSS (NM_001282614) chr12103351364 P_DEgenes ExpMeth 381 promoter-TSS (NM_004316) chr13 102527544P_DEgenes ExpMeth 382 exon (NM_001321933, chr13 102568895 P_DEgenesExpMeth 383 promoter-TSS (NM_004115) chr13 103054024 P_DEgenes ExpMeth384 promoter-TSS (NM_175929) chr14 21994247 P_DEgenes ExpMeth 385non-coding (NR_111967, chr14 21994261 P_DEgenes ExpMeth 386 non-coding(NR_111967, chr14 21994534 P_DEgenes ExpMeth 387 promoter-TSS(NR_111967) chr14 22004936 P_DEgenes ExpMeth 388 non-coding (NR_111966,chr14 22004968 P_DEgenes ExpMeth 389 non-coding (NR_111966, chr1422005138 P_DEgenes ExpMeth 390 promoter-TSS (NM_001291446) chr1422005250 P_DEgenes ExpMeth 391 promoter-TSS (NR_111966) chr14 51448929P_DEgenes ExpMeth 392 intron (NM_015163, chr14 51453070 P_DEgenesExpMeth 393 intron (NM_015163, chr14 51454994 P_DEgenes ExpMeth 394intron (NM_015163, chr14 51561694 P_DEgenes ExpMeth 395 5′ UTR chr1451561947 P_DEgenes ExpMeth 396 5′ UTR chr14 51562679 P_DEgenes ExpMeth397 promoter-TSS (NM_015163) chr14 75988668 P_DEgenes ExpMeth 398promoter-TSS (NM_006399) chr14 75988698 P_DEgenes ExpMeth 399promoter-TSS (NM_006399) chr14 75988803 P_DEgenes ExpMeth 400promoter-TSS (NM_006399) chr14 93389325 P_DEgenes ExpMeth 401promoter-TSS (NM_001275) chr14 93389402 P_DEgenes ExpMeth 402promoter-TSS (NM_001275) chr14 93389421 P_DEgenes ExpMeth 403promoter-TSS (NM_001275) chr14 93389608 P_DEgenes ExpMeth 404 exon(NM_001275, chr14 93392346 P_DEgenes ExpMeth 405 intron (NM_001301690,chr14 93397922 P_DEgenes ExpMeth 406 exon (NM_001275, chr15 74465912P_DEgenes ExpMeth 407 promoter-TSS (NM_005545) chr15 74466371 P_DEgenesExpMeth 408 promoter-TSS (NM_201526) chr15 74466644 P_DEgenes ExpMeth409 promoter-TSS (NM_201526) chr15 74466742 P_DEgenes ExpMeth 410promoter-TSS (NM_201526) chr15 77285600 P_DEgenes ExpMeth 411 Intergenicchr15 77286921 P_DEgenes ExpMeth 412 promoter-TSS (NM_001321136) chr1577287326 P_DEgenes ExpMeth 413 promoter-TSS (NM_001321136) chr1577287363 P_DEgenes ExpMeth 414 promoter-TSS (NM_001321136) chr1577287365 P_DEgenes ExpMeth 415 promoter-TSS (NM_001321136) chr1577287367 P_DEgenes ExpMeth 416 promoter-TSS (NM_001321136) chr1577287372 P_DEgenes ExpMeth 417 promoter-TSS (NM_001321136) chr1577287413 P_DEgenes ExpMeth 418 promoter-TSS (NM_001321136) chr1577287603 P_DEgenes ExpMeth 419 non-coding (NR_135552, chr15 77287626P_DEgenes ExpMeth 420 non-coding (NR_135552, chr15 77287653 P_DEgenesExpMeth 421 exon (NM_001321137, chr15 77287660 P_DEgenes ExpMeth 422exon (NM_001321137, chr15 77287815 P_DEgenes ExpMeth 423 exon(NM_001321135, chr15 77308052 P_DEgenes ExpMeth 424 intron(NM_001321136, chr15 77310699 P_DEgenes ExpMeth 425 exon (NM_001321136,chr15 77319966 P_DEgenes ExpMeth 426 intron (NR_135552, chr15 77320584P_DEgenes ExpMeth 427 intron (NR_135552, chr15 77324558 P_DEgenesExpMeth 428 exon (NM_001321136, chr15 77327935 P_DEgenes ExpMeth 429intron (NR_135552, chr16 29674500 P_DEgenes ExpMeth 430 promoter-TSS(NM_003123) chr16 29690229 P_DEgenes ExpMeth 431 promoter-TSS(NR_134536) chr16 29690258 P_DEgenes ExpMeth 432 promoter-TSS(NR_134536) chr16 29690403 P_DEgenes ExpMeth 433 promoter-TSS(NR_134536) chr16 29707018 P_DEgenes ExpMeth 434 intron (NM_014298,chr16 31146861 P_DEgenes ExpMeth 435 promoter-TSS (NM_002773) chr1631146924 P_DEgenes ExpMeth 436 promoter-TSS (NM_002773) chr16 31146948P_DEgenes ExpMeth 437 promoter-TSS (NM_002773) chr16 31146983 P_DEgenesExpMeth 438 promoter-TSS (NM_002773) chr16 74710849 P_DEgenes ExpMeth439 intron (NM_152649, chr16 74712211 P_DEgenes ExpMeth 440 intron(NM_152649, chr16 74712746 P_DEgenes ExpMeth 441 exon (NM_152649, chr1674725267 P_DEgenes ExpMeth 442 intron (NM_152649, chr16 74734588P_DEgenes ExpMeth 443 promoter-TSS (NM_001142497) chr16 74734607P_DEgenes ExpMeth 444 promoter-TSS (NM_001142497) chr16 74734712P_DEgenes ExpMeth 445 promoter-TSS (NM_001142497) chr16 74734758P_DEgenes ExpMeth 446 promoter-TSS (NM_001142497) chr16 88713133P_DEgenes ExpMeth 447 exon (NM_000101, chr16 88716622 P_DEgenes ExpMeth448 intron (NM_000101, chr16 88717296 P_DEgenes ExpMeth 449 promoter-TSS(NM_000101) chr16 88717323 P_DEgenes ExpMeth 450 promoter-TSS(NM_000101) chr16 88717338 P_DEgenes ExpMeth 451 promoter-TSS(NM_000101) chr16 88717339 P_DEgenes ExpMeth 452 promoter-TSS(NM_000101) chr16 88717343 P_DEgenes ExpMeth 453 promoter-TSS(NM_000101) chr16 88717349 P_DEgenes ExpMeth 454 promoter-TSS(NM_000101) chr16 88717362 P_DEgenes ExpMeth 455 promoter-TSS(NM_000101) chr16 88717460 P_DEgenes ExpMeth 456 promoter-TSS(NM_000101) chr17 1665153 P_DEgenes ExpMeth 457 promoter-TSS (NM_002615)chr17 1665223 P_DEgenes ExpMeth 458 promoter-TSS (NM_002615) chr171665255 P_DEgenes ExpMeth 459 promoter-TSS (NM_002615) chr17 1665262P_DEgenes ExpMeth 460 promoter-TSS (NM_002615) chr17 1665306 P_DEgenesExpMeth 461 promoter-TSS (NM_002615) chr17 1666023 P_DEgenes ExpMeth 462promoter-TSS (NM_001329903) chr17 1669468 P_DEgenes ExpMeth 463 intron(NM_001329903, chr17 1673720 P_DEgenes ExpMeth 464 intron (NM_001329903,chr17 1674913 P_DEgenes ExpMeth 465 promoter-TSS (NM_001329905) chr171679644 P_DEgenes ExpMeth 466 intron (NM_001329903, chr17 27283357P_DEgenes ExpMeth 467 exon (NM_178860, chr17 27284731 P_DEgenes ExpMeth468 intron (NM_001098635, chr17 27287891 P_DEgenes ExpMeth 469 exon(NM_178860, chr17 27308510 P_DEgenes ExpMeth 470 exon (NM_178860, chr1727308790 P_DEgenes ExpMeth 471 exon (NM_178860, chr17 27332831 P_DEgenesExpMeth 472 5′ UTR chr17 27332981 P_DEgenes ExpMeth 473 promoter-TSS(NM_178860) chr17 27333063 P_DEgenes ExpMeth 474 promoter-TSS(NM_178860) chr17 27333216 P_DEgenes ExpMeth 475 promoter-TSS(NM_178860) chr17 27333358 P_DEgenes ExpMeth 476 promoter-TSS(NM_178860) chr17 62007774 P_DEgenes ExpMeth 477 intron (NM_001039933,chr17 62009521 P_DEgenes ExpMeth 478 promoter-TSS (NM_000626) chr1762009583 P_DEgenes ExpMeth 479 promoter-TSS (NM_000626) chr17 62009591P_DEgenes ExpMeth 480 promoter-TSS (NM_000626) chr17 62009596 P_DEgenesExpMeth 481 promoter-TSS (NM_000626) chr17 62009614 P_DEgenes ExpMeth482 promoter-TSS (NM_000626) chr17 76970778 P_DEgenes ExpMeth 483 exon(NM_005567, chr17 76970979 P_DEgenes ExpMeth 484 intron (NM_005567,chr17 76972138 P_DEgenes ExpMeth 485 exon (NM_005567, chr17 76973198P_DEgenes ExpMeth 486 intron (NM_005567, chr17 76973305 P_DEgenesExpMeth 487 intron (NM_005567, chr17 76975825 P_DEgenes ExpMeth 488promoter-TSS (NM_005567) chr17 76975857 P_DEgenes ExpMeth 489promoter-TSS (NM_005567) chr17 76975873 P_DEgenes ExpMeth 490promoter-TSS (NM_005567) chr17 76975890 P_DEgenes ExpMeth 491promoter-TSS (NM_005567) chr17 76975893 P_DEgenes ExpMeth 492promoter-TSS (NM_005567) chr17 76975900 P_DEgenes ExpMeth 493promoter-TSS (NM_005567) chr17 76975905 P_DEgenes ExpMeth 494promoter-TSS (NM_005567) chr17 76975909 P_DEgenes ExpMeth 495promoter-TSS (NM_005567) chr17 76975917 P_DEgenes ExpMeth 496promoter-TSS (NM_005567) chr17 76975929 P_DEgenes ExpMeth 497promoter-TSS (NM_005567) chr17 76976091 P_DEgenes ExpMeth 498promoter-TSS (NM_005567) chr18 25616449 P_DEgenes ExpMeth 499promoter-TSS (NM_001308176) chr18 25625460 P_DEgenes ExpMeth 500 intron(NM_001792, chr18 25677093 P_DEgenes ExpMeth 501 intron (NM_001792,chr18 25739161 P_DEgenes ExpMeth 502 intron (NM_001792, chr18 25757310P_DEgenes ExpMeth 503 promoter-TSS (NM_001792) chr18 31158479 P_DEgenesExpMeth 504 5′ UTR chr18 31158496 P_DEgenes ExpMeth 505 exon (NM_030632,chr18 31158505 P_DEgenes ExpMeth 506 exon (NM_030632, chr18 31158508P_DEgenes ExpMeth 507 exon (NM_030632, chr18 31158530 P_DEgenes ExpMeth508 exon (NM_030632, chr18 31158635 P_DEgenes ExpMeth 509 intron(NM_030632, chr18 31158746 P_DEgenes ExpMeth 510 intron (NM_030632,chr18 31185450 P_DEgenes ExpMeth 511 intron (NM_030632, chr18 31185451P_DEgenes ExpMeth 512 intron (NM_030632, chr18 31185458 P_DEgenesExpMeth 513 intron (NM_030632, chr18 31185463 P_DEgenes ExpMeth 514intron (NM_030632, chr18 31185472 P_DEgenes ExpMeth 515 intron(NM_030632, chr18 31185490 P_DEgenes ExpMeth 516 intron (NM_030632,chr18 31187471 P_DEgenes ExpMeth 517 exon (NM_030632, chr19 39989435P_DEgenes ExpMeth 518 promoter-TSS (NM_016941) chr19 39989507 P_DEgenesExpMeth 519 promoter-TSS (NM_016941) chr19 39989508 P_DEgenes ExpMeth520 promoter-TSS (NM_016941) chr19 46916741 P_DEgenes ExpMeth 521promoter-TSS (NM_032040) chr19 51358071 P_DEgenes ExpMeth 522promoter-TSS (NM_001030048) chr19 51358077 P_DEgenes ExpMeth 523promoter-TSS (NM_001030048) chr19 51358086 P_DEgenes ExpMeth 524promoter-TSS (NM_001030048) chr19 51358091 P_DEgenes ExpMeth 525promoter-TSS (NM_001030048) chr19 51358105 P_DEgenes ExpMeth 526promoter-TSS (NM_001030048) chr19 51358112 P_DEgenes ExpMeth 527promoter-TSS (NM_001030048) chr19 51358128 P_DEgenes ExpMeth 528promoter-TSS (NM_001030048) chr19 51360547 P_DEgenes ExpMeth 529 intron(NM_001030048, chr20 3210322 P_DEgenes ExpMeth 530 exon (NM_001174089,chr20 3211106 P_DEgenes ExpMeth 531 exon (NM_001174089, chr20 3218273P_DEgenes ExpMeth 532 promoter-TSS (NM_032034) chr20 3218712 P_DEgenesExpMeth 533 promoter-TSS (NM_032034) chr20 3219259 P_DEgenes ExpMeth 534promoter-TSS (NM_032034) chr20 3219736 P_DEgenes ExpMeth 535promoter-TSS (NM_001174089) chr20 5891976 P_DEgenes ExpMeth 536promoter-TSS (NM_001819) chr20 5892076 P_DEgenes ExpMeth 537promoter-TSS (NM_001819) chr20 5896044 P_DEgenes ExpMeth 538 intron(NM_001819, chr20 20348665 P_DEgenes ExpMeth 539 promoter-TSS(NM_002196) chr20 22565001 P_DEgenes ExpMeth 540 promoter-TSS(NM_021784) chr21 22565993 P_DEgenes ExpMeth 541 promoter-TSS(NM_153675) chr21 42839929 P_DEgenes ExpMeth 542 intron (NM_005656,chr21 42840664 P_DEgenes ExpMeth 543 intron (NM_005656, chr21 42878431P_DEgenes ExpMeth 544 intron (NM_005656, chr21 42879809 P_DEgenesExpMeth 545 promoter-TSS (NM_001135099) chr21 42879892 P_DEgenes ExpMeth546 promoter-TSS (NM_001135099) chr21 42879919 P_DEgenes ExpMeth 547promoter-TSS (NM_001135099) chr21 42879941 P_DEgenes ExpMeth 548promoter-TSS (NM_001135099) chr21 42879985 P_DEgenes ExpMeth 549promoter-TSS (NM_001135099) chr21 42879986 P_DEgenes ExpMeth 550promoter-TSS (NM_001135099) chr21 42902925 P_DEgenes ExpMeth 551Intergenic chr21 42902943 P_DEgenes ExpMeth 552 Intergenic chrX 49056535P_DEgenes ExpMeth 553 promoter-TSS (NM_003179) chrX 49056552 P_DEgenesExpMeth 554 promoter-TSS (NM_003179) chrX 49056554 P_DEgenes ExpMeth 555promoter-TSS (NM_003179) chrX 49056558 P_DEgenes ExpMeth 556promoter-TSS (NM_003179) chrX 49056618 P_DEgenes ExpMeth 557promoter-TSS (NM_003179) chrX 66764365 P_DEgenes ExpMeth 558promoter-TSS (NM_001348064) chrX 66764562 P_DEgenes ExpMeth 559 5′ UTRchrX 66764886 P_DEgenes ExpMeth 560 5′ UTR chrX 66788631 P_DEgenesExpMeth 561 5′ UTR chr1 202039153 CpG_2020 AUC_dBeta −1 1 Intergenicchr1 241206098 CpG_2020 AUC_dBeta 1 2 intron (NM_001350116, chr289530057 CpG_2020 AUC_dBeta −1 3 Intergenic chr3 193490472 CpG_2020AUC_dBeta −1 4 Intergenic chr5 1548487 CpG_2020 AUC_dBeta 1 5 Intergenicchr5 36521979 CpG_2020 AUC_dBeta −1 6 Intergenic chr5 39390555 CpG_2020AUC_dBeta −1 7 exon (NM_001244871, chr5 71146894 CpG_2020 AUC_dBeta 1 8Intergenic chr5 142194123 CpG_2020 AUC_dBeta 1 9 intron (NM_001349547,chr5 168573593 CpG_2020 AUC_dBeta −1 10 intron (NM_001271946, chr72006579 CpG_2020 AUC_dBeta −1 11 intron (NM_001304523, chr7 7799018CpG_2020 AUC_dBeta 1 12 intron (NM_001302350, chr7 127841628 CpG_2020AUC_dBeta 1 13 Intergenic chr7 129912398 CpG_2020 AUC_dBeta −1 14 intron(NM_001869, chr8 53499560 CpG_2020 AUC_dBeta 1 15 Intergenic chr861990390 CpG_2020 AUC_dBeta −1 16 Intergenic chr8 69087227 CpG_2020AUC_dBeta −1 17 intron (NM_024870, chr8 73479990 CpG_2020 AUC_dBeta 1 18exon (NM_004770, chr8 73849054 CpG_2020 AUC_dBeta 1 19 exon (NM_004770,chr8 133070961 CpG_2020 AUC_dBeta −1 20 intron (NM_001080399, chr8140727998 CpG_2020 AUC_dBeta 1 21 Intergenic chr8 141458926 CpG_2020AUC_dBeta −1 22 intron (NM_001160372, chr8 141994084 CpG_2020 AUC_dBeta1 23 UTR chr8 142367954 CpG_2020 AUC_dBeta 1 24 exon (NM_005293, chr8143395944 CpG_2020 AUC_dBeta 1 25 intron (NM_001363740, chr9 36748433CpG_2020 AUC_dBeta 1 26 Intergenic chr9 38437314 CpG_2020 AUC_dBeta 1 27Intergenic chr9 93792388 CpG_2020 AUC_dBeta 1 28 Intergenic chr9133769512 CpG_2020 AUC_dBeta 1 29 intron (NM_198180, chr9 134913164CpG_2020 AUC_dBeta −1 30 intron (NM_004269, chr9 138719304 CpG_2020AUC_dBeta 1 31 exon (NM_015447, chr14 100039425 CpG_2020 AUC_dBeta −1 32intron (NM_001144995, chr18 8660098 CpG_2020 AUC_dBeta −1 33 Intergenicchr18 14917016 CpG_2020 AUC_dBeta −1 34 Intergenic chr18 25442246CpG_2020 AUC_dBeta −1 35 Intergenic chr18 47258089 CpG_2020 AUC_dBeta 136 Intergenic chr20 20421462 CpG_2020 AUC_dBeta −1 37 intron (NM_020343,chr20 21563921 CpG_2020 AUC_dBeta −1 38 intron (NR_109880, chr2132546326 CpG_2020 AUC_dBeta 1 39 intron (NM_001353687, chr21 46885392CpG_2020 AUC_dBeta −1 40 intron (NM_130444, Distance Nearest start_hg19Detailed Annotation to TSS PromoterID Entrez ID Nearest Ensembl GeneName chr1 32237823 CpG −8133 NM_001294336 576 ENSG00000121753 ADGRB2chr1 43814069 intron (NM_005373,ntron 8 of 11) −10388 NM_001255 991ENSG00000117399 CDC20 chr1 151345023 promoter-TSS (NM_001258288) −5NM_001258288 8991 ENSG00000143416 SELENBP1 chr1 151810787 non-coding(NR_024237, exon 1 of 5) 143 NR_024237 100132111 C2CD4D-AS1 chr219561227 CpG −3134 NM_145260 130497 ENSG00000143867 OSR1 chr2 63283706non-coding (NR_130153, exon 5 of 5) 6004 NM_014562 5013 ENSG00000115507OTX1 chr2 177030050 intron (NM_006898, intron 2 of 3) 8154 NM_0068983232 ENSG00000128652 HOXD3 chr2 201450223 promoter-TSS (NM_001159) −204NM_001159 316 ENSG00000138356 AOX1 chr3 50378091 promoter-TSS(NM_170714) −61 NM_001206957 11186 ENSG00000068028 RASSF1 chr3 122296269promoter-TSS (NM_001113523) 77 NM_001113523 165631 ENSG00000173200PARP15 chr3 124860516 CpG 9652 NR_049815 100847039 ENSG00000264986MIR5092 chr5 958708 CpG 38480 NR_104615 100506688 ENSG00000215246LOC100506688 chr5 3187966 CpG 10271 NR_104617 102467074 ENSG00000249808LINC01377 chr5 180230667 promoter-TSS (NM_001364390) −79 NM_0011146204245 ENSG00000131446 MGAT1 chr6 13014771 CpG 1260 NM_001322314 221692ENSG00000112137 PHACTR1 chr6 15505245 intron (NM_004973, intron 9 of 17)157856 NR_036448 84062 ENSG00000047579 DTNBP1 chr6 26271093 exon(NM_003534, exon 1 of 1) 102 NM_003534 8355 ENSG00000273983 HIST1H3Gchr7 73245339 exon (NM_001305, exon 1 of 1) 403 NM_001305 1364ENSG00000189143 CLDN4 chr7 129425230 CpG −10777 NR_029615 406959ENSG00000207691 MIR183 chr8 56852048 intron (NM_002350, intron 1 of 12)−36805 NR_145767 109617001 ENSG00000199405 SNORA1B chr8 99960398 exon(NM_001286841, exon 2 of 5) 3869 NM_001142462 116039 ENSG00000164920OSR2 chr8 143625497 3′ UTR (NM_001702, exon 3 of 31) 70058 NM_01519323237 ENSG00000198576 ARC chr8 145104006 promoter-TSS (NR_158554) −66NR_158554 392275 SMPD5 chr10 6297648 Intergenic 52935 NM_001363545 5209ENSG00000170525 PFKFB3 chr10 22541895 non-coding (NR_038921, exon 1of 1) 1069 NR_038921 100130992 LOC100130992 chr11 393838 promoter-TSS(NM_007183) −95 NM_007183 11187 ENSG00000184363 PKP3 chr11 47416258 CpG−6074 NR_039707 100616222 ENSG00000264583 MIR4487 chr11 63974672 exon(NM_031471, exon 2 of 15) 706 NM_031471 83706 ENSG00000149781 FERMT3chr11 165408329 exon (NM_153253, exon 2 of 16) 906 NM_153253 6494ENSG00000213445 SIPA1 chr11 67204996 promoter-TSS (NM_005608) −41NM_005608 5790 ENSG00000213402 PTPRCAP chr11 69469526 TTS (NM_053056)13850 NM_053056 595 ENSG00000110092 CCND1 chr12 7060087 promoter-TSS(NM_080549) −56 NM_080549 5777 ENSG00000111679 PTPN6 chr12 53298578promoter-TSS (NM_002273) 65 NM_002273 3856 ENSG00000170421 KRT8 chr1295941769 promoter-TSS (NM_001278393) 85 NM_001278393 84101ENSG00000136014 USP44 chr12 107038917 intron (NM_213594, intron 3 of 17)39397 NR_038912 100505978 ENSG00000257711 LOC100505978 chr12 1247735685′ UTR (NM_181709, exon 1 of 3) 163 NM_181709 144347 ENSG00000178882RFLNA chr12 124950569 exon (NM_001077261, exon 7 of 48) 101328NM_001077261 9612 ENSG00000196498 NCOR2 chr16 1128589 promoter-TSS(NM_001053) −46 NR_027242 146336 ENSG00000261713 SSTR5-AS1 chr1726732020 exon (NM_001242366, exon 2 of 5) 983 NM_080669 113235ENSG00000076351 SLC46A1 chr17 41363402 promoter-TSS (NM_001291586) −82NM_001291588 113277 ENSG00000184988 TMEM106A chr17 43318510 exon(NM_005892, exon 14 of 27) −6537 NR_110326 100133991 ENSG00000267278MAP3K14-AS1 chr17 79251155 intron (NM_001037984, intron 6 of 15) 17802NM_001037984 124565 ENSG00000157637 SLC38A10 chr17 80358729 intron(NM_175902, intron 7 of 9) −17370 NM_001369488 284004 ENSG00000169660HEXD chr17 180847037 intron (NM_005993, intron 15 of 38) −49306NM_024702 79755 ENSG00000141579 ZNF750 chr19 2085186 intron (NM_130807,intron 1 of 4) 10940 NM_130807 126308 ENSG00000172081 MOB3A chr192588141 CpG −42278 NR_107004 102465838 ENSG00000277904 MIR7850 chr193179264 exon (NM_003775, exon 1 of 1) 829 NM_003775 8698 ENSG00000125910S1PR4 chr19 10735906 promoter-TSS (NM_001363611) −2 NM_001363611 57153ENSG00000129353 SLC44A2 chr19 15568260 exon (NM_001348028, exon 9 of 11)6888 NM_001348028 64926 ENSG00000105122 RASAL3 chr19 18872937 CpG 28961NM_000095 1311 ENSG00000105664 COMP chr19 35940325 intron (NM_005306,intron 2 of 2) 1350 NM_001370087 2867 ENSG00000126262 FFAR2 chr1942703509 non-coding (NR_073046, exon 5 of 5) 18098 NM_001270615 162989ENSG00000160570 DEDD2 chr22 48027541 promoter-TSS (NR_033377) 358NR_122046 284930 ENSG00000224271 LOC284930 chr1 2036183 intron(NM_001033582, intron 1 of 14) 308 NM_001033582 5590 ENSG00000067606PRKCZ chr1 2309984 non-coding (NR_125361, exon 7 of 7) 12787NM_001301060 79906 ENSG00000116151 MORN1 chr1 2379650MLT1C|LTR|ERVL-MaLR −19046 NM_001303012 9651 ENSG00000149527 PLCH2 chr19887711 Intergenic −3314 NM_001009566 22883 ENSG00000171603 CLSTN1 chr1119870187 promoter-TSS (NR_146623) −492 NR_146623 105378934ENSG00000232650 LINC01780 chr1 150122937 5′ UTR (NM_001304723, exon 1 of5) 316 NM_001304723 51177 ENSG00000023902 PLEKHO1 chr1 155034908promoter-TSS (NM_182689) −947 NM_182689 1945 ENSG00000243364 EFNA4 chr1156215318 exon (NM_024897, exon 3 of 7) 2274 NM_001272110 79957ENSG00000160781 PAQR6 chr1 205631878 exon (NM_033102, exon 3 of 5) 17597NM_033102 85414 ENSG00000158715 SLC45A3 chr1 234666987 non-coding(NR_038426, exon 1 of 3) 207 NR_038426 100506795 ENSG00000231768LINC01354 chr1 234908126 Intergenic −12567 NR_148962 100130249ENSG00000279261 PP2672 chr1 235805303 CpG 7497 NM_001098722 2786ENSG00000168243 GNG4 chr1 246939116 Intergenic −13561 NR_015422 149134LINC01341 chr2 3281230 intron (NM_001330530, intron 3 of 9) 100159NM_001330530 7260 ENSG00000032389 EIPR1 chr2 10567426 TTS (NM_134421)19290 NR_028374 100302743 ENSG00000206633 SNORA80B chr2 11796686 CpG13419 NM_012344 23620 ENSG00000169006 NTSR2 chr2 45237589 Intergenic−1218 NM_016932 10736 ENSG00000170577 SIX2 chr2 121432974 Intergenic−60258 NM_001371271 chr2 172952783 3′ UTR (NM_178120, exon 3 of 3) 3022NM_001038493 1745 ENSG00000144355 DLX1 chr2 240161519 intron (NM_006037,intron 2 of 26) −44619 NR_026664 85009 MGC16025 chr3 134125473 CpG−30947 NR_039951 100616281 ENSG00000284561 MIR4788 chr3 140813669 CpG43762 NM_080862 92369 ENSG00000175093 SPSB4 chr3 160167217 promoter-TSS(NM_173084) −28 NR_148401 100174949 ENSG00000248710 TRIM59-1FT80 chr3183891828 promoter-TSS (NM_001311198) −640 NM_001025205 1173ENSG00000161203 AP2M1 chr4 981385 3′ UTR (NM_213613, exon 4 of 4) 726NM_000203 3425 ENSG00000127415 IDUA chr4 1205814 non-coding (NR_104331,exon 3 of 6) 2124 NR_104331 285463 ENSG00000280927 CTBP1-AS chr4 7228168intron (NM_020777, intron 1 of 26) 34090 NM_020777 57537 ENSG00000184985SORCS2 chr5 92938049 Intergenic 18218 NR_031754 100313887ENSG00000284336 MIR2277 chr5 134827036 CpG −39437 NM_001099221 497189ENSG00000255833 TIFAB chr5 147162061 promoter-TSS (NM_001282282) −20NM_001270941 9832 ENSG00000176049 JAKMIP2 chr5 179588340 CpG 47572NM_175062 255426 ENSG00000146090 RASGEF1C chr6 40567217 CpG −12345NM_020737 57497 ENSG00000156564 LRFN2 chr6 170449317 Intergenic −26364NR_125878 102724511 LOC102724511 chr6 170578492 intron (NR_126021,intron 2 of 2) −2838 NR_104177 401289 LINC01624 chr7 214477MIR3|SINE|MIR 22107 NM_020223 56975 ENSG00000177706 FAM20C chr7 906626intron (NR_160282, intron 20 of 22) −9428 NM_015949 51608ENSG00000239857 GET4 chr7 921951 intron (NM_015949, intron 1 of 8) 5952NM_015949 51608 ENSG00000239857 GET4 chr7 2968216 CpG −84530 NM_0073532768 ENSG00000146535 GNA12 chr7 50628618 promoter-TSS (NM_001242889)−125 NM_001242887 1644 ENSG00000132437 DDC chr7 129912387 intron(NM_001869, intron 4 of 10) 5942 NM_001869 1358 ENSG00000158516 CPA2chr7 151432920 5′ UTR (NM_001304527, exon 1 of 14) 176 NM_00136369851422 ENSG00000106617 PRKAG2 chr8 73848837 exon (NM_004770, exon 3 of 3)−72073 NM_003218 7013 ENSG00000147601 TERF1 chr8 93114050 CpG 1160NM_001198633 862 ENSG00000079102 RUNX1T1 chr10 670687 intron (NM_014974,intron 1 of 36) −3607 NR_147612 101930421 ENSG00000225140 LOC101930421chr10 123923781 intron (NM_001291878, intron 1 of 16) 838 NM_20686010579 ENSG00000138162 TACC2 chr11 20625892 intron (NM_004211, intron 3of 15) 5182 NM_004211 9152 ENSG00000165970 SLC6A5 chr11 61449637 intron(NM_006133, intron 1 of 19) 1955 NM_006133 747 ENSG00000134780 DAGLAchr11 62211890 CpG 25588 NM_003357 7356 ENSG00000149021 SCGB1A1 chr12104852255 intron (NM_018413, intron 1 of 2) 1675 NM_001173982 50515ENSG00000171310 CHST11 chr12 110172108 non-coding (NR_026661, exon 4 of4) 20647 NM_032829 84915 ENSG00000139438 FAM222A chr12 125578255 CpG28469 NM_023928 65985 ENSG00000081760 AACS chr14 91862713 intron(NM_001080414, intron 3 of 29) 21304 NM_001080414 440193 ENSG00000015133CCDC88C chr14 95693684 intron (NM_024734, intron 2 of 12) −69536NM_030621 23405 ENSG00000100697 DICER1 chr14 101157815 Intergenic 34478NR_024096 283601 ENSG00000196273 LINC00523 chr15 89921572 CpG 599NR_015411 254559 ENSG00000255571 MIR9-3HG chr15 89959557 CpG 16566NR_160724 105371031 LOC105371031 chr15 99194331 promoter-TSS (NR_126453)−78 NR_126453 104472848 IRAIN chr16 1195273 Intergenic −7596 NM_0210988912 ENSG00000196557 CACNA1H chr16 29324459 intron (NR_002939, intron 2of 8) 11078 NR_002939 440352 SNX29P2 chr17 59480574 CpG-10965 3773NM_005994 6909 ENSG00000121068 TBX2 chr17 60827102 intron (NM_001288779,intron 4 of 11) 43797 NR_147886 105371855 ENSG00000265702 LOC105371855chr17 71744333 TTS (NR_027146) 10686 NM_001278587 100134391 LOC100134391chr17 72350254 exon (NM_153209, exon 18 of 20) 7475 NM_001080466 388419ENSG00000204347 BTBD17 chr17 73996145 promoter-TSS (NR_130467).2 −653NM_001258 1018 ENSG00000250506 CDK3 chr17 76355046 5′ UTR (NM_003955,exon 2 of 2) 943 NM_003955 9021 ENSG00000184557 SOCS3 chr17 78079381exon (NM_000152, exon 3 of 20) 4258 NM_001079803 2548 ENSG00000171298GAA chr17 79223965 TTS (NM_138570) 10472 NR_148426 284184ENSG00000224877 NDUFAF8 chr17 80019426 exon (NM_022156, exon 7 of 14)4103 NM_022156 64118 ENSG00000169718 DUS1L chr17 80052807 intron(NM_004104, intron 3 of 42) 3056 NM_004104 2194 ENSG00000169710 FASNchr17 80372675 intron (NR_033265, intron 2 of 9) −3379 NM_173620 284004ENSG00000169660 HEXD chr17 80832228 intron (NM_005993, intron 14 of 38)−34572 NM_024702 79755 ENSG00000141579 ZNF750 chr18 8659409 CpG 47782NR_120598 100287082 ENSG00000265962 GACAT2 chr18 13136240 Intergenic−82290 NM_181482 753 ENSG00000168675 LDLRAD4 chr19 2540807 CpG 64881NM_015675 4616 ENSG00000099860 GADD45B chr19 4566300 CpG −6843 NM_03210810501 ENSG00000167680 SEMA6B chr19 17790974 CpG 7794 NM_001080421 23025ENSG00000130477 UNC13A chr20 20432962 CpG 84447 NM_002196 3642ENSG00000173404 INSM1 chr20 51589516 5′ UTR (NM_173485, exon 1 of 3) 904NM_173485 128553 ENSG00000182463 TSHZ2 chr21 38077158 CpG 6051 NM_0050696493 ENSG00000159263 SIM2 chr21 43441927 promoter-TSS (NR_119385) 28NR_119385 150142 ENSG00000237232 ZNF295-AS1 chr1 2036220 promoter-TSS(NM_001033582) 67 NM_001033582 5590 ENSG00000067606 PRKCZ chr1 2036226promoter-TSS (NM_001033582) 73 NM_001033582 5590 ENSG00000067606 PRKCZchr1 2036232 promoter-TSS (NM_001033582) 79 NM_001033582 5590ENSG00000067606 PRKCZ chr1 2036252 promoter-TSS (NM_001033582) 99NM_001033582 5590 ENSG00000067606 PRKCZ chr1 2036395 intron(NM_001033582, intron 1 of 14) 242 NM_001033582 5590 ENSG00000067606PRKCZ chr1 3697617 3′ UTR (NM_020710, exon 7 of 7) 8268 NM_001163724388588 ENSG00000235169 SMIM1 chr1 3697629 3′ UTR (NM_020710, exon 7 of7) 8281 NM_001163724 388588 ENSG00000235169 SMIM1 chr1 3697639 3′ UTR(NM_020710, exon 7 of 7) 8290 NM_001163724 388588 ENSG00000235169 SMIM1chr1 3697648 3′ UTR (NM_020710, exon 7 of 7) 8299 NM_001163724 388588ENSG00000235169 SMIM1 chr1 3697654 exon (NM_020710, exon 7 of 7) 8307NM_001163724 388588 ENSG00000235169 SMIM1 chr1 3697667 exon (NM_020710,exon 7 of 7) 8318 NM_001163724 388588 ENSG00000235169 SMIM1 chr1 3697692exon (NM_020710, exon 7 of 7) 8343 NM_001163724 388588 ENSG00000235169SMIM1 chr1 3697702 exon (NM_020710, exon 7 of 7) 8353 NM_001163724388588 ENSG00000235169 SMIM1 chr1 6171653 MET1C|LTR|ERVL-MaLR 65707NM_001199863 8514 ENSG00000069424 KCNAB2 chr1 6171833 exon (NM_015557,exon 36 of 42) 65887 NM_001199863 8514 ENSG00000069424 KCNAB2 chr16171838 exon (NM_015557, exon 36 of 42) 65892 NM_001199863 8514ENSG00000069424 KCNAB2 chr1 6171845 exon (NM_015557, exon 36 of 42)65899 NM_001199863 8514 ENSG00000069424 KCNAB2 chr1 6171867 exon(NM_015557, exon 36 of 42) 65922 NM_001199863 8514 ENSG00000069424KCNAB2 chr1 9501648 Intergenic −12595 NR_104622 100506022ENSG00000284693 LINC02606 chr1 10696021 TTS (NM_001079843) 160680NM_001079843 54897 ENSG00000130940 CASZ1 chr1 10696065 TTS(NM_001079843) 160636 NM_001079843 54897 ENSG00000130940 CASZ1 chr118808323 exon (NM_152375, exon 1 of 1) 901 NM_152375 127707ENSG00000179023 KLHDC7A chr1 18808343 exon (NM_152375, exon 1 of 11 921NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18808439 exon (NM_152375,exon 1 of 1) 1017 NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18808469exon (NM_152375, exon 1 of 1) 1047 NM_152375 127707 ENSG00000179023KLHDC7A chr1 18808546 exon (NM_152375, exon 1 of 1) 1124 NM_152375127707 ENSG00000179023 KLHDC7A chr1 18808583 exon (NM_152375, exon 1of 1) 1161 NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18808621 exon(NM_152375, exon 1 of 1) 1199 NM_152375 127707 ENSG00000179023 KLHDC7Achr1 18808832 exon (NM_152375, exon 1 of 1) 1410 NM_152375 127707ENSG00000179023 KLHDC7A chr1 18808880 exon (NM_152375, exon 1 of 1) 1458NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18808929 exon (NM_152375,exon 1 of 1) 1509 NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18808938exon (NM_152375, exon 1 of 1) 1516 NM_152375 127707 ENSG00000179023KLHDC7A chr1 18808967 exon (NM_152375, exon 1 of 1) 1545 NM_152375127707 ENSG00000179023 KLHDC7A chr1 18808991 exon (NM_152375, exon 1of 1) 1569 NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18809009 exon(NM_152375, exon 1 of 1) 1587 NM_152375 127707 ENSG00000179023 KLHDC7Achr1 18809028 exon (NM_152375, exon 1 of 1) 1608 NM_152375 127707ENSG00000179023 KLHDC7A chr1 18809041 exon (NM_152375, exon 1 of 1) 1619NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18809052 exon (NM_152375,exon 1 of 1) 1630 NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18809058exon (NM_152375, exon 1 of 1) 1636 NM_152375 127707 ENSG00000179023KLHDC7A chr1 18809064 exon (NM_152375, exon 1 of 1) 1642 NM_152375127707 ENSG00000179023 KLHDC7A chr1 18809102 exon (NM_152375, exon 1of 1) 1680 NM_152375 127707 ENSG00000179023 KLHDC7A chr1 18809112 exon(NM_152375, exon 1 of 1) 1690 NM_152375 127707 ENSG00000179023 KLHDC7Achr1 18809126 exon (NM_152375, exon 1 of 1) 1704 NM_152375 127707ENSG00000179023 KLHDC7A chr1 18809494 exon (NM_152375, exon 1 of 1) 2072NM_152375 127707 ENSG00000179023 KLHDC7A chr1 20141125 exon (NM_019062,exon 1 of 1) 649 NM_019062 54546 ENSG00000178828 RNFI86 chr1 20141136exon (NM_019062, exon 1 of 1) 638 NM_019062 54546 ENSG00000178828 RNF186chr1 20141322 exon (NM_019062, exon 1 of 1) 452 NM_019062 54546ENSG00000178828 RNF186 chr1 20141344 exon (NM_019062, exon 1 of 1) 430NM_019062 54546 ENSG00000178828 RNF186 chr1 20141404 exon (NM_019062,exon 1 of 1) 370 NM_019062 54546 ENSG00000178828 RNF186 chr1 20141442exon (NM_019062, exon 1 of 1) 332 NM_019062 54546 ENSG00000178828 RNF186chr1 20141462 exon (NM_019062, exon 1 of 1) 312 NM_019062 54546ENSG00000178828 RNF186 chr1 22195529 intron (NM_005529, intron 33 of 96)56773 NM_001013693 401944 ENSG00000187942 LDLRAD2 chr1 32252163Intergenic −22224 NM_001294336 576 ENSG00000121753 ADGRB2 chr1 32252229Intergenic −22290 NM_001294336 576 ENSG00000121753 ADGRB2 chr1 32252239Intergenic −22300 NM_001294336 576 ENSG00000121753 ADGRB2 chr1 32252264Intergenic −22325 NM_001294336 576 ENSG00000121753 ADGRB2 chr1 32252425Intergenic −22486 NM_001294336 576 ENSG00000121753 ADGRB2 chr1 45103348intron (NM_001319957, intron 7 of 13) 33378 NR_145816 109623472 SNORD145chr1 45103390 intron (NM_001319957, intron 7 of 13) 33336 NR_145816109623472 SNORD145 chr1 45106491 intron (NM_001319957, intron 7 of 13)30235 NR_145816 109623472 SNORD145 chr1 156215343 exon (NM_001272106,exon 3 of 6) 2502 NM_001272104 79957 ENSG00000160781 PAQR6 chr1156215371 exon (NM_001272106, exon 3 of 6) 2474 NM_001272104 79957ENSG00000160781 PAQR6 chr1 156215401 exon (NM_001272106, exon 3 of 6)2444 NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215416 exon(NM_001272106, exon 3 of 6) 2429 NM_001272104 79957 ENSG00000160781PAQR6 chr1 156215430 exon (NM_001272106, exon 3 of 6) 2415 NM_00127210479957 ENSG00000160781 PAQR6 chr1 156215445 exon (NM_024897, exon 4 of 7)2400 NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215454 CpG 2391NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215491 CpG 2353NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215506 CpG 2338NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215520 CpG 2325NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215525 CpG 2320NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215530 CpG 2315NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215563 CpG 2282NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215590 exon (NM_024897,exon 3 of 7) 2253 NM_001272104 79957 ENSG00000160781 PAQR6 chr1156215601 exon (NM_024897, exon 3 of 7) 2244 NM_001272104 79957ENSG00000160781 PAQR6 chr1 156215708 non-coding (NR_073610, exon 3 of 7)2137 NM_001272104 79957 ENSG00000160781 PAQR6 chr1 156215720 non-coding(NR_073610, exon 3 of 7) 2125 NM_001272104 79957 ENSG00000160781 PAQR6chr1 156215726 non-coding (NR_073610, exon 3 of 7) 2117 NM_00127210479957 ENSG00000160781 PAQR6 chr1 156215737 non-coding (NR_073610, exon 3of 7) 2108 NM_001272104 79957 ENSG00000160781 PAQR6 chr1 203259747Intergenic 2923 NR_117098 100506775 ENSG00000231507 LINC01353 chr1203259757 Intergenic 2931 NR_117098 100506775 ENSG00000231507 LINC01353chr1 203259770 Intergenic 2944 NR_117098 100506775 ENSG00000231507LINC01353 chr1 203259836 Intergenic 3010 NR_117098 100506775ENSG00000231507 LINC01353 chr1 203259850 Intergenic 3024 NR_117098100506775 ENSG00000231507 LINC01353 chr1 203259921 Intergenic 3095NR_117098 100506775 ENSG00000231507 LINC01353 chr1 236311219 intron(NM_003272, intron 1 of 6) 5382 NM_003272 7107 ENSG00000077585 GPR137Bchr1 236311342 intron (NM_003272, intron 1 of 6) 5505 NM_003272 7107ENSG00000077585 GPR137B chr1 237129554 AluJb|SINE|Alu 38185 NM_001276687645745 ENSG00000244020 MT1HL1 chr1 237134163 AluSx1|SINE|Alu 33576NM_001276687 645745 ENSG00000244020 MT1HL1 chr1 237167480 TTS(NM_001276687) 259 NM_001276687 645745 ENSG00000244020 MT1HL1 chr1237194084 AluSx1|SINE|Alu −11398 NM_001035 6262 ENSG00000198626 RYR2chr1 237194093 AluSx1|SINE|Alu −11389 NM_001035 6262 ENSG00000198626RYR2 chr1 237194098 AluSx1|SINE|Alu −11384 NM_001035 6262ENSG00000198626 RYR2 chr1 237195314 LTR78|LTR|ERV1 −10168 NM_001035 6262ENSG00000198626 RYR2 chr1 237195411 LTR78|LTR|ERV1 −10071 NM_001035 6262ENSG00000198626 RYR2 chr1 237212336 intron (NM_001035, intron 1 of 104)6854 NM_001035 6262 ENSG00000198626 RYR2 chr1 237220609 AluSc8|SINE|Alu15127 NM_001035 6262 ENSG00000198626 RYR2 chr1 237220641 AluSc8|SINE|Alu15161 NM_001035 6262 ENSG00000198626 RYR2 chr1 237222098GC_rich|Low_complexity|Low_complexity 16616 NM_001035 6262ENSG00000198626 RYR2 chr1 237222106GC_rich|Low_complexity|Low_complexity 16624 NM_001035 6262ENSG00000198626 RYR2 chr1 237235121 MER52A|LTR|ERV1 29639 NM_001035 6262ENSG00000198626 RYR2 chr1 237235204 MER52A|LTR|ERV1 29722 NM_001035 6262ENSG00000198626 RYR2 chr1 237235522 MER52A|LTR|ERV1 30040 NM_001035 6262ENSG00000198626 RYR2 chr1 237235567 MER52A|LTR|ERV1 30086 NM_001035 6262ENSG00000198626 RYR2 chr1 237235607 FLAM_C|SINE|Alu 30125 NM_001035 6262ENSG00000198626 RYR2 chr1 237256273 intron (NM_001035, intron 1 of 104)50791 NM_001035 6262 ENSG00000198626 RYR2 chr1 237256316MER3|DNA|hAT-Charlie 50834 NM_001035 6262 ENSG00000198626 RYR2 chr1237265786 intron (NM_001035, intron 1 of 104) 60304 NM_001035 6262ENSG00000198626 RYR2 chr1 237265877 AluSz|SINE|Alu 60395 NM_001035 6262ENSG00000198626 RYR2 chr1 237267786 intron (NM_001035, intron 1 of 104)62304 NM_001035 6262 ENSG00000198626 RYR2 chr1 237267812 intron(NM_001035, intron 1 of 104) 62330 NM_001035 6262 ENSG00000198626 RYR2chr1 237267886 intron (NM_001035, intron 1 of 104) 62404 NM_001035 6262ENSG00000198626 RYR2 chr1 237306208 intron (NM_001035, intron 1 of 104)100726 NM_001035 6262 ENSG00000198626 RYR2 chr1 237306260 intron(NM_001035, intron 1 of 104) 100778 NM_001035 6262 ENSG00000198626 RYR2chr1 237343254 intron (NM_001035, intron 1 of 104) 137772 NM_001035 6262ENSG00000198626 RYR2 chr1 237359169 MIR|SINE|MIR 153687 NM_001035 6262ENSG00000198626 RYR2 chr1 237383690 MLT2B3|LTR|ERVL 178208 NM_0010356262 ENSG00000198626 RYR2 chr1 237392760 intron (NM_001035, intron 1 of104) 187278 NM_001035 6262 ENSG00000198626 RYR2 chr1 237408076LTR9|LTR|ERV1 202594 NM_001035 6262 ENSG00000198626 RYR2 chr1 237408091LTR9|LTR|ERV1 202609 NM_001035 6262 ENSG00000198626 RYR2 chr1 237473057LTR12C|LTR|ERV1 −161360 NR_039626 100616141 ENSG00000266262 MIR4428 chr1237473071 LTR12C|LTR|ERV1 −161346 NR_039626 100616141 ENSG00000266262MIR4428 chr1 237473091 LTR12C|LTR|ERV1 −161326 NR_039626 100616141ENSG00000266262 MIR4428 chr1 237473164 LTR12C|LTR|ERV1 −161253 NR_039626100616141 ENSG00000266262 MIR4428 chr1 237538162 intron (NM_001035,intron 7 of 104) −96255 NR_039626 100616141 ENSG00000266262 MIR4428 chr1237584276 AluSc8|SINE|Alu −50141 NR_039626 100616141 ENSG00000266262MIR4428 chr1 237661252 AluSz6|SINE|Alu 26835 NR_039626 100616141ENSG00000266262 MIR4428 chr1 237661262 AluSz6|SINE|Alu 26845 NR_039626100616141 ENSG00000266262 MIR4428 chr1 237661322 AluSz6|SINE|Alu 26905NR_039626 100616141 ENSG00000266262 MIR4428 chr1 237693526 AluY|SINE|Alu59109 NR_039626 100616141 ENSG00000266262 MIR4428 chr1 237693534AluY|SINE|Alu 59117 NR_039626 100616141 ENSG00000266262 MIR4428 chr1237699930 AluY|SINE|Alu 65513 NR_039626 100616141 ENSG00000266262MIR4428 chr1 237699938 AluY|SINE|Alu 65521 NR_039626 100616141ENSG00000266262 MIR4428 chr1 237699988 AluY|SINE|Alu 65571 NR_039626100616141 ENSG00000266262 MIR4428 chr1 237809365 AluY|SINE|Alu 174948NR_039626 100616141 ENSG00000266262 MIR4428 chr1 237815260 AluY|SINE|Alu180843 NR_039626 100616141 ENSG00000266262 MIR4428 chr1 241402493AluSc8|SINE|Alu 106923 NR_036069 100422856 ENSG00000265831 MIR3123 chr1241402516 AluSc8|SINE|Alu 106946 NR_036069 100422856 ENSG00000265831MIR3123 chr2 9248023 Intergenic −98869 NM_001135191 8853 ENSG00000151693ASAP2 chr2 9248368 Intergenic −98524 NM_001135191 8853 ENSG00000151693ASAP2 chr2 9248435 Intergenic −98457 NM_001135191 8853 ENSG00000151693ASAP2 chr2 9248469 Intergenic −98423 NM_001135191 8853 ENSG00000151693ASAP2 chr2 25299679 intron (NM_001319099, intron 1 of 22) 34349NM_001319099 22979 ENSG00000084710 EFR3B chr2 25299815 intron(NM_001319099, intron 1 of 22) 34485 NM_001319099 22979 ENSG00000084710EFR3B chr2 25299928 intron (NM_001319099, intron 1 of 22) 34598NM_001319099 22979 ENSG00000084710 EFR3B chr2 43102420 Intergenic −82699NM_012205 23498 ENSG00000162882 HAAO chr2 43107259 Intergenic −87538NM_012205 23498 ENSG00000162882 HAAO chr2 43107400 Intergenic −87679NM_012205 23498 ENSG00000162882 HAAO chr2 43107414 Intergenic −87693NM_012205 23498 ENSG00000162882 HAAO chr2 43107438 Intergenic −87717NM_012205 23498 ENSG00000162882 HAAO chr2 43107456 Intergenic −87735NM_012205 23498 ENSG00000162882 HAAO chr2 43107465 Intergenic −87744NM_012205 23498 ENSG00000162882 HAAO chr2 43107514 Intergenic −87793NM_012205 23498 ENSG00000162882 HAAO chr2 43107532 Intergenic −87811NM_012205 23498 ENSG00000162882 HAAO chr2 43107650 Intergenic −87929NM_012205 23498 ENSG00000162882 HAAO chr2 45235684 CpG 905 NM_01693210736 ENSG00000170577 SIX2 chr2 45235702 exon (NM_016932, exon 1 of 2)887 NM_016932 10736 ENSG00000170577 SEX2 chr2 45235710 exon (NM_016932,exon 1 of 2) 879 NM_016932 10736 ENSG00000170577 SEX2 chr2 207972376intron (NR_073108, intron 3 of 4) 2419 NR_036227 100423036ENSG00000253008 MIR2355 chr2 207972408 intron (NR_073108, intron 3 of 4)2387 NR_036227 100423036 ENSG00000253008 MIR2355 chr2 220509654Intergenic 17304 NM_005070 6508 ENSG00000114923 SLC4A3 chr2 220509693Intergenic 17343 NM_005070 6508 ENSG00000114923 SLC4A3 chr2 220509705Intergenic 17355 NM_005070 6508 ENSG00000114923 SLC4A3 chr2 220509776Intergenic 17426 NM_005070 6508 ENSG00000114923 SLC4A3 chr2 220509830Intergenic 17480 NM_005070 6508 ENSG00000114923 SLC4A3 chr2 241233035Intergenic −142043 NM_002081 2817 ENSG00000063660 GPC1 chr2 241233048Intergenic −142030 NM_002081 2817 ENSG00000063660 GPC1 chr2 241233055Intergenic −142023 NM_002081 2817 ENSG00000063660 GPC1 chr2 241233084Intergenic −141994 NM_002081 2817 ENSG00000063660 GPC1 chr2 241233090Intergenic −141988 NM_002081 2817 ENSG00000063660 GPC1 chr2 241233169Intergenic −141909 NM_002081 2817 ENSG00000063660 GPC1 chr2 241233214Intergenic −141864 NM_002081 2817 ENSG00000063660 GPC1 chr3 111431516intron (NM_001185106, intron 2 of 4) −19825 NM_001134437 90102ENSG00000144824 PHLDB2 chr3 111431559 intron (NM_001185106, intron 2 of4) −19782 NM_001134437 90102 ENSG00000144824 PHLDB2 chr4 3309964Intergenic −5908 NM_198229 6002 ENSG00000159788 RGS12 chr4 3310004 CpG−5868 NM_198229 6002 ENSG00000159788 RGS12 chr4 3311787 Intergenic −4085NM_198229 6002 ENSG00000159788 RGS12 chr4 3311917 Intergenic −3955NM_198229 6002 ENSG00000159788 RGS12 chr4 7228254 intron (NM_020777,intron 1 of 26) 33991 NM_020777 57537 ENSG00000184985 SORCS2 chr47228263 intron (NM_020777, intron 1 of 26) 34001 NM_020777 57537ENSG00000184985 SORCS2 chr4 7228304 intron (NM_020777, intron 1 of 26)34041 NM_020777 57537 ENSG00000184985 SORCS2 chr4 7228329 intron(NM_020777, intron 1 of 26) 34066 NM_020777 57537 ENSG00000184985 SORCS2chr4 7326173 intron (NM_020777, intron 1 of 26) 13999 NR_039961100616471 ENSG00000264658 MIR4798 chr4 7326188 intron (NM_020777, intron1 of 26) 14013 NR_039961 100616471 ENSG00000264658 MIR4798 chr4 7326270intron (NM_020777, intron 1 of 26) 14095 NR_039961 100616471ENSG00000264658 MIR4798 chr4 7326284 intron (NM_020777, intron 1 of 26)14109 NR_039961 100616471 ENSG00000264658 MIR4798 chr4 155758143HERVK22-int|LTR|ERVK 55488 NM_001277173 166863 ENSG00000151962 RBM46chr4 155763679 AluY|SINE|Alu 61024 NM_001277173 166863 ENSG00000151962RBM46 chr4 155763688 AluY|SINE|Alu 61033 NM_001277173 166863ENSG00000151962 RBM46 chr4 155763695 AluY|SINE|Alu 61040 NM_001277173166863 ENSG00000151962 RBM46 chr4 155812513 AluJb|SINE|Alu 109858NM_001277173 166863 ENSG00000151962 RBM46 chr4 155912924 Intergenic210269 NM_001277173 166863 ENSG00000151962 RBM46 chr4 155965520LTR12C|LTR|ERV1 −164266 NM_000910 4887 ENSG00000185149 NPY2R chr4155965532 LTR12C|LTR|ERV1 −164254 NM_000910 4887 ENSG00000185149 NPY2Rchr4 155965538 LTR12C|LTR|ERV1 −164248 NM_000910 4887 ENSG00000185149NPY2R chr4 155965544 LTR12C|LTR|ERV1 −164242 NM_000910 4887ENSG00000185149 NPY2R chr4 155965553 LTR12C|LTR|ERV1 −164233 NM_0009104887 ENSG00000185149 NPY2R chr4 155992200 AluSq|SINE|Alu −137586NM_000910 4887 ENSG00000185149 NPY2R chr4 156002533 Intergenic −127253NM_000910 4887 ENSG00000185149 NPY2R chr5 1003895 Intergenic −5020NM_033120 85409 ENSG00000145506 NKD2 chr5 1004045 CpG −4870 NM_03312085409 ENSG00000145506 NKD2 chr5 1004051 CpG −4864 NM_033120 85409ENSG00000145506 NKD2 chr5 1004064 CpG −4851 NM_033120 85409ENSG00000145506 NKD2 chr5 1004077 CpG −4838 NM_033120 85409ENSG00000145506 NKD2 chr5 1004089 CpG −4825 NM_033120 85409ENSG00000145506 NKD2 chr5 1004118 CpG −4797 NM_033120 85409ENSG00000145506 NKD2 chr5 1004128 CpG −4787 NM_033120 85409ENSG00000145506 NKD2 chr5 1004135 CpG −4779 NM_033120 85409ENSG00000145506 NKD2 chr5 1004148 CpG −4767 NM_033120 85409ENSG00000145506 NKD2 chr5 1004157 CpG −4758 NM_033120 85409ENSG00000145506 NKD2 chr5 1004184 CpG −4731 NM_033120 85409ENSG00000145506 NKD2 chr5 1004198 CpG −4717 NM_033120 85409ENSG00000145506 NKD2 chr5 1004234 CpG −4681 NM_033120 85409ENSG00000145506 NKD2 chr5 1004243 CpG −4668 NM_033120 85409ENSG00000145506 NKD2 chr5 1004259 CpG −4656 NM_033120 85409ENSG00000145506 NKD2 chr5 1004269 CpG −4646 NM_033120 85409ENSG00000145506 NKD2 chr5 1004288 CpG −4627 NM_033120 85409ENSG00000145506 NKD2 chr5 1004304 CpG −4611 NM_033120 85409ENSG00000145506 NKD2 chr5 1004351 CpG −4564 NM_033120 85409ENSG00000145506 NKD2 chr5 1004357 CpG −4557 NM_033120 85409ENSG00000145506 NKD2 chr5 1004365 CpG −4550 NM_033120 85409ENSG00000145506 NKD2 chr5 134827336 CpG −39302 NM_001099221 497189ENSG00000255833 TIFAB chr5 134827353 CpG −39314 NM_001099221 497189ENSG00000255833 TIFAB chr5 134827364 CpG −39325 NM_001099221 497189ENSG00000255833 TIFAB chr5 134827378 CpG −39339 NM_001099221 497189ENSG00000255833 TIFAB chr5 138441347 intron (NM_001037633, intron 4 of10) 92707 NM_001037633 64374 ENSG00000120725 SIL1 chr5 138441377 intron(NM_001037633, intron 4 of 10) 92677 NM_001037633 64374 ENSG00000120725SIL1 chr5 138441561 intron (NM_001037633, intron 4 of 10) 92494NM_001037633 64374 ENSG00000120725 SIL1 chr5 179401802 intron(NM_018434, intron 5 of 8) 40593 NR_029885 442908 ENSG00000198995 MIR340chr5 179401833 intron (NM_018434, intron 5 of 8) 40562 NR_029885 442908ENSG00000198995 MIR340 chr5 179401843 intron (NM_018434, intron 5 of 8)40552 NR_029885 442908 ENSG00000198995 MIR340 chr5 179401853 intron(NM_018434, intron 5 of 8) 40542 NR_029885 442908 ENSG00000198995 MIR340chr5 179401872 intron (NM_018434, intron 5 of 8) 40523 NR_029885 442908ENSG00000198995 MIR340 chr5 179588495 CpG 47714 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588504 CpG 47705 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588512 CpG 47697 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588528 CpG 47680 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588550 CpG 47659 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588590 CpG 47619 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588604 CpG 47604 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588617 CpG 47592 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588625 CpG 47584 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588631 CpG 47578 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588672 CpG 47537 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588687 CpG 47522 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588704 CpG 47504 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179588719 CpG 47490 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179597660 intron (NM_175062, intron 1 of13) 38549 NM_175062 255426 ENSG00000146090 RASGEF1C chr5 179597771intron (NM_175062, intron 1 of 13) 38438 NM_175062 255426ENSG00000146090 RASGEF1C chr5 179597812 intron (NM_175062, intron 1 of13) 38397 NM_175062 255426 ENSG00000146090 RASGEF1C chr6 64151793LTR12C|LTR|ERV1 −121907 NM_016571 51557 ENSG00000146166 LGSN chr6157549787 Intergenic 192228 NM_001363725 57492 ENSG00000049618 ARID1Bchr6 157549797 Intergenic 192238 NM_001363725 57492 ENSG00000049618ARID1B chr6 157549848 Intergenic 192289 NM_001363725 57492ENSG00000049618 ARID1B chr6 157550494 Intergenic 192935 NM_00136372557492 ENSG00000049618 ARID1B chr6 157550509 Intergenic 192950NM_001363725 57492 ENSG00000049618 ARID1B chr7 1447696 CpG 51408NM_182924 79778 ENSG00000164877 MICALL2 chr7 1447734 CpG 51370 NM_18292479778 ENSG00000164877 MICALL2 chr7 1447746 CpG 51358 NM_182924 79778ENSG00000164877 MICALL2 chr7 1447760 CpG 51344 NM_182924 79778ENSG00000164877 MICALL2 chr7 1447774 CpG 51329 NM_182924 79778ENSG00000164877 MICALL2 chr7 1447782 CpG 51322 NM_182924 79778ENSG00000164877 MICALL2 chr7 2006576 L1MEf|LINE|L1 −26371 NM_0013045258379 ENSG00000002822 MAD1L1 chr7 2006674 L1MEf|LINE|L1 −26469NM_001304525 8379 ENSG00000002822 MAD1L1 chr7 2007262 L1MC4a|LINE|L1−27057 NM_001304525 8379 ENSG00000002822 MAD1L1 chr7 2007279L1MC4a|LINE|L1 −27074 NM_001304525 8379 ENSG00000002822 MAD1L1 chr72007309 L1MC4a|LINE|L1 −27104 NM_001304525 8379 ENSG00000002822 MAD1L1chr7 2007394 intron (NM_001304523, intron 14 of 17) −27189 NM_0013045258379 ENSG00000002822 MAD1L1 chr7 2968280 exon (NM_032415, exon 13 of 25)−84340 NM_007353 2768 ENSG00000146535 GNA12 chr7 2968288 exon(NM_032415, exon 13 of 25) −84350 NM_007353 2768 ENSG00000146535 GNA12chr7 2968314 exon (NM_032415, exon 13 of 25) −84374 NM_007353 2768ENSG00000146535 GNA12 chr7 2968320 exon (NM_032415, exon 13 of 25)−84380 NM_007353 2768 ENSG00000146535 GNA12 chr7 2968352 CpG −84412NM_007353 2768 ENSG00000146535 GNA12 chr7 2968357 CpG −84417 NM_0073532768 ENSG00000146535 GNA12 chr7 2968405 CpG −84465 NM_007353 2768ENSG00000146535 GNA12 chr7 2968411 CpG −84471 NM_007353 2768ENSG00000146535 GNA12 chr7 2968426 CpG −84486 NM_007353 2768ENSG00000146535 GNA12 chr7 2968440 CpG −84502 NM_007353 2768ENSG00000146535 GNA12 chr7 2968454 CpG −84516 NM_007353 2768ENSG00000146535 GNA12 chr7 2968489 CpG −84553 NM_007353 2768ENSG00000146535 GNA12 chr7 2968504 CpG −84565 NM_007353 2768ENSG00000146535 GNA12 chr7 2968528 CpG −84588 NM_007353 2768ENSG00000146535 GNA12 chr7 2968552 CpG −84612 NM_007353 2768ENSG00000146535 GNA12 chr7 2968558 CpG −84618 NM_007353 2768ENSG00000146535 GNA12 chr7 2968565 CpG −84626 NM_007353 2768ENSG00000146535 GNA12 chr7 2968585 CpG −84645 NM_007353 2768ENSG00000146535 GNA12 chr7 2968593 CpG −84653 NM_007353 2768ENSG00000146535 GNA12 chr7 2968625 intron (NM_001324281, intron 13 of25) −84685 NM_007353 2768 ENSG00000146535 GNA12 chr7 2968684 intron(NM_001324281, intron 13 of 25) −84744 NM_007353 2768 ENSG00000146535GNA12 chr7 2968706 intron (NM_001324281, intron 13 of 25) −84766NM_007353 2768 ENSG00000146535 GNA12 chr7 26667584 Intergenic −9904NR_161202 285941 C7orf71 chr7 26667613 Intergenic −9875 NR_161202 285941C7orf71 chr7 26667674 Intergenic −9814 NR_161202 285941 C7orf71 chr726667709 Intergenic −9779 NR_161202 285941 C7orf71 chr7 35505816Intergenic 152352 NR_038864 401324 LOC401324 chr7 35505825 Intergenic152361 NR_038864 401324 LOC401324 chr7 41086116 Intergenic −55084NR_110832 101928773 ENSG00000224017 LINC01449 chr7 41086123 Intergenic−55077 NR_110832 101928773 ENSG00000224017 LINC01449 chr7 41086140Intergenic −55060 NR_110832 101928773 ENSG00000224017 LINC01449 chr7101622017 intron (NM_001202544, intron 2 of 21) 161113 NM_181552 1523ENSG00000257923 CUX1 chr7 101622057 intron (NM_001202544, intron 2 of21) 161153 NM_181552 1523 ENSG00000257923 CUX1 chr7 101622176L2a|LINE|L2 161275 NM_181552 1523 ENSG00000257923 CUX1 chr7 115992730Intergenic −65951 NR_130922 102724434 ENSG00000237870 LOC102724434 chr7115992814 L2|LINE|L2 −66035 NR_130922 102724434 ENSG00000237870LOC102724434 chr7 115998982 AluY|SINE|Alu −72203 NR_130922 102724434ENSG00000237870 LOC102724434 chr7 115999026 AluY|SINE|Alu −72247NR_130922 102724434 ENSG00000237870 LOC102724434 chr7 115999448AluSx1|SINE|Alu −72669 NR_130922 102724434 ENSG00000237870 LOC102724434chr7 115999464 AluSx1|SINE|Alu −72685 NR_130922 102724434ENSG00000237870 LOC102724434 chr7 116099337 HERVH-int|LTR|ERV1 −40453NM_001233 858 ENSG00000105971 CAV2 chr7 150668588 intron (NM_000238,intron 2 of 14) 6812 NM_172056 3757 ENSG00000055118 KCNH2 chr7 150669120intron (NM_000238, intron 2 of 14) 6280 NM_172056 3757 ENSG00000055118KCNH2 chr7 150811991 exon (NM_001308305, exon 1 of 9) 268 NM_001308305116988 ENSG00000133612 AGAP3 chr7 150812075 exon (NM_001308305, exon 1of 9) 352 NM_001308305 116988 ENSG00000133612 AGAP3 chr7 150812111 exon(NM_001308305, exon 1 of 9) 388 NM_001308305 116988 ENSG00000133612AGAP3 chr7 150812201 exon (NM_001308305, exon 1 of 9) 478 NM_001308305116988 ENSG00000133612 AGAP3 chr7 150812215 exon (NM_001308305, exon 1of 9) 493 NM_001308305 116988 ENSG00000133612 AGAP3 chr7 150812398 exon(NM_001308305, exon 1 of 9) 675 NM_001308305 116988 ENSG00000133612AGAP3 chr7 150812660 exon (NM_001308305, exon 1 of 9) 938 NM_001308305116988 ENSG00000133612 AGAP3 chr7 157423275 intron (NM_001308268, intron14 of 22) −56163 NR_029689 406945 ENSG00000207960 MIR153-2 chr7157623246 intron (NM_001308268, intron 12 of 22) −24028 NR_038966100506585 LOC100506585 chr8 46929775 GSATX|Satellite|centr 599488NR_146077 389652 ENSG00000248498 ASNSP1 chr8 46935836GSATX|Satellite|centr 593427 NR_146077 389652 ENSG00000248498 ASNSP1chr8 46938035 GSATX|Satellite|centr 591228 NR_146077 389652ENSG00000248498 ASNSP1 chr8 46938044 GSATX|Satellite|centr 591219NR_146077 389652 ENSG00000248498 ASNSP1 chr8 46938657GSATX|Satellite|centr 590606 NR_146077 389652 ENSG00000248498 ASNSP1chr8 46938693 GSATX|Satellite|centr 590570 NR_146077 380652ENSG00000248498 ASNSP1 chr8 46938702 GSATX|Satellite|centr 590561NR_146077 389652 ENSG00000248498 ASNSP1 chr8 46940361FordPrefect|DNA|hAT-Tip100 588902 NR_146077 389652 ENSG00000248498ASNSP1 chr8 46940406 FordPrefect|DNA|hAT-Tip100 588857 NR_146077 389652ENSG00000248498 ASNSP1 chr8 58062363 LTR1D|LTR|ERV1 −68470 NR_038235100507651 ENSG00000253301 LINC01606 chr8 58062426 LTR1D|LTR|ERV1 −68407NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58062463LTR1D|LTR|ERV1 −68370 NR_038235 100507651 ENSG00000253301 LINC01606 chr858096948 AluSx1|SINE|Alu −33885 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58115010 Intergenic −15823 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58115060 Intergenic −15773 NR_038235100507651 ENSG00000253301 LINC01606 chr8 58115154 MER50-int|LTR|ERV1−15679 NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58115225MER50-int|LTR|ERV1 −15608 NR_038235 100507651 ENSG00000253301 LINC01606chr8 58115343 MER50-int|LTR|ERV1 −15490 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58115362 MER50-int|LTR|ERV1 −15471NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58122819MER50|LTR|ERV1 −8014 NR_038235 100507651 ENSG00000253301 LINC01606 chr858122836 MER50|LTR|ERV1 −7997 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58122848 MER50|LTR|ERV1 −7985 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58122861 MER50|LTR|ERV1 −7972 NR_038235100507651 ENSG00000253301 LINC01606 chr8 58123008 Intergenic −7825NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58126620MER50-int|LTR|ERV1 −4213 NR_038235 100507651 ENSG00000253301 LINC01606chr8 58126666 MER50-int|LTR|ERV1 −4167 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58126874 MER50-int|LTR|ERV1 −3959NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58127096MER50|LTR|ERV1 −3737 NR_038235 100507651 ENSG00000253301 LINC01606 chr858127515 MER50|LTR|ERV1 −3318 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58127556 MER50|LTR|ERV1 −3277 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58127613 MER50|LTR|ERV1 −3220 NR_038235100507651 ENSG00000253301 LINC01606 chr8 58130004 promoter-TSS(NR_038235) −829 NR_038235 100507651 ENSG00000253301 LINC01606 chr858130021 promoter-TSS (NR_038235) −812 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58130039 promoter-TSS (NR_038235) −794NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58131654 non-coding(NR_038235, exon 3 of 10) 821 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58131665 non-coding (NR_038235, exon 3 of 10) 832NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58131710MER50-int|LTR|ERV1 877 NR_038235 100507651 ENSG00000253301 LINC01606chr8 58131715 MER50-int|LTR|ERV1 882 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58131843 MER50-int|LTR|ERV1 1010 NR_038235 100507651ENSG00000253301 LINC01606 chr8 58131870 MER50-int|LTR|ERV1 1037NR_038235 100507651 ENSG00000253301 LINC01606 chr8 58133184 intron(NR_038235, intron 5 of 9) 2351 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58133215 intron (NR_038235, intron 5 of 9) 2382 NR_038235100507651 ENSG00000253301 LINC01606 chr8 58133315 intron (NR_038235,intron 5 of 9) 2482 NR_038235 100507651 ENSG00000253301 LINC01606 chr858133743 MER50|LTR|ERV1 2910 NR_038235 100507651 ENSG00000253301LINC01606 chr8 58171196 Intergenic −2587 NR_038874 286177ENSG00000253614 LOC286177 chr8 58171236 Intergenic −2545 NR_038874286177 ENSG00000253614 LOC286177 chr8 58192020 promoter-TSS (NR_026772)−80 NR_026772 26138 ENSG00000215117 LINC00588 chr8 61777862 exon(NM_001316690, exon 5 of 5) 102443 NR_034003 100130298 LOC100130298 chr861821531 Intergenic 58774 NR_034003 100130298 LOC100130298 chr8 61821546Intergenic 58759 NR_034003 100130298 LOC100130298 chr8 61821578C-rich|Low_complexity|Low_complexity 58727 NR_034003 100130298LOC100130298 chr8 73471538 AluSx|SINE|Alu 22080 NM_004770 9312ENSG00000182674 KCNB2 chr8 73480053 exon (NM_004770, exon 2 of 3) 30595NM_004770 9312 ENSG00000182674 KCNB2 chr8 73551842 intron (NM_004770,intron 2 of 2) −92436 NR_110656 101926908 ENSG00000253726 LOC101926908chr8 73849013 exon (NM_004770, exon 3 of 3) −72084 NM_017489 7013ENSG00000147601 TERF1 chr8 73849032 exon (NM_004770, exon 3 of 3) −72065NM_017489 7013 ENSG00000147601 TERF1 chr8 73849038 exon (NM_004770, exon3 of 3) −72059 NM_017489 7013 ENSG00000147601 TERF1 chr8 73849051 exon(NM_004770, exon 3 of 3) −72046 NM_017489 7013 ENSG00000147601 TERF1chr8 73849060 exon (NM_004770, exon 3 of 3) −72037 NM_017489 7013ENSG00000147601 TERF1 chr8 104117894 Intergenic −15364 NR_145429 379034LINC01181 chr8 140929837 intron (NM_001160372, intron 19 of 22) 180795NR_144431 359809 ENSG00000282164 PEG13 chr8 140930939 intron(NM_001160372, intron 19 of 22) 179693 NR_144431 359809 ENSG00000282164PEG13 chr8 140931316 intron (NM_001160372, intron 19 of 22) 179316NR_144431 359809 ENSG00000282164 PEG13 chr8 142367903 exon (NM_005293,exon 2 of 2) 9481 NM_005293 2843 ENSG00000204882 GPR20 chr8 142367951exon (NM_005293, exon 2 of 2) 9433 NM_005293 2843 ENSG00000204882 GPR20chr8 142367989 exon (NM_005293, exon 2 of 2) 9395 NM_005293 2843ENSG00000204882 GPR20 chr9 117049844 intron (NM_032888, intron 41 of 60)−35457 NM_000607 5004 ENSG00000229314 ORM1 chr9 117049850 intron(NM_032888, intron 41 of 60) −35451 NM_000607 5004 ENSG00000229314 ORM1chr9 117049862 intron (NM_032888, intron 41 of 60) −35439 NM_000607 5004ENSG00000229314 ORM1 chr9 117049885 intron (NM_032888, intron 41 of 60)−35416 NM_000607 5004 ENSG00000229314 ORM1 chr9 127105722 intron(NM_014397, intron 8 of 9) −10028 NR_027406 100129034 LOC100129034 chr9127105763 intron (NM_014397, intron 8 of 9) −9987 NR_027406 100129034LOC100129034 chr9 129895923 intron (NM_014636, intron 8 of 18) −11011NM_012098 23452 ENSG00000136859 ANGPTL2 chr9 136007375 promoter-TSS(NM_001271774) −833 NM_001271774 5900 ENSG00000160271 RALGDS chr9136007484 promoter-TSS (NM_001271774) −942 NM_001271774 5900ENSG00000160271 RALGDS chr9 136007594 intron (NM_001042368, intron 1 of17) −1052 NM_001271774 5900 ENSG00000160271 RALGDS chr9 136007599 intron(NM_001042368, intron 1 of 17) −1057 NM_001271774 5900 ENSG00000160271RALGDS chr9 136007615 intron (NM_001042368, intron 1 of 17) −1073NM_001271774 5900 ENSG00000160271 RALGDS chr9 136007712 intron(NM_001042368, intron 1 of 17) −1170 NM_001271774 5900 ENSG00000160271RALGDS chr9 136324027 MIR|SINE|MIR −1058 NM_001242369 11094ENSG00000160325 CACFD1 chr9 136324037 MIR|SINE|MIR −1048 NM_00124236911094 ENSG00000160325 CACFD1 chr9 136324064 intron (NM_139026, intron 28of 28) −1021 NM_001242369 11094 ENSG00000160325 CACFD1 chr9 138688868Intergenic 94839 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138688876Intergenic 94847 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138688902Intergenic 94873 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138688936Intergenic 94907 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138689094Intergenic 95066 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138689107Intergenic 95078 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138689483Intergenic 95454 NM_020822 57582 ENSG00000107147 KCNT1 chr9 138719312exon (NM_015447, exon 8 of 17) 80078 NM_015447 157922 ENSG00000130559CAMSAP1 chr9 138719386 exon (NM_015447, exon 8 of 17) 80004 NM_015447157922 ENSG00000130559 CAMSAP1 chr9 139419669 intron (NM_017617, intron2 of 33) −5593 NR_039820 100616242 ENSG00000263403 MIR4673 chr9139419769 intron (NM_017617, intron 2 of 33) −5693 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139419814 intron (NM_017617, intron 2 of33) −5738 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139419865intron (NM_017617, intron 2 of 33) −5792 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139419924 intron (NM_017617, intron 2 of33) −5848 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139419933intron (NM_017617, intron 2 of 33) −5859 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139419956 intron (NM_017617, intron 2 of33) −5880 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139420550intron (NM_017617, intron 2 of 33) −6474 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139420561 intron (NM_017617, intron 2 of33) −6485 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139420578intron (NM_017617, intron 2 of 33) −6502 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139420602 intron (NM_017617, intron 2 of33) −6526 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139420641intron (NM_017617, intron 2 of 33) −6565 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139420862 intron (NM_017617, intron 2 of33) −6786 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139420914intron (NM_017617, intron 2 of 33) −6838 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421144 CpG −7069 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421220 CpG −7144 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421241 CpG −7165 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421257 CpG −7182 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421267 CpG −7191 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421321 CpG −7245 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421342 CpG −7266 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139421362 CpG −7286 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139422178 intron (NM_017617, intron 2 of33) −8102 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139422203intron (NM_017617, intron 2 of 33) −8127 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139422218 intron (NM_017617, intron 2 of33) −8143 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139422266intron (NM_017617, intron 2 of 33) −8192 NR_039820 100616242ENSG00000263403 MIR4673 chr9 139422290 intron (NM_017617, intron 2 of33) −8214 NR_039820 100616242 ENSG00000263403 MIR4673 chr9 139422314intron (NM_017617, intron 2 of 33) −8238 NR_039820 100616242ENSG00000263403 MIR4673 chr10 23976532 AluY|SINE|Alu −7122 NM_00109850056243 ENSG00000120549 KIAA1217 chr10 23976581 AluY|SINE|Alu −7073NM_001098500 56243 ENSG00000120549 KIAA1217 chr10 72489844 intron(NM_139155, intron 5 of 21) 52483 NR_134532 219793 ENSG00000166220 TBATAchr10 72489870 exon (NM_080722, exon 6 of 22) 52454 NR_134532 219793ENSG00000166220 TBATA chr10 72489889 exon (NM_080722, exon 6 of 22)52438 NR_134532 219793 ENSG00000166220 TBATA chr10 72489949 exon(NM_080722, exon 6 of 22) 52378 NR_134532 219793 ENSG00000166220 TBATAchr10 72489967 exon (NM_080722, exon 6 of 22) 52360 NR_134532 219793ENSG00000166220 TBATA chr10 72489983 exon (NM_080722, exon 6 of 22)52344 NR_134532 219793 ENSG00000166220 TBATA chr10 119590052 Intergenic−216278 NR_026939 255082 ENSG00000177640 CASC2 chr10 134562610 CpG 37039NM_177400 84504 ENSG00000148826 NKX6-2 chr10 134563052 exon(NM_001321042, exon 7 of 13) 36597 NM_177400 84504 ENSG00000148826NKX6-2 chr10 134563060 exon (NM_001321042, exon 7 of 13) 36589 NM_17740084504 ENSG00000148826 NKX6-2 chr10 134563098 exon (NM_001321042, exon 7of 13) 36551 NM_177400 84504 ENSG00000148826 NKX6-2 chr10 134563109 exon(NM_001321042, exon 7 of 13) 36540 NM_177400 84504 ENSG00000148826NKX6-2 chr10 134563144 CpG-3491 36505 NM_177400 84504 ENSG00000148826NKX6-2 chr10 134563149 CpG-3491 36500 NM_177400 84504 ENSG00000148826NKX6-2 chr10 134563186 CpG-3491 36463 NM_177400 84504 ENSG00000148826NKX6-2 chr10 134563199 CpG-3491 36450 NM_177400 84504 ENSG00000148826NKX6-2 chr11 2495501 intron (NM_181798, intron 1 of 15) 12819 NM_1817983784 ENSG00000053918 KCNQ1 chr11 2495543 intron (NM_181798, intron 1 of15) 12861 NM_181798 3784 ENSG00000053918 KCNQ1 chr11 2495585 intron(NM_181798, intron 1 of 15) 12903 NM_181798 3784 ENSG00000053918 KCNQ1chr11 2495609 intron (NM_181798, intron 1 of 15) 12927 NM_181798 3784ENSG00000053918 KCNQ1 chr11 68967954 Intergenic −28926 NR_104161 338694ENSG00000261070 LOC338694 chr11 68967994 Intergenic −28966 NR_104161338694 ENSG00000261070 LOC338694 chr11 68968016 Intergenic −28988NR_104161 338694 ENSG00000261070 LOC338694 chr11 68968032 Intergenic−29004 NR_104161 338694 ENSG00000261070 LOC338694 chr11 68968042Intergenic −29014 NR_104161 338694 ENSG00000261070 LOC338694 chr1168968141 Intergenic −29115 NR_104161 338694 ENSG00000261070 LOC338694chr11 68968151 Intergenic −29123 NR_104161 338694 ENSG00000261070LOC338694 chr11 68968156 Intergenic −29128 NR_104161 338694ENSG00000261070 LOC338694 chr11 68968182 Intergenic −29154 NR_104161338694 ENSG00000261070 LOC338694 chr11 68968214 Intergenic −29186NR_104161 338694 ENSG00000261070 LOC338694 chr11 68968240 Intergenic−29212 NR_104161 338694 ENSG00000261070 LOC338694 chr11 68968267Intergenic −29240 NR_104161 338694 ENSG00000261070 LOC338694 chr1170851529 intron (NM_012309, intron 2 of 22) 84311 NM_012309 22941ENSG00000162105 SHANK2 chr11 70851574 intron (NM_012309, intron 2 of 22)84266 NM_012309 22941 ENSG00000162105 SHANK2 chr11 70851603 intron(NM_012309, intron 2 of 22) 84237 NM_012309 22941 ENSG00000162105 SHANK2chr11 70851619 intron (NM_012309, intron 2 of 22) 84221 NM_012309 22941ENSG00000162105 SHANK2 chr11 70851638 intron (NM_012309, intron 2 of 22)84202 NM_012309 22941 ENSG00000162105 SHANK2 chr11 70851713 intron(NM_012309, intron 2 of 22) 84127 NM_012309 22941 ENSG00000162105 SHANK2chr11 70851722 intron (NM_012309, intron 2 of 22) 84118 NM_012309 22941ENSG00000162105 SHANK2 chr11 70851730 intron (NM_012309, intron 2 of 22)84110 NM_012309 22941 ENSG00000162105 SHANK2 chr11 70851827 intron(NM_012309, intron 2 of 22) 84013 NM_012309 22941 ENSG00000162105 SHANK2chr11 70851836 intron (NM_012309, intron 2 of 22) 84004 NM_012309 22941ENSG00000162105 SHANK2 chr11 70851859 intron (NM_012309, intron 2 of 22)83981 NM_012309 22941 ENSG00000162105 SHANK2 chr11 70851868 intron(NM_012309, intron 2 of 22) 83972 NM_012309 22941 ENSG00000162105 SHANK2chr11 70851883 intron (NM_012309, intron 2 of 22) 83957 NM_012309 22941ENSG00000162105 SHANK2 chr11 70851889 intron (NM_012309, intron 2 of 22)83951 NM_012309 22941 ENSG00000162105 SHANK2 chr11 70851914 intron(NM_012309, intron 2 of 22) 83926 NM_012309 22941 ENSG00000162105 SHANK2chr11 70862301 intron (NM_012309, intron 1 of 22) 73539 NM_012309 22941ENSG00000162105 SHANK2 chr11 70862379 intron (NM_012309, intron 1 of 22)73461 NM_012309 22941 ENSG00000162105 SHANK2 chr11 70862397 intron(NM_012309, intron 1 of 22) 73443 NM_012309 22941 ENSG00000162105 SHANK2chr11 70862405 intron (NM_012309, intron 1 of 22) 73435 NM_012309 22941ENSG00000162105 SHANK2 chr11 111265961 Intergenic −15963 NM_006235 5450ENSG00000110777 POU2AE1 chr11 111266000 Intergenic −16002 NM_006235 5450ENSG00000110777 POU2AE1 chr11 111266014 Intergenic −16016 NM_006235 5450ENSG00000110777 POU2AE1 chr11 111266031 Intergenic −16033 NM_006235 5450ENSG00000110777 POU2AE1 chr11 111266119 Intergenic −16121 NM_006235 5450ENSG00000110777 POU2AF1 chr11 115829517 Intergenic −198601 NR_034148283143 LINC00900 chr11 115829550 Intergenic −198634 NR_034148 283143LINC00900 chr11 115830020 Intergenic −199104 NR_034148 283143 LINC00900chr11 115830200 MIR3|SINE|MIR −199284 NR_034148 283143 LINC00900 chr11133902554 non-coding (NR_027276, exon 1 of 3) 389 NR_027276 100128239ENSG00000204241 LINC02731 chr11 133902596 non-coding (NR_027276, exon 1of 3) 431 NR_027276 100128239 ENSG00000204241 LINC02731 chr11 133902615non-coding (NR_027276, exon 1 of 3) 450 NR_027276 100128239ENSG00000204241 LINC02731 chr11 133902626 non-coding (NR_027276, exon 1of 3) 461 NR_027276 100128239 ENSG00000204241 LINC02731 chr11 133902656non-coding (NR_027276, exon 1 of 3) 491 NR_027276 100128239ENSG00000204241 LINC02731 chr11 133902669 non-coding (NR_027276, exon 1of 3) 504 NR_027276 100128239 ENSG00000204241 LINC02731 chr11 133902689non-coding (NR_027276, exon 1 of 3) 524 NR_027276 100128239ENSG00000204241 LINC02731 chr11 133902724 non-coding (NR_027276, exon 1of 3) 561 NR_027276 100128239 ENSG00000204241 LINC02731 chr11 133902737non-coding (NR_027276, exon 1 of 3) 572 NR_027276 100128239ENSG00000204241 LINC02731 chr11 133902744 non-coding (NR_027276, exon 1of 3) 579 NR_027276 100128239 ENSG00000204241 LINC02731 chr11 133902766intron (NR_027276, intron 1 of 2) 601 NR_027276 100128239ENSG00000204241 LINC02731 chr12 1957456 L1MC5|LINE|L1 27727 NM_001039029654429 ENSG00000166159 LRTM2 chr12 1957466 L1MC5|LINE|L1 27737NM_001039029 654429 ENSG00000166159 LRTM2 chr12 1957486 L1MC5|LINE|L127757 NM_001039029 654429 ENSG00000166159 LRTM2 chr12 1957501L1MC5|LINE|L1 27772 NM_001039029 654429 ENSG00000166159 LRTM2 chr121957566 L1MC5|LINE|L1 27837 NM_001039029 654429 ENSG00000166159 LRTM2chr12 34488345 GSATII|Satellite|centr 312916 NM_032834 84920ENSG00000139133 ALG10 chr12 34488352 GSATII|Satellite|centr 312923NM_032834 84920 ENSG00000139133 ALG10 chr12 66111480 AluY|SINE|Alu−75330 NR_120432 100507065 LOC100507065 chr12 66111548 LTR8A|LTR|ERV1−75398 NR_120432 100507065 LOC100507065 chr12 66114657 Intergenic −78507NR_120432 100507065 LOC100507065 chr12 66114687 Intergenic −78537NR_120432 100507065 LOC100507065 chr12 66114695 Intergenic −78545NR_120432 100507065 LOC100507065 chr12 66262212 intron (NR_158984,intron 1 of 2) 13144 NR_120478 100129940 ENSG00000197301 HMGA2-AS1 chr1266262228 intron (NR_158984, intron 1 of 2) 13126 NR_120478 100129940ENSG00000197301 HMGA2-AS1 chr12 115109512 3′ UTR (NM_005996, exon 7 of7) 12466 NM_005996 6926 ENSG00000135111 TBX3 chr12 115109529 3′ UTR(NM_005996, exon 7 of 7) 12449 NM_005996 6926 ENSG00000135111 TBX3 chr12115109718 exon (NM_005996, exon 7 of 7) 12260 NM_005996 6926ENSG00000135111 TBX3 chr12 115109960 exon (NM_005996, exon 7 o7) 12018NM_005996 6926 ENSG00000135111 TBX3 chr12 115112024 exon (NM_005996,exon 6 of 7) 9954 NM_005996 6926 ENSG00000135111 TBX3 chr12 115112037exon (NM_005996, exon 6 of 7) 9941 NM_005996 6926 ENSG00000135111 TBX3chr12 124947867 intron (NM_001206654, intron 7 of 47) 104289NM_001206654 9612 ENSG00000196498 NCOR2 chr12 124948139 intron(NM_001206654, intron 7 of 47) 104017 NM_001206654 9612 ENSG00000196498NCOR2 chr13 114523664 3′ UTR (NM_000820, exon 15 of 15) 5083 NR_044995650669 GAS6-AS1 chr13 114523669 3′ UTR (NM_000820, exon 15 of 15) 5088NR_044995 650669 GAS6-AS1 chr13 114523717 3′ UTR (NM_000820, exon 15 of15) 5136 NR_044995 650669 GAS6-AS1 chr13 114523760 3′ UTR (NM_000820,exon 15 of 15) 5179 NR_044995 650669 GAS6-AS1 chr13 114523787 3′ UTR(NM_000820, exon 15 of 15) 5206 NR_044995 650669 GAS6-AS1 chr13114523796 3′ UTR (NM_000820, exon 15 of 15) 5215 NR_044995 650669GAS6-AS1 chr13 114523819 3′ UTR (NM_000820, exon 15 of 15) 5239NR_044995 650669 GAS6-AS1 chr13 114523826 3′ UTR (NM_000820, exon 15 of15) 5245 NR_044995 650669 GAS6-AS1 chr13 114523875 exon (NM_000820, exon15 of 15) 5294 NR_044995 650669 GAS6-AS1 chr13 114523883 exon(NM_000820, exon 15 of 15) 5302 NR_044995 650669 GAS6-AS1 chr13114523896 exon (NM_000820, exon 15 of 15) 5316 NR_044995 650669 GAS6-AS1chr13 114523904 exon (NM_000820, exon 15 of 15) 5323 NR_044995 650669GAS6-AS1 chr13 114523923 exon (NM_000820, exon 15 of 15) 5342 NR_044995650669 GAS6-AS1 chr13 114523948 exon (NM_000820, exon 15 of 15) 5368NR_044995 650669 GAS6-AS1 chr13 114523958 exon (NM_000820, exon 15 of15) 5378 NR_044995 650669 GAS6-AS1 chr13 114523970 exon (NM_000820, exon15 of 15) 5389 NR_044995 650669 GAS6-AS1 chr13 114523982 exon(NM_000820, exon 15 of 15) 5401 NR_044995 650669 GAS6-AS1 chr13114523996 CpG 5415 NR_044995 650669 GAS6-AS1 chr13 114524029 CpG 5448NR_044995 650669 GAS6-AS1 chr13 114524093 CpG 5512 NR_044995 650669GAS6-AS1 chr13 114524130 CpG 5549 NR_044995 650669 GAS6-AS1 chr13114524137 CpG 5558 NR_044995 650669 GAS6-AS1 chr13 114524149 CpG 5568NR_044995 650669 GAS6-AS1 chr13 114524157 CpG 5576 NR_044995 650669GAS6-AS1 chr13 114524420 intron (NM_000820, intron 14 of 14) 5839NR_044995 650669 GAS6-AS1 chr13 114524429 intron (NM_000820, intron 14of 14) 5848 NR_044995 650669 GAS6-AS1 chr13 114524439 intron (NM_000820,intron 14 of 14) 5858 NR_044995 650669 GAS6-AS1 chr13 114524473 intron(NM_000820, intron 14 of 14) 5892 NR_044995 650669 GAS6-AS1 chr13114524509 intron (NM_000820, intron 14 of 14) 5928 NR_044995 650669GAS6-AS1 chr13 114524517 intron (NM_000820, intron 14 of 14) 5936NR_044995 650669 GAS6-AS1 chr13 114524583 intron (NM_000820, intron 14of 14) 6003 NR_044995 650669 GAS6-AS1 chr14 20684518 Intergenic −7349NM_001004480 122748 ENSG00000176219 OR11H6 chr14 20684528 Intergenic−7339 NM_001004480 122748 ENSG00000176219 OR11H6 chr14 76957115 intron(NM_004452, intron 7 of 10) 119427 NM_004452 2103 ENSG00000119715 ESRRBchr14 76957138 intron (NM_004452, intron 7 of 10) 119450 NM_004452 2103ENSG00000119715 ESRRB chr14 76957152 intron (NM_004452, intron 7 of 10)119464 NM_004452 2103 ENSG00000119715 ESRRB chr14 76957199 intron(NM_004452, intron 7 of 10) 119511 NM_004452 2103 ENSG00000119715 ESRRBchr14 93423461 intron (NM_001142593, intron 8 of 10) 33968 NM_0012751113 ENSG00000100604 CHGA chr14 93423503 intron (NM_001142593, intron 8of 10) 34010 NM_001275 1113 ENSG00000100604 CHGA chr14 93423558 intron(NM_001142593, intron 8 of 10) 34065 NM_001275 1113 ENSG00000100604 CHGAchr14 93425210 MIRb|SINE|MIR 35717 NM_001275 1113 ENSG00000100604 CHGAchr14 93425284 MIRb|SINE|MIR 35791 NM_001275 1113 ENSG00000100604 CHGAchr14 93425331 MIRb|SINE|MIR 35838 NM_001275 1113 ENSG00000100604 CHGAchr14 93425520 intron (NM_001142593, intron 7 of 10) 36027 NM_0012751113 ENSG00000100604 CHGA chr14 93425529 intron (NM_001142593, intron 7of 10) 36036 NM_001275 1113 ENSG00000100604 CHGA chr14 93425655 intron(NM_001142593, intron 7 of 10) 36162 NM_001275 1113 ENSG00000100604 CHGAchr14 93425687 intron (NM_001142593, intron 7 of 10) 36194 NM_0012751113 ENSG00000100604 CHGA chr14 93425735 intron (NM_001142593, intron 7of 10) 36242 NM_001275 1113 ENSG00000100604 CHGA chr14 93425741 intron(NM_001142593, intron 7 of 10) 36249 NM_001275 1113 ENSG00000100604 CHGAchr14 93426221 intron (NM_001142593, intron 7 of 10) 36728 NM_0012751113 ENSG00000100604 CHGA chr14 93426229 intron (NM_001142593, intron 7of 10) 36737 NM_001275 1113 ENSG00000100604 CHGA chr14 93426247 intron(NM_001142593, intron 7 of 10) 36754 NM_001275 1113 ENSG00000100604 CHGAchr14 93426257 intron (NM_001142593, intron 7 of 10) 36764 NM_0012751113 ENSG00000100604 CHGA chr14 93426336 intron (NM_001142593, intron 7of 10) 36843 NM_001275 1113 ENSG00000100604 CHGA chr14 93426381 intron(NM_001142593, intron 7 of 10) 36888 NM_001275 1113 ENSG00000100604 CHGAchr14 93426456 intron (NM_001142593, intron 7 of 10) 36963 NM_0012751113 ENSG00000100604 CHGA chr14 93426481 intron (NM_001142593, intron 7of 10) 36988 NM_001275 1113 ENSG00000100604 CHGA chr14 93426499 intron(NM_001142593, intron 7 of 10) 37006 NM_001275 1113 ENSG00000100604 CHGAchr14 93426875 MIRb|SINE|MIR 37382 NM_001275 1113 ENSG00000100604 CHGAchr14 93426916 MIRb|SINE|MIR 37423 NM_001275 1113 ENSG00000100604 CHGAchr14 101158277 Intergenic 34674 NR_024096 283601 ENSG00000196273LINC00523 chr14 101158294 Intergenic 34691 NR_024096 283601ENSG00000196273 LINC00523 chr14 101159404 L2a|LINE|L2 −33796 NM_0038368788 ENSG00000185559 DLK1 chr14 101159430 L2a|LINE|L2 −33769 NM_0038368788 ENSG00000185559 DLKl chr14 101159551 L2a|LINE|L2 −33647 NM_0038368788 ENSG00000185559 DLK1 chr14 101250153 Intergenic −30673 NR_039729100616495 ENSG00000266461 MIR2392 chr14 101250165 Intergenic −30661NR_039729 100616495 ENSG00000266461 MIR2392 chr14 101250240Charlie13b|DNA|hAT-Charlie −30584 NR_039729 100616495 ENSG00000266461MIR2392 chr14 101250254 Charlie13b|DNA|hAT-Charlie −30571 NR_039729100616495 ENSG00000266461 MIR2392 chr14 101250279Charlie13b|DNA|hAT-Charlie −30547 NR_039729 100616495 ENSG00000266461MIR2392 chr14 101640895 Intergenic 53705 NR_146490 101929422ENSG00000259004 LINC02285 chr14 101640910 Intergenic 53719 NR_146490101929422 ENSG00000259004 LINC02285 chr14 101640942 Intergenic 53751NR_146490 101929422 ENSG00000259004 LINC02285 chr14 101640959 Intergenic53768 NR_146490 101929422 ENSG00000259004 LINC02285 chr14 105347685intron (NM_001112726, intron 6 of 18) 16036 NR_162135 113219454 MIR12121chr14 105347700 intron (NM_001112726, intron 6 of 18) 16051 NR_162135113219454 MIR12121 chr14 105347712 intron (NM_001112726, intron 6 of 18)16063 NR_162135 113219454 MIR12121 chr14 105347802 intron (NM_001112726,intron 6 of 18) 16153 NR_162135 113219454 MIR12121 chr14 105347810intron (NM_001112726, intron 6 of 18) 16161 NR_162135 113219454 MIR12121chr14 105347834 intron (NM_001112726, intron 6 of 18) 16185 NR_162135113219454 MIR12121 chr14 105347851 intron (NM_001112726, intron 6 of 18)16202 NR_162135 113219454 MIR12121 chr14 105347961 intron (NM_001112726,intron 6 of 18) 16312 NR_162135 113219454 MIR12121 chr15 22559959 intron(NR_033735, intron 1 of 2) 13396 NR_033735 646396 REREP3 chr15 22559966intron (NR_033735, intron 1 of 2) 13403 NR_033735 646396 REREP3 chr1522567152 non-coding (NR_033735, exon 2 of 3) 20589 NR_033735 646396REREP3 chr15 22567172 non-coding (NR_033735, exon 2 of 3) 20609NR_033735 646396 REREP3 chr15 22571751 TTS (NR_033735) 25188 NR_033735646396 REREP3 chr15 22571783 TTS (NR_033735) 25220 NR_033735 646396REREP3 chr15 22581845 AluSc8|SINE|Alu 35282 NR_033735 646396 REREP3chr15 22581981 AluSc8|SINE|Alu 35418 NR_033735 646396 REREP3 chr1574521143 Intergenic −7522 NM_025055 80125 ENSG00000140481 CCDC33 chr1574521156 Intergenic −7509 NM_025055 80125 ENSG00000140481 CCDC33 chr1574521297 Intergenic −7368 NM_025055 80125 ENSG00000140481 CCDC33 chr1574521344 Intergenic −7321 NM_025055 80125 ENSG00000140481 CCDC33 chr1574521357 Intergenic −7308 NM_025055 80125 ENSG00000140481 CCDC33 chr1574521364 Intergenic −7301 NM_025055 80125 ENSG00000140481 CCDC33 chr1594613752 AmnSINE1|SINE|Deu 37412 NR_120320 101927112 ENSG00000259724LINC01581 chr15 94613766 AmnSINE1|SINE|Deu 37399 NR_120320 101927112ENSG00000259724 LINC01581 chr15 94613787 AmnSINE1|SINE|Deu 37378NR_120320 101927112 ENSG00000259724 LINC01581 chr15 94613823AmnSINE1|SINE|Deu 37341 NR_120320 101927112 ENSG00000259724 LINC01581chr15 94613901 intron (NR_120320, intron 2 of 8) 37264 NR_120320101927112 ENSG00000259724 LINC01581 chr17 915606 MER102a|DNA|hAT-Charlie10191 NR_036148 100422835 ENSG00000264429 MIR3183 chr17 915643MER102a|DNA|hAT-Charlie 10154 NR_036148 100422835 ENSG00000264429MIR3183 chr17 915806 CpG 9989 NR_036148 100422835 ENSG00000264429MIR3183 chr17 915890 CpG 9907 NR_036148 100422835 ENSG00000264429MIR3183 chr17 915912 CpG 9885 NR_036148 100422835 ENSG00000264429MIR3183 chr17 7010397 exon (NM_001201352, exon 7 of 9) 7230 NM_080914433 ENSG00000161944 ASGR2 chr17 7010445 exon (NM_001201352, exon 7 of 9)7182 NM_080914 433 ENSG00000161944 ASGR2 chr17 7010504 intron(NM_001181, intron 6 of 8) 7123 NM_080914 433 ENSG00000161944 ASGR2chr17 7010533 intron (NM_001181, intron 6 of 8) 7094 NM_080914 433ENSG00000161944 ASGR2 chr17 7010548 exon (NM_001201352, exon 6 of 9)7079 NM_080914 433 ENSG00000161944 ASGR2 chr17 7010630 exon(NM_001201352, exon 6 of 9) 6997 NM_080914 433 ENSG00000161944 ASGR2chr17 7010663 intron (NM_001181, intron 5 of 8) 6964 NM_080914 433ENSG00000161944 ASGR2 chr17 10728383 3′ UTR (NM_001101387, exon 2 of 2)13019 NM_001101387 644139 ENSG00000233670 PIRT chr17 10740512 intron(NM_001101387, intron 1 of 1) 890 NM_001101387 644139 ENSG00000233670PIRT chr17 10740558 intron (NM_001101387, intron 1 of 1) 842NM_001101387 644139 ENSG00000233670 PIRT chr17 10740569 intron(NM_001101387, intron 1 of 1) 833 NM_001101387 644139 ENSG00000233670PIRT chr17 10740581 intron (NM_001101387, intron 1 of 1) 821NM_001101387 644139 ENSG00000233670 PIRT chr17 10740595 intron(NM_001101387, intron 1 of 1) 807 NM_001101387 644139 ENSG00000233670PIRT chr17 17677711 intron (NM_030665, intron 2 of 5) 5130 NR_024007140771 ENSG00000226746 SMCR5 chr17 17677757 intron (NM_030665, intron 2of 5) 5084 NR_024007 140771 ENSG00000226746 SMCR5 chr17 17677887 intron(NM_030665, intron 2 of 5) 4954 NR_024007 140771 ENSG00000226746 SMCR5chr17 21286388 intron (NM_021012, intron 1 of 2) 6721 NM_021012 3768ENSG00000184185 KCNJ12 chr17 21286444 intron (NM_021012, intron 1 of 2)6777 NM_021012 3768 ENSG00000184185 KCNJ12 chr17 21286486 intron(NM_021012, intron 1 of 2) 6819 NM_021012 3768 ENSG00000184185 KCNJ12chr17 21286510 intron (NM_021012, intron 1 of 2) 6846 NM_021012 3768ENSG00000184185 KCNJ12 chr17 21286534 intron (NM_021012, intron 1 of 2)6867 NM_021012 3768 ENSG00000184185 KCNJ12 chr17 21286708 intron(NM_021012, intron 1 of 2) 7042 NM_021012 3768 ENSG00000184185 KCNJ12chr17 21286741 intron (NM_021012, intron 1 of 2) 7074 NM_021012 3768ENSG00000184185 KCNJ12 chr17 21286747 intron (NM_021012, intron 1 of 2)7080 NM_021012 3768 ENSG00000184185 KCNJ12 chr17 28299552 intron(NR_026738, intron 4 of 15) 30902 NM_198529 374786 ENSG00000176927EFCAB5 chr17 28299565 intron (NR_026738, intron 4 of 15) 30915 NM_198529374786 ENSG00000176927 EFCAB5 chr17 28299571 intron (NR_026738, intron 4of 15) 30922 NM_198529 374786 ENSG00000176927 EFCAB5 chr17 28299598intron (NR_026738, intron 4 of 15) 30948 NM_198529 374786ENSG00000176927 EFCAB5 chr17 28299697 intron (NR_026738, intron 4 of 15)31047 NM_198529 374786 ENSG00000176927 EFCAB5 chr17 71715903 Intergenic−18088 NM_001278587 100134391 LOC100134391 chr17 71715940 Intergenic−18051 NM_001278587 100134391 LOC100134391 chr17 71715947 Intergenic−18044 NM_001278587 100134391 LOC100134391 chr17 71715958 Intergenic−18031 NM_001278587 100134391 LOC100134391 chr17 71716005 Intergenic−17986 NM_001278587 100134391 LOC100134391 chr17 71743873 intron(NM_001278587, intron 2 of 5) 9882 NM_001278587 100134391 LOC100134391chr17 71744668 TTS (NR_027146) 10677 NM_001278587 100134391 LOC100134391chr17 71744685 TTS (NR_027146) 10694 NM_001278587 100134391 LOC100134391chr17 71744723 TTS (NR_027146) 10732 NM_001278587 100134391 LOC100134391chr17 71744739 TTS (NR_027146) 10748 NM_001278587 100134391 LOC100134391chr17 78079606 exon (NM_000152, exon 3 of 20) 4228 NM_001079803 2548ENSG00000171298 GAA chr17 78079613 exon (NM_000152, exon 3 of 20) 4235NM_001079803 2548 ENSG00000171298 GAA chr17 78079629 exon (NM_000152,exon 3 of 20) 4251 NM_001079803 2548 ENSG00000171298 GAA chr17 78079641exon (NM_000152, exon 3 of 20) 4263 NM_001079803 2548 ENSG00000171298GAA chr17 78079653 exon (NM_000152, exon 3 of 20) 4275 NM_001079803 2548ENSG00000171298 GAA chr17 78395359 intron (NR_148041, intron 1 of 6)2143 NR_039883 100616359 ENSG00000264961 MIR4730 chr17 78395376 intron(NR_148041, intron 1 of 6) 2160 NR_039883 100616359 ENSG00000264961MIR4730 chr17 80314127 Intergenic −2994 NM_207459 400629 ENSG00000182459TEX19 chr17 80314154 Intergenic −2967 NM_207459 400629 ENSG00000182459TEX19 chr17 80914812 intron (NR_135465, intron 10 of 13) 50050 NR_135466146712 ENSG00000175711 B3GNTL1 chr17 80915007 intron (NR_135465, intron10 of 13) 49855 NR_135466 146712 ENSG00000175711 B3GNTL1 chr17 80915042intron (NR_135465, intron 10 of 13) 49820 NR_135466 146712ENSG00000175711 B3GNTL1 chr17 80915160 intron (NR_135465, intron 9 of13) 49702 NR_135466 146712 ENSG00000175711 B3GNTL1 chr17 80915190 intron(NR_135465, intron 9 of 13) 49672 NR_135466 146712 ENSG00000175711B3GNTL1 chr17 80915238 exon (NM_001009905, exon 9 of 13) 49624 NR_135466146712 ENSG00000175711 B3GNTL1 chr17 80915248 exon (NM_001009905, exon 9of 13) 49614 NR_135466 146712 ENSG00000175711 B3GNTL1 chr17 80915270exon (NM_001009905, exon 9 of 13) 49591 NR_135466 146712 ENSG00000175711B3GNTL1 chr17 80915289 exon (NM_001009905, exon 9 of 13) 49573 NR_135466146712 ENSG00000175711 B3GNTL1 chr17 80915308 exon (NM_001009905, exon 9of 13) 49554 NR_135466 146712 ENSG00000175711 B3GNTL1 chr18 8659649 CpG47966 NR_120598 100287082 ENSG00000265962 GACAT2 chr18 24348426Intergenic −64826 NR_024259 728606 ENSG00000265369 PCAT18 chr18 25366256Intergenic 250347 NM_001308176 1000 ENSG00000170558 CDH2 chr18 25366262Intergenic 250341 NM_001308176 1000 ENSG00000170558 CDH2 chr18 25366300Intergenic 250303 NM_001308176 1000 ENSG00000170558 CDH2 chr18 25366309Intergenic 250294 NM_001308176 1000 ENSG00000170558 CDH2 chr18 25442175Intergenic 174428 NM_001308176 1000 ENSG00000170558 CDH2 chr18 25442224Intergenic 174379 NM_001308176 1000 ENSG00000170558 CDH2 chr18 25442243Intergenic 174360 NM_001308176 1000 ENSG00000170558 CDH2 chr18 68166868Intergenic −115043 NR_110764 101060542 ENSG00000266278 LINC01910 chr1868166878 Intergenic −115055 NR_110764 101060542 ENSG00000266278LINC01910 chr18 77320496 Intergenic −18784 NR_148949 284240 LOC284240chr18 77320538 Intergenic −18742 NR_148949 284240 LOC284240 chr1877320583 Intergenic −18697 NR_148949 284240 LOC284240 chr18 77320593Intergenic −18687 NR_148949 284240 LOC284240 chr18 77320606 Intergenic−18674 NR_148949 284240 LOC284240 chr18 77320672 Intergenic −18608NR_148949 284240 LOC284240 chr18 77320695 Intergenic −18585 NR_148949284240 LOC284240 chr18 77320711 Intergenic −18569 NR_148949 284240LOC284240 chr18 77320739 Intergenic −18541 NR_148949 284240 LOC284240chr19 883734 intron (NM_005481, intron 6 of 15) 9451 NM_005481 10025ENSG00000175221 MED16 chr19 883775 intron (NM_005481, intron 6 of 15)9410 NM_005481 10025 ENSG00000175221 MED16 chr19 883830 intron(NM_005481, intron 6 of 15) 9355 NM_005481 10025 ENSG00000175221 MED16chr19 883873 intron (NM_005481, intron 6 of 15) 9310 NM_005481 10025ENSG00000175221 MED16 chr19 883885 intron (NM_005481, intron 6 of 15)9300 NM_005481 10025 ENSG00000175221 MED16 chr19 883994 intron(NM_005481, intron 6 of 15) 9191 NM_005481 10025 ENSG00000175221 MED16chr19 884032 intron (NM_005481, intron 6 of 15) 9153 NM_005481 10025ENSG00000175221 MED16 chr19 884042 intron (NM_005481, intron 6 of 15)9143 NM_005481 10025 ENSG00000175221 MED16 chr19 884057 intron(NM_005481, intron 6 of 15) 9128 NM_005481 10025 ENSG00000175221 MED16chr19 884140 intron (NM_005481, intron 6 of 15) 9045 NM_005481 10025ENSG00000175221 MED16 chr19 884147 intron (NM_005481, intron 6 of 15)9038 NM_005481 10025 ENSG00000175221 MED16 chr19 884172 intron(NM_005481, intron 6 of 15) 9013 NM_005481 10025 ENSG00000175221 MED16chr19 884233 intron (NM_005481, intron 6 of 15) 8952 NM_005481 10025ENSG00000175221 MED16 chr19 884267 intron (NM_005481, intron 6 of 15)8918 NM_005481 10025 ENSG00000175221 MED16 chr19 884346 intron(NM_005481, intron 6 of 15) 8839 NM_005481 10025 ENSG00000175221 MED16chr19 2299058 MIR3|SINE|MIR 9093 NM_001101391 645191 ENSG00000220008LINGO3 chr19 2299180 intron (NM_001101391, intron 1 of 1) 8970NM_001101391 645191 ENSG00000220008 LINGO3 chr19 2299218 intron(NM_001101391, intron 1 of 1) 8933 NM_001101391 645191 ENSG00000220008LINGO3 chr19 2299353 intron (NM_001101391, intron 1 of 1) 8798NM_001101391 645191 ENSG00000220008 LINGO3 chr19 2299390 intron(NM_001101391, intron 1 of 1) 8761 NM_001101391 645191 ENSG00000220008LINGO3 chr19 4566603 CpG −6909 NM_032108 10501 ENSG00000167680 SEMA6Bchr19 4566636 CpG −6942 NM_032108 10501 ENSG00000167680 SEMA6B chr194566642 CpG −6951 NM_032108 10501 ENSG00000167680 SEMA6B chr19 4566653CpG −6961 NM_032108 10501 ENSG00000167680 SEMA6B chr19 9994121 intron(NM_058164, intron 1 of 5) −25272 NM_001304348 93145 ENSG00000105088OLFM2 chr19 9994137 intron (NM_058164, intron 1 of 5) −25288NM_001304348 93145 ENSG00000105088 OLFM2 chr19 9994208 intron(NM_058164, intron 1 of 5) −25359 NM_001304348 93145 ENSG00000105088OLFM2 chr19 9994219 intron (NM_058164, intron 1 of 5) −25370NM_001304348 93145 ENSG00000105088 OLFM2 chr19 9994333 intron(NM_058164, intron 1 of 5) −25484 NM_001304348 93145 ENSG00000105088OLFM2 chr19 9994349 intron (NM_058164, intron 1 of 5) −25500NM_001304348 93145 ENSG00000105088 OLFM2 chr19 13108021 intron(NM_001365982, intron 1 of 8) 1734 NM_001365982 4784 ENSG00000008441NFIX chr19 13108640 intron (NM_001365982, intron 1 of 8) 2353NM_001365982 4784 ENSG00000008441 NFIX chr19 13112778 CpG 6491NM_001365982 4784 ENSG00000008441 NFIX chr19 13616660 intron(NM_001127222, intron 1 of 46) 612 NM_001127221 773 ENSG00000141837CACNA1A chr19 13616810 exon (NM_001127221, exon 1 of 47) 462NM_001127221 773 ENSG00000141837 CACNA1A chr19 13616818 exon(NM_001127221, exon 1 of 47) 454 NM_001127221 773 ENSG00000141837CACNA1A chr19 13616834 exon (NM_001127221, exon 1 of 47) 436NM_001127221 773 ENSG00000141837 CACNA1A chr19 13616868 exon(NM_001127221, exon 1 of 47) 403 NM_001127221 773 ENSG00000141837CACNA1A chr19 13616879 exon (NM_001127221, exon 1 of 47) 393NM_001127221 773 ENSG00000141837 CACNA1A chr19 13616906 exon(NM_001127221, exon 1 of 47) 366 NM_001127221 773 ENSG00000141837CACNA1A chr19 13616911 exon (NM_001127221, exon 1 of 47) 361NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617010 exon(NM_001127221, exon 1 of 47) 262 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617018 exon (NM_001127221, exon 1 of 47) 254NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617024 exon(NM_001127221, exon 1 of 47) 248 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617029 exon (NM_001127221, exon 1 of 47) 243NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617058 5′ UTR(NM_001127221, exon 1 of 47) 214 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617065 5′ UTR (NM_001127221, exon 1 of 47) 207NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617070 5′ UTR(NM_001127221, exon 1 of 47) 199 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617082 5′ UTR (NM_001127221, exon 1 of 47) 190NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617090 5′ UTR(NM_001127221, exon 1 of 47) 172 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617128 5′ UTR (NM_001127221, exon 1 of 47) 144NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617140 5′ UTR(NM_001127221, exon 1 of 47) 130 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617157 5′ UTR (NM_001127221, exon 1 of 47) 115NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617163 5′ UTR(NM_001127221, exon 1 of 47) 109 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617169 5′ UTR (NM_001127221, exon 1 of 47) 103NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617176 promoter-TSS(NM_001127221) 96 NM_001127221 773 ENSG00000141837 CACNA1A chr1913617194 promoter-TSS (NM_001127221) 75 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617208 promoter-TSS (NM_001127221) 64 NM_001127221 773ENSG00000141837 CACNA1A chr19 13617218 promoter-TSS (NM_001127221) 54NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617233 promoter-TSS(NM_001127221) 39 NM_001127221 773 ENSG00000141837 CACNA1A chr1913617241 promoter-TSS (NM_001127221) 31 NM_001127221 773 ENSG00000141837CACNA1A chr19 13617250 promoter-TSS (NM_001127221) 22 NM_001127221 773ENSG00000141837 CACNA1A chr19 13617265 promoter-TSS (NM_001127221) 7NM_001127221 773 ENSG00000141837 CACNA1A chr19 13617288 promoter-TSS(NM_001127221) 3 NM_001174080 773 ENSG00000141837 CACNA1A chr19 13617302promoter-TSS (NM_001127221) −11 NM_001127222 773 ENSG00000141837 CACNA1Achr19 13617315 promoter-TSS (NM_001127221) −24 NM_001127222 773ENSG00000141837 CACNA1A chr19 13617321 promoter-TSS (NM_001127221) −30NM_001127222 773 ENSG00000141837 CACNA1A chr19 13617328 promoter-TSS(NM_001127221) −37 NM_001127222 773 ENSG00000141837 CACNA1A chr1913617336 promoter-TSS (NM_001127221) −45 NM_001127222 773ENSG00000141837 CACNA1A chr19 13617364 promoter-TSS (NM_001127221) −73NM_001127222 773 ENSG00000141837 CACNA1A chr19 13617380 promoter-TSS(NM_001127221) −89 NM_001127222 773 ENSG00000141837 CACNA1A chr1913617419 promoter-TSS (NM_001127221) −128 NM_001127222 773ENSG00000141837 CACNA1A chr19 13617465 promoter-TSS (NM_001127221) −174NM_001127222 773 ENSG00000141837 CACNA1A chr19 13617483 promoter-TSS(NM_001127221) −195 NM_001127222 773 ENSG00000141837 CACNA1A chr1913617503 promoter-TSS (NM_001127221) −212 NM_001127222 773ENSG00000141837 CACNA1A chr19 13617512 promoter-TSS (NM_001127221) −221NM_001127222 773 ENSG00000141837 CACNA1A chr19 13617517 promoter-TSS(NM_001127221) −226 NM_001127222 773 ENSG00000141837 CACNA1A chr1913617541 promoter-TSS (NM_001127221) −250 NM_001127222 773ENSG00000141837 CACNA1A chr19 13618356 Intergenic −1065 NM_001127222 773ENSG00000141837 CACNA1A chr19 13618391 Intergenic −1101 NM_001127222 773ENSG00000141837 CACNA1A chr19 13700379 MER58B|DNA|hAT-Charlie −83088NM_001127222 773 ENSG00000141837 CACNA1A chr19 18836689 intron(NM_001098482, intron 1 of 14) 42201 NM_001098482 23373 ENSG00000105662CRTC1 chr19 18837043 intron (NM_001098482, intron 1 of 14) 42556NM_001098482 23373 ENSG00000105662 CRTC1 chr19 18837091 intron(NM_001098482, intron 1 of 14) 42603 NM_001098482 23373 ENSG00000105662CRTC1 chr19 18837098 intron (NM_001098482, intron 1 of 14) 42610NM_001098482 23373 ENSG00000105662 CRTC1 chr19 18837105 intron(NM_001098482, intron 1 of 14) 42617 NM_001098482 23373 ENSG00000105662CRTC1 chr19 34181556 intron (NM_001127895, intron 3 of 4) 6124 NM_02246764377 ENSG00000124302 CHST8 chr19 34181606 intron (NM_001127895, intron3 of 4) 6174 NM_022467 64377 ENSG00000124302 CHST8 chr19 34181636 intron(NM_001127895, intron 3 of 4) 6204 NM_022467 64377 ENSG00000124302 CHST8chr19 38527887 L2b|LINE|L2 −125847 NR_145800 109623473 SNORD152 chr1938527913 L2b|LINE|L2 −125821 NR_145800 109623473 SNORD152 chr19 38527932L2b|LINE|L2 −125802 NR_145800 109623473 SNORD152 chr19 38528016L2b|LINE|L2 −125718 NR_145800 109623473 SNORD152 chr19 38528031L2b|LINE|L2 −125701 NR_145800 109623473 SNORD152 chr19 38684235 exon(NM_015073, exon 18 of 22) 30501 NR_145800 109623473 SNORD152 chr1938684327 exon (NM_015073, exon 18 of 22) 30561 NM_001135155 8193ENSG00000011332 DPF1 chr19 38684338 exon (NM_015073, exon 18 of 22)30550 NM_001135155 8193 ENSG00000011332 DPF1 chr19 38684363 exon(NM_015073, exon 18 of 22) 30522 NM_001135155 8193 ENSG00000011332 DPF1chr19 48699558 exon (NM_199341, exon 4 of 4) 25623 NM_199341 374920ENSG00000185453 ZSWIM9 chr19 48699578 exon (NM_199341, exon 4 of 4)25643 NM_199341 374920 ENSG00000185453 ZSWIM9 chr19 48699588 exon(NM_199341, exon 4 of 4) 25653 NM_199341 374920 ENSG00000185453 ZSWIM9chr19 48699615 exon (NM_199341, exon 4 of 4) 25680 NM_199341 374920ENSG00000185453 ZSWIM9 chr19 48699628 exon (NM_199341, exon 4 of 4)25693 NM_199341 374920 ENSG00000185453 ZSWIM9 chr19 48699667 exon(NM_199341, exon 4 of 4) 25733 NM_199341 374920 ENSG00000185453 ZSWIM9chr19 48699717 exon (NM_199341, exon 4 of 4) 25782 NM_199341 374920ENSG00000185453 ZSWIM9 chr19 55870392 exon (NM_001145402, exon 9 of 11)4234 NM_001145402 284418 ENSG00000180043 FAM71E2 chr19 55870402 exon(NM_001145402, exon 9 of 11) 4224 NM_001145402 284418 ENSG00000180043FAM71E2 chr19 55870407 exon (NM_001145402, exon 9 of 11) 4219NM_001145402 284418 ENSG00000180043 FAM71E2 chr19 55870425 exon(NM_001145402, exon 9 of 11) 4201 NM_001145402 284418 ENSG00000180043FAM71E2 chr19 55870439 exon (NM_001145402, exon 9 of 11) 4187NM_001145402 284418 ENSG00000180043 FAM71E2 chr19 55870456 exon(NM_001145402, exon 9 of 11) 4170 NM_001145402 284418 ENSG00000180043FAM71E2 chr19 55870462 exon (NM_001145402, exon 9 of 11) 4164NM_001145402 284418 ENSG00000180043 FAM71E2 chr19 55870471 exon(NM_001145402, exon 9 of 11) 4155 NM_001145402 284418 ENSG00000180043FAM71E2 chr19 55870886 exon (NM_001145402, exon 9 of 11) 3740NM_001145402 284418 ENSG00000180043 FAM71E2 chr20 20180688 intron(NM_015585, intron 17 of 26) 143401 NM_001167816 26074 ENSG00000089101CFAP61 chr20 20180732 intron (NM_015585, intron 17 of 26) 143444NM_001167816 26074 ENSG00000089101 CFAP61 chr20 20188098 intron(NM_015585, intron 17 of 26) 150810 NM_001167816 26074 ENSG00000089101CFAP61 chr20 20188151 intron (NM_015585, intron 17 of 26) 150863NM_001167816 26074 ENSG00000089101 CFAP61 chr20 20206077 intron(NM_015585, intron 17 of 26) −142669 NM_002196 3642 ENSG00000173404INSM1 chr20 20232312 exon (NM_015585, exon 20 of 27) −116434 NM_0021963642 ENSG00000173404 INSM1 chr20 20232336 exon (NM_015585, exon 20 of27) −116410 NM_002196 3642 ENSG00000173404 INSM1 chr20 20232350 exon(NM_015585, exon 20 of 27) −116394 NM_002196 3642 ENSG00000173404 INSM1chr20 20232360 exon (NM_015585, exon 20 of 27) −116386 NM_002196 3642ENSG00000173404 INSM1 chr20 20232370 exon (NM_015585, exon 20 of 27)−116376 NM_002196 3642 ENSG00000173404 INSM1 chr20 20232391 exon(NM_015585, exon 20 of 27) −116355 NM_002196 3642 ENSG00000173404 INSM1chr20 20376947 intron (NM_020343, intron 39 of 39) 28201 NM_002196 3642ENSG00000173404 INSM1 chr20 20376962 intron (NM_020343, intron 39 of 39)28216 NM_002196 3642 ENSG00000173404 INSM1 chr20 20377074 intron(NM_020343, intron 39 of 39) 28328 NM_002196 3642 ENSG00000173404 INSM1chr20 20377089 intron (NM_020343, intron 39 of 39) 28343 NM_002196 3642ENSG00000173404 INSM1 chr20 20377110 intron (NM_020343, intron 39 of 39)28364 NM_002196 3642 ENSG00000173404 INSM1 chr20 20377122 intron(NM_020343, intron 39 of 39) 28376 NM_002196 3642 ENSG00000173404 INSM1chr20 20377130 intron (NM_020343, intron 39 of 39) 28384 NM_002196 3642ENSG00000173404 INSM1 chr20 20377162 intron (NM_020343, intron 39 of 39)28416 NM_002196 3642 ENSG00000173404 INSM1 chr20 20377169 intron(NM_020343, intron 39 of 39) 28423 NM_002196 3642 ENSG00000173404 INSM1chr20 20377206 intron (NM_020343, intron 39 of 39) 28460 NM_002196 3642ENSG00000173404 INSM1 chr20 20392139 intron (NM_020343, intron 38 of 39)43396 NM_002196 3642 ENSG00000173404 INSM1 chr20 20392184 intron(NM_020343, intron 38 of 39) 43438 NM_002196 3642 ENSG00000173404 INSM1chr20 20392215 intron (NM_020343, intron 38 of 39) 43469 NM_002196 3642ENSG00000173404 INSM1 chr20 20392408 intron (NM_020343, intron 38 of 39)43662 NM_002196 3642 ENSG00000173404 INSM1 chr20 20421295 intron(NM_020343, intron 37 of 39) 72549 NM_002196 3642 ENSG00000173404 INSM1chr20 20421314 intron (NM_020343, intron 37 of 39) 72568 NM_002196 3642ENSG00000173404 INSM1 chr20 20421345 intron (NM_020343, intron 37 of 39)72599 NM_002196 3642 ENSG00000173404 INSM1 chr20 20421371 intron(NM_020343, intron 37 of 39) 72627 NM_002196 3642 ENSG00000173404 INSM1chr20 20421396 intron (NM_020343, intron 37 of 39) 72650 NM_002196 3642ENSG00000173404 INSM1 chr20 20421420 intron (NM_020343, intron 37 of 39)72675 NM_002196 3642 ENSG00000173404 INSM1 chr20 20421459 intron(NM_020343, intron 37 of 39) 72713 NM_002196 3642 ENSG00000173404 INSM1chr20 20421486 intron (NM_020343, intron 37 of 39) 72740 NM_002196 3642ENSG00000173404 INSM1 chr20 31129481 intron (NM_001256798, intron 1 of10) 31721 NR_110619 101929698 ENSG00000277301 LOC01929698 chr20 36923352Intergenic −9198 NM_001725 671 ENSG00000101425 BPI chr20 36923369MIRb|SINE|MIR −9178 NM_001725 671 ENSG00000101425 BPI chr20 36923397MIRb|SINE|MIR −9153 NM_001725 671 ENSG00000101425 BPI chr20 61013054intron (NR_033263, intron 7 of 7) −10461 NM_080833 140893ENSG00000130701 RBBP8NL chr20 61013094 intron (NR_033263, intron 7 of 7)−10501 NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61013113 intron(NR_033263, intron 7 of 7) −10520 NM_080833 140893 ENSG00000130701RBBP8NL chr20 61013148 intron (NR_033263, intron 7 o7) −10555 NM_080833140893 ENSG00000130701 RBBP8NL chr20 61013167 intron (NR_033263, intron7 o7) −10574 NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61013187intron (NR_033263, intron 7 of 7) −10596 NM_080833 140893ENSG00000130701 RBBP8NL chr20 61013226 intron (NR_033263, intron 7 of 7)−10633 NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61013242 intron(NR_033263, intron 7 of 7) −10649 NM_080833 140893 ENSG00000130701RBBP8NL chr20 61013251 intron (NR_033263, intron 7 of 7) −10658NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61013263 intron(NR_033263, intron 7 of 7) −10670 NM_080833 140893 ENSG00000130701RBBP8NL chr20 61013303 intron (NR_033263, intron 7 of 7) −10710NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61013339 intron(NR_033263, intron 7 of 7) −10747 NM_080833 140893 ENSG00000130701RBBP8NL chr20 61013474 intron (NR_033263, intron 7 of 7) −10881NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61013515 intron(NR_033263, intron 7 of 7) −10922 NM_080833 140893 ENSG00000130701RBBP8NL chr20 61020520 intron (NR_033263, intron 7 of 7) −17927NM_080833 140893 ENSG00000130701 RBBP8NL chr20 61021747 intron(NR_033263, intron 7 of 7) −19154 NM_080833 140893 ENSG00000130701RBBP8NL chr21 43442046 promoter-TSS (NR_119385) −65 NR_119385 150142ENSG00000237232 ZNF295-AS1 chr21 43442055 promoter-TSS (NR_119385) −56NR_119385 150142 ENSG00000237232 ZNF295-AS1 chr21 43442083 promoter-TSS(NR_119385) −28 NR_119385 150142 ENSG00000237232 ZNF295-AS1 chr2143442252 promoter-TSS (NR_027273) −124 NR_027273 150142 ENSG00000237232ZNF295-AS1 chr21 43442338 promoter-TSS (NR_027273) −38 NR_027273 150142ENSG00000237232 ZNF295-AS1 chr21 43442384 promoter-TSS (NR_027273) 8NR_027273 150142 ENSG00000237232 ZNF295-AS1 chr21 44836763 exon(NM_001320643, exon 14 of 14) 10246 NM_173354 150094 ENSG00000142178SIK1 chr21 44836797 exon (NM_001320643, exon 14 of 14) 10212 NM_173354150094 ENSG00000142178 SIK1 chr21 144836823 exon (NM_001320643, exon 14of 14) 10186 NM_173354 150094 ENSG00000142178 SIK1 chr21 44836842 exon(NM_001320643, exon 14 of 14) 10167 NM_173354 150094 ENSG00000142178SIK1 chr21 44836924 exon (NM_001320643, exon 14 of 14) 10085 NM_173354150094 ENSG00000142178 SIK1 chr21 44836936 exon (NM_001320643, exon 14of 14) 10073 NM_173354 150094 ENSG00000142178 SIK1 chr21 44836971 exon(NM_001320643, exon 14 of 14) 10038 NM_173354 150094 ENSG00000142178SIK1 chr21 44837026 CpG 9980 NM_173354 150094 ENSG00000142178 SIK1 chr2144837044 CpG 9965 NM_173354 150094 ENSG00000142178 SIK1 chr21 44837052CpG 9957 NM_173354 150094 ENSG00000142178 SIK1 chr21 44837060 CpG 9949NM_173354 150094 ENSG00000142178 SIK1 chr21 44837074 CpG 9933 NM_173354150094 ENSG00000142178 SIK1 chr21 44837115 CpG 9894 NM_173354 150094ENSG00000142178 SIK1 chr21 44837132 CpG 9876 NM_173354 150094ENSG00000142178 SIK1 chr21 44837157 CpG 9852 NM_173354 150094ENSG00000142178 SIK1 chr21 145653981 intron (NM_015259, intron 4 of 6)6843 NM_001283050 23308 ENSG00000160223 ICOSLG chr21 45654156 intron(NM_015259, intron 4 of 6) 6668 NM_001283050 23308 ENSG00000160223ICOSLG chr22 47444997 intron (NM_014346, intron 11 of 12) −133061NR_122047 642757 ENSG00000280080 TBC1D22A-AS1 chr22 47445037 intron(NM_014346, intron 11 of 12) −133101 NR_122047 642757 ENSG00000280080TBC1D22A-AS1 chr22 47447406 intron (NM_014346, intron 11 of 12) −135470NR_122047 642757 ENSG00000280080 TBC1D22A-AS1 chr22 47447603 intron(NM_014346, intron 11 of 12) −135667 NR_122047 642757 ENSG00000280080TBC1D22A-AS1 chrX 104458760 L1PA8|LINE|L1 6615 NM_031274 56157ENSG00000268629 TEX13A chrX 104692650 AluSq2|SINE|Alu −227275NM_001291277 56157 ENSG00000268629 TEX13A chrX 104804571 AlnSq2|SINE|Alu−261959 NM_198465 203447 ENSG00000123572 NRK chrX 104891135LTR17|LTR|ERV1 −175395 NM_198465 203447 ENSG00000123572 NRK chrX105016634 AluSg|SINE|Alu −49896 NM_198465 203447 ENSG00000123572 NRKchrX 105016672 AluSg|SINE|Alu −49858 NM_198465 203447 ENSG00000123572NRK chrX 128926432 exon (NM_018990, exon 5 of 8) 12509 NM_018990 54440ENSG00000122122 SASH3 chr2 209103955 intron (NM_005896, intron 8 of 9)15057 NM_001282387 3417 ENSG00000138413 IDH1 chr4 106155150 exon(NM_001127208, exon 3 of 11) 87323 NM_001127208 54790 ENSG00000168769TET2 chr4 106155913 exon (NM_001127208, exon 3 of 11) 88086 NM_00112720854790 ENSG00000168769 TET2 chr4 106156460 exon (NM_001127208, exon 3 of11) 88633 NM_001127208 54790 ENSG00000168769 TET2 chr4 106156742 exon(NM_001127208, exon 3 of 11) 88915 NM_001127208 54790 ENSG00000168769TET2 chr4 106157415 exon (NM_001127208, exon 3 of 11) 89588 NM_00112720854790 ENSG00000168769 TET2 chr4 106164901 TTS (NM_017628) 97074NM_001127208 54790 ENSG00000168769 TET2 chr4 106196236 exon(NM_001127208, exon 11 of 11) 77787 NR_126420 104384744 TET2-AS1 chr733732332 Intergenic −212165 NM_133468 168667 ENSG00000164619 BMPER chr7140453119 exon (NM_004333, exon 15 of 18) −56257 NR_024454 100134713ENSG00000240889 NDUFB2-AS1 chr7 140481387 exon (NM_004333, exon 11 of18) −84525 NR_024454 100134713 ENSG00000240889 NDUFB2-AS1 chr7 140481426exon (NM_004333, exon 11 of 18) −84564 NR_024454 100134713ENSG00000240889 NDUFB2-AS1 chr7 140500421 intron (NR_148928, intron 7 of17) −103559 NR_024454 100134713 ENSG00000240889 NDUFB2-AS1 chr7140507748 exon (NM_004333, exon 5 of 18) −110886 NR_024454 100134713ENSG00000240889 NDUFB2-AS1 chr7 140507954 intron (NM_001354609, intron 4of 18) −111092 NR_024454 100134713 ENSG00000240889 NDUFB2-AS1 chr7140624441 exon (NM_004333, exon 1 of 18) 273 NM_001354609 673ENSG00000157764 BRAF chr14 38061176 exon (NM_004496, exon 2 of 2) 3252NM_004496 3169 ENSG00000129514 FOXA1 chr14 38061319 exon (NM_004496,exon 2 of 2) 3120 NM_004496 3169 ENSG00000129514 FOXA1 chr14 38061830exon (NM_004496, exon 2 of 2) 2609 NM_004496 3169 ENSG00000129514 FOXA1chr17 7572948 exon (NM_000546, exon 11 of 11) 5599 NM_001276698 7157ENSG00000141510 TP53 chr17 7573967 exon (NM_000546, exon 10 of 11) 4554NM_001276698 7157 ENSG00000141510 TP53 chr17 7576524 exon (NM_001126117,exon 6 of 8) 2022 NM_001276698 7157 ENSG00000141510 TP53 chr17 7576838exon (NM_001126117, exon 5 of 8) 1672 NM_001276698 7157 ENSG00000141510TP53 chr17 7577020 exon (NM_001126117, exon 4 of 8) 1474 NM_0012766987157 ENSG00000141510 TP53 chr17 7577483 exon (NM_001126117, exon 3 of 8)1008 NM_001276698 7157 ENSG00000141510 TP53 chr17 7578161 exon(NM_001126117, exon 2 of 8) 337 NM_001276698 7157 ENSG00000141510 TP53chr17 7578373 promoter-TSS (NM_001276697) 90 NM_001276698 7157ENSG00000141510 TP53 chr17 7579297 promoter-TSS (NM_001126117) −519NM_001126116 7157 ENSG00000141510 TP53 chr17 7579393 promoter-TSS(NM_001126117) −601 NM_001126116 7157 ENSG00000141510 TP53 chr17 7579506promoter-TSS (NM_001126117) −710 NM_001126116 7157 ENSG00000141510 TP53chr17 7579701 promoter-TSS (NM_001126117) −905 NM_001126116 7157ENSG00000141510 TP53 chr17 7579846 exon (NM_000546, exon 2 of 11) −1050NM_001126116 7157 ENSG00000141510 TP53 chr17 47696409 exon(NM_001007228, exon 5 of 10) 7515 NM_001370732 8405 ENSG00000121067 SPOPchr17 47696673 exon (NM_001007228, exon 4 of 10) 7263 NM_001370732 8405ENSG00000121067 SPOP chr20 31375142 exon (NM_175848, exon 6 of 22) 7499NM_175850 1789 ENSG00000088305 DNMT3B chr20 31380384 intron (NM_175849,intron 8 of 19) 12741 NM_175850 1789 ENSG00000088305 DNMT3B chr2031381300 Kanga11a|DNA|TcMar-Tc2 13657 NM_175850 1789 ENSG00000088305DNMT3B chr20 31386255 exon (NM_175848, exon 14 of 22) 18612 NM_1758501789 ENSG00000088305 DNMT3B chr20 31388050 exon (NM_175848, exon 16 of22) −19695 NM_012325 22919 ENSG00000101367 MAPRE1 chr20 31389120 exon(NM_175848, exon 18 of 22) −18625 NM_012325 22919 ENSG00000101367 MAPRE1chr20 31393185 exon (NM_175848, exon 20 of 22) −14560 NM_012325 22919ENSG00000101367 MAPRE1 chr20 31395662 exon (NM_175848, exon 22 of 22)−12083 NM_012325 22919 ENSG00000101367 MAPRE1 chrX 66121000 Intergenic−262860 NM_001199687 60401 ENSG00000131080 EDA2R chrX 66766332 exon(NM_001348064, exon 1 of 3) 1882 NM_001011645 367 ENSG00000169083 ARchrX 66931448 exon (NM_000044, exon 4 of 8) 166998 NM_001011645 367ENSG00000169083 AR chrX 66937357 exon (NM_000044exon 5 of 8) 172907NM_001011645 367 ENSG00000169083 AR chrX 66943528 exon (NM_000044, exon8 of 8) 179082 NM_001011645 367 ENSG00000169083 AR chr2 25452399non-coding (NR_135490, exon 24 of 24) 22596 NM_001320893 1788ENSG00000119772 DNMT3A chr2 25452969 non-coding (NR_135490, exon 24 of24) 22026 NM_001320893 1788 ENSG00000119772 DNMT3A chr2 25453099non-coding (NR_135490, exon 24 of 24) 21896 NM_001320893 1788ENSG00000119772 DNMT3A chr2 25453105 non-coding (NR_135490, exon 24 of24) 21890 NM_001320893 1788 ENSG00000119772 DNMT3A chr2 25453799non-coding (NR_135490, exon 24 of 24) 21196 NM_001320893 1788ENSG00000119772 DNMT3A chr2 25453898 non-coding (NR_135490, exon 24 of24) 21097 NM_001320893 1788 ENSG00000119772 DNMT3A chr2 25453899non-coding (NR_135490, exon 24 of 24) 21096 NM_001320893 1788ENSG00000119772 DNMT3A chr2 25453913 non-coding (NR_135490, exon 24 of24) 21082 NM_001320893 1788 ENSG00000119772 DNMT3A chr2 25499982 CpG−24803 NM_153759 1788 ENSG00000119772 DNMT3A chr2 25500271 CpG −25092NM_153759 1788 ENSG00000119772 DNMT3A chr2 25500272 CpG −25093 NM_1537591788 ENSG00000119772 DNMT3A chr2 239147428 3′ UTR (NM_018645, exon 4 of4) 1246 NM_018645 55502 ENSG00000144485 HES6 chr2 239147440 3′ UTR(NM_018645, exon 4 of 4) 1234 NM_018645 55502 ENSG00000144485 HES6 chr2239147441 3′ UTR (NM_018645, exon 4 of 4) 1233 NM_018645 55502ENSG00000144485 HES6 chr2 239147485 exon (NM_018645, exon 4 of 4) 1189NM_018645 55502 ENSG00000144485 HES6 chr2 239147486 exon (NM_018645,exon 4 of 4) 1188 NM_018645 55502 ENSG00000144485 HES6 chr2 239147522exon (NM_018645, exon 4 of 4) 1152 NM_018645 55502 ENSG00000144485 HES6chr2 239147534 exon (NM_018645, exon 4 of 4) 1140 NM_018645 55502ENSG00000144485 HES6 chr2 239147589 exon (NM_018645, exon 4 of 4) 1085NM_018645 55502 ENSG00000144485 HES6 chr2 239147601 exon (NM_018645,exon 4 of 4) 1073 NM_018645 55502 ENSG00000144485 HES6 chr2 239147614exon (NM_018645, exon 4 of 4) 1060 NM_018645 55502 ENSG00000144485 HES6chr2 239147637 exon (NM_018645, exon 4 of 4) 1037 NM_018645 55502ENSG00000144485 HES6 chr2 239147649 exon (NM_018645, exon 4 of 4) 1025NM_018645 55502 ENSG00000144485 HES6 chr2 239147665 exon (NM_018645,exon 4 of 4) 1009 NM_018645 55502 ENSG00000144485 HES6 chr2 239149894CpG-16151 −1220 NM_001142853 55502 ENSG00000144485 HES6 chr2 239149895CpG-16151 −1221 NM_001142853 55502 ENSG00000144485 HES6 chr3 12838468CpG 294 NM_012298 23066 ENSG00000144712 CAND2 chr3 50660608 intron(NM_001243925, intron 2 of 10) 6031 NM_001243925 7867 ENSG00000114738MAPKAPK3 chr3 50670155 intron (NM_001243925, intron 2 of 10) 15578NM_001243925 7867 ENSG00000114738 MAPKAPK3 chr3 128202781 exon(NM_032638, exon 4 of 6) 3978 NM_001145662 2624 ENSG00000179348 GATA2chr3 128202787 exon (NM_032638, exon 4 of 6) 3972 NM_001145662 2624ENSG00000179348 GATA2 chr3 128202792 exon (NM_032638, exon 4 of 6) 3967NM_001145662 2624 ENSG00000179348 GATA2 chr3 128202795 exon (NM_032638,exon 4 of 6) 3964 NM_001145662 2624 ENSG00000179348 GATA2 chr3 128202796exon (NM_032638, exon 4 of 6) 3963 NM_001145662 2624 ENSG00000179348GATA2 chr3 128202884 intron (NM_001145661, intron 4 of 6) 3875NM_001145662 2624 ENSG00000179348 GATA2 chr3 128202894 intron(NM_001145661, intron 4 of 6) 3865 NM_001145662 2624 ENSG00000179348GATA2 chr3 128202895 intron (NM_001145661, intron 4 of 6) 3864NM_001145662 2624 ENSG00000179348 GATA2 chr3 128202927 intron(NM_001145661, intron 4 of 6) 3832 NM_001145662 2624 ENSG00000179348GATA2 chr3 128202928 intron (NM_001145661, intron 4 of 6) 3831NM_001145662 2624 ENSG00000179348 GATA2 chr3 128205157 exon (NM_032638,exon 3 of 6) 1602 NM_001145662 2624 ENSG00000179348 GATA2 chr3 128205179exon (NM_032638, exon 3 of 6) 1580 NM_001145662 2624 ENSG00000179348GATA2 chr3 128205180 exon (NM_032638, exon 3 of 6) 1579 NM_0011456622624 ENSG00000179348 GATA2 chr3 128205195 exon (NM_032638, exon 3 of 6)1564 NM_001145662 2624 ENSG00000179348 GATA2 chr3 128205196 exon(NM_032638, exon 3 of 6) 1563 NM_001145662 2624 ENSG00000179348 GATA2chr3 128205210 intron (NM_001145661, intron 3 of 6) 1549 NM_0011456622624 ENSG00000179348 GATA2 chr3 128210723 CpG-18893 1302 NM_032638 2624ENSG00000179348 GATA2 chr3 128210727 CpG-18893 1298 NM_032638 2624ENSG00000179348 GATA2 chr3 128212207 promoter-TSS (NM_032638) −182NM_032638 2624 ENSG00000179348 GATA2 chr3 185817004 intron (NM_004454,intron 5 of 12) 9869 NM_004454 2119 ENSG00000244405 ETV5 chr4 16084875promoter-TSS (NM_001371407) 79 NM_001371406 chr4 16084881 promoter-TSS(NM_001371407) 73 NM_001371406 chr4 16084898 promoter-TSS (NM_001371407)56 NM_001371406 chr4 16085260 promoter-TSS (NM_001145852) 87NM_001145847 8842 ENSG00000007062 PROM1 chr4 16085380 promoter-TSS(NM_001145852) −33 NM_00145852 8842 ENSG00000007062 PROM1 chr4 16085396promoter-TSS (NM_001145852) −49 NM_001145852 8842 ENSG00000007062 PROM1chr4 16085398 promoter-TSS (NM_001145852) −51 NM_001145852 8842ENSG00000007062 PROM1 chr4 16085401 promoter-TSS (NM_001145852) −54NM_001145852 8842 ENSG00000007062 PROM1 chr5 172661872 exon (NM_004387,exon 1 of 2) 332 NM_001166175 1482 ENSG00000183072 NKX2-5 chr5 172661874exon (NM_004387, exon 1 of 2) 330 NM_001166175 1482 ENSG00000183072NKX2-5 chr6 34522044 intron (NM_012391, intron 1 of 5) 2057 NM_01239125803 ENSG00000124664 SPDEF chr6 34523223 intron (NM_012391, intron 1 of5) 878 NM_012391 25803 ENSG00000124664 SPDEF chr8 11561726 promoter-TSS(NM_002052) 20 NM_002052 2626 ENSG00000136574 GATA4 chr8 11565855 exon(NM_002052, exon 2 of 7) 495 NM_001308093 2626 ENSG00000136574 GATA4chr8 11566229 exon (NM_002052, exon 2 of 7) 869 NM_001308093 2626ENSG00000136574 GATA4 chr8 11583613 intron (NM_002052, intron 2 of 6)18253 NM_001308093 2626 ENSG00000136574 GATA4 chr8 11583614 intron(NM_002052, intron 2 of 6) 18254 NM_001308093 2626 ENSG00000136574 GATA4chr9 126775063 CpG 1021 NM_004789 9355 ENSG00000106689 LHX2 chr9126775082 CpG 1040 NM_004789 9355 ENSG00000106689 LHX2 chr9 126776013CpG 1971 NM_004789 9355 ENSG00000106689 LHX2 chr9 126776231 CpG 2189NM_004789 9355 ENSG00000106689 LHX2 chr9 139437635 intron (NM_017617,intron 2 of 33) 2860 NM_017617 4851 ENSG00000148400 NOTCH1 chr9139437679 intron (NM_017617, intron 2 of 33) 2816 NM_017617 4851ENSG00000148400 NOTCH1 chr10 23481414 5′ UTR (NM_178161, exon 1 of 2)178 NM_178161 256297 ENSG00000168267 PTF1A chr10 23481415 5′ UTR(NM_178161, exon 1 of 2) 179 NM_178161 256297 ENSG00000108267 PTF1Achr10 23481417 5′ UTR (NM_178161, exon 1 of 2) 181 NM_178161 256297ENSG00000168267 PTF1A chr10 23481445 5′ UTR (NM_178161, exon 1 of 2) 209NM_178161 256297 ENSG00000168267 PTF1A chr10 23481447 5′ UTR (NM_178161,exon 1 of 2) 211 NM_178161 256297 ENSG00000168267 PTF1A chr10 234814485′ UTR (NM_178161, exon 1 of 2) 212 NM_178161 256297 ENSG00000168267PTF1A chr10 23481451 5′ UTR (NM_178161, exon 1 of 2) 215 NM_178161256297 ENSG00000168267 PTF1A chr10 23481461 exon (NM_178161, exon 1 of2) 225 NM_178161 256297 ENSG00000168267 PTF1A chr10 23481462 exon(NM_78161, exon 1 of 2) 226 NM_178161 256297 ENSG00000168267 PTF1A chr1023481463 exon (NM_178161, exon 1 of 2) 227 NM_178161 256297ENSG00000168267 PTF1A chr10 56699066 AluY|SINE|Alu −138020 NM_00114276765217 ENSG00000150275 PCDH15 chr10 56699077 AluY|SINE|Alu −138031NM_001142767 65217 ENSG00000150275 PCDH15 chr10 57391015 CpG −3318NM_001354404 65217 ENSG00000150275 PCDH15 chr11 69451450 CpG −4418NM_053056 595 ENSG00000110092 CCND1 chr12 103344993 intron(NM_001354304, intron 1 of 13) −6454 NM_004316 429 ENSG00000139352 ASCL1chr12 103344998 intron (NM_001354304, intron 1 of 13) −6449 NM_004316429 ENSG00000139352 ASCL1 chr12 103345006 intron (NM_001354304, intron 1of 13) −6441 NM_004316 429 ENSG00000139352 ASCL1 chr12 103345029 intron(NM_001354304, intron 1 of 13) −6418 NM_004316 429 ENSG00000139352 ASCL1chr12 103345033 intron (NM_001354304, intron 1 of 13) −6414 NM_004316429 ENSG00000139352 ASCL1 chr14 51560040 intron (NM_052978, intron 1 of6) 2377 NM_015163 114088 ENSG00000100505 TRIM9 chr14 51560162 CpG 2255NM_015163 114088 ENSG00000100505 TRIM9 chr14 51560191 CpG 2226 NM_015163114088 ENSG00000100505 TRIM9 chr14 51560193 CpG 2224 NM_015163 114088ENSG00000100505 TRIM9 chr14 51560208 CpG 2209 NM_015163 114088ENSG00000100505 TRIM9 chr14 51560259 CpG 2158 NM_015163 114088ENSG00000100505 TRIM9 chr14 51560261 CpG 2156 NM_015163 114088ENSG00000100505 TRIM9 chr14 51560275 CpG 2142 NM_015163 114088ENSG00000100505 TRIM9 chr14 65409361 promoter-TSS (NM_002083) 97NR_046321 2877 ENSG00000176153 GPX2 chr14 93385930 Intergenic −3560NM_001301690 1113 ENSG00000100604 CHGA chr14 93423499 intron(NM_001142593, intron 8 of 10) 34009 NM_001275 1113 ENSG00000100604 CHGAchr14 93423555 intron (NM_001142593, intron 8 of 10) 34065 NM_0012751113 ENSG00000100604 CHGA chr14 93425158 intron (NM_001142593, intron 7of 10) 35668 NM_001275 1113 ENSG00000100604 CHGA chr14 93425189MIRb|SINE|MIR 35699 NM_001275 1113 ENSG00000100604 CHGA chr14 93425207MIRb|SINE|MIR 35717 NM_001275 1113 ENSG00000100604 CHGA chr14 93425289MIRb|SINE|MIR 35799 NM_001275 1113 ENSG00000100604 CHGA chr14 93425328MIRb|SINE|MIR 35838 NM_001275 1113 ENSG00000100604 CHGA chr14 93425517intron (NM_001142593, intron 7 of 10) 36027 NM_001275 1113ENSG00000100604 CHGA chr14 93425684 intron (NM_001142593, intron 7 of10) 36194 NM_001275 1113 ENSG00000100604 CHGA chr14 93425685 intron(NM_001142593, intron 7 of 10) 36195 NM_001275 1113 ENSG00000100604 CHGAchr14 93425738 intron (NM_001142593, intron 7 of 10) 36248 NM_0012751113 ENSG00000100604 CHGA chr14 93426226 intron (NM_001142593, intron 7of 10) 36736 NM_001275 1113 ENSG00000100604 CHGA chr14 93426244 intron(NM_001142593, intron 7 of 10) 36754 NM_001275 1113 ENSG00000100604 CHGAchr14 93426333 intron (NM_001142593, intron 7 of 10) 36843 NM_0012751113 ENSG00000100604 CHGA chr14 93426378 intron (NM_001142593, intron 7of 10) 36888 NM_001275 1113 ENSG00000100604 CHGA chr14 93426872MIRb|SINE|MIR 37382 NM_001275 1113 ENSG00000100604 CHGA chr14 93426913MIRb|SINE|MIR 37423 NM_001275 1113 ENSG00000100604 CHGA chr14 93426914MIRb|SINE|MIR 37424 NM_001275 1113 ENSG00000100604 CHGA chr14 93426959intron (NM_001142593, intron 7 of 10) 37469 NM_001275 1113ENSG00000100604 CHGA chr14 93439910 intron (NM_001142593, intron 5 of10) 50420 NM_001275 1113 ENSG00000100604 CHGA chr18 31323189 exon(NM_030632, exon 12 of 12) 165011 NM_030632 80816 ENSG00000141431 ASXL3chr18 31323202 exon (NM_030632, exon 12 of 12) 165024 NM_030632 80816ENSG00000141431 ASXL3 chr18 53175324 intron (NM_001369572, intron 3 of19) 2674 NM_001348211 6925 ENSG00000196628 TCF4 chr18 53305364AluJb|SINE|Alu −2181 NM_001243226 6925 ENSG00000196628 TCF4 chr1853305490 AluJb|SINE|Alu −2307 NM_001243226 6925 ENSG00000196628 TCF4chr19 11086495 intron (NM_003072, intron 1 of 34) −8328 NM_0011288466597 ENSG00000127616 SMARCA4 chr19 39993532 exon (NM_016941, exon 4 of8) 3950 NM_203486 10683 ENSG00000090932 DLL3 chr19 39993551 exon(NM_016941, exon 4 of 8) 3969 NM_203486 10683 ENSG00000090932 DLL3 chr1939993567 exon (NM_016941, exon 4 of 8) 3985 NM_203486 10683ENSG00000090932 DLL3 chr19 39993606 exon (NM_016941, exon 4 of 8) 4024NM_203486 10683 ENSG00000090932 DLL3 chr19 42618585 L2c|LINE|L2 18008NM_002698 5452 ENSG00000028277 POU2F2 chr19 42618760 intron (NM_002698,intron 5 of 13) 17833 NM_002698 5452 ENSG00000028277 POU2F2 chr1942618787 MIR3|SINE|MIR 17806 NM_002698 5452 ENSG00000028277 POU2F2 chr1942618789 MIR3|SINE|MIR 17804 NM_002698 5452 ENSG00000028277 POU2F2 chr1942618823 MIR3|SINE|MIR 17770 NM_002698 5452 ENSG00000028277 POU2F2 chr2020232309 exon (NM_015585, exon 20 of 27) −116434 NM_002196 3642ENSG00000173404 INSM1 chr20 20232319 exon (NM_015585, exon 20 of 27)−116424 NM_002196 3642 ENSG00000173404 INSM1 chr20 20232333 exon(NM_015585, exon 20 of 27) −116410 NM_002196 3642 ENSG00000173404 INSM1chr20 20232347 exon (NM_015585, exon 20 of 27) −116396 NM_002196 3642ENSG00000173404 INSM1 chr20 20232348 exon (NM_015585, exon 20 of 27)−116395 NM_002196 3642 ENSG00000173404 INSM1 chr20 20232351 exon(NM_015585, exon 20 of 27) −116392 NM_002196 3642 ENSG00000173404 INSM1chr20 20232352 exon (NM_015585, exon 20 of 27) −116391 NM_002196 3642ENSG00000173404 INSM1 chr20 20232357 exon (NM_015585, exon 20 of 27)−116386 NM_002196 3642 ENSG00000173404 INSM1 chr20 20232358 exon(NM_015585, exon 20 of 27) −116385 NM_002196 3642 ENSG00000173404 INSM1chr20 20232367 exon (NM_015585, exon 20 of 27) −116376 NM_002196 3642ENSG00000173404 INSM1 chr20 20232388 exon (NM_015585, exon 20 of 27)−116355 NM_002196 3642 ENSG00000173404 INSM1 chr20 20266415AluJb|SINE|Alu −82328 NM_002196 3642 ENSG00000173404 INSM1 chr2020376954 intron (NM_020343, intron 39 of 39) 28211 NM_002196 3642ENSG00000173404 INSM1 chr20 20376969 intron (NM_020343, intron 39 of 39)28226 NM_002196 3642 ENSG00000173404 INSM1 chr20 20377086 intron(NM_020343, intron 39 of 39) 28343 NM_002196 3642 ENSG00000173404 INSM1chr20 20377158 intron (NM_020343, intron 39 of 39) 28415 NM_002196 3642ENSG00000173404 INSM1 chr20 20377165 intron (NM_020343, intron 39 of 39)28422 NM_002196 3642 ENSG00000173404 INSM1 chr20 20421292 intron(NM_020343, intron 37 of 39) 72549 NM_002196 3642 ENSG00000173404 INSM1chr20 20421311 intron (NM_020343, intron 37 of 39) 72568 NM_002196 3642ENSG00000173404 INSM1 chr20 20421456 intron (NM_020343, intron 37 of 39)72713 NM_002196 3642 ENSG00000173404 INSM1 chr20 20421483 intron(NM_020343, intron 37 of 39) 72740 NM_002196 3642 ENSG00000173404 INSM1chr20 20433160 CpG 84417 NM_002196 3642 ENSG00000173404 INSM1 chr2020433163 CpG 84420 NM_002196 3642 ENSG00000173404 INSM1 chr20 20433166CpG 84423 NM_002196 3642 ENSG00000173404 INSM1 chr20 20433198 CpG 84455NM_002196 3642 ENSG00000173404 INSM1 chr20 20433208 CpG 84465 NM_0021963642 ENSG00000173404 INSM1 chr20 20433248 CpG 84505 NM_002196 3642ENSG00000173404 INSM1 chr20 20433256 CpG 84513 NM_002196 3642ENSG00000173404 INSM1 chr20 20433263 CpG 84520 NM_002196 3642ENSG00000173404 INSM1 chr20 20433284 CpG 84541 NM_002196 3642ENSG00000173404 INSM1 chr20 20433293 CpG 84550 NM_002196 3642ENSG00000173404 INSM1 chr20 21490704 TTS (NM_002509) 3993 NM_002509 4821ENSG00000125820 NKX2-2 chr20 21490799 TTS (NM_002509) 3898 NM_0025094821 ENSG00000125820 NKX2-2 chr20 21490807 TTS (NM_002509) 3890NM_002509 4821 ENSG00000125820 NKX2-2 chr20 21494139 exon (NM_002509,exon 1 of 2) 558 NM_002509 4821 ENSG00000125820 NKX2-2 chr20 21494141exon (NM_002509, exon 1 of 2) 556 NM_002509 4821 ENSG00000125820 NKX2-2chr20 21494237 exon (NM_002509, exon 1 of 2) 460 NM_002509 4821ENSG00000125820 NKX2-2 chr21 22564429 AluSq2|SINE|Alu 44954 NM_0013525974685 ENSG00000154654 NCAM2 chr21 42850711 MER81|DNA|hAT-Blackjack 29276NM_001135099 7113 ENSG00000184012 TMPRSS2 chr21 42860322 exon(NM_001135099, exon 5 of 14) 19665 NM_001135099 7113 ENSG00000184012TMPRSS2 chr21 42860341 exon (NM_001135099, exon 5 of 14) 19646NM_001135099 7113 ENSG00000184012 TMPRSS2 chr21 42880610 promoter-TSS(NM_001135099) −530 NM_005656 7113 ENSG00000184012 TMPRSS2 chr2142880614 promoter-TSS (NM_001135099) −534 NM_005656 7113 ENSG00000184012TMPRSS2 chr21 42880659 promoter-TSS (NM_001135099) −579 NM_005656 7113ENSG00000184012 TMPRSS2 chr21 42880668 promoter-TSS (NM_001135099) −588NM_005656 7113 ENSG00000184012 TMPRSS2 chr1 3052478 intron (NM_199454,intron 1 of 16) 7944 NR_036215 100422968 ENSG00000283572 MIR4251 chr126735081 Intergenic −9999 NM_024674 79727 ENSG00000131914 LIN28A chr126735241 Intergenic −2062 NM_024674 79727 ENSG00000131914 LIN28A chr126735243 Intergenic −2060 NM_024674 79727 ENSG00000131914 LIN28A chr126735251 Intergenic −2052 NM_024674 79727 ENSG00000131914 LIN28A chr165721361 L2a|LINE|L2 −9011 NM_001256865 9829 ENSG00000116675 DNAJC6 chr1229195756 Intergenic 114787 NR_039659 100616234 ENSG00000283468 MIR4454chr2 23807028 intron (NM_052920, intron 3 of 13) 198983 NM_052920 114818ENSG00000119771 KLHL29 chr2 171679652 CpG-15697 6260 NM_000817 2571ENSG00000128683 GAD1 chr2 236877206 exon (NM_001037131, exon 13 of 18)199818 NM_001301687 2637 ENSG00000168505 GBX2 chr2 242549633 CpG 7278NM_001164356 51078 ENSG00000176946 THAP4 chr2 242549635 CpG 7276NM_001164356 51078 ENSG00000176946 THAP4 chr2 242549638 CpG 7273NM_001164356 51078 ENSG00000176946 THAP4 chr2 242549659 CpG 7252NM_001164356 51078 ENSG00000176946 THAP4 chr3 26664523 promoter-TSS(NM_001317808) 231 NM_052953 116135 ENSG00000179796 LRRC3B chr3126664525 promoter-TSS (NM_001317808) 233 NM_052953 116135ENSG00000179796 LRRC3B chr3 111431556 intron (NM_001185106, intron 2 of4) −19782 NM_001134437 90102 ENSG00000144824 PHLDB2 chr4 169799044 exon(NM_001166110, exon 2 of 12) 45803 NM_001367570 23022 ENSG00000129116PALED chr5 138441347 intron (NM_001037633, intron 4 of 10) 92705NM_022464 64374 ENSG00000120725 SIL1 chr5 138441374 intron(NM_001037633, intron 4 of 10) 92678 NM_022464 64374 ENSG00000120725SIL1 chr5 138441376 intron (NM_001037633, intron 4 of 10) 92676NM_022464 64374 ENSG00000120725 SIL1 chr5 176038510 Intergenic −1358NM_052899 114787 ENSG00000169258 GPRIN1 chr5 176038524 Intergenic −1372NM_052899 114787 ENSG00000169258 GPRIN1 chr5 176038525 Intergenic −1373NM_052899 114787 ENSG00000169258 GPRIN1 chr5 176038562 Intergenic −1410NM_052899 114787 ENSG00000169258 GPRIN1 chr5 179401799 intron(NM_018434, intron 5 of 8) 40593 NR_029885 442908 ENSG00000198995 MIR340chr6 15265454 intron (NM_001267040, intron 1 of 17) 16373 NM_0012670403720 ENSG00000008083 JARID2 chr6 168462402 intron (NR_110312, intron 12of 15) 14108 NM_001122841 79981 ENSG00000153303 FRMD1 chr6 168462447intron (NR_110312, intron 12 of 15) 14063 NM_001122841 79981ENSG00000153303 FRMD1 chr6 170578588 intron (NR_126021, intron 2 of 2)−2969 NR_104177 401289 LINC01624 chr7 2968311 exon (NM_032415, exon 13of 25) −84374 NM_007353 2768 ENSG00000146535 GNA12 chr7 2968441 CpG−84504 NM_007353 2768 ENSG00000146535 GNA12 chr7 2968442 CpG −84505NM_007353 2768 ENSG00000146535 GNA12 chr7 2968451 CpG −84514 NM_0073532768 ENSG00000146535 GNA12 chr7 2968454 CpG −84517 NM_007353 2768ENSG00000146535 GNA12 chr7 5572006 Intergenic −1779 NM_001101 60ENSG00000075624 ACTB chr7 150812220 exon (NM_001308305, exon 1 of 9) 500NM_001308305 116988 ENSG00000133612 AGAP3 chr8 47570600 L1M2|LINE|L1−41340 NR_146077 389652 ENSG00000248498 ASNSP1 chr9 116411412 Intergenic55008 NM_001276262 5998 ENSG00000138835 RGS3 chr9 124498726 CpG −6333NM_138709 153090 ENSG00000136848 DAB2IP chr9 124620057 intron(NM_001139442, intron 8 of 8) 114998 NM_138709 153090 ENSG00000136848DAB2IP chr10 676777 non-coding (NR_147612, exon 2 of 2) 2278 NR_147612101930421 ENSG00000225140 LOC101930421 chr10 676811 non-coding(NR_147612, exon 2 of 2) 2312 NR_147612 101930421 ENSG00000225140LOC101930421 chr11 2000638 Intergenic 10507 NR_024471 100133545ENSG00000226416 MRPL23-AS1 chr11 11600192 intron (NM_001363464, intron 1of 9) 43355 NM_001363464 374378 ENSG00000110328 GALNT18 chr11 11600210intron (NM_001363464, intron 1 of 9) 43337 NM_001363464 374378ENSG00000110328 GALNT18 chr11 11600228 intron (NM_001363464, intron 1 of9) 43319 NM_001363464 374378 ENSG00000110328 GALNT18 chr11 11600230intron (NM_001363464, intron 1 of 9) 43317 NM_001363464 374378ENSG00000110328 GALNT18 chr11 11600231 intron (NM_001363464, intron 1 of9) 43316 NM_001363464 374378 ENSG00000110328 GALNT18 chr11 11600240intron (NM_001363464, intron 1 of 9) 43307 NM_001363464 374378ENSG00000110328 GALNT18 chr11 64120601 exon (NM_032251, exon 21 of 27)−6028 NM_001318361 8986 ENSG00000162302 RPS6KA4 chr11 70851727 intron(NM_012309, intron 2 of 22) 84110 NM_012309 22941 ENSG00000162105 SHANK2chr12 40618451 promoter-TSS (NM_198578) −343 NM_198578 120892ENSG00000188906 LRRK2 chr12 40618493 promoter-TSS (NM_198578) −301NM_198578 120892 ENSG00000188906 LRRK2 chr15 32385689 intron (NM_000746,intron 2 of 9) 62976 NM_000746 1139 ENSG00000175344 CHRNA7 chr1568723747 CpG 750 NM_001004439 22801 ENSG00000137809 ITGA11 chr1589954601 CpG 11204 NR_160724 105371031 LOC105371031 chr15 89954603 CpG11206 NR_160724 105371031 LOC105371031 chr15 89954605 CpG 11208NR_160724 105371031 LOC105371031 chr15 89959942 CpG 16545 NR_160724105371031 LOC105371031 chr16 85498200 MIRb|SINE|MIR −146810 NM_00113447323199 ENSG00000131149 GSE1 chr16 85498219 Intergenic −146791NM_001134473 23199 ENSG00000131149 GSE1 chr16 85498220 Intergenic−146790 NM_001134473 23199 ENSG00000131149 GSE1 chr16 85498227Intergenic −146783 NM_001134473 23199 ENSG00000131149 GSE1 chr1685498781 Intergenic −146229 NM_001134473 23199 ENSG00000131149 GSE1chr16 85519155 CpG −125855 NM_001134473 23199 ENSG00000131149 GSE1 chr1685519162 CpG −125848 NM_001134473 23199 ENSG00000131149 GSE1 chr1685519165 CpG −125845 NM_001134473 23199 ENSG00000131149 GSE1 chr1685519168 CpG −125842 NM_001134473 23199 ENSG00000131149 GSE1 chr1685519171 CpG −125839 NM_001134473 23199 ENSG00000131149 GSE1 chr1685519173 CpG −125837 NM_001134473 23199 ENSG00000131149 GSE1 chr1685519303 CpG −125707 NM_001134473 23199 ENSG00000131149 GSE1 chr1688715953 intron (NM_000101, intron 1 of 5) 1503 NM_000101 1535ENSG00000051523 CYBA chr17 28299568 intron (NR_026738, intron 4 of 15)30921 NM_198529 374786 ENSG00000176927 EFCAB5 chr17 80372745 intron(NR_033265, intron 2 of 9) −3473 NM_001369488 284004 ENSG00000169660HEXD chr17 80372760 intron (NR_033265, intron 2 of 9) −3458 NM_001369488284004 ENSG00000169660 HEXD chr17 80372761 intron (NR_033265, intron 2of 9) −3457 NM_001369488 284004 ENSG00000169660 HEXD chr17 80372766intron (NR_033265, intron 2 of 9) −3452 NM_001369488 284004ENSG00000169660 HEXD chr17 80372767 intron (NR_033265, intron 2 of 9)−3451 NM_001369488 284004 ENSG00000169660 HEXD chr17 80372770 intron(NR_033265, intron 2 of 9) −3448 NM_001369488 284004 ENSG00000169660HEXD chr17 80372771 intron (NR_033265, intron 2 of 9) −3447 NM_001369488284004 ENSG00000169660 HEχD chr17 80372793 intron (NR_033265, intron 2of 9) −3425 NM_001369488 284004 ENSG00000169660 HEXD chr18 57364080CpG-11843 570 NM_133459 147372 ENSG00000183287 CCBE1 chr19 591647 CpG1771 NM_001194 610 ENSG00000099822 HCN2 chr19 591656 CpG 1780 NM_001194610 ENSG00000099822 HCN2 chr19 591660 CpG 1784 NM_001194 610ENSG00000099822 HCN2 chr19 591662 CpG 1786 NM_001194 610 ENSG00000099822HCN2 chr19 591682 CpG 1806 NM_001194 610 ENSG00000099822 HCN2 chr19591683 CpG 1807 NM_001194 610 ENSG00000099822 HCN2 chr19 591684 CpG 1808NM_001194 610 ENSG00000099822 HCN2 chr19 591685 CpG 1809 NM_001194 610ENSG00000099822 HCN2 chr19 591688 CpG 1812 NM_001194 610 ENSG00000099822HCN2 chr19 18837089 intron (NM_001098482, intron 1 of 14) 42604NM_001098482 23373 ENSG00000105662 CRTC1 chr19 18837102 intron(NM_001098482, intron 1 of 14) 42617 NM_001098482 23373 ENSG00000105662CRTC1 chr20 3778162 intron (NM_004358, intron 1 of 15) 1781 NR_136335994 ENSG00000101224 CDC25B chr20 32156432 intron (NM_001039709, intron 1of 10) 6266 NM_005093 9139 ENSG00000078699 CBFA2T2 chr20 48099327promoter-TSS (NM_004975) −127 NM_004975 3745 ENSG00000158445 KCNB1 chr2048099339 promoter-TSS (NM_004975) −139 NM_004975 3745 ENSG00000158445KCNB1 chrX 36981727 CpG −44700 NM_001013736 442444 ENSG00000198173FAM47C chrX 36981729 CpG −44698 NM_001013736 442444 ENSG00000198173FAM47C chr1 24392969 MIRb|SINE|MIR 45556 NM_152372 127294ENSG00000142661 MYOM3 chr1 24410522 MSTA|LTR|ERVL-MaLR 28003 NM_152372127294 ENSG00000142661 MYOM3 chr1 24434829 intron (NM_152372, intron 2of 36) 3696 NM_152372 127294 ENSG00000142661 MYOM3 chr1 24438565promoter-TSS (NM_152372) −40 NM_152372 127294 ENSG00000142661 MYOM3 chr127240357 promoter-TSS (NM_021969) 9 NM_021969 8431 ENSG00000131910 NR0B2chr1 50513586 promoter-TSS (NM_001324208) −41 NM_001324208 1996ENSG00000162374 ELAVL4 chr1 50569482 promoter-TSS (NM_001144776) 1NM_001144776 1996 ENSG00000162374 ELAVL4 chr1 50571262 promoter-TSS(NM_001144775) −541 NM_001144775 1996 ENSG00000162374 ELAVL4 chr150571864 promoter-TSS (NM_001144775) 61 NM_001144775 1996ENSG00000162374 ELAVL4 chr1 50574505 promoter-TSS (NM_001144774) 13NM_021952 1996 ENSG00000162374 ELAVL4 chr1 50574538 promoter-TSS(NM_001144774) 46 NM_021952 1996 ENSG00000162374 ELAVL4 chr1 50575198promoter-TSS (NM_001324217) −207 NM_001324215 1996 ENSG00000162374ELAVL4 chr1 50575278 promoter-TSS (NM_001324217) −127 NM_001324215 1996ENSG00000162374 ELAVL4 chr1 50575388 promoter-TSS (NM_001324217) −17NM_001324215 1996 ENSG00000162374 ELAVL4 chr1 50610525 intron(NR_136725, intron 2 of 4) 35120 NM_001324214 1996 ENSG00000162374ELAVL4 chr1 50642702 exon (NM_001144774, exon 3 of 7) 67297 NM_0013242141996 ENSG00000162374 ELAVL4 chr1 78445126 promoter-TSS (NM_001317099)−337 NM_001303433 8880 ENSG00000162613 FUBP1 chr1 78511486 promoter-TSS(NM_017655) −64 NM_017655 54810 ENSG00000137960 GIPC2 chr1 114521963promoter-TSS (NM_001286353) −33 NM_020190 56944 ENSG00000116774 OLFML3chr1 114521965 promoter-TSS (NM_001286353) −31 NM_020190 56944ENSG00000116774 OLFML3 chr1 114522013 promoter-TSS (NM_001286353) 17NM_001286352 56944 ENSG00000116774 OLFML3 chr1 114522595 exon(NM_001286352, exon 2 of 4) 599 NM_001286352 56944 ENSG00000116774OLFML3 chr1 152956457 promoter-TSS (NM_001199828) 0 NM_001199828 6698ENSG00000169474 SPRR1A chr1 152957607 exon (NM_001199828, exon 2 of 2)1150 NM_005987 6698 ENSG00000169474 SPRR1A chr1 153330230 promoter-TSS(NM_002965) 0 NM_002965 6280 ENSG00000163220 S100A9 chr2 74119341promoter-TSS (NM_001199893) −694 NM_001199893 72 ENSG00000163017 ACTG2chr2 74119978 promoter-TSS (NM_001199893) −57 NM_001199893 72ENSG00000163017 ACTG2 chr2 74119994 promoter-TSS (NM_001199893) −41NM_001199893 72 ENSG00000163017 ACTG2 chr2 74120006 promoter-TSS(NM_001199893) −29 NM_001199893 72 ENSG00000163017 ACTG2 chr2 74120009promoter-TSS (NM_001199893) −26 NM_001199893 72 ENSG00000163017 ACTG2chr2 74120035 promoter-TSS (NM_001199893) 0 NM_001199893 72ENSG00000163017 ACTG2 chr2 95940101 promoter-TSS (NM_001165978) 4NM_001165978 150696 ENSG00000155066 PROM2 chr2 95940121 promoter-TSS(NM_001165978) 24 NM_001165978 150696 ENSG00000155066 PROM2 chr295940140 promoter-TSS (NM_001165978) 43 NM_001165978 150696ENSG00000155066 PROM2 chr2 95940145 promoter-TSS (NM_001165978) 48NM_001165978 150696 ENSG00000155066 PROM2 chr2 95940149 promoter-TSS(NM_001165978) 52 NM_001165978 150696 ENSG00000155066 PROM2 chr295940627 MIR3|SINE|MIR 530 NM_001165978 150696 ENSG00000155066 PROM2chr2 95943464 MIRb|SINE|MIR 3367 NM_001165978 150696 ENSG00000155066PROM2 chr2 95945514 exon (NM_001165978, exon 11 of 24) 5417 NM_001165978150696 ENSG00000155066 PROM2 chr2 95954155 exon (NM_001165978, exon 22of 24) −8840 NM_013434 30818 ENSG00000115041 KCNIP3 chr2 95954163 exon(NM_001165978, exon 22 of 24) −8832 NM_013434 30818 ENSG00000115041KCNIP3 chr2 169921199 L1MC5|LINE|L1 −2288 NM_001289763 10170ENSG00000073737 DHRS9 chr2 169923445 promoter-TSS (NM_001289763) −42NM_001289763 10170 ENSG00000073737 DHRS9 chr2 169923487 promoter-TSS(NM_001289763) 0 NM_001289763 10170 ENSG00000073737 DHRS9 chr2 1699259665′ UTR (NM_199204, exon 2 of 6) 2479 NM_199204 10170 ENSG00000073737DHRS9 chr2 169925972 5′ UTR (NM_199204, exon 2 of 6) 2485 NM_19920410170 ENSG00000073737 DHRS9 chr2 169925986 5′ UTR (NM_199204, exon 2 of6) 2499 NM_199204 10170 ENSG00000073737 DHRS9 chr2 169928910promoter-TSS (NM_001142270) −75 NM_001142270 10170 ENSG00000073737 DHRS9chr2 169937517 promoter-TSS (NM_001142271) 0 NM_001142271 10170ENSG00000073737 DHRS9 chr2 177001240 promoter-TSS (NR_148241) 0NR_148241 401021 LOC401021 chr2 177001585 non-coding (NR_038435, exon 1of 3) 141 NR_038435 100506783 HOXD-AS2 chr2 177015022 promoter-TSS(NR_029609) 91 NR_029609 406903 ENSG00000207744 MIR10B chr2 177025519CpG 3584 NM_006898 3232 ENSG00000128652 HOXD3 chr2 177028705 5′ UTR(NM_006898, exon 2 of 4) 6770 NM_006898 3232 ENSG00000128652 HOXD3 chr2182545174 promoter-TSS (NR_146176) −30 NR_146176 4760 ENSG00000162992NEUROD1 chr2 182545503 promoter-TSS (NR_146176) −211 NR_146175 4760ENSG00000162992 NEUROD1 chr2 219696414 promoter-TSS (NM_017431) 12NM_017431 53632 ENSG00000115592 PRKAG3 chr2 219696424 promoter-TSS(NM_017431) 2 NM_017431 53632 ENSG00000115592 PRKAG3 chr2 219696426promoter-TSS (NM_017431) 0 NM_017431 53632 ENSG00000115592 PRKAG3 chr2219696439 promoter-TSS (NM_017431) −13 NM_017431 53632 ENSG00000115592PRKAG3 chr2 219696709 promoter-TSS (NM_017431) −283 NM_017431 53632ENSG00000115592 PRKAG3 chr2 223916432 promoter-TSS (NM_080671) −116NM_080671 23704 ENSG00000152049 KCNE4 chr2 223916762 5′ UTR (NM_080671,exon 1 of 2) 214 NM_080671 23704 ENSG00000152049 KCNE4 chr2 223916818exon (NM_080671, exon 1 of 2) 270 NM_080671 23704 ENSG00000152049 KCNE4chr2 233924577 promoter-TSS (NM_005541) −375 NM_005541 3635ENSG00000168918 INPP5D chr2 233924962 promoter-TSS (NM_005541) 10NM_001017915 3635 ENSG00000168918 INPP5D chr2 233925089 exon (NM_005541,exon 1 of 26) 137 NM_001017915 3635 ENSG00000168918 INPP5D chr2233940872 intron (NM_001017915, intron 1 of 25) 15920 NM_001017915 3635ENSG00000168918 INPP5D chr2 233985212 intron (NM_001017915, intron 2 of25) 60260 NM_001017915 3635 ENSG00000168918 INPP5D chr2 233986826 exon(NM_005541, exon 3 of 26) 61874 NM_001017915 3635 ENSG00000168918 INPP5Dchr2 234053819 MIRc|SINE|MIR −106298 NM_198890 55054 ENSG00000085978ATG16L1 chr2 234054695 intron (NM_001017915, intron 5 of 25) −105422NM_198890 55054 ENSG00000085978 ATG16L1 chr2 234070270 exon (NM_005541,exon 10 of 26) −89847 NM_198890 55054 ENSG00000085978 ATG16L1 chr2234070335 exon (NM_005541, exon 10 of 26) −89782 NM_198890 55054ENSG00000085978 ATG16L1 chr2 234072847 intron (NM_001017915, intron 11of 25) −87270 NM_198890 55054 ENSG00000085978 ATG16L1 chr2 234078106intron (NM_001017915, intron 13 of 25) −82011 NM_198890 55054ENSG00000085978 ATG16L1 chr2 234078567 intron (NM_001017915, intron 13of 25) −81550 NM_198890 55054 ENSG00000085978 ATG16L1 chr2 234078920intron (NM_001017915, intron 14 of 25) −81197 NM_198890 55054ENSG00000085978 ATG16L1 chr2 234103983 exon (NM_005541, exon 23 of 26)−56134 NM_198890 55054 ENSG00000085978 ATG16L1 chr2 234113188 exon(NM_005541, exon 25 of 26) −46929 NM_198890 55054 ENSG00000085978ATG16L1 chr3 12837871 promoter-TSS (NM_001162499) −208 NM_00116249923066 ENSG00000144712 CAND2 chr3 12838071 promoter-TSS (NM_001162499) −8NM_001162499 23066 ENSG00000144712 CAND2 chr3 12838079 promoter-TSS(NM_001162499) 0 NM_001162499 23066 ENSG00000144712 CAND2 chr3 12848532intron (NM_012298, intron 2 of 12) 10453 NM_012298 23066 ENSG00000144712CAND2 chr3 12868845 exon (NM_001162499, exon 13 of 15) 13004NM_001007074 6161 ENSG00000144713 RPL32 chr3 42726911 promoter-TSS(NM_152393) −18 NM_152393 131377 ENSG00000157119 KLHL40 chr3 111717411promoter-TSS (NM_013259) −75 NM_013259 29114 ENSG00000144834 TAGLN3 chr3111717486 promoter-TSS (NM_013259) 0 NM_013259 29114 ENSG00000144834TAGLN3 chr3 111717542 promoter-TSS (NM_013259) 56 NM_013259 29114ENSG00000144834 TAGLN3 chr3 111717936 promoter-TSS (NM_001008273) 29NM_001008273 29114 ENSG00000144834 TAGLN3 chr3 111718095 5′ UTR(NM_013259, exon 2 of 5) 188 NM_001008273 29114 ENSG00000144834 TAGLN3chr3 111719270 intron (NM_001008273, intron 1 of 3) 1363 NM_00100827329114 ENSG00000144834 TAGLN3 chr3 111719519 exon (NM_013259, exon 3 of5) 1612 NM_001008273 29114 ENSG00000144834 TAGLN3 chr3 128200821 intron(NM_001145661, intron5 of 6) 5843 NM_001145662 2624 ENSG00000179348GATA2 chr3 128206659 promoter-TSS (NM_001145662) 5 NM_001145662 2624ENSG00000179348 GATA2 chr3 128207273 promoter-TSS (NM_001145662) 0NM_001145661 2624 ENSG00000179348 GATA2 chr3 128209391 CpG-18893 1445NR_125398 101927167 GATA2-AS1 chr3 128211916 promoter-TSS (NM_032638) 14NM_032638 2624 ENSG00000179348 GATA2 chr3 128211928 promoter-TSS(NM_032638) 2 NM_032638 2624 ENSG00000179348 GATA2 chr3 150481064promoter-TSS (NM_005067) −208 NM_005067 6478 ENSG00000181788 SIAH2 chr3150481118 promoter-TSS (NM_005067) −262 NM_005067 6478 ENSG00000181788SIAH2 chr3 150481164 promoter-TSS (NM_005067) −308 NM_005067 6478ENSG00000181788 SIAH2 chr3 151154610 TTS (NM_053002) 3858 NM_001178145285313 ENSG00000152580 IGSF10 chr3 151158459 promoter-TSS (NM_001178145)9 NM_001178145 285313 ENSG00000152580 IGSF10 chr3 151158468 promoter-TSS(NM_001178145) 0 NM_001178145 285313 ENSG00000152580 IGSF10 chr3151160838 exon (NM_178822, exon 5 of 6) −2370 NM_001178146 285313ENSG00000152580 IGSF10 chr3 151176397 promoter-TSS (NM_178822) 0NM_178822 285313 ENSG00000152580 IGSF10 chr3 181429614 promoter-TSS(NM_003106) 1 NM_003106 6657 ENSG00000181449 SOX2 chr3 181429622promoter-TSS (NM_003106) 9 NM_003106 6657 ENSG00000181449 SOX2 chr3185782249 intron (NM_004454, intron 8 of 12) 44529 NM_004454 2119ENSG00000244405 ETV5 chr3 185783659 exon (NM_004454, exon 8 of 13) 43119NM_004454 2119 ENSG00000244405 ETV5 chr3 185796794 intron (NM_004454,intron 7 of 12) 29984 NM_004454 2119 ENSG00000244405 ETV5 chr3 185797595exon (NM_004454, exon 7 of 13) 29183 NM_004454 2119 ENSG00000244405 ETV5chr3 185823179 exon (NM_004454, exon 4 of 13) 3599 NM_004454 2119ENSG00000244405 ETV5 chr3 185823413 intron (NM_004454, intron 2 of 12)3365 NM_004454 2119 ENSG00000244405 ETV5 chr3 185823631 5′ UTR(NM_004454, exon 2 of 13) 3147 NM_004454 2119 ENSG00000244405 ETV5 chr3185826233 CpG 545 NM_004454 2119 ENSG00000244405 ETV5 chr3 185826239 CpG539 NM_004454 2119 ENSG00000244405 ETV5 chr3 185826364 CpG 414 NM_0044542119 ENSG00000244405 ETV5 chr3 185826618 CpG 160 NM_004454 2119ENSG00000244405 ETV5 chr3 185826688 promoter-TSS (NM_004454) 90NM_004454 2119 ENSG00000244405 ETV5 chr3 185826770 promoter-TSS(NM_004454) 8 NM_004454 2119 ENSG00000244405 ETV5 chr3 185826801promoter-TSS (NM_004454) −23 NM_004454 2119 ENSG00000244405 ETV5 chr3185828007 Intergenic −1229 NM_004454 2119 ENSG00000244405 ETV5 chr3187086020 promoter-TSS (NM_022147) −53 NM_022147 64108 ENSG00000136514RTP4 chr4 6694696 promoter-TSS (NM_005980) −809 NM_005980 6286ENSG00000163993 S100P chr4 6695505 promoter-TSS (NM_005980) 0 NM_0059806286 ENSG00000163993 S100P chr4 38796154 Intergenic 10158 NM_003263 7096ENSG00000174125 TLR1 chr4 38805897 5′ UTR (NM_003263, exon 2 of 4) 415NM_003263 7096 ENSG00000174125 TLR1 chr4 38806310 promoter-TSS(NM_003263) 2 NM_003263 7096 ENSG00000174125 TLR1 chr4 38806312promoter-TSS (NM_003263) 0 NM_003263 7096 ENSG00000174125 TLR1 chr438806340 promoter-TSS (NM_003263) −28 NM_003263 7096 ENSG00000174125TLR1 chr4 38806372 promoter-TSS (NM_003263) −60 NM_003263 7096ENSG00000174125 TLR1 chr4 38806437 promoter-TSS (NM_003263) −125NM_003263 7096 ENSG00000174125 TLR1 chr4 38807054 promoter-TSS(NM_003263) −742 NM_003263 7096 ENSG00000174125 TLR1 chr4 38807099promoter-TSS (NM_003263) −787 NM_003263 7096 ENSG00000174125 TLR1 chr438858338 promoter-TSS (NM_006068) 0 NM_006068 10333 ENSG00000174130 TLR6chr4 41258330 promoter-TSS (NM_004181) 314 NR_102709 101410542ENSG00000251173 UCHL1-AS1 chr4 41258686 promoter-TSS (NM_004181) −42NR_102709 101410542 ENSG00000251173 UCHL1-AS1 chr4 41258750 promoter-TSS(NM_004181) −95 NM_004181 7345 ENSG00000154277 UCHL1 chr4 41258825promoter-TSS (NM_004181) −20 NM_004181 7345 ENSG00000154277 UCHL1 chr441258828 promoter-TSS (NM_004181) −17 NM_004181 7345 ENSG00000154277UCHL1 chr4 41258849 promoter-TSS (NM_004181) 4 NM_004181 7345ENSG00000154277 UCHL1 chr4 41258850 promoter-TSS (NM_004181) 5 NM_0041817345 ENSG00000154277 UCHL1 chr4 41258857 promoter-TSS (NM_004181) 12NM_004181 7345 ENSG00000154277 UCHL1 chr4 41258862 promoter-TSS(NM_004181) 17 NM_004181 7345 ENSG00000154277 UCHL1 chr4 41258863promoter-TSS (NM_004181) 18 NM_004181 7345 ENSG00000154277 UCHLI chr441262556 intron (NM_004181, intron 3 of 8) 3711 NM_004181 7345ENSG00000154277 UCHL1 chr4 41263656 exon (NM_004181, exon 5 of 9) 4811NM_004181 7345 ENSG00000154277 UCHLI chr4 48899120 intron (NR_104589,intron 2 of 3) 9571 NM_001014446 132299 ENSG00000145247 OCIAD2 chr448899765 exon (NM_001014446, exon 4 of 7) 8926 NM_001014446 132299ENSG00000145247 OCIAD2 chr4 48908644 promoter-TSS (NM_001014446) 47NM_001014446 132299 ENSG00000145247 OCIAD2 chr4 48908674 promoter-TSS(NM_001014446) 17 NM_001014446 132299 ENSG00000145247 OCIAD2 chr448908691 promoter-TSS (NM_001014446) 0 NM_001014446 132299ENSG00000145247 OCIAD2 chr4 48908705 promoter-TSS (NM_001014446) −14NM_001014446 132299 ENSG00000145247 OCIAD2 chr4 48908715 promoter-TSS(NM_001014446) −24 NM_001014446 132299 ENSG00000145247 OCIAD2 chr448908745 promoter-TSS (NM_001014446) 0 NM_152398 132299 ENSG00000145247OCIAD2 chr4 48908854 promoter-TSS (NM_001014446) −109 NM_001286773132299 ENSG00000145247 OC1AD2 chr4 84030896 promoter-TSS (NM_001130716)46 NM_001130716 51316 ENSG00000145287 PLAC8 chr4 84035768 promoter-TSS(NM_016619) 14 NM_016619 51316 ENSG00000145287 PLAC8 chr4 84035789promoter-TSS (NM_016619) −7 NM_001130715 51316 ENSG00000145287 PLAC8chr4 84035855 promoter-TSS (NM_016619) −73 NM_001130715 51316ENSG00000145287 PLAC8 chr4 84058128 Intergenic −22346 NM_001130715 51316ENSG00000145287 PLAC8 chr4 177158625 intron (NM_080874, intron 1 of 6)31648 NM_080874 140458 ENSG00000164122 ASB5 chr4 177162727 intron(NM_080874, intron 1 of 6) 27546 NM_080874 140458 ENSG00000164122 ASB5chr4 177170609 intron (NM_080874, intron 1 of 6) 19664 NM_080874 140458ENSG00000164122 ASB5 chr4 177190273 promoter-TSS (NM_080874) 0 NM_080874140458 ENSG00000164122 ASB5 chr4 177198622 Intergenic −8349 NM_080874140458 ENSG00000164122 ASB5 chr5 102089585 promoter-TSS (NM_001319943)−802 NM_001319943 5066 ENSG00000145730 PAM chr5 102090271 promoter-TSS(NM_001364586) −116 NM_001319943 5066 ENSG00000145730 PAM chr5 102090387promoter-TSS (NM_001364586) 0 NM_001319943 5066 ENSG00000145730 PAM chr5102090918 promoter-TSS (NM_001364586) 9 NR_157231 5066 ENSG00000145730PAM chr5 102090947 promoter-TSS (NM_001364586) 38 NR_157231 5066ENSG00000145730 PAM chr5 102143661 promoter-TSS (NM_001364582) −141NM_001364582 5066 ENSG00000145730 PAM chr5 102143667 promoter-TSS(NM_001364582) −135 NM_001364582 5066 ENSG00000145730 PAM chr5 102200141intron (NM_001364582, intron 1 of 24) −1286 NM_138821 5066ENSG00000145730 PAM chr5 102200848 promoter-TSS (NM_138822) −579NM_138821 5066 ENSG00000145730 PAM chr5 102200914 promoter-TSS(NM_138822) −513 NM_138821 5066 ENSG00000145730 PAM chr5 102201083promoter-TSS (NM_138822) −344 NM_138821 5066 ENSG00000145730 PAM chr5102201330 promoter-TSS (NM_138822) −97 NM_138821 5066 ENSG00000145730PAM chr5 102201341 promoter-TSS (NM_138822) −86 NM_138821 5066ENSG00000145730 PAM chr5 102201423 promoter-TSS (NM_138822) −4 NM_1388215066 ENSG00000145730 PAM chr5 102201427 promoter-TSS (NM_138822) 0NM_138821 5066 ENSG00000145730 PAM chr5 102201614 non-coding (NR_033440,exon 1 of 24) 187 NM_138822 5066 ENSG00000145730 PAM chr5 102201661non-coding (NR_033440, exon 1 of 24) 234 NM_138822 5066 ENSG00000145730PAM chr5 102201720 non-coding (NR_033440, exon 1 of 24) 293 NM_1388225066 ENSG00000145730 PAM chr5 102202191 intron (NM_001364584, intron 2of 25) 764 NM_138822 5066 ENSG00000145730 PAM chr5 102231517 intron(NR_033440, intron 2 of 23) 30090 NM_138822 5066 ENSG00000145730 PAMchr5 102285181 exon (NM_001364582, exon 10 of 25) 83754 NM_138822 5066ENSG00000145730 PAM chr5 102295601 exon (NM_001364582, exon 13 of 25)94174 NM_138822 5066 ENSG00000145730 PAM chr5 102325375 intron(NM_001364591, intron 15 of 24) 123948 NM_138822 5066 ENSG00000145730PAM chr5 102343057 intron (NM_001364584, intron 19 of 25) 112685NM_001317954 54826 ENSG00000145723 GIN1 chr5 102343146 exon(NM_001364582, exon 20 of 25) 112596 NM_001317954 54826 ENSG00000145723GIN1 chr5 102343163 exon (NM_001364582, exon 20 of 25) 112579NM_001317954 54826 ENSG00000145723 GIN1 chr5 102343173 exon(NM_001364582, exon 20 of 25) 112569 NM_001317954 54826 ENSG00000145723GIN1 chr6 34523991 promoter-TSS (NM_001252294) 15 NM_012391 25803ENSG00000124664 SPDEF chr6 34524010 promoter-TSS (NM_001252294) 0NM_001252294 25803 ENSG00000124664 SPDEF chr6 112451090 exon (NM_002290,exon 30 of 39) 42396 NM_001033564 619208 ENSG00000203778 FAM229B chr6112451261 intron (NM_001105206, intron 29 of 38) 42567 NM_001033564619208 ENSG00000203778 FAM229B chr6 112460378 exon (NM_002290, exon 24of 39) 51684 NM_001033564 619208 ENSG00000203778 FAM229B chr6 112486266exon (NM_002290, exon 13 of 39) −71431 NR_121193 101927640 LOC101927640chr6 112500604 intron (NM_001105206, intron 9 of 38) −57093 NR_121193101927640 LOC101927640 chr6 112512866 exon (NM_002290, exon 6 of 39)−44831 NR_121193 101927640 LOC101927640 chr6 112512903 exon (NM_002290,exon 6 of 39) −44794 NR_121193 101927640 LOC101927640 chr6 112512913exon (NM_002290, exon 6 of 39) −44784 NR_121193 101927640 LOC101927640chr6 112537550 exon (NM_002290, exon 3 of 39) −20147 NR_121193 101927640LOC101927640 chr6 112537855 intron (NM_001105206, intron 2 of 38) −19842NR_121193 101927640 LOC101927640 chr6 112575587 promoter-TSS (NM_002290)82 NM_001105207 3910 ENSG00000112769 LAMA4 chr6 112575640 promoter-TSS(NM_002290) 29 NM_001105207 3910 ENSG00000112769 LAMA4 chr6 112575674promoter-TSS (NM_002290) −5 NM_001105206 3910 ENSG00000112769 LAMA4 chr6112575680 promoter-TSS (NM_002290) −11 NM_001105206 3910 ENSG00000112769LAMA4 chr6 112575690 promoter-TSS (NM_002290) −21 NM_001105206 3910ENSG00000112769 LAMA4 chr6 112575702 promoter-TSS (NM_002290) −33NM_001105206 3910 ENSG00000112769 LAMA4 chr6 112575749 promoter-TSS(NM_002290) 68 NM_001105209 3910 ENSG00000112769 LAMA4 chr6 112575812promoter-TSS (NM_002290) 5 NM_001105209 3910 ENSG00000112769 LAMA4 chr6112575817 promoter-TSS (NM_002290) 0 NM_001105209 3910 ENSG00000112769LAMA4 chr6 112575824 promoter-TSS (NM_002290) −7 NM_001105208 3910ENSG00000112769 LAMA4 chr6 112576041 promoter-TSS (NM_002290) −224NM_001105208 3910 ENSG00000112769 LAMA4 chr7 148508815 intron(NM_004456, intron 15 of 19) 71662 NM_001203249 2146 ENSG00000106462EZH2 chr7 148580501 promoter-TSS (NM_001203249) −24 NM_001203249 2146ENSG00000106462 EZH2 chr7 148581151 promoter-TSS (NM_001203249) 132NM_152998 2146 ENSG00000106462 EZH2 chr7 148581237 promoter-TSS(NM_001203247) 46 NM_152998 2146 ENSG00000106462 EZH2 chr7 148581240promoter-TSS (NM_001203247) 43 NM_152998 2146 ENSG00000106462 EZH2 chr7148581270 promoter-TSS (NM_001203247) 13 NM_152998 2146 ENSG00000106462EZH2 chr7 148581275 promoter-TSS (NM_001203247) 8 NM_152998 2146ENSG00000106462 EZH2 chr7 148581279 promoter-TSS (NM_001203247) 4NM_152998 2146 ENSG00000106462 EZH2 chr7 148581313 promoter-TSS(NM_001203247) 28 NM_004456 2146 ENSG00000106462 EZH2 chr8 17169082intron (NM_004686, intron 8 of 13) 64715 NM_152415 137492ENSG00000155975 VPS37A chr8 17169272 intron (NM_004686, intron 8 of 13)64905 NM_152415 137492 ENSG00000155975 VPS37A chr8 17206466 exon(NM_004686, exon 5 of 14) 64294 NM_004686 9108 ENSG00000003987 MTMR7chr8 17206646 intron (NM_004686, intron 4 of 13) 64114 NM_004686 9108ENSG00000003987 MTMR7 chr8 17206894 L2c|LINE|L2 63866 NM_004686 9108ENSG00000003987 MTMR7 chr8 17270716 promoter-TSS (NM_004686) 44NM_004686 9108 ENSG00000003987 MTMR7 chr8 17270736 promoter-TSS(NM_004686) 24 NM_004686 9108 ENSG00000003987 MTMR7 chr8 17270937promoter-TSS (NM_004686) −177 NM_004686 9108 ENSG00000003987 MTMR7 chr853045604 intron (NM_001352827, intron 21 of 26) −61218 NR_134310101929341 ENSG00000253551 LOC101929341 chr8 53045678 intron(NM_001352827, intron 21 of 26) −61144 NR_134310 101929341ENSG00000253551 LOC101929341 chr8 53050272 intron (NM_001352827, intron18 of 26) −56550 NR_134310 101929341 ENSG00000253551 LOC101929341 chr853130239 5′ UTR (NM_001352857, exon 6 of 26) 23417 NR_134310 101929341ENSG00000253551 LOC101929341 chr8 5313028 5′ UTR (NM_001352857, exon 6of 26) 23459 NR_134310 101929341 ENSG00000253551 LOC101929341 chr853130282 5′ UTR (NM_001352857, exon 6 of 26) 23460 NR_134310 101929341ENSG00000253551 LOC101929341 chr8 53134555 intron (NM_001352838, intron2 of 23) 26549 NM_001352869 9705 ENSG00000147488 ST18 chr8 53159124non-coding (NR_148195, exon 3 of 4) 1980 NM_001352869 9705ENSG00000147488 ST18 chr8 53160986 non-coding (NR_148196, exon 1 of 2)118 NM_001352869 9705 ENSG00000147488 ST18 chr8 53161872 promoter-TSS(NM_001352856) 85 NM_001352854 9705 ENSG00000147488 ST18 chr8 531668085′ UTR (NM_001352839, exon 1 of 23) 144 NM_001352859 9705ENSG00000147488 ST18 chr8 53322203 promoter-TSS (NM_001352883) 13NM_001352884 9705 ENSG00000147488 ST18 chr8 53322209 promoter-TSS(NM_001352883) 7 NM_001352884 9705 ENSG00000147488 ST18 chr8 53322216promoter-TSS (NM_001352883) 0 NM_001352884 9705 ENSG00000147488 ST18chr8 53322232 promoter-TSS (NM_001352883) −16 NM_001352883 9705ENSG00000147488 ST18 chr8 53322252 promoter-TSS (NM_001352826) −36NM_001352883 9705 ENSG00000147488 ST18 chr8 53322265 promoter-TSS(NM_001352826) −49 NM_001352883 9705 ENSG00000147488 ST18 chr8 53322339promoter-TSS (NM_001352826) 0 NM_001352880 9705 ENSG00000147488 ST18chr8 53322342 promoter-TSS (NM_001352826) −3 NM_001352831 9705ENSG00000147488 ST18 chr8 53322405 promoter-TSS (NM_001352826) −66NM_001352831 9705 ENSG00000147488 ST18 chr8 53373419 Intergenic −51080NM_001352831 9705 ENSG00000147488 ST18 chr8 104152838 promoter-TSS(NM_001024372) −15 NM_001364874 79870 ENSG00000164929 BAALC chr8104152841 promoter-TSS (NM_001024372) −12 NM_001364874 79870ENSG00000164929 BAALC chr8 104152887 promoter-TSS (NM_001024372) 34NM_024812 79870 ENSG00000164929 BAALC chr8 104153026 TTS (NR_145429) 173NM_024812 79870 ENSG00000164929 BAALC chr8 104165267 intron(NM_001024372, intron 1 of 1) −1475 NR_036106 100422992 ENSG00000265657MIR3151 chr8 104220320 intron (NM_001364874, intron 2 of 3) −36052NR_109954 100499183 ENSG00000247081 BAALC-AS1 chr8 104225459 intron(NM_001364874, intron 3 of 3) −41191 NR_109954 100499183 ENSG00000247081BAALC-AS1 chr8 104225539 intron (NM_001364874, intron 3 of 3) −41271NR_109954 100499183 ENSG00000247081 BAALC-AS1 chr10 69597717 5′ UTR(NM_021800, exon 1 of 5) 120 NM_201262 56521 ENSG00000108176 DNAJC12chr10 69597721 5′ UTR (NM_021800, exon 1 of 5) 116 NM_201262 56521ENSG00000108176 DNAJC12 chr10 69597754 promoter-TSS (NM_021800) 83NM_201262 56521 ENSG00000108176 DNAJC12 chr10 69597822 promoter-TSS(NM_021800) 15 NM_201262 56521 ENSG00000108176 DNAJC12 chr10 69597824promoter-TSS (NM_021800) 13 NM_201262 56521 ENSG00000108176 DNAJC12chr10 88428106 promoter-TSS (NM_001080116) −62 NM_001171610 11155ENSG00000122367 LDB3 chr10 88428270 promoter-TSS (NM_001080116) 49NM_001080116 11155 ENSG00000122367 LDB3 chr10 88428326 5′ UTR(NM_001080116, exon 1 of 8) 105 NM_001080116 11155 ENSG00000122367 LDB3chr10 88428328 5′ UTR (NM_001080116, exon 1 of 8) 107 NM_001080116 11155ENSG00000122367 LDB3 chr10 88428349 exon (NM_001080116, exon 1 of 8) 128NM_001080116 11155 ENSG00000122367 LDB3 chr10 88478387 exon (NM_007078,exon 12 of 14) −37909 NM_004329 657 ENSG00000107779 BMPR1A chr1092680933 promoter-TSS (NM_014391) −1 NM_014391 27063 ENSG00000148677ANKRD1 chr11 60869767 promoter-TSS (NM_014207) −94 NM_014207 921ENSG00000110448 CD5 chr11 60869881 promoter-TSS (NM_014207) 20 NM_014207921 ENSG00000110448 CD5 chr11 67350966 promoter-TSS (NM_000852) 0NM_000852 2950 ENSG00000084207 GSTP1 chr11 67351113 5′ UTR (NM_000852,exon 1 of 7) 147 NM_000852 2950 ENSG00000084207 GSTP1 chr11 67351193 5′UTR (NM_000852, exon 1 of 7) 227 NM_000852 2950 ENSG00000084207 GSTP1chr11 67351495 CpG 529 NM_000852 2950 ENSG00000084207 GSTP1 chr1167351496 CpG 530 NM_000852 2950 ENSG00000084207 GSTP1 chr11 67351505exon (NM_000852, exon 2 of 7) 539 NM_000852 2950 ENSG00000084207 GSTP1chr11 67351826 CpG-4453 860 NM_000852 2950 ENSG00000084207 GSTP1 chr1167352166 intron (NM_000852, intron 4 of 6) 1200 NM_000852 2950ENSG00000084207 GSTP1 chr11 67353475 exon (NM_000852, exon 6 of 7) 2509NM_000852 2950 ENSG00000084207 GSTP1 chr11 87908501 promoter-TSS(NM_022337) 10 NM_022337 23682 ENSG00000123892 RAB38 chr11 87908502promoter-TSS (NM_022337) 9 NM_022337 23682 ENSG00000123892 RAB38 chr1187908535 promoter-TSS (NM_022337) −24 NM_022337 23682 ENSG00000123892RAB38 chr11 112831897 promoter-TSS (NM_001242608) −145 NM_001242608 4684ENSG00000149294 NCAM1 chr11 112831990 promoter-TSS (NM_001242608) −52NM_001242608 4684 ENSG00000149294 NCAM1 chr11 112832024 promoter-TSS(NM_001242608) −18 NM_001242608 4684 ENSG00000149294 NCAM1 chr11112832047 promoter-TSS (NM_001242608) 5 NM_001076682 4684ENSG00000149294 NCAM1 chr11 112832057 promoter-TSS (NM_001242608) 15NM_001076682 4684 ENSG00000149294 NCAM1 chr11 112832058 promoter-TSS(NM_001242608) 16 NM_001076682 4684 ENSG00000149294 NCAM1 chr11112832059 promoter-TSS (NM_001242608) 17 NM_001076682 4684ENSG00000149294 NCAM1 chr11 112832061 promoter-TSS (NM_001242608) 19NM_001076682 4684 ENSG00000149294 NCAM1 chr11 112832102 promoter-TSS(NM_001242608) 60 NM_001076682 4684 ENSG00000149294 NCAM1 chr11113001316 intron (NM_181351, intron 2 of 19) 143207 NR_034101 100288346ENSG00000227487 NCAM1-AS1 chr11 113003550 intron (NM_181351, intron 2 of19) 140973 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11 113067815THE1C|LTR|ERVL-MaLR 76708 NR_034101 100288346 ENSG00000227487 NCAM1-AS1chr11 113072979 (TTTTG)n|Simple_repeat|Simple_repeat 71544 NR_034101100288346 ENSG00000227487 NCAM1-AS1 chr11 113072998 intron (NM_181351,intron 2 of 19) 71525 NR_034101 100288346 ENSG00000227487 NCAM1-AS1chr11 113102002 intron (NM_001242607, intron 11 of 20) 42521 NR_034101100288346 ENSG00000227487 NCAM1-AS1 chr11 113102884 exonfNM_001242608,exon 11 of 17) 41639 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11113102947 exon (NM_001242608, exon 11 of 17) 41576 NR_034101 100288346ENSG00000227487 NCAM1-AS1 chr11 113103415 exon (NM_001242608, exon 12 of17) 41108 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11 113103417exon (NM_001242608, exon 12 of 17) 41106 NR_034101 100288346ENSG00000227487 NCAM1-AS1 chr11 113103766 intron (NM_181351, intron 13of 19) 40757 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11113103880 exon (NM_001242608, exon 13 of 17) 40643 NR_034101 100288346ENSG00000227487 NCAM1-AS1 chr11 113111129 intron (NM_001076682, intron15 of 19) 33394 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11113116730 intron (NM_001076682, intron 17 of 19) 27793 NR_034101100288346 ENSG00000227487 NCAM1-AS1 chr11 113126572 exon (NM_001242608,exon 15 of 17) 17951 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11113130713 intron (NM_181351, intron 16 of 19) 13810 NR_034101 100288346ENSG00000227487 NCAM1-AS1 chr11 113130880 exon (NM_001242608, exon 16 of17) 13643 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11 113140591intron (NR_034101, intron 2 of 2) 3932 NR_034101 100288346ENSG00000227487 NCAM1-AS1 chr11 113143642 intron (NM_181351, intron 19of 19) 881 NR_034101 100288346 ENSG00000227487 NCAM1-AS1 chr11 133938720promoter-TSS (NM_001205329) 0 NM_001205329 83700 ENSG00000166086 JAM3chr11 133938866 promoter-TSS (NM_032801) −1 NM_032801 83700ENSG00000166086 JAM3 chr11 133938880 promoter-TSS (NM_032801) 13NM_032801 83700 ENSG00000166086 JAM3 chr11 133996134 intron (NM_032801,intron 1 of 8) 25024 NR_145790 109623486 SNORD153 chr11 134009435 intron(NM_032801, intron 1 of 8) 11723 NR_145790 109623486 SNORD153 chr11134017593 intron (NM_032801, intron 6 of 8) 3565 NR_145790 109623486SNORD153 chr11 7022809 promoter-TSS (NM_001975) −835 NM_001975 2026ENSG00000111674 ENO2 chr11 7023391 promoter-TSS (NM_001975) −253NM_001975 2026 ENSG00000111674 ENO2 chr11 7023514 promoter-TSS(NM_001975) −130 NM_001975 2026 ENSG00000111674 ENO2 chr11 7023602promoter-TSS (NM_001975) −42 NM_001975 2026 ENSG00000111674 ENO2 chr117023621 promoter-TSS (NM_001975) −23 NM_001975 2026 ENSG00000111674 ENO2chr12 7023653 promoter-TSS (NM_001975) 9 NM_001975 2026 ENSG00000111674ENO2 chr12 7023658 promoter-TSS (NM_001975) 14 NM_001975 2026ENSG00000111674 ENO2 chr12 7023661 promoter-TSS (NM_001975) 17 NM_0019752026 ENSG00000111674 ENO2 chr12 7023674 promoter-TSS (NM_001975) 30NM_001975 2026 ENSG00000111674 ENO2 chr12 7024271 TTS (NM_001135217) 627NM_001975 2026 ENSG00000111674 ENO2 chr12 7026393 intron (NM_001975,intron 5 of 11) 2749 NM_001975 2026 ENSG00000111674 ENO2 chr11 7028638exon (NM_001975, exon 8 of 12) −4884 NM_001007026 1822 ENSG00000111676ATN1 chr11 7030644 exon (NM_001975, exon 9 of 12) −2878 NM_0010070261822 ENSG00000111676 ATN1 chr11 7031052 intron (NM_001975, intron 9 of11) −2470 NM_001007026 1822 ENSG00000111676 ATN1 chr11 24983162 intron(NM_001178092, intron 7 of 8) 71894 NM_001178094 586 ENSG00000060982BCAT1 chr12 25055130 promoter-TSS (NM_001178094) −74 NM_001178094 586ENSG00000060982 BCAT1 chr12 25055222 promoter-TSS (NM_001178094) −166NM_001178094 586 ENSG00000060982 BCAT1 chr12 25055909 promoter-TSS(NM_001178094) −8 NM_001178093 586 ENSG00000060982 BCAT1 chr12 25101877promoter-TSS (NM_001178091) 58 NM_001178092 586 ENSG00000060982 BCAT1chr12 25101883 promoter-TSS (NM_001178091) 52 NM_001178092 586ENSG00000060982 BCAT1 chr11 25101895 promoter-TSS (NM_001178091) 40NM_001178092 586 ENSG00000060982 BCAT1 chr11 25101920 promoter-TSS(NM_001178091) 15 NM_001178092 586 ENSG00000060982 BCAT1 chr12 25102293promoter-TSS (NM_001178091) −358 NM_001178091 586 ENSG00000060982 BCAT1chr12 25173836 intron (NM_001321724, intron 8 of 17) 23427 NM_001321724645177 LOC645177 chr12 25186593 intron (NM_001321724, intron 13 of 17)−18469 NM_001366542 4033 ENSG00000118308 LRMP chr12 25188314 intron(NM_001321724, intron 14 of 17) −16748 NM_001366542 4033 ENSG00000118308LRMP chr12 25205089 promoter-TSS (NM_001366542) 27 NR_159366 4033ENSG00000118308 LRMP chr12 25205105 promoter-TSS (NM_001366542) 43NR_159366 4033 ENSG00000118308 LRMP chr12 25205106 promoter-TSS(NM_001366542) 44 NR_159366 4033 ENSG00000118308 LRMP chr12 25205346promoter-TSS (NM_001204126) −194 NM_001204126 4033 ENSG00000118308 LRMPchr11 25205421 promoter-TSS (NM_001204126) −119 NM_001204126 4033ENSG00000118308 LRMP chr11 25205476 promoter-TSS (NM_001204126) −64NM_001204126 4033 ENSG00000118308 LRMP chr12 25205499 promoter-TSS(NM_001204126) −41 NM_001204126 4033 ENSG00000118308 LRMP chr11 25205534promoter-TSS (NM_001204126) −6 NM_001204126 4033 ENSG00000118308 LRMPchr12 25205574 promoter-TSS (NM_001204126) 34 NM_001204127 4033ENSG00000118308 LRMP chr12 25205779 TTS (NM_001321724) 239 NM_0012041274033 ENSG00000118308 LRMP chr12 25228574 intron (NR_159367, intron 5 of19) 23034 NM_001204127 4033 ENSG00000118308 LRMP chr11 25242608 exon(NM_001366542, exon 12 of 21) 37068 NM_001204127 4033 ENSG00000118308LRMP chr11 25249767 exon (NM_001366542, exon 14 of 21) 44227NM_001204127 4033 ENSG00000118308 LRMP chr12 25249792 exon(NM_001366542, exon 14 of 21) 44252 NM_001204127 4033 ENSG00000118308LRMP chr12 25257163 intron (NR_159367, intron 18 of 19) 51623NM_001204127 4033 ENSG00000118308 LRMP chr12 66582559 promoter-TSS(NM_001142523) −335 NM_007199 11213 ENSG00000090376 IRAK3 chr12 66582875promoter-TSS (NM_001142523) −19 NM_007199 11213 ENSG00000090376 IRAK3chr11 66582937 promoter-TSS (NM_001142523) 43 NM_001142523 11213ENSG00000090376 IRAK3 chr12 70082891 promoter-TSS (NM_152439) 66NR_104220 144453 ENSG00000127325 BEST3 chr12 70082956 promoter-TSS(NM_152439) 1 NR_104220 144453 ENSG00000127325 BEST3 chr12 70087752intron (NM_001282615, intron 1 of 2) −4795 NM_152439 144453ENSG00000127325 BEST3 chr12 70092965 promoter-TSS (NM_0012X2616) 18NM_032735 144453 ENSG00000127325 BEST3 chr12 70093015 promoter-TSS(NM_001282614) −32 NM_001282615 144453 ENSG00000127325 BEST3 chr1270093024 promoter-TSS (NM_001282614) −41 NM_001282615 144453ENSG00000127325 BEST3 chr11 70093031 promoter-TSS (NM_001282614) −48NM_001282615 144453 ENSG00000127325 BEST3 chr11 70093041 promoter-TSS(NM_001282614) 55 NM_001282613 144453 ENSG00000127325 BEST3 chr1270093044 promoter-TSS (NM_001282614) 52 NM_001282613 144453ENSG00000127325 BEST3 chr12 70093075 promoter-TSS (NM_001282614) 21NM_001282613 144453 ENSG00000127325 BEST3 chr12 70093096 promoter-TSS(NM_001282614) 0 NM_001282613 144453 ENSG00000127325 BEST3 chr1270093156 promoter-TSS (NM_001282614) −60 NM_001282614 144453ENSG00000127325 BEST3 chr12 103351364 promoter-TSS (NM_004316) 12NM_004316 429 ENSG00000139352 ASCL1 chr13 102527544 exon (NM_001321933,exon 3 of 6) 41351 NM_004115 2259 ENSG00000102466 FGF14 chr13 102568895promoter-TSS (NM_004115) 0 NM_004115 2259 ENSG00000102466 FGF14 chr13103054024 promoter-TSS (NM_175929) 0 NM_175929 2259 ENSG00000102466FGF14 chr14 21994247 non-coding (NR_111967, exon 1 of 3) 133NM_001364564 6297 ENSG00000165821 SALL2 chr14 21994261 non-coding(NR_111967, exon 1 of 3) 119 NM_001364564 6297 ENSG00000165821 SALL2chr14 21994534 promoter-TSS (NR_111967) −92 NR_111967 6297ENSG00000165821 SALL2 chr14 22004936 non-coding (NR_111966, exon 1 of 3)219 NM_001291446 6297 ENSG00000165821 SALL2 chr14 22004968 non-coding(NR_111966, exon 1 of 3) 187 NM_001291446 6297 ENSG00000165821 SALL2chr14 22005138 promoter-TSS (NM_001291446) 17 NM_001291446 6297ENSG00000165821 SALL2 chr14 22005250 promoter-TSS (NR_111966) 0NR_111966 6297 ENSG00000165821 SALL2 chr14 51448929 intron (NM_015163,intron 7 of 9) −37828 NM_001163940 5836 ENSG00000100504 PYGL chr1451453070 intron (NM_015163, intron 7 of 9) −41969 NM_001163940 5836ENSG00000100504 PYGL chr14 51454994 intron (NM_015163, intron 7 of 9)−43893 NM_001163940 5836 ENSG00000100504 PYGL chr14 51561694 5′ UTR(NM_015163, exon 1 of 10) 628 NM_015163 114088 ENSG00000100505 TRIM9chr14 51561947 5′ UTR (NM_015163, exon 1 of 10) 375 NM_015163 114088ENSG00000100505 TRIM9 chr14 51562679 promoter-TSS (NM_015163) −357NM_052978 114088 ENSG00000100505 TRIM9 chr14 75988668 promoter-TSS(NM_006399) −44 NM_006399 10538 ENSG00000156127 BATF chr14 75988698promoter-TSS (NM_006399) −14 NM_006399 10538 ENSG00000156127 BATF chr1475988803 promoter-TSS (NM_006399) 91 NM_006399 10538 ENSG00000156127BATF chr14 93389325 promoter-TSS (NM_001275) −70 NM_001301690 1113ENSG00000100604 CHGA chr14 93389402 promoter-TSS (NM_001275) 7 NM_0012751113 ENSG00000100604 CHGA chr14 93389421 promoter-TSS (NM_001275) 26NM_001275 1113 ENSG00000100604 CHGA chr14 93389608 exon (NM_001275, exon1 of 8) 213 NM_001275 1113 ENSG00000100604 CHGA chr14 93392346 intron(NM_001301690, intron 2 of 6) 2951 NM_001275 1113 ENSG00000100604 CHGAchr14 93397922 exon (NM_001275, exon 6 of 8) 8527 NM_001275 1113ENSG00000100604 CHGA chr15 74465912 promoter-TSS (NM_005545) −39NM_005545 3671 ENSG00000129009 ISLR chr15 74466371 promoter-TSS(NM_201526) −417 NM_201526 3671 ENSG00000129009 ISLR chr15 74466644promoter-TSS (NM_201526) −144 NM_201526 3671 ENSG00000129009 ISLR chr1574466742 promoter-TSS (NM_201526) −46 NM_201526 3671 ENSG00000129009ISLR chr15 77285600 Intergenic −1321 NM_001321137 9051 ENSG00000140368PSTPIP1 chr15 77286921 promoter-TSS (NM_001321136) 0 NM_001321137 9051ENSG00000140368 PSTPIP1 chr15 77287326 promoter-TSS (NM_001321136) −41NM_001321136 9051 ENSG00000140368 PSTPIP1 chr15 77287363 promoter-TSS(NM_001321136) −4 NM_001321136 9051 ENSG00000140368 PSTPIP1 chr1577287365 promoter-TSS (NM_001321136) −2 NM_001321136 9051ENSG00000140368 PSTPIP1 chr15 77287367 promoter-TSS (NM_001321136) 0NM_001321136 9051 ENSG00000140368 PSTPIP1 chr15 77287372 promoter-TSS(NM_001321136) 5 NR_135552 9051 ENSG00000140368 PSTPIP1 chr15 77287413promoter-TSS (NM_001321136) 46 NR_135552 9051 ENSG00000140368 PSTPIP1chr15 77287603 non-coding (NR_135552, exon 1 of 12) 236 NR_135552 9051ENSG00000140368 PSTPIP1 chr15 77287626 non-coding (NR_135552, exon 1 of12) 259 NR_135552 9051 ENSG00000140368 PSTPIP1 chr15 77287653 exon(NM_001321137, exon 2 of 16) 286 NR_135552 9051 ENSG00000140368 PSTPIP1chr15 77287660 exon (NM_001321137, exon 2 of 16) 293 NR_135552 9051ENSG00000140368 PSTPIP1 chr15 77287815 exon (NM_001321135, exon 1 of 14)448 NR_135552 9051 ENSG00000140368 PSTPIP1 chr15 77308052 intron(NM_001321136, intron 2 of 15) 20685 NR_135552 9051 ENSG00000140368PSTPIP1 chr15 77310699 exon (NM_001321136, exon 4 of 16) 23332 NR_1355529051 ENSG00000140368 PSTPIP1 chr15 77319966 intron (NR_135552, intron 5of 11) 32599 NR_135552 9051 ENSG00000140368 PSTPIP1 chr15 77320584intron (NR_135552, intron 6 of 11) 33217 NR_135552 9051 ENSG00000140368PSTPIP1 chr15 77324558 exon (NM_001321136, exon 12 of 16) 37191NR_135552 9051 ENSG00000140368 PSTPIP1 chr15 77327935 intron (NR_135552,intron 10 of 11) 35416 NM_001168412 10099 ENSG00000140391 TSPAN3 chr1629674500 promoter-TSS (NM_003123) 32 NM_003123 6693 ENSG00000197471 SPNchr16 29690229 promoter-TSS (NR_134536) 0 NM_001318250 23475ENSG00000103485 QPRT chr16 29690258 promoter-TSS (NR_134536) 29NM_001318249 23475 ENSG00000103485 QPRT chr16 29690403 promoter-TSS(NR_134536) 2 NR_134536 23475 ENSG00000103485 QPRT chr16 29707018 intron(NM_014298, intron 2 of 3) 16617 NR_134536 23475 ENSG00000103485 QPRTchr16 31146861 promoter-TSS (NM_002773) 87 NM_002773 5652ENSG00000052344 PRSS8 chr16 31146924 promoter-TSS (NM_002773) 24NM_002773 5652 ENSG00000052344 PRSS8 chr16 31146948 promoter-TSS(NM_002773) 0 NM_002773 5652 ENSG00000052344 PRSS8 chr16 31146983promoter-TSS (NM_002773) −35 NM_002773 5652 ENSG00000052344 PRSS8 chr1674710849 AluY|SINE|Alu −10174 NM_001370536 55159 ENSG00000168411 RFWD3chr16 74712211 intron (NM_152649, intron 7 of 10) −11536 NM_00137053655159 ENSG00000168411 RFWD3 chr16 74712746 exon (NM_152649, exon 7 of11) −12071 NM_001370536 55159 ENSG00000168411 RFWD3 chr16 74725267intron (NM_152649, intron 3 of 10) 9393 NM_152649 197259 ENSG00000168404MLKL chr16 74734588 promoter-TSS (NM_001142497) 72 NM_152649 197259ENSG00000168404 MLKL chr16 74734607 promoter-TSS (NM_001142497) 53NM_152649 197259 ENSG00000168404 MLKL chr16 74734712 promoter-TSS(NM_001142497) −52 NM_001142497 197259 ENSG00000168404 MLKL chr1674734758 promoter-TSS (NM_001142497) −98 NM_001142497 197259ENSG00000168404 MLKL chr16 88713133 exon (NM_000101, exon 4 of 6) 4228NM_000101 1535 ENSG00000051523 CYBA chr16 88716622 intron (NM_000101,intron 1 of 5) 739 NM_000101 1535 ENSG00000051523 CYBA chr16 88717296promoter-TSS (NM_000101) 65 NM_000101 1535 ENSG00000051523 CYBA chr1688717323 promoter-TSS (NM_000101) 38 NM_000101 1535 ENSG00000051523 CYBAchr16 88717338 promoter-TSS (NM_000101) 23 NM_000101 1535ENSG00000051523 CYBA chr16 88717339 promoter-TSS (NM_000101) 22NM_000101 1535 ENSG00000051523 CYBA chr16 88717343 promoter-TSS(NM_000101) 18 NM_000101 1535 ENSG00000051523 CYBA chr16 88717349promoter-TSS (NM_000101) 12 NM_000101 1535 ENSG00000051523 CYBA chr1688717362 promoter-TSS (NM_000101) −1 NM_000101 1535 ENSG00000051523 CYBAchr16 88717460 promoter-TSS (NM_000101) −99 NM_000101 1535ENSG00000051523 CYBA chr17 1665153 promoter-TSS (NM_002615) 34NM_001329904 5176 ENSG00000132386 SERPINF1 chr17 1665223 promoter-TSS(NM_002615) −31 NM_002615 5176 ENSG00000132386 SERPINF1 chr17 1665255promoter-TSS (NM_002615) 1 NM_002615 5176 ENSG00000132386 SERPINF1 chr171665262 promoter-TSS (NM_002615) 8 NM_002615 5176 ENSG00000132386SERPINF1 chr17 1665306 promoter-TSS (NM_002615) 52 NM_002615 5176ENSG00000132386 SERPINF1 chr17 1666023 promoter-TSS (NM_001329903) 25NM_001329903 5176 ENSG00000132386 SERPINF1 chr17 1669468 AluSx1|SINE|Alu3470 NM_001329903 5176 ENSG00000132386 SERPINF1 chr17 1673720AluSx1|SINE|Alu −1145 NM_001329905 5176 ENSG00000132386 SERPINF1 chr171674913 promoter-TSS (NM_001329905) 48 NM_001329905 5176 ENSG00000132386SERPINF1 chr17 1679644 intron (NM_001329903, intron 6 of 7) 4779NM_001329905 5176 ENSG00000132386 SERPINF1 chr17 27283357 exon(NM_178860, exon 15 of 17) −4921 NM_020889 57649 ENSG00000109118 PHF12chr17 27284731 MIR|SINE|MIR −6295 NM_020889 57649 ENSG00000109118 PHF12chr17 27287891 exon (NM_178860, exon 6 of 17) −9455 NM_020889 57649ENSG00000109118 PHF12 chr17 27308510 exon (NM_178860, exon 2 of 17)24441 NM_001098635 124925 ENSG00000063015 SEZ6 chr17 27308790 exon(NM_178860, exon 2 of 17) 24161 NM_001098635 124925 ENSG00000063015 SEZ6chr17 27332831 5′ UTR (NM_178860, exon 1 of 17) 120 NM_001098635 124925ENSG00000063015 SEZ6 chr17 27332981 promoter-TSS (NM_178860) −30NM_178860 124925 ENSG00000063015 SEZ6 chr17 27333063 promoter-TSS(NM_178860) −112 NM_178860 124925 ENSG00000063015 SEZ6 chr17 27333216promoter-TSS (NM_178860) 142 NM_001290202 124925 ENSG00000063015 SEZ6chr17 27333358 promoter-TSS (NM_178860) 0 NM_001290202 124925ENSG00000063015 SEZ6 chr17 62007774 intron (NM_001039933, intron 2 of 5)1817 NM_000626 974 ENSG00000007312 CD79B chr17 62009521 promoter-TSS(NM_000626) 70 NM_000626 974 ENSG00000007312 CD79B chr17 62009583promoter-TSS (NM_000626) 8 NM_000626 974 ENSG00000007312 CD79B chr1762009591 promoter-TSS (NM_000626) 0 NM_000626 974 ENSG00000007312 CD79Bchr17 62009596 promoter-TSS (NM_000626) −5 NM_001039933 974ENSG00000007312 CD79B chr17 62009614 promoter-TSS (NM_000626) −23NM_001039933 974 ENSG00000007312 CD79B chr17 76970778 exon (NM_005567,exon 4 of 6) 5127 NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76970979intron (NM_005567, intron 3 of 5) 4926 NM_005567 3959 ENSG00000108679LGALS3BP chr17 76972138 exon (NM_005567, exon 3 of 6) 3767 NM_0055673959 ENSG00000108679 LGALS3BP chr17 76973198 intron (NM_005567, intron 1of 5) 2707 NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76973305 intron(NM_005567, intron 1 of 5) 2600 NM_005567 3959 ENSG00000108679 LGALS3BPchr17 76975825 promoter-TSS (NM_005567) 80 NM_005567 3959ENSG00000108679 LGALS3BP chr17 76975857 promoter-TSS (NM_005567) 48NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76975873 promoter-TSS(NM_005567) 32 NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76975890promoter-TSS (NM_005567) 15 NM_005567 3959 ENSG00000108679 LGALS3BPchr17 76975893 promoter-TSS (NM_005567) 12 NM_005567 3959ENSG00000108679 LGALS3BP chr17 76975900 promoter-TSS (NM_005567) 5NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76975905 promoter-TSS(NM_005567) 0 NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76975909promoter-TSS (NM_005567) −4 NM_005567 3959 ENSG00000108679 LGALS3BPchr17 76975917 promoter-TSS (NM_005567) −12 NM_005567 3959ENSG00000108679 LGALS3BP chr17 76975929 promoter-TSS (NM_005567) −24NM_005567 3959 ENSG00000108679 LGALS3BP chr17 76976091 promoter-TSS(NM_005567) −186 NM_005567 3959 ENSG00000108679 LGALS3BP chr18 25616449promoter-TSS (NM_001308176) 56 NM_001308176 1000 ENSG00000170558 CDH2chr18 25625460 L2c|LINE|L2 −8955 NM_001308176 1000 ENSG00000170558 CDH2chr18 25677093 intron (NM_001792, intron 2 of 15) −60588 NM_0013081761000 ENSG00000170558 CDH2 chr18 25739161 intron (NM_001792, intron 1 of15) 17833 NM_001792 1000 ENSG00000170558 CDH2 chr18 25757310promoter-TSS (NM_001792) −316 NM_001792 1000 ENSG00000170558 CDH2 chr1831158479 5′ UTR (NM_030632, exon 1 of 12) 396 NM_030632 80816ENSG00000141431 ASXL3 chr18 31158496 exon (NM_030632, exon 1 of 12) 413NM_030632 80816 ENSG00000141431 ASXL3 chr18 31158505 exon (NM_030632,exon 1 of 12) 422 NM_030632 80816 ENSG00000141431 ASXL3 chr18 31158508exon (NM_030632, exon 1 of 12) 425 NM_030632 80816 ENSG00000141431 ASXL3chr18 31158530 exon (NM_030632, exon 1 of 12) 447 NM_030632 80816ENSG00000141431 ASXL3 chr18 31158635 intron (NM_030632, intron 1 of 11)552 NM_030632 80816 ENSG00000141431 ASXL3 chr18 31158746 intron(NM_030632, intron 1 of 11) 663 NM_030632 80816 ENSG00000141431 ASXL3chr18 31185450 intron (NM_030632, intron 1 of 11) 27367 NM_030632 80816ENSG00000141431 ASXL3 chr18 31185451 intron (NM_030632, intron 1 of 11)27368 NM_030632 80816 ENSG00000141431 ASXL3 chr18 31185458 intron(NM_030632, intron 1 of 11) 27375 NM_030632 80816 ENSG00000141431 ASXL3chr18 31185463 intron (NM_030632, intron 1 of 11) 27380 NM_030632 80816ENSG00000141431 ASXL3 chr18 31185472 intron (NM_030632, intron 1 of 11)27389 NM_030632 80816 ENSG00000141431 ASXL3 chr18 31185490 intron(NM_030632, intron 1 of 11) 27407 NM_030632 80816 ENSG00000141431 ASXL3chr18 31187471 exon (NM_030632, exon 2 of 12) 29388 NM_030632 80816ENSG00000141431 ASXL3 chr19 39989435 promoter-TSS (NM_010941) −52NM_203486 10683 ENSG00000090932 DLL3 chr19 39989507 promoter-TSS(NM_016941) 20 NM_016941 10683 ENSG00000090932 DLL3 chr19 39989508promoter-TSS (NM_016941) 21 NM_016941 10683 ENSG00000090932 DLL3 chr1946916741 promoter-TSS (NM_032040) −20 NM_032040 83987 ENSG00000169515CCDC8 chr19 51358071 promoter-TSS (NM_001030048) 0 NM_001030047 354ENSG00000142515 KLK3 chr19 51358077 promoter-TSS (NM_001030048) 6NM_001030048 354 ENSG00000142515 KLK3 chr19 51358086 promoter-TSS(NM_001030048) 15 NM_001030048 354 ENSG00000142515 KLK3 chr19 51358091promoter-TSS (NM_001030048) 20 NM_001030048 354 ENSG00000142515 KLK3chr19 51358105 promoter-TSS (NM_001030048) 34 NM_001030048 354ENSG00000142515 KLK3 chr19 51358112 promoter-TSS (NM_001030048) 41NM_001030048 354 ENSG00000142515 KLK3 chr19 51358128 promoter-TSS(NM_001030048) 57 NM_001030048 354 ENSG00000142515 KLK3 chr19 51360547intron (NM_001030048, intron 2 of 4) 2476 NM_001030048 354ENSG00000142515 KLK3 chr20 3210322 exon (NM_001174089, exon 14 of 20)7951 NM_032034 83959 ENSG00000088836 SLC4A11 chr20 3211106 exon(NM_001174089, exon 12 of 20) 7167 NM_032034 83959 ENSG00000088836SLC4A11 chr20 3218273 promoter-TSS (NM_032034) 0 NM_032034 83959ENSG00000088836 SLC4A11 chr20 3218712 promoter-TSS (NM_032034) 23NM_001174090 83959 ENSG00000088836 SLC4A11 chr20 3219259 promoter-TSS(NM_032034) 477 NM_001363745 83959 ENSG00000088836 SLC4A11 chr20 3219736promoter-TSS (NM_001174089) 0 NM_001363745 83959 ENSG00000088836 SLC4A11chr20 5891976 promoter-TSS (NM_001819) −80 NM_001819 1114ENSG00000089199 CHGB chr20 5892076 promoter-TSS (NM_001819) 20 NM_0018191114 ENSG00000089199 CHGB chr20 5896044 intron (NM_001819, intron 1 of4) 3988 NM_001819 1114 ENSG00000089199 CHGB chr20 20348665 promoter-TSS(NM_002196) 17 NM_002196 3642 ENSG00000173404 INSM1 chr20 22565001promoter-TSS (NM_021784) 0 NM_021784 3170 ENSG00000125798 FOXA2 chr2022565993 promoter-TSS (NM_153675) 35 NM_153675 3170 ENSG00000125798FOXA2 chr21 42839929 intron (NM_005656, intron 12 of 13) 36052NM_001282920 4599 ENSG00000157601 MX1 chr21 42840664 intron (NM_005656,intron 11 of 13) 36787 NM_001282920 4599 ENSG00000157601 MX1 chr2142878431 intron (NM_005656, intron 1 of 13) 1461 NM_001135099 7113ENSG00000184012 TMPRSS2 chr21 42879809 promoter-TSS (NM_001135099) 83NM_001135099 7113 ENSG00000184012 TMPRSS2 chr21 42879892 promoter-TSS(NM_001135099) 0 NM_001135099 7113 ENSG00000184012 TMPRSS2 chr2142879919 promoter-TSS (NM_001135099) −27 NM_001135099 7113ENSG00000184012 TMPRSS2 chr21 42879941 promoter-TSS (NM_001135099) 44NM_005656 7113 ENSG00000184012 TMPRSS2 chr21 42879985 promoter-TSS(NM_001135099) 0 NM_005656 7113 ENSG00000184012 TMPRSS2 chr21 42879986promoter-TSS (NM_001135099) −1 NM_005656 7113 ENSG00000184012 TMPRSS2chr21 42902925 Intergenic −22940 NM_005656 7113 ENSG00000184012 TMPRSS2chr21 42902943 Intergenic −22958 NM_005656 7113 ENSG00000184012 TMPRSS2chrX 49056535 promoter-TSS (NM_003179) 26 NM_003179 6855 ENSG00000102003SYP chrX 49056552 promoter-TSS (NM_003179) 9 NM_003179 6855ENSG00000102003 SYP chrX 49056554 promoter-TSS (NM_003179) 7 NM_0031796855 ENSG00000102003 SYP chrX 49056558 promoter-TSS (NM_003179) 3NM_003179 6855 ENSG00000102003 SYP chrX 49056618 promoter-TSS(NM_003179) −57 NM_003179 6855 ENSG00000102003 SYP chrX 66764365promoter-TSS (NM_001348064) 0 NM_001011645 367 ENSG00000169083 AR chrX66764562 5′ UTR (NM_001348064, exon 1 of 3) 197 NM_001348061 367ENSG00000169083 AR chrX 66764886 5′ UTR (NM_001348064, exon 1 of 3) 521NM_001348061 367 ENSG00000169083 AR chrX 66788631 5′ UTR (NM_001011645,exon 2 of 9) 24266 NM_001348061 367 ENSG00000169083 AR chr1 202039153AluSx1|SINE|Alu −52892 NM_004767 9283 ENSG00000170075 GPR37L1 chr1241206098 AluSx|SINE|Alu −89474 NR_036069 100422856 ENSG00000265831MIR3123 chr2 89530057 Intergenic 418173 NR_039635 100616399ENSG00000265510 MIR4436A chr3 193490472 Intergenic 71326 NR_146718105374285 LINC02038 chr5 1548487 Intergenic −24412 NM_024830 79888ENSG00000153395 LPCAT1 chr5 36521979 Intergenic −84478 NM_001166696 6507ENSG00000079215 SLC1A3 chr5 39390555 exon (NM_001244871, exon 5 of 14)−25958 NM_001737 735 ENSG00000113600 C9 chr5 71146894LSU-rRNA_Hsa|rRNA|rRNA 131792 NM_004291 9607 ENSG00000164326 CARTPT chr5142194123 intron (NM_001349547, intron 1 of 21) 43331 NM_001349547 23092ENSG00000145819 ARHGAP26 chr5 168573593 intron (NM_001271946, intron 4of 35) 117105 NR_030311 693170 ENSG00000207619 MIR585 chr7 2006579L1MEf|LINE|L1 −26372 NM_001304525 8379 ENSG00000002822 MAD1L1 chr77799018 intron (NM_001302350, intron 3 of 4) −40780 NM_002947 6119ENSG00000106399 RPA3 chr7 127841628 CpG −6297 NR_029596 406917ENSG00000207705 MIR129-1 chr7 129912398 LTR88c|LTR|Gypsy? 5695 NM_0018691358 ENSG00000158516 CPA2 chr8 53499560 Intergenic −21570 NM_207413389658 ENSG00000196711 ALKAL1 chr8 61990390 Intergenic −110083 NR_034003100130298 LOC100130298 chr8 69087227 L2c|LINE|L2 −155381 NM_001349478116328 ENSG00000165084 C8orf34 chr8 73479990 exon (NM_004770, exon 2 of3) 30530 NM_004770 9312 ENSG00000182674 KCNB2 chr8 73849054 exon(NM_004770, exon 3 of 3) −72045 NM_017489 7013 ENSG00000147601 TERF1chr8 133070961 MIRb|SINE|MIR 668 NM_001080399 729330 ENSG00000253117OC90 chr8 140727998 Intergenic −12632 NM_001282534 51305 ENSG00000169427KCNK9 chr8 141458926 MIRb|SINE|MIR 8917 NM_001160372 83696ENSG00000167632 TRAPPC9 chr8 141994084 5′ UTR (NM_001352698, exon 2 of36): 17019 NM_001352710 5747 ENSG00000169398 PTK2 chr8 142367954 exon(NM_005293, exon 2 of 2) 9432 NM_005293 2843 ENSG00000204882 GPR20 chr8143395944 intron (NM_001363740, intron 8 of 13); 88599 NM_001366904203062 ENSG00000171045 TSNARE1 chr9 36748433 Intergenic 75163 NR_039686100616289 ENSG00000266255 MIR4475 chr9 38437314 Intergenic −12863NM_001007563 347252 ENSG00000137142 IGFBPL1 chr9 93792388LTR82B|LTR|ERVL 45026 NR_033912 100129316 LOC100129316 chr9 133769512intron (NM_198180, intron 2 of 2) 2687 NM_198180 347148 ENSG00000188710QRFP chr9 134913164 intron (NM_004269, intron 2 of 7) 42090 NM_0012538819442 ENSG00000160563 MED27 chr9 138719304 exon (NM_015447, exon8 of 17)80088 NM_015447 157922 ENSG00000130559 CAMSAP1 chr14 100039425 intron(NM_001144995, intron 1 of 5) 31119 NM_001144995 317762 ENSG00000205476CCDC85C chr18 8660098 CpG 47521 NR_120598 100287082 ENSG00000265962GACAT2 chr18 14917016 Intergenic −29250 NR_104164 400644 ENSG00000266554LINC01443 chr18 25442246 Intergenic 174359 NM_001308176 1000ENSG00000170558 CDH2 chr18 47258089 MLT1K|LTR|ERVL-MaLR 81814 NM_00611110449 ENSG00000167315 ACAA2 chr20 20421462 intron (NM_020343, intron 37of 39) 72714 NM_002196 3642 ENSG00000173404 INSM1 chr20 21563921 intron(NR_109880, intron 1 of 3) 13259 NR_109880 101929625 LINC01727 chr2132546326 intron (NM_001353687, intron 14 of 26) −13069 NM_001353684 7074ENSG00000156299 TIAM1 chr21 46885392 intron (NM_130444, intron 1 of 41)9956 NM_130444 80781 ENSG00000182871 COL18A1 start_hg19 Gene Alias GeneDescription Gene Type chr1 32237823 BAI2 adhesion G protein-coupledreceptor B2 protein-coding chr1 43814069 CDC20A|bA276H19.3|p55CDC celldivision cycle 20 protein-coding chr1 151345023EHMTO|HEL-S-134P|LPSB|MTO|SBP56|SP56|hSBP selenium binding protein 1protein-coding chr1 151810787 — C2CD4D and THEM5 antisense RNA 1 ncRNAchr2 19561227 ODD odd-skipped related transcription factor 1protein-coding chr2 63283706 — orthodenticle homeobox 1 protein-codingchr2 177030050 HOX1D|HOX4|HOX4A|Hox-4.1 homeobox D3 protein-coding chr2201450223 AO|AOH1 aldehyde oxidase 1 protein-coding chr3 50378091123F2|NORE2A|RASSF1A|RDA32|REH3P21 Ras association domain family member1 protein-coding chr3 122296269 ARTD7|BAL3|pART7 poly(ADP-ribose)polymerase family protein-coding member 15 chr3 124860516 — microRNA5092 ncRNA chr5 958708 — uncharacterized LOC100506688 ncRNA chr5 3187966— long intergenic non-protein coding RNA ncRNA 1377 chr5 180230667GLCNAC-TI|GLCT1|GLYT1|GNT-1|GNT-I|GnTI|MGAT mannosyl(alpha-1,3-)-glycoprotein beta- protein-coding1,2-N-acetylglucosaminyltransferase chr6 13014771EIEE70|RPEL|RPEL1|dJ257A7.2 phosphatase and actin regulator 1protein-coding chr6 15505245 BLOC1S8|DBND|HPS7|My031|SDY dystrobrevinbinding protein 1 protein-coding chr6 26271093 H3/h|H3FH histone cluster1 H3 family member g protein-coding chr7 73245339CPE−R|CPER|CPETR|CPETR1|WBSCR8|hCPE−R claudin 4 protein-coding chr7129425230 MIRN183|miR-183|mRNA183 microRNA 183 ncRNA chr8 56852048 —small nucleolar RNA, H/ACAbox 1B snoRNA chr8 99960398 — odd-skippedrelated transciption factor 2 protein-coding chr8 143625497 Arg3.1|hArcactivity regulated cytoskeleton associated protein-coding protein chr8145104006 MA-nSMase sphingomyelin phosphodiesterase 5 pseudo chr116297648 IPFK2|PFK2|iPFK-2 6-phosphofructo-2-kinase/fructose-2,6-protein-coding biphosphatase 3 chr11 22541895 — uncharacterizedLOC100130992 ncRNA chr11 393838 — plakophilin 3 protein-coding chr1147416258 mir-4487 microRNA 4487 ncRNA chr11 63974672KIND3|MIG-2|MIG2B|UNC112C|URP2|URP2SF fermitin family member 3protein-coding chr11 165408329 SPA1 signal-inducedproliferation-associated 1 protein-coding chr11 67204996 CD45-AP|LPAPprotein tyrosine phosphatase receptor type protein-coding C associatedprotein chr11 69469526 BCL1|D11S287E|PRAD1|U21B31 cvclin D1protein-coding chr12 7060087 HCP|HCPH|HPTP1C|PTP-1C|SH-PTP1|SHP-1|SHP-protein tyrosine phosphatase non-receptor protein-coding 1L|SHP1 type 6chr12 53298578 CARD2|CK-8|CK8|CYK8|K2C8|K8|KO keratin 8 protein-codingchr12 95941769 — ubiquitin specific peptidase 44 protein-coding chr12107038917 — uncharacterized LOC100505978 ncRNA chr12 124773568CFM2|FAM101A refilin A protein-coding chr12 124950569CTG26|N-CoR2|SMAP270|SMRT|SMRTE|SMRTE- nuclear receptor corepressor 2protein-coding tau|TNRC14|TRAC|TRAC-1|TRAC1 chr16 1128589 — SSTR5antisense RNA 1 ncRNA chr17 26732020 G21|HCP1|PCFT solute carrier family46 member 1 protein-coding chr17 41363402 — transmembrane protein 106Aprotein-coding chr17 43318510 — MAP3K14 antisense RNA 1 ncRNA chr1779251155 PP1744 solute carrier family 38 member 10 protein-coding chr1780358729 HEXDC hexosaminidase D protein-coding chr17 180847037 ZFP750zinc finger protein 750 protein-coding chr19 2085186MOB-LAK|MOB1C|MOBKL2A|moblak MOB kinase activator 3A protein-codingchr19 2588141 hsa-mir-7850 microRNA 7850 ncRNA chr19 3179264EDG6|LPC1|S1P4|SLP4 sphingosine-1-phosphate receptor 4 protein-codingchr19 10735906 CTL2|PP1292 solute carrier family 44 member 2protein-coding chr19 15568260 — RAS protein activator like 3protein-coding chr19 18872937 EDM1|EPD1|MED|PSACH|THBS5|TSP5 cartilageoligomeric matrix protein protein-coding chr19 35940325 FFA2R|GPR43 freefatty acid receptor 2 protein-coding chr19 42703509 FLAME−3|FLAME3 deatheffector domain containing 2 protein-coding chr22 48027541 —uncharacterized LOC284930 ncRNA chr1 2036183 PKC-ZETA|PKC2 proteinkinase C zeta protein-coding chr1 2309984 — MORN repeat containing 1protein-coding chr1 2379650 PLC-L4|PLC-eta2|PLCL4|PLCeta2 phospholipaseC eta 2 protein-coding chr1 9887711 ALC-ALPHA|CDHR12|CST- calsyntenin 1protein-coding 1|CSTN1|PIK3CD|XB31alpha|alcalpha1|alcalpha2 chr1119870187 — long intergenic non-protein coding RNA ncRNA 1780 chr1150122937 CKIP-1|CKIP1|JBP|OC120 pleckstrin homology domain containingO1 protein-coding chr1 155034908 EFL4|EPLG4|LERK4 ephrin A4protein-coding chr1 156215318 PRdelta progestin and adipoQ receptorfamily protein-coding member 6 chr1 205631878 IPCA-2|IPCA-6|IPCA- solutecarrier family 45 member 3 protein-coding8|IPCA6|PCANAP2|PCANAP6|PCANAP8|PRST chr1 234666987 — long intergenicnon-protein coding RNA ncRNA 1354 chr1 234908126 — uncharacterizedLOC100130249 ncRNA chr1 235805303 — G protein subunit gamma 4protein-coding chr1 246939116 — long intergenic non-protein coding RNAncRNA 1341 chr2 3281230 EIPR-1|TSSC1 EARP complex and GARP complexprotein-coding interacting protein 1 chr2 10567426 ACA67B smallnucleolar RNA, H/ACA box 80B snoRNA chr2 11796686 NTR2 neurotensinreceptor 2 protein-coding chr2 45237589 — SIX homeobox 2 protein-codingchr2 121432974 chr2 172952783 — distal-less homeobox 1 protein-codingchr2 240161519 — uncharacterized LOC85009 ncRNA chr3 134125473 —microRNA 4788 ncRNA chr3 140813669 SSB-4|SSB4 splA/ryanodine receptordomain and SOCS protein-coding box containing 4 chr3 160167217 IFT80-LTRIM59-1FT80 protein ncRNA chr3 183891828 AP50|CLAPM1|mu2 adaptorrelated protein complex 2 subunit protein-coding mu 1 chr4 981385IDA|MPS1 iduronidase alpha-L- protein-coding chr4 1205814 PCAT10 CTBP1antisense RNA ncRNA chr4 7228168 — sortilin related VPS10 domaincontaining protein-coding receptor 2 chr5 92938049 mir-2277 microRNA2277 ncRNA chr5 134827036 — TIFA inhibitor protein-coding chr5 147162061JAMIP2|NECC1 janus kinase and microtubule interacting protein-codingprotein 2 chr5 179588340 — RasGEF domain family member 1C protein-codingchr6 40567217 FIGLER2|KIAA1246|SALM1 leucine rich repeat and fibronectintype III protein-coding domain containing 2 chr6 170449317 —uncharacterized LOC102724511 ncRNA chr6 170578492 — long intergenicnon-protein coding RNA ncRNA 1624 chr7 214477 DMP-4|DMP4|G-CK|GEF-CK|RNSFAM20C golgi associated secretory protein-coding pathway kinase chr7906626 C7orf20|CEE|CGI-20|TRC35 guided entry of tail-anchored proteinsfactor protein-coding 4 chr7 921951 C7orf20|CEE|CGI-20|TRC35 guidedentry of tail-anchored proteins factor protein-coding 4 chr7 2968216NNX3|RMP|gep G protein subunit alpha 12 protein-coding chr7 50628618AADC dopa decarboxylase protein-coding chr7 129912387 — carboxypeptidaseA2 protein-coding chr7 151432920 AAKG|AAKG2|CMH6|H91620p|WPWS proteinkinase AMP-activated non-catalytic protein-coding subunit gamma 2 chr873848837 PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1 telomeric repeat bindingfactor 1 protein-coding chr8 93114050 AML1- RUNX1 partnertranscriptional co-repressor protein-codingMTG8|AML1T1|CBFA2T1|CDR|ETO|MTG8|ZMYND2 1 chr10 670687 — uncharacterizedLOC101930421 ncRNA chr10 123923781 AZU-1|ECTACC transforming acidiccoiled-coil containing protein-coding protein 2 chr11 20625892GLYT-2|GLYT2|HKPX3|NET1 solute carrier family 6 member 5 protein-codingchr11 61449637 C11orf11|DAGL(ALPHA)|DAGLALPHA|NSDDR diacylglycerollipase alpha protein-coding chr11 62211890CC10|CC16|CCPBP|CCSP|UGB|UP-1|UP1 secretoglobin family 1A member 1protein-coding chr12 104852255 C4ST|C4ST-1|C4STI|HSA269537|OCBMDcarbohydrate sulfotransferase 11 protein-coding chr12 110172108 C12orf34family with sequence similarity 222 protein-coding member A chr12125578255 ACSF1|SUR-5 acetoacetyl-CoA synthetase protein-coding chr1491862713 DAPLE|HKRP2|HYC1|KIAA1509|SCA40 coiled-coil domain containing88C protein-coding chr14 95693684 DCR1|Dicer|Dicer1e|GLOW|HERNA|K12H4.8-dicer 1, ribonuclease III protein-coding LIKE|MNG1|RMSE2 chr14 101157815C14orf70 long intergenic non-protein coding RNA ncRNA 523 chr15 89921572LINC00925 MIR9-3 host gene ncRNA chr15 89959557 — uncharacterizedLOC105371031 ncRNA chr15 99194331 IGF1R-AS IGF1R antisense imprintednon-protein ncRNA coding RNA chr16 1195273CACNA1HB|Cav3.2|ECA6|EIG6|HALD4 calcium voltage-gated channel subunitprotein-coding alpha1 H chr16 29324459 RUNDC2C sorting nexin 29pseudogene 2 pseudo chr17 59480574 VETD T-box transcription factor 2protein-coding chr17 60827102 — uncharacterized LOC105371855 ncRNA chr1771744333 — uncharacterized LOC100134391 protein-coding chr17 72350254BTBD17A|LGALS3BPL|TANGO10A BTB domain containing 17 protein-coding chr1773996145 — cyclin dependent kinase 3 protein-coding chr17 76355046ATOD4|CIS3|Cish3|SOCS-3|SSI-3|SSI3 suppressor of cytokine signaling 3protein-coding chr17 78079381 LYAG glucosidase alpha, acidprotein-coding chr17 79223965 C17orf89 NADH:ubiquinone oxidoreductasecomplex protein-coding assembly factors chr17 80019426 DUS1|PP3111dihydrouridine synthase 1 like protein-coding chr17 80052807FAS|OA-519|SDR27X1 fatty acid synthase protein-coding chr17 80372675HEXDC hexosaminidase D protein-coding chr17 80832228 ZFP750 zinc fingerprotein 750 protein-coding chr18 8659409 MTCL1-AS1|MTCL1AS1 gastriccancer associated transcript 2 ncRNA chr18 13136240 C18orf1 low densitylipoprotein receptor class A protein-coding domain containing 4 chr192540807 GADD45BETA|MYD118 grow th arrest and DNA damage inducibleprotein-coding beta chr19 4566300 SEM-SEMA-Y|SEMA-VIB|SEMAN|semaZsemaphorin 6B protein-coding chr19 17790974 Munc13-1 unc-13 homolog Aprotein-coding chr20 20432962 IA-1|IA1 INSM transcriptional repressor 1protein-coding chr20 51589516 C20orf17|OVC10-2|TSH2|ZABC2|ZNF218teashirt zinc finger homeobox 2 protein-coding chr21 38077158HMC13F06|HMC29C01|SIM|bHLHe15 SIM bHLH transcription factor 2protein-coding chr21 43441927 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr1 2036220 PKC-ZETA|PKC2 protein kinase C zetaprotein-coding chr1 2036226 PKC-ZETA|PKC2 protein kinase C zetaprotein-coding chr1 2036232 PKC-ZETA|PKC2 protein kinase C zetaprotein-coding chr1 2036252 PKC-ZETA|PKC2 protein kinase C zetaprotein-coding chr1 2036395 PKC-ZETA|PKC2 protein kinase C zetaprotein-coding chr1 3697617 Vel small integral membrane protein 1 (Velprotein-coding blood group) chr1 3697629 Vel small integral membraneprotein 1 (Vel protein-coding blood group) chr1 3697639 Vel smallintegral membrane protein 1 (Vel protein-coding blood group) chr13697648 Vel small integral membrane protein 1 (Vel protein-coding bloodgroup) chr1 3697654 Vel small integral membrane protein 1 (Velprotein-coding blood group) chr1 3697667 Vel small integral membraneprotein 1 (Vel protein-coding blood group) chr1 3697692 Vel smallintegral membrane protein 1 (Vel protein-coding blood group) chr13697702 Vel small integral membrane protein 1 (Vel protein-coding bloodgroup) chr1 6171653 AKR6A5|HKvbeta2|HKvbeta2.1|HKvbeta2.2|KCNA2B|potassium voltage-gated channel subfamily protein-coding KV-BETA-2 Aregulatory beta subunit 2 chr1 6171833AKR6A5|HKvbeta2|HKvbeta2.1|HKvbeta2.2|KCNA2B| potassium voltage-gatedchannel subfamily protein-coding KV-BETA-2 A regulatory beta subunit 2chr1 6171838 AKR6A5|HKvbeta2|HKvbeta2.1|HKvbeta2.2|KCNA2B| potassiumvoltage-gated channel subfamily protein-coding KV-BETA-2 A regulatorybeta subunit 2 chr1 6171845AKR6A5|HKvbeta2|HKvbeta2.1|HKvbeta2.2|KCNA2B| potassium voltage-gatedchannel subfamily protein-coding KV-BETA-2 A regulatory beta subunit 2chr1 6171867 AKR6A5|HKvbeta2|HKvbeta2.1|HKvbeta2.2|KCNA2B| potassiumvoltage-gated channel subfamily protein-coding KV-BETA-2 A regulatorybeta subunit 2 chr1 9501648 — long intergenic non-protein coding RNAncRNA 2606 chr1 10696021 CAS11|CST|SRG|ZNF693|dJ734G22.1 castor zincfinger 1 protein-coding chr1 10696065 CAS11|CST|SRG|ZNF693|dJ734G22.1castor zinc finger 1 protein-coding chr1 18808323 — kelch domaincontaining 7A protein-coding chr1 18808343 — kelch domain containing 7Aprotein-coding chr1 18808439 — kelch domain containing 7A protein-codingchr1 18808469 — kelch domain containing 7A protein-coding chr1 18808546— kelch domain containing 7A protein-coding chr1 18808583 — kelch domaincontaining 7A protein-coding chr1 18808621 — kelch domain containing 7Aprotein-coding chr1 18808832 — kelch domain containing 7A protein-codingchr1 18808880 — kelch domain containing 7A protein-coding chr1 18808929— kelch domain containing 7A protein-coding chr1 18808938 — kelch domaincontaining 7A protein-coding chr1 18808967 — kelch domain containing 7Aprotein-coding chr1 18808991 — kelch domain containing 7A protein-codingchr1 18809009 — kelch domain containing 7A protein-coding chr1 18809028— kelch domain containing 7A protein-coding chr1 18809041 — kelch domaincontaining 7A protein-coding chr1 18809052 — kelch domain containing 7Aprotein-coding chr1 18809058 — kelch domain containing 7A protein-codingchr1 18809064 — kelch domain containing 7A protein-coding chr1 18809102— kelch domain containing 7A protein-coding chr1 18809112 — kelch domaincontaining 7A protein-coding chr1 18809126 — kelch domain containing 7Aprotein-coding chr1 18809494 — kelch domain containing 7A protein-codingchr1 20141125 — ring finger protein 186 protein-coding chr1 20141136 —ring finger protein 186 protein-coding chr1 20141322 — ring fingerprotein 186 protein-coding chr1 20141344 — ring finger protein 186protein-coding chr1 20141404 — ring finger protein 186 protein-codingchr1 20141442 — ring finger protein 186 protein-coding chr1 20141462 —ring finger protein 186 protein-coding chr1 22195529 — low densitylipoprotein receptor class A protein-coding domain containing 2 chr132252163 BAI2 adhesion G protein-coupled receptor B2 protein-coding chr132252229 BAI2 adhesion G protein-coupled receptor B2 protein-coding chr132252239 BAI2 adhesion G protein-coupled receptor B2 protein-coding chr132252264 BAI2 adhesion G protein-coupled receptor B2 protein-coding chr132252425 BAI2 adhesion G protein-coupled receptor B2 protein-coding chr145103348 — small nucleolar RNA, C/D box 145 snoRNA chr1 45103390 — smallnucleolar RNA, C/D box 145 snoRNA chr1 45106491 — small nucleolar RNA,C/D box 145 snoRNA chr1 156215343 PRdelta progestin and adipoQ receptorfamily protein-coding member 6 chr1 156215371 PRdelta progestin andadipoQ receptor family protein-coding member 6 chr1 156215401 PRdeltaprogestin and adipoQ receptor family protein-coding member 6 chr1156215416 PRdelta progestin and adipoQ receptor family protein-codingmember 6 chr1 156215430 PRdelta progestin and adipoQ receptor familyprotein-coding member 6 chr1 156215445 PRdelta progestin and adipoQreceptor family protein-coding member 6 chr1 156215454 PRdelta progestinand adipoQ receptor family protein-coding member 6 chr1 156215491PRdelta progestin and adipoQ receptor family protein-coding member 6chr1 156215506 PRdelta progestin and adipoQ receptor familyprotein-coding member 6 chr1 156215520 PRdelta progestin and adipoQreceptor family protein-coding member 6 chr1 156215525 PRdelta progestinand adipoQ receptor family protein-coding member 6 chr1 156215530PRdelta progestin and adipoQ receptor family protein-coding member 6chr1 156215563 PRdelta progestin and adipoQ receptor familyprotein-coding member 6 chr1 156215590 PRdelta progestin and adipoQreceptor family protein-coding member 6 chr1 156215601 PRdelta progestinand adipoQ receptor family protein-coding member 6 chr1 156215708PRdelta progestin and adipoQ receptor family protein-coding member 6chr1 156215720 PRdelta progestin and adipoQ receptor familyprotein-coding member 6 chr1 156215726 PRdelta progestin and adipoQreceptor family protein-coding member 6 chr1 156215737 PRdelta progestinand adipoQ receptor family protein-coding member 6 chr1 203259747 — longintergenic non-protein coding RNA ncRNA 1353 chr1 203259757 — longintergenic non-protein coding RNA ncRNA 1353 chr1 203259770 — longintergenic non-protein coding RNA ncRNA 1353 chr1 203259836 — longintergenic non-protein coding RNA ncRNA 1353 chr1 203259850 — longintergenic non-protein coding RNA ncRNA 1353 chr1 203259921 — longintergenic non-protein coding RNA ncRNA 1353 chr1 236311219 TM7SF1 Gprotein-coupled receptor 137B protein-coding chr1 236311342 TM7SF1 Gprotein-coupled receptor 137B protein-coding chr1 237129554 MT1P2metallothionein 1H like 1 protein-coding chr1 237134163 MT1P2metallothionein 1H like 1 protein-coding chr1 237167480 MT1P2metallothionein 1H like 1 protein-coding chr1 237194084ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237194093 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237194098 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237195314 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237195411ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237212336 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237220609 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237220641 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237222098ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237222106 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237235121 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237235204 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237235522ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237235567 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237235607 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237256273 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237256316ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237265786 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237265877 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237267786 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237267812ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237267886 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237306208 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237306260 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237343254ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237359169 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237383690 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodinereceptor 2 protein-coding chr1 237392760 ARVC2|ARVD2|RYR-2|RyR|VTSIPryanodine receptor 2 protein-coding chr1 237408076ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2 protein-coding chr1237408091 ARVC2|ARVD2|RYR-2|RyR|VTSIP ryanodine receptor 2protein-coding chr1 237473057 — microRNA 4428 ncRNA chr1 237473071 —microRNA 4428 ncRNA chr1 237473091 — microRNA 4428 ncRNA chr1 237473164— microRNA 4428 ncRNA chr1 237538162 — microRNA 4428 ncRNA chr1237584276 — microRNA 4428 ncRNA chr1 237661252 — microRNA 4428 ncRNAchr1 237661262 — microRNA 4428 ncRNA chr1 237661322 — microRNA 4428ncRNA chr1 237693526 — microRNA 4428 ncRNA chr1 237693534 — microRNA4428 ncRNA chr1 237699930 — microRNA 4428 ncRNA chr1 237699938 —microRNA 4428 ncRNA chr1 237699988 — microRNA 4428 ncRNA chr1 237809365— microRNA 4428 ncRNA chr1 237815260 — microRNA 4428 ncRNA chr1241402493 mir-3123 microRNA 3123 ncRNA chr1 241402516 mir-3123 microRNA3123 ncRNA chr2 9248023 AMAP2|CENTB3|DDEF2|PAG3|PAP|Pap- ArfGAP with SH3domain, ankyrin repeat protein-coding alpha|SHAG1 and PH domain 2 chr29248368 AMAP2|CENTB3|DDEF2|PAG3|PAP|Pap- ArfGAP with SH3 domain, ankyrinrepeat protein-coding alpha|SHAG1 and PH domain 2 chr2 9248435AMAP2|CENTB3|DDEF2|PAG3|PAP|Pap- ArfGAP with SH3 domain, ankyrin repeatprotein-coding alpha|SHAG1 and PH domain 2 chr2 9248469AMAP2|CENTB3|DDEF2|PAG3|PAP|Pap- ArfGAP with SH3 domain, ankyrin repeatprotein-coding alpha|SHAG1 and PH domain 2 chr2 25299679 KIAA0953 EFR3homolog B protein-coding chr2 25299815 KIAA0953 EFR3 homolog Bprotein-coding chr2 25299928 KIAA0953 EFR3 homolog B protein-coding chr243102420 3-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate 3,4-dioxygenaseprotein-coding chr2 43107259 3-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate3,4-dioxygenase protein-coding chr2 43107400 3-HAO|HAO|VCRL1|h3HAO3-hydroxyanthramlate 3,4-dioxygenase protein-coding chr2 431074143-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate 3,4-dioxygenaseprotein-coding chr2 43107438 3-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate3,4-dioxygenase protein-coding chr2 43107456 3-HAO|HAO|VCRL1|h3HAO3-hydroxyanthramlate 3,4-dioxygenase protein-coding chr2 431074653-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate 3,4-dioxygenaseprotein-coding chr2 43107514 3-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate3,4-dioxygenase protein-coding chr2 43107532 3-HAO|HAO|VCRL1|h3HAO3-hydroxyanthramlate 3,4-dioxygenase protein-coding chr2 431076503-HAO|HAO|VCRL1|h3HAO 3-hydroxyanthramlate 3,4-dioxygenaseprotein-coding chr2 45235684 — SIX homeobox 2 protein-coding chr245235702 — SIX homeobox 2 protein-coding chr2 45235710 — SIX homeobox 2protein-coding chr2 207972376 mir-2355 microRNA 2355 ncRNA chr2207972408 mir-2355 microRNA 2355 ncRNA chr2 220509654AE3|CAE3/BAE3|SLC2C solute carrier family 4 member 3 protein-coding chr2220509693 AE3|CAE3/BAE3|SLC2C solute carrier family 4 member 3protein-coding chr2 220509705 AE3|CAE3/BAE3|SLC2C solute carrier family4 member 3 protein-coding chr2 220509776 AE3|CAE3/BAE3|SLC2C solutecarrier family 4 member 3 protein-coding chr2 220509830AE3|CAE3/BAE3|SLC2C solute carrier family 4 member 3 protein-coding chr2241233035 glypican glypican 1 protein-coding chr2 241233048 glypicanglypican 1 protein-coding chr2 241233055 glypican glypican 1protein-coding chr2 241233084 glypican glypican 1 protein-coding chr2241233090 glypican glypican 1 protein-coding chr2 241233169 glypicanglypican 1 protein-coding chr2 241233214 glypican glypican 1protein-coding chr3 111431516 LL5b|LL5beta pleckstrin homology likedomain family B protein-coding member 2 chr3 111431559 LL5b|LL5betapleckstrin homology like domain family B protein-coding member 2 chr43309964 — regulator of G protein signaling 12 protein-coding chr43310004 — regulator of G protein signaling 12 protein-coding chr43311787 — regulator of G protein signaling 12 protein-coding chr43311917 — regulator of G protein signaling 12 protein-coding chr47228254 — sortilin related VPS10 domain containing protein-codingreceptor 2 chr4 7228263 — sortilin related VPS10 domain containingprotein-coding receptor 2 chr4 7228304 — sortilin related VPS10 domaincontaining protein-coding receptor 2 chr4 7228329 — sortilin relatedVPS10 domain containing protein-coding receptor 2 chr4 7326173 —microRNA 4798 ncRNA chr4 7326188 — microRNA 4798 ncRNA chr4 7326270 —microRNA 4798 ncRNA chr4 7326284 — microRNA 4798 ncRNA chr4 155758143CT68 RNA binding motif protein 46 protein-coding chr4 155763679 CT68 RNAbinding motif protein 46 protein-coding chr4 155763688 CT68 RNA bindingmotif protein 46 protein-coding chr4 155763695 CT68 RNA binding motifprotein 46 protein-coding chr4 155812513 CT68 RNA binding motif protein46 protein-coding chr4 155912924 CT68 RNA binding motif protein 46protein-coding chr4 155965520 NPY2-R neuropeptide Y receptor Y2protein-coding chr4 155965532 NPY2-R neuropeptide Y receptor Y2protein-coding chr4 155965538 NPY2-R neuropeptide Y receptor Y2protein-coding chr4 155965544 NPY2-R neuropeptide Y receptor Y2protein-coding chr4 155965553 NPY2-R neuropeptide Y receptor Y2protein-coding chr4 155992200 NPY2-R neuropeptide Y receptor Y2protein-coding chr4 156002533 NPY2-R neuropeptide Y receptor Y2protein-coding chr5 1003895 Naked2 NKD inhibitor of WNT signalingpathway protein-coding 2 chr5 1004045 Naked2 NKD inhibitor of WNTsignaling pathway protein-coding 2 chr5 1004051 Naked2 NKD inhibitor ofWNT signaling pathway protein-coding 2 chr5 1004064 Naked2 NKD inhibitorof WNT signaling pathway protein-coding 2 chr5 1004077 Naked2 NKDinhibitor of WNT signaling pathway protein-coding 2 chr5 1004089 Naked2NKD inhibitor of WNT signaling pathway protein-coding 2 chr5 1004118Naked2 NKD inhibitor of WNT signaling pathway protein-coding 2 chr51004128 Naked2 NKD inhibitor of WNT signaling pathway protein-coding 2chr5 1004135 Naked2 NKD inhibitor of WNT signaling pathwayprotein-coding 2 chr5 1004148 Naked2 NKD inhibitor of WNT signalingpathway protein-coding 2 chr5 1004157 Naked2 NKD inhibitor of WNTsignaling pathway protein-coding 2 chr5 1004184 Naked2 NKD inhibitor ofWNT signaling pathway protein-coding 2 chr5 1004198 Naked2 NKD inhibitorof WNT signaling pathway protein-coding 2 chr5 1004234 Naked2 NKDinhibitor of WNT signaling pathway protein-coding 2 chr5 1004243 Naked2NKD inhibitor of WNT signaling pathway protein-coding 2 chr5 1004259Naked2 NKD inhibitor of WNT signaling pathway protein-coding 2 chr51004269 Naked2 NKD inhibitor of WNT signaling pathway orotein-coding 2chr5 1004288 Naked2 NKD inhibitor of WNT signaling pathwayprotein-coding 2 chr5 1004304 Naked2 NKD inhibitor of WNT signalingpathway protein-coding 2 chr5 1004351 Naked2 NKD inhibitor of WNTsignaling pathway protein-coding 2 chr5 1004357 Naked2 NKD inhibitor ofWNT signaling pathway protein-coding 2 chr5 1004365 Naked2 NKD inhibitorof WNT signaling pathway protein-coding 2 chr5 134827336 — TIFAinhibitor protein-coding chr5 134827353 — TIFA inhibitor protein-codingchr5 134827364 — TIFA inhibitor protein-coding chr5 134827378 — TIFAinhibitor protein-coding chr5 138441347 BAP|MSS|ULG5 SIL1 nucleotideexchange factor protein-coding chr5 138441377 BAP|MSS|ULG5 SIL1nucleotide exchange factor protein-coding chr5 138441561 BAP|MSS|ULG5SIL1 nucleotide exchange factor protein-coding chr5 179401802MIRN340|hsa-mir-340|mir-340 microRNA 340 ncRNA chr5 179401833MIRN340|hsa-mir-340|mir-340 microRNA 340 ncRNA chr5 179401843MIRN340|hsa-mir-340|mir-340 microRNA 340 ncRNA chr5 179401853MIRN340|hsa-mir-340|mir-340 microRNA 340 ncRNA chr5 179401872MIRN340|hsa-mir-340|mir-340 microRNA 340 ncRNA chr5 179588495 — RasGEFdomain family member 1C protein-coding chr5 179588504 — RasGEF domainfamily member 1C protein-coding chr5 179588512 — RasGEF domain familymember 1C protein-coding chr5 179588528 — RasGEF domain family member 1Cprotein-coding chr5 179588550 — RasGEF domain family member 1Cprotein-coding chr5 179588590 — RasGEF domain family member 1Cprotein-coding chr5 179588604 — RasGEF domain family member 1Cprotein-coding chr5 179588617 — RasGEF domain family member 1Cprotein-coding chr5 179588625 — RasGEF domain family member 1Cprotein-coding chr5 179588631 — RasGEF domain family member 1Cprotein-coding chr5 179588672 — RasGEF domain family member 1Cprotein-coding chr5 179588687 — RasGEF domain family member 1Cprotein-coding chr5 179588704 — RasGEF domain family member 1Cprotein-coding chr5 179588719 — RasGEF domain family member 1Cprotein-coding chr5 179597660 — RasGEF domain family member 1Cprotein-coding chr5 179597771 — RasGEF domain family member 1Cprotein-coding chr5 179597812 — RasGEF domain family member 1Cprotein-coding chr6 64151793 GLULD1|LGS lengsin lens protein withglutamine protein-coding synthetase domain chr6 1575497876A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1| AT-rich interaction domain 1Bprotein-coding MRD12|OSA2|P250R chr6 1575497976A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1| AT-rich interaction domain 1Bprotein-coding MRD12|OSA2|P250R chr6 1575498486A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1| AT-rich interaction domain 1Bprotein-coding MRD12|OSA2|P250R chr6 1575504946A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1| AT-rich interaction domain 1Bprotein-coding MRD12|OSA2|P250R chr6 1575505096A3-5|BAF250B|BRIGHT|CSS1|DAN15|ELD/OSA1| AT-rich interaction domain 1Bprotein-coding MRD12|OSA2|P250R chr7 1447696 JRAB|MICAL-L2 MICAL like 2protein-coding chr7 1447734 JRAB|MICAL-L2 MICAL like 2 protein-codingchr7 1447746 JRAB|MICAL-L2 MICAL like 2 protein-coding chr7 1447760JRAB|MICAL-L2 MICAL like 2 protein-coding chr7 1447774 JRAB|MICAL-L2MICAL like 2 protein-coding chr7 1447782 JRAB|MICAL-L2 MICAL like 2protein-coding chr7 2006576 MAD1|PIG9|TP53I9|TXBP181 mitotic arrestdeficient 1 like 1 protein-coding chr7 2006674 MAD1|PIG9|TP53I9|TXBP181mitotic arrest deficient 1 like 1 protein-coding chr7 2007262MAD1|PIG9|TP53I9|TXBP181 mitotic arrest deficient 1 like 1protein-coding chr7 2007279 MAD1|PIG9|TP53I9|TXBP181 mitotic arrestdeficient 1 like 1 protein-coding chr7 2007309 MAD1|PIG9|TP53I9|TXBP181mitotic arrest deficient 1 like 1 protein-coding chr7 2007394MAD1|PIG9|TP53I9|TXBP181 mitotic arrest deficient 1 like 1protein-coding chr7 2968280 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968288 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968314 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968320 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968352 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968357 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968405 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968411 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968426 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968440 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968454 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968489 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968504 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968528 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968552 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968558 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968565 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968585 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968593 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968625 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968684 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 2968706 NNX3|RMP|gep G protein subunit alpha 12protein-coding chr7 26667584 — chromosome 7 open reading frame 71 ncRNAchr7 26667613 — chromosome 7 open reading frame 71 ncRNA chr7 26667674 —chromosome 7 open reading frame 71 ncRNA chr7 26667709 — chromosome 7open reading frame 71 ncRNA chr7 35505816 — uncharacterized LOC401324ncRNA chr7 35505825 — uncharacterized LOC401324 ncRNA chr7 41086116 —long intergenic non-protein coding RNA ncRNA 1449 chr7 41086123 — longintergenic non-protein coding RNA ncRNA 1449 chr7 41086140 — longintergenic non-protein coding RNA ncRNA 1449 chr7 101622017CASP|CDP|CDP/Cut|CDP1|COY1|CUTL1|CUX|Clox| cut like homeobox 1protein-coding Cux/CDP|GDDI|GOLIM6|Nbla10317|p100|p110|p200|p75 chr7101622057 CASP|CDP|CDP/Cut|CDP1|COY1|CUTL1|CUX|Clox| cut like homeobox 1protein-coding Cux/CDP|GDDI|GOLIM6|Nbla10317|p100|p110|p200|p75 chr7101622176 CASP|CDP|CDP/Cut|CDP1|COY1|CUTL1|CUX|Clox| cut like homeobox 1protein-coding Cux/CDP|GDDI|GOLIM6|Nbla10317|p100|p110|p200|p75 chr7115992730 — uncharacterized LOC102724434 ncRNA chr7 115992814 —uncharacterized LOC102724434 ncRNA chr7 115998982 — uncharacterizedLOC102724434 ncRNA chr7 115999026 — uncharacterized LOC102724434 ncRNAchr7 115999448 — uncharacterized LOC102724434 ncRNA chr7 115999464 —uncharacterized LOC102724434 ncRNA chr7 116099337 CAV caveolin 2protein-coding chr7 150668588 ERG-1|ERG1|H- potassium voltage-gatedchannel subfamily protein-coding ERG|HERG|HERG1|Kv11.1|LQT2|SQT1 Hmember 2 chr7 150669120 ERG-1|ERG1|H- potassium voltage-gated channelsubfamily protein-coding ERG|HERG|HERG1|Kv11.1|LQT2|SQT1 H member 2 chr7150811991 AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain,ankyrin protein-coding repeat and PH domain 3 chr7 150812075AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr7 150812111AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr7 150812201AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr7 150812215AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr7 150812398AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr7 150812660AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr7 157423275 MIRN153-2|mir-153-2microRNA 153-2 ncRNA chr7 157623246 — uncharacterized LOC100506585 ncRNAchr8 46929775 ASNSL1 asparagine synthetase pseudogene 1 pseudo chr846935836 ASNSL1 asparagine synthetase pseudogene 1 pseudo chr8 46938035ASNSL1 asparagine synthetase pseudogene 1 pseudo chr8 46938044 ASNSL1asparagine synthetase pseudogene 1 pseudo chr8 46938657 ASNSL1asparagine synthetase pseudogene 1 pseudo chr8 46938693 ASNSL1asparagine synthetase pseudogene 1 pseudo chr8 46938702 ASNSL1asparagine synthetase pseudogene 1 pseudo chr8 46940361 ASNSL1asparagine synthetase pseudogene 1 pseudo chr8 46940406 ASNSL1asparagine synthetase pseudogene 1 pseudo chr8 58062363 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58062426 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58062463 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58096948 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58115010 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58115060 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58115154 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58115225 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58115343 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58115362 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58122819 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58122836 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58122848 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58122861 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58123008 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58126620 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58126666 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58126874 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58127096 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58127515 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58127556 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58127613 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58130004 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58130021 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58130039 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58131654 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58131665 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58131710 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58131715 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58131843 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58131870 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58133184 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58133215 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58133315 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58133743 — longintergenic non-protein coding RNA ncRNA 1606 chr8 58171196 —uncharacterized LOC286177 ncRNA chr8 58171236 — uncharacterizedLOC286177 ncRNA chr8 58192020 C8orf71 long intergenic non-protein codingRNA ncRNA 588 chr8 61777862 — hCG1816373-like ncRNA chr8 61821531 —hCG1816373-like ncRNA chr8 61821546 — hCG1816373-like ncRNA chr861821578 — hCG1816373-like ncRNA chr8 73471538 KV2.2 potassiumvoltage-gated channel subfamily protein-coding B member 2 chr8 73480053KV2.2 potassium voltage-gated channel subfamily protein-coding B member2 chr8 73551842 — uncharacterized LOC101926908 ncRNA chr8 73849013PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1 telomeric repeat binding factor 1protein-coding chr8 73849032 PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1telomeric repeat binding factor 1 protein-coding chr8 73849038PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1 telomeric repeat binding factor 1protein-coding chr8 73849051 PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1telomeric repeat binding factor 1 protein-coding chr8 73849060PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1 telomeric repeat binding factor 1protein-coding chr8 104117894 — long intergenic non-protein coding RNAncRNA 1181 chr8 140929837 — paternally expressed 13 ncRNA chr8 140930939— paternally expressed 13 ncRNA chr8 140931316 — paternally expressed 13ncRNA chr8 142367903 — G protein-coupled receptor 20 protein-coding chr8142367951 — G protein-coupled receptor 20 protein-coding chr8 142367989— G protein-coupled receptor 20 protein-coding chr9 117049844AGP-A|AGP1|HEL-S-153w|ORM orosomucoid 1 protein-coding chr9 117049850AGP-A|AGP1|HEL-S-153w|ORM orosomucoid 1 protein-coding chr9 117049862AGP-A|AGP1|HEL-S-153w|ORM orosomucoid 1 protein-coding chr9 117049885AGP-A|AGP1|HEL-S-153w|ORM orosomucoid 1 protein-coding chr9 127105722 —uncharacterized LOC100129034 ncRNA chr9 127105763 — uncharacterizedLOC100129034 ncRNA chr9 129895923 ARP2|HARP angiopoietin like 2protein-coding chr9 136007375 RGDS|RGF|RalGEF ral guanine nucleotidedissociation protein-coding stimulator chr9 136007484 RGDS|RGF|RalGEFral guanine nucleotide dissociation protein-coding stimulator chr9136007594 RGDS|RGF|RalGEF ral guanine nucleotide dissociationprotein-coding stimulator chr9 136007599 RGDS|RGF|RalGEF ral guaninenucleotide dissociation protein-coding stimulator chr9 136007615RGDS|RGF|RalGEF ral guanine nucleotide dissociation protein-codingstimulator chr9 136007712 RGDS|RGF|RalGEF ral guanine nucleotidedissociation protein-coding stimulator chr9 136324027C9orf7|D9S2135|FLOWER calcium channel flower domain containingprotein-coding 1 chr9 136324037 C9orf7|D9S2135|FLOWER calcium channelflower domain containing protein-coding 1 chr9 136324064C9orf7|D9S2135|FLOWER calcium channel flower domain containingprotein-coding 1 chr9 138688868EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138688876EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138688902EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138688936EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138689094EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138689107EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138689483EIEE14|ENFL5|KCa4.1|SLACK|Slo2.2|bA100C15.2 potassium sodium-activatedchannel protein-coding subfamily T member 1 chr9 138719312 — calmodulinregulated spectrin associated protein-coding protein 1 chr9 138719386 —calmodulin regulated spectrin associated protein-coding protein 1 chr9139419669 — microRNA 4673 ncRNA chr9 139419769 — microRNA 4673 ncRNAchr9 139419814 — microRNA 4673 ncRNA chr9 139419865 — microRNA 4673ncRNA chr9 139419924 — microRNA 4673 ncRNA chr9 139419933 — microRNA4673 ncRNA chr9 139419956 — microRNA 4673 ncRNA chr9 139420550 —microRNA 4673 ncRNA chr9 139420561 — microRNA 4673 ncRNA chr9 139420578— microRNA 4673 ncRNA chr9 139420602 — microRNA 4673 ncRNA chr9139420641 — microRNA 4673 ncRNA chr9 139420862 — microRNA 4673 ncRNAchr9 139420914 — microRNA 4673 ncRNA chr9 139421144 — microRNA 4673ncRNA chr9 139421220 — microRNA 4673 ncRNA chr9 139421241 — microRNA4673 ncRNA chr9 139421257 — microRNA 4673 ncRNA chr9 139421267 —microRNA 4673 ncRNA chr9 139421321 — microRNA 4673 ncRNA chr9 139421342— microRNA 4673 ncRNA chr9 139421362 — microRNA 4673 ncRNA chr9139422178 — microRNA 4673 ncRNA chr9 139422203 — microRNA 4673 ncRNAchr9 139422218 — microRNA 4673 ncRNA chr9 139422266 — microRNA 4673ncRNA chr9 139422290 — microRNA 4673 ncRNA chr9 139422314 — microRNA4673 ncRNA chr10 23976532 EIL4|SKT KIAA1217 protein-coding chr1023976581 EIL4|SKT KIAA1217 protein-coding chr10 72489844C10orf27|SPATIAL thymus, brain and testes associated protein-codingchr10 72489870 C10orf27|SPATIAL thymus, brain and testes associatedprotein-coding chr10 72489889 C10orf27|SPATIAL thymus, brain and testesassociated protein-coding chr10 72489949 C10orf27|SPATIAL thymus, brainand testes associated protein-coding chr10 72489967 C10orf27|SPATIALthymus, brain and testes associated protein-coding chr10 72489983C10orf27|SPATIAL thymus, brain and testes associated protein-codingchr10 119590052 C10orf5 cancer susceptibility 2 ncRNA chr10 134562610GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563052GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563060GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563098GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563109GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563144GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563149GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563186GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr10 134563199GTX|NKX6.2|NKX6B|SPAX8 NK6 homeobox 2 protein-coding chr11 2495501ATFB1|ATFB3|JLNS1|KCNA8|KCNA9|KVLQT1| potassium voltage-gated channelsubfamily protein-coding Kv1.9|Kv7.1|LQT|LQT1|RWS|SQT2|WRS Q member 1chr11 2495543 ATFB1|ATFB3|JLNS1|KCNA8|KCNA9|KVLQT1| potassiumvoltage-gated channel subfamily protein-codingKv1.9|Kv7.1|LQT|LQT1|RWS|SQT2|WRS Q member 1 chr11 2495585ATFB1|ATFB3|JLNS1|KCNA8|KCNA9|KVLQT1| potassium voltage-gated channelsubfamily protein-coding Kv1.9|Kv7.1|LQT|LQT1|RWS|SQT2|WRS Q member 1chr11 2495609 ATFB1|ATFB3|JLNS1|KCNA8|KCNA9|KVLQT1| potassiumvoltage-gated channel subfamily protein-codingKv1.9|Kv7.1|LQT|LQT1|RWS|SQT2|WRS Q member 1 chr11 68967954 —uncharacterized LOC338694 ncRNA chr11 68967994 — uncharacterizedLOC338694 ncRNA chr11 68968016 — uncharacterized LOC338694 ncRNA chr1168968032 — uncharacterized LOC338694 ncRNA chr11 68968042 —uncharacterized LOC338694 ncRNA chr11 68968141 — uncharacterizedLOC338694 ncRNA chr11 68968151 — uncharacterized LOC338694 ncRNA chr1168968156 — uncharacterized LOC338694 ncRNA chr11 68968182 —uncharacterized LOC338694 ncRNA chr11 68968214 — uncharacterizedLOC338694 ncRNA chr11 68968240 — uncharacterized LOC338694 ncRNA chr1168968267 — uncharacterized LOC338694 ncRNA chr11 70851529AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851574AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851603AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851619AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851638AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851713AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851722AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851730AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851827AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851836AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851859AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851868AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851883AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851889AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70851914AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70862301AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70862379AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70862397AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 70862405AUTS17|CORTBP1|CTTNBP1|ProSAP1| SH3 and multiple ankyrin repeat domains2 protein-coding SHANK|SPANK-3 chr11 111265961 BOB1|OBF-1|OBF1|OCAB POUclass 2 homeobox associating factor 1 protein-coding chr11 111266000BOB1|OBF-1|OBF1|OCAB POU class 2 homeobox associating factor 1protein-coding chr11 111266014 BOB1|OBF-1|OBF1|OCAB POU class 2 homeoboxassociating factor 1 protein-coding chr11 111266031 BOB1|OBF-1|OBF1|OCABPOU class 2 homeobox associating factor 1 protein-coding chr11 111266119BOB1|OBF-1|OBF1|OCAB POU class 2 homeobox associating factor 1protein-coding chr11 115829517 — long intergenic non-protein coding RNAncRNA 900 chr11 115829550 — long intergenic non-protein coding RNA ncRNA900 chr11 115830020 — long intergenic non-protein coding RNA ncRNA 900chr11 115830200 — long intergenic non-protein coding RNA ncRNA 900 chr11133902554 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902596 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902615 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902626 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902656 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902669 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902689 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902724 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902737 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902744 — long intergenic non-protein coding RNA ncRNA 2731 chr11133902766 — long intergenic non-protein coding RNA ncRNA 2731 chr121957456 — leucine rich repeats and transmembrane protein-coding domains2 chr12 1957466 — leucine rich repeats and transmembrane protein-codingdomains 2 chr12 1957486 — leucine rich repeats and transmembraneprotein-coding domains 2 chr12 1957501 — leucine rich repeats andtransmembrane protein-coding domains 2 chr12 1957566 — leucine richrepeats and transmembrane protein-coding domains 2 chr12 34488345ALG1OA|DIE2|KCR1 ALG10 alpha-1,2-glucosyltransferase protein-codingchr12 34488352 ALG1OA|DIE2|KCR1 ALG10 alpha-1,2-glucosyltransferaseprotein-coding chr12 66111480 — uncharacterized LOC100507065 ncRNA chr1266111548 — uncharacterized LOC100507065 ncRNA chr12 66114657 —uncharacterized LOC100507065 ncRNA chr12 66114687 — uncharacterizedLOC100507065 ncRNA chr12 66114695 — uncharacterized LOC100507065 ncRNAchr12 66262212 — HMGA2 antisense RNA 1 ncRNA chr12 66262228 — HMGA2antisense RNA 1 ncRNA chr12 115109512 TBX3-ISO|UMS|XHL T-boxtranscription factor 3 protein-coding chr12 115109529 TBX3-ISO|UMS|XHLT-box transcription factor 3 protein-coding chr12 115109718TBX3-ISO|UMS|XHL T-box transcription factor 3 protein-coding chr12115109960 TBX3-ISO|UMS|XHL T-box transcription factor 3 protein-codingchr12 115112024 TBX3-ISO|UMS|XHL T-box transcription factor 3protein-coding chr12 115112037 TBX3-ISO|UMS|XHL T-box transcriptionfactor 3 protein-coding chr12 124947867CTG26|N-CoR2|SMAP270|SMRT|SMRTE|SMRTE- nuclear receptor corepressor 2protein-coding tau|TNRC14|TRAC|TRAC-1|TRAC1 chr12 124948139CTG26|N-CoR2|SMAP270|SMRT|SMRTE|SMRTE- nuclear receptor corepressor 2protein-coding tau|TNRC14|TRAC|TRAC-1|TRAC1 chr13 114523664 — GAS6antisense RNA 1 ncRNA chr13 114523669 — GAS6 antisense RNA 1 ncRNA chr13114523717 — GAS6 antisense RNA 1 ncRNA chr13 114523760 — GAS6 antisenseRNA 1 ncRNA chr13 114523787 — GAS6 antisense RNA 1 ncRNA chr13 114523796— GAS6 antisense RNA 1 ncRNA chr13 114523819 — GAS6 antisense RNA 1ncRNA chr13 114523826 — GAS6 antisense RNA 1 ncRNA chr13 114523875 —GAS6 antisense RNA 1 ncRNA chr13 114523883 — GAS6 antisense RNA 1 ncRNAchr13 114523896 — GAS6 antisense RNA 1 ncRNA chr13 114523904 — GAS6antisense RNA 1 ncRNA chr13 114523923 — GAS6 antisense RNA 1 ncRNA chr13114523948 — GAS6 antisense RNA 1 ncRNA chr13 114523958 — GAS6 antisenseRNA 1 ncRNA chr13 114523970 — GAS6 antisense RNA 1 ncRNA chr13 114523982— GAS6 antisense RNA 1 ncRNA chr13 114523996 — GAS6 antisense RNA 1ncRNA chr13 114524029 — GAS6 antisense RNA 1 ncRNA chr13 114524093 —GAS6 antisense RNA 1 ncRNA chr13 114524130 — GAS6 antisense RNA 1 ncRNAchr13 114524137 — GAS6 antisense RNA 1 ncRNA chr13 114524149 — GAS6antisense RNA 1 ncRNA chr13 114524157 — GAS6 antisense RNA 1 ncRNA chr13114524420 — GAS6 antisense RNA 1 ncRNA chr13 114524429 — GAS6 antisenseRNA 1 ncRNA chr13 114524439 — GAS6 antisense RNA 1 ncRNA chr13 114524473— GAS6 antisense RNA 1 ncRNA chr13 114524509 — GAS6 antisense RNA 1ncRNA chr13 114524517 — GAS6 antisense RNA 1 ncRNA chr13 114524583 —GAS6 antisense RNA 1 ncRNA chr14 20684518 — olfactory receptor family 11subfamily H protein-coding member 6 chr14 20684528 — olfactory receptorfamily 11 subfamily H protein-coding member 6 chr14 76957115DFNB35|ERR2|ERRb|ESRL2|NR3B2 estrogen related receptor betaprotein-coding chr14 76957138 DFNB35|ERR2|ERRb|ESRL2|NR3B2 estrogenrelated receptor beta protein-coding chr14 76957152DFNB35|ERR2|ERRb|ESRL2|NR3B2 estrogen related receptor betaprotein-coding chr14 76957199 DFNB35|ERR2|ERRb|ESRL2|NR3B2 estrogenrelated receptor beta protein-coding chr14 93423461 CGA chromogranin Aprotein-coding chr14 93423503 CGA chromogranin A protein-coding chr1493423558 CGA chromogranin A protein-coding chr14 93425210 CGAchromogranin A protein-coding chr14 93425284 CGA chromogranin Aprotein-coding chr14 93425331 CGA chromogranin A protein-coding chr1493425520 CGA chromogranin A protein-coding chr14 93425529 CGAchromogranin A protein-coding chr14 93425655 CGA chromogranin Aprotein-coding chr14 93425687 CGA chromogranin A protein-coding chr1493425735 CGA chromogranin A protein-coding chr14 93425741 CGAchromogranin A protein-coding chr14 93426221 CGA chromogranin Aprotein-coding chr14 93426229 CGA chromogranin A protein-coding chr1493426247 CGA chromogranin A protein-coding chr14 93426257 CGAchromogranin A protein-coding chr14 93426336 CGA chromogranin Aprotein-coding chr14 93426381 CGA chromogranin A protein-coding chr1493426456 CGA chromogranin A protein-coding chr14 93426481 CGAchromogranin A protein-coding chr14 93426499 CGA chromogranin Aprotein-coding chr14 93426875 CGA chromogranin A protein-coding chr1493426916 CGA chromogranin A protein-coding chr14 101158277 C14orf70 longintergenic non-protein coding RNA ncRNA 523 chr14 101158294 C14orf70long intergenic non-protein coding RNA ncRNA 523 chr14 101159404DLK|DLK-1|Delta1|FA1|PREF1|Pref-1|ZOG|pG2 delta like non-canonical Notchligand 1 protein-coding chr14 101159430DLK|DLK-1|Delta1|FA1|PREF1|Pref-1|ZOG|pG2 delta like non-canonical Notchligand 1 protein-coding chr14 101159551DLK|DLK-1|Delta1|FA1|PREF1|Pref-1|ZOG|pG2 delta like non-canonical Notchligand 1 protein-coding chr14 101250153 — microRNA 2392 ncRNA chr14101250165 — microRNA 2392 ncRNA chr14 101250240 — microRNA 2392 ncRNAchr14 101250254 — microRNA 2392 ncRNA chr14 101250279 — microRNA 2392ncRNA chr14 101640895 — long intergenic non-protein coding RNA ncRNA2285 chr14 101640910 — long intergenic non-protein coding RNA ncRNA 2285chr14 101640942 — long intergenic non-protein coding RNA ncRNA 2285chr14 101640959 — long intergenic non-protein coding RNA ncRNA 2285chr14 105347685 — microRNA 12121 ncRNA chr14 105347700 — microRNA 12121ncRNA chr14 105347712 — microRNA 12121 ncRNA chr14 105347802 — microRNA12121 ncRNA chr14 105347810 — microRNA 12121 ncRNA chr14 105347834 —microRNA 12121 ncRNA chr14 105347851 — microRNA 12121 ncRNA chr14105347961 — microRNA 12121 ncRNA chr15 22559959 — arginine-glutamic aciddipeptide repeats pseudo pseudogene 3 chr15 22559966 — arginine-glutamicacid dipeptide repeats pseudo pseudogene 3 chr15 22567152 —arginine-glutamic acid dipeptide repeats pseudo pseudogene 3 chr1522567172 — arginine-glutamic acid dipeptide repeats pseudo pseudogene 3chr15 22571751 — arginine-glutamic acid dipeptide repeats pseudopseudogene 3 chr15 22571783 — arginine-glutamic acid dipeptide repeatspseudo pseudogene 3 chr15 22581845 — arginine-glutamic acid dipeptiderepeats pseudo pseudogene 3 chr15 22581981 — arginine-glutamic aciddipeptide repeats pseudo pseudogene 3 chr15 74521143 CT61|HP11097coiled-coil domain containing 33 protein-coding chr15 74521156CT61|HP11097 coiled-coil domain containing 33 protein-coding chr1574521297 CT61|HP11097 coiled-coil domain containing 33 protein-codingchr15 74521344 CT61|HP11097 coiled-coil domain containing 33protein-coding chr15 74521357 CT61|HP11097 coiled-coil domain containing33 protein-coding chr15 74521364 CT61|HP11097 coiled-coil domaincontaining 33 protein-coding chr15 94613752 — long intergenicnon-protein coding RNA ncRNA 1581 chr15 94613766 — long intergenicnon-protein coding RNA ncRNA 1581 chr15 94613787 — long intergenicnon-protein coding RNA ncRNA 1581 chr15 94613823 — long intergenicnon-protein coding RNA ncRNA 1581 chr15 94613901 — long intergenicnon-protein coding RNA ncRNA 1581 chr17 915606 mir-3183 microRNA 3183ncRNA chr17 915643 mir-3183 microRNA 3183 ncRNA chr17 915806 mir-3183microRNA 3183 ncRNA chr17 915890 mir-3183 microRNA 3183 ncRNA chr17915912 mir-3183 microRNA 3183 ncRNA chr17 7010397ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2 asialoglycoprotein receptor 2protein-coding chr17 7010445 ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2asialoglycoprotein receptor 2 protein-coding chr17 7010504ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2 asialoglycoprotein receptor 2protein-coding chr17 7010533 ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2asialoglycoprotein receptor 2 protein-coding chr17 7010548ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2 asialoglycoprotein receptor 2protein-coding chr17 7010630 ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2asialoglycoprotein receptor 2 protein-coding chr17 7010663ASGP-R2|ASGPR2|CLEC4H2|HBXBP|HL-2 asialoglycoprotein receptor 2protein-coding chr17 10728383 — phosphoinositide interacting regulatorof protein-coding transient receptor potential channels chr17 10740512 —phosphoinositide interacting regulator of protein-coding transientreceptor potential channels chr17 10740558 — phosphoinositideinteracting regulator of protein-coding transient receptor potentialchannels chr17 10740569 — phosphoinositide interacting regulator ofprotein-coding transient receptor potential channels chr17 10740581 —phosphoinositide interacting regulator of protein-coding transientreceptor potential channels chr17 10740595 — phosphoinositideinteracting regulator of protein-coding transient receptor potentialchannels chr17 17677711 NCRNA00034 Smith-Magenis syndrome chromosomencRNA region, candidate 5 chr17 17677757 NCRNA00034 Smith-Magenissyndrome chromosome ncRNA region, candidate 5 chr17 17677887 NCRNA00034Smith-Magenis syndrome chromosome ncRNA region, candidate 5 chr1721286388 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286444 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286486 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286510 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286534 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286708 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286741 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 21286747 IRK-2|IRK2|KCNJN1|Kir2.2|Kir2.2v|hIRK|hIRK1| potassiumvoltage-gated channel subfamily protein-coding hkir2.2x|kcnj12x member12 chr17 28299552 — EF-hand calcium binding domain 5 protein-codingchr17 28299565 — EF-hand calcium binding domain 5 protein-coding chr1728299571 — EF-hand calcium binding domain 5 protein-coding chr1728299598 — EF-hand calcium binding domain 5 protein-coding chr1728299697 — EF-hand calcium binding domain 5 protein-coding chr1771715903 — uncharacterized LOC100134391 protein-coding chr17 71715940 —uncharacterized LOC100134391 protein-coding chr17 71715947 —uncharacterized LOC100134391 protein-coding chr17 71715958 —uncharacterized LOC100134391 protein-coding chr17 71716005 —uncharacterized LOC100134391 protein-coding chr17 71743873 —uncharacterized LOC100134391 protein-coding chr17 71744668 —uncharacterized LOC100134391 protein-coding chr17 71744685 —uncharacterized LOC100134391 protein-coding chr17 71744723 —uncharacterized LOC100134391 protein-coding chr17 71744739 —uncharacterized LOC100134391 protein-coding chr17 78079606 LYAGglucosidase alpha, acid protein-coding chr17 78079613 LYAG glucosidasealpha, acid protein-coding chr17 78079629 LYAG glucosidase alpha, acidprotein-coding chr17 78079641 LYAG glucosidase alpha, acidprotein-coding chr17 78079653 LYAG glucosidase alpha, acidprotein-coding chr17 78395359 — microRNA 4730 ncRNA chr17 78395376 —microRNA 4730 ncRNA chr17 80314127 — testis expressed 19 protein-codingchr17 80314154 — testis expressed 19 protein-coding chr17 809148123-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGal beta-1,3-N-protein-coding T8|beta3GnTL1 acetylglucosaminyltransferase like 1 chr1780915007 3-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGalbeta-1,3-N- protein-coding T8|beta3GnTL1 acetylglucosaminyltransferaselike 1 chr17 80915042 3-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn-UDP-GlcNAc:betaGal beta-1,3-N- protein-coding T8|beta3GnTL1acetylglucosaminyltransferase like 1 chr17 809151603-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGal beta-1,3-N-protein-coding T8|beta3GnTL1 acetylglucosaminyltransferase like 1 chr1780915190 3-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGalbeta-1,3-N- protein-coding T8|beta3GnTL1 acetylglucosaminyltransferaselike 1 chr17 80915238 3-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn-UDP-GlcNAc:betaGal beta-1,3-N- protein-coding T8|beta3GnTL1acetylglucosaminyltransferase like 1 chr17 809152483-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGal beta-1,3-N-protein-coding T8|beta3GnTL1 acetylglucosaminyltransferase like 1 chr1780915270 3-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGalbeta-1,3-N- protein-coding T8|beta3GnTL1 acetylglucosaminyltransferaselike 1 chr17 80915289 3-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn-UDP-GlcNAc:betaGal beta-1,3-N- protein-coding T8|beta3GnTL1acetylglucosaminyltransferase like 1 chr17 809153083-Gn-T8|B3GNT8|BGnT-8|beta-1|beta3Gn- UDP-GlcNAc:betaGal beta-1,3-N-protein-coding T8|beta3GnTL1 acetylglucosaminyltransferase like 1 chr188659649 MTCL1-AS1|MTCL1AS1 gastric cancer associated transcript 2 ncRNAchr18 24348426 LINC01092 prostate cancer associated transcript 18 ncRNAchr18 25366256 CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr1825366262 CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 25366300CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 25366309CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 25442175CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 25442224CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 25442243CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 68166868 — longintergenic non-protein coding RNA ncRNA 1910 chr18 68166878 — longintergenic non-protein coding RNA ncRNA 1910 chr18 77320496 —uncharacterized LOC284240 ncRNA chr18 77320538 — uncharacterizedLOC284240 ncRNA chr18 77320583 — uncharacterized LOC284240 ncRNA chr1877320593 — uncharacterized LOC284240 ncRNA chr18 77320606 —uncharacterized LOC284240 ncRNA chr18 77320672 — uncharacterizedLOC284240 ncRNA chr18 77320695 — uncharacterized LOC284240 ncRNA chr1877320711 — uncharacterized LOC284240 ncRNA chr18 77320739 —uncharacterized LOC284240 ncRNA chr19 883734 DRIP92|THRAP5|TRAP95mediator complex subunit 16 protein-coding chr19 883775DRIP92|THRAP5|TRAP95 mediator complex subunit 16 protein-coding chr19883830 DRIP92|THRAP5|TRAP95 mediator complex subunit 16 protein-codingchr19 883873 DRIP92|THRAP5|TRAP95 mediator complex subunit 16protein-coding chr19 883885 DRIP92|THRAP5|TRAP95 mediator complexsubunit 16 protein-coding chr19 883994 DRIP92|THRAP5|TRAP95 mediatorcomplex subunit 16 protein-coding chr19 884032 DRIP92|THRAP5|TRAP95mediator complex subunit 16 protein-coding chr19 884042DRIP92|THRAP5|TRAP95 mediator complex subunit 16 protein-coding chr19884057 DRIP92|THRAP5|TRAP95 mediator complex subunit 16 protein-codingchr19 884140 DRIP92|THRAP5|TRAP95 mediator complex subunit 16protein-coding chr19 884147 DRIP92|THRAP5|TRAP95 mediator complexsubunit 16 protein-coding chr19 884172 DRIP92|THRAP5|TRAP95 mediatorcomplex subunit 16 protein-coding chr19 884233 DRIP92|THRAP5|TRAP95mediator complex subunit 16 protein-coding chr19 884267DRIP92|THRAP5|TRAP95 mediator complex subunit 16 protein-coding chr19884346 DRIP92|THRAP5|TRAP95 mediator complex subunit 16 protein-codingchr19 2299058 LERN2|LRRN6B leucine rich repeat and Ig domainprotein-coding containing 3 chr19 2299180 LERN2|LRRN6B leucine richrepeat and Ig domain protein-coding containing 3 chr19 2299218LERN2|LRRN6B leucine rich repeat and Ig domain protein-coding containing3 chr19 2299353 LERN2|LRRN6B leucine rich repeat and Ig domainprotein-coding containing 3 chr19 2299390 LERN2|LRRN6B leucine richrepeat and Ig domain protein-coding containing 3 chr19 4566603SEM-SEMA-Y|SEMA-VIB|SEMAN|semaZ semaphorin 6B protein-coding chr194566636 SEM-SEMA-Y|SEMA-VIB|SEMAN|semaZ semaphorin 6B protein-codingchr19 4566642 SEM-SEMA-Y|SEMA-VIB|SEMAN|semaZ semaphorin 6Bprotein-coding chr19 4566653 SEM-SEMA-Y|SEMA-VIB|SEMAN|semaZ semaphorin6B protein-coding chr19 9994121 NOE2|NOELIN2|NOELIN2_V1|OlfColfactomedin 2 protein-coding chr19 9994137 NOE2|NOELIN2|NOELIN2_V1|OlfColfactomedin 2 protein-coding chr19 9994208 NOE2|NOELIN2|NOELIN2_V1|OlfColfactomedin 2 protein-coding chr19 9994219 NOE2|NOELIN2|NOELIN2_V1|OlfColfactomedin 2 protein-coding chr19 9994333 NOE2|NOELIN2|NOELIN2_V1|OlfColfactomedin 2 protein-coding chr19 9994349 NOE2|NOELIN2|NOELIN2_V1|OlfColfactomedin 2 protein-coding chr19 13108021CTF|MRSHSS|NF-1/X|NF1-X|NF1A|SOTOS2 nuclear factor IX protein-codingchr19 13108640 CTF|MRSHSS|NF-1/X|NF1-X|NF1A|SOTOS2 nuclear factor IXprotein-coding chr19 13112778 CTF|MRSHSS|NF-1/X|NF1-X|NF1A|SOTOS2nuclear factor IX protein-coding chr19 13616660APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616810APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616818APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616834APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616868APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616879APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616906APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13616911APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617010APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617018APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617024APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617029APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617058APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617065APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617070APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617082APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617090APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617128APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617140APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617157APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617163APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617169APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617176APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617194APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617208APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617218APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617233APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617241APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617250APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617265APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617288APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617302APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617315APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617321APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617328APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617336APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617364APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617380APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617419APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617465APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617483APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617503APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617512APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617517APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13617541APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13618356APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13618391APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 13700379APCA|BI|CACNL1A4|CAV2.1|EA2|EIEE42|FHM| calcium voltage-gated channelsubunit protein-coding HPCA|MHP|MHP1|SCA6 alpha1 A chr19 18836689MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr19 18837043MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr19 18837091MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr19 18837098MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr19 18837105MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr19 34181556 GALNAC4ST1|GalNAc4ST|PSS3carbohydrate sulfotransferase 8 protein-coding chr19 34181606GALNAC4ST1|GalNAc4ST|PSS3 carbohydrate sulfotransferase 8 protein-codingchr19 34181636 GALNAC4ST1|GalNAc4ST|PSS3 carbohydrate sulfotransferase 8protein-coding chr19 38527887 — small nucleolar RNA, C/D box 152 snoRNAchr19 38527913 — small nucleolar RNA, C/D box 152 snoRNA chr19 38527932— small nucleolar RNA, C/D box 152 snoRNA chr19 38528016 — smallnucleolar RNA, C/D box 152 snoRNA chr19 38528031 — small nucleolar RNA,C/D box 152 snoRNA chr19 38684235 — small nucleolar RNA, C/D box 152snoRNA chr19 38684327 BAF45b|NEUD4|neuro-d4 double PHD fingers 1protein-coding chr19 38684338 BAF45b|NEUD4|neuro-d4 double PHD fingers 1protein-coding chr19 38684363 BAF45b|NEUD4|neuro-d4 double PHD fingers 1protein-coding chr19 48699558 C19orf68 zinc finger SWIM-type containing9 protein-coding chr19 48699578 C19orf68 zinc finger SWIM-typecontaining 9 protein-coding chr19 48699588 C19orf68 zinc fingerSWIM-type containing 9 protein-coding chr19 48699615 C19orf68 zincfinger SWIM-type containing 9 protein-coding chr19 48699628 C19orf68zinc finger SWIM-type containing 9 protein-coding chr19 48699667C19orf68 zinc finger SWIM-type containing 9 protein-coding chr1948699717 C19orf68 zinc finger SWIM-type containing 9 protein-codingchr19 55870392 C19orf16 family with sequence similarity 71 memberprotein-coding E2 chr19 55870402 C19orf16 family with sequencesimilarity 71 member protein-coding E2 chr19 55870407 C19orf16 familywith sequence similarity 71 member protein-coding E2 chr19 55870425C19orf16 family with sequence similarity 71 member protein-coding E2chr19 55870439 C19orf16 family with sequence similarity 71 memberprotein-coding E2 chr19 55870456 C19orf16 family with sequencesimilarity 71 member protein-coding E2 chr19 55870462 C19orf16 familywith sequence similarity 71 member protein-coding E2 chr19 55870471C19orf16 family with sequence similarity 71 member protein-coding E2chr19 55870886 C19orf16 family with sequence similarity 71 memberprotein-coding E2 chr20 20180688 C20orf26|CaM-1P3|dJ1002M8.3|dJ1178H5.4cilia and flagella associated protein 61 protein-coding chr20 20180732C20orf26|CaM-1P3|dJ1002M8.3|dJ1178H5.4 cilia and flagella associatedprotein 61 protein-coding chr20 20188098C20orf26|CaM-1P3|dJ1002M8.3|dJ1178H5.4 cilia and flagella associatedprotein 61 protein-coding chr20 20188151C20orf26|CaM-1P3|dJ1002M8.3|dJ1178H5.4 cilia and flagella associatedprotein 61 protein-coding chr20 20206077 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20232312 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20232336 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20232350 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20232360 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20232370 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20232391 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20376947 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20376962 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377074 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377089 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377110 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377122 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377130 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377162 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377169 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20377206 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20392139 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20392184 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20392215 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20392408 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421295 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421314 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421345 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421371 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421396 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421420 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421459 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 20421486 IA-1|IA1 INSM transcriptionalrepressor 1 protein-coding chr20 31129481 — uncharacterized LOC101929698ncRNA chr20 36923352 BPIFD1|rBPI bactericidal permeability increasingprotein protein-coding chr20 36923369 BPIFD1|rBPI bactericidalpermeability increasing protein protein-coding chr20 36923397BPIFD1|rBPI bactericidal permeability increasing protein protein-codingchr20 61013054 C20orf151 RBBP8 N-terminal like protein-coding chr2061013094 C20orf151 RBBP8 N-terminal like protein-coding chr20 61013113C20orf151 RBBP8 N-terminal like protein-coding chr20 61013148 C20orf151RBBP8 N-terminal like protein-coding chr20 61013167 C20orf151 RBBP8N-terminal like protein-coding chr20 61013187 C20orf151 RBBP8 N-terminallike protein-coding chr20 61013226 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013242 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013251 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013263 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013303 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013339 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013474 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61013515 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61020520 C20orf151 RBBP8 N-terminal likeprotein-coding chr20 61021747 C20orf151 RBBP8 N-terminal likeprotein-coding chr21 43442046 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr21 43442055 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr21 43442083 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr21 43442252 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr21 43442338 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr21 43442384 C21orf121|NCRNA00318|PRED87 ZNF295antisense RNA 1 ncRNA chr21 44836763 MSK|SIK|SIK-1|SIK1B|SNF1LK saltinducible kinase 1 protein-coding chr21 44836797MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1 protein-coding chr21144836823 MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1protein-coding chr21 44836842 MSK|SIK|SIK-1|SIK1B|SNF1LK salt induciblekinase 1 protein-coding chr21 44836924 MSK|SIK|SIK-1|SIK1B|SNF1LK saltinducible kinase 1 protein-coding chr21 44836936MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1 protein-coding chr2144836971 MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1protein-coding chr21 44837026 MSK|SIK|SIK-1|SIK1B|SNF1LK salt induciblekinase 1 protein-coding chr21 44837044 MSK|SIK|SIK-1|SIK1B|SNF1LK saltinducible kinase 1 protein-coding chr21 44837052MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1 protein-coding chr2144837060 MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1protein-coding chr21 44837074 MSK|SIK|SIK-1|SIK1B|SNF1LK salt induciblekinase 1 protein-coding chr21 44837115 MSK|SIK|SIK-1|SIK1B|SNF1LK saltinducible kinase 1 protein-coding chr21 44837132MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1 protein-coding chr2144837157 MSK|SIK|SIK-1|SIK1B|SNF1LK salt inducible kinase 1protein-coding chr21 145653981 B7-H2|B7H2|B7RP- inducible T cellcostimulator ligand protein-coding1|B7RP1|B7h|CD275|GL50|ICOS-L|ICOSL|LICOS chr21 45654156B7-H2|B7H2|B7RP- inducible T cell costimulator ligand protein-coding1|B7RP1|B7h|CD275|GL50|ICOS-L|ICOSL|LICOS chr22 47444997 — TBC1D22Aantisense RNA 1 ncRNA chr22 47445037 — TBC1D22A antisense RNA 1 ncRNAchr22 47447406 — TBC1D22A antisense RNA 1 ncRNA chr22 47447603 —TBC1D22A antisense RNA 1 ncRNA chrX 104458760 — testis expressed 13Aprotein-coding chrX 104692650 — testis expressed 13A protein-coding chrX104804571 NESK Nik related kinase protein-coding chrX 104891135 NESK Nikrelated kinase protein-coding chrX 105016634 NESK Nik related kinaseprotein-coding chrX 105016672 NESK Nik related kinase protein-codingchrX 128926432 753P9|CXorf9|HACS2|SH3D6C|SLY SAM and SH3 domaincontaining 3 protein-coding chr2 209103955HEL-216|HEL-S-26|IDCD|IDH|IDP|IDPC|PICD isocitrate dehydrogenase(NADP(+)) 1, protein-coding cytosolic chr4 106155150 KIAA1546|MDS tetmethylcytosine dioxygenase 2 protein-coding chr4 106155913 KIAA1546|MDStet methylcytosine dioxygenase 2 protein-coding chr4 106156460KIAA1546|MDS tet methylcytosine dioxygenase 2 protein-coding chr4106156742 KIAA1546|MDS tet methylcytosine dioxygenase 2 protein-codingchr4 106157415 KIAA1546|MDS tet methylcytosine dioxygenase 2protein-coding chr4 106164901 KIAA1546|MDS tet methylcytosinedioxygenase 2 protein-coding chr4 106196236 — TET2 antisense RNA 1 ncRNAchr7 33732332 CRIM3|CV-2|CV2 BMP binding endothelial regulatorprotein-coding chr7 140453119 — NDUFB2 antisense RNA 1 ncRNA chr7140481387 — NDUFB2 antisense RNA 1 ncRNA chr7 140481426 — NDUFB2antisense RNA 1 ncRNA chr7 140500421 — NDUFB2 antisense RNA 1 ncRNA chr7140507748 — NDUFB2 antisense RNA 1 ncRNA chr7 140507954 — NDUFB2antisense RNA 1 ncRNA chr7 140624441 B-RAF1B-raf|BRAF 1NS7|R AFB1 B-Rafproto-oncogene, serine/threonine protein-coding kinase chr14 38061176HNF3A|TCF3A forkhead box A1 protein-coding chr14 38061319 HNF3A|TCF3Aforkhead box A1 protein-coding chr14 38061830 HNF3A|TCF3A forkhead boxA1 protein-coding chr17 7572948 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7573967 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7576524 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7576838 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7577020 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7577483 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7578161 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7578373 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7579297 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7579393 BCC7|BMFS5|LFS1|P53[IRP53 tumor proteinp53 protein-coding chr17 7579506 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7579701 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 7579846 BCC7|BMFS5|LFS1|P53|TRP53 tumor proteinp53 protein-coding chr17 47696409 BTBD32|TEF2 speckle type BTB/POZprotein protein-coding chr17 47696673 BTBD32|TEF2 speckle type BTB/POZprotein protein-coding chr20 31375142 ICF|ICF1|M.HsaIIIB DNAmethyltransferase 3 beta protein-coding chr20 31380384ICF|ICF1|M.HsaIIIB DNA methyltransferase 3 beta protein-coding chr2031381300 ICF|ICF1|M.HsaIIIB DNA methyltransferase 3 beta protein-codingchr20 31386255 ICF|ICF1|M.HsaIIIB DNA methyltransferase 3 betaprotein-coding chr20 31388050 EB1 microtubule associated protein RP/EBprotein-coding family member 1 chr20 31389120 EB1 microtubule associatedprotein RP/EB protein-coding family member 1 chr20 31393185 EB1microtubule associated protein RP/EB protein-coding family member 1chr20 31395662 EB1 microtubule associated protein RP/EB protein-codingfamily member 1 chrX 66121000 EDA-A2R|EDAA2R|TNFRSF27|XEDARectodysplasin A2 receptor protein-coding chrX 66766332AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4| androgen receptor protein-codingSBMA|SMAX1|IFM chrX 66931448 AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4|androgen receptor protein-coding SBMA|SMAX1|IFM chrX 66937357AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4| androgen receptor protein-codingSBMA|SMAX1|IFM chrX 66943528 AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4|androgen receptor protein-coding SBMA|SMAX1|IFM chr2 25452399DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alpha protein-coding chr225452969 DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alphaprotein-coding chr2 25453099 DNMT3A2|M.HsaIIIA|TBRS DNAmethyltransferase 3 alpha protein-coding chr2 25453105DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alpha protein-coding chr225453799 DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alphaprotein-coding chr2 25453898 DNMT3A2|M.HsaIIIA|TBRS DNAmethyltransferase 3 alpha protein-coding chr2 25453899DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alpha protein-coding chr225453913 DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alphaprotein-coding chr2 25499982 DNMT3A2|M.HsaIIIA|TBRS DNAmethyltransferase 3 alpha protein-coding chr2 25500271DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alpha protein-coding chr225500272 DNMT3A2|M.HsaIIIA|TBRS DNA methyltransferase 3 alphaprotein-coding chr2 239147428 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239147440C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239147441 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239147485C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239147486 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239147522C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239147534 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239147589C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239147601 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239147614C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239147637 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239147649C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239147665 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr2 239149894C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes family bHLH transcription factor 6protein-coding chr2 239149895 C-HAIRY1|HES-6|bHLHb41|bHLHc23 hes familybHLH transcription factor 6 protein-coding chr3 12838468 TIP120B|Tp120bcullin associated and neddylation protein-coding dissociated 2(putative) chr3 50660608 3PK|MAPKAP-K3|MAPKAP3|MAPKAPK- MAPK activatedprotein kinase 3 protein-coding 3|MDPT3|MK-3 chr3 506701553PK|MAPKAP-K3|MAPKAP3|MAPKAPK- MAPK activated protein kinase 3protein-coding 3|MDPT3|MK-3 chr3 128202781 DCML|IMD21|MONOMAC|NFE1B GATAbinding protein 2 protein-coding chr3 128202787 DCML|IMD21|MONOMAC|NFE1BGATA binding protein 2 protein-coding chr3 128202792DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2 protein-coding chr3128202795 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2 protein-codingchr3 128202796 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2protein-coding chr3 128202884 DCML|IMD21|MONOMAC|NFE1B GATA bindingprotein 2 protein-coding chr3 128202894 DCML|IMD21|MONOMAC|NFE1B GATAbinding protein 2 protein-coding chr3 128202895 DCML|IMD21|MONOMAC|NFE1BGATA binding protein 2 protein-coding chr3 128202927DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2 protein-coding chr3128202928 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2 protein-codingchr3 128205157 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2protein-coding chr3 128205179 DCML|IMD21|MONOMAC|NFE1B GATA bindingprotein 2 protein-coding chr3 128205180 DCML|IMD21|MONOMAC|NFE1B GATAbinding protein 2 protein-coding chr3 128205195 DCML|IMD21|MONOMAC|NFE1BGATA binding protein 2 protein-coding chr3 128205196DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2 protein-coding chr3128205210 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2 protein-codingchr3 128210723 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2protein-coding chr3 128210727 DCML|IMD21|MONOMAC|NFE1B GATA bindingprotein 2 protein-coding chr3 128212207 DCML|IMD21|MONOMAC|NFE1B GATAbinding protein 2 protein-coding chr3 185817004 ERM ETS variant 5protein-coding chr4 16084875 chr4 16084881 chr4 16084898 chr4 16085260AC133|CD133|CORD12|MCDR2|MSTP061|PROML1| prominin 1 protein-codingRP41|STGD4 chr4 16085380 AC133|CD133|CORD12|MCDR2|MSTP061|PROML1|prominin 1 protein-coding RP41|STGD4 chr4 16085396AC133|CD133|CORD12|MCDR2|MSTP061|PROML1| prominin 1 protein-codingRP41|STGD4 chr4 16085398 AC133|CD133|CORD12|MCDR2|MSTP061|PROML1|Rprominin 1 protein-coding P41|STGD4 chr4 16085401AC133|CD133|CORD12|MCDR2|MSTP061|PROML1| prominin 1 protein-codingRP41|STGD4 chr5 172661872 CHNG5|CSX|CSX1|HLHS2|NKX2.5|NKX2E|NKX4- NK2homeobox 5 protein-coding 1|VSD3 chr5 172661874CHNG5|CSX|CSX1|HLHS2|NKX2.5|NKX2E|NKX4- NK2 homeobox 5 protein-coding1|VSD3 chr6 34522044 PDEF|bA375E1.3 SAM pointed domain containing ETSprotein-coding transcription factor chr6 34523223 PDEF|bA375E1.3 SAMpointed domain containing ETS protein-coding transcription factor chr811561726 ASD2|TACHD|TOF|VSD1 GATA binding protein 4 protein-coding chr811565855 ASD2|TACHD|TOF|VSD1 GATA binding protein 4 protein-coding chr811566229 ASD2|TACHD|TOF|VSD1 GATA binding protein 4 protein-coding chr811583613 ASD2|TACHD|TOF|VSD1 GATA binding protein 4 protein-coding chr811583614 ASD2|TACHD|TOF|VSD1 GATA binding protein 4 protein-coding chr9126775063 LH2|hLhx2 LIM homeobox 2 protein-coding chr9 126775082LH2|hLhx2 LIM homeobox 2 protein-coding chr9 126776013 LH2|hLhx2 LIMhomeobox 2 protein-coding chr9 126776231 LH2|hLhx2 LIM homeobox 2protein-coding chr9 139437635 AOS5|AOVD1|TAN1|hN1 notch receptor 1protein-coding chr9 139437679 AOS5|AOVD1|TAN1|hN1 notch receptor 1protein-coding chr10 23481414 PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreasassociated transcription factor 1a protein-coding chr10 23481415PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreas associated transcriptionfactor 1a protein-coding chr10 23481417 PACA|PAGEN2|PTF1-p48|bHLHa29|p48pancreas associated transcription factor 1a protein-coding chr1023481445 PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreas associatedtranscription factor 1a protein-coding chr10 23481447PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreas associated transcriptionfactor 1a protein-coding chr10 23481448 PACA|PAGEN2|PTF1-p48|bHLHa29|p48pancreas associated transcription factor 1a protein-coding chr1023481451 PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreas associatedtranscription factor 1a protein-coding chr10 23481461PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreas associated transcriptionfactor 1a protein-coding chr10 23481462 PACA|PAGEN2|PTF1-p48|bHLHa29|p48pancreas associated transcription factor 1a protein-coding chr1023481463 PACA|PAGEN2|PTF1-p48|bHLHa29|p48 pancreas associatedtranscription factor 1a protein-coding chr10 56699066CDHR15|DFNB23|USH1F protocadherin related 15 protein-coding chr1056699077 CDHR15|DFNB23|USH1F protocadherin related 15 protein-codingchr10 57391015 CDHR15|DFNB23|USH1F protocadherin related 15protein-coding chr11 69451450 BCL1|D11S287E|PRAD1|U21B31 cyclin D1protein-coding chr12 103344993 ASH1|HASH1|MASH1|bHLHa46 achaete-scutefamily bHLH transcription protein-coding factor 1 chr12 103344998ASH1|HASH1|MASH1|bHLHa46 achaete-scute family bHLH transcriptionprotein-coding factor 1 chr12 103345006 ASH1|HASH1|MASH1|bHLHa46achaete-scute family bHLH transcription protein-coding factor 1 chr12103345029 ASH1|HASH1|MASH1|bHLHa46 achaete-scute family bHLHtranscription protein-coding factor 1 chr12 103345033ASH1|HASH1|MASH1|bHLHa46 achaete-scute family bHLH transcriptionprotein-coding factor 1 chr14 51560040 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 51560162 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 51560191 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr11 51560193 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 51560208 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 51560259 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 51560261 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 51560275 RNF91|SPRING tripartite motifcontaining 9 protein-coding chr14 65409361GI-GPx|GPRP|GPRP-2|GPx-2|GPx-GI|GSHPX- glutathione peroxidase 2protein-coding GI|GSHPx-2 chr14 93385930 CGA chromogranin Aprotein-coding chr14 93423499 CGA chromogranin A protein-coding chr1493423555 CGA chromogranin A protein-coding chr14 93425158 CGAchromogranin A protein-coding chr14 93425189 CGA chromogranin Aprotein-coding chr14 93425207 CGA chromogranin A protein-coding chr1493425289 CGA chromogranin A protein-coding chr14 93425328 CGAchromogranin A protein-coding chr14 93425517 CGA chromogranin Aprotein-coding chr14 93425684 CGA chromogranin A protein-coding chr1493425685 CGA chromogranin A protein-coding chr14 93425738 CGAchromogranin A protein-coding chr14 93426226 CGA chromogranin Aprotein-coding chr14 93426244 CGA chromogranin A protein-coding chr1493426333 CGA chromogranin A protein-coding chr14 93426378 CGAchromogranin A protein-coding chr14 93426872 CGA chromogranin Aprotein-coding chr14 93426913 CGA chromogranin A protein-coding chr1493426914 CGA chromogranin A protein-coding chr14 93426959 CGAchromogranin A protein-coding chr14 93439910 CGA chromogranin Aprotein-coding chr18 31323189 BRPS|KIAA1713 ASXL transcriptionalregulator 3 protein-coding chr18 31323202 BRPS|KIAA1713 ASXLtranscriptional regulator 3 protein-coding chr18 53175324E2-2|FECD3|ITF-2|ITF2|PTHS|SEF-2|SEF2|SEF2- transcription factor 4protein-coding 1|SEF2-1A|SEF2-1B|SEF2-1D|TCF-4|bHLHb19 chr18 53305364E2-2|FECD3|ITF-2|ITF2|PTHS|SEF-2|SEF2|SEF2- transcription factor 4protein-coding 1|SEF2-1A|SEF2-1B|SEF2-1D|TCF-4|bHLHb19 chr18 53305490E2-2|FECD3|ITF-2|ITF2|PTHS|SEF-2|SEF2|SEF2- transcription factor 4protein-coding 1|SEF2-1A|SEF2-1B|SEF2-1D|TCF-4|bHLHb19 chr19 11086495BAF190|BAF190A|BRG1|CSS4|MRD16|RTPS2|SNF2| SWI/SNF related, matrixassociated, actin protein-coding SNF2L4|SNF2LB|SWI2|hSNF2b dependentregulator of chromatin, subfamily a, member 4 chr19 39993532 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 39993551 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 39993567 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 39993606 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 42618585OCT2|OTF2|Oct-2 POU class 2 homeobox 2 protein-coding chr19 42618760OCT2|OTF2|Oct-2 POU class 2 homeobox 2 protein-coding chr19 42618787OCT2|OTF2|Oct-2 POU class 2 homeobox 2 protein-coding chr19 42618789OCT2|OTF2|Oct-2 POU class 2 homeobox 2 protein-coding chr19 42618823OCT2|OTF2|Oct-2 POU class 2 homeobox 2 protein-coding chr20 20232309IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232319IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232333IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232347IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232348IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232351IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232352IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232357IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232358IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232367IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20232388IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20266415IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20376954IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20376969IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20377086IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20377158IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20377165IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20421292IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20421311IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20421456IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20421483IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433160IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433163IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433166IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433198IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433208IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433248IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433256IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433263IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433284IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 20433293IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 21490704NKX2.2|NKX2B NK2 homeobox 2 protein-coding chr20 21490799 NKX2.2|NKX2BNK2 homeobox 2 protein-coding chr20 21490807 NKX2.2|NKX2B NK2 homeobox 2protein-coding chr20 21494139 NKX2.2|NKX2B NK2 homeobox 2 protein-codingchr20 21494141 NKX2.2|NKX2B NK2 homeobox 2 protein-coding chr20 21494237NKX2.2|NKX2B NK2 homeobox 2 protein-coding chr21 22564429 NCAM21 neuralcell adhesion molecule 2 protein-coding chr21 42850711 PP9284|PRSS10transmembrane serine protease 2 protein-coding chr21 42860322PP9284|PRSS10 transmembrane serine protease 2 protein-coding chr2142860341 PP9284|PRSS10 transmembrane serine protease 2 protein-codingchr21 42880610 PP9284|PRSS10 transmembrane serine protease 2protein-coding chr21 42880614 PP9284|PRSS10 transmembrane serineprotease 2 protein-coding chr21 42880659 PP9284|PRSS10 transmembraneserine protease 2 protein-coding chr21 42880668 PP9284|PRSS10transmembrane serine protease 2 protein-coding chr1 3052478 — microRNA4251 ncRNA chr1 26735081 CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A lin-28homolog A protein-coding chr1 26735241 CSDD1|LIN-28|LIN28|ZCCHC1|lin-28Alin-28 homolog A protein-coding chr1 26735243CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A lin-28 homolog A protein-coding chr126735251 CSDD1|LIN-28|LIN28|ZCCHC1|lin-28A lin-28 homolog Aprotein-coding chr1 65721361 DJC6|PARK19 DnaJ heat shock protein family(Hsp40) protein-coding member C6 chr1 229195756 — microRNA 4454 ncRNAchr2 23807028 KBTBD9 kelch like family member 29 protein-coding chr2171679652 CPSQ1|GAD|SCP glutamate decarboxylase 1 protein-coding chr2236877206 — gastrulation brain homeobox 2 protein-coding chr2 242549633CGI-36|Nb(III)|PP238 THAP domain containing 4 protein-coding chr2242549635 CGI-36|Nb(III)|PP238 THAP domain containing 4 protein-codingchr2 242549638 CGI-36|Nb(III)|PP238 THAP domain containing 4protein-coding chr2 242549659 CGI-36|Nb(III)|PP238 THAP domaincontaining 4 protein-coding chr3 26664523 LRP15 leucine rich repeatcontaining 3B protein-coding chr3 126664525 LRP15 leucine rich repeatcontaining 3B protein-coding chr3 111431556 LL5b|LL5beta pleckstrinhomology like domain family B protein-coding member 2 chr4 169799044CGI-151|CGI151|MYN|PNCA1|SIH002 palladin, cytoskeletal associatedprotein protein-coding chr5 138441347 BAP|MSS|ULG5 SIL1 nucleotideexchange factor protein-coding chr5 138441374 BAP|MSS|ULG5 SIL1nucleotide exchange factor protein-coding chr5 138441376 BAP|MSS|ULG5SIL1 nucleotide exchange factor protein-coding chr5 176038510 GRIN1 Gprotein regulated inducer of neurite protein-coding outgrowth 1 chr5176038524 GRIN1 G protein regulated inducer of neurite protein-codingoutgrowth 1 chr5 176038525 GRIN1 G protein regulated inducer of neuriteprotein-coding outgrowth 1 chr5 176038562 GRIN1 G protein regulatedinducer of neurite protein-coding outgrowth 1 chr5 179401799MIRN340|hsa-mir-340|mir-340 microRNA 340 ncRNA chr6 15265454 JMJ jumonjiand AT-rich interaction domain protein-coding containing 2 chr6168462402 bA164L23.1 FERM domain containing 1 protein-coding chr6168462447 bA164L23.1 FERM domain containing 1 protein-coding chr6170578588 — long intergenic non-protein coding RNA ncRNA 1624 chr72968311 NNX3|RMP|gep G protein subunit alpha 12 protein-coding chr72968441 NNX3|RMP|gep G protein subunit alpha 12 protein-coding chr72968442 NNX3|RMP|gep G protein subunit alpha 12 protein-coding chr72968451 NNX3|RMP|gep G protein subunit alpha 12 protein-coding chr72968454 NNX3|RMP|gep G protein subunit alpha 12 protein-coding chr75572006 BRWS1|PS1TP5BP1 actin beta protein-coding chr7 150812220AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3 ArfGAP with GTPase domain, ankyrinprotein-coding repeat and PH domain 3 chr8 47570600 ASNSL1 asparaginesynthetase pseudogene 1 pseudo chr9 116411412 C2PA|RGP3 regulator of Gprotein signaling 3 protein-coding chr9 124498726AF9Q34|AIP-1|AIP1|DIP1/2 DAB2nteracting protein protein-coding chr9124620057 AF9Q34|AIP-1|AIP1|DIP1/2 DAB2nteracting protein protein-codingchr10 676777 — uncharacterized LOC101930421 ncRNA chr10 676811 —uncharacterized LOC101930421 ncRNA chr11 2000638 — MRPL23 antisense RNA1 ncRNA chr11 11600192 GALNACT18|GALNT15|GALNTL4|GalNAc- polypeptide N-protein-coding T15|GalNAc-T18 acetylgalactosaminyltransferase 18 chr1111600210 GALNACT18|GALNT15|GALNTL4|GalNAc- polypeptide N- protein-codingT15|GalNAc-T18 acetylgalactosaminyltransferase 18 chr11 11600228GALNACT18|GALNT15|GALNTL4|GalNAc- polypeptide N- protein-codingT15|GalNAc-T18 acetylgalactosaminyltransferase 18 chr11 11600230GALNACT18|GALNT15|GALNTL4|GalNAc- polypeptide N- protein-codingT15|GalNAc-T18 acetylgalactosaminyltransferase 18 chr11 11600231GALNACT18|GALNT15|GALNTL4|GalNAc- polypeptide N- protein-codingT15|GalNAc-T18 acetylgalactosaminyltransferase 18 chr11 11600240GALNACT18|GALNT15|GALNTL4|GalNAc- polypeptide N- protein-codingT15|GalNAc-T18 acetylgalactosaminyltransferase 18 chr11 64120601MSK2|RSK-B|S6K-alpha-4 ribosomal protein S6 kinase A4 protein-codingchr11 70851727 AUTS17|CORTBP1|CTTNBP1|ProSAP1|SHANK| SH3 and multipleankyrin repeat domains 2 protein-coding SPANK-3 chr12 40618451AURA17|DARDARIN|PARK8|RIPK7|ROCO2 leucine rich repeat kinase 2protein-coding chr12 40618493 AURA17|DARDARIN|PARK8|RIPK7|ROCO2 leucinerich repeat kinase 2 protein-coding chr15 32385689 CHRNA7-2|NACHRA7cholinergic receptor nicotinic alpha 7 protein-coding subunit chr1568723747 HsT18964 integrin subunit alpha 11 protein-coding chr1589954601 — uncharacterized LOC105371031 ncRNA chr15 89954603 —uncharacterized LOC105371031 ncRNA chr15 89954605 — uncharacterizedLOC105371031 ncRNA chr15 89959942 — uncharacterized LOC105371031 ncRNAchr16 85498200 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85498219 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85498220 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85498227 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85498781 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519155 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519162 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519165 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519168 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519171 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519173 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 85519303 CRHSP24|KIAA0182 Gse1 coiled-coil protein protein-codingchr16 88715953 p22-PHOX cytochrome b-245 alpha chain protein-codingchr17 28299568 — EF-hand calcium binding domain 5 protein-coding chr1780372745 HEXDC hexosaminidase D protein-coding chr17 80372760 HEXDChexosaminidase D protein-coding chr17 80372761 HEXDC hexosaminidase Dprotein-coding chr17 80372766 HEXDC hexosaminidase D protein-codingchr17 80372767 HEXDC hexosaminidase D protein-coding chr17 80372770HEXDC hexosaminidase D protein-coding chr17 80372771 HEXDChexosaminidase D protein-coding chr17 80372793 HEXDC hexosaminidase Dprotein-coding chr18 57364080 HKLLS1 collagen and calcium binding EGFdomains protein-coding 1 chr19 591647 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591656 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591660 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591662 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591682 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591683 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591684 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591685 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 591688 BCNG-2|BCNG2|HAC-1hyperpolarization activated cyclic protein-coding nucleotide gatedpotassium and sodium channel 2 chr19 18837089MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr19 18837102MAML2|MECT1|Mam-2|TORC-1|TORC1|WAMTP1 CREB regulated transcriptioncoactivator 1 protein-coding chr20 3778162 — cell division cycle 25Bprotein-coding chr20 32156432 EHT|MTGR1|ZMYND3|p85 CBFA2/RUNX1 partnertranscriptional co- protein-coding repressor 2 chr20 48099327 DRK1|Kv2.1potassium voltage-gated channel subfamily protein-coding B member 1chr20 48099339 DRK1|Kv2.1 potassium voltage-gated channel subfamilyprotein-coding B member 1 chrX 36981727 — family with sequencesimilarity 47 member protein-coding C chrX 36981729 — family withsequence similarity 47 member protein-coding C chr1 24392969 — myomesin3 protein-coding chr1 24410522 — myomesin 3 protein-coding chr1 24434829— myomesin 3 protein-coding chr1 24438565 — myomesin 3 protein-codingchr1 27240357 SHP|SHP1 nuclear receptor subfamily 0 group Bprotein-coding member 2 chr1 50513586 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50569482 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50571262 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50571864 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50574505 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50574538 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50575198 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50575278 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50575388 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50610525 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 50642702 HUD|PNEM ELAV like RNA bindingprotein 4 protein-coding chr1 78445126 FBP|FUBP|hDH V far upstreamelement binding protein 1 protein-coding chr1 78511486 SEMCAP-2|SEMCAP2GIPC PDZ domain containing family protein-coding member 2 chr1 114521963HNOEL-iso|OLF44 olfactomedin like 3 protein-coding chr1 114521965HNOEL-iso|OLF44 olfactomedin like 3 protein-coding chr1 114522013HNOEL-iso|OLF44 olfactomedin like 3 protein-coding chr1 114522595HNOEL-iso|OLF44 olfactomedin like 3 protein-coding chr1 152956457 SPRKsmall proline rich protein 1A protein-coding chr1 152957607 SPRK smallproline rich protein 1A protein-coding chr1 15333023060B8AG|CAGB|CFAG|CGLB|L1AG|LIAG| S100 calcium binding protein A9protein-coding MAC387|MIF|MRP14|NIF|P14 chr2 74119341ACT|ACTA3|ACTE|ACTL3|ACTSG|VSCM actin gamma 2, smooth muscleprotein-coding chr2 74119978 ACT|ACTA3|ACTE|ACTL3|ACTSG|VSCM actin gamma2, smooth muscle protein-coding chr2 74119994ACT|ACTA3|ACTE|ACTL3|ACTSG|VSCM actin gamma 2, smooth muscleprotein-coding chr2 74120006 ACT|ACTA3|ACTE|ACTL3|ACTSG|VSCM actin gamma2, smooth muscle protein-coding chr2 74120009ACT|ACTA3|ACTE|ACTL3|ACTSG|VSCM actin gamma 2, smooth muscleprotein-coding chr2 74120035 ACT|ACTA3|ACTE|ACTL3|ACTSG|VSCM actin gamma2, smooth muscle protein-coding chr2 95940101 PROML2 prominin 2protein-coding chr2 95940121 PROML2 prominin 2 protein-coding chr295940140 PROML2 prominin 2 protein-coding chr2 95940145 PROML2 prominin2 protein-coding chr2 95940149 PROML2 prominin 2 protein-coding chr295940627 PROML2 prominin 2 protein-coding chr2 95943464 PROML2 prominin2 protein-coding chr2 95945514 PROML2 prominin 2 protein-coding chr295954155 CSEN|DREAM|KCHIP3 potassium voltage-gated channel interactingprotein-coding protein 3 chr2 95954163 CSEN|DREAM|KCHIP3 potassiumvoltage-gated channel interacting protein-coding protein 3 chr2169921199 3-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699234453-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699234873-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699259663-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699259723-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699259863-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699289103-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 1699375173-alpha-HSD|3ALPHA-HSD|RDH-E2|RDH- dehydrogenase/reductase 9protein-coding TBE|RDH15|RDHL|RDHTBE|RETSDR8|SDR9C4 chr2 177001240 —uncharacterized LOC401021 ncRNA chr2 177001585 — HOXD cluster antisenseRNA 2 ncRNA chr2 177015022 MIRN10B|hsa-mir-10b|miRNA10B|mir-10b microRNA10b ncRNA chr2 177025519 HOX1D|HOX4|HOX4A|Hox-4.1 homeobox D3protein-coding chr2 177028705 HOX1D|HOX4|HOX4A|Hox-4.1 homeobox D3protein-coding chr2 182545174 BETA2|BHF-1|MODY6|NEUROD|bHLHa3 neuronaldifferentiation 1 protein-coding chr2 182545503BETA2|BHF-1|MODY6|NEUROD|bHLHa3 neuronal differentiation 1protein-coding chr2 219696414 AMPKG3 protein kinase AMP-activatednon-catalytic protein-coding subunit gamma 3 chr2 219696424 AMPKG3protein kinase AMP-activated non-catalytic protein-coding subunit gamma3 chr2 219696426 AMPKG3 protein kinase AMP-activated non-catalyticprotein-coding subunit gamma 3 chr2 219696439 AMPKG3 protein kinase AMP-activated non-catalytic protein-coding subunit gamma 3 chr2 219696709AMPKG3 protein kinase AMP -activated non-catalytic protein-codingsubunit gamma 3 chr2 223916432 MIRP3 potassium voltage-gated channelsubfamily protein-coding E regulatory subunit 4 chr2 223916762 MIRP3potassium voltage-gated channel subfamily protein-coding E regulatorysubunit 4 chr2 223916818 MIRP3 potassium voltage-gated channel subfamilyprotein-coding E regulatory subunit 4 chr2 233924577SHIP|SHIP-1|SHIP1|SIP-145|hp51CN|p150Ship inositolpolyphosphate-5-phosphatase D protein-coding chr2 233924962SHIP|SHIP-1|SHIP1|SIP-145|hp51CN|p150Ship inositolpolyphosphate-5-phosphatase D protein-coding chr2 233925089SHIP|SHIP-1|SHIP1|SIP-145|hp51CN|p150Ship inositolpolyphosphate-5-phosphatase D protein-coding chr2 233940872SHIP|SHIP-1|SHIP1|SIP-145|hp51CN|p150Ship inositolpolyphosphate-5-phosphatase D protein-coding chr2 233985212SHIP|SHIP-1|SHIP1|SIP-145|hp51CN|p150Ship inositolpolyphosphate-5-phosphatase D protein-coding chr2 233986826SHIP|SHIP-1|SHIP1|SIP-145|hp51CN|p150Ship inositolpolyphosphate-5-phosphatase D protein-coding chr2 234053819APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagy related 16 like 1protein-coding chr2 234054695 APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagyrelated 16 like 1 protein-coding chr2 234070270APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagy related 16 like 1protein-coding chr2 234070335 APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagyrelated 16 like 1 protein-coding chr2 234072847APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagy related 16 like 1protein-coding chr2 234078106 APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagyrelated 16 like 1 protein-coding chr2 234078567APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagy related 16 like 1protein-coding chr2 234078920 APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagyrelated 16 like 1 protein-coding chr2 234103983APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagy related 16 like 1protein-coding chr2 234113188 APG16L|ATG16A|ATG16L|IBD10|WDR30 autophagyrelated 16 like 1 protein-coding chr3 12837871 TIP120B|Tp120b cullinassociated and neddylation protein-coding dissociated 2 (putative) chr312838071 TIP120B|Tp120b cullin associated and neddylation protein-codingdissociated 2 (putative) chr3 12838079 TIP120B|Tp120b cullin associatedand neddylation protein-coding dissociated 2 (putative) chr3 12848532TIP120B|Tp120b cullin associated and neddylation protein-codingdissociated 2 (putative) chr3 12868845 L32|PP9932 ribosomal protein L32protein-coding chr3 42726911 KBTBD5|NEM8|SRYP|SYRP kelch like familymember 40 protein-coding chr3 111717411 NP22|NP24|NP25 transgelin 3protein-coding chr3 111717486 NP22|NP24|NP25 transgelin 3 protein-codingchr3 111717542 NP22|NP24|NP25 transgelin 3 protein-coding chr3 111717936NP22|NP24|NP25 transgelin 3 protein-coding chr3 111718095 NP22|NP24|NP25transgelin 3 protein-coding chr3 111719270 NP22|NP24|NP25 transgelin 3protein-coding chr3 111719519 NP22|NP24|NP25 transgelin 3 protein-codingchr3 128200821 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2protein-coding chr3 128206659 DCML|IMD21|MONOMAC|NFE1B GATA bindingprotein 2 protein-coding chr3 128207273 DCML|IMD21|MONOMAC|NFE1B GATAbinding protein 2 protein-coding chr3 128209391 — GATA2 antisense RNA 1ncRNA chr3 128211916 DCML|IMD21|MONOMAC|NFE1B GATA binding protein 2protein-coding chr3 128211928 DCML|IMD21|MONOMAC|NFE1B GATA bindingprotein 2 protein-coding chr3 150481064 hSiah2 siah E3 ubiquitin proteinligase 2 protein-coding chr3 150481118 hSiah2 siah E3 ubiquitin proteinligase 2 protein-coding chr3 150481164 hSiah2 siah E3 ubiquitin proteinligase 2 protein-coding chr3 151154610 CMF608 immunoglobulin superfamilymember 10 protein-coding chr3 151158459 CMF608 immunoglobulinsuperfamily member 10 protein-coding chr3 151158468 CMF608immunoglobulin superfamily member 10 protein-coding chr3 151160838CMF608 immunoglobulin superfamily member 10 protein-coding chr3151176397 CMF608 immunoglobulin superfamily member 10 protein-codingchr3 181429614 ANOP3|MCOPS3 SRY-box transcription factor 2protein-coding chr3 181429622 ANOP3|MCOPS3 SRY-box transcription factor2 protein-coding chr3 185782249 ERM ETS variant 5 protein-coding chr3185783659 ERM ETS variant 5 protein-coding chr3 185796794 ERM ETSvariant 5 protein-coding chr3 185797595 ERM ETS variant 5 protein-codingchr3 185823179 ERM ETS variant 5 protein-coding chr3 185823413 ERM ETSvariant 5 protein-coding chr3 185823631 ERM ETS variant 5 protein-codingchr3 185826233 ERM ETS variant 5 protein-coding chr3 185826239 ERM ETSvariant 5 protein-coding chr3 185826364 ERM ETS variant 5 protein-codingchr3 185826618 ERM ETS variant 5 protein-coding chr3 185826688 ERM ETSvariant 5 protein-coding chr3 185826770 ERM ETS variant 5 protein-codingchr3 185826801 ERM ETS variant 5 protein-coding chr3 185828007 ERM ETSvariant 5 protein-coding chr3 187086020 IFRG28|Z3CXXC4 receptortransporter protein 4 protein-coding chr4 6694696 M1G9 S100 calciumbinding protein P protein-coding chr4 6695505 M1G9 S100 calcium bindingprotein P protein-coding chr4 38796154 CD281|TIL|TIL. LPRS5|rsc786 tolllike receptor 1 protein-coding chr4 38805897 CD281|TIL|TIL. LPRS5|rsc786toll like receptor 1 protein-coding chr4 38806310 CD281|TIL|TIL.LPRS5|rsc786 toll like receptor 1 protein-coding chr4 38806312CD281|TIL|TIL. LPRS5|rsc786 toll like receptor 1 protein-coding chr438806340 CD281|TIL|TIL. LPRS5|rsc786 toll like receptor 1 protein-codingchr4 38806372 CD281|TIL|TIL. LPRS5|rsc786 toll like receptor 1protein-coding chr4 38806437 CD281|TIL|TIL. LPRS5|rsc786 toll likereceptor 1 protein-coding chr4 38807054 CD281|TIL|TIL. LPRS5|rsc786 tolllike receptor 1 protein-coding chr4 38807099 CD281|TIL|TIL. LPRS5|rsc786toll like receptor 1 protein-coding chr4 38858338 CD286 toll likereceptor 6 protein-coding chr4 41258330 — UCHL1 antisense RNA 1 (head tohead) ncRNA chr4 41258686 — UCHL1 antisense RNA 1 (head to head) ncRNAchr4 41258750 HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminalhydrolase L1 protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258825HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258828HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258849HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258850HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258857HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258862HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41258863HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41262556HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 41263656HEL-117|HEL-S-53|NDGOA|PARK5|PGP9.5| ubiquitin C-terminal hydrolase L1protein-coding PGP9.5|PGP95|SPG79|Uch-L1 chr4 48899120 — OCIA domaincontaining 2 protein-coding chr4 48899765 — OCIA domain containing 2protein-coding chr4 48908644 — OCIA domain containing 2 protein-codingchr4 48908674 — OCIA domain containing 2 protein-coding chr4 48908691 —OCIA domain containing 2 protein-coding chr4 48908705 — OCIA domaincontaining 2 protein-coding chr4 48908715 — OCIA domain containing 2protein-coding chr4 48908745 — OCIA domain containing 2 protein-codingchr4 48908854 — OCIA domain containing 2 protein-coding chr4 84030896C15|DGIC|PNAS-144|onzin placenta associated 8 protein-coding chr484035768 C15|DGIC|PNAS-144|onzin placenta associated 8 protein-codingchr4 84035789 C15|DGIC|PNAS-144|onzin placenta associated 8protein-coding chr4 84035855 C15|DGIC|PNAS-144|onzin placenta associated8 protein-coding chr4 84058128 C15|DGIC|PNAS-144|onzin placentaassociated 8 protein-coding chr4 177158625 ASB-5 ankyrin repeat and SOCSbox containing 5 protein-coding chr4 177162727 ASB-5 ankyrin repeat andSOCS box containing 5 protein-coding chr4 177170609 ASB-5 ankyrin repeatand SOCS box containing 5 protein-coding chr4 177190273 ASB-5 ankyrinrepeat and SOCS box containing 5 protein-coding chr4 177198622 ASB-5ankyrin repeat and SOCS box containing 5 protein-coding chr5 102089585PAL|PHM peptidylglycine alpha-amidating protein-coding monooxygenasechr5 102090271 PAL|PHM peptidylglycine alpha-amidating protein-codingmonooxygenase chr5 102090387 PAL|PHM peptidylglycine alpha-amidatingprotein-coding monooxygenase chr5 102090918 PAL|PHM peptidylglycinealpha-amidating protein-coding monooxygenase chr5 102090947 PAL|PHMpeptidylglycine alpha-amidating protein-coding monooxygenase chr5102143661 PAL|PHM peptidylglycine alpha-amidating protein-codingmonooxygenase chr5 102143667 PAL|PHM peptidylglycine alpha-amidatingprotein-coding monooxygenase chr5 102200141 PAL|PHM peptidylglycinealpha-amidating protein-coding monooxygenase chr5 102200848 PAL|PHMpeptidylglycine alpha-amidating protein-coding monooxygenase chr5102200914 PAL|PHM peptidylglycine alpha-amidating protein-codingmonooxygenase chr5 102201083 PAL|PHM peptidylglycine alpha-amidatingprotein-coding monooxygenase chr5 102201330 PAL|PHM peptidylglycinealpha-amidating protein-coding monooxygenase chr5 102201341 PAL|PHMpeptidylglycine alpha-amidating protein-coding monooxygenase chr5102201423 PAL|PHM peptidylglycine alpha-amidating protein-codingmonooxygenase chr5 102201427 PAL|PHM peptidylglycine alpha-amidatingprotein-coding monooxygenase chr5 102201614 PAL|PHM peptidylglycinealpha-amidating protein-coding monooxygenase chr5 102201661 PAL|PHMpeptidylglycine alpha-amidating protein-coding monooxygenase chr5102201720 PAL|PHM peptidylglycine alpha-amidating protein-codingmonooxygenase chr5 102202191 PAL|PHM peptidylglycine alpha-amidatingprotein-coding monooxygenase chr5 102231517 PAL|PHM peptidylglycinealpha-amidating protein-coding monooxygenase chr5 102285181 PAL|PHMpeptidylglycine alpha-amidating protein-coding monooxygenase chr5102295601 PAL|PHM peptidylglycine alpha-amidating protein-codingmonooxygenase chr5 102325375 PAL|PHM peptidylglycine alpha-amidatingprotein-coding monooxygenase chr5 102343057 GIN-1|TGIN1|ZH2C2 gypsyretrotransposon integrase 1 protein-coding chr5 102343146GIN-1|TGIN1|ZH2C2 gypsy retrotransposon integrase 1 protein-coding chr5102343163 GIN-1|TGIN1|ZH2C2 gypsy retrotransposon integrase 1protein-coding chr5 102343173 GIN-1|TGIN1|ZH2C2 gypsy retrotransposonintegrase 1 protein-coding chr6 34523991 PDEF|bA375E1.3 SAM pointeddomain containing ETS protein-coding transcription factor chr6 34524010PDEF|bA375E1.3 SAM pointed domain containing ETS protein-codingtranscription factor chr6 112451090 C6orf225 family with sequencesimilarity 229 protein-coding member B chr6 112451261 C6orf225 familywith sequence similarity 229 protein-coding member B chr6 112460378C6orf225 family with sequence similarity 229 protein-coding member Bchr6 112486266 — uncharacterized LOC10192764U ncRNA chr6 112500604 —uncharacterized LOC10192764U ncRNA chr6 112512866 — uncharacterizedLOC10192764U ncRNA chr6 112512903 — uncharacterized LOC101927640 ncRNAchr6 112512913 — uncharacterized LOC101927640 ncRNA chr6 112537550 —uncharacterized LOC101927640 ncRNA chr6 112537855 — uncharacterizedLOC101927640 ncRNA chr6 112575587 CMD1JJ|LAMA3|LAMA4*-1 laminin subunitalpha 4 protein-coding chr6 112575640 CMD1JJ|LAMA3|LAMA4*-1 lamininsubunit alpha 4 protein-coding chr6 112575674 CMD1JJ|LAMA3|LAMA4*-1laminin subunit alpha 4 protein-coding chr6 112575680CMD1JJ|LAMA3|LAMA4*-1 laminin subunit alpha 4 protein-coding chr6112575690 CMD1JJ|LAMA3|LAMA4*-1 laminin subunit alpha 4 protein-codingchr6 112575702 CMD1JJ|LAMA3|LAMA4*-1 laminin subunit alpha 4protein-coding chr6 112575749 CMD1JJ|LAMA3|LAMA4*-1 laminin subunitalpha 4 protein-coding chr6 112575812 CMD1JJ|LAMA3|LAMA4*-1 lamininsubunit alpha 4 protein-coding chr6 112575817 CMD1JJ|LAMA3|LAMA4*-1laminin subunit alpha 4 protein-coding chr6 112575824CMD1JJ|LAMA3|LAMA4*-1 laminin subunit alpha 4 protein-coding chr6112576041 CMD1JJ|LAMA3|LAMA4*-1 laminin subunit alpha 4 protein-codingchr7 148508815 ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2polycomb repressive protein-coding complex 2 subunit chr7 148580501ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581151ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581237ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581240ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581270ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581275ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581279ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr7 148581313ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2 enhancer of zeste 2 polycombrepressive protein-coding complex 2 subunit chr8 17169082HCRP1|PQBP2|SPG53 VPS37A subunit of ESCRT-1 protein-coding chr8 17169272HCRP1|PQBP2|SPG53 VPS37A subunit of ESCRT-1 protein-coding chr8 17206466— myotubularin related protein 7 protein-coding chr8 17206646 —myotubularin related protein 7 protein-coding chr8 17206894 —myotubularin related protein 7 protein-coding chr8 17270716 —myotubularin related protein 7 protein-coding chr8 17270736 —myotubularin related protein 7 protein-coding chr8 17270937 —myotubularin related protein 7 protein-coding chr8 53045604 —uncharacterized LOC101929341 ncRNA chr8 53045678 — uncharacterizedLOC101929341 ncRNA chr8 53050272 — uncharacterized LOC101929341 ncRNAchr8 53130239 — uncharacterized LOC101929341 ncRNA chr8 5313028 —uncharacterized LOC101929341 ncRNA chr8 53130282 — uncharacterizedLOC101929341 ncRNA chr8 53134555 NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18C2H2C-type zinc finger transcription protein-coding factor chr8 53159124NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53160986NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53161872NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53166808NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322203NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322209NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322216NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322232NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322252NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322265NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322339NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322342NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53322405NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 53373419NZF-3|NZF3|ZC2H2C3|ZC2HC10|ZNF387 ST18 C2H2C-type zinc fingertranscription protein-coding factor chr8 104152838 — BAALC binder ofMAP3K1 and KLF4 protein-coding chr8 104152841 — BAALC binder of MAP3K1and KLF4 protein-coding chr8 104152887 — BAALC binder of MAP3K1 and KLF4protein-coding chr8 104153026 — BAALC binder of MAP3K1 and KLF4protein-coding chr8 104165267 mir-3151 microRNA 3151 ncRNA chr8104220320 FZD6-DT|lncFZD6 BAALC antisense RNA 1 ncRNA chr8 104225459FZD6-DT|lncFZD6 BAALC antisense RNA 1 ncRNA chr8 104225539FZD6-DT|lncFZD6 BAALC antisense RNA 1 ncRNA chr10 69597717 HPANBH4|JDP1DnaJ heat shock protein family (Hsp40) protein-coding member C12 chr1069597721 HPANBH4|JDP1 DnaJ heat shock protein family (Hsp40)protein-coding member C12 chr10 69597754 HPANBH4|JDP1 DnaJ heat shockprotein family (Hsp40) protein-coding member C12 chr10 69597822HPANBH4|JDP1 DnaJ heat shock protein family (Hsp40) protein-codingmember C12 chr10 69597824 HPANBH4|JDP1 DnaJ heat shock protein family(Hsp40) protein-coding member C12 chr10 88428106CMD1C|CMH24|CMPD3|CYPHER|LDB3Z1|LDB3Z4| LIM domain binding 3protein-coding LVNC3|MFM4|ORACLE|PDLIM6|ZASP chr10 88428270CMD1C|CMH24|CMPD3|CYPHER|LDB3Z1|LDB3Z4| LIM domain binding 3protein-coding LVNC3|MFM4|ORACLE|PDLIM6|ZASP chr10 88428326CMD1C|CMH24|CMPD3|CYPHER|LDB3Z1|LDB3Z4| LIM domain binding 3protein-coding LVNC3|MFM4|ORACLE|PDLIM6|ZASP chr10 88428328CMD1C|CMH24|CMPD3|CYPHER|LDB3Z1|LDB3Z4| LIM domain binding 3protein-coding LVNC3|MFM4|ORACLE|PDLIM6|ZASP chr10 88428349CMD1C|CMH24|CMPD3|CYPHER|LDB3Z1|LDB3Z4| LIM domain binding 3protein-coding LVNC3|MFM4|ORACLE|PDLIM6|ZASP chr10 8847838710q23del|ACVRLK3|ALK3|CD292|SKR5 bone morphogenetic protein receptortype protein-coding 1A chr10 92680933ALRP|C-193|CARP|CVARP|MCARP|bA320F15.2 ankyrin repeat domain 1protein-coding chr11 60869767 LEU1|T1 CD5 molecule protein-coding chr1160869881 LEU1|T1 CD5 molecule protein-coding chr11 67350966DFN7|FAEES3|GST3|GSTP|HEL-S-22|PI glutathione S-transferase pi 1protein-coding chr11 67351113 DFN7|FAEES3|GST3|GSTP|HEL-S-22|PIglutathione S-transferase pi 1 protein-coding chr11 67351193DFN7|FAEES3|GST3|GSTP|HEL-S-22|PI glutathione S-transferase pi 1protein-coding chr11 67351495 DFN7|FAEES3|GST3|GSTP|HEL-S-22|PIglutathione S-transferase pi 1 protein-coding chr11 67351496DFN7|FAEES3|GST3|GSTP|HEL-S-22|PI glutathione S-transferase pi 1protein-coding chr11 67351505 DFN7|FAEES3|GST3|GSTP|HEL-S-22|PIglutathione S-transferase pi 1 protein-coding chr11 67351826DFN7|FAEES3|GST3|GSTP|HEL-S-22|PI glutathione S-transferase pi 1protein-coding chr11 67352166 DFN7|FAEES3|GST3|GSTP|HEL-S-22|PIglutathione S-transferase pi 1 protein-coding chr11 67353475DFN7|FAEES3|GST3|GSTP|HEL-S-22|PI glutathione S-transferase pi 1protein-coding chr11 87908501 NY-MEL-1|rrGTPbp RAB38, member RASoncogene family protein-coding chr11 87908502 NY-MEL-1|rrGTPbp RAB38,member RAS oncogene family protein-coding chr11 87908535NY-MEL-1|rrGTPbp RAB38, member RAS oncogene family protein-coding chr11112831897 CD56|MSK39|NCAM neural cell adhesion molecule 1 protein-codingchr11 112831990 CD56|MSK39|NCAM neural cell adhesion molecule 1protein-coding chr11 112832024 CD56|MSK39|NCAM neural cell adhesionmolecule 1 protein-coding chr11 112832047 CD56|MSK39|NCAM neural celladhesion molecule 1 protein-coding chr11 112832057 CD56|MSK39|NCAMneural cell adhesion molecule 1 protein-coding chr11 112832058CD56|MSK39|NCAM neural cell adhesion molecule 1 protein-coding chr11112832059 CD56|MSK39|NCAM neural cell adhesion molecule 1 protein-codingchr11 112832061 CD56|MSK39|NCAM neural cell adhesion molecule 1protein-coding chr11 112832102 CD56|MSK39|NCAM neural cell adhesionmolecule 1 protein-coding chr11 113001316 — NCAM1 antisense RNA1 ncRNAchr11 113003550 — NCAM1 antisense RNA1 ncRNA chr11 113067815 — NCAM1antisense RNA1 ncRNA chr11 113072979 — NCAM1 antisense RNA1 ncRNA chr11113072998 — NCAM1 antisense RNA1 ncRNA chr11 113102002 — NCAM1 antisenseRNA1 ncRNA chr11 113102884 — NCAM1 antisense RNA1 ncRNA chr11 113102947— NCAM1 antisense RNA1 ncRNA chr11 113103415 — NCAM1 antisense RNA1ncRNA chr11 113103417 — NCAM1 antisense RNA1 ncRNA chr11 113103766 —NCAM1 antisense RNA1 ncRNA chr11 113103880 — NCAM1 antisense RNA1 ncRNAchr11 113111129 — NCAM1 antisense RNA1 ncRNA chr11 113116730 — NCAM1antisense RNA1 ncRNA chr11 113126572 — NCAM1 antisense RNA1 ncRNA chr11113130713 — NCAM1 antisense RNA1 ncRNA chr11 113130880 — NCAM1 antisenseRNA1 ncRNA chr11 113140591 — NCAM1 antisense RNA1 ncRNA chr11 113143642— NCAM1 antisense RNA1 ncRNA chr11 133938720 JAM-2|JAM-3|JAM-C|JAMCjunctional adhesion molecule 3 protein-coding chr11 133938866JAM-2|JAM-3|JAM-C|JAMC junctional adhesion molecule 3 protein-codingchr11 133938880 JAM-2|JAM-3|JAM-C|JAMC junctional adhesion molecule 3protein-coding chr11 133996134 — small nucleolar RNA, C/D box 153 snoRNAchr11 134009435 — small nucleolar RNA, C/D box 153 snoRNA chr11134017593 — small nucleolar RNA, C/D box 153 snoRNA chr12 7022809HEL-S-279|NSE enolase 2 protein-coding chr12 7023391 HEL-S-279|NSEenolase 2 protein-coding chr12 7023514 HEL-S-279|NSE enolase 2protein-coding chr12 7023602 HEL-S-279|NSE enolase 2 protein-codingchr12 7023621 HEL-S-279|NSE enolase 2 protein-coding chr12 7023653HEL-S-279|NSE enolase 2 protein-coding chr12 7023658 HEL-S-279|NSEenolase 2 protein-coding chr12 7023661 HEL-S-279|NSE enolase 2protein-coding chr12 7023674 HEL-S-279|NSE enolase 2 protein-codingchr12 7024271 HEL-S-279|NSE enolase 2 protein-coding chr12 7026393HEL-S-279|NSE enolase 2 protein-coding chr12 7028638B37|D12S755E|DRPLA|HRS|NOD atrophin 1 protein-coding chr12 7030644B37|D12S755E|DRPLA|HRS|NOD atrophin 1 protein-coding chr12 7031052B37|D12S755E|DRPLA|HRS|NOD atrophin 1 protein-coding chr12 24983162BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25055130BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25055222BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25055909BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25101877BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25101883BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25101895BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25101920BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25102293BCATC|BCT1|ECA39|MECA39|PNAS121|PP18 branched chain amino acidtransaminase 1 protein-coding chr12 25173836 — uncharacterized LOC645177protein-coding chr12 25186593 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25188314 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205089 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205105 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205106 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205346 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205421 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205476 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205499 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205534 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205574 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25205779 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25228574 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25242608 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25249767 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25249792 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 25257163 JAW1 lymphoid restricted membrane proteinprotein-coding chr12 66582559 ASRT5|IRAKM interleukin 1 receptorassociated kinase 3 protein-coding chr12 66582875 ASRT5|IRAKMinterleukin 1 receptor associated kinase 3 protein-coding chr12 66582937ASRT5|IRAKM interleukin 1 receptor associated kinase 3 protein-codingchr12 70082891 VMD2L3 bestrophin 3 protein-coding chr12 70082956 VMD2L3bestrophin 3 protein-coding chr12 70087752 VMD2L3 bestrophin 3protein-coding chr12 70092965 VMD2L3 bestrophin 3 protein-coding chr1270093015 VMD2L3 bestrophin 3 protein-coding chr12 70093024 VMD2L3bestrophin 3 protein-coding chr12 70093031 VMD2L3 bestrophin 3protein-coding chr12 70093041 VMD2L3 bestrophin 3 protein-coding chr1270093044 VMD2L3 bestrophin 3 protein-coding chr12 70093075 VMD2L3bestrophin 3 protein-coding chr12 70093096 VMD2L3 bestrophin 3protein-coding chr12 70093156 VMD2L3 bestrophin 3 protein-coding chr12103351364 ASH1|HASH1|MASH1|bHLHa46 achaete-scute family bHLHtranscription protein-coding factor 1 chr13 102527544FGF-14|FHF-4|FHF4|SCA27 fibroblast growth factor 14 protein-coding chr13102568895 FGF-14|FHF-4|FHF4|SCA27 fibroblast growth factor 14protein-coding chr13 103054024 FGF-14|FHF-4|FHF4|SCA27 fibroblast growthfactor 14 protein-coding chr14 21994247COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spalt like transcription factor 2protein-coding chr14 21994261 COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spaltlike transcription factor 2 protein-coding chr14 21994534COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spalt like transcription factor 2protein-coding chr14 22004936 COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spaltlike transcription factor 2 protein-coding chr14 22004968COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spalt like transcription factor 2protein-coding chr14 22005138 COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spaltlike transcription factor 2 protein-coding chr14 22005250COLB|HSAL2|Sal-2|ZNF795|p150(Sal2) spalt like transcription factor 2protein-coding chr14 51448929 GSD6 glycogen phosphorylase Lprotein-coding chr14 51453070 GSD6 glycogen phosphorylase Lprotein-coding chr14 51454994 GSD6 glycogen phosphorylase Lprotein-coding chr14 51561694 RNF91|SPRING tripartite motif containing 9protein-coding chr14 51561947 RNF91|SPRING tripartite motif containing 9protein-coding chr14 51562679 RNF91|SPRING tripartite motif containing 9protein-coding chr14 75988668 B-ATF|BATF1|SFA-2|SFA2 basic leucinezipper ATF-like transcription protein-coding factor chr14 75988698B-ATF|BATF1|SFA-2|SFA2 basic leucine zipper ATF-like transcriptionprotein-coding factor chr14 75988803 B-ATF|BATF1|SFA-2|SFA2 basicleucine zipper ATF-like transcription protein-coding factor chr1493389325 CGA chromogranin A protein-coding chr14 93389402 CGAchromogranin A protein-coding chr14 93389421 CGA chromogranin Aprotein-coding chr14 93389608 CGA chromogranin A protein-coding chr1493392346 CGA chromogranin A protein-coding chr14 93397922 CGAchromogranin A protein-coding chr15 74465912 HsT17563|Meflinimmunoglobulin superfamily containing protein-coding leucine rich repeatchr15 74466371 HsT17563|Meflin immunoglobulin superfamily containingprotein-coding leucine rich repeat chr15 74466644 HsT17563|Meflinimmunoglobulin superfamily containing protein-coding leucine rich repeatchr15 74466742 HsT17563|Meflin immunoglobulin superfamily containingprotein-coding leucine rich repeat chr15 77285600CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77286921CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287326CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287363CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287365CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287367CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287372CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287413CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287603CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287626CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287653CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287660CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77287815CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77308052CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77310699CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77319966CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77320584CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77324558CD2BP1|CD2BP1L|CD2BP1S|H- proline-serine-threonine phosphataseprotein-coding PIP|PAPAS|PSTPIP interacting protein 1 chr15 77327935TM4-A|TM4SF8|TSPAN-3 tetraspanin 3 protein-coding chr16 29674500CD43|GALGP|GPL115|LSN sialophorin protein-coding chr16 29690229HEL-S-90n|QPRTase quinolinate phosphoribosyltransferase protein-codingchr16 29690258 HEL-S-90n|QPRTase quinolinate phosphoribosyltransferaseprotein-coding chr16 29690403 HEL-S-90n|QPRTase quinolinatephosphoribosyltransferase protein-coding chr16 29707018HEL-S-90n|QPRTase quinolinate phosphoribosyltransferase protein-codingchr16 31146861 CAP1|PROSTASIN serine protease 8 protein-coding chr1631146924 CAP1|PROSTASIN serine protease 8 protein-coding chr16 31146948CAP1|PROSTASIN serine protease 8 protein-coding chr16 31146983CAP1|PROSTASIN serine protease 8 protein-coding chr16 74710849FANCW|RNF201 ring finger and WD repeat domain 3 protein-coding chr1674712211 FANCW|RNF201 ring finger and WD repeat domain 3 protein-codingchr16 74712746 FANCW|RNF201 ring finger and WD repeat domain 3protein-coding chr16 74725267 hMLKL mixed lineage kinase domain likeprotein-coding pseudokinase chr16 74734588 hMLKL mixed lineage kinasedomain like protein-coding pseudokinase chr16 74734607 hMLKL mixedlineage kinase domain like protein-coding pseudokinase chr16 74734712hMLKL mixed lineage kinase domain like protein-coding pseudokinase chr1674734758 hMLKL mixed lineage kinase domain like protein-codingpseudokinase chr16 88713133 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88716622 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717296 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717323 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717338 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717339 P22-PHOχ cytochrome b-245 alpha chainprotein-coding chr16 88717343 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717349 P22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717362 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr16 88717460 p22-PHOX cytochrome b-245 alpha chainprotein-coding chr17 1665153 EPC-1|OI12|OI6|PEDF|PIG35 serpin family Fmember 1 protein-coding chr17 1665223 EPC-1|OI12|OI6|PEDF|PIG35 serpinfamily F member 1 protein-coding chr17 1665255 EPC-1|OI12|OI6|PEDF|PIG35serpin family F member 1 protein-coding chr17 1665262EPC-1|OI12|OI6|PEDF|PIG35 serpin family F member 1 protein-coding chr171665306 EPC-1|OI12|OI6|PEDF|PIG35 serpin family F member 1protein-coding chr17 1666023 EPC-1|OI12|OI6|PEDF|PIG35 serpin family Fmember 1 protein-coding chr17 1669468 EPC-1|OI12|OI6|PEDF|PIG35 serpinfamily F member 1 protein-coding chr17 1673720 EPC-1|OI12|OI6|PEDF|PIG35serpin family F member 1 protein-coding chr17 1674913EPC-1|OI12|OI6|PEDF|PIG35 serpin family F member 1 protein-coding chr171679644 EPC-1|OI12|OI6|PEDF|PIG35 serpin family F member 1protein-coding chr17 27283357 PF1 PHD finger protein 12 protein-codingchr17 27284731 PF1 PHD finger protein 12 protein-coding chr17 27287891PF1 PHD finger protein 12 protein-coding chr17 27308510 BSRPC seizurerelated 6 homolog protein-coding chr17 27308790 BSRPC seizure related 6homolog protein-coding chr17 27332831 BSRPC seizure related 6 homologprotein-coding chr17 27332981 BSRPC seizure related 6 homologprotein-coding chr17 27333063 BSRPC seizure related 6 homologprotein-coding chr17 27333216 BSRPC seizure related 6 homologprotein-coding chr17 27333358 BSRPC seizure related 6 homologprotein-coding chr17 62007774 AGM6|B29|IGB CD79b molecule protein-codingchr17 62009521 AGM6|B29|IGB CD79b molecule protein-coding chr17 62009583AGM6|B29|IGB CD79b molecule protein-coding chr17 62009591 AGM6|B29|IGBCD79b molecule protein-coding chr17 62009596 AGM6|B29|IGB CD79b moleculeprotein-coding chr17 62009614 AGM6|B29|IGB CD79b molecule protein-codingchr17 76970778 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding proteinprotein-coding BP|TANGO10B|gp90 chr17 7697097990K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76972138 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697319890K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76973305 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697582590K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76975857 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697587390K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76975890 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697589390K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76975900 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697590590K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76975909 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697591790K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr17 76975929 90K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3binding protein protein-coding BP|TANGO10B|gp90 chr17 7697609190K|BTBD17B|CyCAP|M2BP|MAC-2- galectin 3 binding protein protein-codingBP|TANGO10B|gp90 chr18 25616449 CD325|CDHN|CDw325|NCAD cadherin 2protein-coding chr18 25625460 CD325|CDHN|CDw325|NCAD cadherin 2protein-coding chr18 25677093 CD325|CDHN|CDw325|NCAD cadherin 2protein-coding chr18 25739161 CD325|CDHN|CDw325|NCAD cadherin 2protein-coding chr18 25757310 CD325|CDHN|CDw325|NCAD cadherin 2protein-coding chr18 31158479 BRPS|KIAA1713 ASXL transcriptionalregulator 3 protein-coding chr18 31158496 BRPS|KIAA1713 ASXLtranscriptional regulator 3 protein-coding chr18 31158505 BRPS|KIAA1713ASXL transcriptional regulator 3 protein-coding chr18 31158508BRPS|KIAA1713 ASXL transcriptional regulator 3 protein-coding chr1831158530 BRPS|KIAA1713 ASXL transcriptional regulator 3 protein-codingchr18 31158635 BRPS|KIAA1713 ASXL transcriptional regulator 3protein-coding chr18 31158746 BRPS|KIAA1713 ASXL transcriptionalregulator 3 protein-coding chr18 31185450 BRPS|KIAA1713 ASXLtranscriptional regulator 3 protein-coding chr18 31185451 BRPS|KIAA1713ASXL transcriptional regulator 3 protein-coding chr18 31185458BRPS|KIAA1713 ASXL transcriptional regulator 3 protein-coding chr1831185463 BRPS|KIAA1713 ASXL transcriptional regulator 3 protein-codingchr18 31185472 BRPS|KIAA1713 ASXL transcriptional regulator 3protein-coding chr18 31185490 BRPS|KIAA1713 ASXL transcriptionalregulator 3 protein-coding chr18 31187471 BRPS|KIAA1713 ASXLtranscriptional regulator 3 protein-coding chr19 39989435 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 39989507 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 39989508 SCDO1 deltalike canonical Notch ligand 3 protein-coding chr19 469167413M3|PPP1R20|p90 coiled-coil domain containing 8 protein-coding chr1951358071 APS|KLK2A1|PSA|hK3 kallikrein related peptidase 3protein-coding chr19 51358077 APS|KLK2A1|PSA|hK3 kallikrein relatedpeptidase 3 protein-coding chr19 51358086 APS|KLK2A1|PSA|hK3 kallikreinrelated peptidase 3 protein-coding chr19 51358091 APS|KLK2A1|PSA|hK3kallikrein related peptidase 3 protein-coding chr19 51358105APS|KLK2A1|PSA|hK3 kallikrein related peptidase 3 protein-coding chr1951358112 APS|KLK2A1|PSA|hK3 kallikrein related peptidase 3protein-coding chr19 51358128 APS|KLK2A1|PSA|hK3 kallikrein relatedpeptidase 3 protein-coding chr19 51360547 APS|KLK2A1|PSA|hK3 kallikreinrelated peptidase 3 protein-coding chr20 3210322BTR1|CDPD1|CHED|CHED2|NABC1|dJ794I6.2 solute carrier family 4 member 11protein-coding chr20 3211106 BTR1|CDPD1|CHED|CHED2|NABC1|dJ794I6.2solute carrier family 4 member 11 protein-coding chr20 3218273BTR1|CDPD1|CHED|CHED2|NABC1|dJ794I6.2 solute carrier family 4 member 11protein-coding chr20 3218712 BTR1|CDPD1|CHED|CHED2|NABC1|dJ794I6.2solute carrier family 4 member 11 protein-coding chr20 3219259BTR1|CDPD1|CHED|CHED2|NABC1|dJ794I6.2 solute carrier family 4 member 11protein-coding chr20 3219736 BTR1|CDPD1|CHED|CHED2|NABC1|dJ794I6.2solute carrier family 4 member 11 protein-coding chr20 5891976 SCG1chromogranin B protein-coding chr20 5892076 SCG1 chromogranin Bprotein-coding chr20 5896044 SCG1 chromogranin B protein-coding chr2020348665 IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr2022565001 HNF3B|TCF3B forkhead box A2 protein-coding chr20 22565993HNF3B|TCF3B forkhead box A2 protein-coding chr21 42839929IFI-78K|IFI78|MX|MxA MX dynamin like GTPase 1 protein-coding chr2142840664 IFI-78K|IFI78|MX|MxA MX dynamin like GTPase 1 protein-codingchr21 42878431 PP9284|PRSS10 transmembrane serine protease 2protein-coding chr21 42879809 PP9284|PRSS10 transmembrane serineprotease 2 protein-coding chr21 42879892 PP9284|PRSS10 transmembraneserine protease 2 protein-coding chr21 42879919 PP9284|PRSS10transmembrane serine protease 2 protein-coding chr21 42879941PP9284|PRSS10 transmembrane serine protease 2 protein-coding chr2142879985 PP9284|PRSS10 transmembrane serine protease 2 protein-codingchr21 42879986 PP9284|PRSS10 transmembrane serine protease 2protein-coding chr21 42902925 PP9284|PRSS10 transmembrane serineprotease 2 protein-coding chr21 42902943 PP9284|PRSS10 transmembraneserine protease 2 protein-coding chrX 49056535 MRX96|MRXSYPsynaptophysin protein-coding chrX 49056552 MRX96|MRXSYP synaptophysinprotein-coding chrX 49056554 MRX96|MRXSYP synaptophysin protein-codingchrX 49056558 MRX96|MRXSYP synaptophysin protein-coding chrX 49056618MRX96|MRXSYP synaptophysin protein-coding chrX 66764365AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4| androgen receptor protein-codingSBMA|SMAX1|TFM chrX 66764562 AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4|androgen receptor protein-coding SBMA|SMAX1|TFM chrX 66764886AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4| androgen receptor protein-codingSBMA|SMAX1|TFM chrX 66788631 AIS|AR8|DHTR|HUMARA|HYSP1|KD|NR3C4|androgen receptor protein-coding SBMA|SMAX1|TFM chr1 202039153ET(B)R-LP-2|ETBR-LP-2|ETBRLP2 G protein-coupled receptor 37 like 1protein-coding chr1 241206098 mir-3123 microRNA 3123 ncRNA chr2 89530057mir-4436a microRNA 4436a ncRNA chr3 193490472 — long intergenicnon-protein coding RNA ncRNA 2038 chr5 1548487AGPAT10|AGPAT9|AYTL2|LPCAT- lysophosphatidylcholine acyltransferase 1protein-coding 1|PFAAP3|lpcat|lysoPAFAT chr5 36521979EA6|EAAT1|GLAST|GLAST1 solute carrier family 1 member 3 protein-codingchr5 39390555 ARMD15|C9D complement C9 protein-coding chr5 71146894 CARTCART prepropeptide protein-coding chr5 142194123GRAF|GRAF1|OPHN1L|OPHN1L1 Rho GTPase activating protein 26protein-coding chr5 168573593 MIRN585|hsa-mir-585|mir-585 microRNA 585ncRNA chr7 2006579 MAD1|PIG9|TP53I9|TXBP181 mitotic arrest deficient 1like 1 protein-coding chr7 7799018 REPA3|RP-A p14 replication protein A3protein-coding chr7 127841628 MIR-129|bMIRN129-1|mir-129-1 microRNA129-1 ncRNA chr7 129912398 — carboxypeptidase A2 protein-coding chr853499560 AUGA|AUGB|FAM150A|UNQ9433 ALK and LTK ligand 1 protein-codingchr8 61990390 — hCG1816373-like ncRNA chr8 69087227 VEST-1|VEST1chromosome 8 open reading frame 34 protein-coding chr8 73479990 KV2.2potassium voltage-gated channel subfamily protein-coding B member 2 chr873849054 PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1 telomeric repeat bindingfactor 1 protein-coding chr8 133070961 PLA2L otoconin 90 protein-codingchr8 140727998 K2p9.1|KT3.2|TASK-3|TASK3 potassium two pore domainchannel protein-coding subfamily K member 9 chr8 141458926IBP|IKBKBBP|MRT13|NIBP|T1|TRS120 trafficking protein particle complex 9protein-coding chr8 141994084 FADK|FAK|FAK1|FRNK|PPP1R71|p125FAK|protein tyrosine kinase 2 protein-coding pp125FAK chr8 142367954 — Gprotein-coupled receptor 20 protein-coding chr8 143395944 — t-SNAREdomain containing 1 protein-coding chr9 36748433 — microRNA 4475 ncRNAchr9 38437314 IGFBP-RP4|IGFBPRP4|bA113O24.1 insulin like growth factorbinding protein protein-coding like 1 chr9 93792388 — uncharacterizedLOC100129316 ncRNA chr9 133769512 26RFa|P518 pyroglutamylated RFamidepeptide protein-coding chr9 134913164 CRAP34|CRSP34|CRSP8|MED3|TRAP37mediator complex subunit 27 protein-coding chr9 138719304 — calmodulinregulated spectrin associated protein-coding protein 1 chr14 100039425 —coiled-coil domain containing 85C protein-coding chr18 8660098MTCL1-AS1|MTCL1AS1 gastric cancer associated transcript 2 ncRNA chr1814917016 — long intergenic non-protein coding RNA ncRNA 1443 chr1825442246 CD325|CDHN|CDw325|NCAD cadherin 2 protein-coding chr18 47258089DSAEC acetyl-CoA acyltransferase 2 protein-coding chr20 20421462IA-1|IA1 INSM transcriptional repressor 1 protein-coding chr20 21563921— long intergenic non-protein coding RNA ncRNA 1727 chr21 32546326TIAM-1 T cell lymphoma invasion and metastasis 1 protein-coding chr2146885392 KNO|KNO1|KS collagen type XVIII alpha 1 chain protein-coding

INCORPORATION BY REFERENCE

All publications, patents, and patent applications mentioned herein arehereby incorporated by reference in their entirety as if each individualpublication, patent or patent application was specifically andindividually indicated to be incorporated by reference. In case ofconflict, the present application, including any definitions herein,will control.

Also incorporated by reference in their entirety are any polynucleotideand polypeptide sequences which reference an accession numbercorrelating to an entry in a public database, such as those maintainedby The Institute for Genomic Research (TIGR) on the World Wide Web attigr.org and/or the National Center for Biotechnology Information (NCBI)on the World Wide Web at ncbi.nlm.nih.gov.

EQUIVALENTS

Those skilled in the art will recognize, or be able to ascertain usingno more than routine experimentation, many equivalents to the specificembodiments encompassed by the present invention described herein. Suchequivalents are intended to be encompassed by the following claims.

What is claimed is:
 1. A method of assessing whether a subject isafflicted with castration-resistant neuroendocrine prosate cancer(CRPC-NE) or at risk for developing CRPC-NE, the method comprisingdetermining the presence or absence of one or more genomic or epigenomicalterations selected from: i) deletion or mutation of at least onebiomarker listed in Table 1A; ii) gain or mutation of at least onebiomarker listed in Table 1B; iii) hypermethylation of at least onegenomic site listed in Table 1C; and iv) hypomethylation of at least onegenomic site listed in Table 1D in the genomic DNA; wherein the presenceof deletion or mutation of at least one biomarker listed in Table 1A,hypermethylation of at least one genomic site listed in Table 1C, and/orhypomethylation of at least one genomic site listed in Table 1D in thegenomic DNA; and/or the absence of gain or mutation of at least onebiomarker listed in Table 1B in the genomic DNA isolated from thebiological sample indicates that the subject is afflicted with CRPC-NEor at risk for developing CRPC-NE, optionally obtaining a biologicalsample from the subject for the determination step.
 2. The method ofclaim 1, wherein the deletion or mutation of at least one biomarkerlisted in Table 1A or the gain or mutation of at least one biomarkerlisted in Table 1B is detected by whole exome sequencing (WES).
 3. Themethod of claim 1 or 2, wherein the hypermethylation of at least onegenomic site listed in Table 1C or hypomethylation of at least onegenomic site listed in Table 1D is detected by whole genome bisulfitesequencing (WGBS).
 4. The method of any one of claims 1-3, wherein thedeletion of at least one biomarker listed in Table 1A is a homozygousdeletion, a heterozygous deletion, a copy number neutral loss, or anevent defined by loss of one allele and gain of the other allele.
 5. Themethod of any one of claims 1-4, wherein the mutation of at least onebiomarker listed in Table 1A is a non-synonymous single-nucleotidevariant (SNV).
 6. The method of any one of claims 1-5, wherein the gainof at least one biomarker listed in Table 1B is a focal gain.
 7. Themethod of any one of claims 1-6, wherein the mutation of at least onebiomarker listed in Table 1B is a non-synonymous single-nucleotidevariant (SNV).
 8. The method of claim 7, wherein the mutation of atleast one biomarker listed in Table 1B is L702H or T878A of SEQ ID NO:48.
 9. The method of any one of claims 1-8, wherein the hypermethylationof at least one genomic site listed in Table 1C is defined by a highermethylation level than the site specific tissue-based threshold.
 10. Themethod of any one of claims 1-9, wherein the hypomethylation of at leastone genomic site listed in Table 1C is defined by a lower methylationlevel than the site specific tissue-based threshold.
 11. The method ofclaim 9 or 10, wherein the threshold for each genomic site listed inTable 1C or 1D is a pre-determined threshold that discriminates betweencastration resistant prostate adenocarcinoma (CRPC-Adeno) and CRPC-NEtissue samples.
 12. The method of any one of claims 1-11, furthercomprising, after step (c), calculating a neuroendocrine prostate cancer(NEPC) score based on the presence or absence of one or more genomic orepigenomic features determined in step (c).
 13. The method of claim 12,further comprising comparing the NEPC score to a control, wherein ahigher NEPC score compared to the control indicates that the subject isafflicted with CRPC-NE or at risk for developing CRPC-NE.
 14. The methodof claim 13, wherein the control is a reference value.
 15. The method ofclaim 13, wherein the control is a NEPC score determined from a controlsample.
 16. The method of claim 15, wherein the control sample isobtained from a subject without CRPC-NE, or a member of the same speciesto which the subject belongs without CRPC-NE.
 17. The method of claim 15or 16, wherein the control sample is obtained from a subject withcastration resistant prostate adenocarcinoma (CRPC-Adeno).
 18. Themethod of any one of claims 1-17, wherein the sample is selected fromthe group consisting of organs, tissue, body fluids and cells.
 19. Themethod of any one of claims 1-18, wherein the body fluid is selectedfrom the group consisting of whole blood, serum, plasma, sputum, spinalfluid, lymph fluid, skin secretions, respiratory secrections, intestinalsecretions, genitourninary tract secretions, tears, milk, buccal scrape,saliva, cerebrospinal fluid, urine, and stool.
 20. The method of any oneof claims 1-19, wherein the sample is whole blood, serum or plasma. 21.The method of any one of claims 1-20, wherein cell-free DNA (cfDNA) orcirculating tumore DNA (ctDNA) isolated from plasma is used for thedetermination.
 22. The method of any one of claims 1-21, wherein genomicDNA isolated from a tumor cell or tissue is used for the determination.23. The method of any one of claims 1-22, further comprising comparingadditional biomarkers for CRPC-NE.
 24. The method of any one of claims1-23, wherein the additional biomarker is selected from the groupconsisting of AR, a downstream AR-regulated marker, and a classicalneuroendocrine marker.
 25. The method of claim 24, wherein thedownstream AR-regulated marker is selected from the group consisting ofprostate specific antigen (PSA), NKX3.1, and TMPRSS2.
 26. The method ofclaim 24, wherein the classical neuroendocrine marker is selected fromthe group consisting of chromogranin, synaptophysin, neuron specificenolase, and CD56.
 27. The method of any one of claims 1-26, furthercomprising detecting morphological features of a tumor biopsy from thesubject.
 28. The method of any one of claims 1-27, wherein the subjectis afflicted with castration-resistant prostate cancer (CRPC).
 29. Themethod of any one of claims 1-28, wherein the subject is resistant to anandrogen receptor (AR)-directed therapy.
 30. The method of any one ofclaims 1-29, further comprising administering to the subject ananti-cancer therapy other than an AR-targeted therapy as a single agentif the subject is afflicted with CRPC-NE or at risk for developingCRPC-NE.
 31. The method of claim 30, wherein the anti-cancer therapy isselected from the group consisting of an epgenitic modifier, targetedtherapy, chemotherapy, radiation therapy, and/or hormonal therapy,optionally wherein the anti-cancer therapy comprises an AR-targetedtherapy.
 32. The method of claim 30 or 31, wherein the anti-cancertherapy is administered to the subject in combination with theAR-targeted therapy, optionally wherein the anti-cancer therapy isadministered before, after, or concurrently with the AR-targetedtherapy.
 33. The method of claim 31, wherein the targeted therapy is animmunotherapy.
 34. The method of claim 33, wherein the immunotherapy iscell-based.
 35. The method of claim 33, wherein the immunotherapycomprises a cancer vaccine and/or virus.
 36. The method of claim 33,wherein the immunotherapy inhibits an immune checkpoint.
 37. The methodof claim 36, wherein the immune checkpoint is selected from the groupconsisting of CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1, B7-H4, B7-H6,ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR family receptors, TIM-1,TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA, SIRPalpha (CD47), CD48,2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT, HHLA2, butyrophilins, andA2aR.
 38. The method of claim 37, wherein the immune checkpoint is PD1,PD-L1, or CTLA-4.
 39. The method of any one of claims 30-32, wherein theanti-cancer therapy is a platinum-based chemotherapy.
 40. A method formonitoring the progression of CRPC in a subject, the method comprising:a) detecting in a subject sample at a first point in time the presenceor absence of one or more genomic or epigenomic features selected from:i) deletion or mutation of at least one biomarker listed in Table 1A;ii) gain or mutation of at least one biomarker listed in Table 1B; iii)hypermethylation of at least one genomic site listed in Table 1C; andiv) hypomethylation of at least one genomic site listed in Table 1D; b)calculating a first NEPC score based on the presence or absence of oneor more genomic or epigenomic features determined in step a); c)repeating step a) at a subsequent point in time; d) calculating a secondNEPC score based on the presence or absence of one or more genomic orepigenomic features determined in step c); and e) comparing the NEPCscores determined in steps b) and d), and therefrom monitoring theprogression of CRPC in the subject.
 41. A method of assessing theefficacy of an agent for treating CRPC-NE in a subject, the methodcomprising: a) detecting in a subject sample at a first point in timethe presence or absence of one or more genomic or epigenomic featuresselected from: i) deletion or mutation of at least one biomarker listedin Table 1A; ii) gain or mutation of at least one biomarker listed inTable 1B; iii) hypermethylation of at least one genomic site listed inTable 1C; and iv) hypomethylation of at least one genomic site listed inTable 1D; b) calculating a first NEPC score based on the presence orabsence of one or more genomic or epigenomic features determined in stepa); c) repeating step a) during at least one subsequent point in timeafter administration of the agent; d) calculating a second NEPC scorebased on the presence or absence of one or more genomic or epigenomicfeatures determined in step c); and e) comparing the NEPC scoresdetermined from steps b) and d), wherein a higher NEPC score determinedin the subsequent sample, relative to the sample at the first point intime, indicates that the agent does not treat CRPC-NE in the subject;and wherein a lower NEPC score determined in the subsequent sample,relative to the sample at the first point in time, indicates that theagent treats CRPC-NE in the subject.
 42. The method of claim 40 or 41,wherein between the first point in time and the subsequent point intime, the subject has undergone treatment, completed treatment, and/oris in remission for CRPC-NE.
 43. The method of any one of claims 40-42,wherein the first and/or at least one subsequent sample is selected fromthe group consisting of ex vivo and in vivo samples.
 44. The method ofany one of claims 40-43, wherein the first and/or at least onesubsequent sample is obtained from an animal model of CRPC-NE.
 45. Themethod of any one of claims 40-44, wherein the first and/or at least onesubsequent sample is a portion of a single sample or pooled samplesobtained from the subject.
 46. The method of any one of claims 40-45,wherein the sample comprises cells, cell lines, histological slides,paraffin embedded tissue, fresh frozen tissue, fresh tissue, biopsies,blood, plasma, serum, buccal scrape, saliva, cerebrospinal fluid, urine,stool, mucus, bone marrow, peritumoral tissue, and/or intratumoraltissue obtained from the subject.
 47. The method of any one of claims40-46, wherein the sample is whole blood, serum or plasma.
 48. Themethod of claim 46, wherein the sample is a tumor cell or tissue, andgenomic DNA is isolated from the plasma and used for detecting thepresence or absence of one or more genomic or epigenomic features. 49.The method of claim 47, wherein the sample is plasma, and cell-free DNA(cfDNA) or circulating tumore DNA (ctDNA) is isolated from the plasmaand used for detecting the presence or absence of one or more genomic orepigenomic features.
 50. A cell-based assay for screening for agentsthat have a cytotoxic or cytostatic effect on a CRPC-NE cancer cellcomprising, contacting the CRPC-NE cancer cell with a test agent, anddetermining the ability of the teat agent: i) to inhibit deletion ormutation of at least one biomarker listed in Table 1A; ii) to inducegain or mutation of at least one biomarker listed in Table 1B; iii) todecrease the methylation level at least one genomic site listed in Table1C; and/or iv) to increase the methylation level of at least one genomicsite listed in Table 1D in the subject sample.
 51. The cell-based assayof claim 52, wherein the step of contacting occurs in vivo, ex vivo, orin vitro.
 52. The cell-based assay of claim 51 or 52, further comprisingadministering the test agent to an animal model of CRPC-NE.
 53. A kitfor assessing the ability of a agent to treat CRPC-NE, the kitcomprising a reagent for assessing the presence or absence of one ormore genomic or epigenomic features selected from: i) deletion ormutation of at least one biomarker listed in Table 1A; ii) gain ormutation of at least one biomarker listed in Table 1B; iii)hypermethylation of at least one genomic site listed in Table 1C; andiv) hypomethylation of at least one genomic site listed in Table 1D. 54.A kit for assessing whether a subject is afflicted with CRPC-NE or atrisk for developing CRPC-NE, the kit comprising a reagent for assessingthe presence or absence of one or more genomic or epigenomic featuresselected from: i) deletion or mutation of at least one biomarker listedin Table 1A; ii) gain or mutation of at least one biomarker listed inTable 1B; iii) hypermethylation of at least one genomic site listed inTable 1C; and iv) hypomethylation of at least one genomic site listed inTable 1D.
 55. A method of treating a subject afflicted with CRPC-NEcomprising administering to the subject a therapeutically effectiveamount of an agent that modulates the presence or absence of one or moregenomic or epigenomic features selected from: i) deletion or mutation ofat least one biomarker listed in Table 1A; ii) gain or mutation of atleast one biomarker listed in Table 1B; iii) hypermethylation of atleast one genomic site listed in Table 1C; and iv) hypomethylation of atleast one genomic site listed in Table 1D.
 56. The method of claim 55,wherein the agent inhibits deletion or mutation of at least onebiomarker listed in Table 1A, thereby treating a subject afflicted withCRPC-NE.
 57. The method of claim 55, wherein the agent induces gain ormutation of at least one biomarker listed in Table 1B, thereby treatinga subject afflicted with CRPC-NE.
 58. The method of claim 55, whereinthe agent decreases the methylation level at least one genomic sitelisted in Table 1C, thereby treating a subject afflicted with CRPC-NE.59. The method of claim 55, wherein the agent increases the methylationlevel at least one genomic site listed in Table 1D, thereby treating asubject afflicted with CRPC-NE.
 60. The method of claim 58 or 59,wherein the agent is an epigenetic modifier.
 61. The method of claim 60,wherein the epigenetic modifier is an EZH2 inhibitor.
 62. The method ofany one of claims 55-61, further comprising administering to the subjectan immunotherapy and/or cancer therapy, optionally wherein theimmunotherapy and/or cancer therapy is administered before, after, orconcurrently with the agent.
 63. The method of claim 62, wherein theimmunotherapy is cell-based.
 64. The method of claim 62, wherein theimmunotherapy comprises a cancer vaccine and/or virus.
 65. The method ofclaim 62, wherein the immunotherapy inhibits an immune checkpoint. 66.The method of claim 65, wherein the immune checkpoint is selected fromthe group consisting of CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1, B7-H4,B7-H6, ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR family receptors,TIM-1, TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA, SIRPalpha (CD47),CD48, 2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT, HHLA2,butyrophilins, and A2aR.
 67. The method of claim 66, wherein the immunecheckpoint is PD1, PD-L1, or CD47.
 68. The method of claim 62, whereinthe cancer therapy is selected from the group consisting of radiation, aradiosensitizer, and a chemotherapy.
 69. The method of claim 68, whereinthe cancer therapy is a platinum-based chemotherapy.
 70. The method orassay of any one of claims 40-69, wherein the deletion or mutation of atleast one biomarker listed in Table 1A or the gain or mutation of atleast one biomarker listed in Table 1B is detected by whole exomesequencing (WES).
 71. The method or assay of any one of claims 40-70,wherein the hypermethylation of at least one genomic site listed inTable 1C or hypomethylation of at least one genomic site listed in Table1D is detected by whole genome bisulfate sequencing (WGBS).
 72. Themethod or assay of any one of claims 40-71, wherein the deletion of atleast one biomarker listed in Table 1A is a homozygous deletion, aheterozygous deletion, a copy number neutral loss, or an event definedby loss of one allele and gain of the other allele.
 73. The method orassay of any one of claims 40-72, wherein the mutation of at least onebiomarker listed in Table 1A is a non-synonymous single-nucleotidevariant (SNV).
 74. The method or assay of any one of claims 40-73,wherein the gain of at least one biomarker listed in Table 1B is a focalgain.
 75. The method or assay of any one of claims 40-74, wherein themutation of at least one biomarker listed in Table 1B is anon-synonymous single-nucleotide variant (SNV).
 76. The method or assayof claim 75, wherein the mutation of at least one biomarker listed inTable 1B is L702H or T878A of SEQ ID NO:
 48. 77. The method or assay ofany one of claims 40-76, wherein the hypermethylation of at least onegenomic site listed in Table 1C is defined by a higher methylation levelthan the site specific tissue-based threshold.
 78. The method or assayof any one of claims 40-77, wherein the hypomethylation of at least onegenomic site listed in Table 1C is defined by a lower methylation levelthan the site specific tissue-based threshold.
 79. The method or assayof any one of claims 40-78, wherein the threshold for each genomic sitelisted in Table 1C or 1D is the threshold that best discriminatesbetween castration resistant prostate adenocarcinoma (CRPC-Adeno) andCRPC-NE tissue samples by Receiver operating characteristic (ROC) curveanalysis.
 80. A method of assessing whether a subject is afflicted withor at risk for developing castration-resistant neuroendocrine prostatecancer (CRPC-NE) or castration-resistant adenocarcinoma prostate cancer(CRPC-Adeno), the method comprising determining the presence or absenceof one or more genomic or epigenomic alterations in at least onebiomarker listed in Table 14, wherein the presence one or more genomicor epigenomic alterations listed in Table 14 in the genomic DNA isolatedfrom the biological sample indicates that the subject is afflicted withCRPC-NE or CRPC-Adeno or at risk for developing CRPC-NE or CRPC-Adeno,optionally obtaining a biological sample from the subject for thedetermination step.
 81. The method of claim 80, wherein the one or moregenomic or epigenomic alterations listed in Table 14 comprises amutation detected by whole exome sequencing (WES).
 82. The method ofclaim 80, wherein the one or more genomic or epigenomic alterationslisted in Table 14 comprises hypermethylation or hypomethylation of atleast one genomic site listed in Table 14 detected by whole genomebisulfite sequencing (WGBS).
 83. The method of claim 80, wherein the oneor more genomic or epigenomic alterations listed in Table 14 comprise ahomozygous deletion, a heterozygous deletion, a copy number neutralloss, or an event defined by loss of one allele and gain of the otherallele.
 84. The method of claim 80, wherein the one or more genomic orepigenomic alterations listed in Table 14 is a non-synonymoussingle-nucleotide variant (SNV).
 85. The method of claim 80, wherein theone or more genomic or epigenomic alterations listed in Table 14 is afocal gain of at least one biomarker listed in Table 14
 86. The methodof claim 80, wherein the one or more genomic or epigenomic alterationslisted in Table 14 is a non-synonymous single-nucleotide variant (SNV).87. The method of claim 82, wherein the hypermethylation of at least onegenomic site listed in Table 14 is defined by a higher methylation levelthan the site specific tissue-based threshold.
 88. The method of claim82, wherein the hypomethylation of at least one genomic site listed inTable 14 is defined by a lower methylation level than the site specifictissue-based threshold.
 89. The method of claim 87 or 88, wherein thethreshold for each genomic site listed in Table 14 is a pre-determinedthreshold that discriminates between castration resistant prostateadenocarcinoma (CRPC-Adeno) and CRPC-NE tissue samples.
 90. The methodof any one of claims 80-89 further comprising, after step (c),calculating a neuroendocrine prostate cancer (NEPC) score based on thepresence or absence of one or more genomic or epigenomic featuresdetermined in step (c).
 91. The method of claim 90, further comprisingcomparing the NEPC score to a control, wherein a higher NEPC scorecompared to the control indicates that the subject is afflicted withCRPC-NE or at risk for developing CRPC-NE.
 92. The method of claim 91,wherein the control is a reference value.
 93. The method of claim 91,wherein the control is a NEPC score determined from a control sample.94. The method of claim 93, wherein the control sample is obtained froma subject without CRPC-NE, or a member of the same species to which thesubject belongs without CRPC-NE.
 95. The method of claim 93 or 94,wherein the control sample is obtained from a subject with castrationresistant prostate adenocarcinoma (CRPC-Adeno).
 96. The method of anyone of claims 80-95, wherein the sample is selected from the groupconsisting of organs, tissue, body fluids and cells.
 97. The method ofany one of claims 80-96, wherein the body fluid is selected from thegroup consisting of whole blood, serum, plasma, sputum, spinal fluid,lymph fluid, skin secretions, respiratory secrections, intestinalsecretions, genitourninary tract secretions, tears, milk, buccal scrape,saliva, cerebrospinal fluid, urine, and stool.
 98. The method of any oneof claims 80-97, wherein the sample is whole blood, serum or plasma. 99.The method of any one of claims 80-98, wherein cell-free DNA (cfDNA) orcirculating tumore DNA (ctDNA) isolated from plasma is used for thedetermination.
 100. The method of any one of claims 80-99, whereingenomic DNA isolated from a tumor cell or tissue is used for thedetermination.
 101. The method of any one of claims 80-100, furthercomprising comparing additional biomarkers for CRPC-NE.
 102. The methodof any one of claims 80-101, wherein the additional biomarker isselected from the group consisting of AR, a downstream AR-regulatedmarker, and a classical neuroendocrine marker.
 103. The method of claim102, wherein the downstream AR-regulated marker is selected from thegroup consisting of prostate specific antigen (PSA), NKX3.1, andTMPRSS2.
 104. The method of claim 102, wherein the classicalneuroendocrine marker is selected from the group consisting ofchromogranin, synaptophysin, neuron specific enolase, and CD56.
 105. Themethod of any one of claims 80-104, further comprising detectingmorphological features of a tumor biopsy from the subject.
 106. Themethod of any one of claims 80-105, wherein the subject is afflictedwith castration-resistant prostate cancer (CRPC).
 107. The method of anyone of claims 80-106, wherein the subject is resistant to an androgenreceptor (AR)-directed therapy.
 108. The method of any one of claims80-107, further comprising administering to the subject an anti-cancertherapy other than an AR-targeted therapy as a single agent if thesubject is afflicted with CRPC-NE or at risk for developing CRPC-NE.109. The method of claim 108, wherein the anti-cancer therapy isselected from the group consisting of an epgenitic modifier, targetedtherapy, chemotherapy, radiation therapy, and/or hormonal therapy,optionally wherein the anti-cancer therapy comprises an AR-targetedtherapy.
 110. The method of claim 108 or 109, wherein the anti-cancertherapy is administered to the subject in combination with theAR-targeted therapy, optionally wherein the anti-cancer therapy isadministered before, after, or concurrently with the AR-targetedtherapy.
 111. The method of claim 110, wherein the targeted therapy isan immunotherapy.
 112. The method of claim 111, wherein theimmunotherapy is cell-based.
 113. The method of claim 111, wherein theimmunotherapy comprises a cancer vaccine and/or virus.
 114. The methodof claim 111, wherein the immunotherapy inhibits an immune checkpoint.115. The method of claim 114, wherein the immune checkpoint is selectedfrom the group consisting of CTLA-4, PD-1, VISTA, B7-H2, B7-H3, PD-L1,B7-H4, B7-H6, ICOS, HVEM, PD-L2, CD160, gp49B, PIR-B, KIR familyreceptors, TIM-1, TIM-3, TIM-4, LAG-3, GITR, 4-IBB, OX-40, BTLA,SIRPalpha (CD47), CD48, 2B4 (CD244), B7.1, B7.2, ILT-2, ILT-4, TIGIT,HHLA2, butyrophilins, and A2aR.
 116. The method of claim 114, whereinthe immune checkpoint is PD1, PD-L1, or CTLA-4.
 117. The method of anyone of claims 114-116, wherein the anti-cancer therapy is aplatinum-based chemotherapy.
 118. The method or assay of any one ofclaims 1-117, wherein the agent is administered in a pharmaceuticallyacceptable formulation.
 119. The method or assay of any one of claims1-118, wherein the subject is an animal model of CRPC-NE.
 120. Themethod or assay of claim 119, wherein the animal model is a rodentmodel.
 121. The method or assay of any one of claims 1-119, wherein thesubject is a mammal.
 122. The method or assay of any one of claims1-121, wherein the mammal is a mouse or a human.
 123. The method orassay of any one of claims 1-122, wherein the mammal is a human.